Publications
| Title | Abstract | Year Filter | PMID(sorted ascending) Filter |
|---|
| omalizumab attenuates airway inflammation and interleukin-5 production by mononuclear cells in patients with severe allergic asthma. | omalizumab, an anti-immunoglobulin e monoclonal antibody, has shown an inhibitory effect on airway inflammation, which may be associated with clinical improvement of severe asthma. this study evaluated changes in airway inflammation and cytokine release by the peripheral blood mononuclear cells (pbmcs) of japanese patients with severe asthma after administration of omalizumab. | 2013 | 23711861 |
| oxidative stress status in umbilical cord blood from neonates born to mothers with atopic asthma. | our objective was to assess the oxidative stress status and analyse the relationship between an oxidant/antioxidant imbalance and the mediator release properties of cord blood basophils from neonates born to mothers with atopic asthma. | 2014 | 23735076 |
| [the benefits of using basophil activation test as a diagnostic tool prior to specific immunotherapy with inhalant allergens]. | routine qualification for specific immunotherapy (sit) is based on clinical history and skin prick tests (spt) or specific ige (sige). in cases of discordance between these two, basophil activation test (bat) may be decisive. the aim of the present study was to determine the specificity and sensitivity of bat, sige, and spt, and to analyse cases, in which clinical data and spt alone would result in wrongful qualification for sit. | 2012 | 23750433 |
| the relation of multiple sclerosis with allergy and atopy: a case control study. | multiple sclerosis (ms) and allergy are believed to up regulate t helper cell type 1 (th1) and t helper cell type 2 (th2) responses, respectively. it has been shown that disequilibrium in the ratio of th1/th2 activities may increase frequency of one disease and decrease the frequency of the other. the aim of this study was to investigate the relation of ms with allergy and atopy in new diagnosed ms patients. this case-control study was conducted on 40 new diagnosed ms patients and the same numb ... | 2013 | 23754358 |
| acaricidal toxicities of 1-hydroxynaphthalene from scutellaria barbata and its derivatives against house dust and storage mites. | the essential oil of scutellaria barbata was extracted using a steam distillation and then evaluated via fumigant and contact toxicity bioassays against dermatophagoides farinae, dermatophagoides pteronyssinus, and tyrophagus putrescentiae. the acaricidal toxicities of 1-hydroxynaphthalene from s. barbata oil and its derivatives were determined and compared with those of benzyl benzoate. based on the ld50 values of 1-hydroxynaphthalene derivatives against d. farinae, d. pteronyssinus, and t. put ... | 2013 | 23757178 |
| rutin suppresses atopic dermatitis and allergic contact dermatitis. | atopic dermatitis (ad) and allergic contact dermatitis (acd) is a common allergic inflammatory skin disease caused by a combination of eczematous, scratching, pruritus and cutaneous sensitization with allergens. the aim of our study was to examine whether rutin, a predominant flavonoid having anti-inflammatory and antioxidative potential, modulates ad and acd symptoms. we established an atopic dermatitis model in balb/c mice by repeated local exposure of house dust mite (dermatophagoides farinae ... | 2013 | 23760007 |
| polydesensitisation with reducing elevated serum total ige by ifn-gamma therapy in atopic dermatitis: ifn-gamma and polydesensitisation (pds). | ad patients exhibit sensitisation to multiple allergens due to a th1/th2 imbalance. until now, it was impossible to improve the polysensitised status and elevated serum total ige levels. in this study, the effects of ifn-gamma on systemic polysensitisation to multiple allergens and on serum total ige levels are investigated. | 2013 | 23786862 |
| 850nm light-emitting-diode phototherapy plus low-dose tacrolimus (fk-506) as combination therapy in the treatment of dermatophagoides farinae-induced atopic dermatitis-like skin lesions in nc/nga mice. | light emitting diode (led) phototherapy is an effective alternative for the treatment of inflammatory skin disorders. tacrolimus (fk-506) is a potent immunomodulating agent, which has been used to treat ad. combination therapy is often used in the treatment of ad to improve therapeutic efficacy or to reduce the dose of each drug. | 2013 | 23810774 |
| [comparison of serum specific ige and skin prick test in allergic rhinitis patients sensitive to dust mite]. | to investigate the correlation of serum specific ige and skin prick test in allergic rhinitis patients sensitive to dust mite and the difference between the results. | 2013 | 23858721 |
| acaricidal activities of β-caryophyllene oxide and structural analogues derived from psidium cattleianum oil against house dust mites. | this study was to evaluate the acaricidal activities of an active compound isolated from psidium cattleianum and structural analogues against dermatophagoides farinae and d. pteronyssinus. β-caryophyllene oxide was isolated using chromatographic techniques. | 2014 | 23861316 |
| the spectrum of aeroallergen sensitization in children diagnosed with asthma during first 2 years of life. | aeroallergens may trigger symptoms in sensitized children with asthma. documentation of sensitization is crucial to enable effective implementation of measures to prevent asthma exacerbations. to document the sensitization patterns of very young children (≤2 years) with asthma, we retrospectively analyzed the skin-prick test (spt) results of the largest referral center in the country. during a 4-year period, 432 children (median age, 1.21 years; male/female, 2.35) were referred. all patients had ... | 2016 | 23883600 |
| sublingual immunotherapy in children with allergic rhinoconjunctivitis mono-sensitized to house-dust-mites: a double-blind-placebo-controlled randomised trial. | although sublingual immunotherapy (slit) has been demonstrated to be a safe and efficient treatment in children with seasonal allergic rhinitis (ar), there is little evidence on the efficacy of slit with house-dust-mite (hdm) extract in children with isolated perennial ar. | 2013 | 23886432 |
| a case of mite-ingestion-associated exercise- induced anaphylaxis mimicking wheat-dependent exercise-induced anaphylaxis. | we present a case of mite-ingestion-associated exercise-induced anaphylaxis mimicking wheat-dependent exercise-induced anaphylaxis (wdeia). a 17-year-old boy was referred for an episode of anaphylaxis while jogging, 1.5 h after having eaten okonomiyaki (a japanese pancake). laboratory measures revealed a slightly elevated specific immunoglobulin e (ige) antibody against omega-5 gliadin (0.41 kua/l) and a marked elevation of specific ige antibody against house-dust mite, dermatophagoides farinae ... | 2013 | 23921625 |
| pcr detection of the 14.5 antibacterial nlpc/p60-like dermatophagoides pteronyssinus protein in dermatophagoides farinae (acari: pyroglyphidae). | house dust mites produce antibacterial proteins suppressing bacterial growth. the 14.5-kda bacteriolytic protein (uniprotkb q8mwr6) has been known in dermatophagoides pteronyssinus trouessart. we have applied polymerase chain reaction and reverse transcription-pcr to detect a homologous gene sequence coding for a q8mwr6-related protein in dermatophagoides farinae (hughes) using genomic dna and total rna, respectively. the resulting pcr product of expected size, 243 bp, was obtained from both der ... | 2013 | 23926795 |
| the effect of montelukast on wheal reactions in skin prick tests: a double-blind-placebo-controlled randomized trial. | it is well-known that number of drugs may interfere with wheal reactions in skin prick test. however, the effect of long-term use of montelukast, a cystenil leukotriene receptor antagonist, on skin prick test hasn't been full elucidated. the aim of present study was to demonstrate the effect of montelukast on skin prick tests (spt). | 2013 | 23958393 |
| a genome-wide association study of total serum and mite-specific iges in asthma patients. | immunoglobulin e (ige) is one of the central players in asthma and allergic diseases. although the serum ige level, a useful endophenotype, is generally increased in patients with asthma, genetic factors influencing ige regulation in asthma are still not fully understood. to identify the genetic variations associated with total serum and mite-specific iges in asthmatics, a genome-wide association study (gwas) of 657,366 single nucleotide polymorphisms (snps) was performed in 877 korean asthmatic ... | 2013 | 23967269 |
| clinical efficacy and compliance of sublingual immunotherapy with dermatophagoides farinae drops in patients with atopic dermatitis. | the oral route for administration of allergen immunotherapy has been explored since the 1900s. we attempted to evaluate the efficacy and safety of sublingual immunotherapy (slit) with dermatophagoides farinae drops in patients with atopic dermatitis (ad) and investigate related factors influencing the patients' compliance. | 2014 | 23968339 |
| the impact of pulmonary tuberculosis treatment on the prevalence of allergic rhinitis. | atopy is a syndrome characterized by immediate hypersensitivity reactions to common environmental antigens. the "hygiene hypothesis" stipulates that childhood infections are associated with a lower risk of allergies. not much has been published about the effects that the treatment of pulmonary tuberculosis (tb) has on allergies, specifically allergic rhinitis. we conducted a study to investigate the prevalence of allergic rhinitis in patients with pulmonary tb before and after treatment of their ... | 2013 | 23975489 |
| association between pet ownership and the sensitization to pet allergens in adults with various allergic diseases. | as pet ownership increases, sensitization to animal allergens due to domestic exposure is a concern. sensitization to animal allergens may occur from indirect exposure, as well as direct ownership of animals. however, there have been conflicting results regarding the association between pet ownership and sensitization to animal allergens in adults. | 2013 | 24003386 |
| [relative potency of allergenic extracts from mites in patients with asthma and allergic rhinitis]. | skin tests for specific diagnosis of allergies require high quality extracts, which can be measured by the determination of allergenic potency, utilizing different concentrations of extracts from a manufacturer. | 2013 | 24007830 |
| [correlation of cutaneous reactivity between allergenic extracts of dermatophagoides pteronyssinus and dermatophagoides farinae with blomis tropicalis in patients with allergic rinitis and asthma]. | there are documented molecular homologies between mites from the same group, but intergroup characteristics are not. although mites share the same taxonomic order, there are species antigenically distinct. at the present we dont know clearly the differences in cutaneous reactivity among several house dust mites species. | 2013 | 24007986 |
| [sensitization to house dust and storage mites in allergic adults from the south of mexico city]. | mites are the most common cause of respiratory allergy. sensitization to house dust mites is estimated at 30%. families euroglyphus and dermatophagoides, are the most important. recently, storage mites, from the families acaridae and glyciphagidae, have become more important as a cause of allergic respiratory diseases. | 2015 | 24008067 |
| different anti-apoptotic effects of normal and asthmatic serum on normal eosinophil apoptosis depending on house dust mite-specific ige. | we investigated the effect of asthmatic serum on constitutive eosinophil apoptosis in normal subjects. eosinophil apoptosis in normal subjects was inhibited by asthmatic serum but not normal serum. in a detailed analysis based on the presence of house dust mite (hdm) ige, hdm ige-positive (+) asthmatic serum was more effective for eosinophil apoptosis than that of hdm ige-negative (-) asthmatic serum. hdm ige+ asthmatic serum inhibited both hdm ige- and hdm ige+ normal eosinophil apoptosis, and ... | 2013 | 24065529 |
| [analysis of allergen variation for 3292 patients with allergic rhinitis]. | to investigate the variation of common allergens in patients with allergic rhinitis in recent 4 years in tianjin first center hospital. | 2013 | 24103176 |
| acaricidal activities of bicyclic monoterpene ketones from artemisia iwayomogi against dermatophagoides spp. | the acaricidal properties of 1,7,7-trimethylbicyclo[2.2.1]heptan-2-one isolated from artemisia iwayomogi and its structural analogues were evaluated against dermatophagoides farinae and d. pteronyssinus, and their effects were compared with that of the commercial acaricide benzyl benzoate. based on the 50 % lethal dose (ld50) values against d. farinae, 1,7,7-trimethylbicyclo[2.2.1]heptan-2-one (0.82 μg/cm(2)) was 9.71 times more effective than benzyl benzoate (7.96 μg/cm(2)), followed by (1r)-1, ... | 2014 | 24114336 |
| epidemiology of ige-dependent allergic diseases in elderly patients in poland. | there is a growing allergy problem in elderly patients. the epidemiology of atopic bronchial asthma (ba), allergic rhinitis, and atopic dermatitis (ad) was analyzed in an elderly polish population. | 2013 | 24119595 |
| [analysis of clinical features and allergic status of asthmatic patients with positive serum mycosis-specific ige]. | to improve understanding of the clinical characteristics and diagnosis of allergic bronchopulmonary mycosis (abpm). | 2013 | 24252730 |
| 20-o-β-d-glucopyranosyl-20(s)-protopanaxadiol-fortified ginseng extract attenuates the development of atopic dermatitis-like symptoms in nc/nga mice. | ginseng and ginsenosides are frequently used in the treatment of chronic inflammatory diseases. recently, 20-o-β-d-glucopyranosyl-20(s)-protopanaxadiol (gpd), the main metabolite of ginsenosides, was reported to have both anti-allergic and anti-pruritic effects. the immunomodulatory effects of gpd-fortified ginseng extract (gfge) on atopic dermatitis (ad)-like symptoms in mice were investigated. this study was designed to investigate the preventive effect of gfge on ad-like symptoms. | 2014 | 24269244 |
| [identification of house dust mite fauna from allergic patients' mattress in six mexican states]. | house dust is considered an important source of aeroallergens, and the mites living there, are the main cause of allergy to it. in méxico, there have been few about house dust fauna, and mostly limited to méxico city. | 2015 | 24274602 |
| ige reactivity to acarus siro extract in korean dust mite allergic patients. | although specific ige to the storage mite acarus siro is often detected, there are no detailed studies on ige reactivity to a. siro in korea. this study was undertaken to investigate the cross-reactivity to the mite species dermatophagoides pteronyssinus, dermatophagoides farinae, tyrophagus putrescentiae, and a. siro in korean mite allergic patients. specific ige values were determined for the four mite species and a competitive inhibition test was performed for mite extracts using the immunoca ... | 2014 | 24287899 |
| verbenone structural analogues isolated from artemesia aucheri as natural acaricides against dermatophagoides spp. and tyrophagus putrescentiae. | the acaricidal activities of artemisia aucheri oil and (1s)-(-)-verbenone structural analogues were evaluated using a fumigant method against dermatophagoides farinae , dermatophagoides pteronyssinus , and tyrophagus putrescentiae and then compared to those of benzyl benzoate. on the basis of the ld50 values against d. farinae , (1s)-(-)-verbenone (1.38 μg/cm(2)) was about 7.4 times more active than benzyl benzoate (10.15 μg/cm(2)), followed by (+)-trans-myrtanol (2.27 μg/cm(2)), (-)-trans-myrta ... | 2013 | 24295367 |
| time-dependent progression from the acute to chronic phases in atopic dermatitis induced by epicutaneous allergen stimulation in nc/nga mice. | atopic dermatitis (ad) is a complicated skin condition influenced by genetic background and environmental factors. in this study, we applied dermatophagoides farinae body extract (dfe) to the barrier-disrupted skin of nc/nga mice twice a week for 8 weeks to identify the clinical and immunological factors in ad progression. repeated application of the dfe to the skin of nc/nga mice showed the similar consequences for the natural course of progression in human ad, histologically and immunologicall ... | 2014 | 24299269 |
| prevalence of allergen sensitization, most important allergens and factors associated with atopy in children. | knowledge of the profile of allergen sensitization among children is important for planning preventive measures. the objective of this study was to assess the prevalence and profile of sensitization to inhaled allergens and food among children and adolescents in an outpatient population in the city of palmas. | 2013 | 24310798 |
| [efficacy of sublingual immunotherapy with dermatophagoides farinae drops in monosensitized and polysensitized patients with allergic rhinitis]. | to compare the efficacy of sublingual immunotherapy (slit) with standardized dermatophagoides farinae drops in monosensitized and polysensitized patients with allergic rhinitis. | 2013 | 24313202 |
| 7,3',4'-trihydroxyisoflavone ameliorates the development of dermatophagoides farinae-induced atopic dermatitis in nc/nga mice. | atopic dermatitis is an inflammatory and chronically relapsing skin disorder that commonly occurs in children; the number of atopic dermatitis patients is increasing. the cause and mechanism of atopic dermatitis have not been defined clearly, although many studies are ongoing. epidemiological studies suggest that soybean and its isoflavones have immunoregulatory activities. here, we report that 7,3',4'-trihydroxyisoflavone (7,3',4'-thif), a major metabolite of daidzin, effectively inhibited lipo ... | 2013 | 24324516 |
| alpha-actinin is a new type of house dust mite allergen. | main indoor allergens for humans are from house dust mites. there are more than 30 allergens in dermatophagoides farinae but only fourteen allergens have been identified from this mite including der f 1-3, 6, 7, 10, 11, 13-18, and 22. a native allergen protein (der f 24, 90 kda) was purified from d. farinae by gel filtration and anionic exchange liquid chromatography combined with ige immunodetection. its primary structure was determined by edman degradation, mass spectrometry analysis and cdna ... | 2013 | 24324688 |
| the effect of rhinovirus on airway inflammation in a murine asthma model. | the aim of the present study was to investigate the differences in lower airway inflammatory immune responses, including cellular responses and responses in terms of inflammatory mediators in bronchoalveolar lavage fluid (balf) and the airway, to rhinovirus (rv) infection on asthma exacerbation by comparing a control and a murine asthma model, with or without rv infection. | 2013 | 24348661 |
| the drinking effect of hydrogen water on atopic dermatitis induced by dermatophagoides farinae allergen in nc/nga mice. | hydrogen water (hw) produced by electrolysis of water has characteristics of extremely low oxidation-reduction potential (orp) value and high dissolved hydrogen (dh). it has been proved to have various beneficial effects including antioxidant and anti-inflammatory effects; however, hw effect on atopic dermatitis (ad), an inflammatory skin disorder, is poorly documented. in the present study, we examined the immunological effect of drinking hw on dermatophagoides farinae-induced ad-like skin in n ... | 2013 | 24348704 |
| [analysis of mite-allergic characteristics in patients with allergic rhinitis]. | to investigate the characteristics of allergic rhinitis sensitized with mite, providing the evidence for the treatment plan of allergic rhinitis in tianjin area. | 2013 | 24358792 |
| therapeutic effects and immunomodulation of suanbo mineral water therapy in a murine model of atopic dermatitis. | balneotherapy is widely used as an alternative treatment modality for ad. although the clinical benefit of some mineral waters has been established, their mechanisms of action in alleviating ad are only partly understood. | 2013 | 24371394 |
| influence of the adjuvants and genetic background on the asthma model using recombinant der f 2 in mice. | der f 2 is the group 2 major allergen of a house dust mite (dermatophagoides farinae) and its function has been recently suggested. to determine the optimal condition of sensitization to recombinant der f 2 (rder f 2) in murine model of asthma, we compared the effectiveness with different adjuvants in balb/c and c57bl/6 mice. mice from both strains sensitized with rder f 2 by intraperitoneal injection or subcutaneous injection on days 1 and 14. the dosage was 20 µg. freund's adjuvants with pertu ... | 2013 | 24385949 |
| toll-like receptors required for dermatophagoides farinae to activate nf-κb. | body and excrement extracts from dermatophagoides farinae were used to study stimulation of toll-like receptors (tlrs). the excrement extract stimulated nuclear factor (nf)-κb-dependent reporter activity to an extent similar to lipopolysaccharide (lps) in a mouse macrophage cell line, j774a.1, but the activity of the body extract was negligible. the excrement extract also activated nf-κb in hek293 cells expressing tlr1/tlr2, tlr2/tlr6 and cd14/tlr4/md-2, whereas no activation was observed in cel ... | 2014 | 24389483 |
| sensitisation to mites in a group of patients with asthma in yaounde, cameroon: a cross-sectional study. | sensitisation of asthmatic patients to mites in sub-saharan africa has been less described. the aim of this study was to assess the prevalence and determinants of sensitisation to mites in asthmatic adolescents and adults in yaounde, cameroon. | 2014 | 24390384 |
| variability of offending allergens of allergic rhinitis according to age: optimization of skin prick test allergens. | this study evaluates offending allergens in patients with allergic rhinitis (ar) according to age that establish a minimal panel for skin prick test (spt) allergens required to identify if a patient is sensitized. | 2014 | 24404393 |
| intestinal parasitic infections and atopic dermatitis among venezuelan warao amerindian pre- school children. | we evaluated the influence of intestinal parasitic infection on food sensitization associated to the severity of atopic dermatitis (ad) in a group of warao amerindian pre- school children. | 2014 | 24417507 |
| [development of allergic rhinitis and its impact on asthma: 4-5 year follow-up study of preschool children]. | to observe the development of allergic rhinitis (ar) in preschool children, and the variation of sensitization to airborne allergens 5 years later, also the link between ar and asthma. | 2013 | 24444631 |
| dectin-2 regulates the effector phase of house dust mite-elicited pulmonary inflammation independently from its role in sensitization. | the myeloid c-type lectin receptor dectin-2 directs the generation of th2 and th17 immune responses to the house dust mite dermatophagoides farinae through the generation of cysteinyl leukotrienes and proinflammatory cytokines, respectively, but a role for dectin-2 in effector phase responses has not been described. in this study, we demonstrate that administration of the dectin-2 mab solely at the time of d. farinae challenge abrogated eosinophilic and neutrophilic inflammation in the bronchoal ... | 2014 | 24453247 |
| skin prick test reactivity to common aero and food allergens among children with allergy. | the prevalence of allergic diseases has risen in the last decades. the objective of this study was to determine the common allergens in children via the skin prick test. | 2014 | 24453391 |
| [efficacy of sublingual immunotherapy with dermatophagoides farinae drops in preschool and school-age children with allergic asthma and allergic rhinitis]. | to evaluate the efficacy of specific sublingual immunotherapy (slit) with dermatophagoides farinae drops on children with allergic asthma and allergic rhinitis of the preschool and school-age groups of children and adolescents. | 2013 | 24484557 |
| acaricidal activities against house dust mites of spearmint oil and its constituents. | the aim of this study was to evaluate the acaricidal activities of spearmint oil and carvone derivatives against house dust mites using contact and fumigant toxicity bioassays to replace benzyl benzoate as a synthetic acaricide. based on the ld50 values, the contact toxicity bioassay revealed that dihydrocarvone (0.95 and 0.88 µg/cm2) was 7.7 and 6.8 times more toxic than benzyl benzoate (7.33 and 6.01 µg/cm2) against dermatophagoides farinae and dermatophagoides pteronyssinus, respectively, fol ... | 2014 | 24488719 |
| block copolymer/dna vaccination induces a strong allergen-specific local response in a mouse model of house dust mite asthma. | allergic asthma is caused by abnormal immunoreactivity against allergens such as house dust mites among which dermatophagoides farinae (der f) is a common species. currently, immunotherapy is based on allergen administration, which has variable effect from patient to patient and may cause serious side effects, principally the sustained risk of anaphylaxis. dna vaccination is a promising approach by triggering a specific immune response with reduced allergenicity. | 2014 | 24497934 |
| the role of molds in the relation between indoor environment and atopy in asthma patients. | the effect of mold fungi to allergic sensitization is not well-known. we aimed to evaluate the role of molds in the relation between indoor environment and atopy in asthmatics. | 2013 | 24523798 |
| high-intensity swimming exercise increases dust mite extract and 1-chloro-2,4-dinitrobenzene-derived atopic dermatitis in balb/c mice. | the aim of this study was to investigate the effect of high-intensity swimming exercise (hise) on atopic dermatitis (ad). for the study, we established an ad model in balb/c mice by repeated local exposure of house dust mite extract (dermatophagoides farinae extract, dfe) and 1-chloro-2,4-dinitrobenzene (cdnb) to the ears. after hise for 4 weeks, epidermal thickness, mast cell infiltration, serum immunoglobulin e (ige), and histamine were measured. in addition, the gene expression of interleukin ... | 2014 | 24526290 |
| cysteinyl leukotriene receptor antagonist regulates allergic airway inflammation in an organ- and cytokine-specific manner. | cysteinyl leukotrienes (cys-lts) are very important factors in the pathophysiology of bronchial asthma. cys-lt receptor antagonists (ltras) decrease allergic airway inflammation. the aim of the present study was to determine the differential effects of ltras and corticosteroids on allergic airway inflammation and allergen-specific cytokine production from lymphoid tissues using a murine model of asthma. | 2014 | 24561545 |
| the relationship between a specific ige level and asthma outcomes: results from the 2005-2006 national health and nutrition examination survey. | allergen exposure is associated with increased specific ige (sige), and allergen exposure plus sensitization is predictive of asthma outcomes. however, it is not known if sige is predictive of asthma outcomes in the absence of exposure data. | 2014 | 24565622 |
| effects of sublingual immunotherapy for dermatophagoides farinae on th17 cells and cd4(+) cd25(+) regulatory t cells in peripheral blood of children with allergic asthma. | sublingual immunotherapy is becoming a more common treatment for allergic diseases, particularly in pediatric clinics. this type of treatment is highly effective for dermatophagoides farinae allergy, but the mechanisms resulting in immune tolerance have not been investigated. we explored the effects of sublingual immunotherapy with d. farinae drops on populations of subsets of t immune cells, specifically th17 cells and cd4(+) cd25(+) regulatory t cells (treg cells), in peripheral blood of child ... | 2014 | 24591191 |
| evaluation of the acaricidal toxicities of camphor and its structural analogues against house dust mites by the impregnated fabric disc method. | the acaricidal activities of (±)-camphor structural analogues against house dust mites were evaluated using the impregnated fabric disc bioassay. | 2014 | 24616046 |
| mite species identification in the production of allergenic extracts for clinical use and in environmental samples by ribosomal dna amplification. | the identification of allergy-causing mites is conventionally based on morphological characters. however, molecular taxonomy using ribosomal dna (rdna) may be particularly useful in the analysis of mite cultures and purified mite fractions in the production of allergenic extracts. full-length internal transcribed spacers (its1 and its2) were obtained from dermatophagoides farinae, dermatophagoides pteronyssinus, dermatophagoides microceras and euroglyphus maynei (astigmata: pyroglyphidae), glycy ... | 2014 | 24617319 |
| [the analysis of the allergens in 576 patients with allergic rhinitis in qingyang of gansu province]. | to investigate the allergens distribution of 576 allergic rhinitis patients in qingyang, and to provide basic epidemiologic information for the prevention and treatment of allergic rhinitis. | 2013 | 24620661 |
| artemisia capillaris inhibits atopic dermatitis-like skin lesions in dermatophagoides farinae-sensitized nc/nga mice. | artemisia capillaries thunb. (ac) has been used to treat inflammatory and hepatic disorders such as hepatic injury, hepatic fibrosis and hepatitis. however, the efficacy of ac against atopic dermatitis (ad), an inflammatory disease, has not been examined. in the present study, ac was evaluated for anti-inflammatory and anti-ad effects using both in vitro and in vivo systems. | 2014 | 24624888 |
| the association between serum vitamin d level and immunoglobulin e in korean adolescents. | vitamin d has immune modulatory functions, and thus its relationship with allergic disease has been evaluated in a number of studies. however, no concrete link between serum ige level and vitamin d has been established. thus, the purpose of study was to confirm the association of serum vitamin d level with the serum ige (total and dematophagoides farinae specific ige) in korean adolescents. | 2014 | 24630983 |
| atopic phenotypes identified with latent class analyses at age 2 years. | atopic sensitization (ie, atopy) is the most commonly reported risk factor for asthma. recent studies have begun to suggest that atopy, as conventionally defined, might be an umbrella term that obfuscates more specific allergic disease types. | 2014 | 24636082 |
| house dust mites: a risk factor to be considered for occupational safety or source of work-related allergens. | house dust mites (hdm) can be found worldwide where human beings live independent from the climate and are a major source of multiple allergens. mite allergens sensitize and induce perennial rhinitis, asthma, or atopic dermatitis in a large portion of patients with allergic disease particularly children. there is convincing evidence that avoidance of mite allergen can effectively reduce allergic symptoms. this study examined dust from a military hospital and the private home of some nursing staf ... | 2013 | 24640866 |
| component-resolved diagnosis (crd): is it worth it? frequency and differentiation in rhinitis patients with mite reactivity. | component-resolved diagnosis (crd) using microarray technology has recently been introduced with the aim to improve diagnosis of allergy. the aim of this study was to compare performance of this allergen microarray to those of an established extract-based skin prick testing (spt).45 patients with allergic rhinitis were studied (16 children and 29 adults). spt to dermatophagoides pteronyssinus, dermatophagoides farinae and blomia tropicalis extracts and allergen microarray immunocap isac were car ... | 2014 | 24659159 |
| inhibitory effect of galangin on atopic dermatitis-like skin lesions. | galangin is a member of the flavonol class of flavonoids having anti-inflammatory and anti-oxidative potential. previously we reported the inhibitory effect of galangin on the mast cell-mediated allergic inflammation. for incremental research, we investigated the effects of galangin on atopic dermatitis (ad)-like skin lesions and underlying mechanisms of action. we established an atopic dermatitis model in balb/c mice by repeated local exposure of house dust mite (dermatophagoides farinae) extra ... | 2014 | 24675422 |
| antiatopic dermatitis effect of artemisia iwayomogi in dust mice extract-sensitized nc/nga mice. | aims. artemisia iwayomogi (ai) has been used for fever reduction, diuresis, and hepatoprotection in korea. the present study was performed to evaluate the anti-inflammatory and antiatopic dermatitis effects of ai using both in vitro and in vivo systems. methods. the compositions in ai were analyzed by hplc. to determine the anti-inflammatory effects of ai, the production of nitric oxide (no) was measured in lipopolysaccharide treated raw264.7 cells. histamine levels were assayed to evaluate the ... | 2014 | 24707309 |
| bartonella-like bacteria carried by domestic mite species. | bacteria of the genus bartonella are carried by haematophagous mites, ticks, fleas and flies, and attack the erythrocytes of mammals. here we describe a bartonella-like clade, a distinct group related to bartonellaceae, in stored-product mites (acari: astigmata) and a predatory mite cheyletus eruditus (acari: prostigmata) based on the analysis of cloned 16s rrna gene sequences. by using the clade-specific primers, closely related bartonella-like 16s rrna sequences were amplified from both labora ... | 2014 | 24711066 |
| the effects of alcohol consumption and smoking on allergy risk in korean adults. | the immune-modulating effects of alcohol and smoking are well known through a great body of research. furthermore, many studies have been performed on the influence of alcohol and smoking on the development of allergic disease. however, previous studies have reported conflicting results with associations between alcohol intake or smoking and risk of allergy. the purpose of this study was to evaluate the effects of alcohol consumption and smoking on total serum immunoglobulin e (tige) and prevale ... | 2014 | 24717878 |
| efficacy and safety of sublingual immunotherapy in children aged 3-13 years with allergic rhinitis. | sublingual immunotherapy (slit) is recommended for allergic diseases. however, clinical studies containing evidence-based data of this treatment in young children, which is rarely reported in the literature, are needed. this study was designed to assess the efficacy and safety of slit in children, including very young children. | 2014 | 24717951 |
| effects of topical application of a recombinant staphylococcal enterotoxin a on dncb and dust mite extract-induced atopic dermatitis-like lesions in a murine model. | atopic dermatitis (ad) is a chronic inflammatory skin disease with biphasic t cell-mediated abnormalities. staphylococcal superantigens contribute to the exacerbation of inflammation in ad. the underlying immunopathological mechanisms are not fully understood. | 2016 | 24721827 |
| direct analysis of airborne mite allergen (der f1) in the residential atmosphere by chemifluorescent immunoassay using bioaerosol sampler. | dermatophagoides farinae allergen (der f1) is one of the most important indoor allergens associated with allergic diseases in humans. mite allergen der f1 is usually associated with particles of high molecular weight; thus, der f1 is generally present in settled dust. however, a small quantity of der f1 can be aerosolized and become an airborne component. until now, a reliable method of detecting airborne der f1 has not been developed. the aim of this study was to develop a fiber-optic chemifluo ... | 2014 | 24725888 |
| human placental extract reduces allergic inflammation in a murine allergic rhinitis model. | in this study, we addressed the immunotherapeutic potential of human placental extract (hpe) in a murine allergic rhinitis (ar) model and explored its immunological mechanisms. | 2014 | 24729028 |
| association study on adam33 polymorphisms in mite-sensitized persistent allergic rhinitis in a chinese population. | the adam33 gene has been identified as a potentially important asthma candidate gene and polymorphisms in this gene have been shown to be associated with asthma and seasonal allergic rhinitis. | 2014 | 24751681 |
| therapeutic effects of full spectrum light on the development of atopic dermatitis-like lesions in nc/nga mice. | full spectrum light (fsl) includes uva, visible light and infrared light. many studies have investigated the application of fsl in severe cases of atopic dermatitis (ad) in humans; however, fsl has not yet been studied in an animal model. the purpose of this study was to evaluate the therapeutic effects of fsl on ad-like skin lesions using nc/nga mice, with the aim of mitigating itching and attenuating the expression of adhesion molecules. we examined the effects of fsl on mite allergen-treated ... | 2014 | 24773136 |
| the complete mitochondrial genome of the brown leg mite, aleuroglyphus ovatus (acari: sarcoptiformes): evaluation of largest non-coding region and unique trnas. | the circular mitochondrial genome (mitogenome) of aleuroglyphus ovatus was sequenced. it was 14,328 bp long, and consisted of 37 coding genes including 13 protein-coding genes, two ribosomal rna genes, and 22 transfer rna genes. this is the first description of the complete mitogenome of a species in the acaridae (acari: sarcoptiformes). the mtdna gene order for a. ovatus is identical to those of dermatophagoides farinae and d. pteronyssinus, but distinctly different from the mtdna of other acar ... | 2014 | 24777358 |
| co-sensitization to silkworm moth (bombyx mori) and 9 inhalant allergens among allergic patients in guangzhou, southern china. | this study aimed to investigate the profile of sensitization to silkworm moth (bombyx mori) and other 9 common inhalant allergens among patients with allergic diseases in southern china. | 2014 | 24787549 |
| equine intradermal test threshold concentrations for house dust mite and storage mite allergens and identification of stable acari fauna. | house dust mite (hdm) and storage mite (sm) stable fauna and their associated equine intradermal test (idt) threshold concentrations (tcs) for the midwestern region of the usa are unknown. | 2014 | 24800265 |
| [cloning, expression and identification of der f7 gene from dermatophagoides farinae and its immunological characteristics]. | to clone and express der f7 gene of dermatophagoides farinae, and identify its immunogenicity. | 2013 | 24818391 |
| [cloning, expression and analysis of der f mag 29 allergen of dermatophagoides farinae]. | the full-length mag 29 gene of dermatophagoides farinae was amplified by rt-pcr with a pair of specific primers. the pcr product was cloned into pcold tf dna vector. the constructed plasmid pcold tf-mag 29 was transformed into e. coli bl21 and followed by expression of the protein induced by iptg. the recombinant protein was analyzed by sds-page. the full-length mag 29 gene was 429 bp. a specific band (mr 63,000) were detected in the whole cells, the supernatant, and the precipitate. bioinformat ... | 2013 | 24818419 |
| [ultrastructure of the digestive system in dermatophagoides farinae (acariformes:pyroglyphidae)]. | fifty living mites (dermatophagoides farinae) were fixed in 2.5% glutaraldehyde, postfixed in 1% osmium tetroxide, dehydrated in a graded ethanol series, embedded in embedding medium. the ultrastructure of the digestive tract in d. farinae was observed by serial ultrathin sections with a transmission electron microscope. the alimentary canal of d. farinae consists of the cuticle-lined foregut and hindgut separated by a microvilli-lined midgut (anterior midgut, posterior midgut). there are differ ... | 2013 | 24818423 |
| [analysis of allergen skin test results in 1124 patients with allergic rhinitis in the junction of guangdong and guangxi provinces]]. | to investigate the characteristics and influence factors of sensitization hy allergens in patients with allergic rhinitis in the junction of guangdong and guangxi provinces. | 2014 | 24826453 |
| expression, cloning, and ige-binding of the full-length dust mite allergen der f 8. | dermatophagoides farinae, a domestic mite species, produces some of the most potent allergens that contribute to allergy in china and worldwide. we sought to clone and express the group 8 allergen of d. farinae (der f 8) to investigate its ige-binding reactivity. the full-length cdna encoding der f 8 was generated by using rt-pcr and 5' race, cloned into pcold-tf expression vector, confirmed by nucleotide sequencing, sub-cloned into pet-28b (+), and transfected into e. coli bl21 cells for expres ... | 2014 | 24838264 |
| a nationwide survey of inhalant allergens sensitization and levels of indoor major allergens in korea. | the higher prevalence of respiratory allergic disease may be due to increased exposure to inhalation allergens. we conducted a survey of allergic diseases in autumn and winter with detection of major indoor allergens in major cities in korea. | 2014 | 24843797 |
| mite and booklouse fauna from vacuumed dust samples from beijing. | a significant-source of allergens come from house dust that contain particles derived from arthropods, molds, and pet dander. this study evaluated mite and booklouse fauna from vacuumed dust samples in beijing china (a temperate zone). our survey was carried out in beijing in the homes of mite allergic patients who visited our allergy department. in total, 38 homes were selected for the collection of dust samples by vacuuming, from december 2008 to january 2010. the flotation method was used to ... | 2014 | 24843802 |
| use of activity monitors for assessment of pruritus in an acute model of canine atopic dermatitis. | we developed a canine model of acute atopic dermatitis to evaluate the potential of compounds to treat pruritus and skin lesions induced in dermatophagoides farinae (df)-sensitized dogs. | 2014 | 24889924 |
| in silico prediction of t and b cell epitopes of der f 25 in dermatophagoides farinae. | the house dust mites are major sources of indoor allergens for humans, which induce asthma, rhinitis, dermatitis, and other allergic diseases. der f 25 is a triosephosphate isomerase, representing the major allergen identified in dermatophagoides farinae. the objective of this study was to predict the b and t cell epitopes of der f 25. in the present study, we analyzed the physiochemical properties, function motifs and domains, and structural-based detailed features of der f 25 and predicted the ... | 2014 | 24895543 |
| toxicity of basil oil constituents and related compounds and the efficacy of spray formulations to dermatophagoides farinae (acari: pyroglyphidae). | pyroglyphid house dust mites are the most common cause of allergic symptoms in humans. an assessment was made of the toxicity of basil, ocimum basilicum l, essential oil, 11 basil oil constituents, seven structurally related compounds, and another 22 previously known basil oil constituents to adult american house dust mites, dermatophagoides farinae hughes. the efficacy of four experimental spray formulations containing basil oil (1, 2, 3, and 4% sprays) was also assessed. results were compared ... | 2014 | 24897858 |
| [frequency of sensitization to mites, cockroach and shrimp in adults with respiratory allergy]. | sensitization to mites and cockroach are a common cause of respiratory allergy, especially in children. there is little information about its cross-reactivity with shrimp, which is common in adult patients. | 2015 | 24915617 |
| toxicity of hiba oil constituents and spray formulations to american house dust mites and copra mites. | dermatophagoides farinae and tyrophagus putrescentiae are recognised as an important source of allergens. an assessment was made of the toxicity of hiba, thujopsis dolabrata var. hondai, oil and 13 organic compounds and the control efficacy of four experimental spray formulations containing the oil (5-30 g l(-1) spray) against both mite species. | 2015 | 24916027 |
| clearance of aspergillus fumigatus is impaired in the airway in allergic inflammation. | aspergillus fumigatus (af) sometimes colonizes and persists within the respiratory tree in some patients with asthma. to date, the precise reasons why the clearance of af is impaired in patients with asthma remain unknown. | 2014 | 24932688 |
| [the impact of subcutaneous immunotherapy with dermatophagoides farinae and dermatophagoides pteronyssinus on the quality of life of patients with allergic rhinitis and asthma]. | the prevalence of asthma and allergic rhinitis in colombia is increasing at the same rate as it is in other parts of the world. it has been determined that allergen-specific subcutaneous immunotherapy is effective in subjects with allergic rhinitis and asthma that are sensitized to house dust mites: dermatophagoides farinae and dermatophagoides pteronyssinus . | 2015 | 24967933 |
| salvia plebeia suppresses atopic dermatitis-like skin lesions. | salvia plebeia r. br. (lamiaceae) has been used for folk medicines in asian countries, including korea and china, to treat skin inflammatory diseases and asthma. in this study, we investigated the effects of s. plebeia extract (spe) on atopic dermatitis (ad)-like skin lesions and defined underlying mechanisms of action. we established an ad model in balb/c mice by repeated local exposure of house dust mite extract (dermatophagoides farinae extract, dfe) and 2,4-dinitrochlorobenzene (dncb) to the ... | 2014 | 25004886 |
| the complete mitochondrial genome of the scab mite psoroptes cuniculi (arthropoda: arachnida) provides insights into acari phylogeny. | limited available sequence information has greatly impeded population genetics, phylogenetics and systematics studies in the subclass acari (mites and ticks). mitochondrial (mt) dna is well known to provide genetic markers for investigations in these areas, but complete mt genomic data have been lacking for many acari species. herein, we present the complete mt genome of the scab mite psoroptes cuniculi. | 2014 | 25052180 |
| house dust mite sublingual immunotherapy is safe and appears to be effective in moderate, persistent asthma. | the efficacy and safety of sublingual immunotherapy in house dust mite-induced asthma have yet to be firmly established. we report the results of a double-blind, placebo-controlled, randomized clinical trial performed in mainland china. | 2014 | 25056584 |
| gene expression in the skin of dogs sensitized to the house dust mite dermatophagoides farinae. | atopic dermatitis is a multifactorial allergic skin disease in humans and dogs. genetic predisposition, immunologic hyperreactivity, a defective skin barrier, and environmental factors play a role in its pathogenesis. the aim of this study was to analyze gene expression in the skin of dogs sensitized to house dust mite antigens. skin biopsy samples were collected from six sensitized and six nonsensitized beagle dogs before and 6 hr and 24 hr after challenge using skin patches with allergen or sa ... | 2014 | 25098772 |
| two-dimensional gel proteomic analysis of dermatophagoides farinae feces. | dermatophagoides farinae fecal allergens are a major source of immunogens in home environments; however, as the source of mite fecal allergen is considered spent growth medium extract that can only mimic the pure fecal extract. in this study, we prepared and using proteomic methods analyzed a d. farinae fecal extract for the first time. the preparation approach used d. farinae feces that were produced within 8 weeks of initiating cultivation in minimized growth media. the feces were collected vi ... | 0 | 25100296 |
| generation of a chimeric dust mite hypoallergen using dna shuffling for application in allergen-specific immunotherapy. | specific immunotherapy (sit) is the only treatment that provides long lasting relief of allergy symptoms. unfortunately, sit-based traditional remedies carry the risk of producing local and/or systemic side effects. to improve the safety and efficacy of sit, it has been proposed that sit must utilize allergens that are hypoallergenic but hyperimmunogenic. therefore, we used dna shuffling to generate mutant genes encoding hypoallergens with potent immunogenicity and screened them for their capaci ... | 2014 | 25120738 |
| cow allergen (bos d2) and endotoxin concentrations are higher in the settled dust of homes proximate to industrial-scale dairy operations. | airborne contaminants produced by industrial agricultural facilities contain chemical and biological compounds that can impact the health of residents living in close proximity. settled dust can be a reservoir for these contaminants and can influence long-term exposures. in this study, we sampled the indoor- and outdoor-settled dust from 40 homes that varied in proximity to industrial-scale dairies (isd; industrial-scale dairy, a term used in this paper to describe a large dairy farm and adjacen ... | 2016 | 25138294 |
| efficacy and safety of house dust mite sublingual immunotherapy in monosensitized and polysensitized children with respiratory allergic diseases. | the efficacy of single-allergen-specific immunotherapy in polysensitized subjects is a matter of debate. this study aimed to investigate the efficacy of house dust mite (hdm) sublingual immunotherapy (slit) in monosensitized and polysensitized children. | 2014 | 25145986 |
| the gardenia jasminoides extract and its constituent, geniposide, elicit anti-allergic effects on atopic dermatitis by inhibiting histamine in vitro and in vivo. | gardenia jasminoides ellis has been used in traditional medicine for treatment of inflammation, edema, and dermaitis. the aim of this study was to investigate the mechanism by which gardenia jasminoides extract (gje) elicits anti-allergic effects in mast cells and in mice with atopic dermatitis (ad). | 2014 | 25153023 |