Publications
| Title | Abstract | Year Filter | PMID(sorted ascending) Filter |
|---|
| eukaryotic association module in phage wo genomes from wolbachia. | viruses are trifurcated into eukaryotic, archaeal and bacterial categories. this domain-specific ecology underscores why eukaryotic viruses typically co-opt eukaryotic genes and bacteriophages commonly harbour bacterial genes. however, the presence of bacteriophages in obligate intracellular bacteria of eukaryotes may promote dna transfers between eukaryotes and bacteriophages. here we report a metagenomic analysis of purified bacteriophage wo particles of wolbachia and uncover a eukaryotic asso ... | 2016 | 27727237 |
| how did zika virus emerge in the pacific islands and latin america? | the unexpected emergence of zika virus (zikv) in the pacific islands and latin america and its association with congenital zika virus syndrome (czvs) (which includes microcephaly) and guillain-barré syndrome (gbs) have stimulated wide-ranging research. high densities of susceptible aedes spp., immunologically naive human populations, global population growth with increased urbanization, and escalation of global transportation of humans and commercial goods carrying vectors and zikv undoubtedly e ... | 2016 | 27729507 |
| chikungunya virus infection and diabetes mellitus: a double negative impact. | the impact of chikungunya virus (chikv) infection on diabetic patients (dps) has not been described. we aimed to compare clinical features of chikv infection in dps and nondiabetic patients (ndps), and to evaluate its effects on glycemic control among dps. we recorded clinical information and, in dps, glycemic control. forty-six dps and 53 ndps aged ≥ 20 years living in haiti, with acute chikv infection, were studied. diabetes duration was 7.1 ± 6.1 years. the most common acute chikv clinical ma ... | 2016 | 27729569 |
| zika: structuring the european research response. | studies are needed to assess #zika virus risks and to develop diagnostic tests http://ow.ly/zaozw. | 2016 | 27730165 |
| polyphenol-rich diets exacerbate ampk-mediated autophagy, decreasing proliferation of mosquito midgut microbiota, and extending vector lifespan. | mosquitoes feed on plant-derived fluids such as nectar and sap and are exposed to bioactive molecules found in this dietary source. however, the role of such molecules on mosquito vectorial capacity is unknown. weather has been recognized as a major determinant of the spread of dengue, and plants under abiotic stress increase their production of polyphenols. | 2016 | 27732590 |
| time-lagging interplay effect and excess risk of meteorological/mosquito parameters and petrochemical gas explosion on dengue incidence. | in kaohsiung, a metropolitan city in taiwan at high risk of dengue epidemic, weather factors combined with an accidental petrochemical gas explosion (pge) may affect mosquito‒human dynamics in 2014. generalized estimating equations with lagged-time poisson regression analyses were used to evaluate the effect of meteorological/mosquito parameters and pge on dengue incidences (2000-2014) in kaohsiung. increased minimum temperatures rendered a 2- and 3-month lagging interactive effect on higher den ... | 2016 | 27733774 |
| haemocoel injection of pira1b1 to galleria mellonella larvae leads to disruption of the haemocyte immune functions. | the bacterium photorhabdus luminescens produces a number of insecticidal proteins to kill its larval prey. in this study, we cloned the gene coding for a binary toxin pira1b1 and purified the recombinant protein using affinity chromatography combined with desalination technology. furthermore, the cytotoxicity of the recombinant protein against the haemocytes of galleria mellonella larvae was investigated. we found that the protein had haemocoel insecticidal activity against g. mellonella with an ... | 2016 | 27734915 |
| vector-borne disease, cities, and climate change. | 0 | 27737979 | |
| 0 | 27737980 | ||
| pyrethroid resistance in aedes aegypti and aedes albopictus: important mosquito vectors of human diseases. | aedes aegypti and a. albopictus mosquitoes are vectors of important human disease viruses, including dengue, yellow fever, chikungunya and zika. pyrethroid insecticides are widely used to control adult aedes mosquitoes, especially during disease outbreaks. herein, we review the status of pyrethroid resistance in a. aegypti and a. albopictus, mechanisms of resistance, fitness costs associated with resistance alleles and provide suggestions for future research. the widespread use of pyrethroids ha ... | 2016 | 27742355 |
| sex, mosquitoes and epidemics: an evaluation of zika disease dynamics. | since the first major outbreak reported on the island yap in 2007, the zika virus spread has alerted the scientific community worldwide. zika is an arbovirus transmitted by aedes mosquitoes; particularly in central and south america, the main vector is the same mosquito that transmits dengue and chikungunya, aedes aegypti. seeking to understand the dynamics of spread of the zika, in this paper, three mathematical models are presented, in which vector transmission of the virus, sexual contact tra ... | 2016 | 27743310 |
| dengue related osteonecrosis of the maxillary dento-alveolar bone. | dengue is a mosquito transmitted flaviviral infection which can give rise to severe haemorrhage (dengue haemorrhagic fever/dhf) and with capillary leakage induces hypovolemic shock (dengue shock syndrome/dss). although dengue symptoms and complications have been known for many decades there has only been one documented case of osteonecrosis of the maxilla which was treated by excision of the necrotic bone. in this case of dengue infection, extensive maxillary osteonecrosis and minimal root resor ... | 2016 | 27743399 |
| isolation and identification of mosquito (aedes aegypti) biting-deterrent compounds from the native american ethnobotanical remedy plant hierochloë odorata (sweetgrass). | hierochloë odorata (l.) p. beauv. (poaceae), commonly known as sweetgrass, has documented use as an insect repellent by the flatheads of montana and blackfoot of alberta. both the flatheads of montana and blackfoot of alberta would use braided plant material in a sachet in clothing or burn them from one end as incense, air/clothing freshener, and insect repellent. this study evaluated the insect-repellent properties of this plant using an in vitro mosquito aedes aegypti feeding bioassay-directed ... | 2016 | 27744691 |
| navigating the zika panic. | the epidemics of ebola virus in west africa and zika virus in america highlight how viruses can explosively emerge into new territories. these epidemics also exposed how unprepared we are to handle infectious disease emergencies. this is also true when we consider hypothesized new clinical features of infection, such as the associations between zika virus infection and severe neurological disease, including microcephaly and guillain-barré syndrome. on the surface, these pathologies appear to be ... | 2016 | 27746903 |
| changing clinical scenario in chandipura virus infection. | chandipura virus (chpv) (vesiculovirus: rhabdoviridae) garnered global attention as an emerging neurotropic pathogen inflicting high mortality in children within 24 h of commencement of symptoms. the 2003-2004 outbreaks in central india witnessed case fatality rates ranging from 56-75 per cent in andhra pradesh and gujarat with typical encephalitic symptoms. due to the acute sickness and rapid deterioration, the precise mechanism of action of the virus is still unknown. recent studies have shown ... | 0 | 27748295 |
| persistent zika virus detection in semen in a traveler returning to the united kingdom from brazil, 2016. | zika virus is normally transmitted by mosquitos, but cases of sexual transmission have been reported. we describe a patient with symptomatic zika virus infection in whom the virus was detected in semen for 92 days. our findings support recommendations for 6 months of barrier contraceptive use after symptomatic zika virus infection. | 2017 | 27748650 |
| morphological and transcriptomic analysis of a beetle chemosensory system reveals a gnathal olfactory center. | the red flour beetle tribolium castaneum is an emerging insect model organism representing the largest insect order, coleoptera, which encompasses several serious agricultural and forest pests. despite the ecological and economic importance of beetles, most insect olfaction studies have so far focused on dipteran, lepidopteran, or hymenopteran systems. | 2016 | 27751175 |
| risk of transmission of viral haemorrhagic fevers and the insecticide susceptibilitystatus of aedes aegypti (linnaeus) in some sites in accra, ghana. | dengue is one of the emerging diseases that can mostly only be controlled by vector control since there is no vaccine for the disease. although, dengue has not been reported in ghana, movement of people from neighbouring countries where the disease has been reported can facilitate transmission of the disease. | 0 | 27752187 |
| [translation into practice of empowerment strategies for dengue prevention: facilitators and barriers]. | objective to identify facilitators and barriers to the process of translating community empowerment strategies into the practice of the national aedes aegypti control program in cuba. methods a case study of the process was conducted from 2005 to 2009 at national and provincial levels of the control program. data from participant observation, in-depth interviews, and document analysis were triangulated and analyzed inductively and deductively. results the main facilitators identified included a ... | 2016 | 27754520 |
| vector-control response in a post-flood disaster setting, honiara, solomon islands, 2014. | the close quartering and exposed living conditions in evacuation centres and the potential increase in vector density after flooding in solomon islands resulted in an increased risk of exposure for the occupants to vectorborne diseases. | 2016 | 27757255 |
| mapping of courses on vector biology and vector-borne diseases systems: time for a worldwide effort. | major emergency efforts are being mounted for each vector-borne disease epidemiological crisis anew, while knowledge about the biology of arthropods vectors is dwindling slowly but continuously, as is the number of field entomologists. the discrepancy between the rates of production of knowledge and its use and need for solving crises is widening, in particular due to the highly differing time spans of the two concurrent processes. a worldwide web based search using multiple key words and search ... | 2016 | 27759770 |
| identification of aedes aegypti long intergenic non-coding rnas and their association with wolbachia and dengue virus infection. | long intergenic non-coding rnas (lincrnas) are appearing as an important class of regulatory rnas with a variety of biological functions. the aim of this study was to identify the lincrna profile in the dengue vector aedes aegypti and evaluate their potential role in host-pathogen interaction. the majority of previous rna-seq transcriptome studies in ae. aegypti have focused on the expression pattern of annotated protein coding genes under different biological conditions. here, we used 35 public ... | 2016 | 27760142 |
| open questions: how does wolbachia do what it does? | a common symbiont of insects, the bacterium wolbachia has been implicated in phenomena as diverse as sex determination, pathogen defence and speciation and is being used in public health programs to prevent mosquitoes transmitting disease. despite decades of research, we know remarkably little about how it exerts its effects. | 2016 | 27760540 |
| chikungunya virus transmission between aedes albopictus and laboratory mice. | chikungunya virus (chikv) is a mosquito-borne alphavirus associated with epidemics of acute and chronic arthritic disease in humans. aedes albopictus has emerged as an important new natural vector for chikv transmission; however, mouse models for studying transmission have not been developed. | 2016 | 27760560 |
| transcriptome response to elevated atmospheric co2 concentration in the formosan subterranean termite, coptotermes formosanus shiraki (isoptera: rhinotermitidae). | carbon dioxide (co2) is a pervasive chemical stimulus that plays a critical role in insect life, eliciting behavioral and physiological responses across different species. high co2 concentration is a major feature of termite nests, which may be used as a cue for locating their nests. termites also survive under an elevated co2 concentration. however, the mechanism by which elevated co2 concentration influences gene expression in termites is poorly understood. | 2016 | 27761326 |
| identification and temporal expression of putative circadian clock transcripts in the amphipod crustacean talitrus saltator. | talitrus saltator is an amphipod crustacean that inhabits the supralittoral zone on sandy beaches in the northeast atlantic and mediterranean. t. saltator exhibits endogenous locomotor activity rhythms and time-compensated sun and moon orientation, both of which necessitate at least one chronometric mechanism. whilst their behaviour is well studied, currently there are no descriptions of the underlying molecular components of a biological clock in this animal, and very few in other crustacean sp ... | 2016 | 27761341 |
| comparative profiling of micrornas in the winged and wingless english grain aphid, sitobion avenae (f.) (homoptera: aphididae). | micrornas (mirnas) are short single-stranded non-coding rnas that regulate gene expression, particularly during development. in this study, 345 mirnas were identified from the english green aphid, sitobion avenae (f.), of which 168 were conserved and 177 were s. avenae-specific. quantitative comparison of mirna expression levels indicated that 16 and 12 mirnas were significantly up-regulated in winged and wingless s. avenae small rna libraries, respectively. differential expression of these mirn ... | 2016 | 27762301 |
| juvenile hormone regulation of female reproduction in the common bed bug, cimex lectularius. | to begin studies on reproduction in common bed bug, cimex lectularius, we identified three genes coding for vitellogenin (vg, a protein required for the reproductive success of insects) and studied their hormonal regulation. rna interference studied showed that expression of vg3 gene in the adult females is a prerequisite for successful completion of embryogenesis in the eggs laid by them. juvenile hormone (jh) receptor, methoprene-tolerant (met), steroid receptor coactivator (src) and gataa but ... | 2016 | 27762340 |
| the mysterious zika virus: adding to the tropical flavivirus mayhem. | until now, known as the demure cousin of dengue virus (denv) inhabiting africa, zika virus (zikv) has reinvented itself to cause explosive epidemics captivating the western hemisphere. the outbreak causing potential for zikv was realized when it made its way from africa to yap island micronesia in 2007, and in french polynesia in 2013. from there, it moved on to brazil in 2015. now zikv has infected people in more than 33 countries in central and south america and the caribbean. moreover the epi ... | 0 | 27763483 |
| cloning and expression of ecdysone receptor and retinoid x receptor from procambarus clarkii: induction by eyestalk ablation. | ecdysone receptor and retinoid x receptor are key regulators in molting. here, full length ecdysone receptor (pcecr) and retinoid x receptor (pcrxr) cdnas from procambarus clarkii were cloned. full length cdna of pcecr has 2500 bp, encoding 576 amino acid proteins, and full length cdna of pcrxr has 2593 bp, in which a 15 bp and a 204 bp insert/deletion splice variant regions in dna binding domain and hinge domain were identified. the two splice variant regions in pcrxr result four isoforms: pcrx ... | 2016 | 27763563 |
| use of household cluster investigations to identify factors associated with chikungunya virus infection and frequency of case reporting in puerto rico. | chikungunya virus (chikv) is transmitted by aedes species mosquitoes and is the cause of an acute febrile illness characterized by potentially debilitating arthralgia. after emerging in the caribbean in late 2013, the first locally-acquired case reported to public health authorities in puerto rico occurred in may 2014. during june-august 2014, household-based cluster investigations were conducted to identify factors associated with infection, development of disease, and case reporting. | 2016 | 27764085 |
| imported chikungunya virus strains, taiwan, 2006-2014. | we identified 78 imported chikungunya cases in taiwan during 2006-2014. sixty-six (84.6%) cases were initially suspected to be dengue, which indicates the necessity for laboratory diagnostics in differentiation between dengue and chikungunya. results also emphasize the need for active surveillance of febrile illness at points of entry. | 0 | 27767908 |
| near-infrared spectroscopy, a rapid method for predicting the age of male and female wild-type and wolbachia infected aedes aegypti. | estimating the age distribution of mosquito populations is crucial for assessing their capacity to transmit disease and for evaluating the efficacy of available vector control programs. this study reports on the capacity of the near-infrared spectroscopy (nirs) technique to rapidly predict the ages of the principal dengue and zika vector, aedes aegypti. the age of wild-type males and females, and males and females infected with wmel and wmelpop strains of wolbachia pipientis were characterized u ... | 2016 | 27768689 |
| combining attractants and larvicides in biodegradable matrices for sustainable mosquito vector control. | there is a global need for cost-effective and environmentally friendly tools for control of mosquitoes and mosquito-borne diseases. one potential way to achieve this is to combine already available tools to gain synergistic effects to reduce vector mosquito populations. another possible way to improve mosquito control is to extend the active period of a given control agent, enabling less frequent applications and consequently, more efficient and longer lasting vector population suppression. | 2016 | 27768698 |
| effects of a novel β-lapachone derivative on trypanosoma cruzi: parasite death involving apoptosis, autophagy and necrosis. | natural products comprise valuable sources for new antiparasitic drugs. here we tested the effects of a novel β-lapachone derivative on trypanosoma cruzi parasite survival and proliferation and used microscopy and cytometry techniques to approach the mechanism(s) underlying parasite death. the selectivity index determination indicate that the compound trypanocidal activity was over ten-fold more cytotoxic to epimastigotes than to macrophages or splenocytes. scanning electron microscopy analysis ... | 2016 | 27770751 |
| a review of the mosquito species (diptera: culicidae) of bangladesh. | diseases caused by mosquito-borne pathogens remain an important source of morbidity and mortality in bangladesh. to better control the vectors that transmit the agents of disease, and hence the diseases they cause, and to appreciate the diversity of the family culicidae, it is important to have an up-to-date list of the species present in the country. original records were collected from a literature review to compile a list of the species recorded in bangladesh. | 2016 | 27770829 |
| aedes (stegomyia) albopictus' dynamics influenced by spatiotemporal characteristics in a brazilian dengue-endemic risk city. | brazil reported the majority of the dengue cases in americas during the last two decades, where the occurrence of human dengue cases is exclusively attributed to the aedes (stegomyia) aegypti (linnaeus). nowadays, other recognized dengue virus (denv) vector in asian countries, aedes (stegomyia) albopictus (skuse), has been detected in more than half of the 5565 brazilian municipalities. therefore, the aim of the present study was to investigate the presence of, and determine the ae. albopictus' ... | 2016 | 27771419 |
| molecular expression of aquaporin mrnas in the northern house mosquito, culex pipiens. | aquaporins (aqps) are a family of membrane-bound proteins, originally described as water-channels, that broadly exist in prokaryotic and eukaryotic cells. however, some aqps can transport small molecules (e.g. urea, glycerol) along with or preferentially to water. previous work in the mosquitoes aedes aegypti and anopheles gambiae have characterized the molecular expression of one or more aqp genes and shown that they are involved in water homeostasis after blood feeding, tolerance to dehydratio ... | 2017 | 27773635 |
| transstadial transmission and long-term association of crimean-congo hemorrhagic fever virus in ticks shapes genome plasticity. | the trade-off hypothesis, the current paradigm of arbovirus evolution, proposes that cycling between vertebrate and invertebrate hosts presents significant constraints on genetic change of arboviruses. studying these constraints in mosquito-borne viruses has led to a new understanding of epizootics. the trade-off hypothesis is assumed to be applicable to tick-borne viruses too, although studies are lacking. tick-borne crimean-congo hemorrhagic fever virus (cchfv), a member of the family bunyavir ... | 2016 | 27775001 |
| looking backward, looking forward: the long, torturous struggle with mosquitoes. | the american anti-mosquito movement grew out of the discovery of the role of mosquitoes in transferring pathogens and public concern about pest and nuisance mosquitoes in the late 1800s. in the 20th century, organized mosquito control in the united states passed through three eras: mechanical, chemical, and integrated mosquito control. mosquito control in the 21st century faces the challenge of emerging pathogens, invasive mosquito species, and balancing concerns about the environment with effec ... | 2016 | 27775554 |
| viral metagenomics on blood-feeding arthropods as a tool for human disease surveillance. | surveillance and monitoring of viral pathogens circulating in humans and wildlife, together with the identification of emerging infectious diseases (eids), are critical for the prediction of future disease outbreaks and epidemics at an early stage. it is advisable to sample a broad range of vertebrates and invertebrates at different temporospatial levels on a regular basis to detect possible candidate viruses at their natural source. however, virus surveillance systems can be expensive, costly i ... | 2016 | 27775568 |
| rna interference in moths: mechanisms, applications, and progress. | the vast majority of lepidopterans, about 90%, are moths. some moths, particularly their caterpillars, are major agricultural and forestry pests in many parts of the world. however, some other members of moths, such as the silkworm bombyx mori, are famous for their economic value. fire et al. in 1998 initially found that exogenous double-stranded rna (dsrna) can silence the homolog endogenous mrna in organisms, which is called rna interference (rnai). soon after, the rnai technique proved to be ... | 2016 | 27775569 |
| epa-registered repellents for mosquitoes transmitting emerging viral disease. | in many parts of the united states, mosquitoes were previously nuisance pests. however, they now represent a potential threat in the spread of viral diseases. the aedes aegypti, aedes albopictus, and culex species mosquitoes are endemic to the united states and together may transmit a variety of viral diseases of growing concern, including west nile virus, chikungunya, dengue fever, and zika virus. the centers for disease control and prevention and the environmental protection agency (epa) recom ... | 2016 | 27779781 |
| dengue outbreak in mombasa city, kenya, 2013-2014: entomologic investigations. | dengue outbreaks were first reported in east africa in the late 1970s to early 1980s including the 1982 outbreak on the kenyan coast. in 2011, dengue outbreaks occurred in mandera in northern kenya and subsequently in mombasa city along the kenyan coast in 2013-2014. following laboratory confirmation of dengue fever cases, an entomologic investigation was conducted to establish the mosquito species, and densities, causing the outbreak. affected parts of the city were identified with the help of ... | 2016 | 27783626 |
| vector competence of american mosquitoes for three strains of zika virus. | in 2015, zika virus (zikv; flaviviridae; flavivirus) emerged in the americas, causing millions of infections in dozens of countries. the rapid spread of the virus and the association with disease outcomes such as guillain-barré syndrome and microcephaly make understanding transmission dynamics essential. currently, there are no reports of vector competence (vc) of american mosquitoes for zikv isolates from the americas. further, it is not clear whether zikv strains from other genetic lineages ca ... | 2016 | 27783679 |
| genetic characterization of spondweni and zika viruses and susceptibility of geographically distinct strains of aedes aegypti, aedes albopictus and culex quinquefasciatus (diptera: culicidae) to spondweni virus. | zika virus (zikv) has extended its known geographic distribution to the new world and is now responsible for severe clinical complications in a subset of patients. while substantial genetic and vector susceptibility data exist for zikv, less is known for the closest related flavivirus, spondweni virus (sponv). both zikv and sponv have been known to circulate in africa since the mid-1900s, but neither has been genetically characterized by gene and compared in parallel. furthermore, the susceptibi ... | 2016 | 27783682 |
| distribution of the members of the pipiens assemblage in the sympatric area from argentina: which is where and when? | given their medical and veterinary relevance, the members of the pipiens assemblage are a worldwide target of ecological research. the distribution of culex pipiens s.s. and cx. quinquefasciatus converge in buenos aires, argentina, where hybrids have been detected. each member of the assemblage exhibits a distinct eco-physiological behaviour that can affect its efficiency in pathogen transmission. our aim was to identify the environmental drivers for the spatio-temporal distribution of each memb ... | 2016 | 27783720 |
| looking for inhibitors of the dengue virus ns5 rna-dependent rna-polymerase using a molecular docking approach. | the dengue virus (denv) nonstructural protein 5 (ns5) contains both an n-terminal methyltransferase domain and a c-terminal rna-dependent rna polymerase domain. polymerase activity is responsible for viral rna synthesis by a de novo initiation mechanism and represents an attractive target for antiviral therapy. the incidence of denv has grown rapidly and it is now estimated that half of the human population is at risk of becoming infected with this virus. despite this, there are no effective dru ... | 2016 | 27784988 |
| cgdb: a database of circadian genes in eukaryotes. | we report a database of circadian genes in eukaryotes (cgdb, http://cgdb.biocuckoo.org), containing ∼73 000 circadian-related genes in 68 animals, 39 plants and 41 fungi. circadian rhythm is ∼24 h rhythm in behavioral and physiological processes that exists in almost all organisms on the earth. defects in the circadian system are highly associated with a number of diseases such as cancers. although several databases have been established for rhythmically expressed genes, a comprehensive database ... | 2016 | 27789706 |
| expanding the knowledge on lignocellulolytic and redox enzymes of worker and soldier castes from the lower termite coptotermes gestroi. | termites are considered one of the most efficient decomposers of lignocelluloses on earth due to their ability to produce, along with its microbial symbionts, a repertoire of carbohydrate-active enzymes (cazymes). recently, a set of pro-oxidant, antioxidant, and detoxification enzymes (pad) were also correlated with the metabolism of carbohydrates and lignin in termites. the lower termite coptotermes gestroi is considered the main urban pest in brazil, causing damage to wood constructions. recen ... | 2016 | 27790186 |
| unsuspected dengue as a cause of acute febrile illness in children and adults in western nicaragua. | dengue is an emerging infectious disease of global significance. suspected dengue, especially in children in nicaragua's heavily-urbanized capital of managua, has been well documented, but unsuspected dengue among children and adults with undifferentitated fever has not. | 2016 | 27792777 |
| identification and analysis of a processed cytochrome p450 pseudogene of the disease vector aedes aegypti. | to clone cytochrome p450 from aedes aegypti (ae. aegypti) and determine the characteristics using bioinformatics tools. | 2016 | 27794391 |
| melaleuca quinquenervia (cav.) s.t. blake (myrtales: myrtaceae): natural alternative for mosquito control. | to evaluate an essential oil with larvicide, adulticide and growth inhibitory activity against aedes aegypti, aedes albopictus and culex quinquefasciatus mosquitoes, of medical importance. | 2016 | 27794392 |
| development and characterization of recombinant virus generated from a new world zika virus infectious clone. | zika virus (zikv; family flaviviridae, genus flavivirus) is a rapidly expanding global pathogen that has been associated with severe clinical manifestations, including devastating neurological disease in infants. there are currently no molecular clones of a new world zikv available that lack significant attenuation, hindering progress toward understanding determinants of transmission and pathogenesis. here we report the development and characterization of a novel zikv reverse genetics system bas ... | 2017 | 27795432 |
| filarial infection influences mosquito behaviour and fecundity. | understanding vector-parasite interactions is increasingly important as we move towards the endpoint goals set by the global programme for the elimination of lymphatic filariasis (gpelf), as interaction dynamics may change with reduced transmission pressure. elimination models used to predict programmatic endpoints include parameters for vector-specific transmission dynamics, despite the fact that our knowledge of the host-seeking behaviour of filariasis infected mosquitoes is lacking. we observ ... | 2016 | 27796352 |
| secreted ns1 protects dengue virus from mannose-binding lectin-mediated neutralization. | flavivirus nonstructural protein 1 (ns1) is a unique secreted nonstructural glycoprotein. although it is absent from the flavivirus virion, intracellular and extracellular forms of ns1 have essential roles in viral replication and the pathogenesis of infection. the fate of ns1 in insect cells has been more controversial, with some reports suggesting it is exclusively cell associated. in this study, we confirm ns1 secretion from cells of insect origin and characterize its physical, biochemical, a ... | 2016 | 27798151 |
| light-driven processes control both rhodopsin maturation and recycling in mosquito photoreceptors. | many invertebrates carry out a daily cycle of shedding and rebuilding of the photoreceptor's photosensitive rhabdomeric membranes. the mosquito aedes aegypti shows a robust response, losing nearly all aaop1 rhodopsin from the rhabdomeric membranes during the shedding process at dawn. here, we made use of aaop1 antibodies capable of distinguishing newly synthesized, glycosylated rhodopsin from mature nonglycosylated rhodopsin to characterize the fate of aaop1 during the shedding and rebuilding pr ... | 2016 | 27798185 |
| how much does inbreeding reduce heterozygosity? empirical results from aedes aegypti. | deriving strains of mosquitoes with reduced genetic variation is useful, if not necessary, for many genetic studies. inbreeding is the standard way of achieving this. full-sib inbreeding the mosquito aedes aegypti for seven generations reduced heterozygosity to 72% of the initial heterozygosity in contrast to the expected 13%. this deviation from expectations is likely due to high frequencies of deleterious recessive alleles that, given the number of markers studied (27,674 single nucleotide pol ... | 2017 | 27799643 |
| fundus findings in dengue fever: a case report. | dengue fever is a flavivirus infection transmitted through infected mosquitoes, and is endemic in southeast asia, central and south america, the pacific, africa and the eastern mediterranean region. a 41-year-old male patient had visual impairment after travelling to thailand, which is one of the endemic areas. cotton wool spots were observed on fundus examination. fundus fluorescein angiography showed minimal vascular leakage from areas near the cotton wool spots and dot hemorrhages in the macu ... | 2015 | 27800237 |
| essential oils enhance the toxicity of permethrin against aedes aegypti and anopheles gambiae. | insecticide resistance and growing public concern over the safety and environmental impacts of some conventional insecticides have resulted in the need to discover alternative control tools. naturally occurring botanically-based compounds are of increased interest to aid in the management of mosquitoes. susceptible strains of aedes aegypti (linnaeus) (diptera: culicidae) and anopheles gambiae (meigen) (diptera: culicidae) were treated with permethrin, a common type-i synthetic pyrethroid, using ... | 2017 | 27800630 |
| alkaloids with activity against the zika virus vector aedes aegypti (l.)-crinsarnine and sarniensinol, two new crinine and mesembrine type alkaloids isolated from the south african plant nerine sarniensis. | two new amaryllidaceae alkaloids, belonging to the mesembrine- and crinine-types, named crinsarnine (1) and sarniensinol (2), were isolated from the dried bulbs of nerine sarniensis together with bowdensine (3), sarniensine (4), hippadine (5) and 1-o-acetyl-lycorine (6). crinsarnine (1) and sarniensinol (2) were characterized using spectroscopic and chiroptical methods as (1s,2s,4ar,10bs)-2,7-dimethoxy-1,2,3,4,4a,6-hexahydro-5,11b-ethano[1,3]dioxolo-[4,5-j]phenanthridin-1-yl acetate and (6-(3ar, ... | 2016 | 27801807 |
| morphological differentiation of the eggs of north american container-inhabiting aedes mosquitoes. | aedes aegypti , ae. albopictus, ae. japonicus japonicus, and ae. triseriatus eggs are described with the aid of color images and images from scanning electron microscopy. all eggs were broadly cigar shaped with ae. triseriatus and ae. j japonicus eggs being dull or matte black, while ae. albopictus and ae. aegypti eggs were shiny jet black. aedes triseriatus eggs were lighter in color and had a rougher appearance when compared to those of ae. j. japonicus. aedes albopictus and ae. aegypti eggs c ... | 2016 | 27802396 |
| testing of visual and chemical attractants in correlation with the development and field evaluation of an autodissemination station for the suppression of aedes aegypti and aedes albopictus in florida. | three exotic mosquito-borne pathogens-dengue, chikungunya, and zika viruses-transmitted by aedes albopictus and ae. aegypti have undergone dramatic global expansion in recent years. the control of vector populations and minimizing bites from these vectors are the primary methods of reducing risk of transmission of these viruses to humans. however, ae. albopictus and ae. aegypti are notoriously challenging to control through conventional chemical means, due primarily to difficulties in applying p ... | 2016 | 27802398 |
| evaluation of a noncontact, alternative mosquito repellent assay system. | a novel noncontact repellency assay system (ncras) was designed and evaluated as a possible alternative method for testing compounds that repel or inhibit mosquitoes from blood feeding. deet and aedes aegypti were used in a controlled laboratory setting. using 2 study designs, a highly significant difference were seen between deet-treated and untreated skin placed behind the protective screens, indicating that deet was detected and was acting as a deterrence to mosquito landing and probing behav ... | 2016 | 27802399 |
| comparative excito-repellency of three cambodian plant-derived extracts against two mosquito vector species, aedes aegypti and anopheles minimus. | a study of the behavioral responses of aedes aegypti and anopheles minimus to 3 cambodian plant extracts at 3 different concentrations (1%, 2.5%, and 5%) was performed using an excito-repellency test system. these 3 plants were strophanthus scandens, capparis micracantha, and dioscorea hispida, selected according to traditional healer's knowledge, bibliographic studies and market surveys. results showed that s. scandens leaves' hexane extract was the only one to exert repellency against ae. aegy ... | 2016 | 27802401 |
| operational aspects of the centers for disease control and prevention autocidal gravid ovitrap. | dengue viruses cause hundreds of millions of infections every year in tropical and subtropical countries. unfortunately, there is not a single universal vector control method capable of suppressing aedes aegypti (l.) populations. amongst novel control tools or approaches are various types of traps targeting gravid females or their eggs. here, we provide details of the operational use of the centers for disease control and prevention autocidal gravid ovitrap (cdc-ago trap) for the surveillance an ... | 2016 | 27802402 |
| controlling aedes aegypti in cryptic environments with manually carried ultra-low volume and mist blower pesticide applications. | because aedes aegypti , a vector of dengue, chikungunya, and zika viruses, exhibits resting and reproductive behaviors that present challenges to control them, pesticide application equipment available for vector control must be evaluated for their ability to control this species in a variety of cryptic environments. five types of pesticide sprayers, representing 3 spray technologies (1 mister, 2 ultra-low volume [ulv] cold foggers, and 2 ulv thermal foggers), were evaluated for their ability to ... | 2016 | 27802406 |
| collagen extract from marine finfish scales as a potential mosquito larvicide. | collagen is a peptide being utilized in medical, health care, nutrient and decorative industry. marine fish scales are one of the good sources of collagen, which is extracted using the advanced enzymatic digestion method. scales of sardinella longiceps (oil sardine) have a high proportion of collagen. this product is well absorbed with broad adaptive values that encourage the inclusion of nutriments. in this paper, we have performed the isolation and characterization of collagen from s. longicep ... | 2016 | 27804059 |
| turmeric powder and its derivatives from curcuma longa rhizomes: insecticidal effects on cabbage looper and the role of synergists. | curcuma longa has well-known insecticidal and repellent effects on insect pests, but its impact on trichoplusia ni is unknown. in this study, the compound ar-turmerone, extracted and purified from c. longa rhizomes, was identified, and its insecticidal effects, along with turmeric powder, curcuminoid pigments and crude essential oil were evaluated against this important agricultural pest. the role of natural (sesamol and piperonal) and synthetic [piperonyl butoxide (pbo)] synergists under labora ... | 2016 | 27804972 |
| the seminal fluid proteome of the polyandrous red junglefowl offers insights into the molecular basis of fertility, reproductive ageing and domestication. | seminal fluid proteins (sfps) are emerging as fundamental contributors to sexual selection given their role in post-mating reproductive events, particularly in polyandrous species where the ejaculates of different males compete for fertilisation. sfp identification however remains taxonomically limited and little is known about avian sfps, despite extensive work on sexual selection in birds. we characterize the sf proteome of the polyandrous red junglefowl, gallus gallus, the wild species that g ... | 2016 | 27804984 |
| comprehensive dna methylation analysis of the aedes aegypti genome. | aedes aegypti mosquitoes are important vectors of viral diseases. mosquito host factors play key roles in virus control and it has been suggested that dengue virus replication is regulated by dnmt2-mediated dna methylation. however, recent studies have shown that dnmt2 is a trna methyltransferase and that dnmt2-dependent methylomes lack defined dna methylation patterns, thus necessitating a systematic re-evaluation of the mosquito genome methylation status. we have now searched the ae. aegypti g ... | 2016 | 27805064 |
| the queenslandensis and the type form of the dengue fever mosquito (aedes aegypti l.) are genomically indistinguishable. | the mosquito aedes aegypti (l.) is a major vector of viral diseases like dengue fever, zika and chikungunya. aedes aegypti exhibits high morphological and behavioral variation, some of which is thought to be of epidemiological significance. globally distributed domestic ae. aegypti have often been grouped into (i) the very pale variety queenslandensis and (ii) the type form. because the two color forms co-occur across most of their range, there is interest in understanding how freely they interb ... | 2016 | 27806047 |
| cross-mating compatibility and competitiveness among aedes albopictus strains from distinct geographic origins - implications for future application of sit programs in the south west indian ocean islands. | the production of large numbers of males needed for a sustainable sterile insect technique (sit) control program requires significant developmental and operational costs. this may constitute a significant economic barrier to the installation of large scale rearing facilities in countries that are undergoing a transition from being largely dependent on insecticide use to be in a position to integrate the sit against aedes albopictus. alternative options available for those countries could be to r ... | 2016 | 27806056 |
| genome-wide analysis of differentially expressed microrna in bombyx mori infected with nucleopolyhedrosis virus. | bombyx mori nucleopolyhedrosis virus (bmnpv) is a major pathogen that threatens the growth and sustainability of the sericulture industry. since micrornas (mirnas) have been shown to play important roles in host-pathogen interactions, in this study we investigated the effects of bmnpv infection on silkworm micrornas expression profile. to achieve this, we constructed and deep-sequenced two small rna libraries generated from bmnpv infected and un-infected larvae. the results revealed that 38 silk ... | 2016 | 27806111 |
| recombinase polymerase amplification assay for rapid detection of lumpy skin disease virus. | lumpy skin disease virus (lsdv) is a capripoxvirus infecting cattle and buffalos. lumpy skin disease (lsd) leads to significant economic losses due to hide damage, reduction of milk production, mastitis, infertility and mortalities (10 %). early detection of the virus is crucial to start appropriate outbreak control measures. veterinarians rely on the presence of the characteristic clinical signs of lsd. laboratory diagnostics including virus isolation, sequencing and real-time polymerase chain ... | 2016 | 27806722 |
| perplexing metabolomes in fungal-insect trophic interactions: a terra incognita of mycobiocontrol mechanisms. | the trophic interactions of entomopathogenic fungi in different ecological niches viz., soil, plants, or insect themselves are effectively regulated by their maneuvered metabolomes and the plethora of metabotypes. in this article, we discuss a holistic framework of co-evolutionary metabolomes and metabotypes to model the interactions of biocontrol fungi especially with mycosed insects. conventionally, the studies involving fungal biocontrol mechanisms are reported in the context of much aggrandi ... | 2016 | 27807434 |
| genome investigations of vector competence in aedes aegypti to inform novel arbovirus disease control approaches. | dengue (denv), yellow fever, chikungunya, and zika virus transmission to humans by a mosquito host is confounded by both intrinsic and extrinsic variables. besides virulence factors of the individual arboviruses, likelihood of virus transmission is subject to variability in the genome of the primary mosquito vector, aedes aegypti. the "vectorial capacity" of a. aegypti varies depending upon its density, biting rate, and survival rate, as well as its intrinsic ability to acquire, host and transmi ... | 2016 | 27809220 |
| sodium channel mutations and pyrethroid resistance in aedes aegypti. | pyrethroid insecticides are widely used to control insect pests and human disease vectors. voltage-gated sodium channels are the primary targets of pyrethroid insecticides. mutations in the sodium channel have been shown to be responsible for pyrethroid resistance, known as knockdown resistance (kdr), in various insects including mosquitoes. in aedes aegypti mosquitoes, the principal urban vectors of dengue, zika, and yellow fever viruses, multiple single nucleotide polymorphisms in the sodium c ... | 2016 | 27809228 |
| transcriptomic data from panarthropods shed new light on the evolution of insulator binding proteins in insects : insect insulator proteins. | body plan development in multi-cellular organisms is largely determined by homeotic genes. expression of homeotic genes, in turn, is partially regulated by insulator binding proteins (ibps). while only a few enhancer blocking ibps have been identified in vertebrates, the common fruit fly drosophila melanogaster harbors at least twelve different enhancer blocking ibps. we screened recently compiled insect transcriptomes from the 1kite project and genomic and transcriptomic data from public databa ... | 2016 | 27809783 |
| low sensitivity of the tourniquet test for differential diagnosis of dengue: an analysis of 28,000 trials in patients. | the aim of this study was to evaluate the utility of the tourniquet test (tt) for dengue diagnosing. to our knowledge, no previous study with such a large sample, of this duration, with as many laboratory methods referenced, or relating the results of the tt to the 2009 who classification of severity has been conducted thus far. | 2016 | 27809813 |
| mosquito populations dynamics associated with climate variations. | mosquitoes are responsible for the transmission of numerous serious pathogens. members of the aedes and culex genera, which include many important vectors of mosquito-borne diseases, are highly invasive and adapted to man-made environments. they are spread around the world involuntarily by humans and are highly adapted to urbanized environments, where they are exposed to climate-related abundance drivers. we investigated culicidae fauna in two urban parks in the city of são paulo to analyze the ... | 2017 | 27810426 |
| in silico study on anti-chikungunya virus activity of hesperetin. | the re-emerging, aedes spp. transmitted chikungunya virus (chikv) has recently caused large outbreaks in a wide geographical distribution of the world including countries in europe and america. though fatalities associated with this self-remitting disease were rarely reported, quality of patients' lives have been severely diminished by polyarthralgia recurrence. neither effective antiviral treatment nor vaccines are available for chikv. our previous in vitro screening showed that hesperetin, a b ... | 2016 | 27812412 |
| pyriproxyfen and the microcephaly epidemic in brazil - an ecological approach to explore the hypothesis of their association. | the microcephaly epidemic in brazil generated intense debate regarding its causality, and one hypothesised cause of this epidemic, now recognised as congenital zika virus syndrome, was the treatment of drinking water tanks with pyriproxyfen to control aedes aegypti larvae. we present the results of a geographical analysis of the association between the prevalence of microcephaly confirmed by fenton growth charts and the type of larvicide used in the municipalities that were home to the mothers o ... | 2016 | 27812601 |
| one year after the zika virus outbreak in brazil: from hypotheses to evidence. | zika virusis an arbovirus of the flaviviridae family with two major strains, an asian and an african strain. the main vectors involved in the transmission of zika virus are the aedes aegypti and aedes albopictus mosquitoes. despite its identification, discovered in 1947 in the zika forest in uganda, only isolated and sporadic occurrences of human infection were reported within a largely asymptomatic proportion of individuals. the first reported outbreak occurred in 2007 in the yap island, which ... | 2016 | 27812646 |
| detection of dengue virus serotypes 1, 2 and 3 in selected regions of kenya: 2011-2014. | dengue fever, a mosquito-borne disease, is associated with illness of varying severity in countries in the tropics and sub tropics. dengue cases continue to be detected more frequently and its geographic range continues to expand. we report the largest documented laboratory confirmed circulation of dengue virus in parts of kenya since 1982. | 2016 | 27814732 |
| magnetic nanoparticles are highly toxic to chloroquine-resistant plasmodium falciparum, dengue virus (den-2), and their mosquito vectors. | a main challenge in parasitology is the development of reliable tools to prevent or treat mosquito-borne diseases. we investigated the toxicity of magnetic nanoparticles (mnp) produced by magnetospirillum gryphiswaldense (strain msr-1) on chloroquine-resistant (cq-r) and sensitive (cq-s) plasmodium falciparum, dengue virus (den-2), and two of their main vectors, anopheles stephensi and aedes aegypti, respectively. mnp were studied by fourier-transform infrared spectroscopy and transmission elect ... | 2017 | 27815736 |
| resistance to genetic insect control: modelling the effects of space. | genetic insect control, such as self-limiting ridl(2) (release of insects carrying a dominant lethal) technology, is a development of the sterile insect technique which is proposed to suppress wild populations of a number of major agricultural and public health insect pests. this is achieved by mass rearing and releasing male insects that are homozygous for a repressible dominant lethal genetic construct, which causes death in progeny when inherited. the released genetically engineered ('ge') in ... | 2016 | 27816677 |
| mosquito-transmitted viruses - the great brazilian challenge. | arboviruses pose a serious threat to public health worldwide, overloading the healthcare system and causing economic losses. these viruses form a very diverse group, and in brazil, arboviruses belonging to the families flaviviridae and togaviridae are predominant. unfortunately, the number of arboviruses increases in proportion with factors such as deforestation, poor sanitation, climate changes, and introduction of new viruses like chikungunya virus and zika virus. in brazil, dengue is endemic, ... | 2016 | 27818091 |
| the formulation of the essential oil of piper aduncum linnaeus (piperales: piperaceae) increases its efficacy as an insect repellent. | the essential oil (eo) of piper aduncum linnaeus, known as 'sireh lada' to locals malaysian, has the potential to be used as an alternative to synthetic insect repellents such as n,n-diethyl-meta-toluamide. however, the eo's efficacy as a repellent decreases after application due to the high volatility of its active ingredients. a number of studies have showed that optimizing the formulation of plant-based eos can improve their efficacy as repellents. the present study sought to evaluate the eff ... | 2017 | 27819201 |
| talen-mediated knock-in via non-homologous end joining in the crustacean daphnia magna. | transcription activator-like effector nucleases (talens) are versatile tools that enable the insertion of dna into different organisms. here, we confirmed talen-mediated knock-in via non-homologous end joining in the crustacean daphnia magna, a model organism for ecological and toxicological genomics. we tested two different talens, ey1 talen and ey2 talen, both of which target the eyeless locus. the donor dna plasmid, harbouring the h2b-gfp reporter gene, was designed to contain both talen targ ... | 2016 | 27819301 |
| an evaluation of educational interventions aimed at decreasing aedes aegypti mosquito breeding sites: a systematic review. | 2011 | 27820243 | |
| the epidemiological characteristics and dynamic transmission of dengue in china, 2013. | there was a dengue epidemic in several regions of china in 2013. no study has explored the dynamics of dengue transmission between different geographical locations with dengue outbreaks in china. the purpose of the study is to analyze the epidemiological characteristics and to explore the dynamic transmission of dengue in china, 2013. | 2016 | 27820815 |
| a cluster-randomized controlled trial to reduce diarrheal disease and dengue entomological risk factors in rural primary schools in colombia. | as many neglected tropical diseases are co-endemic and have common risk factors, integrated control can efficiently reduce disease burden and relieve resource-strained public health budgets. diarrheal diseases and dengue fever are major global health problems sharing common risk factors in water storage containers. where provision of clean water is inadequate, water storage is crucial. fecal contamination of stored water is a common source of diarrheal illness, but stored water also provides bre ... | 2016 | 27820821 |
| transcriptome analysis of the midgut of the chinese oak silkworm antheraea pernyi infected with antheraea pernyi nucleopolyhedrovirus. | the antheraea pernyi nucleopolyhedrovirus (apnpv) is an exclusive pathogen of a. pernyi. the intense interactions between apnpv and a. pernyi cause a series of physiological and pathological changes to a. pernyi. however, no detailed report exists regarding the molecular mechanisms underlying the interactions between apnpv and a. pernyi. in this study, four cdna libraries of the a. pernyi midgut, including two apnpv-infected groups and two control groups, were constructed for transcriptomic anal ... | 2016 | 27820844 |
| the physical genome mapping of anopheles albimanus corrected scaffold misassemblies and identified interarm rearrangements in genus anopheles. | the genome of the neotropical malaria vector anopheles albimanus was sequenced as part of the 16 anopheles genomes project published in 2015. the draft assembly of this species consisted of 204 scaffolds with an n50 scaffold size of 18.1 mb and a total assembly size of 170.5 mb. it was among the smallest genomes with the longest scaffolds in the 16 anopheles species cluster, making an. albimanus the logical choice for anchoring the genome assembly to chromosomes. in this study, we developed a hi ... | 2017 | 27821634 |
| how social structures, space, and behaviors shape the spread of infectious diseases using chikungunya as a case study. | whether an individual becomes infected in an infectious disease outbreak depends on many interconnected risk factors, which may relate to characteristics of the individual (e.g., age, sex), his or her close relatives (e.g., household members), or the wider community. studies monitoring individuals in households or schools have helped elucidate the determinants of transmission in small social structures due to advances in statistical modeling; but such an approach has so far largely failed to con ... | 2016 | 27821727 |
| measuring haitian children's exposure to chikungunya, dengue and malaria. | to differentiate exposure to the newly introduced chikungunya virus from exposure to endemic dengue virus and other pathogens in haiti. | 2016 | 27821884 |
| microcephaly in north-east brazil: a retrospective study on neonates born between 2012 and 2015. | to assess the number of children born with microcephaly in the state of paraíba, north-east brazil. | 0 | 27821886 |
| afrocolombian ethnicity, a paradoxical protective factor against dengue. | dengue is a priority public health problem. during epidemics in cuba and haiti, ethnic african descendant population had lower risk of dengue, and the ethnic factor was proposed as a protective one. | 2016 | 27821892 |
| rapid detection strategies for the global threat of zika virus: current state, new hypotheses, and limitations. | the current scenario regarding the widespread zika virus (zikv) has resulted in numerous diagnostic studies, specifically in south america and in locations where there is frequent entry of travelers returning from zikv-affected areas, including pregnant women with or without clinical symptoms of zikv infection. the world health organization, who, announced that millions of cases of zikv are likely to occur in the usa in the near future. this situation has created an alarming public health emerge ... | 2016 | 27822207 |