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molecular detection of bartonella spp. in deer ked (lipoptena cervi) in poland.the bacteria of the genus bartonella are obligate parasites of vertebrates. their distribution range covers almost the entire world from america, europe, asia to africa and australia. some species of bartonella are pathogenic for humans. their main vectors are blood-sucking arthropods such as fleas, ticks and blood-feeding flies. one such dipteran able to transfer vector-borne pathogens is the deer ked (lipoptena cervi) of the family hippoboscidae. this species acts as a transmitter of bartonell ...201729037227
endemic chronic wasting disease causes mule deer population decline in wyoming.chronic wasting disease (cwd) is a fatal transmissible spongiform encephalopathy affecting white-tailed deer (odocoileus virginianus), mule deer (odocoileus hemionus), rocky mountain elk (cervus elaphus nelsoni), and moose (alces alces shirasi) in north america. in southeastern wyoming average annual cwd prevalence in mule deer exceeds 20% and appears to contribute to regional population declines. we determined the effect of cwd on mule deer demography using age-specific, female-only, cwd transi ...201729049389
gastrointestinal parasitic infections in dead or debilitated moose ( alces alces) in sweden.:  our objectives were to determine prevalence and intensity of gastrointestinal parasites of dead or euthanized emaciated moose in central and southern sweden ( n=50) and to assess parasite intensity as a major contributing factor in the poor condition of these moose. all animals were infected and most had gastrointestinal nematodes. seven parasite species were found in the abomasa and 10 species were found in the small intestine. coinfections were commonly found in the abomasum ( ostertagia an ...201829053430
evidence for decreasing sperm count in african population from 1965 to 2015.this meta-analysis, following our previous reports those documented an overall 57% diminution in mean sperm concentration around the globe over past 35 years and 32.5% decline in past 50 years in european population, attempts to report the declining trend of sperm concentrations in african population between 1965 and 2015.201729062337
updating the "risk index": a systematic review and meta-analysis of occupational injuries and work schedule characteristics.fatigue is a major risk factor for occupational 'accidents' and injuries, and involves dimensions of physical, mental, and muscular fatigue. these dimensions are largely influenced by temporal aspects of work schedules. the "risk index" combines four fatigue-related components of work schedules to estimate occupational 'accident' and injury risk based on empirical trends: shift type (morning, afternoon/evening, night), length and consecutive number, and on-shift rest breaks. since its first intr ...201729064297
association between chronic or acute use of antihypertensive class of medications and falls in older adults. a systematic review and meta-analysis.evaluating effect of acute or chronic use of antihypertensives on risk of falls in older adults.201829087440
ante-mortem detection of chronic wasting disease in recto-anal mucosa-associated lymphoid tissues from elk (cervus elaphus nelsoni) using real-time quaking-induced conversion (rt-quic) assay: a blinded collaborative study.prion diseases are transmissible spongiform encephalopathies (tses) characterized by fatal, progressive neurologic diseases with prolonged incubation periods and an accumulation of infectious misfolded prion proteins. antemortem diagnosis is often difficult due to a long asymptomatic incubation period, differences in the pathogenesis of different prions, and the presence of very low levels of infectious prion in easily accessible samples. chronic wasting disease (cwd) is a tse affecting both wil ...201729098931
low and high thermal tolerance characteristics for unfed larvae of the winter tick dermacentor albipictus (acari: ixodidae) with special reference to moose.we report that larvae of the winter tick dermacentor albipictus, the only stage that will quest for a host, can tolerate short-term cold shock down to -25°c and short-term heat shock as high as 46°c. unlike a three host-tick, larvae of d. albipictus have no preconditioning response to low or high temperature exposure by rapid cold hardening (rch) or heat hardening, and poor ability to acclimate to low and high temperature extremes. thermal tolerance limits were not improved as the result of larv ...201829103951
karyotype relationships among selected deer species and cattle revealed by bovine fish probes.the cervidae family comprises more than fifty species divided into three subfamilies: capreolinae, cervinae and hydropotinae. a characteristic attribute for the species included in this family is the great karyotype diversity, with the chromosomal numbers ranging from 2n = 6 observed in female muntiacus muntjak vaginalis to 2n = 70 found in mazama gouazoubira as a result of numerous robertsonian and tandem fusions. this work reports chromosomal homologies between cattle (bos taurus, 2n = 60) and ...201729112970
the quality of australian indigenous primary health care research focusing on social and emotional wellbeing: a systematic review.objectives and importance of the study: primary health care research focused on aboriginal and torres strait islander (indigenous) people is needed to ensure that key frontline services provide evidence based and culturally appropriate care. we systematically reviewed the published primary health care literature to identify research designs, processes and outcomes, and assess the scientific quality of research focused on social and emotional wellbeing. this will inform future research to improve ...201729114717
spatio-temporal trends in crop damage inform recent climate-mediated expansion of a large boreal herbivore into an agro-ecosystem.large-scale climatic fluctuations have caused species range shifts. moose (alces alces) have expanded their range southward into agricultural areas previously not considered moose habitat. we found that moose expansion into agro-ecosystems is mediated by broad-scale climatic factors and access to high-quality forage (i.e., crops). we used crop damage records to quantify moose presence across the canadian prairies. we regressed latitude of crop damage against north atlantic oscillation (nao) and ...201729123188
occupational noise exposure and the risk for work-related injury: a systematic review and meta-analysis.occupational noise exposure has been linked to work-related injuries. strategies to control occupational hazards often rely on dose-response relationships needed to inform policy, but quantitative synthesis of the relevant literature has not been done so far. this study aimed to systematically review the epidemiological literature and to perform meta-analysis of the risk for work-related injury due to occupational noise exposure.201729136415
mapping the association between vitamin d and low back pain: a systematic review and meta-analysis of observational studies.low back pain (lbp) is the highest contributor to disability worldwide, with current intervention strategies only providing small to moderate analgesic effects. the use of vitamin d supplementation for lbp has gained interest due to its proposed anti-inflammatory and neuromodulatory properties. however, it is still unclear whether vitamin d levels differ between those with and without lbp or if vitamin d levels are associated with pain intensity.201729149142
cancer risk associated with nuclear atypia in cytologically indeterminate thyroid nodules: a systematic review and meta-analysis.indeterminate categories of thyroid cytopathology (categories b-iii and b-iv of the bethesda system) are integrated by a heterogeneous spectrum of cytological scenarios that are generally clustered for analysis and management recommendations. it has been suggested that aspirates exhibiting nuclear atypia have a higher risk of malignancy. this study aimed to assess whether cytologically indeterminate thyroid nodules with nuclear atypia have a significantly higher cancer risk than those without nu ...201729160163
a systematic review and meta-analysis of lifestyle and body mass index predictors of successful assisted reproductive technologies.lifestyle (smoking, drinking alcohol) and body mass index (bmi) predictors of successful outcomes in assisted reproductive technology (art) treatments were examined in this meta-analysis.201729172958
duration of untreated psychosis and neurocognitive functioning in first-episode psychosis: a systematic review and meta-analysis.previous reviews suggest there is minimal evidence for an association between duration of untreated psychosis (dup) and neurocognition. this is based on tallied findings of studies with small samples and neurocognition viewed as a single construct. we aimed to conduct a systematic review and meta-analysis examining the association between dup and individual neurocognitive domains and tests in first-episode psychosis (fep).201729173201
assessing health care access and use among indigenous peoples in alberta: a systematic review.alberta's indigenous population is growing, yet health care access may be limited. this paper presents a comprehensive review on health care access among indigenous populations in alberta with a focus on the health care services use and barriers to health care access. scientific databases (pubmed, embase, cinahl, and psycinfo) and online search engines were systematically searched for studies and grey literature published in english between 2000 and 2013 examining health care services access, us ...201729176095
fitness correlates of age at primiparity in a hunted moose population.trade-offs between fitness-related traits are predicted from the principle of resource allocation, where increased fecundity or parental investment leads to reduced future reproduction or survival. however, fitness traits can also be positively correlated due to individual differences (e.g. body mass). age at primiparity could potentially explain variation in individual fitness either because early primiparity is costly, or it may lead to higher lifetime reproductive success. based on long-term ...201729197974
brominated flame retardants and toxic elements in the meat and liver of red deer (cervus elaphus), wild boar (sus scrofa), and moose (alces alces) from latvian wildlife.in order to evaluate the contamination status of terrestrial biota in latvia, muscle and liver tissues of red deer (cervus elaphus), wild boar (sus scrofa), and moose (alces alces) were analyzed for the content of polybrominated diphenyl ethers (pbde), hexabromocyclododecane (hbcd), tetrabromobisphenol a (tbbpa), as well as cadmium and lead. the highest mean concentrations of pbdes (46.6pgg-1 wet weight (w.w.)), cadmium (0.95mgkg-1 w.w.), and lead (0.22mgkg-1 w.w.) were observed in the tissues o ...201729202283
climate warming is associated with smaller body size and shorter lifespans in moose near their southern range limit.despite the importance of body size for individual fitness, population dynamics and community dynamics, the influence of climate change on growth and body size is inadequately understood, particularly for long-lived vertebrates. although temporal trends in body size have been documented, it remains unclear whether these changes represent the adverse impact of climate change (environmental stress constraining phenotypes) or its mitigation (via phenotypic plasticity or evolution). concerns have al ...201729226555
the impact of human leukocyte antigen mismatching on graft survival and mortality in adult renal transplantation: a protocol for a systematic review and meta-analysis.human leukocyte antigen (hla) was important biological barrier to a successful transplantation. quantitative evaluations of the effect of hla mismatching on heart, liver, umbilical cord blood, and hematopoietic stem cell transplantation, have previously been reported. in new era of immunosuppression, the reported magnitude effect of hla mismatching on survival outcomes of kidney transplantation was controversial. in addition, the current kidney allocation guideline recommendations in different c ...201729245253
incidence of malignant hyperthermia in patients undergoing general anesthesia: protocol for a systematic review and meta-analysis.malignant hyperthermia (mh) continues to be of potential concern for clinicians whenever inhalational anesthetic agents or succinylcholine are used, because mh is a potentially fatal metabolic disorder.201729245345
protocolized laboratory screening for the medical clearance of psychiatric patients in the emergency department: a systematic review.emergency department (ed) patients with psychiatric chief complaints undergo medical screening to rule out underlying or comorbid medical illnesses prior to transfer to a psychiatric facility. this systematic review attempts to determine the clinical utility of protocolized laboratory screening for the streamlined medical clearance of ed psychiatric patients by determining the clinical significance of individual laboratory results.201729266617
yew (taxus) intoxication in free-ranging cervids.wild ruminants, including deer species (cervids) have incorrectly been regarded as refractory to yew (taxus) intoxication. this assumption has been based upon anecdotal observations of individual deer browsing on yew over time without apparent adverse effect. a single case of yew intoxication was reported in a free-ranging norwegian moose (alces alces) in 2008. the current report describes five additional cases of yew toxicosis in moose, seven in roe deer (capreolus capreolus) and two in reindee ...201729281648
prevalence of work-related musculoskeletal disorders among surgeons and interventionalists: a systematic review and meta-analysis.physicians in procedural specialties are at high risk for work-related musculoskeletal disorders (msds). this has been called "an impending epidemic" in the context of the looming workforce shortage; however, prevalence estimates vary by study.201729282463
laparoscopic vs open hepatectomy for hepatocellular carcinoma in patients with cirrhosis: a meta-analysis of the long-term survival outcomes.in patients with hepatocellular carcinoma (hcc) and cirrhosis, laparoscopic hepatectomy (lh) confers short-term benefits over open hepatectomy (oh) but the long-term outcomes of this procedure are unclear. this systematic review aims to compare the long-term survival outcomes of lh and oh for patients with hcc and underlying cirrhosis.201729284151
systematic review of nephrotoxicity of drugs of abuse, 2005-2016.the united states is faced with an unprecedented epidemic of drug abuse. every year thousands of americans visit the emergency departments all over the country with illicit drug related complaints. these drugs have been known to be associated with a range of renal pathologies, from reversible acute kidney injuries to debilitating irreversible conditions like renal infarction. so far, no comprehensive study or systematic review has been published that includes the commonly used street drugs and d ...201729287591
molecular taxonomy and subgeneric classification of tapeworms of the genus moniezia blanchard, 1891 (cestoda, anoplocephalidae) in northern cervids (alces and rangifer).phylogenetic relationships of tapeworms of the genus moniezia blanchard, 1891 (cestoda, anoplocephalidae) parasitizing the eurasian elk alces alces, the moose a. americanus and the reindeer/caribou rangifer tarandus (cervidae) were studied using dna sequences of two mitochondrial genes (cox1 and nad1). several isolates from domestic ruminants, representing moniezia expansa (rudolphi, 1810) sensu lato and m. benedeni (moniez, 1879) sensu lato, and one unidentified isolate from an african antelope ...201729288139
stable isotope signatures of large herbivore foraging habitats across europe.we investigated how do environmental and climatic factors, but also management, affect the carbon (δ13c) and nitrogen (δ15n) stable isotope composition in bone collagen of the two largest contemporary herbivores: european bison (bison bonasus) and moose (alces alces) across europe. we also analysed how different scenarios of population recovery- reintroduction in bison and natural recovery in moose influenced feeding habitats and diet of these two species and compared isotopic signatures of mode ...201829293647
comparative metagenomics of cellulose- and poplar hydrolysate-degrading microcosms from gut microflora of the canadian beaver (castor canadensis) and north american moose (alces americanus) after long-term enrichment.to identify carbohydrate-active enzymes (cazymes) that might be particularly relevant for wood fiber processing, we performed a comparative metagenomic analysis of digestive systems from canadian beaver (castor canadensis) and north american moose (alces americanus) following 3 years of enrichment on either microcrystalline cellulose or poplar hydrolysate. in total, 9,386 genes encoding cazymes and carbohydrate-binding modules (cbms) were identified, with up to half predicted to originate from f ...201729326667
barriers to peritoneal dialysis in aboriginal patients.aboriginal people in canada have an unduly high burden of end-stage kidney disease (eskd) and many live in rural settings. peritoneal dialysis (pd) is a home-based dialysis modality that may provide a valuable alternative to in-center hemodialysis which is relatively underutilized by the aboriginal population.201829326842
time series sightability modeling of animal populations.logistic regression models-or "sightability models"-fit to detection/non-detection data from marked individuals are often used to adjust for visibility bias in later detection-only surveys, with population abundance estimated using a modified horvitz-thompson (mht) estimator. more recently, a model-based alternative for analyzing combined detection/non-detection and detection-only data was developed. this approach seemed promising, since it resulted in similar estimates as the mht when applied t ...201829329309
what causes psychosis? an umbrella review of risk and protective factors.psychosis is a heterogeneous psychiatric condition for which a multitude of risk and protective factors have been suggested. this umbrella review aimed to classify the strength of evidence for the associations between each factor and psychotic disorders whilst controlling for several biases. the web of knowledge database was searched to identify systematic reviews and meta-analyses of observational studies which examined associations between socio-demographic, parental, perinatal, later factors ...201829352556
low cigarette consumption and risk of coronary heart disease and stroke: meta-analysis of 141 cohort studies in 55 study reports.to use the relation between cigarette consumption and cardiovascular disease to quantify the risk of coronary heart disease and stroke for light smoking (one to five cigarettes/day).201829367388
damage capitation in the modern liability climate: a primer for neurosurgeons and systematic review of the literature.objective neurosurgery, and particularly spine surgery, is among the most highly litigated medical specialties in the us, rendering the current malpractice climate of primary importance to spine surgeons nationwide. one of the primary methods of tort reform in the civil justice system is malpractice damage capitation (or "caps"); however, its efficacy is widely debated. the purpose of this article is to serve as a review for the practicing neurosurgeon, with particular emphasis on short- and lon ...201829372862
moose selecting for specific nutritional composition of birch places limits on food acceptability.despite decades of intense research, it remains largely unsolved which nutritional factors underpin food selection by large herbivores in the wild. we measured nutritional composition of birch foliage (betula pubescens) available to, and used by, moose (alces alces) in natural settings in two neighboring regions with contrasting animal body mass. this readily available food source is a staple food item in the diet of moose in the high-fitness region, but apparently underutilized by moose in the ...201829375784
influence of vitreomacular interface on anti-vascular endothelial growth factor treatment outcomes in neovascular age-related macular degeneration: a moose-compliant meta-analysis.the aim of the study was to evaluate the influence of vitreomacular interface configuration on treatment outcomes after intravitreal anti-vascular endothelial growth factor (anti-vegf) therapy for neovascular age-related macular degeneration (amd).the pubmed, embase, and cochrane central register of controlled trials databases were searched to identify relevant prospective or retrospective studies that evaluate the influence of vitreomacular adhesion (vma) or vitreomacular traction (vmt) on func ...201729390407
relationship between general anesthesia and alzheimer disease: a protocol for a systematic review and meta-analysis.alzheimer disease (ad) entails a long-term progressive decline in the cognitive ability to think and remember, and it has become a major concern for patients receiving surgery and anesthesia. however, studies investigating the relationship between general anesthesia and ad have yielded inconsistent results. therefore, we plan to perform a systematic review and meta-analysis to determine the relationship between general anesthesia and ad, and to verify whether general anesthesia is an independent ...201729390504
subtypes of benign breast disease as a risk factor for breast cancer: a systematic review and meta-analysis protocol.breast cancer is a multifactorial disease. benign breast disease (bbd) is one of the most important risk factors for breast cancer. the etiology of bbd is unknown. it is divided into nonproliferative and proliferative diseases. the selection of studies will be based on titles, abstract screening, inclusion and exclusion criteria, and quality assessment. previous studies have shown that all types of bbd increase the risk of breast cancer, but the risk degree is different for each one. accurate ri ...201829398746
meta-analysis of mortality in patients with high-risk intraductal papillary mucinous neoplasms under observation.although consensus guidelines suggest that patients with high-risk intraductal papillary mucinous neoplasms (ipmns) should have surgery, a non-operative strategy is often selected in patients who are poor surgical candidates. the aim was to determine the risk of disease-related death from ipmn in patients with worrisome features or high-risk stigmata who were kept under observation.201829405253
the structure of prpscprions.prpsc(scrapie isoform of the prion protein) prions are the infectious agent behind diseases such as creutzfeldt-jakob disease in humans, bovine spongiform encephalopathy in cattle, chronic wasting disease in cervids (deer, elk, moose, and reindeer), as well as goat and sheep scrapie. prpscis an alternatively folded variant of the cellular prion protein, prpc, which is a regular, gpi-anchored protein that is present on the cell surface of neurons and other cell types. while the structure of prpci ...201829414853
revascularization of radiation-induced carotid artery stenosis with carotid endarterectomy vs. carotid artery stenting: a systematic review and meta-analysis.the incidence of carotid artery stenosis after head and neck radiation is anticipated to rise due to the increasing survival of patients with head and neck malignancies. it remains unclear whether carotid artery stenting (cas) or endarterectomy (cea) is the best treatment strategy for radiation-induced carotid artery stenosis.201929422277
incidence, prevalence and clinical correlates of antidepressant-emergent mania in bipolar depression: a systematic review and meta-analysis.treatment-emergent mania (tem) represents a common phenomenon inconsistently reported across primary studies, warranting further assessment.201829441650
hepatitis b vaccination and the putative risk of central demyelinating diseases - a systematic review and meta-analysis.the anti-hepatitis b immunization campaigns launched in the early 1990s were a major public health breakthrough and targeted various populations (at-risk adults, newborns, adolescents). however, debate is still active about a possible link between this vaccine and central demyelination. this study provides a pooled estimate of this risk based on a comprehensive review and meta-analysis of all available epidemiologic studies.201829454521
cognitive outcomes of children born extremely or very preterm since the 1990s and associated risk factors: a meta-analysis and meta-regression.despite apparent progress in perinatal care, children born extremely or very preterm (ep/vp) remain at high risk for cognitive deficits. insight into factors contributing to cognitive outcome is key to improve outcomes after ep/vp birth.201829459939
prevalence and phylogenetic analysis of hepatitis e virus in pigs, wild boars, roe deer, red deer and moose in lithuania.hepatitis e virus (hev) is one of the major causes of acute viral hepatitis worldwide. in europe, food-borne zoonotic transmission of hev genotype 3 has been associated with domestic pigs and wild boar. controversial data are available on the circulation of the virus in animals that are used for human consumption, and to date, no gold standard has yet been defined for the diagnosis of hev-associated hepatitis. to investigate the current hev infection status in lithuanian pigs and wild ungulates, ...201829471843
a snp resource for studying north american moose.background: moose ( alces alces) colonized the north american continent from asia less than 15,000 years ago, and spread across the boreal forest regions of canada and the northern united states (us).  contemporary populations have low genetic diversity, due either to low number of individuals in the original migration (founder effect), and/or subsequent population bottlenecks in north america.  genetic tests based on informative single nucleotide polymorphism (snp) markers are helpful in forens ...201829479424
meta-analysis of risk of developing malignancy in congenital choledochal malformation.choledochal malformations comprise various congenital cystic dilatations of the extrahepatic and/or intrahepatic biliary tree. choledochal malformation is generally considered a premalignant condition, but reliable data on the risk of malignancy and optimal surgical treatment are lacking. the objective of this systematic review was to assess the prevalence of malignancy in patients with choledochal malformation and to differentiate between subtypes. in addition, the risk of malignancy following ...201829480528
disparities in the management of cardiovascular risk factors in patients with psychiatric disorders: a systematic review and meta-analysis.the high cardiovascular (cv) morbidity and mortality reported for patients with psychiatric disorders may possibly be due to a poorer management of cv risk factors (cvrfs). however, these healthcare disparities remain poorly understood. in this paper, studies comparing the management of smoking, diabetes, hypertension and dyslipidaemia, in patients with and without depression, anxiety, schizophrenia, bipolar or personality disorder, were reviewed.201829490716
proximal embolic protection versus distal filter protection versus combined protection in carotid artery stenting: a systematic review and meta-analysis.proximal embolic protection devices (p-epd) and distal filters (df) are used to prevent distal cerebral embolizations during carotid artery stenting (cas). we compared their comparative effectiveness in regards to prevention of intraprocedural and periprocedural adverse events, including ischemic lesions (ipsilateral and contralateral), stroke, transient ischemic attacks (tia) and death. we also compared the combination of the two neuroprotection strategies vs. a single strategy in regards to is ...201829502959
a technique for deployment of rumen bolus transmitters in free-ranging moose ( alces alces).recent uses for rumen boluses, such as mortality implant transmitters (mits), in wildlife have made it necessary to adapt deployment techniques developed for livestock. in 29 and 30 attempts to place mits in minnesota free-ranging moose ( alces alces) in 2013 and 2014, respectively, success was achieved 83% and 63% of the time. in 2014, new methods for mit deployment were evaluated in captive moose in alaska. mandible measurements provided guidance for selection of an appropriate-sized bolus app ...201829517432
gastrointestinal metastasis from primary lung cancer. case series and systematic literature review.aim of the present study is to report clinical characteristics and outcomes of patients treated in authors' hospital for gi metastasis from primary lung cancer, and to report and analyse the same data concerning patients retrieved from a systematic literature review. we performed a retrospective analysis of prospectively collected data, and a systematic review using the meta-analysis of observational studies in epidemiology (moose) guidelines. ninety-one patients were included, 5 patients from t ...201829567360
periodontal disease has an impact on patients' quality of life.data sourcesmedline, embase, opengrey, journal of clinical periodontology, journal of periodontology and a hand search of the bibliographies of retrieved publications.study selectiontwo reviewers screened the title and abstract of 1134 studies from the literature and selected 37 suitable publications for inclusion following full text analysis of 109 papers and agreement between both reviewers. the search included observational, epidemiological studies and clinical trials that fufilled the inclus ...201829568030
dash cam videos on youtube™ offer insights into factors related to moose-vehicle collisions.to gain a better understanding of the dynamics of moose-vehicle collisions, we analyzed 96 videos of moose-vehicle interactions recorded by vehicle dash-mounted cameras (dash cams) that had been posted to the video-sharing website youtube™. our objective was to determine the effects of road conditions, season and weather, moose behavior, and driver response to actual collisions compared to near misses when the collision was avoided. we identified 11 variables that were consistently observable in ...201829598877
accuracy of quick sequential organ failure assessment (qsofa) score and systemic inflammatory response syndrome (sirs) criteria for predicting mortality in hospitalized patients with suspected infection: a meta-analysis of observational studies.to identify sensitivity, specificity and predictive accuracy of quick sequential organ failure assessment (qsofa) score and systemic inflammatory response syndrome (sirs) criteria to predict in-hospital mortality in hospitalized patients with suspected infection.201829605565
stereotactic ablative radiation therapy versus surgery in early lung cancer: a meta-analysis of propensity score studies.as no completed randomized trials of surgery versus stereotactic ablative radiation therapy (sabr) in patients with early-stage non-small cell lung cancer are available, numerous propensity score studies have attempted to mimic the setting of clinical trials using nonrandomized data. we performed a meta-analysis of propensity score studies comparing sabr and surgery.201829619964
what have we learned in minimally invasive colorectal surgery from nsqip and nis large databases? a systematic review."big data" refers to large amount of dataset. those large databases are useful in many areas, including healthcare. the american college of surgeons national surgical quality improvement program (acs-nsqip) and the national inpatient sample (nis) are big databases that were developed in the usa in order to record surgical outcomes. the aim of the present systematic review is to evaluate the type and clinical impact of the information retrieved through nisqp and nis big database articles focused ...201829623415
mammal responses to the human footprint vary across species and stressors.a rapidly expanding human footprint - comprised of anthropogenic land-use change and infrastructure - is profoundly affecting wildlife distributions worldwide. cumulative effects management (cem) is a regional approach that seeks to manage combined effects of the human footprint on biodiversity across large spatial scales. challenges to implementing this approach include a lack of ecological data at large spatial scales, the high cost of monitoring multiple indicators, and the need to manage mul ...201829654972
human papillomavirus vaccine and demyelinating diseases-a systematic review and meta-analysis.approved in 2006, human papillomavirus (hpv) vaccines were initially targeted for girls aged 9-14 years. although the safety of these vaccines has been monitored through post-licensure surveillance programmes, cases of neurological events have been reported worldwide. the present study aimed to assess the risk of developing demyelination after hpv immunization by meta-analysing risk estimates from pharmacoepidemiologic studies. a systematic review was conducted in medline, embase, isi web of sci ...201829665426
lack of transmission of chronic wasting disease to cynomolgus macaques.chronic wasting disease (cwd) is a fatal prion disease that can infect deer, elk, and moose. cwd was first recognized in captive deer kept in wildlife facilities in colorado from 1967 to 1979. cwd has now been detected in 25 u.s. states, 2 canadian provinces, south korea, norway, and finland. it is currently unknown if humans are susceptible to cwd infection. understanding the health risk from consuming meat and/or products from cwd-infected cervids is a critical human health concern. previous r ...201829695429
prevalence and risk factors for musculoskeletal pain in keyboard musicians: a systematic review.to identify the prevalence and risk factors for musculoskeletal pain in keyboard musicians.201829705171
mineral licks as environmental reservoirs of chronic wasting disease prions.chronic wasting disease (cwd) is a fatal neurodegenerative disease of deer, elk, moose, and reindeer (cervids) caused by misfolded prion proteins. the disease has been reported across north america and recently discovered in northern europe. transmission of cwd in wild cervid populations can occur through environmental routes, but limited ability to detect prions in environmental samples has prevented the identification of potential transmission "hot spots". we establish widespread cwd prion con ...201829719000
an in vitro evaluation of browser and grazer fermentation efficiency and microbiota using european moose spring and summer foods.evolutionary morphological and physiological differences between browsers and grazers contribute to species-specific digestion efficiency of food resources. rumen microbial community structure of browsers is supposedly adapted to characteristic nutrient composition of the diet source. if this assumption is correct, domesticated ruminants, or grazers, are poor model animals for assessing the nutritional value of food consumed by browsing game species. in this study, typical spring and summer food ...201829721290
sika deer (cervus nippon)-specific real-time pcr method to detect fraudulent labelling of meat and meat products.since game meat is more valuable and expensive than meat from domesticated animal species it is a potential target for adulteration. analytical methods must allow the identification and quantification of meat species to be applicable for the detection of fraudulent labelling. we developed a real-time pcr assay for the authentication of sika deer (cervus nippon) and products thereof. the primer/probe system amplifies a 71 bp fragment of the kappa-casein precursor gene. since the target sequence c ...201829739996
incorporating road crossing data into vehicle collision risk models for moose (alces americanus) in massachusetts, usa.wildlife-vehicle collisions are a human safety issue and may negatively impact wildlife populations. most wildlife-vehicle collision studies predict high-risk road segments using only collision data. however, these data lack biologically relevant information such as wildlife population densities and successful road-crossing locations. we overcome this shortcoming with a new method that combines successful road crossings with vehicle collision data, to identify road segments that have both high b ...201829744581
brown bear (ursus arctos) attacks resulting in human casualties in scandinavia 1977-2016; management implications and recommendations.human persecution and habitat loss have endangered large carnivore populations worldwide, but some are recovering, exacerbating old conflicts. carnivores can injure and kill people; the most dramatic form of wildlife-human conflict. in scandinavia, the brown bear (ursus arctos) population increased from ~500 bears in 1977 to ~3300 in 2008, with an increase in injuries, fatalities, and public fear of bear attacks. we reviewed media coverage and interviewed victims to explore how bear population t ...201829791471
food in rural northern norway in relation to sami ethnicity: the saminor 2 clinical survey.to estimate current food intake in the population of northern norway and to investigate the impact of self-perceived sami ethnicity and region of residence on food intake.201829808789
discovery of snps for individual identification by reduced representation sequencing of moose (alces alces).monitoring of wild animal populations is challenging, yet reliable information about population processes is important for both management and conservation efforts. access to molecular markers, such as snps, enables population monitoring through genotyping of various dna sources. we have developed 96 high quality snp markers for individual identification of moose (alces alces), an economically and ecologically important top-herbivore in boreal regions. reduced representation libraries constructe ...201829847564
association of hypertensive disorders of pregnancy with risk of neurodevelopmental disorders in offspring: a systematic review and meta-analysis.although research suggests an association between hypertensive disorders of pregnancy (hdp) and autism spectrum disorder (asd), attention-deficit/hyperactivity disorder (adhd), and other neurodevelopmental disorders in offspring, consensus is lacking. given the increasing prevalence of hypertension in pregnancy, it is important to examine the association of hdp with neurodevelopmental outcome.201829874359
vitamin d and risk of preeclampsia: a systematic review and meta-analysis.human vitamin d levels have been increasingly related to a wide range of clinicaloutcomes. there is a large amount of reports on its associations, especially with obstetric complications,including preeclampsia and gestational diabetes. these results are scarcely consistent and there is stilla lack of quality intervention studies to confirm the role of vitamin d in those outcomes.objective: to review the available scientific evidence on the role of maternal vitamin d in the developmentof preeclam ...201829874709
civilian gunshot wounds to the head: prognostic factors affecting mortality: meta-analysis of 1774 patients.civilian gunshot wounds to the head (cgswh) are devastating, but there is no consensus regarding prognosis and management. therefore, we conducted a meta-analysis to identify prognostic factors associated with mortality. pubmed, embase, scopus, web of science, and cochrane library were queried for retrospective cohort studies of isolated cgswh reporting mortality prognostic factors. meta-analysis of observational studies in epidemiology (moose) guidelines were followed. study quality was assesse ...201829877141
identification of circular single-stranded dna viruses in faecal samples of canada lynx (lynx canadensis), moose (alces alces) and snowshoe hare (lepus americanus) inhabiting the colorado san juan mountains.the san juan mountains of southern colorado provide subalpine habitat for a suite of mammalian species including canada lynx (lynx canadensis), moose (alces alces) and snowshoe hare (lepus americanus). in the winter field season of 2016 five faecal samples from lynx, and one each from moose and snowshoe hare were collected to identify small single-stranded dna viruses associated with these three prominent species. thirty-two novel viruses were identified and classified as members of two well est ...201829879480
the association between phosphodiesterase type 5 inhibitor use and risk of non-arteritic anterior ischemic optic neuropathy: a systematic review and meta-analysis.phosphodiesterase type 5 inhibitors (pde5-is) are first-line drugs for erectile dysfunction. non-arteritic anterior ischemic optic neuropathy (naion) has been linked with pde5-i use. however, no meta-analysis or conclusive review has explored the association between naion and pde5-i use.201829884471
chronic wasting disease: an evolving prion disease of cervids.chronic wasting disease (cwd) is a relatively new and burgeoning prion epidemic of deer, elk, reindeer, and moose, which are members of the cervid family. while the disease was first described in captive deer, its subsequent discovery in various species of free-ranging animals makes it the only currently recognized prion disorder of both wild and farmed animals. in addition to its expanding range of host species, cwd continues to spread from north america to new geographic areas, including south ...201829887133
effective thiafentanil immobilization and physiological responses of free-ranging moose (alces alces) in northern sweden.to evaluate clinical and physiological responses in moose to thiafentanil administration for immobilization.201829891211
classical imaging in callosal agenesis.corpus callosal agenesis results in certain characteristic radiological appearances on magnetic resonance imaging. these classical named signs are revisited in this article.202029899788
magnitude and pattern of hypertension in the niger delta: a systematic review and meta-analysis of community-based studies.emerging evidence found that health inequality in the niger delta region in nigeria has continued to worsen due to epidemiological and environmental risks transitions. this study aims to provide an up-to-date review and the secular trends of hypertension prevalence in niger delta.201829899980
the conduct of australian indigenous primary health care research focusing on social and emotional wellbeing: a systematic review.objectives and importance of study: values and ethics: guidelines for ethical conduct in aboriginal and torres strait islander health research (values and ethics) describes key values that should underpin aboriginal and torres strait islander (indigenous)-focused health research. it is unclear how research teams address this document in primary health care research. we systematically review the primary health care literature focusing on indigenous social and emotional wellbeing (sewb) to identif ...201829925085
shorter ground contact time and better running economy: evidence from female kenyan runners.mooses, m, haile, dw, ojiambo, r, sang, m, mooses, k, lane, ar, and hackney, ac. shorter ground contact time and better running economy: evidence from female kenyan runners. j strength cond res xx(x): 000-000, 2018-previously, it has been concluded that the improvement in running economy (re) might be considered as a key to the continued improvement in performance when no further increase in v[combining dot above]o2max is observed. to date, re has been extensively studied among male east african ...201829952871
dose escalation in stereotactic body radiation therapy for pancreatic cancer: a meta-analysis.to determine whether increasing biologically effective dose (bed) with stereotactic body radiation therapy (sbrt) is associated with improved local control (lc) or toxicities in patients with locally advanced pancreatic cancer.201929965809
a framework to assess the quality of non-traditional articles in the field of disaster response and management.while carrying out a scoping review of earthquake response, we found that there is no universal standardized approach for assessing the quality of disaster evidence, much of which is variable or not peer reviewed. with the lack of a framework to ascertain the value and validity of this literature, there is a danger that valuable insights may be lost. we propose a theoretical framework that may, with further validation, address this gap.201929973300
cancer prevalence in pakistan: meta-analysis of various published studies to determine variation in cancer figures resulting from marked population heterogeneity in different parts of the country.pakistan's population is ethnically diverse with distinct ethnic groups inhabiting various parts of the country. cancer statistics obtained from specific regions populated by distinct ethnic groups may vary considerably. there is no national cancer registry. to determine whether there are indeed significant statistical differences in cancer incidence and prevalence, data was recorded from different parts of pakistan based on the ethnic composition of the population in those parts.201829976196
association between physical activity and risk of prevalent psoriasis: a moose-compliant meta-analysis.psoriasis is a common chronic relapsing immune-mediated inflammatory disease, whose prevalence has increased in recent years. some physicians believe that physical activity is associated with numerous health-related benefits in adults with dermatoses. while numerous studies have suggested an association between psoriasis and physical activity, others have yielded contradictory results. the aim of our study was to evaluate the association between the level of physical activity and prevalence of p ...201829979432
community strengths in addressing opioid use in northeastern ontario.the number of opioid-related deaths in ontario is rising, and remote first nations communities face unique challenges in providing treatment for opioid use disorder. geographic barriers and resource shortages limit access to opioid agonist therapy, such as buprenorphine or methadone. however, attempts to rapidly expand access have the potential to overlook community consultation. our experience in moose factory, ontario, offers insight into the ethical questions and challenges that can arise whe ...201829981036
microfilariae onchocerca alcis bain et rehbinder, 1986 – a new parasite of moose alces alces (l.) in polandonchocerca alcis bain et rehbinder, 1986 belongs to the subfamily onchocercinae. mature nematodes of o. alcis are located on the surface of hindlimb tendons. the aim of this article was to describe the occurrence of microfilariae of o. alcis in the skin of moose from kampinos forest. this is the first report of o. alcis in moose from poland and the third finding of this rare species in the world.201829983019
meta-analysis of the diagnostic and clinical utility of genome and exome sequencing and chromosomal microarray in children with suspected genetic diseases.genetic diseases are leading causes of childhood mortality. whole-genome sequencing (wgs) and whole-exome sequencing (wes) are relatively new methods for diagnosing genetic diseases, whereas chromosomal microarray (cma) is well established. here we compared the diagnostic utility (rate of causative, pathogenic, or likely pathogenic genotypes in known disease genes) and clinical utility (proportion in whom medical or surgical management was changed by diagnosis) of wgs, wes, and cma in children w ...201830002876
financial impact of patients enrolled in a medication adherence program at an independent community pharmacy.to determine the financial impact of attributed patients enrolled in a medication adherence program at community pharmacy enhanced services network (cpesn) pharmacies.201930006182
association between noise exposure and diabetes: a systematic review and meta-analysis.the prevalence of diabetes is on rise worldwide and environmental factors are being increasingly recognized to be involved in this rise. an emerging body of evidence has evaluated the impact of long-term exposure to noise on diabetes mellitus, highlighting the need to synthesize this evidence.201830006240
does primary lactase deficiency reduce bone mineral density in postmenopausal women? a systematic review and meta-analysis.postmenopausal osteoporosis is a significant cause of morbidity and mortality. the role of primary lactase deficiency (pld) in its development is not clear. this meta-analysis showed that pld is a risk factor for osteoporosis in postmenopausal women. these women need special attention in terms of screening for osteoporosis and its prevention.201830009335
the healthy weights initiative: results from the first 2,000 participants.a free, comprehensive, adult obesity reduction program was initiated in the cities of moose jaw and regina, saskatchewan, canada.201830013328
susceptibility of human prion protein to conversion by chronic wasting disease prions.chronic wasting disease (cwd) is a contagious and fatal neurodegenerative disease and a serious animal health issue for deer and elk in north america. the identification of the first cases of cwd among free-ranging reindeer and moose in europe brings back into focus the unresolved issue of whether cwd can be zoonotic like bovine spongiform encephalopathy. we used a cell-free seeded protein misfolding assay to determine whether cwd prions from elk, white-tailed deer, and reindeer in north america ...201830014840
violent criminal behavior in the context of bipolar disorder: systematic review and meta-analysis.despite the potential importance of understanding violent criminal behavior (vcb) in individuals suffering from bipolar disorder (bd), previous findings are conflicting. the aims of the present study are to clarify the association of vcb and bd in comparison to general population and other psychiatric conditions.201830014956
relative frequency and risk factors for long-term opioid therapy following surgery and trauma among adults: a systematic review protocol.when patients have been on opioid therapy for more than 90 days, more than half of them continue using opioids years later. knowing that long-term opioid consumption could lead to harmful side effects including misuse, abuse, and addiction, it is important to understand the risks of transitioning to prolonged opioid therapy to reduce its occurrence. perioperative and trauma contexts are ideal models commonly used to study such transition. long-term use of opioids might be associated with transfo ...201830021647
association of apathy with risk of incident dementia: a systematic review and meta-analysis.fear of dementia is pervasive in older people with cognitive concerns. much research is devoted to finding prognostic markers for dementia risk. studies suggest apathy in older people may be prodromal to dementia and could be a relevant, easily measurable predictor of increased dementia risk. however, evidence is fragmented and methods vary greatly between studies.201830027214
risk of colorectal cancer in patients with acute diverticulitis: a systematic review and meta-analysis of observational studies.we performed a systematic review and meta-analysis to assess the prevalence of colorectal cancer in patients with acute diverticulitis.201930056181
epidemiology and aetiologies of cryptococcal meningitis in africa, 1950-2017: protocol for a systematic review.cryptococcal meningitis is a neglected disease and an aids-defining illness, responsible for 15% of all aids-related deaths globally. in 2014, the estimated number of incident cryptococcal meningitis cases was 223 100, with 73% of them occurring in africa. currently available data on the prevalence, incidence, aetiologies and mortality of cryptococcal meningitis across africa are sparse and of limited quality. we propose to conduct the first systematic review to summarise the epidemiological dat ...201830061436
meta-analysis of gabrb3 gene polymorphisms and susceptibility to autism spectrum disorder.several lines of evidence have suggested that the gaba receptor subunit β3 (gabrb3) gene is a genetic contributor in the autism spectrum disorder (asd). the aberrant expression of gabrb3 is reported in asd patients which may be a consequence of the presence of certain genetic variants in the promoter region of the gene. the associations between single-nucleotide polymorphisms (snps) within this gene and asd have been analyzed in previous studies. however, the results are conflicting. in the pres ...201830074174
a novel technique for isolating dna from tempus™ blood rna tubes after rna isolation.we use tempus blood rna tubes (applied biosystems) during health assessments of american moose (alces alces spp.) as a minimally invasive means to obtain rna. here we describe a novel protocol to additionally isolate high-quality dna from the supernatant remaining after the rna isolation methodology. metrics used to qualify dna quality included measuring the concentration, obtaining a dna integrity number from a genomic dna screentape assay (agilent), and running the isolated dna on an agarose g ...201830081941
transuterine infection by baylisascaris transfuga: neurological migration and fatal debilitation in sibling moose calves (alces alces gigas) from alaska.larval baylisascaris nematodes (l3), resulting from transuterine infection and neural migration, were discovered in the cerebrum of sibling moose calves (alces alces gigas) near 1-3 days in age from alaska. we provide the first definitive identification, linking morphology, biogeography, and molecular phylogenetics, of baylisascaris transfuga in naturally infected ungulates. life history and involvement of paratenic hosts across a broader assemblage of mammals, from rodents to ungulates, in the ...201830094177
effect of cabergoline monotherapy in cushing's disease: an individual participant data meta-analysis.the primary treatment of choice for cushing's disease (cd) is the removal of the pituitary adenoma by transsphenoidal surgery (tss). the surgical failure is seen in up to 75% of cases depending on the experience of the surgeon in different studies. medical therapy is one of the options for the treatment of recurrent or persistent cd.201830097903
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