Publications
| Title | Abstract | Year Filter | PMID(sorted ascending) Filter |
|---|
| [campylobacter pylori (c. pylori): an occasional finding or a constant pathogenetic factor in peptic and inflammatory gastroduodenal pathology? personal observations]. | the detection of cp in the mucosa of the gastric antrum had led to the supposition of this bacterium's potential pathogenetic role in the onset and continuation of peptic ulcer and/or inflammatory gastroduodenal disease. after reviewing the literature, the authors report the incidence rate of the presence of c.p. in the mucosa of the gastric antrum in 110 symptomatic patients. endoscopic examination revealed a negative diagnosis, or the presence of gastric and/or duodenal ulcer, or aspecific inf ... | 1990 | 2280870 |
| [campylobacter pylori and the reparative processes in peptic ulcer]. | the paper deals with reparative potential of gastric and duodenal mucosa in ulcer in connection with the presence and quantity of campylobacter pylori (cp) which is found practically in all patients not only with duodenal localization of ulcer but with mediogastric and pyloroantral localization as well. no correlation between the cp presence and cp mucosa colonization on the one hand and the type of reparative processes in the mucosa is found. the presence or the absence of cp as well as the deg ... | 1990 | 2281967 |
| [helicobacter (campylobacter) pylori in the etiology and pathogenesis of gastritis and peptic ulcer]. | current information on the role of helicobacter pylori (hp) in the stomach and duodenum pathology is presented. hp is always found in active chronic gastritis and duodenal ulcer. hp damage to gastric superficial epithelium may result in the accelerated proliferation and incomplete differentiation of epithelium, this being a basis of chronic gastritis morphogenesis. factors of aggression such as hcl hypersecretion provoke a stomach metaplasia of the duodenal mucosa. hp damage to such areas combin ... | 1990 | 2281970 |
| [campylobacter pylori in patients with liver cirrhosis of different etiologies]. | the role of campylobacter pylori (cp) in the development of chronic gastritis and ulcero-erosive lesions in 76 patients with liver cirrhosis of various etiology is studied. the incidence of cp bacteriosis in liver cirrhosis was 47.3% and the incidence of cp detection by bacteriological methods was not dependent on the cirrhosis etiology. the incidence of cp detection depended on the chronic gastritis activity and the presence of ulcero-erosive lesions. hypochlorhydria is one of the important fac ... | 1990 | 2281974 |
| [chronic gastroduodenitis in children and campylobacter pylori]. | gastric biopsies from 90 children (from 5- to 15-year-old) with chronic gastroduodenitis were examined for campylobacter pylori (cp) by bacteriological, histological (giemsa stain, argentation by warthin-starry, acridine orange stain) and electron microscopical methods. cp is detected in 81.2% children. the degree of colonization was low or moderate. the increase of occurrence was noted with age and duration of disease. persistence of cp went down with the increase of atrophic change in the gast ... | 1990 | 2281975 |
| [helicobacter pylori and chronic gastritis in the gastric biopsy material in a group of randomly selected adult inhabitants of estonia]. | the occurrence of helicobacter pylori (hp) was examined in 227 subjects randomly selected among the estonian population of town kuressaare. hp was present in 166 subjects (73%). in cases of normal mucosa both in antrum and body hp was lacking. if normal gastric body mucosa was associated with antral gastritis hp was found in both regions. more often the contamination of antral and body mucosa with hp occurred in case of superficial gastritis. in subjects with atrophic gastritis the occurrence of ... | 1990 | 2281981 |
| incidence of campylobacter pylori in a consecutive series of surgical patients referred for endoscopy. | over a 9-month period, 109 consecutive patients referred from general surgical out-patient clinics for endoscopy were studied. the presenting symptoms, endoscopic diagnosis, clinical history and degree of histological gastritis were determined. the presence of the organism campylobacter pylori in oesophageal, antral and duodenal biopsies was detected by a combination of culture, histology and fluorescence microscopy. c. pylori was identified in 49.5% of patients by at least one of the methods de ... | 1990 | 2283607 |
| in vitro selection of resistant helicobacter pylori. | four strains of helicobacter pylori were subjected to an in vitro serial passage technique to compare the propensity of the organisms to develop resistance to seven classes of antibacterial agents. the passages were made on serially doubling concentrations of antibacterial agents incorporated into agar starting at one-half the base-line mic. the frequency of spontaneous resistance was also determined for each strain at four and eight times the mic of each antibacterial agent. strains resistant t ... | 1990 | 2285275 |
| [helicobacter pylori. a new species?]. | 1990 | 2287867 | |
| [monoclonal antibodies for specific immunoperoxidase detection of campylobacter pylori]. | 1990 | 2288657 | |
| [physiologic and pathologic age related changes in the stomach]. | while it would be an exaggeration to claim that the stomach does not age, age-related physiological changes are exceptions rather than the rule. in most patients, chronic gastritis is induced by helicobacter pylori, and autoimmune gastritis is rare. a specific ulcer of old age is unlikely; most ulcers in the elderly are drug-induced, with the nsaids predominating. consideration should be given to the fact that a variety of drugs may damage the mucosa, and also to the problems of drug treatment i ... | 1990 | 2289733 |
| specific cellular immune response in patients with helicobacter pylori infection. | the leukocyte migration inhibition test was performed in 39 patients with helicobacter pylori infection and in 38 patients without such infection. the culture of helicobacter pylori was used as antigen. a highly significant inhibitory effect on leukocyte migration was found in patients with helicobacter pylori infection. the results can be taken as proof of a systemic immune response to helicobacters at the cellular level in patients with helicobacter pylori infection. | 1990 | 2289778 |
| [helicobacter pylori and b-gastritis: nonspecific and specific immune mechanisms]. | 1990 | 2290791 | |
| presence of helicobacter pylori in patients with non-ulcer dyspepsia revealing normal antral histological characteristics. | two hundred consecutive patients suffering from non-ulcer dyspepsia were studied for the presence of helicobacter pylori in antral gastritis and normal antral mucosa, using the combination of culture, modified giemsa stain and a sensitive immunoperoxidase stain as means of detection. h. pylori gastritis was present in 56% of the cases. the bacterium was present in 75% of cases of normal antral mucosa, however, in low numbers. it is concluded that 87% of patients with non-ulcer dyspepsia are h. p ... | 1990 | 2292346 |
| peptic ulcer, noxious stress, and campylobacter pylori. | 1990 | 2293595 | |
| campylobacter pylori colonizing heterotopic gastric tissue in the rectum. | campylobacter pylori specifically attaches to gastric epithelial cells and is the etiologic agent for type b gastritis. the authors report the case of a woman with the rare finding of heterotopic gastric mucosa in the rectum that was colonized with c. pylori. histologic findings of the heterotopic mucosa revealed active chronic gastritis that resolved when c. pylori was eradicated with bismuth subsalicylate and antibiotics. this is the first report of c. pylori in a location distal to the duoden ... | 1990 | 2294694 |
| lymphocytic gastritis in patients with celiac sprue or spruelike intestinal disease. | a distinctive form of gastritis, characterized by lymphocytic infiltration of pit epithelium, has recently been described in association with evidence of campylobacter pylori infection. we have evaluated simultaneous small bowel and gastric biopsies from 22 patients with diarrhea or malabsorption, all of which showed small bowel changes characteristic of sprue or spruelike disease. in 10 of 22 patients, striking lymphocytic gastritis was identified. cases positive for lymphocytic gastritis had a ... | 1990 | 2295386 |
| duodenal ultrastructure in patients with chronic renal failure with a comment on the incidence of campylobacter pylori infection. | this study was aimed at identifying ultrastructural abnormalities that may be present in the duodenum of patients with chronic renal failure who were undergoing hemodialysis and that may have an effect on the normal absorptive function of the duodenum. duodenal biopsy specimens from ten patients and four controls were examined. light microscopy showed gastric metaplasia in eight patients and in none of the controls. the main electron microscopic findings were related to the metaplastic changes, ... | 1990 | 2296800 |
| gastric mucosal prostaglandin synthesis in the presence of campylobacter pylori in patients with gastric ulcers and non-ulcer dyspepsia. | it is unclear how campylobacter pylori (cp) interacts with gastric mucosal prostaglandins (pg). in a double-blind study we measured gastric pg synthesis in 22 patients with benign gastric antral ulcers (gu) and 26 with non-ulcer dyspepsis (nud). cp status was determined by histology and bacteriology: 26 (16 gu plus 10 nud) were cp positive, and 22 (6 gu plus 16 nud) were cp negative. patients with severe gastritis regardless of cp status) had significantly higher pge2 and pgi2 values than those ... | 1990 | 2296963 |
| increased blood leukocytes in patients with campylobacter pylori. | 1990 | 2297198 | |
| natural competence for genetic transformation in campylobacter pylori. | 1990 | 2299221 | |
| the origins of helicobacter (campylobacter) pylori. | 1990 | 2300036 | |
| intrafamilial clustering of helicobacter pylori infection. | colonization of the gastric antrum by helicobacter pylori (formerly campylobacter pylori) has been associated with primary gastritis. we determined the frequency of colonization by h. pylori in gastric-antrum biopsy specimens from 93 children undergoing gastroscopy for the evaluation of upper gastrointestinal symptoms. we also determined h. pylori igg antibody levels by enzyme-linked immunosorbent assay in coded serum samples from these children, family members, and control subjects of comparabl ... | 1990 | 2300088 |
| [antibiotic therapy and campylobacter pylori]. | 1990 | 2302995 | |
| does helicobacter pylori colonize the gastric mucosa of meckel's diverticulum? | helicobacter pylori (formerly, campylobacter pylori) is a highly adapted organism that seems to infect only gastric-type mucosa. in this study, we attempted to determine whether gastric epithelium at a site distant from the stomach, the heterotopic gastric mucosa of meckel's diverticulum, was susceptible to colonization by h. pylori. retrospectively, we examined biopsy specimens from 23 patients who had undergone resection of meckel's diverticulum that contained heterotopic gastric mucosa. as a ... | 1990 | 2304363 |
| characterization of and human serologic response to proteins in helicobacter pylori broth culture supernatants with vacuolizing cytotoxin activity. | helicobacter pylori infection is strongly associated with histologic gastritis and peptic ulcer disease. broth culture supernatants from a subset of h. pylori strains induce vacuolization in cultured cells, a phenomenon that has been attributed to cytotoxin activity. concentrated culture supernatants from 15 of 28 (53.6%) h. pylori strains tested induced vacuolization in hela cells in titers ranging from 1:10 to 1:180. sodium dodecyl sulfate-polyacrylamide gel electrophoresis and silver staining ... | 1990 | 2307514 |
| [evaluation of agar media for growth of campylobacter pylori]. | the supporting ability for the growth of campylobacter pylori was tested on various agar plates. c. pylori grew on media supplemented with blood, serum or egg-yolk, and it showed good growth on mueller hinton agar with horse blood, and on brain-heart infusion agar with yeast extract and horse blood. the organism grew moderately on mueller hinton agar, but could not grow on the other unsupplemented media. mueller hinton medium may be of use as a proper base of blood agar for growth of c. pylori. ... | 1990 | 2308216 |
| [13c-urea breath test as a non-invasive method for the detection of helicobacter (campylobacter) pylori]. | the 13c-urea breath test was used for diagnosing noninvasively the possible presence of helicobacter (formerly called campylobacter) pylori in 20 patients with dyspepsia (ten men and ten women, mean age 40.2 [24-74] years). h. pylori was cultured from 14 patients, while in six the culture was negative. the proportion of 13c in expired air was measured by isotope mass-spectrometer and expressed as delta (basal value about 20%). a dose of 2.5 mg urea per kg body-weight (bw) was ingested after a st ... | 1990 | 2311511 |
| bacterial adhesion and disease activity in helicobacter associated chronic gastritis. | ultrastructural examination of biopsies showing helicobacter pylori associated chronic gastritis reveals close attachment between gastric surface epithelial cells and the organism. the finding of 'adhesion pedestals', which represents a cellular response to the presence of the organism, is analogous to the response of intestinal cells to enteropathogenic e coli. thus the development of bacterial attachment sites in h pylori associated gastritis might be an indication of pathogenicity. we have th ... | 1990 | 2311970 |
| tightly spiral shaped bacteria in the human stomach: another cause of active chronic gastritis? | tightly spiral shaped gram negative bacteria were seen in the gastric biopsies obtained from two patients undergoing gastroscopy. active chronic gastritis was present in both patients and one patient also had gastric ulceration. attempts to culture the organism by a number of methods were unsuccessful but positive urease results were obtained in both patients. both patients were treated with colloidal bismuth subcitrate. biopsies taken after treatment showed resolution of infection and histologi ... | 1990 | 2311971 |
| helicobacter pylori infection in meckel's diverticula. | 1990 | 2311989 | |
| the role of campylobacter (helicobacter) pylori in disorders of the gastrointestinal tract. | to evaluate the role of campylobacter pylori in different gastrointestinal disorders, serum igg antibodies against c. pylori were determined in dyspeptic patients and in a control group of healthy children and adults. twenty-eight percent of the dyspeptic patients with normal mucosa were seropositive. among the patients with altered mucosa, the seroprevalence increased from duodenitis (48%) to gastritis (89%) and gastric or duodenal ulcer, gastric stump gastritis and carcinoma (100%, for each gr ... | 1990 | 2312173 |
| campylobacter pylori in the upper gastrointestinal tract of patients with hiv-1 infection. | fifty one patients with human immuno-deficiency virus (hiv-1) infection who had been consecutively endoscoped for upper gastrointestinal symptoms were biopsied (stomach or duodenum, or both) and compared with 59 age and sex matched controls for the presence of campylobacter pylori. in 28 (47%) of the control group but in only seven (14%) of the hiv seropositive patients were c pylori seen on histological examination (p less than 0.001, odds ratio 5.6, 95% confidence interval 2.2-14.5). sixteen p ... | 1990 | 2312753 |
| distribution of campylobacter pylori in the upper and lower gastrointestinal tract: a microbiological and histological study. | 1990 | 2312755 | |
| patient-to-patient transmission of campylobacter pylori infection by fiberoptic gastroduodenoscopy and biopsy. | three instances of subclinical reinfection with campylobacter pylori were observed in two successfully treated patients during follow-up of c. pylori gastritis. the reinfections occurred 1 month and 21 months (patient 1) and 32 months (patient 2) after the completion of antibacterial treatment. sequential measurement by elisa of serum igg antibody levels to the microorganism showed a significant increase in two of the three instances of reinfection. patient-to-patient transmission was proved by ... | 1990 | 2313129 |
| campylobacter pylori and reflux oesophagitis. | 1990 | 2316352 | |
| helicobacter pylori in gambian children with chronic diarrhoea and malnutrition. | infection with helicobacter pylori (formerly campylobacter pylori) was studied by measuring antibody titres to h pylori in gambian children. serological evidence of infection was found in 12 of 82 (15%) infants aged less than 20 months; this increased to 62 of 135 (46%) in those aged 40-60 months. positive serology was found in 41 of 77 (53%) infants with chronic diarrhoea and malnutrition (mean age 19 months, range 5-36) compared with 18 of 70 (26%) of age matched healthy controls and nearly a ... | 1990 | 2317065 |
| possible evidence of invasiveness of helicobacter (campylobacter) pylori. | gastric/duodenal biopsy material from 52 patients was examined immunohistochemically for helicobacter (campylobacter) pylori. specimens from 34 of the patients harboured helicobacter pylori along the mucosal surface and 13 of these featured, in addition, immunopositive material within the lamina propria. the remaining 18 biopsies were non-reactive. this observation suggests that helicobacter pylori can penetrate the epithelium and its basement membrane, resulting in the production of specific sy ... | 1990 | 2318218 |
| purification and n-terminal analysis of urease from helicobacter pylori. | urease of helicobacter pylori (formerly campylobacter pylori) is believed to represent a critical virulence determinant for this species. ammonia generated by hydrolysis of urea may protect the acid-sensitive bacterium as it colonizes human gastric mucosa. an h. pylori strain, cultured from a gastric biopsy of a patient with complaints of abdominal pain and a history of peptic ulcer disease, was isolated on selective medium and cultured in mueller-hinton broth supplemented with 4% fetal calf ser ... | 1990 | 2318539 |
| lack of in vitro activity of omeprazole against campylobacter pylori. | 1990 | 2318995 | |
| [the course of benign stomach ulcer; results of a follow-up study]. | a follow-up investigation was conducted in 112 patients in whom a benign gastric ulcer had been found endoscopically between 1978 and 1984. nine patients had been operated upon, mainly in the earlier years. out of 65 patients ultimately selected for the study 38 underwent gastroscopy and 35 could be evaluated. of these 21 (60%) had complaints and another 60% used intermittent or continuous medication because of complaints referred to the stomach. in 15 patients erosions (4) or benign gastric ulc ... | 1990 | 2320168 |
| [the urease rapid test (clo test). attempt at statistical analysis for the evaluation of campylobacter colonization in the gastric antrum]. | clo-tests: a statistical analysis for the evaluation of the presence of campylobacter pylori in antral mucosal biopsies. antral biopsies taken in a sample of 475 endoscopy patients were positive for clo on 21% of 77 controls, compared with 39% of non-ulcer dyspepsia (nud) patients without and 69% with a history of former peptic ulcer. epigastric pain was associated with a positive clo-test more frequently than belching or heart burn. patients with nud of turkish or yugoslavian nationality had a ... | 1990 | 2320813 |
| [ulcer symptoms without demonstration of ulcer: causative therapy with demonstration of helicobacter pylori]. | helicobacter pylori-associated gastritis was found by endoscopy in 15 (= 28%) out of 53 patients presenting gastric pain of ulcer type without macroscopically detectable lesion of the gastric mucosa. following a treatment of four weeks with bismuth subcitrate tablets (2 x 2 tablets daily), in 73% improvement of histological findings and in 87% elimination of bacteria could be attained. thus, this causal therapy had a favourable effect on patient complaints. | 1990 | 2320815 |
| [helicobacter pylori infection among employees at the gastroenterologic section, haukeland hospital]. | using the c-14 urea breath test we estimated the gastric urease activity among 46 healthy norwegians, all employed at the section of gastroenterology, haukeland hospital, norway. the overall prevalence of helicobacter pylori-infection (30.4%) is similar to that reported previously among healthy subjects outside hospitals. the tendency towards higher prevalence among the gastroenterologists (41.7%) may be accounted for partly by the preponderance of males in this profession. the results do not su ... | 1990 | 2321194 |
| cytologic diagnosis of campylobacter pylori-associated gastritis. | forty-nine paired gastric brushings and biopsy specimens were reviewed to determine the cytologic presentation of campylobacter pylori-associated gastritis. the bacterium was identified in ten routinely prepared cytologic specimens, seven of which were positive for c pylori by biopsy. c pylori could be readily distinguished from other bacteria and was accompanied by inflammation and reparative atypia of gastric epithelial cells. gastric brushing cytology is an effective method of diagnosing c py ... | 1990 | 2321452 |
| [campylobacter pylori in patients with gastroduodenal disease]. | recent advances of campylobacter pylori (c. pylori) in human gastric disease and peptic ulcer were reviewed. c. pylori is a microaerophilic, motile, gram negative spiral rod bacterium. and all strains of c. pylori has a strong urease activity. in our experience. 91% of duodenal ulcer, 88% of gastric ulcer and 43% of control have c. pylori associated gastric mucosa. patients of peptic ulcer with c. pylori infection were high relapse than patients of peptic ulcer without c. pylori, c. pylori is no ... | 1990 | 2321983 |
| surface hydrophobicity of gastric mucosa in peptic ulcer disease. relationship to gastritis and campylobacter pylori infection. | the hydrophobicity of biopsy specimens of gastric mucosa in 228 dyspeptic subjects undergoing diagnostic endoscopy was assessed by measuring the plateau-advancing contact angle of saline drops using a goniometer. subjects with duodenal ulcers (n = 49) and gastric ulcers (n = 17) had significantly lower mean contact angles than controls (n = 124) without ulcer (57 degrees in duodenal ulcer, 59 degrees in gastric ulcer vs. 66 degrees in controls; p less than 0.0001). there was no change in contact ... | 1990 | 2323518 |
| genotypical variation of campylobacter pylori from gastric mucosa. | in a previous study, the recurrence of the campylobacter pylori infection after apparently successful antibacterial therapy was determined to be due to recrudescence rather than reinfection. although the dna patterns of pre- and posttreatment isolates were very similar, we detected minor differences between the two patterns in about one third of the patients. these differences were not artifacts, but originated in the coexistence in the stomach of (sub)populations of bacteria with slightly diffe ... | 1990 | 2324277 |
| rapid endoscopy room diagnosis of campylobacter pylori-associated gastritis in children. | a modified urease broth test was used in 109 gastric biopsy specimens of children that yielded a 96% sensitivity and a 100% specificity rate for campylobacter pylori infection. the longest reaction time was less than or equal to 4 min. the correlation between the degree of c. pylori infection and the reaction time was found to be highly significant (gamma = 0.78, p less than 0.001). patients were examined as outpatients, and immediate medications were prescribed for eradication of the bacteria o ... | 1990 | 2324897 |
| nucleotide sequence of two genes from helicobacter pylori encoding for urease subunits. | 1990 | 2326167 | |
| ablation of exaggerated meal-stimulated gastrin release in duodenal ulcer patients after clearance of helicobacter (campylobacter) pylori infection. | an exaggerated increase in meal-stimulated gastrin is a common finding in patients with duodenal ulcer. duodenal ulcer patients also exhibit an increase in the number of parietal cells, which results in an increase in maximum acid output. there are also data to suggest that acid hypersecretion may not predate the ulcer disease, but is acquired, possibly due to the trophic effects of the exaggerated gastrin release on parietal cells. we investigated meal-stimulated gastrin release in nine helicob ... | 1990 | 2327380 |
| 14c-urea breath test for the detection of helicobacter pylori. | the high urease activity of helicobacter pylori can be used to detect this bacterium by noninvasive breath tests. we have developed a 14c-urea breath test which uses 5 microci 14c with 50 mg nonradioactive urea. breath samples are collected at baseline and every 30 min for 2 h. our study compared the outcome of the breath test to the results of histology and culture of endoscopically obtained gastric biopsies in 84 patients. the breath test discriminated well between the 50 positive patients and ... | 1990 | 2327381 |
| guinea pig model for antibiotic transport across gastric mucosa: inhibitory tissue concentrations of clindamycin against helicobacter pylori (campylobacter pylori) following two separate dose regimens. | an animal model for antibiotic secretion across gastric mucosa was developed using adult guinea pigs. antibiotics were given intramuscularly, and levels in serum and gastric mucosa were measured by high-pressure liquid chromatography at 1, 2, 4, 6, and 8 h postinjection. mucosal levels of the drugs were measured in the superficial luminal portion of the mucosa, which was removed by mechanical scraping. clindamycin levels were measured after doses of 10 and 100 mg/kg of body weight. after doses o ... | 1990 | 2327758 |
| prevalence of campylobacter pylori in a tertiary care hospital in the mid-atlantic united states. | 1990 | 2331197 | |
| helicobacter pylori and protein losing enteropathy. | 1990 | 2334217 | |
| [the characteristics of the clinical course of long-term nonhealing duodenal ulcers combined with chronic gastric erosion and the treatment of patients with the given pathology]. | the authors provide data on the follow-up and treatment of 76 patients with slow in healing ulcers and chronic erosions. in patients with associated pathology, the clinical course of the disease is marked by a steady painful syndrome that occurs 1 to 1.5 h after meal. in the presence of campylobacter pyloridis in these patients, the treatment schedule is to include de-nol and the concentrate of granulocytes. the use of local administration of the concentrate of granulocytes combined with hyperba ... | 1990 | 2336624 |
| [campylobacter pylori, its detection and association with common pathologic conditions of the gastro-duodenum]. | the authors evaluate clinical experience based on a correlation between the clinical condition and the finding of campylobacter pylori (cp) in a total of 1027 specimens of the gastric mucosa. they confirmed the high incidence of cp in patients with a fresh duodenal ulcer (g 7%) but also in the inactive stage of duodenal ulcer disease (97.8%) and in patients with a pyloric ulcer (94.4%). an analogous incidence of cp in patients with so-called isolated duodenitis (in the course of the disease no u ... | 1990 | 2336815 |
| [the site of recurrent ulcer following stomach surgery (billroth i and ii)]. | in 69 patients with recidivation ulcer after an operation of the stomach (51 times billroth ii and 18 times billroth i) was investigated whether or not there are differences in the localisation of an ulcer. in patients operated on according to billroth ii ulcers of the anastomoses are dominating, whereas in patients operated on according to billroth i the majority of ulcers is to be found in the residual stomach. the causes for the deviating distribution pattern are not unequivocal. changed diag ... | 1990 | 2336868 |
| helicobacter pylori-associated upper gastrointestinal disease in saudi arabia: a pathologic evaluation of 298 endoscopic biopsies from 201 consecutive patients. | in a prospective study, histopathological examination 298 upper gastrointestinal (ugi) biopsies, obtained from 201 consecutive patients, was made. patients were referred with mild to severe dyspeptic symptoms. the aim of the study was to compare the rate of identification of helicobacter pylori (h. pylori) in the histologically normal gastric mucosa with that in histologically confirmed gastritis or peptic ulcer disease. the gastroduodenal mucosa was histologically normal in 35 patients (17.4%); ... | 1990 | 2337055 |
| [workshop gastroduodenal pathology and campylobacter pylori. second meeting of the european campylobacter pylori study group]. | 1990 | 2338390 | |
| [semiquantitative culture of campylobacter pylori in gastroduodenal disorder]. | results of semiquantitative culture of the gastric mucosa for campylobacter pylori (c. pylori) are reported. the samples were obtained by biopsy at the pyloric antrum along the lesser curvature from 197 patients with various gastric or duodenal disorders. 1) c. pylori was found in most cases with duodenal ulcer (100%), gastric ulcer (87.7%) and acute gastric mucosal lesion (agml) (87.5%). relatively heavy infestation was usual in these diseases, while relatively small amounts of the organism wer ... | 1990 | 2338503 |
| inoculation of barrier-born pigs with helicobacter pylori: a useful animal model for gastritis type b. | at the age of 8 weeks, 15 barrier-born pigs, specific pathogen free, were inoculated intragastrically with suspensions of 10(7) to 10(10) cfu of helicobacter pylori after pretreatment with omeprazole. the pigs were observed for up to 12 weeks, endoscopic biopsy specimens were taken, and serum samples were drawn. h. pylori was identified by routine culturing and by staining with an h. pylori-specific monoclonal antibody on cryostat sections of gastric biopsy specimens. in 11 of 15 inoculated pigs ... | 1990 | 2341177 |
| helicobacter pylori urease activity is toxic to human gastric epithelial cells. | a human gastric adenocarcinoma cell line was used to evaluate the contribution of urease from helicobacter (formerly campylobacter) pylori to its cytotoxicity. gastric cells cultured in medium supplemented with 20 mm urea were exposed to 5 x 10(6) cfu of h. pylori per ml with or without the addition of a urease inhibitor, acetohydroxamic acid. viabilities of cells exposed to h. pylori for 2, 24, and 48 h, assessed by incorporation of neutral red dye, were 60, 27, and 16%, respectively; however, ... | 1990 | 2341188 |
| helicobacter pylori and the italian general practitioners. | 1990 | 2344917 | |
| helicobacter pylori gastritis: a 'normal' phenomenon. | 1990 | 2344934 | |
| evaluation of different methods for detection of helicobacter pylori in patients with gastric disease. | endoscopic gastric antral biopsy specimens (133) from 92 dyspeptic patients with endoscopically evident gastritis (34; including one patient with dual pathology) gastric ulcer (13), duodenitis (17; including one patient with dual pathology) duodenal ulcer (29) and 41 subjects of non ulcer dyspepsia (nud) with endoscopically normal upper gastrointestinal tract were examined for h. pylori by stained smear, various urease tests, culture and histopathology. crushed tissue smear stained by gram's met ... | 1990 | 2345021 |
| seroprevalence of helicobacter pylori infections in thailand. | serologic studies in developed countries indicate that helicobacter (formerly campylobacter) pylori infection is uncommon until the third decade of life and achieves a peak prevalence of 50% in the seventh decade. in developing countries the epidemiology of h. pylori has not well been described. a sensitive and specific serologic assay for h. pylori infection was validated in thai patients also studied by culture and histologic examination of biopsy specimens. the prevalence of h. pylori antibod ... | 1990 | 2345304 |
| persistence of helicobacter pylori in conventionalized piglets. | gnotobiotic piglets were challenged at 3 days of age with helicobacter (campylobacter) pylori and then transferred to conventional housing at 24 days of age. piglets were sacrificed 43-45, 57-60, and 87-90 days after challenge. h. pylori was recovered from the stomachs of all piglets challenged except for two piglets sacrificed 45 days after challenge. h. pylori was not recovered from uninfected control piglets. in addition to h. pylori, lactobacillus and bacillus species were recovered from con ... | 1990 | 2345307 |
| intracellular vacuolization caused by the urease of helicobacter pylori. | tissue culture cells were exposed to supernatants of helicobacter pylori for 24 h at 37 degrees c in the presence of various quantities of urea. in the normal human stomach the concentration of urea is less than or equal to 4 mmol/l, and in the presence of this low concentration up to 10% of vero cells showed intracellular vacuolization. in the presence of 7.5 mmol/l urea, 25% of the cells showed vacuolization. with 30 mmol/l urea, the final ph was 7.6, indicating that vacuolization was not due ... | 1990 | 2345308 |
| inappropriate hypergastrinaemia in asymptomatic healthy subjects infected with helicobacter pylori. | an elisa test determined serologically that eight of 95 apparently healthy men (aged 19-26 years) had an asymptomatic infection with helicobacter pylori at the time of simultaneous measurement of 24 hour intragastric acidity and 24 hour plasma gastrin concentration. there was no significant difference in the median integrated 24 hour intragastric acidity between the h. pylori positive and h. pylori negative subjects (688 and 842 mmol/h/l; p = 0.271, respectively), whereas the median integrated 2 ... | 1990 | 2351302 |
| unusual fatty acid substitution in lipids and lipopolysaccharides of helicobacter pylori. | cellular fatty acids, phospholipid fatty acids, and lipopolysaccharide fatty acids of four strains of helicobacter pylori were analyzed by gas-liquid chromatography. the presence of myristic acid, palmitic acid, stearic acid, oleic acid, linoleic acid, 19-carbon cyclopropane fatty acid, beta-hydroxypalmitic acid, and beta-hydroxystearic acid was confirmed. in phospholipids, myristic acid and 19-carbon cyclopropane fatty acid were the major fatty acids. hydroxy fatty acids and unsaturated fatty a ... | 1990 | 2351736 |
| campylobacter gastritis simulating menetrier's disease by upper gastrointestinal radiography. | within this decade it has been determined that primary gastritis in both children and adults is frequently associated with infection of the gastric mucosa with campylobacter pylori. it is characterized by a chronic inflammatory process in which the mucosa of the gastric antrum is typically most severely involved. other regions of the stomach may be involved and associated peptic ulcers of the stomach and duodenal bulb are frequent. a case of c. pylori gastritis is reported in which involvement o ... | 1990 | 2352802 |
| endoscopy in dyspeptic patients: is gastric mucosal biopsy useful? | should dyspeptic patients coming to endoscopy with "normal" findings also be biopsied? to assess this, we studied the sensitivity and specificity of endoscopic examination compared with histology, microscopic evidence of helicobacter pylori, cp-test, culture, and serum igg and iga antibody titers to h. pylori to determine whether endoscopy and antral biopsies really are useful. one hundred seven consecutive dyspeptic patients (mean age 43 yr) were entered. four antral biopsies were taken routine ... | 1990 | 2353689 |
| opsonic activity of specific human igg against helicobacter pylori. | there is a strong association between chronic gastroduodenal disease in adults and children and the recovery of helicobacter pylori (formerly campylobacter pylori) from gastric biopsy specimens. however, data relevant to host defense mechanisms directed against this organism are scarce. the ability of h. pylori-specific antibody and complement to enhance the in vitro phagocytosis and killing of h. pylori by human peripheral blood polymorphonuclear leukocytes (pmnl) were studied. sera with igg an ... | 1990 | 2355192 |
| bacteriophages in helicobacter (campylobacter) pylori. | bacteriophages in different stages of maturation were found in thin sections of a clinical isolate of helicobacter (campylobacter) pylori. mature phage heads measured 70 x 60 nm and the tail at least 120 nm. lysogeny was maintained during subculture on blood agar for more than 3 months after isolation from a gastric biopsy. | 1990 | 2355390 |
| the prevalence of anti-helicobacter (campylobacter) pylori antibodies in patients and healthy blood donors. | an enzyme linked immunosorbent assay (elisa) with a sonicated suspension of helicobacter (campylobacter) pylori as antigen was used to detect anti-h. pylori antibodies in 517 patients without dyspepsia or peptic ulcer symptoms and 401 healthy blood donors. the criterion of seropositivity was determined from a receiver operating curve computed with the values of optical densities of 48 sera from dyspeptic patients with proven helicobacter-associated gastritis and 16 sera from dyspeptic patients w ... | 1990 | 2355391 |
| [diagnosis of campylobacter pylori infection of the gastric mucosa: histologic and microbiologic aspects]. | the usefulness of culturing gastric biopsies obtained by endoscopic visualization, gram stain, immediate and late urease test, and histologic observation of campylobacter pylori in the diagnosis of gastric mucosa infection by campylobacter pylori was assessed in 75 patients. four antral biopsies were obtained in 75 patients, 35 with duodenal ulcer and 40 with nonulcerous dyspepsia and all specimens were subjected to the above procedures. positive criteria for infection were either a positive cul ... | 1990 | 2355777 |
| inability of human clinical strains of helicobacter pylori to colonize the alimentary tract of germfree rodents. | several attempts were made to colonize the alimentary tract and infect germfree balb/c mice and germfree sprague-dawley rats with two human isolates of helicobacter pylori. the alimentary tracts of mice, sacrificed at intervals between 1 day and 20 weeks after oral challenge, were culture negative for h. pylori. the alimentary tract, kidney, liver, and mesenteric lymph nodes were culture negative for h. pylori 5 h after intravenous challenge. growth of h. pylori was inhibited by homogenates of m ... | 1990 | 2357642 |
| helicobacter (campylobacter) pylori infestation and the development and progression of chronic gastritis: results of long-term follow-up examinations of a random sample. | one hundred and thirty-nine subjects representing a randomly selected sample of an estonian urban population examined endoscopically, bioptically and bacteriologically in 1979 was re-examined in 1985. in the antrum the development of superficial gastritis was clearly associated with the appearance or persistence of helicobacter pylori (hp) infestation. the further progression of superficial gastritis could less clearly be related to hp infestation, although regression and progression of antral s ... | 1990 | 2357934 |
| helicobacter pylori is not identified in areas of gastric metaplasia of gall bladder. | sections from 200 cholecystectomy specimens were searched microscopically for areas of gastric metaplasia and helicobacter (campylobacter) pylori colonization. the presence of gastric metaplasia was confirmed in 31 cases by the presence of tall columnar cells with abundant apical neutral mucin. examination of haematoxylin and eosin and, in some cases, warthin-starry stained sections failed to demonstrate h. pylori in any of these 31 cases or in 29 other cases with 'bladder neck-type mucous gland ... | 1990 | 2358970 |
| [the role of campylobacter pylori in gastroduodenal pathology]. | biopsy specimens from the gastric antral mucosa of 194 patients with upper gastrointestinal symptoms were studied with the warthin-starry silver stain to demonstrate the presence of campylobacter pylori (cp). of these patients, 44 had peptic ulcer visible on endoscopic investigation. spiral bacteria were detected in 70 out of 75 specimens with histologically active gastritis (93%), in 34 of 54 specimens with inactive form of gastritis (63%) and in 26 of 65 specimens without morphological changes ... | 1990 | 2359867 |
| suppression of gastric urease activity by antacids. | campylobacter pylori (cp) infection among healthy employees at the section of gastroenterology was studied by means of the carbon-14 urea breath test. fourteen of 46 individuals (30.4%) were infected with campylobacter pylori (cp+). eleven cp+ individuals were treated with a low-dose regimen of antacids (four tablets a day) for 2 weeks. the 14c recovery dropped from 8.36 +/- 1.26% before treatment to 5.70 +/- 1.24% (p = 0.023) approximately 12 h after the last intake of antacids, a 31.8% reducti ... | 1990 | 2359978 |
| [helicobacter pylori is a globally spread bacterium causing gastritis in man]. | 1990 | 2362499 | |
| duodenal bulb biopsy findings for patients with non-ulcer dyspepsia with or without campylobacter pylori gastritis. | duodenal bulb biopsy specimens from 85 patients with non-ulcer dyspepsia (30 of whom had normal stomachs and 52 of whom had campylobacter pylori gastritis) were examined for the presence and amount of gastric surface epithelial metaplasia (using both the hematoxylin and eosin stain and the alcian blue-periodic acid-schiff method), acute inflammation, and c. pylori (using the giemsa stain). gastric metaplasia occurred in the duodenal bulb in 61% of patients with gastric c. pylori and in an identi ... | 1990 | 2362937 |
| effect of bismuth subcarbonate against campylobacter pylori: do citrate ions improve antibacterial activity? | the minimum inhibitory concentrations of three bismuth subcarbonate preparations: 1. bismuth subcarbonate, 2. a mixture of 50% bismuth subcarbonate and 50% citric acid, 3. a mixture of 50% bismuth subcarbonate and 50% potassium citrate were assayed against 30 strains of campylobacter pylori employing the agar dilution method. bismuth subcarbonate alone exhibited an mic50 of 2 mg/l and was more effective than the two combinations (mic50 4 mg/l). it is concluded that the addition of citrate ions d ... | 1990 | 2363796 |
| [14c]urea breath test for diagnosis of helicobacter pylori. | h. pylori is a potent urease producer, a characteristic that has been exploited in the development of the [14c]- and [13c]urea breath tests. the prevalence of h. pylori infection also is known to increase with advancing age; however, the individual patient's age has not routinely been considered when interpreting urea breath test results. the aim of this study was to validate a short, age-adjusted [14c]urea breath test for use in diagnosing h. pylori infections. forty-one subjects (28 volunteers ... | 1990 | 2364842 |
| helicobacter mustelae-associated gastritis in ferrets. an animal model of helicobacter pylori gastritis in humans. | gastric helicobacter mustelae was present in 100% of 11 adult female ferrets (mustela putorius furo). the high immunoglobulin g antibody levels to h. mustelae in all ferrets showed a significant immune response to the organism. urease mapping of the ferret stomach indicated that the bacteria heavily colonized the proximal duodenum and antrum and, to a lesser extent, the corpus. the histological gastritis observed coincided with presence of h. mustelae. superficial gastritis was noted in the oxyn ... | 1990 | 2365188 |
| helicobacter pylori (campylobacter pylori) and duodenal ulcer. | 1990 | 2366700 | |
| iron deficiency in helicobacter (campylobacter) pylori. | 1990 | 2369445 | |
| helicobacter pylori gastric infection in gnotobiotic beagle dogs. | establishment of infection with helicobacter pylori and gastritis in nonhuman species is currently only successful in gnotobiotic piglets. this study was designed to determine whether h. pylori will colonize the gastrointestinal tract of gnotobiotic dogs. gnotobiotic beagle pups were derived by standard methods. group a (five dogs) was orally challenged with 3 x 10(8) h. pylori at 7 days of age. group b (two dogs) received only peptone water but was contact-exposed beginning on day 23 postinfect ... | 1990 | 2370111 |
| antral helicobacter pylori in patients with chronic renal failure. | patients with chronic renal failure who were undergoing dialysis were recently shown to have a low prevalence of duodenal helicobacter (campylobacter) pylori colonisation in spite of a high incidence of gastric metaplasia. the prevalence of the organism in the gastric antrum of 50 similar patients was estimated and compared with that in a control group comprising 120 consecutive patients with no renal failure who were being investigated for a variety of symptoms and signs related to the upper al ... | 1990 | 2370308 |
| ultrastructural study of helicobacter pylori-associated gastritis. | endoscopic biopsies of antral mucosa from 26 patients with helicobacter pylori-associated gastritis were studied by electron microscopy (em). scanning electron microscopy (sem) showed clustering of h. pylori in the intercellular areas, being entrapped by the microvilli which were decreased at the sites where the bacilli were seen. the observations of sem were confirmed by transmission electron microscopy (tem), which showed adherence of the bacilli to the cell surface, producing cup-shaped depre ... | 1990 | 2370600 |
| the gastric juice urea and ammonia levels in patients with campylobacter pylori. | the authors studied gastric juice ammonia and urea nitrogen levels to determine how they are altered by gastric campylobacter pylori (cp) infection. patients with chronic gastritis (20), peptic ulcer (24), hepatic cirrhosis (10), chronic renal failure (13), or gastric remnant (20) were included. endoscopic biopsy specimens stained with the warthin-starry stain were evaluated for the presence of cp. blood and gastric juice analysis was performed for 11 of the patients with chronic renal failure a ... | 1990 | 2371972 |
| helicobacter pylori-like microorganisms and chronic active gastritis in ferrets. | to determine the prevalence and histology of helicobacter pylori (hp) associated gastritis in young ferrets, we examined 36 normal 2- to 4-month old ferrets. identification of hp-like microorganisms included warthin starry stains of tissue sections, rapid urease test on fresh tissue, and culture. hp-like microorganisms were found in the stomachs of 35/36 ferrets. the highest density of microorganisms was seen in the antrum, where hp-like microorganisms were present in the pits and in deep glands ... | 1990 | 2371981 |
| helicobacter pylori and gastritis in peruvian patients: relationship to socioeconomic level, age, and sex. the gastrointestinal physiology working group. | studies in 1,120 peruvian adults suffering from upper gastrointestinal symptoms and stratified according to socioeconomic level, age, and sex have shown the following: rates of helicobacter pylori infection range from 3% in patients with normal gastric mucosa to 92% in cases of chronic active gastritis. age-specific infection rates do not vary with the severity of active gastritis and are similar in men from low and high socioeconomic levels. women from higher socioeconomic backgrounds show a si ... | 1990 | 2371982 |
| aggressive factors or altered protective capacity of the gastric mucosa in chronic liver disease. | this study was conducted to assess the behavior of various parameters involved in mucosal protection (mucus and prostaglandins) and of presumed aggressive factors (hydrochloric acid and helicobacter (campylobacter) pylori in 20 patients with chronic liver disease, with or without clinical and instrumental signs of portal hypertension. the two groups of patients showed no difference from controls with respect to gastric acid secretion and the presence of antral helicobacter pylori. the amount of ... | 1990 | 2373469 |
| evaluation of a modified medium for the one hour urease test for helicobacter pylori infection. | the biopsy urease test is a simple and rapid method for the diagnosis of helicobacter pylori infection; results are obtained within 4 h to 24 h. various modifications of the media used in this test have been tried, to improve the accuracy and speed of the test. we compared the yield obtained with two media: the standard christensen's urea medium and a modified plain urea medium (without the nutrients glucose and peptone); the result was read upto 1 h. in the first 53 cases, culture was obtained ... | 1990 | 2373533 |
| [isolation of campylobacter pylori]. | a total of 424 patients with gastroduodenal ulcers were examined. spot biopsy specimens of gastroduodenal tissue were examined by histologic and microbiologic methods. both methods equally frequently detected c. pylori (in 87 +/- 5 and in 85 +/- 6 percent of cases, respectively). c. pylori were more frequently detected during ulcer exacerbation than during remissions. detection of the agent in smears of smashed mucosal biopsy specimens was found to be a rapid diagnostic method, permitting detect ... | 1990 | 2374966 |
| prevalence of helicobacter (formerly campylobacter) pylori infection in saudia arabia, and comparison of those with and without upper gastrointestinal symptoms. | a causative role is now accepted for helicobacter (formerly campylobacter) pylori in type b gastritis, and evidence is accumulating that h. pylori infection plays a major contributory role in duodenal ulcer, gastric ulcer, and epidemic gastric cancer. the prevalence of h. pylori in any population remains unknown. we compared the prevalence of h. pylori infection in the riyadh region of saudia arabia, using a specific and sensitive elisa for igg antibody against the high molecular weight cell-ass ... | 1990 | 2375321 |
| non-steroidal anti-inflammatory drugs, hiatus hernia, and helicobacter pylori, in patients with oesophageal ulceration. | the frequency of oesophageal ulceration in 55 patients undergoing endoscopy for dyspeptic symptoms and who had recently used nsaids was studied, and compared with 86 patients seen in the same clinic who had not recently used these drugs. oesophageal ulceration was significantly more common in those who had used nsaids (p = 0.012), and also showed a highly significant association with the presence of a hiatus hernia (p less than 0.001). no association was found between the presence of gastric hel ... | 1990 | 2379044 |