Publications
| Title | Abstract | Year Filter | PMID(sorted ascending) Filter |
|---|
| the use of an extract of hypericum perforatum and azadirachta indica in a neuropathic patient with advanced diabetic foot. | the successful use of an extract of hypericum flowers (hypericum perforatum) and nimh oil (azadirachta indica; hyperoil) in foot wounds with exposed bone in a patient with bilateral advanced diabetic ulcers, has been reported previously. it was hypothesised that this amelioration was linked with the improved glycaemic control and peripheral microvascular circulation. in this case report, the surprisingly successful outcome of another patient using hyperoil for infection damaged diabetic foot, wi ... | 2014 | 25378221 |
| effect of two herbal mouthwashes on gingival health of school children. | this study aimed at determining the effect of indigenously prepared neem and mango chewing stick mouthwashes on plaque and gingival indices. a sample of 105 children aged 12-15 years was randomized into three groups, namely neem, mango, and chlorhexidine mouthwash groups. all the children were examined at baseline and gingival and plaque indices were recorded. baseline scores for plaque and gingivitis were fair and moderate, respectively, in all the three groups and there existed no statisticall ... | 2014 | 25379471 |
| rhynchophorus ferrugineus midgut cell line to evaluate insecticidal potency of different plant essential oils. | cell cultures can be a potent and strong tool to evaluate the insecticidal efficiency of natural products. plant essential oils have long been used as the fragrance or curative products around the world which means that they are safer to be used in close proximity of humans and mammals. in this study, a midgut cell line, developed from rhynchophorus ferrugineus (rpw-1), was used for screening essential oils from nine different plants. assays revealed that higher cell mortality was observed at 50 ... | 2015 | 25381034 |
| limonoid and steroidal saponin from azadirachta indica. | a new limonoid, 17-(5-methoxy-2-oxofuran-3-yl)-28-deoxonimbolide (1), and a new c21 steroidal saponin, 2α,4α-dihydroxy-pregn-5-en-16-one-3α-o-d-glucopyranoside (2), together with 11 known compounds were isolated from the methanol extract of the leaves of azadirachta indica. the structures were elucidated by means of spectroscopic analysis and putative biosynthetic origins. all the compounds were evaluated for their antibacterial activities against six bacterial strains. | 2014 | 25381190 |
| nimbolide targets bcl2 and induces apoptosis in preclinical models of waldenströms macroglobulinemia. | neem leaf extract (nle) has medicinal properties, which have been attributed to its limonoid content. we identified the nle tetranorterpenoid, nimbolide, as being the key limonoid responsible for the cytotoxicity of nle in various preclinical models of human b-lymphocyte cancer. of the models tested, waldenströms macroglobulinemia (wm) cells were most sensitive to nimbolide, undergoing significant mitochondrial mediated apoptosis. notably, nimbolide toxicity was also observed in drug-resistant ( ... | 2014 | 25382610 |
| neem leaf glycoprotein prophylaxis transduces immune dependent stop signal for tumor angiogenic switch within tumor microenvironment. | we have reported that prophylactic as well as therapeutic administration of neem leaf glycoprotein (nlgp) induces significant restriction of solid tumor growth in mice. here, we investigate whether the effect of such pretreatment (25µg/mice; weekly, 4 times) benefits regulation of tumor angiogenesis, an obligate factor for tumor progression. we show that nlgp pretreatment results in vascular normalization in melanoma and carcinoma bearing mice along with downregulation of cd31, vegf and vegfr2. ... | 2014 | 25391149 |
| development of bioprocess for the production of laccase by pleurotus ostreatus mtcc 1802 using evolutionary optimization technique. | for cost effective production of laccase enzyme (benzenediol: oxygen oxidoreductase) from p. ostreatus mtcc 1802 through solid sate fermentation, physico-chemical parameters such as temperature (20-35 degrees c), incubation period (9-17 days) and substrate (neem bark and wheat bran, in various ratios, w/w) were optimized first by one parameter at time approach and then obtained optimum conditions were considered as zero level in evolutionary optimization factorial design technique. at statistica ... | 2014 | 25434106 |
| in vitro antifilarial activity of azadirachta indica aqueous extract through reactive oxygen species enhancement. | to evaluate an aqueous preparation from the azadirachta indica leaves (aea) against setaria cervi (s. cervi), a model filarial parasite. | 2014 | 25441981 |
| ethnomedicinal plants used to treat skin diseases by tharu community of district udham singh nagar, uttarakhand, india. | tharu community is the largest primitive indigenous community of the uttarakhand, india. in this article we have scientifically enumerated medicinal plants and herbal preparations used by the tharu community to treat various skin diseases, and discussed dermatological properties of these plants in the light of previous ethnomedicinal, microbiological, pharmacological, toxicological, phytochemical and clinical studies. | 2014 | 25448505 |
| brine shrimp cytotoxicity and antimalarial activity of plants traditionally used in treatment of malaria in msambweni district. | in kenya, most people use traditional medicine and medicinal plants to treat many diseases including malaria. to manage malaria, new knowledge and products are needed. traditional herbal medicine has constituted a good basis for antimalarial lead discovery and drug development. | 2015 | 25495507 |
| synthesis and characterization of zinc oxide-neem oil-chitosan bionanocomposite for food packaging application. | nano zinc oxide at different concentrations (0.1, 0.3 and 0.5%) and neem essential oil were incorporated into the chitosan polymer by solution cast method to enhance the properties of the bionanocomposite film. the functional groups, crystalline particle size, thermal stability and morphology were determined using ftir, xrd, tga and sem, respectively. the results showed that 0.5% nano zinc oxide incorporated composite film have improved tensile strength, elongation, film thickness, film transpar ... | 2015 | 25499891 |
| production of ligninolytic enzymes by white rot fungi on lignocellulosic wastes using novel pretreatments. | production of extracellular ligninolytic enzymes (laccase and polyphenol oxidase) secreted by three species of white rot fungi (pleurotus florida, p. flabellatus and p. sajor—caju) under in vivo condition was studied on two lignocellulosic substrates i.e., paddy straw and wheat straw. these lignocellulosic substrates were treated with neem (azadirachta indica) oil and ashoka (saraca indica) leaves extract. between the two lignocellulosic substrates, paddy straw pretreated with neem oil sup ... | 2014 | 25535711 |
| production of cellulolytic enzymes by pleurotus species on lignocellulosic wastes using novel pretreatments. | in the present investigation three species of pleurotus i.e. p. sajor—caju (p1), p. florida (p2) and p. flabellatus (p3) along with two lignocellulosic substrates namely paddy straw and wheat straw were selected for evaluation of production of extracellular cellulolytic enzymes. during the cultivation of three species of pleurotus under in vivo condition, the two lignocellulosic substrates were treated with plants extracts (aqueous extracts of ashoka leaves (a) and neem oil (b)), hot water ... | 2014 | 25535714 |
| in vitro thrombolytic potential of root extracts of four medicinal plants available in bangladesh. | thrombus formation inside the blood vessels obstructs blood flow through the circulatory system leading hypertension, stroke to the heart, anoxia, and so on. thrombolytic drugs are widely used for the management of cerebral venous sinus thrombosis patients, but they have certain limitations. medicinal plants and their components possessing antithrombotic activity have been reported before. however, plants that could be used for thrombolysis has not been reported so far. | 2014 | 25538351 |
| hypericum perforatum and neem oil for the management of acute skin toxicity in head and neck cancer patients undergoing radiation or chemo-radiation: a single-arm prospective observational study. | radiation dermatitis is common in patients treated with combined radiotherapy and chemotherapy for head and neck malignancies. its timely and adequate management is of uttermost importance for both oncological outcomes and global quality of life. we prospectively evaluated the role of hypericum perforatum and neem oil (holoil®; rimos srl, mirandola, italy) in the treatment of acute skin toxicity for patients undergoing radiotherapy or chemo-radiotherapy for head and neck cancer. | 2014 | 25544371 |
| ethnopharmacological assessment of medicinal plants used against livestock infections by the people living around indus river. | the present study was aimed to document detailed ethnopharmacological knowledge of medicinal plants against livestock infections of an unexplored remote region of pakistan. semistructured questionnaires were used for data collection. total 43 plants belonging to 26 families were found to be used in ethnoveterinary practices. seeds (29%) were found to be the most frequent plant part used followed by leaves (22%). ethnoveterinary recipes were mostly prepared in the form of decoction and powdering. ... | 2014 | 25544941 |
| old ingredients for a new recipe? neem cake, a low-cost botanical by-product in the fight against mosquito-borne diseases. | mosquitoes (diptera: culicidae) represent an important threat to millions of people worldwide, since they act as vectors for important pathogens, such as malaria, yellow fever, dengue and west nile. control programmes mainly rely on chemical treatments against larvae, indoor residual spraying and insecticide-treated bed nets. in recent years, huge efforts have been carried out to propose new eco-friendly alternatives, with a special focus on the evaluation of plant-borne mosquitocidal compounds. ... | 2015 | 25563612 |
| hypoglycemic effect of combination of azadirachta indica a. juss. and gynura procumbens (lour.) merr. ethanolic extracts standardized by rutin and quercetin in alloxan-induced hyperglycemic rats. | exploration of plant combinations could be an alternative approach for diabetes treatment. the aim of this study is to evaluate the hypoglycemic effect of combination of a. indica and g. procumbens ethanolic extracts in alloxan-induced diabetic rats. | 2014 | 25671197 |
| chemopreventive effects of azadirachta indica on cancer marker indices and ultrastructural changes during 1,2-dimethylhydrazine-induced colon carcinogenesis in rats. | the present study elucidated the prospective of azadirachta indica supplementation, if any, in affording chemoprevention by modulating the altered cancer markers and ultrastructural changes in dmh-induced colorectal carcinogenesis in rats. the rats were segregated into four groups viz., normal control, dmh treated, a. indica treated, and dmh+ai treated. initiation and induction of colon carcinogenesis were achieved through weekly subcutaneous injections of dmh (30 mg/kg body weight) for both 10 ... | 2015 | 25697750 |
| review on molecular and chemopreventive potential of nimbolide in cancer. | cancer is the most dreaded disease in human and also major health problem worldwide. despite its high occurrence, the exact molecular mechanisms of the development and progression are not fully understood. the existing cancer therapy based on allopathic medicine is expensive, exhibits side effects; and may also alter the normal functioning of genes. thus, a non-toxic and effective mode of treatment is needed to control cancer development and progression. some medicinal plants offer a safe, effec ... | 2014 | 25705153 |
| in vitro and in vivo evaluation of anti-leishmanial and immunomodulatory activity of neem leaf extract in leishmania donovani infection. | the toxicity and emergence of resistance to available chemical drugs against visceral leishmaniasis is evoking to explore herbal treatment. one such attempt with the neem is being reported here. the current study is primarily focused to evaluate the anti-leishmanial effects of neem leaf extracts. among which, ethyl acetate fraction (eaf) alone was found to exhibit leishmanicidal effect validated through cytotoxicity assay and estimated its ic₅₀ to be 52.4 µg/ml on the promastigote stage. propidi ... | 2015 | 25747203 |
| a comprehensive study on apoptosis induction by azadirachtin in spodoptera frugiperda cultured cell line sf9. | the induction of apoptosis by azadirachtin, a well-known botanical tetranortriterpenoid isolated from the neem tree (azadirachta indica a. juss) and other members of the meliaceae, was investigated in spodoptera frugiperda cultured cell line (sf9). morphological changes in sf9 cells treated by various concentrations of azadirachtin were observed at different times under light microscopy. morphological and biochemical analysis indicated that sf9 cells treated by 1.5 μg/ml azadirachtin showed typi ... | 2015 | 25828604 |
| aqueous extract of some indigenous medicinal plants inhibits glycation at multiple stages and protects erythrocytes from oxidative damage-an in vitro study. | azadirachta indica, emblica officinalis, syzygium cumini and terminalia bellirica are common in indian system of traditional medicine for the prevention of diabetes and its complications. the aim of the present study was to comprehensively and comparatively investigate the antiglycation potential of these plant extracts at multiple stages and their possible protective effect against glycated albumin mediated toxicity to erythrocytes. antiglycation activities of these plant extracts was measured ... | 2015 | 25829572 |
| in vitro and in vivo activity of essential oils against major postharvest pathogens of kinnow (citrus nobilis × c. deliciosa) mandarin. | the present study envisages the influence of essential oils namely lemon grass, eucalyptus, clove and neem on kinnow mandarin with the objective to combat major post harvest diseases and to prolong its availability for longer time in the season. for this, in vitro and in vivo studies were conducted. poisoned food technique was used for in vitro studies, and for in vivo studies, kinnow fruit were pre-inoculated with pathogens (penicillium digitatum and p. italicum), treated with different essenti ... | 2015 | 25829604 |
| bioactivity of six plant extracts on adults of demotispa neivai (coleoptera: chrysomelidae). | demotispa neivai bondar (coleoptera: chrysomelidae) damage oil palm fruits, which makes it necessary to develop products to control this insect. the mortality, repellency, and antifeeding effects on adults of d. neivai of six plant extracts of azadirachta indica a. juss. (sapindales: meliaceae), ricinus communis (l.) (malpighiaes: euphorbiaceae), citrus sinensis oesbek (sapindales: rutaceae), nicotiana tabacum (l.) (slanales: solanaceae), capsicum annuum (l.) (solanales: solanaceae), and artemis ... | 2015 | 25843587 |
| azadirachtin, a neem-derived biopesticide, impairs behavioral and hematological parameters in carp (cyprinus carpio). | azadirachtin (aza) is a promisor biopesticide used in organic production and aquaculture. although this compound is apparently safe, there is evidence that it may have deleterious effects on fish. behavioral and hematological tests are grouped into a set of parameters that may predict potential toxicity of chemical compounds. here, we investigate the effects of aza, in the commercial formulation neenmax(™) , on carp (cyprinus carpio) by defining lc50 (96 h), and testing behavioral and hematologi ... | 2016 | 25847134 |
| cytoprotective and anti-secretory effects of azadiradione isolated from the seeds of azadirachta indica (neem) on gastric ulcers in rat models. | azadirachta indica is well known medicinal plant mentioned in ancient herbal texts. it has been extensively used in ayurvedic, unani and homoeopathic medicine and has become a luminary of modern medicine. as part of our drug discovery program we isolated azadiradione from the ethanolic extract of seeds of a. indica and evaluated for in-vivo antiulcer activity in cold restraint induced gastric ulcer model, aspirin induced gastric ulcer model, alcohol induced gastric ulcers model and pyloric ligat ... | 2015 | 25851068 |
| organic neem compounds inhibit soft-rot fungal growth and improve the strength of anthracite bricks bound with collagen and lignin for use in iron foundry cupolas. | to examine organic neem compounds for their effective growth inhibition of saprotrophic soft-rot fungi on anthracite bricks bound with collagen and lignin for use in iron foundry cupolas as an alternative fuel source. | 2015 | 25857444 |
| apoptosis mediated leishmanicidal activity of azadirachta indica bioactive fractions is accompanied by th1 immunostimulatory potential and therapeutic cure in vivo. | exploration of immunomodulatory antileishmanials of plant origin is now being strongly recommended to overcome the immune suppression evident during visceral leishmaniasis (vl) and high cost and toxicity associated with conventional chemotherapeutics. in accordance, we assessed the in vitro and in vivo antileishmanial and immunomodulatory potential of ethanolic fractions of azadirachta indica leaves (ale) and seeds (ase). | 2015 | 25884649 |
| impact of repeated neemazal-treated blood meals on the fitness of anopheles stephensi mosquitoes. | herbal remedies are widely used in many malaria endemic countries to treat patients, in particular in the absence of anti-malarial drugs and in some settings to prevent the disease. herbal medicines may be specifically designed for prophylaxis and/or for blocking malaria transmission to benefit both, the individual consumer and the community at large. neem represents a good candidate for this purpose due to its inhibitory effects on the parasite stages that cause the clinical manifestations of m ... | 2015 | 25884799 |
| efficacy of neem chippings for mosquito larval control under field conditions. | an in depth understanding of mosquito breeding biology and factors regulating population sizes is fundamental for vector population control. this paper presents results from a survey of mosquito breeding habitats and the efficacy of neem chippings as a potential larvicide that can be integrated in mosquito control on nyabondo plateau in western kenya. | 2015 | 25888120 |
| complementary and alternative medicine for psoriasis: what the dermatologist needs to know. | complementary and alternative medicine (cam) use is common among patients with psoriasis. cam modalities include traditional chinese medicine (tcm), herbal therapies, dietary supplements, climatotherapy, and mind/body interventions. in this review, evidence from clinical trials investigating the efficacy of cam for psoriasis is reviewed. there is a large amount of evidence from controlled trials that have shown that the combination of tcm with traditional therapies for psoriasis is more efficaci ... | 2015 | 25904522 |
| yield loss assessment due to alternaria blight and its management in linseed. | field experiments were conducted during 2010-11 and 2011-12 to assess the yield losses due to alternaria blight disease caused by alternaria lini and a. linicola in recently released cultivars and their management with the integration of trichoderma viride, fungicides and plant extract. disease severity on leaves varied from 41.07% (parvati) to 65.01% (chambal) while bud damage per cent ranged between 23.56% (shekhar) to 46.12% (t-397), respectively in different cultivars. maximum yield loss of ... | 2014 | 25911838 |
| induction of cell cycle arrest, dna damage, and apoptosis by nimbolide in human renal cell carcinoma cells. | nimbolide is a tetranortriterpenoid isolated from the leaves and flowers of azadirachta indica which has been shown to exhibit anticancer, antioxidant, anti-inflammatory, and anti-invasive properties in a variety of cancer cells. however, the anti-tumor effect on human renal cell carcinoma (rcc) cells is unknown. in this study, we found that nimbolide treatment had a cytotoxic effect on 786-o and a-498 rcc cells in a dose-dependent manner. according to flow cytometric analysis, nimbolide treatme ... | 2015 | 25916210 |
| comparative anti-inflammatory effects of anti-arthritic herbal medicines and ibuprofen. | non-steroidal anti-inflammatory drugs (nsaids), such as ibuprofen, are widely used over-the-counter drugs to treat arthritis, but they are often associated with side effects. herbal medicines have been used to treat various diseases such as arthritis, but the scientific profiles are not well understood. in this study, we examined, in comparison with ibuprofen, the inhibitory effects on various inflammatory markers of the most commonly used herbal medicines to treat arthritis, boswellia (boswelli ... | 2014 | 25918809 |
| chemical prospection of important ayurvedic plant tinospora cordifolia by uplc-dad-esi-qtof-ms/ms and nmr. | a rapid, sensitive, and accurate ultra-performance liquid chromatography coupled with mass spectrometric method (uplc-ms) was developed and validated for simultaneous determination of four bioactive compounds, syringin (3), cordifolioside a (4), magnoflorine (6) and tinocordiside (10) in the stem of tinospora cordifolia. the analysis was performed using an acquity c18 column and gradient elution of 0.05% formic acid in water and acetonitrile at a detection wavelength of 267 nm in 5 min. a high c ... | 2015 | 25920217 |
| antifertility activity of medicinal plants. | the aim of this review was to provide a comprehensive summary of medicinal plants used as antifertility agents in females throughout the world by various tribes and ethnic groups. we undertook an extensive bibliographic review by analyzing classical text books and peer reviewed papers, and further consulting well accepted worldwide scientific databases. we performed central, embase, and pubmed searches using terms such as "antifertility", "anti-implantation", "antiovulation", and "antispermatoge ... | 2015 | 25921562 |
| a novel biopesticide ponneem to control human vector mosquitoes anopheles stephensi l. and culex quinquefasciatus say. | organophosphate pesticides are widely used in vector mosquito management and agricultural pest management. these chemicals enter into natural water bodies and soil and cause hazards to the environment. the objective of this study was to prepare a natural pesticide which will not harm the environment and yet control vector mosquitoes. ponneem, a novel biopesticide, patented and prepared from the oils of azadirachta indica and pongamia glabra, was tested against anopheles stephensi and culex quinq ... | 2015 | 25929457 |
| repellent efficacy of deet, mygga, neem (azedirachta indica) oil and chinaberry (melia azedarach) oil against anopheles arabiensis, the principal malaria vector in ethiopia. | in ethiopia, anopheles arabiensis is the main vector responsible for the transmission of malaria in the country and its control mainly involves application of indoor residual spraying (irs) and use of insecticide-treated bed nets (itns). | 2015 | 25935845 |
| process optimization and kinetics of biodiesel production from neem oil using copper doped zinc oxide heterogeneous nanocatalyst. | heterogeneous nanocatalyst has become the choice of researchers for better transesterification of vegetable oils to biodiesel. in the present study, transesterification reaction was optimized and kinetics was studied for biodiesel production from neem oil using czo nanocatalyst. the highly porous and non-uniform surface of the czo nanocatalyst was confirmed by afm analysis, which leads to the aggregation of czo nanoparticles in the form of multi layered nanostructures. the 97.18% biodiesel yield ... | 2015 | 25958133 |
| head louse control by suffocation due to blocking their oxygen uptake. | the present study shows that head lice (pediculus humanus capitis) are killed by suffocation when submersed into the anti-louse shampoo licener®, which contains a mild shampoo component and an extract of neem seeds after their oil components had been pressed off. it is shown that the inner tracheal system becomes completely filled by the very fluid product. within 3-10 min, oxygen uptake is prohibited and death of all thus treated lice stages occurred. | 2015 | 25990060 |
| content of trace elements and chromium speciation in neem powder and tea infusions. | total concentrations of selected trace elements in neem powder and in neem tea were determined by inductively coupled plasma mass spectrometry (icp-ms). the data revealed that despite high total concentrations of the potentially toxic elements al and ni in neem powder, their amounts dissolved in neem tea were low. total concentrations of the other toxic elements pb, as and cd were also very low and do not represent a health hazard. in contrast, total concentrations of the essential elements fe, ... | 2015 | 26004899 |
| azadirachta indica: a herbal panacea in dentistry - an update. | azadirachta indica commonly known as neem, is an evergreen tree. since time immemorial it has been used by indian people for treatment of various diseases due to its medicinal properties. it possesses anti-bacterial, anti-cariogenic, anti-helminthic, anti-diabetic, anti-oxidant, astringent, anti-viral, cytotoxic, and anti-inflammatory activity. nimbidin, azadirachtin and nimbinin are active compounds present in neem which are responsible for antibacterial activity. neem bark is used as an active ... | 2017 | 26009692 |
| toxicity of some plant extracts against vector of lymphatic filariasis, culex pipiens. | many insecticides are generally used as larvicides to control culex pipiens, vector of lymphatic filariasis. this study was undertaken to evaluate the larvicidal activity of some potential larvicidal plants extracts against c. pipiens larvae. the toxic effects of both ethanolic and petroleum ether plant extracts were evaluated under laboratory conditions against 3rd instar larvae of c. pipiens. forty ethanolic and petroleum ether extracts of 10 plants namely echinochloa stagninum, phragmites aus ... | 2015 | 26012233 |
| comparative analysis of biosynthesised and chemosynthesised silver nanoparticles with special reference to their antibacterial activity against pathogens. | the present study reports the synthesis of silver nanoparticles (agnps) using both biological and chemical routes to find out the best method for control of their size and activity. the fungal agent (fusarium oxysporum) and the plant (azadirachta indica) were found to be the best source for agnps synthesis. both biosynthesis and chemosynthesis were achieved by challenging filtrate with agno3 (1 mm) solution. the synthesised nanoparticles were characterised by ultraviolet-visible spectroscopy, fo ... | 2015 | 26023154 |
| determination of lead isotopes in a new greenland deep ice core at the sub-picogram per gram level by thermal ionization mass spectrometry using an improved decontamination method. | an improved decontamination method and ultraclean analytical procedures have been developed to minimize pb contamination of processed glacial ice cores and to achieve reliable determination of pb isotopes in north greenland eemian ice drilling (neem) deep ice core sections with concentrations at the sub-picogram per gram level. a pl-7 (fuso chemical) silica-gel activator has replaced the previously used colloidal silica activator produced by merck and has been shown to provide sufficiently enhan ... | 2015 | 26048818 |
| isolation and evaluation of anticancer efficacy of stigmasterol in a mouse model of dmba-induced skin carcinoma. | stigmasterol (99.9% pure) was isolated from azadirachta indica and its chemopreventive effect on 7,12-dimethylbenz[a]anthracene (dmba)-induced skin cancer was investigated in swiss albino mice. skin tumors were induced by topical application of dmba and promoted by croton oil. to assess the chemopreventive potential of stigmasterol, it was orally administered at a concentration of 200 mg/kg and 400 mg/kg three times weekly for 16 weeks. reduction in tumor size and cumulative number of papillomas ... | 2015 | 26060396 |
| protein-protein and dna-protein interactions mediate induction of defense genes by fruit extract of azadirachta indica a. juss. in solanum lycopersicum l. | the present work demonstrates that induction of defense-related genes in tomato by neem extract was mediated by protein-protein and dna-protein interactions. the induction of elicitor-mediated defense responses in plants is known, but the molecular mechanisms underlying its induction are not well studied. in the present study, third node leaf from the base of aseptically raised tomato plants was treated with aqueous fruit extracts of azadirachta indica a. juss. (neem). samples were collected fro ... | 2015 | 26063614 |
| neem (azadirachta indica a. juss) oil to tackle enteropathogenic escherichia coli. | neem (azadirachta indica a. juss) oil (no) was assayed against forty-eight isolates of escherichia coli by standardised disc diffusion test and microdilution test. by molecular biology characterization, fourteen isolates resulted in diarrheagenic e. coli with sixteen primer pairs that specifically amplify unique sequences of virulence genes and of 16s rrna. the no showed biological activity against all isolates. the bacterial growth inhibition zone by disc diffusion method (100 µl no) ranged bet ... | 2015 | 26064900 |
| effects of azardirachta indica on vascular endothelial growth factor and cytokines in diabetic deep wound. | a chronic, unhealed diabetic wound is one of the severe complications of diabetes mellitus. azadirachta indica has been reported to have antidiabetic and antiapoptotic properties. the present work incorporates the healing potential of 50 % ethanol a. indica leaves extract against deep surgical wounds in streptozotocin-induced mild diabetic rats. a. indica leaves extract (500 mg/kg) was administered orally, once daily for ten days. serum glucose, cholesterol, and triglycerides as well as body wei ... | 2015 | 26069952 |
| neem: unusually versatile plant genus azadirachta with many useful and so far insufficiently exploited properties for agriculture, medicine, and industry. | neem plants (rutales: meliaceae) are well known for their multitude of human benefits in various fields. specifically well investigated are the indian neem tree azadirachta indica a. juss., the thai neem a. siamensis val., the originally malaysian/philippinean neem a. excelsa (jack) and, as a close relative, the persian lilac, melia azedarach. the major and most active natural products are azadirachtin, salannin, nimbin and marrangin from azadirachta species, and azadirachtin analogues like meli ... | 2014 | 26084100 |
| cytotoxic activity of macrosolen parasiticus (l.) danser on the growth of breast cancer cell line (mcf-7). | macrosolen parasiticus (l.) danser belonging to loranthaceaea (mistletoe family) is a parasitic plant that grows on different host plants such as mango, jack fruit, peepal, neem tree, etc., this study was aimed to investigate the anti-cancer activity of methanolic and aqueous extract of stem of m. parasiticus. | 2015 | 26109761 |
| an ethnobotanical survey of antidiabetic plants used by hausa-fulani tribes in sokoto, northwest nigeria. | sokoto is known for its diverse traditional medicinal wealth and international market of traditional medicines in africa. however, information of the folk knowledge, especially for the treatment of diabetes, is not documented. | 2015 | 26117532 |
| silver nanoparticles embedded mesoporous sio₂ nanosphere: an effective anticandidal agent against candida albicans 077. | candida albicans is a diploid fungus that causes common infections such as denture stomatitis, thrush, urinary tract infections, etc. immunocompromised patients can become severely infected by this fungus. development of an effective anticandidal agent against this pathogenic fungus, therefore, will be very useful for practical application. in this work, ag-embedded mesoporous silica nanoparticles (msio2@agnps) have successfully been synthesized and their anticandidal activities against c. albic ... | 2015 | 26119911 |
| biogenic synthesis of fluorescent carbon dots at ambient temperature using azadirachta indica (neem) gum. | synthesis of fluorescent carbon dots (cds) from various carbonaceous materials apparently has acquired lots of interest amongst researchers as the corollary of the properties of cds; which are subsequently getting unveiled. in this study we report the use of azadirachta indica (neem) gum as a novel natural pre-cursor for synthesis of cds at room temperature. water soluble cds of around 5-8 nm were obtained after treatment of the gum with ethanol and naoh. these cds exhibited green fluorescence i ... | 2015 | 26123675 |
| biosynthesized silver nanoparticles performing as biogenic sers-nanotags for investigation of c26 colon carcinoma cells. | in this work, two classes of silver nanoparticles (agnps) were biosynthesized with the goal to assess their reliability in vitro as surface-enhanced raman scattering (sers) nanotags. mycosynthesized silver nanoparticles (magnps) and phytosynthesized silver nanoparticles (pagnps) were produced through environmentally friendly procedures by reduction of silver nitrate with fusarium oxysporum cell filtrate and azadirachta indica extract, respectively. two cell lines, namely c26 murine colon carcino ... | 2015 | 26123850 |
| effect of combined herbal feed additives on methane, total gas production and rumen fermentation. | the present study was to evaluate effect of herbal feed additives on methane and total gas production during the rumen fermentation for environment and animal health concern. different parts of the five medicinal plants were selected such as leaf and small stems of ocimum sanctum (tulsi), roots of curcuma longa (haldi), fruits of emblica officinalis (amla), leaves of azadirachta indica (neem) and leaves and small stem of clerodendrum phlomidis (arni) for our study. addition of different herbal a ... | 2015 | 26124571 |
| chemopreventive effect of methanolic extract of azadirachta indica on experimental trypanosoma brucei induced oxidative stress in dogs. | the medicinal properties of azadirachta indica have been harnessed for many years in the treatment of many diseases in both humans and animals. | 2017 | 26130936 |
| report: in vivo anticoccidial effects of azadirachta indica and carica papaya l. with salinomycin drug as a dietary feed supplement in broiler chicks. | a total of thirty suspected broiler chicks were screened for coccidiosis, of them 25 chicks were found to be infected with coccidiosis viz. eimeria tenella (15) eimeria maxima (5) eimeria necatrix (6) and eimeria mitis (4). the anticoccidial efficacy of azadirachta indica and carica papaya with salinomycin as a dietary feed supplement on the representative e. tenella (25 x 10³ oocyst) infection challenged in broiler chicks was studied in six groups for the period of six weeks. a. indica and c. p ... | 2015 | 26142532 |
| identification and antifeedant activities of limonoids from azadirachta indica. | four new limonoids, azadiraindins a-d (1-4, resp.), together with seven known analogs, were isolated from the meoh extract of azadirachta indica. the structures of 1-4 were elucidated by nmr and ms spectroscopic analyses, and the relative configuration of 1 was determined by single-crystal x-ray crystallography. the compounds isolated in comparatively large amount were evaluated for their antifeedant activities against plutella xylostella; the antifeedant rate of 10 was 90.6% and the corrected m ... | 2015 | 26172324 |
| phytoremediation potential of chromium-containing tannery effluent-contaminated soil by native indian timber-yielding tree species. | twenty-six native indian tree species that are used for the enhanced tree cover program of the forest department (government of tamilnadu, india) were screened for phytoremediation of tannery effluent-contaminated soil containing high chromium content. out of 26 tree species tested, 10 timber-yielding tree species were selected for further phytoremediation monitoring. after a series of treatments with tannery effluent sludge, the chromium content was measured in the plant parts. the saplings of ... | 2016 | 26177918 |
| effect of neem (azadirachta indica) on the survival of escherichia coli o157:h7 in dairy manure. | escherichia coli o157:h7 (eco157) shed in cattle manure can survive for extended periods of time and intervention strategies to control this pathogen at the source are critical as produce crops are often grown in proximity to animal raising operations. this study evaluated whether neem (azadirachta indica), known for its antimicrobial and insecticidal properties, can be used to amend manure to control eco157. the influence of neem materials (leaf, bark, and oil) on the survival of an apple juice ... | 2015 | 26184255 |
| ethnomedicinal survey of plants used in the treatment of malaria in southern nigeria. | malaria is one of the most severe public health problems worldwide. it is a leading cause of death and disease in many developing countries, where young children and pregnant women are the groups most affected. spread of multidrug-resistant strains of plasmodium and the adverse side effects of the existing anti-malarial drugs have necessitated the search for novel, well tolerated and more efficient antimalarial drugs. this ethnomedicinal study surveyed the different types of medicinal plants use ... | 2015 | 26187278 |
| sulfonoquinovosyl diacylglyceride selectively targets acute lymphoblastic leukemia cells and exerts potent anti-leukemic effects in vivo. | dna topoisomerase ii inhibitors e.g. doxorubicin and etoposide are currently used in the chemotherapy for acute lymphoblastic leukemia (all). these inhibitors have serious side effects during the chemotherapy e.g. cardiotoxicity and secondary malignancies. in this study we show that sulfonoquinovosyl diacylglyceride (sqdg) isolated from azadirachta indica exerts potent anti-all activity both in vitro and in vivo in nude mice and it synergizes with doxorubicin and etoposide. sqdg selectively targ ... | 2015 | 26189912 |
| metals bioaccumulation mechanism in neem bark. | the aim of this work was to define the bioaccumulation mechanism of metals onto the non-living biomaterial prepared from an extensively available plant bark biomass of neem (azadirachta indica). based on maximum ultimate fixation capacities (mmol/g) of the product, metals ions could be arranged as hg(2+) < cd(2+) < pb(2+) ≅ cu(2+). surface properties of the biomaterial were characterized by x-ray photoelectron spectroscopy and x-ray diffraction techniques for their sorption mechanism. whewellite ... | 2015 | 26193837 |
| effect of neem oil and haridra on non-healing wounds. | in ayurveda, vrana (wound) has stated as tissue destruction and discoloration of viable tissue due to various etiology. in sushruta samhita, sushruta described vrana as a main subject. most commonly vrana can be classified into shuddha and dushta vrana (chronic wound/nonhealing ulcers). among the various drugs mentioned for dushta vrana, two of them, neem (azadirechta indica a. juss) oil and haridra (curcuma longa linn.) powder are selected for their wide spectrum action on wound. | 2017 | 26195902 |
| acute renal failure induced by chinese herbal medication in nigeria. | traditional herbal medicine is a global phenomenon especially in the resource poor economy where only the very rich can access orthodox care. these herbal products are associated with complications such as acute renal failure and liver damage with a high incidence of mortalities and morbidities. acute renal failure from the use of herbal remedies is said to account for about 30-35% of all cases of acute renal failure in africa. most of the herbal medications are not usually identified, but some ... | 2015 | 26199625 |
| development of shampoo, soap and ointment formulated by green synthesised silver nanoparticles functionalised with antimicrobial plants oils in veterinary dermatology: treatment and prevention strategies. | many scientists have focused their research on the role of nanotechnology for the control of human pathogens, but there are also many topical pathogens present in animals, which infect animals and transfer to humans. topical therapy is extremely important for the management of dermatological condition in animals. therefore, the present study aims to evaluate the efficacy of biogenic silver nanoparticles (agnps) in combination with herbal oils against animal skin infections which may be responsib ... | 2015 | 26224344 |
| production of limonoids with insect antifeedant activity in a two-stage bioreactor process with cell suspension culture of azadirachta indica. | neem tree (azadirachta indica) cell suspension culture is an alternative for the production of limonoids for insect control that overcomes limitations related to the supply of neem seeds. to establish conditions for cell growth and azadiracthin-related limonoid production, the effect of different sucrose concentrations, nitrate and phosphate in murashige and skoog (ms) medium, and the addition of one precursor and three elicitors was evaluated in shake flasks. the process was scaled up to a 3-l ... | 2015 | 26234433 |
| facile green fabrication of nanostructure zno plates, bullets, flower, prismatic tip, closed pine cone: their antibacterial, antioxidant, photoluminescent and photocatalytic properties. | green synthesis of multifunctional zinc oxide nanoparticles (nps) with a variety of morphologies were achieved by low temperature solution combustion route employing neem (azadirachta indica) extract as fuel. the nanoparticles were characterized by pxrd, ftir, xps, raman and uv-visible spectroscopic studies. the morphologies were studied by sem and tem analysis. the nps were subjected for photoluminescence, photocatalytic, antibacterial and antioxidant activity studies. pxrd pattern confirmed th ... | 2016 | 26241826 |
| five new guaiane sesquiterpenes from the endophytic fungus xylaria sp. ym 311647 of azadirachta indica. | five new guaiane sesquiterpenes, 1-5, were isolated from the culture broth of the endophytic fungus xylaria sp. ym 311647, isolated from azadirachta indica a. juss. the structures of these compounds were elucidated on the basis of spectroscopic analyses, and their inhibitory activities against five pathogenic fungi were evaluated. all guaiane sesquiterpenes showed moderate or weak antifungal activities in a broth microdilution assay. | 2015 | 26265580 |
| antiviral phytochemicals identification from azadirachta indica leaves against hcv ns3 protease: an in silico approach. | hepatitis c virus (hcv) is a major health problem across the world affecting the people of all age groups. it is the main cause of hepatitis and at chronic stage causes liver cirrhosis and hepatocellular carcinoma. various therapeutics are made against hcv but still there is a need to find out potential therapeutics to combat the virus. the goal of this study is to identify the phytochemicals of azadirachta indica leaves having antiviral activity against hcv ns3 protease through molecular dockin ... | 2016 | 26274064 |
| small molecule trkb agonist deoxygedunin protects nigrostriatal dopaminergic neurons from 6-ohda and mptp induced neurotoxicity in rodents. | dopaminergic neurons loss in the substantia nigra (sn) and dopamine (da) content loss in the striatum correlate well with disease severity in parkinson's disease (pd). brain-derived neurotrophic factor (bdnf) is a member of neurotrophin family and is necessary for the survival and development of da neurons in the sn. deficits in bdnf/trkb receptors signaling contribute to the dysfunction of pd. deoxygedunin, a derivative of gedunin produced from indian neem tree, binds trkb receptor and activate ... | 2015 | 26282118 |
| biofilm forming capacity of enterococcus faecalis on gutta-percha points treated with four disinfectants using confocal scanning laser microscope: an in vitro study. | the aim of this study was to evaluate and compare the in vitro biofilm forming capacity of enterococcus faecalis on gutta-percha points disinfected with four disinfectants. | 2017 | 26288622 |
| comprehensive analyses of genomes, transcriptomes and metabolites of neem tree. | neem (azadirachta indica a. juss) is one of the most versatile tropical evergreen tree species known in india since the vedic period (1500 bc-600 bc). neem tree is a rich source of limonoids, having a wide spectrum of activity against insect pests and microbial pathogens. complex tetranortriterpenoids such as azadirachtin, salanin and nimbin are the major active principles isolated from neem seed. absolutely nothing is known about the biochemical pathways of these metabolites in neem tree. to id ... | 2015 | 26290780 |
| steroidal glycoalkaloids: chemical defence of edible african nightshades against the tomato red spider mite, tetranychus evansi (acari: tetranychidae). | tetranychus evansi is an invasive pest of solanaceous crops in africa, and in the field it differentially attacks edible african nightshades. the chemical basis for the differential attack on these plant species is largely unknown. using bioassays and chemical analysis, we investigated the differential bioactivity of leaf extracts of three edible african nightshade species, solanum sarrachoides, s. scabrum and s. villosum, on adult t. evansi females. | 2016 | 26299255 |
| traditional plants used for the treatment of diabetes mellitus in sursagar constituency, jodhpur, rajasthan - an ethnomedicinal survey. | in jodhpur, large number of people suffering with non-insulin dependent diabetes mellitus (type 2 diabetes). they are using medicinal plants along with modern medicine for the management of diabetes. the aim of this work is to document the anti-diabetic plants and determine the most relevant anti-diabetic plant species using the disease consensus index. | 2015 | 26325432 |
| triterpenoid profiling and functional characterization of the initial genes involved in isoprenoid biosynthesis in neem (azadirachta indica). | neem tree (azadirachta indica) is one of the richest sources of skeletally diverse triterpenoids and they are well-known for their broad-spectrum pharmacological and insecticidal properties. however, the abundance of neem triterpenoids varies among the tissues. here, we delineate quantitative profiling of fifteen major triterpenoids across various tissues including developmental stages of kernel and pericarp, flower, leaf, stem and bark using uplc-esi(+)-hrms based profiling. transcriptome analy ... | 2015 | 26335498 |
| molecular docking based screening of neem-derived compounds with the ns1 protein of influenza virus. | different strains of influenza virus are affecting a large number of people worldwide to combat with influenza virus destruction, numerous synthetic antiviral medicines are available for influenza virus in the market. but still there was a need for the development of drug which will target all the strains of influenza virus. for this purpose conserved residues within the influenza virus ns1 protein have been found by aligning all the available sequences of existing strains from the national cent ... | 2015 | 26339153 |
| gedunin abrogates aldose reductase, pi3k/akt/mtor, and nf-κb signaling pathways to inhibit angiogenesis in a hamster model of oral carcinogenesis. | aberrant activation of oncogenic signaling pathways plays a central role in tumor development and progression. the aim of this present study was to investigate the chemopreventive effects of the neem limonoid gedunin in the hamster model of oral cancer based on its ability to modulate aldose reductase (ar), phosphatidyl inositol-3-kinase (pi3k)/akt, and nuclear factor kappa b (nf-κb) pathways to block angiogenesis. administration of gedunin suppressed the development of hbp carcinomas by inhibit ... | 2016 | 26342697 |
| management of root-knot nematode (meloidogyne incognita) in bottle gourd using different botanicals in pots. | a pot experiment was conducted to study the efficacy of different botanicals in varying doses for management of root-knot nematode, m. incognita in bottle gourd. the results exhibited that madar (calotropis procera) and neem (azadirachta indica) leaves application proved to be more effective in improving plant growth characters and reducing root-knot index and final nematode population. among the doses tested, higher dose of 1.5 % (w/w) was more effective than lower ones. | 2015 | 26345048 |
| antimicrobial biosynthetic potential and genetic diversity of endophytic actinomycetes associated with medicinal plants. | endophytic actinomycetes are one of the primary groups that share symbiotic relationships with medicinal plants and are key reservoir of biologically active compounds. in this study, six selective medicinal plants were targeted for the first time for endophytic actinomycetes isolation from gibbon wild life sanctuary, assam, india, during winter and summer and 76 isolates were obtained. the isolates were found to be prevalent in roots followed by stem and leaves. 16s rrna gene sequence analysis r ... | 2015 | 26347302 |
| fourier transform infrared spectroscopic studies on modulation of n-nitrosodiethylamine-induced hepatocarcinogenesis by azadirachta indica. | fourier transform infrared spectroscopy was employed in the present study to obtain information about the molecular composition of hepatic tumor versus hepatic tissue. a hepatic cancer model was developed by administering n-nitrosodiethylamine (ndea) to male balb/c mice. the results revealed that ndea-induced hepatic cancer tumor tissue had altered molecular composition compared with normal liver tissue. compared with the normal tissue, the saturation level of membrane phospholipids was observed ... | 2015 | 26349605 |
| utilization of agro-wastes to inhibit aflatoxins synthesis by aspergillus parasiticus: a biotreatment of three cereals for safe long-term storage. | the growth of aspergillus parasiticus and aflatoxins production were inhibited during storage of three important cereals (wheat, maize and rice) using leaves of neem (azadirachta indica) and kikar (acacia nilotica). cereals were inoculated with mould spores and stabilized by neem and kikar leaves-powder. test samples with moisture levels of 21% were stored at 30°c for a period of 9months. aflatoxins were quantified at different time intervals in stored cereals. neem leaves fully inhibited all ty ... | 2015 | 26356116 |
| protective effect of aqueous crude extract of neem (azadirachta indica) leaves on plasmodium berghei-induced renal damage in mice. | malaria is a major public health problem in the world because it can cause of death in patients. malaria-associated renal injury is associated with 45% of mortality in adult patients hospitalized with severe form of the disease. therefore, new plant extracts to protect against renal injury induced by malaria infection are urgently needed. in this study, we investigated the protective effect of aqueous crude extract of azadirachta indica (neem) leaves on renal injury induced by plasmodium berghei ... | 2015 | 26379714 |
| herbal extracts in oral health care - a review of the current scenario and its future needs. | oral diseases are among the major public health problems and the commonest of chronic diseases that affect mankind. the application of natural products for the control of oral diseases is considered as an interesting alternative to synthetic antimicrobials due to their lower negative impact, and for the effort to overcome primary or secondary resistance to the drug during therapy. | 2017 | 26392704 |
| efficacy and insecticidal properties of some essential oils against caryedon serratus (oliver)-a storage pest of groundnut. | during storage groundnut is attacked by number of stored grain pest and management of these insect pests particularly bruchid beetle, caryedon serratus (oliver) is of prime importance as they directly damage the pod and kernels. hence, some essential oils were tested for their insecticidal and fungicidal properties. highest total bruchid mortality was recorded with the application of neem oil and pongamia oil at 10% (v/w) concentration and lowest in eucalyptus oil at 5% (v/w). number of eggs lai ... | 2014 | 26396354 |
| improvement of sperm density in neem-oil induced infertile male albino rats by ipomoea digitata linn. | investigation has been carried out to validate folkloric claim of the potential of ipomoea digitata (id) based on reproductive health status in experimentally induced male albino rats. | 2017 | 26401398 |
| effect of neem (azadirachta indica a. juss) leaf extract on resistant staphylococcus aureus biofilm formation and schistosoma mansoni worms. | there are ethnopharmacological reports supporting the use of neem (azadirachta indica a. juss) leaf against bacterial and worm infections. however there is a lack of studies about its effect on bacterial biofilm formation and schistosoma mansoni worms. this study reports the in vitro effects of neem leaf ethanolic extract (neem ee) on methicillin-resistant staphylococcus aureus (mrsa) biofilm and planktonic aggregation formation, and against s. mansoni worms. | 2015 | 26408045 |
| neem (azadirachta indica) as an alternative therapy for tobacco cessation. | 2015 | 26410984 | |
| in vitro screening of natural feed additives from crustaceans, diatoms, seaweeds and plant extracts to manipulate rumen fermentation. | eight natural products from animal, unicellular algae, brown seaweed and plant origins were chosen according to their theoretical antimicrobial activity: diatomaceous earths (de), insoluble chitosan (ichi), soluble chitosan (chi), seaweed meal (swm), ascophyllum nodosum (asc), laminaria digitata (lam), neem oil (noil) and an ivy fruit extract rich in saponins (ivy). dose-response incubations were conducted to determine their effect on rumen fermentation pattern and gas production, while their an ... | 2016 | 26441121 |
| comparative studies on performance characteristics of ci engine fuelled with neem methyl ester and mahua methyl ester and its respective blends with diesel fuel. | in the present investigation, neem and mahua methyl ester were prepared by transesterification using potassium hydroxide as a catalyst and tested in 4-stroke single cylinder water cooled diesel engine. tests were carried out at constant speed of 1500 rev/min at different brake mean effective pressures. a series of tests were conducted which worked at different brake mean effective pressures, okpa, 1kpa, 2kpa, 3kpa, 4kpa, 5kpa, 6kpa and 6.5kpa. the performance and exhaust emission characteristics ... | 2014 | 26445759 |
| effect of initial temperature treatment on phytochemicals and antioxidant activity of azadirachta indica a. juss. | the present study was undertaken to evaluate the effect of initial temperature treatment on phytochemical and antioxidant potential of commercially important plant azadirachta indica a. juss. the leaves were differentially treated after harvest at temperatures 4, -20, and 110 °c and at room temperature, separately. it was found that a quick drying process at 110 °c followed by air-drying helped in maximum retention of bioactive compounds and antioxidant activity, which was significantly higher t ... | 2016 | 26467740 |
| gedunin and azadiradione: human pancreatic alpha-amylase inhibiting limonoids from neem (azadirachta indica) as anti-diabetic agents. | human pancreatic α-amylase (hpa) inhibitors offer an effective strategy to lower postprandial hyperglycemia via control of starch breakdown. limonoids from azadirachta indica known for their therapeutic potential were screened for pancreatic α-amylase inhibition, a known anti-diabetic target. studies were carried out to reveal their mode of action so as to justify their hypoglycemic potential. of the nine limonoids isolated/semi-synthesized from a.indica and screened for α-amylase inhibition, az ... | 2015 | 26469405 |
| feeding deterrence of cabbage looper (lepidoptera: noctuidae) by 1-allyloxy-4-propoxybenzene, alone and blended with neem extract. | the cabbage looper, trichoplusia ni (hübner) (lepidoptera: noctuidae), is one of the most damaging insect pests of cabbage (brassica oleracea variety capitata) and broccoli (b. oleracea variety italica) in north america. leaf-feeding larvae attack crucifer and vegetable crops in greenhouses and fields. here, we have studied a synthetic feeding deterrent, 1-allyloxy-4-propoxybenzene, and a botanical deterrent, neem (an extract from seeds of azadirachta indica a. de jussieu (meliaceae)), in leaf d ... | 2014 | 26470077 |
| threshold concentration of limonoids (azamax) for preventing infestation by mediterranean fruit fly (diptera: tephritidae). | this study identified the threshold concentration of limonoids for the complete inhibition of oviposition of ceratitis capitata (wiedemann) in grapes 'itália.' choice and no-choice experiments with the insect were performed. the three no-choice bioassays were conducted following a completely randomized design with 18 treatments (three densities of insects [one, two, or three females]×five concentrations of limonoids and control) and 20 replicates. in a free choice bioassay, two fruits per cage ( ... | 2015 | 26470174 |
| efficacy and dose response of soil-applied neem formulations in substrates with different amounts of organic matter, in the control of whiteflies, aleyrodes proletella and trialeurodes vaporariorum (hemiptera: aleyrodidae). | neem products have been used frequently as an alternative to synthetic pesticides, because of their insecticidal, insect antifeedant, and growth-regulating effects. moreover, new formulations are continually being developed and therefore, they have to be evaluated for their efficacy and persistence. in this regard, two soil-applied products-a liquid-based drenching solution neemazal-t and neemazal granules-were evaluated against two whitefly species, aleyrodes proletella l. and trialeurodes vapo ... | 2015 | 26470244 |
| bark extract mediated green synthesis of silver nanoparticles: evaluation of antimicrobial activity and antiproliferative response against osteosarcoma. | in the current investigation we report the biosynthesis potentials of bark extracts of ficus benghalensis and azadirachta indica for production of silver nanoparticle without use of any external reducing or capping agent. the appearance of dark brown color indicated the complete nanoparticle synthesis which was further validated by absorbance peak by uv-vis spectroscopy. the morphology of the synthesized particles was characterized by field emission- scanning electron microscopy (fe-sem) and ato ... | 2016 | 26478285 |
| antibacterial activity of neem nanoemulsion and its toxicity assessment on human lymphocytes in vitro. | neem (azadirachta indica) is recognized as a medicinal plant well known for its antibacterial, antimalarial, antiviral, and antifungal properties. neem nanoemulsion (ne) (o/w) is formulated using neem oil, tween 20, and water by high-energy ultrasonication. the formulated neem ne showed antibacterial activity against the bacterial pathogen vibrio vulnificus by disrupting the integrity of the bacterial cell membrane. despite the use of neem ne in various biomedical applications, the toxicity stud ... | 2015 | 26491309 |
| the bioefficacy of crude extracts of azadirachta indica (meliaceae) on the survival and development of myiasis-causing larvae of chrysomya bezziana (diptera: calliphoridae). | myiasis is a type of parasitosis originating from the invasion of tissues of live humans and other vertebrates by dipteran larvae. the old world screwworm fly—chrysomya bezziana—is known worldwide in the tropical regions for causing myiasis among man and domestic animals, thereby leading to health hazards and severe economic losses to the dairy farmers. management techniques for controlling populations of the fly are needed to minimize these losses. plant-derived materials have been increasingly ... | 2016 | 26494546 |