Publications
| Title | Abstract | Year Filter | PMID(sorted ascending) Filter |
|---|
| antimicrobial activity of actinobacteria isolated from the guts of subterranean termites. | subterranean termites need to minimize potentially pathogenic and competitive fungi in their environment in order to maintain colony health. we examined the ability of actinobacteria isolated from termite guts in suppressing microorganisms commonly encountered in a subterranean environment. guts from two subterranean termite species, reticulitermes flavipes (kollar) and reticulitermes tibialis banks, were extracted and plated on selective chitin media. a total of 38 actinobacteria isolates were ... | 2016 | 27680020 |
| carbon-starvation induces cross-resistance to thermal, acid, and oxidative stress in serratia marcescens. | the broad host-range pathogen serratia marcescens survives in diverse host and non-host environments, often enduring conditions in which the concentration of essential nutrients is growth-limiting. in such environments, carbon and energy source starvation (carbon-starvation) is one of the most common forms of stress encountered by s. marcescens. related members of the family enterobacteriaceae are known to undergo substantial changes in gene expression and physiology in response to the specific ... | 2015 | 27682115 |
| endophthalmitis after cataract surgery despite intracameral antibiotic prophylaxis with licensed cefuroxime. | to report a case series of post-phacoemulsification endophthalmitis despite antibiotic prophylaxis with an intracameral injection of a licensed cefuroxime formulation (aprokam). | 2016 | 27697250 |
| enhancing activity and thermostability of lipase a from serratia marcescens by site-directed mutagenesis. | lipases as significant biocatalysts had been widely employed to catalyze various chemical reactions such as ester hydrolysis, ester synthesis, and transesterification. improving the activity and thermostability of enzymes is desirable for industrial applications. the lipase of serratia marcescens belonging to family i.3 lipase has a very important pharmaceutical application in production of chiral precursors. in the present study, to achieve improved lipase activity and thermostability, using co ... | 2016 | 27702479 |
| piper betle and its bioactive metabolite phytol mitigates quorum sensing mediated virulence factors and biofilm of nosocomial pathogen serratia marcescens in vitro. | piper betle, a tropical creeper plant belongs to the family piperaceae. the leaves of this plant have been well known for their therapeutic, religious and ceremonial value in south and southeast asia. it has also been reported to possess several biological activities including antimicrobial, antioxidant, antinociceptive, antidiabetic, insecticidal and gastroprotective activities and used as a common ingredient in indigenous medicines. in indian system of ayurvedic medicine, p. betle has been wel ... | 2016 | 27721053 |
| corneal ring infiltrates caused by serratia marcescens in a patient with human immunodeficiency virus. | to describe corneal ring infiltrates caused by serratia marcescens in a patient with human immunodeficiency virus (hiv-1) who wore contact lenses. | 2017 | 27721784 |
| coexistence of free-living amoebae and bacteria in selected south african hospital water distribution systems. | pathogenic free-living amoebae (fla), such as naegleria fowleri, balamuthia mandrillaris and acanthamoeba species isolated from aquatic environments have been implicated in central nervous system, eye and skin human infections. they also allow the survival, growth and transmission of bacteria such as legionella, mycobacteria and vibrio species in water systems. the purpose of this study was to investigate the co-occurrence of potentially pathogenic fla and their associated bacteria in hospital w ... | 2017 | 27730363 |
| bacteriological assessment of pneumonia caused by gram-negative bacteria in patients hospitalized in intensive care unit. | the article presents the results of 11-year study (2005-2015) of gram-negative bacteria responsible for pneumonia in 2033 mechanically ventilated patients hospitalized in intensive care unit. of 8796 biological samples, consisting mainly of bronchial aspirate (97.9 %), 2056 bacterial strains were isolated and subjected to identification. vitek 2 was used to determine drug susceptibility (classified according to the eucast criteria). esbl, mbl and kpc-producing strains were identified by means of ... | 2017 | 27739023 |
| current state of resistance to antibiotics of last-resort in south africa: a review from a public health perspective. | a review of the literature was undertaken to delineate the current level and mechanisms of resistance to carbapenems, colistin, and tigecycline in south africa. thirty-two english publications and 32 national institute of communicable diseases communiqués identified between early january 2000 and 20 may, 2016 showed substantial reports of ndm (n = 860), oxa-48 (n = 584), vim (n = 131), and imp (n = 45) carbapenemases within this period, mainly in klebsiella pneumoniae (n = 1138), acinetobacter b ... | 2016 | 27747206 |
| [increasing incidence of community-acquired pneumonia caused by atypical microorganisms]. | knowing the most common microorganisms in our environment can help us to make proper empirical treatment decisions. the aim is to identify those microorganisms causing community-acquired pneumonia. | 2016 | 27773623 |
| the role of dna amplification and cultural growth in complicated acute appendicitis. | bacterial growth of peritoneal fluid specimens obtained during surgical procedures for acute appendicitis may be useful to optimize further antibiotic therapy in complicated cases. dna amplification represents a fast technique to detect microbial sequences. we aimed to compare the potential of dna amplification versus traditional bacterial growth culture highlighting advantages and drawbacks in a surgical setting. peritoneal fluid specimens were collected during surgery from 36 children who unde ... | 2016 | 27777701 |
| evaluation of the antibacterial and antioxidant activities of chitosan edible films incorporated with organic essential oils obtained from four thymus species. | the aims of this study were to evaluate, (1) the antibacterial properties, (2) the total phenol content and (3) the antioxidant activity, of chitosan edible films incorporated with certified organic essential oils (eos) obtained from thymus zygis, thymus mastichina, thymus capitatus and thymus vulgaris. the agar disc diffusion method was used to determine the antibacterial activities of chitosan edible films while for the antioxidant activity, two different analytical assays were used (dpph and ... | 2016 | 27784932 |
| uncoupling of an ammonia channel as a mechanism of allosteric inhibition in anthranilate synthase of serratia marcescens: dynamic and graph theoretical analysis. | anthranilate synthase (as) is the first branch node enzyme that catalyzes the conversion of chorismate to anthranilate in the high energy-consuming tryptophan biosynthetic pathway in serratia marcescens. as, with an allosterically-bound inhibitor (tryptophan), shows complete inhibition in its catalytic function, but the inhibitor-bound structure is very similar to that of the substrate-bound as. even though the reaction mechanisms of several chorismate-utilizing enzymes are known, the unusual st ... | 2016 | 27833951 |
| an iron detection system determines bacterial swarming initiation and biofilm formation. | iron availability affects swarming and biofilm formation in various bacterial species. however, how bacteria sense iron and coordinate swarming and biofilm formation remains unclear. using serratia marcescens as a model organism, we identify here a stage-specific iron-regulatory machinery comprising a two-component system (tcs) and the tcs-regulated iron chelator 2-isocyano-6,7-dihydroxycoumarin (icdh-coumarin) that directly senses and modulates environmental ferric iron (fe(3+)) availability to ... | 2016 | 27845335 |
| synergistic reaction of silver nitrate, silver nanoparticles, and methylene blue against bacteria. | in this paper we describe the antibacterial effect of methylene blue, mb, and silver nitrate reacting alone and in combination against five bacterial strains including serratia marcescens and escherichia coli bacteria. the data presented suggest that when the two components are combined and react together against bacteria, the effects can be up to three orders of magnitude greater than that of the sum of the two components reacting alone against bacteria. analysis of the experimental data provid ... | 2016 | 27849602 |
| adolescent with recurrent tuberculosis: can it be chronic granulomatous disease? | chronic granulomatous disease (cgd) is an inherited primary immunodeficiency disorder with recurrent bacterial and fungal infections like staphylococcus aureus, nocardia spp, serratia marcescens, burkholderia cepacia, salmonella spp. and aspergillus species. we present a 13-year-old male child who had 3 episodes of tuberculosis (tb) at 5 years, 8 years and 13 years of age, respectively, with no other intercurrent infections and who was diagnosed as cgd at the age of 13 years. this case highlight ... | 2016 | 27865245 |
| a case of septic shock due to serratia marcescens pyelonephritis and bacteremia in a patient receiving empagliflozin. | sodium-glucose cotransporter 2 (sglt2) inhibitors have been associated with serious urinary tract infections (utis) including pyelonephritis and urosepsis. the food and drug administration (fda) issued a label change to include this warning in december 2015 due to a small number of cases (n = 19) reported to the fda adverse event reporting system. details of these cases are limited and none involved empagliflozin. to date, there has been no published literature comprehensively describing serious ... | 2016 | 27876693 |
| enterocyte purge and rapid recovery is a resilience reaction of the gut epithelium to pore-forming toxin attack. | besides digesting nutrients, the gut protects the host against invasion by pathogens. enterocytes may be subjected to damage by both microbial and host defensive responses, causing their death. here, we report a rapid epithelial response that alleviates infection stress and protects the enterocytes from the action of microbial virulence factors. intestinal epithelia exposed to hemolysin, a pore-forming toxin secreted by serratia marcescens, undergo an evolutionarily conserved process of thinning ... | 2016 | 27889464 |
| tailoring shape and size of biogenic silver nanoparticles to enhance antimicrobial efficacy against mdr bacteria. | spherical, rectangular, penta, and hexagonal silver nanoparticles of different dimensions were biosynthesized in an eco-friendly manner by biocontrol agent, trichoderma viride by manipulating physical parameters, ph, temperature, and reaction time. the particles were characterized by uv-vis spectroscopy; dynamic light scattering (dls), transmission electron microscopy (tem) and fourier transform infra-red spectroscopy (ftir). shape and size dependent antimicrobial activity of nanoparticles again ... | 2017 | 27889528 |
| searching for a potential antibacterial lead structure against bacterial biofilms among new naphthoquinone compounds. | the aims of this study were to design, synthesize and to evaluate 2-hydroxy-3-phenylsulfanylmethyl-[1,4]-naphthoquinones against gram-negative and gram-positive bacterial strains, including methicillin-resistant staphylococcus aureus (mrsa) and its biofilm, to probe for potential lead structures. | 2017 | 27930849 |
| draft genome sequence of a ges-5-producing serratia marcescens isolated in southern brazil. | serratia marcescens is a gram-negative rod intrinsically resistant to polymyxins and usually associated with wound, respiratory and urinary tract infections. the whole genome of the first ges-5-producing s. marcescens isolated from a brazilian patient was sequenced using ion torrent pgm system. besides blages-5, we were able to identify genes encoding for other β-lactamases, for aminoglycoside modifying enzymes and for an efflux pump to tetracyclines. | 2017 | 27932081 |
| metabolic engineering of serratia marcescens mg1 for enhanced production of (3r)-acetoin. | optically pure acetoin (ac) is an important platform chemical which has been widely used to synthesize novel optically active α-hydroxyketone derivatives and liquid crystal composites. | 2016 | 27942437 |
| bioremediation of polycyclic aromatic hydrocarbon (pah) compounds: (acenaphthene and fluorene) in water using indigenous bacterial species isolated from the diep and plankenburg rivers, western cape, south africa. | this study was conducted to investigate the occurrence of pah degrading microorganisms in two river systems in the western cape, south africa and their ability to degrade two pah compounds: acenaphthene and fluorene. a total of 19 bacterial isolates were obtained from the diep and plankenburg rivers among which four were identified as acenaphthene and fluorene degrading isolates. in simulated batch scale experiments, the optimum temperature for efficient degradation of both compounds was determi ... | 2016 | 27956015 |
| protracted regional dissemination of gim-1-producing serratia marcescens in western germany. | the metallo-beta-lactamase gim-1 has been found in various bacterial host species nearly exclusively in western germany. however, not much is known about the epidemiology of gim-1-positive serratia marcescens here we report on a surprisingly protracted regional dissemination. in-hospital transmission was investigated by using conventional epidemiological tools to identify spatiotemporal links. strain typing was performed using pulsed-field gel electrophoresis (pfge) and whole-genome sequencing ( ... | 2017 | 27956426 |
| effect of encapsulation on antimicrobial activity of herbal extracts with lysozyme. | resistance of microorganisms to antibiotics has increased. the use of natural components with antimicrobial properties can be of great significance to reduce this problem. the presented work is focused on the study of the effect of encapsulation of selected plant and animal antimicrobial substances (herbs, spices, lysozyme and nisin) on their activity and stability. antimicrobial components were packaged into liposomes and polysaccharide particles (alginate, chitosan and starch). antimicrobial a ... | 2016 | 27956862 |
| the preparation and characterization of chitin and chitosan under large-scale submerged fermentation level using shrimp by-products as substrate. | the crustacean shells of crabs and shrimps produces quantities of by-products, leading to seriously environmental pollution and human health problems during industrial processing, yet they turned into high-value useful products, such as chitin and chitosan. to prepare them under large-scale submerged fermentation level, shrimp shell powders (ssps) was fermented by successive three-step fermentation of serratia marcescens b742, lactobacillus plantarum atcc 8014 and rhizopus japonicus m193 to extr ... | 2017 | 27965127 |
| arsenic resistance strategy in pantoea sp. imh: organization, function and evolution of ars genes. | pantoea sp. imh is the only bacterium found in genus pantoea with a high as resistance capacity, but its molecular mechanism is unknown. herein, the organization, function, and evolution of ars genes in imh are studied starting with analysis of the whole genome. two ars systems - ars1 (arsr1b1c1h1) and ars2 (arsr2b2c2h2) - with low sequence homology and two arsc-like genes, were found in the imh genome. both ars1 and ars2 are involved in the as resistance, where ars1 is the major contributor at ... | 2016 | 27966630 |
| pore-forming toxins trigger the purge. | the intestinal epithelium responds to pathogens by coordinating microbial elimination with tissue repair, both required to survive an infection. in this issue of cell host & microbe, lee et al. (2016) discover a rapid and evolutionarily conserved response to pore-forming toxins in the gut, involving cytoplasm ejection and enterocyte regrowth. | 2016 | 27978428 |
| emerging trends of bloodstream infections: a six-year study at a paediatric tertiary care hospital in kabul. | to determine the frequency of pathogens causing bloodstream infections and evaluate their trends and antibiogram patterns among in-patients in a paediatric tertiary care centre. | 2016 | 27981921 |
| extraction and encapsulation of prodigiosin in chitosan microspheres for targeted drug delivery. | the encapsulation of drugs in polymeric materials has brought opportunities to the targeted delivery of chemotherapeutic agents. these polymeric delivery systems are capable of maximizing the therapeutic activity, as well as reducing the side effects of anti-cancer agents. prodigiosin, a secondary metabolite extracted from the bacteria, serratia marcescens, exhibits anti-cancer properties. prodigiosin-loaded chitosan microspheres were prepared via water-in-oil (w/o) emulsion technique, using glu ... | 2017 | 27987708 |
| characterization of putative virulence factors of serratia marcescens strain sen for pathogenesis in spodoptera litura. | two serratia marcescens strains, sen and icc-4, isolated from diseased insect cadavers were observed to differ considerably in their virulence towards spodoptera litura. the present study was aimed to characterize the possible virulence factors present in the virulent serratia marcescens strain sen. both the s. marcescens strains were evaluated for the presence of various lytic enzymes such as chitinase, lipase, protease and phospholipase. the virulent s. marcescens strain sen was observed to po ... | 2017 | 27993620 |
| computational identification of potent inhibitors for streptomycin 3″-adenylyltransferase of serratia marcescens. | serratia marcescens is an opportunistic pathogen responsible for the respiratory and urinary tract infections in humans. the antibiotic resistance mechanism of s. marcescens is mediated through aminoglycoside modification enzyme that transfer adenyl group from substrate to antibiotic through regiospecific transfers for the inactivation of antibiotics. streptomycin 3(″)-adenylyltransferase acts on the 3' position of the antibiotic and considered as a novel drug target to overcome bacterial antibi ... | 2017 | 27993702 |
| the enemy within: phloem-limited pathogens. | the growing impact of phloem-limited pathogens on high-value crops has led to a renewed interest in understanding how they cause disease. although these pathogens cause substantial crop losses, many are poorly characterized. in this review, we present examples of phloem-limited pathogens that include intracellular bacteria with and without cell walls, and viruses. phloem-limited pathogens have small genomes and lack many genes required for core metabolic processes, which is, in part, an adaptati ... | 2016 | 27997761 |
| neonatal bacterial conjunctivitis in korea in the 21st century. | to investigate the microbial cause and antibiotic susceptibility of neonatal bacterial conjunctivitis in korean patients in the 21st century. | 2017 | 28002109 |
| sepsis and hemocyte loss in honey bees (apis mellifera) infected with serratia marcescens strain sicaria. | global loss of honey bee colonies is threatening the human food supply. diverse pathogens reduce honey bee hardiness needed to sustain colonies, especially in winter. we isolated a free-living gram negative bacillus from hemolymph of worker honey bees (apis mellifera) found separated from winter clusters. in some hives, greater than 90% of the dying bees detached from the winter cluster were found to contain this bacterium in their hemolymph. throughout the year, the same organism was rarely fou ... | 2016 | 28002470 |
| manual resuscitators in successive use in the same patient: reservoir of multi- and extensively resistant bacteria. | to determine the bacterial load on manual resuscitators (mrs), swab samples of mr connectors from a brazilian intensive care unit were collected at time zero, and after 24 and 48h use in the same patient. from 20 mrs, a total of 54 bacteria were isolated: six at t=0, 17 at t=24, and 31 at t=48. staphylococcus aureus, acinetobacter baumannii, serratia marcescens, and pseudomonas aeruginosa were the predominant isolates, and multidrug resistance was widespread in all species. greater awareness of ... | 2017 | 28012582 |
| bacteria associated with piezodorus guildinii (hemiptera: pentatomidae), with special reference to those transmitted by feeding. | the redbanded stink bug, piezodorus guildinii (westwood) (hemiptera: heteroptera: pentatomidae), is a rapidly growing pest damaging southern us agriculture. pentatomid stink bugs are known to vector bacterial, fungal, and viral plant diseases. however, bacteria associated with redbanded stink bugs and their vector potential have not yet been assessed. in this study, we 1) cultured and identified bacteria transmitted by feeding of redbanded stink bug and 2) described bacteria from guts of redband ... | 2017 | 28025221 |
| antimicrobial activity of actinobacteria isolated from the guts of subterranean termites. | subterranean termites need to minimize potentially pathogenic and competitive fungi in their environment in order to maintain colony health. we examined the ability of actinobacteria isolated from termite guts in suppressing microorganisms commonly encountered in a subterranean environment. guts from two subterranean termite species, reticulitermes flavipes (kollar) and reticulitermes tibialis banks, were extracted and plated on selective chitin media. a total of 38 actinobacteria isolates were ... | 2016 | 28028088 |
| variations and heredity in bacterial colonies. | spontaneous variation in appearance was studied in bacterial colonies of serratia marcescens f morphotype(1): (i) a defined array of non-heritable phenotype variations does appear repeatedly; (ii) the presence of colonies of different bacterial species will narrow the variability toward the typical f appearance, as if such an added environmental factor curtailed the capacity of colony morphospace; (iii) similarly the morphospace becomes reduced by random mutations leading to new, heritable morph ... | 2016 | 28042382 |
| bacterial coaggregation among the most commonly isolated bacteria from contact lens cases. | to examine the coaggregation and cohesion between the commonly isolated bacteria from contact lens cases. | 2017 | 28061510 |
| elimination and molecular identification of endophytic bacterial contaminants during in vitro propagation of bambusa balcooa. | bambusa balcooa is an economically important, multipurpose bamboo species, decidedly used in construction industry. availability of natural bamboo is depleting very rapidly due to accelerated deforestation and its unrestrained use. the large number and timely supply of saplings are the need of the hour for the restoration of bamboo stands. micropropagation, being the potent alternative for season independent rapid regeneration, is restricted in bamboo because of endophytic contamination. an in v ... | 2017 | 28063101 |
| wound and soft tissue infections of serratia marcescens in patients receiving wound care: a health care-associated outbreak. | we described a health care-associated serratia marcescens outbreak of wound and soft tissue infection lasting approximately 11 months at ankara university ibni sina hospital. after identification of s marcescens strains from the clinical and environmental samples, and their susceptibility testing to antimicrobial agents, pulsed-field gel electrophoresis (pfge) was performed to detect molecular epidemiologic relationships among these isolates. the strains which were isolated from the saline bottl ... | 2017 | 28063729 |
| effect of intermittent aeration on microbial diversity in an intermittently aerated ifas reactor treating municipal wastewater: a field study. | in the present study, the effect of three intermittent aeration (ia) cycles on treatment performance and microbial diversity was investigated in an integrated fixed film activated sludge (ifas) reactor treating municipal wastewater. the results showed that ia strategies were able to achieve efficient removal of organics and nitrogen ranging between 90 and 95% and 70 and 80%, respectively, however the phosphorus removal was found to be inversely proportional to the duration of aeration off time i ... | 2017 | 28095182 |
| rapidly eliminating pathogenic microorganisms in large air space using spraying •oh radicals. | a new method for rapidly eliminating pathogenic microorganisms in large air space using spraying •oh radicals is presented in this paper. with a physical method of strong electric-field discharge, large numbers of •oh radicals were produced by the oxygen activated particles of o2(+), o(( 1)d), o(( 3)p), etc., and the introducing reagent ho2(-). the gram-positive bacteria bacillus subtilis, the gram-negative bacteria serratia marcescens, and bacillus spores were used for the eliminating experimen ... | 2012 | 28102785 |
| antimicrobial activity, ame resistance, and a-site binding studies of anthraquinone-neomycin conjugates. | the antibacterial effects of aminoglycosides are based on their association with the a-site of bacterial rrna and interference with the translational process in the bacterial cell, causing cell death. the clinical use of aminoglycosides is complicated by resistance and side effects, some of which arise from their interactions with the human mitochondrial 12s rrna and its deafness-associated mutations, c1494u and a1555g. we report a rapid assay that allows screening of aminoglycoside compounds to ... | 2017 | 28103015 |
| draft genome sequences of pandrug-resistant serratia marcescens clinical isolates harboring blandm-1. | the draft genome sequences of two clonal, pandrug-resistant serratia marcescens clinical isolates were determined. the resistance phenotype was plasmid driven, as 14 of 17 resistance genes were present on large incfib(k), inchi2, and inca/c2 plasmids indicating a large pool of transmissible antibiotic resistance genes. | 2017 | 28104656 |
| serratia marcescens producing sme carbapenemases: an emerging resistance problem in the uk? | 2017 | 28108680 | |
| human chitotriosidase is an endo-processive enzyme. | human chitotriosidase (hcht) is involved in immune response to chitin-containing pathogens in humans. the enzyme is able to degrade chitooligosaccharides as well as crystalline chitin. the catalytic domain of hcht is connected to the carbohydrate binding module (cbm) through a flexible hinge region. in humans, two active isoforms of hcht are found-the full length enzyme and its truncated version lacking cbm and the hinge region. the active site architecture of hcht is reminiscent to that of the ... | 2017 | 28129403 |
| genomic, proteomic and biochemical analysis of the chitinolytic machinery of serratia marcescens bjl200. | the chitinolytic machinery of serratia marcescens bjl200 has been studied in detail over the last couple of decades, however, the proteome secreted by this gram-negative bacterium during growth on chitin has not been studied in depth. in addition, the genome of this most studied chitinolytic serratia strain has until now, not been sequenced. we report a draft genome sequence for s. marcescens bjl200. using label-free quantification (lfq) proteomics and a recently developed plate-method for asses ... | 2017 | 28130068 |
| phytochemistry and pharmacology of ferula persica boiss.: a review. | ferula persica, is the well-known species of the genus ferula in iran and has two varieties: persica and latisecta. they have both been extensively used in traditional medicine for a wide range of ailments. a great number of chemical compounds including sesquiterpene coumarins and polysulfides have been isolated from this plant. fresh plant materials, crude extracts and isolated components of f. persica have shown a wide spectrum of pharmacological properties including anti-pigmentation in serra ... | 2017 | 28133517 |
| [serratia marcescens outbreak in neonatal intensive care unit: guayaquil, ecuador]. | we report a serratia marcescens outbreak occurred in the nicu of a pediatric hospital in guayaquil, ecuador. nine cases of infection were detected, from which septicemia was developed in 55.5%. the index case was a newborn derived from another institution with septic arthritis caused by the outbreak strain. the infection rate was 17.6% and mortality rate was 33.3%. all isolates were resistant to aminoglycosides and susceptible to third generation cephalosporins and carbapenems. clonality analysi ... | 2016 | 28146199 |
| the risk of microbial contamination in multiple-dose preservative-free ophthalmic preparations. | multiple-dose ophthalmic preparations that do not contain preservatives carry high risks of microbial contamination. however, there are various types of hospital preparations, with different physicochemical properties. in the present study, we evaluated the association between physicochemical properties and microbial contamination in ophthalmic preparations. the investigated hospital preparations included ophthalmic preparations of physiological saline, 0.2% fluconazole, 0.5% vancomycin hydrochl ... | 2017 | 28154258 |
| serratia marcescens harboring sme-4 in brazil: a silent threat. | the intrinsic polymyxin resistance displayed by serratia marcescens makes the acquisition of carbapenemase encoding genes a worrisome event. this study report a sme-4-producing s. marcescens isolate causing septic shock in brazil. the insertion of novel resistance determinants and their consequent spread in our territory is noteworthy. | 2017 | 28159445 |
| is there a role for serratia marcescens in male infertility: an experimental study? | establishment of a male balb/c mouse model to study the role of sperm impairing s. marcescens on mouse reproductive potential. the current study can add to use of reliable animal models to provide a noteworthy evidence for the microbial cause of infertility. | 2017 | 28161359 |
| infectious disease exposures and outbreaks at a south african neonatal unit with review of neonatal outbreak epidemiology in africa. | hospitalized neonates are vulnerable to infection, with pathogen exposures occurring in utero, intrapartum, and postnatally. african neonatal units are at high risk of outbreaks owing to overcrowding, understaffing, and shared equipment. | 2017 | 28161461 |
| lepidopteran species have a variety of defence strategies against bacterial infections. | the insect immune system has versatile ways of coping with microbial insults. currently, innate immune priming has been described in several invertebrates, and the first insights into its mechanistic basis have been described. here we studied infections with two different strains of serratia marcescens bacteria in two different lepidopteran hosts. the results reveal fundamental differences between the two hosts, a well-known model organism galleria mellonella and a non-model species arctia plant ... | 2017 | 28163013 |
| oral polyphosphate suppresses bacterial collagenase production and prevents anastomotic leak due to serratia marcescens and pseudomonas aeruginosa. | the objective of this study was to determine the effect of polyphosphate on intestinal bacterial collagenase production and anastomotic leak in mice undergoing colon surgery. | 2017 | 28166091 |
| complete genome analysis of serratia marcescens rsc-14: a plant growth-promoting bacterium that alleviates cadmium stress in host plants. | serratia marcescens rsc-14 is a gram-negative bacterium that was previously isolated from the surface-sterilized roots of the cd-hyperaccumulator solanum nigrum. the strain stimulates plant growth and alleviates cd stress in host plants. to investigate the genetic basis for these traits, the complete genome of rsc-14 was obtained by single-molecule real-time sequencing. the genome of s. marcescens rsc-14 comprised a 5.12-mbp-long circular chromosome containing 4,593 predicted protein-coding gene ... | 2017 | 28187139 |
| bombyx mori serpin6 regulates prophenoloxidase activity and the expression of antimicrobial proteins. | serpins are a family of serine protease inhibitors that are found widely in insects. they play an important role in insect physiological responses, such as innate immunity and development. in this study, we obtained the bombyx mori serpin6 (bmserpin6) sequence from national center for biotechnology information (ncbi) and the silkworm genome database (silkdb). reverse transcription pcr (rt-pcr) results showed that bmserpin6 was expressed highly in hemocytes, the midgut, and the fat body. after ch ... | 2017 | 28188867 |
| high carbapenem resistance in clinical gram-negative pathogens isolated in egypt. | the emergence and spread of carbapenem-resistant gram-negative bacteria poses a serious threat to human health worldwide. currently, little is known about the molecular mechanisms underlying carbapenem resistance and their prevalence among gram-negative bacteria in egypt. in this study, we analyzed carbapenemase production in gram-negative bacteria isolated from hospitalized patients in egypt in 2014. all isolates were subjected to phenotypic and genotypic susceptibility testing for carbapenem r ... | 2017 | 28191865 |
| scrotal ulcer due to serratia marcescens. | 2017 | 28196788 | |
| isolation, identification, and characterization of foodborne pathogens isolated from egg internal contents in china. | eggs continue to be significant in terms of the world economy and human nutrition. the aim of this study was to estimate the prevalence of foodborne pathogens in a cross section of egg production types in china and to examine the virulence features of the isolated pathogens. three hundred eggs from three provinces were tested for salmonella , escherichia coli , staphylococcus aureus , and campylobacter . two eggs were positive for salmonella , one was positive for both e. coli and s. aureus , an ... | 2016 | 28221968 |
| are genital ulcers always sexually transmitted? first report of scrotal ulcer caused by serratia marcescens infection. | 2017 | 28239854 | |
| cultivable gut bacteria provide a pathway for adaptation of chrysolina herbacea to mentha aquatica volatiles. | a chemical cross-talk between plants and insects is required in order to achieve a successful co-adaptation. in response to herbivory, plants produce specific compounds, and feeding insects respond adequately7 to molecules produced by plants. here we show the role of the gut microbial community of the mint beetle chrysolina herbacea in the chemical cross-talk with mentha aquatica (or watermint). | 2017 | 28249605 |
| genome sequence of serratia marcescens msu97, a plant-associated bacterium that makes multiple antibiotics. | serratia marcescens msu97 was isolated from the guayana region of venezuela due to its ability to suppress plant-pathogenic oomycetes. here, we report the genome sequence of msu97, which produces various antibiotics, including the bacterial acetyl-coenzyme a (acetyl-coa) carboxylase inhibitor andrimid, the chlorinated macrolide oocydin a, and the red linear tripyrrole antibiotic prodigiosin. | 2017 | 28254993 |
| serratia marcescens, morganella morganii, klebsiella oxytoca related peritonitis attacks in a patient on automated peritoneal dialysis: a case report. | 2017 | 28256286 | |
| crystal structure of mbp-pigg fusion protein and the essential function of pigg in the prodigiosin biosynthetic pathway in serratia marcescens fs14. | prodigiosin, a tripyrrole red pigment is synthesized by serratia and some other microbes through a bifurcated biosynthesis pathway; mbc (4-methoxy-2,2'-bipyrrole-5-carbaldehyde) and map (2-methyl-3-n-amyl-pyrrole) are synthesized separately and then condensed by pigc to form prodigiosin. pigi, pigg and piga have been shown to be involved in the first steps of mbc biosynthesis (proline incorporation). the crystal structure of pigg was resolved to elucidate its function and mechanism. pigg, an acy ... | 2017 | 28258005 |
| carbonyl cyanide m-chlorophenylhydrazine (cccp) reverses resistance to colistin, but not to carbapenems and tigecycline in multidrug-resistant enterobacteriaceae. | background: carbapenems (car), colistin (cst), and tigecycline (tgc) alone or in combination therapy has become the last-resort antibiotics for treating infections caused by multidrug resistant (mdr) bacteria. however, resistance to these reserve antibiotics are increasingly being reported worldwide. hence, the quest to find other agents that will synergistically restore the efficacy of these antibiotics have increased. methods: sixty-three clinical enterobacteriaceae isolates comprising of kleb ... | 2017 | 28261184 |
| suppressor analysis of eepr mutant defects reveals coordinate regulation of secondary metabolites and serralysin biosynthesis by eepr and hexs. | the eepr transcription factor positively regulates secondary metabolites and tissue-damaging metalloproteases. to gain insight into mechanisms by which eepr regulates pigment and co-regulated factors, genetic suppressor analysis was performed. suppressor mutations that restored pigment to the non-pigmented ∆eepr mutant mapped to the hexs orf. mutation of hexs also restored haemolysis, swarming motility and protease production to the eepr mutant. hexs is a known direct and negative regulator of s ... | 2017 | 28270264 |
| impact of revised broad-spectrum cephalosporin clinical and laboratory standards institute breakpoints on susceptibility in enterobacteriaceae producing ampc β-lactamase. | we evaluated the impact of revised clinical and laboratory standards institute (clsi) breakpoints for broad-spectrum cephalosporins (bscs) on the susceptibilities of 1,742 isolates of enterobacter species, serratia marcescens, citrobacter freundii, and morganella morganii. the 2011 clsi criteria for cefotaxime and ceftazidime reduced the rates of susceptibility by 2.9% and 5.9%, respectively. the 2014 clsi criteria for cefepime reduced the rate of susceptibility by 13.9%, and categorized 11.8% i ... | 2017 | 28271652 |
| draft genome sequence of a multidrug-resistant nosocomial serratia marcescens strain that persisted in a hospital in kemerovo, russian federation. | serratia marcescens is a frequent cause of health care-associated infections and has led to multiple outbreaks. here, we report the draft genome of a multidrug-resistant s. marcescens strain 189 which was isolated in 2012 as a predominant clone in a neonatal hospital in kemerovo. | 2017 | 28280035 |
| characterization of two novel bacterial type a exo-chitobiose hydrolases having c-terminal 5/12-type carbohydrate-binding modules. | type a chitinases (ec 3.2.1.14), gh family 18, attack chitin ((1 → 4)-2-acetamido-2-deoxy-β-d-glucan) and chito-oligosaccharides from the reducing end to catalyze release of chitobiose (n,n'-diacetylchitobiose) via hydrolytic cleavage of n-acetyl-β-d-glucosaminide (1 → 4)-β-linkages and are thus "exo-chitobiose hydrolases." in this study, the chitinase type a from serratia marcescens (smachia) was used as a template for identifying two novel exo-chitobiose hydrolase type a enzymes, fbalchi18a an ... | 2017 | 28280871 |
| chorioamnionitis caused by serratia marcescens in a healthy pregnant woman with preterm premature rupture of membranes: a rare case report and review of the literature. | the incidence of chorioamnionitis varies widely. the highest incidence is reported in preterm deliveries. among preterm deliveries, chorioamnionitis usually occurs after preterm premature rupture of membranes (pprom). to date, only five cases of chorioamnionitis due to serratia marcescens were reported. here we present a case of a pregnant woman with chorioamnionitis due to serratia marcescens who delivered a premature neonate at 28 weeks and four days of gestation. we also conducted a review of ... | 2017 | 28283205 |
| a novel expression system for lytic polysaccharide monooxygenases. | lytic polysaccharide monooxygenases (lpmos) are key enzymatic players of lignocellulosic biomass degradation processes. as such, they have been introduced in cellulolytic cocktails for more efficient and less expensive lignocellulose saccharification. the recombinant production of lpmos in bacteria for scientific investigations using vectors typically based on the t7 and lacuv5 promoters has been hampered by low yields. reasons for this have been catabolite repression when producing the proteins ... | 2017 | 28291518 |
| characterization of batrachochytrium dendrobatidis inhibiting bacteria from amphibian populations in costa rica. | global amphibian declines and extinction events are occurring at an unprecedented rate. while several factors are responsible for declines and extinction, the fungal pathogen batrachochytrium dendrobatidis (bd) has been cited as a major constituent in these events. while the effects of this chytrid fungus have been shown to cause broad scale population declines and extinctions, certain individuals and relict populations have shown resistance. this resistance has been attributed in part to the cu ... | 2017 | 28293222 |
| scleral buckle infection by serratia species. | we describe a rare case of scleral buckle (sb) infection with serratia species. a 48-year-old male with a history of retinal detachment repair with scleral buckling presented with redness, pain, and purulent discharge in the left eye for 4 days. conjunctival erosion with exposure of the sb and scleral thinning was noted. the sb was removed and sent for culture. blood and chocolate agar grew gram-negative rod-shaped bacillus identified as serratia marcescens. on the basis of the susceptibility te ... | 2017 | 28298863 |
| umbilical infections in foals: microbiological investigation and management. | this study aims to investigate the bacteria involved in equine omphalitis and their susceptibility to antimicrobial drugs, and consequently to provide guidelines concerning the most suitable treatment protocol in accordance with the clinical, ultrasound and laboratory findings. forty foals aged between one and 30 days were evaluated in the course of this investigation. an ultrasound examination of all umbilical remnants was carried out carefully in all foals; umbilical swabs were collected for b ... | 2017 | 28314783 |
| fulminant serratia marcescens panophthalmitis. | 2017 | 28317639 | |
| [serratia infections, should we think about primary immunodeficiencies?] | chronic granulomatous disease (cgd) is a primary immunodeficiency with an incidence of 1/200,000-250,000 live births. cgd affects mainly male patients, most of the mutations being x-linked, and autosomal recessive forms occur more frequently in communities with greater numbers of consanguineous marriages. cgd is characterized by sensitivity to recurrent and severe bacterial and fungal infections, with formation of granulomas due to the inability of phagocytes to generate reactive oxygen compound ... | 2017 | 28318195 |
| packed bed reactor for degradation of simulated cyanide-containing wastewater. | the discharge of cyanide-containing effluents into the environment contaminates water bodies and soil. effective methods of treatment which can detoxify cyanide are the need of the hour. the aim of the present study is to develop a bioreactor for complete degradation of cyanide using immobilized cells of serratia marcescens rl2b. alginate-entrapped cells of s. marcescens rl2b were used for complete degradation of cyanide in a packed bed reactor (pbr). cells grown in minimal salt medium (ph 6.0) ... | 2015 | 28324513 |
| organic solvent tolerant metallo protease of novel isolate serratia marcescens ppb-26: production and characterization. | proteases are a class of enzymes that catalyze hydrolysis of peptide bonds of proteins. in this study, 221 proteolytic bacterial isolates were obtained by enrichment culture method from soils of various regions of himachal pradesh, india. from these a hyper producer of protease was screened and identified by morphological and physiological testing and by 16s rdna sequence as serratia marcescens ppb-26. statistical optimization of physiochemical parameters enhanced the protease production by 75 % ... | 2016 | 28330252 |
| polyclonal dissemination of kpc-2 in serratia marcescens, including a clone with epidemic behaviour in the nosocomial niche. | 2017 | 28336311 | |
| selenoprotein t is required for pathogenic bacteria avoidance in caenorhabditis elegans. | selenoprotein t (selenot) is an endoplasmatic reticulum (er)-associated redoxin that contains the amino acid selenocysteine (sec, u) within a cxxu motif within a thioredoxin-like fold. its precise function in multicellular organisms is not completely understood although it has been shown in mammals to be involved in ca(2+) homeostasis, antioxidant and neuroendocrine functions. here, we use the model organism c. elegans to address selenot function in a whole organism throughout its life cycle. c. ... | 2017 | 28347729 |
| long-chain 4-aminoquinolines as quorum sensing inhibitors in serratia marcescens and pseudomonas aeruginosa. | antibiotic resistance has become a serious global threat to public health; therefore, improved strategies and structurally novel antimicrobials are urgently needed to combat infectious diseases. here we report a new type of highly potent 4-aminoquinoline derivatives as quorum sensing inhibitors in serratia marcescens and pseudomonas aeruginosa, exhibiting weak bactericidal activities (minimum inhibitory concentration (mic) > 400 μm). through detailed structure-activity study, we have identified ... | 2017 | 28350449 |
| site-specific variation in gene expression from symbiodinium spp. associated with offshore and inshore porites astreoides in the lower florida keys is lost with bleaching and disease stress. | scleractinian coral are experiencing unprecedented rates of mortality due to increases in sea surface temperatures in response to global climate change. some coral species however, survive high temperature events due to a reduced susceptibility to bleaching. we investigated the relationship between bleaching susceptibility and expression of five metabolically related genes of symbiodinium spp. from the coral porites astreoides originating from an inshore and offshore reef in the florida keys. th ... | 2017 | 28355291 |
| killing of serratia marcescens biofilms with chloramphenicol. | serratia marcescens is a gram-negative bacterium with proven resistance to multiple antibiotics and causative of catheter-associated infections. bacterial colonization of catheters mainly involves the formation of biofilm. the objectives of this study were to explore the susceptibility of s. marcescens biofilms to high doses of common antibiotics and non-antimicrobial agents. biofilms formed by a clinical isolate of s. marcescens were treated with ceftriaxone, kanamycin, gentamicin, and chloramp ... | 2017 | 28356113 |
| thermodynamics of tunnel formation upon substrate binding in a processive glycoside hydrolase. | glycoside hydrolases (ghs) catalyze the hydrolysis of glycosidic bonds and are key enzymes in carbohydrate metabolism. efficient degradation of recalcitrant polysaccharides such as chitin and cellulose is accomplished due to synergistic enzyme cocktails consisting of accessory enzymes and mixtures of ghs with different modes of action and active site topologies. the substrate binding sites of chitinases and cellulases often have surface exposed aromatic amino acids and a tunnel or cleft topology ... | 2017 | 28359644 |
| fast purification method of functional lpmos from streptomyces ambofaciens by affinity adsorption. | a simple purification method by affinity adsorption was developed to obtain functional lytic polysaccharide monooxygenases (lpmos). the system allows the successful purification to homogeneity of the most characterized bacterial lpmo, cbp21 from serratia marcescens, and two lpmos from streptomyces ambofaciens, which have not been previously characterized. the first of these new lpmos, named samlpmo10b is a small enzyme (15 kda) belonging to family 10 of auxiliary activities (aa10), showing activ ... | 2017 | 28366436 |
| slpe is a calcium-dependent cytotoxic metalloprotease associated with clinical isolates of serratia marcescens. | serralysin-like proteases are found in a wide variety of bacteria. these metalloproteases are frequently implicated in virulence and are members of the widely conserved rtx-toxin family. we identified a serralysin-like protease in the genome of a clinical isolate of serratia marcescens that is highly similar to the canonical serralysin protein, prts. this gene was named serralysin-like protease e, slpe, and was found in the majority (67%) of tested clinical isolates, but was absent from most tes ... | 2017 | 28366837 |
| comparative genomic analysis reveals organization, function and evolution of ars genes in pantoea spp. | numerous genes are involved in various strategies to resist toxic arsenic (as). however, the as resistance strategy in genus pantoea is poorly understood. in this study, a comparative genome analysis of 23 pantoea genomes was conducted. two vertical genetic arsc-like genes without any contribution to as resistance were found to exist in the 23 pantoea strains. besides the two arsc-like genes, as resistance gene clusters arsrbc or arsrbch were found in 15 pantoea genomes. these ars clusters were ... | 2017 | 28377759 |
| pore-forming toxin-mediated ion dysregulation leads to death receptor-independent necroptosis of lung epithelial cells during bacterial pneumonia. | we report that pore-forming toxins (pfts) induce respiratory epithelial cell necroptosis independently of death receptor signaling during bacterial pneumonia. instead, necroptosis was activated as a result of ion dysregulation arising from membrane permeabilization. pft-induced necroptosis required rip1, rip3 and mlkl, and could be induced in the absence or inhibition of tnfr1, tnfr2 and tlr4 signaling. we detected activated mlkl in the lungs from mice and nonhuman primates experiencing serratia ... | 2017 | 28387756 |
| factors associated with infectious laryngitis: a retrospective review of 15 cases. | to identify the culturable microbes associated with infectious laryngitis and outline effective treatment strategies. | 2017 | 28397557 |
| transfer potential of plasmids conferring extended-spectrum-cephalosporin resistance in escherichia coli from poultry. | escherichia coli strains resistant to extended-spectrum cephalosporins (esc) are widely distributed in norwegian broiler production, and the majority harbor transferable inck or inci1 plasmids carrying blacmy-2 persistent occurrence in broiler farms may occur through the survival of esc-resistant e. coli strains in the farm environment, or by transfer and maintenance of resistance plasmids within a population of environmental bacteria with high survival abilities. the aim of this study was to de ... | 2017 | 28411217 |
| allodemic distribution of plasmids co-harbouring blactx-m-15/aac(6')-ib-cr/qnrb in klebsiella pneumoniae is the main source of extended-spectrum β-lactamases in uruguay's paediatric hospital. | this study aimed to describe the characteristics of clinical isolates of extended-spectrum β-lactamase (esbl)-producing enterobacteria (epe) in uruguay's paediatric hospital. | 2017 | 28419869 |
| imipenem-resistance in serratia marcescens is mediated by plasmid expression of kpc-2. | imipenem is a broad-spectrum carbapenem antibiotic with applications against severe bacterial infections. here, we describe the identification of imipenem-resistant serratia marcescens in our hospital and the role of plasmid-mediated kpc-2 expression in imipenem resistance. | 2017 | 28429335 |
| klebsiella pneumoniae carbapenemase-producing serratia marcescens outbreak in a university hospital. | 2017 | 28431850 | |
| differential sensitivity to infections and antimicrobial peptide-mediated immune response in four silkworm strains with different geographical origin. | the domesticated silkworm bombyx mori has an innate immune system, whose main effectors are the antimicrobial peptides (amps). silkworm strains are commonly grouped into four geographical types (japanese, chinese, european and tropical) and are generally characterised by a variable susceptibility to infections. to clarify the genetic and molecular mechanisms on which the different responses to infections are based, we exposed one silkworm strain for each geographical area to oral infections with ... | 2017 | 28432358 |
| serratia marcescens: an italian story. | 2017 | 28436010 | |
| production and application of a thermostable lipase from serratia marcescens in detergent formulation and biodiesel production. | in this study, extracellular lipase was produced by serratia marcescens wild type and three mutant strains. the maximum lipase activity (80 u/ml) was obtained with the smrg4 mutant strain using soybean oil. using a 2(2) factorial design, the lipase production increased 1.55-fold (124 u/ml) with 4% and 0.05% of soybean oil and triton x-100, respectively. the optimum conditions for maximum lipase activity were 50 °c and ph 8. however, the enzyme was active in a broad range of ph (6-10) and tempera ... | 2017 | 28444972 |
| evaluation of six phenotypic methods for the detection of carbapenemases in gram-negative bacteria with characterized resistance mechanisms. | we compared the performance of the modified hodge test (mht), triton hodge test (tht), carba np test (cnpt), simplified carba np test (cnpt-direct), blue-carba np test (bct), and carbapenem inactivation method (cim) for rapid and accurate carbapenemase detection. | 2017 | 28445009 |