Publications

successful maternal-foetal outcome using nitric oxide and sildenafil in pulmonary hypertension with atrial septal defect and hiv infection.	pulmonary hypertension associated with pregnancy carries a poor prognosis. we describe successful maternal-foetal outcome for a 30-year-old woman who was found to have severe pulmonary hypertension, human immunodeficiency virus (hiv) and an atrial septal defect. prior to delivery, she was managed with subcutaneous enoxaparine, sildenafil, nitric oxide, careful maintenance of a euvolemic status and antiretroviral therapy. she was planned for an elective caesarean section to reduce the risk of mat ...	2012	22252195
maternal vitamin d status and child morbidity, anemia, and growth in human immunodeficiency virus-exposed children in tanzania.	background:: vitamin d may help prevent adverse pediatric outcomes, including infectious diseases and growth failure, based on its role in immune and metabolic functions. we examined the association of maternal vitamin d status and pediatric health outcomes in children born to human immunodeficiency virus (hiv)-infected women. methods:: vitamin d status was determined in 884 hiv-infected pregnant women at 12 to 27 weeks of gestation in a trial of vitamin supplementation (not excluding vitamin d) ...	2012	22252204
the effect of changes in condom usage and antiretroviral treatment coverage on human immunodeficiency virus incidence in south africa: a model-based analysis.	this study aims to assess trends in human immunodeficiency virus (hiv) incidence in south africa, and to assess the extent to which prevention and treatment programmes have reduced hiv incidence. two models of the south african hiv epidemic, the sti (sexually transmitted infection)-hiv interaction model and the assa2003 aids and demographic model, were adapted. both models were fitted to age-specific hiv prevalence data from antenatal clinic surveys and household surveys, using a bayesian approa ...	2012	22258551
[construction, expression and immunogenicity analysis of a tat n-terminus-deleted mutant fusion protein of human immunodeficiency virus type 1].	in the study, a gene encoding tat protein n terminal 1- 21 amino acid residues-deleted mutant (tat22-101) was amplified by pcr from a full length tat gene of human immunodeficiency virus type 1, and the prokaryotic expression plasmid pet32a-tat22-101 was constructed. after identification by digestion with endonucleases and sequencing, the recombinant plasmid pet32a-tat22-101 was transformed into e. coli bl21(de3) and expressed with iptg induction. the mutant fusion protein with deleted tat n ter ...	2011	22263271
mucosal transmission of human immunodeficiency virus.	since the beginning of the aids pandemic, and following the discovery of the human immunodeficiency virus (hiv) as the etiological agent of the disease, it was clear that the virus gains access to the human host predominantly through the mucosal tissue after sexual exposure. as a consequence, the female genital tract (vaginal and cervical), as well as the rectal, penile, and oral mucosae have been extensively studied over the last thirty years towards a better understanding of - and to develop ...	2012	22264040
variable clinical presentations of classic kaposi sarcoma in turkish patients.	kaposi sarcoma (ks) is a vascular neoplasm with multicentric cutanenous and extracutaneous involvements, which was first described by moriz kaposi in 1872. since then, different epidemiological clinical and histopathological variants of this neoplasm have been identified. classic kaposi sarcoma (cks) is one of four main clinico-epidemiologiologic variants. characteristics of the disease.	2012	22514583
host and viral traits predict zoonotic spillover from mammals.	the majority of human emerging infectious diseases are zoonotic, with viruses that originate in wild mammals of particular concern (for example, hiv, ebola and sars). understanding patterns of viral diversity in wildlife and determinants of successful cross-species transmission, or spillover, are therefore key goals for pandemic surveillance programs. however, few analytical tools exist to identify which host species are likely to harbour the next human virus, or which viruses can cross species ...	2017	28636590