Publications
| Title | Abstract | Year Filter | PMID(sorted ascending) Filter |
|---|
| study on antimicrobial potential of neem oil nanoemulsion against pseudomonas aeruginosa infection in labeo rohita. | presence of several biochemical constituents in neem makes it an efficient antimicrobial agent for pathogenic diseases. the current investigation was aimed to assess the therapeutic potential of neem nanoemulsion as a control measure for pseudomonas aeruginosa infection in freshwater fish labeo rohita. the median lethal concentration (lc50) for the neem oil and neem nanoemulsion was 73.9 and 160.3 mg/l, respectively. the biomarker enzymes of treated fish tissues showed a significant difference i ... | 2016 | 24502533 |
| evaluation of acute toxicity of water extract of azadirachta indica leaves and seeds in rats. | this study 'in vivo' was applied on rats "rattus norvegicus" to determine the acute toxicity of water extracts of azadirachta indica leaves and seeds during 48 hours and the 50% lethal dose (ld50) values were calculated. different doses of a. indica water extracts of leaves and seeds were injected to the rats (rattus norvegicus) and the percentage of death was recorded during 48 hours. the present study, found that the percentage of death in all treated rats with a. indica leaves and seeds water ... | 2013 | 24505996 |
| inhibitory effect of azadirachta indica a. juss leaf extract on the activities of alpha-amylase and alpha-glucosidase. | in recent decades, there has been a drastic increase in the incidence and prevalence of diabetic mellitus. the aim of this study was to evaluate the in vitro inhibitory effect of azadirachita indica leaf extract on the activity of alpha-amylase and alpha-glucosidase as a means of alleviating hyperglycemia and managing diabetes mellitus. aqueous extract of azadirachita indica exhibited most potent alpha-amylase inhibitory activity with ic50 value of 9.15 mg ml(-1) and acetone extract exhibited mo ... | 2013 | 24511747 |
| azadirachta indica extract-artesunic acid combination produces an increased cure rate of plasmodium berghei-infected mice. | available artemisinin-combination therapies (acts) are expensive. various traditional herbal remedies for malaria involve plants, proven scientifically to have antiplasmodial effects, e.g., azadirachta indica a. juss. (meliaceae). | 2014 | 24517279 |
| neem oil poisoning as a cause of toxic encephalopathy in an infant. | 2014 | 24522945 | |
| in vitro antibacterial efficacy of 21 indian timber-yielding plants against multidrug-resistant bacteria causing urinary tract infection. | to screen methanolic leaf extracts of 21 timber-yielding plants for antibacterial activity against nine species of uropathogenic bacteria isolated from clinical samples of a hospital (enterococcus faecalis, staphylococcus aureus, acinetobacter baumannii, citrobacter freundii, enterobacter aerogenes, escherichia coli, klebsiella pneumoniae, proteus mirabilis, and pseudomonas aeruginosa). | 2013 | 24524024 |
| effects of neem oil (azadirachta indica a. juss) on the replacement of the midgut epithelium in the lacewing ceraeochrysa claveri during larval-pupal metamorphosis. | larvae of the lacewing ceraeochrysa claveri were fed on eggs of diatraeasaccharalis treated with neem oil at concentrations of 0.5%, 1% and 2% throughout the larval period. pupae obtained from treated larvae were used in the study at five days after the completion of cocoon spinning to investigate the effects of neem oil on the replacement of the midgut epithelium during the larval-pupal transition. we observed that the old larval epithelium was shed into the midgut lumen and transformed into th ... | 2014 | 24560939 |
| an ethnobotanical study of indigenous knowledge on medicinal plants used by the village peoples of thoppampatti, dindigul district, tamilnadu, india. | this study provides significant ethnopharmacological information, both qualitative and quantitative on medicinal plants in the thoppampatti village, dindigul district, tamilnadu, india. there is urgency in recording such data to conserve the traditional medicinal plants. this is the first ethnobotanical study which records the traditional important medicinal plants of thoppampatti village. to collect, analyze and evaluate the ethnopharmacologic knowledge in thoppampatti village in order to prote ... | 2014 | 24583241 |
| targeting stat3 phosphorylation by neem leaf glycoprotein prevents immune evasion exerted by supraglottic laryngeal tumor induced m2 macrophages. | tumor-associated macrophages (tams) are preferentially m2 skewed and promote tumor growth, angiogenesis, invasion, and/or metastasis. in this study, we have analyzed the in vitro immunomodulatory potential of a non-toxic neem leaf glycoprotein (nlgp) in reprogramming stage iii supraglottic laryngeal tumor cell lysate (sltcl) induced m2 tams to their classical anti-tumor shape (m1). data generated from this study support that nlgp is effective in preventing the sltcl induced generation (cd68(+)cd ... | 2014 | 24607970 |
| ethanolic neem (azadirachta indica) leaf extract prevents growth of mcf-7 and hela cells and potentiates the therapeutic index of cisplatin. | the present study was designed to gain insight into the antiproliferative activity of ethanolic neem leaves extract (enle) alone or in combination with cisplatin by cell viability assay on human breast (mcf-7) and cervical (hela) cancer cells. nuclear morphological examination and cell cycle analysis were performed to determine the mode of cell death. further, to identify its molecular targets, the expression of genes involved in apoptosis, cell cycle progression, and drug metabolism was analyze ... | 2014 | 24624140 |
| acaricidal effect of herbal extracts against cattle tick rhipicephalus (boophilus) microplus using in vitro studies. | the crude methanolic extract of datura stramonium, azadirachta indica, and calotropis procera leaves, allium sativum (as) cloves, and carica papaya (cp) seeds collected from banaskanta, gujarat (india) was tested for its acaricidal properties against rhipicephalus (boophilus) microplus. the percent adult mortality within 15 days, reproductive index, percentage inhibition of oviposition, hatching of laid ova, and percentage larval mortality were studied at concentrations of 12.5, 25, 50, and 100 ... | 2014 | 24633906 |
| cytotoxic and melanogenesis-inhibitory activities of limonoids from the leaves of azadirachta indica (neem). | seventeen limonoids (tetranortriterpenoids), 1-17, including three new compounds, i.e., 17-defurano-17-(2,5-dihydro-2-oxofuran-3-yl)-28-deoxonimbolide (14), 17-defurano-17-(2ξ-2,5-dihydro-2-hydroxy-5-oxofuran-3-yl)-28-deoxonimbolide (15), and 17-defurano-17-(5ξ-2,5-dihydro-5-hydroxy-2-oxofuran-3-yl)-2',3'-dehydrosalannol (17), were isolated from an etoh extract of the leaf of neem (azadirachta indica). the structures of the new compounds were elucidated on the basis of extensive spectroscopic an ... | 2014 | 24634075 |
| influence of formulation ratio of the plant components on the antimalarial properties of mama decoction. | mangifera indica, alstonia boonei, morinda lucida and azadirachta indica (mama) decoction, commonly prepared and used in nigeria from 1:1:1:1 ratio of mangifera indica l. (anacardiaceae), alstonia boonei de wild (apocynaceae), morinda lucida benth (rubiaceae), and azadirachta indica a. juss (meliaceae) leaves, plus four new variants of this combination were subjected to three in vivo antimalarial test models using chloroquine-sensitive plasmodium berghei berghei to determine the most active unde ... | 2014 | 24658658 |
| preclinical evaluation of the supercritical extract of azadirachta indica (neem) leaves in vitro and in vivo on inhibition of prostate cancer tumor growth. | azadirachta indica, commonly known as neem, has gained worldwide prominence because of its medical properties, namely antitumor, antiviral, anti-inflammatory, antihyperglycemic, antifungal, and antibacterial activities. despite these promising results, gaps remain in our understanding of the molecular mechanism of action of neem compounds and their potential for use in clinical trials. we investigated supercritical extract of neem leaves (senl) for the following: molecular targets in vitro, in v ... | 2014 | 24674886 |
| novel-porous-ag0 nanocomposite hydrogels via green process for advanced antibacterial applications. | silver nanoparticles (nps) antibacterial characteristics were depends on its particle stabilization, particles size and nucleation agent. in this study, we report on green process of porous silver nanocomposite hydrogels for advanced antibacterial applications. the porous poly(acrylamide) (pam) hydrogels were developed employing sucrose as porogenator. silver nps were nucleated with natural biomass neem (azadirachta indica) leaf extracts within the porous hydrogel networks. the formation of silv ... | 2014 | 24677385 |
| docking studies for screening anticancer compounds of azadirachta indica using saccharomyces cerevisiae as model system. | plants have a long history of use in the treatment of cancer. plant-derived compounds have played an important role in the development of several clinically useful anticancer agents. in the recent years, more emphasis has been placed on identifying plant-derived compounds that can be used as an effective treatment for life-threatening diseases such as cancer. cancer is a disease where there is abnormal cell proliferation. the proliferation of the cancer cells are restrained by cdk/cyclin complex ... | 2014 | 24678207 |
| dendrophthoe falcata (l.f) ettingsh (neem mistletoe): a potent bioresource to fabricate silver nanoparticles for anticancer effect against human breast cancer cells (mcf-7). | fabrication of metal nano scale particles through environmentally acceptable greener route has been focused with much interest in the present scenario. in this study aqueous leaf extract of mistletoe dendrophthoe falcata (l.f) ettingsh was successfully employed as a reducing and stabilizing agent to fabricate nanosilver particles (agnps) for biomedical applications. various reactions conditions such as temperature, ph, concentration of metal ion, incubation time and stoichiometric proportion of ... | 2014 | 24681313 |
| evaluating the antimicrobial activity of commercially available herbal toothpastes on microorganisms associated with diabetes mellitus. | the present study was conducted to evaluate the effcacy of commercially available herbal toothpastes against the different periodontopathogens. | 2013 | 24685799 |
| cyclonerol derivatives from trichoderma longibrachiatum ym311505. | a new sesquiterpene, 10,11-dihydrocyclonerotriol (1), together with two known compounds, catenioblin c (2) and sohirnone a (3), were isolated from trichoderma longibrachiatum ym311505, an endophytic fungus of azadirachta indica. their structures were characterized and identified by spectral analysis. compounds 1-3 exhibited antifungal activities against pyricularia oryzae and candida albicans. | 2014 | 24689203 |
| azadirachta indica modulates electrical properties and type of cell death in ndea-induced hepatic tumors. | tissue electrical conductivity is an important indicator of tissue structure and composition. present study demonstrates modulatory effect of azadirachta indica on the electrical conductivity and cell death in hepatic tumors. hepatic tumors were generated by intraperitoneal injection of n-nitrosodiethylamine (cumulative dose: 200 μg/g body mass) to male balb/c mice. aqueous a. indica leaf extract (aaile) was administered orally at a dosage of 100 μg/g body mass till the termination of experiment ... | 2014 | 24696076 |
| limonoids from azadirachta indica var. siamensis extracts and their cytotoxic and melanogenesis-inhibitory activities. | six new limonoids, 7-benzoyl-17-epinimbocinol (5), 3-acetyl-7-tigloylnimbidinin (8), 1-isovaleroyl-1-detigloylsalanninolide (15), 2,3-dihydro-3α-methoxynimbolide (16), deacetyl-20,21-epoxy-20,22-dihydro-21-deoxyisonimbinolide (26), and deacetyl-20,21,22,23-tetrahydro-20,22-dihydroxy-21,23-dimethoxynimbin (27), along with 28 known limonoids, 1-4, 6, 7, 9-14, 17-25, and 28-34, and two known flavonoids, 35 and 36, have been isolated from the extracts of bark, leaves, roots, and seeds of azadirachta ... | 2014 | 24706622 |
| hepatoprotective activity of the neem-based constituent azadirachtin-a in carbon tetrachloride intoxicated wistar rats. | the aim of this study was to investigate the hepatoprotective role of azadirachtin-a in carbon tetrachloride (ccl4) induced hepatotoxicity in rats. the group allotment for the animals used in the hepatoprotective study included a vehicle treatment group, ccl4 (1 ml · (kg body mass)(-1)) treatment group, silymarin (100 μg · (kg body mass)(-1) · day(-1)) + ccl4 treatment group, and groups treated with different doses of azadirachtin-a (100 or 200 μg · (kg body mass)(-1) · day(-1)) + ccl4. on the 9 ... | 2014 | 24708208 |
| ethnobotanical and antimicrobial study of some selected medicinal plants used in khyber pakhtunkhwa (kpk) as a potential source to cure infectious diseases. | present investigation deals with antimicrobial screening of ten medicinally important plants used by the inhabitants of district haripur, khyber pakhtunkhwa (kpk) for different infectious diseases. | 2014 | 24708514 |
| a rare case of toxic optic neuropathy secondary to consumption of neem oil. | a 35-year-old female was referred to our hospital with bilateral loss of vision of two days duration. she gave history of consumption of about 150 ml of neem oil five days back.examination revealed no perception of light in both eyes. both pupils were dilated and sluggishly reacting to light. her fundus examination showed bilateral hyperemic, edematous discs and also edema extending along the superior and inferior temporal vascular arcade. magnetic resonance imaging (mri) scan showed bilateral p ... | 2014 | 24722271 |
| a comparative study on the decomposition of edible and non-edible oil cakes in the gangetic alluvial soil of west bengal. | an experiment has been conducted under laboratory conditions to investigate the effect of decomposition of two edible oil cakes, viz. mustard cake (brassica juncea l) and groundnut cake (arachis hypogaea l), and two non-edible oil cakes, viz. mahua cake (madhuca indica gmel) and neem cake (azadirachta indica juss), at the rate of 5.0 t ha(-1) on the changes of microbial growth and activities in relation to transformations and availability of some plant nutrients in the gangetic alluvial (typic h ... | 2014 | 24733437 |
| transmission blocking activity of azadirachta indica and guiera senegalensis extracts on the sporogonic development of plasmodium falciparum field isolates in anopheles coluzzii mosquitoes. | targeting the stages of the malaria parasites responsible for transmission from the human host to the mosquito vector is a key pharmacological strategy for malaria control. research efforts to identify compounds that are active against these stages have significantly increased in recent years. however, at present, only two drugs are available, namely primaquine and artesunate, which reportedly act on late stage gametocytes. | 2014 | 24735564 |
| chemopreventive and therapeutic effects of nimbolide in cancer: the underlying mechanisms. | cancer chemoprevention is a strategy taken to block, reverse or retard the multistep process of carcinogenesis, including the blockage of its vital morphogenetic milestones viz. normal-preneoplasia-neoplasia-metastasis. naturally occurring phytochemicals are becoming increasingly popular over synthetic drugs for several reasons, including safety, efficacy and easy availability. nimbolide, a triterpene derived from the leaves and flowers of neem, is widely used in traditional medical practices fo ... | 2014 | 24759803 |
| in-vitro immunomodulatory and anti-cancerous activities of biotransformed products of dianabol through azadirachta indica and its molecular docking studies. | plant biotransformation is one of the tools for structural modifications of the organic substrate of low, moderate or high biological value utilizing plant cultured cells, these modifications of organic structures may lead to biologically augmented products and which may be ultimately substantial in cure or improvement of various morbidities and diseases. | 2013 | 24764465 |
| in vitro evaluation of antimicrobial effect of miswak against common oral pathogens. | miswak is a natural tooth cleaning tool which is being used in many parts of the world since ancient times. it is known to be useful in prevention of dental caries. but still it is not used as frequently as other oral hygiene tools. this research was designed to scientifically establish antimicrobial effect of miswak in vitro against common oral pathogens. | 2014 | 24772151 |
| sustainable management tactics for control of phyllotreta cruciferae (coleoptera: chrysomelidae) on canola in montana. | the crucifer flea beetle, phyllotreta cruciferae (goeze) (coleoptera: chrysomelidae), has recently emerged as a serious pest of canola (brassica napus l.) in montana. the adult beetles feed on canola leaves, causing many small holes that stunt growth and reduce yield. in 2013, damage to canola seedlings was high (approximately 80%) in many parts of montana, evidence that when flea beetles emerge in large numbers, they can quickly destroy a young canola crop. in the current study, the effectivene ... | 2014 | 24772547 |
| protective effect of azadirachta indica a. juss against doxorubicin-induced cardiac toxicity in tumour bearing mice. | doxorubicin (dox) treatment (12 microg/g body weight, once a week for 2 weeks) resulted in a significant decrease in the heart rate along with an increase in qrs, st, and qt intervals. histopathological studies showed cardiomyocyte degeneration, cytoplasmic vacuolation and macrophage infiltration in cardiac tissue. a marked increase in the rate of apoptosis was also observed. an increased oxidative stress was evidenced by significantly higher levels of lipid peroxidation (lpo) and depletion of r ... | 2014 | 24772935 |
| comparative anti-microbial efficacy of azadirachta indica irrigant with standard endodontic irrigants: a preliminary study. | the anti-microbial efficacy of 2.5% sodium hypochlorite (shc) and 0.2% chlorhexidine gluconate were compared with an experimental irrigant formulated from the neem tree, azadirachta indica a. juss. | 2014 | 24778508 |
| material and tableting properties of azadirachta indica gum with reference to official acacia gum. | this study determined the material and tableting properties of azadirachta indica gum (nmg) relative to acacia gum (aca). the morphological properties were assessed with size and shape factors of aspect ratio, roundness, irregularity and equivalent-circle-diameter. the tableting properties of the gums were determined using compressional characteristics, tensile strength (ts), brittle fracture index (bfi) and crushing-strength-friability/disintegration-time ratio (csfr/dt). the results suggest th ... | 2014 | 24779199 |
| azadirachta indica mitigates dmba-induced hepatotoxicity: a biochemical and radiometric study. | the hepatoprotective potential of aqueous azadirachta indica leaf extract (aaile) was assessed against dmba-induced hepatotoxicity. dmba (7,12-dimethylbenz[a] anthracene) treatment (40 mg/kg body weight, ip) to male balb/c mice resulted in the derailment of liver function as revealed by extremely slow clearance of 99mtc-mebrofenin from liver, elevated levels of alkaline phosphatase (alp) and alanine transaminase (alt), compared to control group. in addition, elevated micronuclei score and high a ... | 2014 | 24791415 |
| thrombolytic potential of ocimum sanctum l., curcuma longa l., azadirachta indica l. and anacardium occidentale l. | atherothrombotic diseases such as myocardial or cerebral infarction are serious consequences of the thrombus formed xin blood vessels. thrombolytic agents are used to dissolve the already formed clots in the blood vessels; however, these drugs have certain limitations which cause serious and sometimes fatal consequences. herbal preparations have been used since ancient times for the treatment of several diseases. the aim of this study was to investigate whether herbal preparations possess thromb ... | 2011 | 24826011 |
| iron-chelating, free radical scavenging and anti-proliferative activities of azadirachta indica. | excessive production of reactive oxygen species leads to oxidative stress which occurs in various diseases, such as diabetes, cancer, neurodegenerative diseases, and secondary iron overload in thalassemia. antioxidants are compounds that inhibit the oxidative processes and delay or suppress oxidative stress. phytochemicals in herbs are interesting sources of natural antioxidants with cancer preventive properties. the use of natural products is beneficial for the prevention and/or treatment of ox ... | 2014 | 24851563 |
| a plant-derived wound therapeutic for cost-effective treatment of post-surgical scalp wounds with exposed bone. | to evaluate efficacy and cost-effectiveness of a plant-derived wound dressing (one), a mixture of hypericum oil (hypericum perforatum l.) and neem oil (azadirachta indica a. juss.), in scalp wounds with exposed bone. | 2014 | 24851844 |
| effect of oxidative phytochemicals on nicotine-stressed umnsah/df-1 cell line. | nicotine is a parasympathomimetic alkaloid found in the nightshade family of plants (solanaceae) and is a cholinergic drug. it acts directly by stimulating the nicotinic or muscarinic receptors or indirectly by inhibiting cholinesterase, promoting acetylcholine release, or by other mechanisms. 3% of tobacco or one cigarette yields 1 mg of nicotine. as nicotine enters the body, it disturbs the healthy functioning of the body. in this study, we isolated umnsah/df-1 cell line from gallus gallus. fo ... | 2014 | 24860736 |
| nimbolide b and nimbic acid b, phytotoxic substances in neem leaves with allelopathic activity. | neem (azadirachta indica) has been widely used as a traditional medicine and several bioactive compounds have been isolated from this species, but to date no potent allelopathic active substance has been reported. therefore, we investigated possible allelopathic property and phytotoxic substances with allelopathic activity in neem. an aqueous methanol extract of neem leaves inhibited the growth of roots and shoots of cress, lettuce, alfalfa, timothy, crabgrass, ryegrass, barnyard grass and jungl ... | 2014 | 24865604 |
| anti-inflammatory and antinociceptive activities of azadirachtin in mice. | azadirachta indica (meliaceae) extracts have been reported to exhibit anti-inflammatory and antinociceptive properties. however, the activities of azadirachtin, a limonoid and the major bioactive compound found in the extracts, have been poorly investigated in animal models. in the present study, we investigated the effects induced by azadirachtin in experimental models of pain and inflammation in mice. carrageenan-induced paw edema and fibrovascular tissue growth induced by subcutaneous cotton ... | 2014 | 24871207 |
| guaiane sesquiterpenes and isopimarane diterpenes from an endophytic fungus xylaria sp. | nine oxygenated guaiane-type sesquiterpenes and three isopimarane diterpenes were isolated from the culture broth of an endophytic fungus, xylaria sp. ym 311647, obtained from azadirachta indica. the structures of these compounds were elucidated by interpretation of spectroscopic data. the absolute configurations of two of these were confirmed by x-ray crystallographic analysis. all of the compounds were tested for their antifungal activities against five pathogenic fungal cells. the results sho ... | 2014 | 24890390 |
| traditional uses of medicinal plants against malarial disease by the tribal communities of lesser himalayas-pakistan. | malaria is among the most prevalent infectious diseases in the developing countries of world. estimated number of annual malaria episodes in pakistan is 1.5 million, but very little is known about medicinal plant species of pakistan, which have great potential against malarial disease. present study was aimed to document medicinal plant species used by the local inhabitants of lesser himalayas-pakistan to treat malaria. | 2014 | 24892831 |
| archives of total mercury reconstructed with ice and snow from greenland and the canadian high arctic. | this study reports total hg concentration and atmospheric flux data from ice cores and snow/ice shallow pits from two canadian arctic and one greenland glaciers, with the aim of reconstructing a high resolution record of thg deposition extending back into the pre-industrial period. an 88-m ice core (653 samples) from the neem glacier site in northwest greenland was retrieved in august 2010. the bottom sample was dated to 1748, resulting in a 262 year archive. snow and ice samples (143 samples) w ... | 2015 | 24913889 |
| phytoremediation of abandoned crude oil contaminated drill sites of assam with the aid of a hydrocarbon-degrading bacterial formulation. | environmental deterioration due to crude oil contamination and abandoned drill sites is an ecological concern in assam. to revive such contaminated sites, afield study was conducted to phytoremediate four crude oil abandoned drill sites of assam (gelakey, amguri, lakwa, and borholla) with the aid of two hydrocarbon-degrading pseudomonas strains designated n3 and n4. all the drill sites were contaminated with 15.1 to 32.8% crude oil, and the soil was alkaline in nature (ph8.0-8.7) with low moistu ... | 2014 | 24933892 |
| vinegar as a disinfectant of extracted human teeth for dental educational use. | extracted human teeth are routinely used in dentistry to learn technical and preclinical skills. centers for disease control and prevention (cdc) has adopted guidelines for infection control of extracted teeth used for research and teaching, requiring that teeth be sterilized before use. many of the proposed disinfection methods starting from use of formalin, sodium hypochlorite and to autoclaving have their own drawbacks and may not be practical. | 2014 | 24959031 |
| neemdb: convenient database for neem secondary metabolites. | indian neem tree is known for its pesticidal and medicinal properties for centuries. structure elucidation of large number of secondary metabolites responsible for its diverse properties has been achieved. however, this data is spread over various books, scientific reports and publications and difficult to access. we have compiled and stored structural details of neem metabolites in neemdb, a database which can be easily accessed, queried and downloaded. neemdb would be central in dissipating st ... | 2014 | 24966540 |
| the antimicrobial activity of azadirachta indica, mimusops elengi, tinospora cardifolia, ocimum sanctum and 2% chlorhexidine gluconate on common endodontic pathogens: an in vitro study. | to check the antimicrobial activity of azadirachta indica (neem), ocimum sanctum (tulsi), mimusops elelngi (bakul), tinospora cardifolia (giloy) and chlorhexidine gluconate (chx) on common endodontic pathogens like streptococcus mutans, enterococcus faecalis and staphylococcus aureus. | 2014 | 24966766 |
| studies on the acaricidal mechanism of the active components from neem (azadirachta indica) oil against sarcoptes scabiei var. cuniculi. | octadecanoic acid-3,4-tetrahydrofuran diester, isolated from neem (azadirachta indica) oil, exhibited potent acaricidal activity against sarcoptes scabiei var. cuniculi. in this paper, the acaricidal mechanism of octadecanoic acid-3,4-tetrahydrofuran diester against sarcoptes scabiei var. cuniculi was evaluated based on pathologic histology and enzyme activities. the results showed that after compound treatment for 24h at a concentration of 20mg/ml, the lesions of mites were prominent under tran ... | 2014 | 24974121 |
| "herbal remedy is natural and safe"--truth or myth? | neem oil is often used externally as a traditional medicine in india. its ingestion, even in small doses produces toxic effects like severe metabolic acidosis, seizures, renal failure and encephalopathy. management is supportive and prognosis is generally good but fatalities may occur. herein we report an unusual case of neem oil toxicity in a previously normal adult. | 2013 | 24974507 |
| azadirachta indica attenuates cisplatin-induced neurotoxicity in rats. | the objective of this study is to investigate the neuroprotective effects of azadirachta indica leaves against cisplatin (cp)-induced neurotoxicity. | 2017 | 24987180 |
| solubility and bioavailability enhancement of poorly aqueous soluble atorvastatin: in vitro, ex vivo, and in vivo studies. | the objective of this investigation was to improve the solubility of the poorly water soluble drug atorvastatin (atr), using solid dispersion (sd) techniques, with neem gum (ng) as a hydrophilic carrier. the effects of the polymer concentration and method of preparation on the solubility and dissolution rate were studied. the results showed that the solubility of atr increases with increasing ng concentration. however, dissolution rate of atr from its sd was dependent on the method used to prepa ... | 2014 | 24995297 |
| anti-mosquito plants as an alternative or incremental method for malaria vector control among rural communities of bagamoyo district, tanzania. | plants represent one of the most accessible resources available for mosquito control by communities in tanzania. however, no documented statistics exist for their contribution in the management of mosquitoes and other insects except through verbal and some publications. this study aimed at assessing communities' knowledge, attitudes and practices of using plants as an alternative method for mosquito control among selected communities in a malaria-prone area in tanzania. | 2014 | 25015092 |
| neem components as potential agents for cancer prevention and treatment. | azadirachta indica, also known as neem, is commonly found in many semi-tropical and tropical countries including india, pakistan, and bangladesh. the components extracted from neem plant have been used in traditional medicine for the cure of multiple diseases including cancer for centuries. the extracts of seeds, leaves, flowers, and fruits of neem have consistently shown chemopreventive and antitumor effects in different types of cancer. azadirachtin and nimbolide are among the few bioactive co ... | 2014 | 25016141 |
| beneficial effect of azadirachta indica on advanced glycation end-product in streptozotocin-diabetic rat. | both oxidation and hyperglycemia cause increased glycation and the formation of advanced glycation end-products (ages) which underlie the complications of diabetes. | 2014 | 25026338 |
| multi-constituent synergism is responsible for anti-inflammatory effect of azadirachta indica leaf extract. | azadirachta indica a. juss. (meliaceaes) leaves have been used traditionally to treat swelling and rheumatism in indian cultures. | 2014 | 25026347 |
| three new and other limonoids from the hexane extract of melia azedarach fruits and their cytotoxic activities. | a defatted fraction obtained from the hexane extract of the fruits of melia azedarach l. (chinaberry tree; meliaceae) exhibited cytotoxic activities against leukemia (hl60), lung (a549), stomach (az521), and breast (sk-br-3) cancer cell lines with ic50 values in the range of 2.9-21.9 μg/ml. three new limonoids, 3-deacetyl-4'-demethylsalannin (5), 3-deacetyl-28-oxosalannin (14), and 1-detigloylohchinolal (17), along with 16 known limonoids, 1-4, 6-13, 15, 16, 18, and 19, and one known triterpenoi ... | 2014 | 25044585 |
| peltate glandular trichomes of colquhounia seguinii harbor new defensive clerodane diterpenoids. | glandular trichomes produce a wide variety of secondary metabolites that are considered as major defensive chemicals against herbivore attack. the morphology and secondary metabolites of the peltate glandular trichomes of a lianoid labiatae, colquhounia seguinii vaniot, were investigated. three new clerodane diterpenoids, seguiniilactones a-c (1-3), were identified through precise trichome collection with laser microdissection, metabolic analysis with ultra performance liquid chromatography-tand ... | 2014 | 25048077 |
| investigation of total phenolic content and antioxidant activities of azadirachta indica roots. | the present study was an attempt to study total phenolic content and antioxidant property of the crude ethanolic extract of the roots of azadirachta indica (a. indica). | 2014 | 25050306 |
| ethanolic extract of azadirachta indica (a. juss.) causing apoptosis by ros upregulation in dirofilaria immitis microfilaria. | dirofilaria immitis is the causative agent of cardiopulmonary dirofilariasis in the canine family. the aim of the study was to evaluate the efficacy of the ethanolic extract of azadirachta indica leaves (eea) against the microfilaria (mf) of d. immitis in vitro. eea was evaluated for different compound classes through hptlc. relative motility, mortality and morphological alterations were observed in the mf after exposure to eea. the effect of eea on redox status in the treated mf was evaluated b ... | 2014 | 25092478 |
| laboratory and field efficacy of entomopathogenic fungi for the management of the sweetpotato weevil, cylas formicarius (coleoptera: brentidae). | the sweetpotato weevil, cylas formicarius (f.) (coleoptera: brentidae), is one of the most important pests of sweet potatoes in the world. with free trade between the united states and the u.s.-controlled mariana islands, c. formicarius has spread along with this commodity. because of the cryptic nature of the larvae and nocturnal activity of the adults, and the cancellation of long-residual pesticides, this pest has become increasingly difficult to control. therefore, the present study sought t ... | 2014 | 25111763 |
| cumulative mortality of aedes aegypti larvae treated with compounds. | objective to evaluate the larvicidal activity of azadirachta indica, melaleuca alternifolia, carapa guianensis essential oils and fermented extract of carica papaya against aedes aegypti (linnaeus, 1762) (diptera: culicidae). methods the larvicide test was performed in triplicate with 300 larvae for each experimental group using the third larval stage, which were exposed for 24h. the groups were: positive control with industrial larvicide (bti) in concentrations of 0.37 ppm (pc1) and 0.06 ppm (p ... | 0 | 25119939 |
| murine carcinoma expressing carcinoembryonic antigen-like protein is restricted by antibody against neem leaf glycoprotein. | we have generated a polyclonal antibody against a novel immunomodulator, neem leaf glycoprotein (nlgp) that can react to a specific 47 kda subunit of nlgp. generated anti-nlgp antibody (primarily igg2a) was tested for its anti-tumor activity in murine carcinoma (ec, ct-26), sarcoma (s180) and melanoma (b16mel) tumor models. surprisingly, tumor growth restriction was only observed in ct-26 carcinoma models, without any alteration in other tumor systems. comparative examination of antigenicity bet ... | 2014 | 25128841 |
| morphological alterations in the synganglion and integument of rhipicephalus sanguineus ticks exposed to aqueous extracts of neem leaves (azadirachta indica a. juss). | currently, the necessity of controlling infestation by ticks, especially by rhipicephalus sanguineus, has led researchers and public health managers around the world to search for new and more efficient control methods. this way, we can highlight neem (azadirachta indica a. juss) leaf, bark, and seed extracts, which have been very effective on tick control, and moreover causing less damage to the environment and to the host. this study showed the potential of neem as a control method for r. sang ... | 2014 | 25130979 |
| silver nanoparticles: a possibility for malarial and filarial vector control technology. | green synthesis technology is one of the rapid, reliable and best routes for the synthesis of silver nanoparticles (agnps). there are bioactive compounds with enormous potential in azadirachta indica (neem). the extraordinary mosquitoes warrant nanotechnology to integrate with novel molecules. this will be sustainable technology for future. here, we synthesized agnps using aqueous extracts of leaves and bark of az. indica (neem). we tested agnps as larvicides, pupicides and adulticides against t ... | 2014 | 25132567 |
| management of mango hopper, idioscopus clypealis, using chemical insecticides and neem oil. | an experiment was conducted in field laboratory, department of entomology at bangladesh agricultural university, mymensingh, during 2013 to manage the mango hopper, idioscopus clypealis l, using three chemical insecticides, imidacloprid (0.3%), endosulfan (0.5%), and cypermethrin (0.4%), and natural neem oil (3%) with three replications of each. all the treatments were significantly effective in managing mango hopper in comparison to the control. imidacloprid showed the highest efficacy in perce ... | 2014 | 25140344 |
| comparative immunomodulation potential of tinospora cordifolia (willd.) miers ex hook. f., tinospora sinensis (lour.) merrill and tinospora cordifolia growing on azadirachta indica a. juss. | guduchi has been widely used in the traditional medicine as an immunomodulator. description of guduchi in ayurvedic literature resemble with t. sinensis rather than with commonly available t. cordifolia and hence this may be used as substitutes for t. sinensis. t. cordifolia growing on azadirachta indica commonly called neem-guduchi has more immunomodulatory potential. thus, immunomodulatory activity of three tinospora spp. was assessed by checking humoral and cell mediated immune responses to t ... | 2014 | 25141544 |
| apoptosis-inducing effect of three medicinal plants on oral cancer cells kb and orl-48. | brucea javanica, azadirachta indica, and typhonium flagelliforme are medicinal plants commonly used to treat conditions associated with tumour formation. this study aimed to determine the antiproliferative activity of these plants extracts on kb and orl-48 oral cancer cell lines and to suggest their mode of cell death. the concentration producing 50% cell inhibition (ic50) was determined and the activity was examined under an inverted microscope. immunohistochemistry fluorescent staining method ... | 2014 | 25147833 |
| azadirachta indica attenuates cisplatin-induced nephrotoxicity and oxidative stress. | we investigated the effects of methanolic leaves extract of azadirachta indica (mlen, 500 mg/kg bwt) on cisplatin- (cp-) induced nephrotoxicity and oxidative stress in rats. cp (5 mg/kg bwt) was injected intraperitoneally and mlen was given by gastric gavage for 5 days before or after cp injection. after 5 days of cp injection, cp-induced injury of the renal tissue was evidenced (i) as histopathological damage of the renal tissue, (ii) as increases in serum uric acid, urea, and creatinine, (iii) ... | 2014 | 25162019 |
| useful ethnophytomedicinal recipes of angiosperms used against diabetes in south east asian countries (india, pakistan & sri lanka). | this paper is based on data recorded from various literatures pertaining to ethnophytomedicinal recipes used against diabetes in south east asia (india, pakistan and srilanka). traditional plant treatments have been used throughout the world for the therapy of diabetes mellitus. in total 419 useful phytorecipes of 270 plant species belonging to 74 angiospermic families were collected. from the review it was revealed that plants showing hypoglycemic potential mainly belong to the families, cucurb ... | 2014 | 25176368 |
| effect of traditionally used neem and babool chewing stick (datun) on streptococcus mutans: an in-vitro study. | there are various plants, which are used as chewing sticks in different parts of the world. several studies have been reported on the antimicrobial effects of chewing sticks on oral bacteria. this study was conducted to evaluate the effectiveness of traditionally used neem and babool chewing sticks (datun) extracts on streptococcus mutans. | 2014 | 25177629 |
| neem (azadirachta indica l.) leaf extract deteriorates oocyte quality by inducing ros-mediated apoptosis in mammals. | neem (azadirachta indica l.) leaf has been widely used in ayurvedic system of medicine for fertility regulation for a long time. the molecular mechanism by which neem leaf regulates female fertility remains poorly understood. animal studies suggest that aqueous neem leaf extract (nle) induces reactive oxygen species (ros) - mediated granulosa cell apoptosis. granulosa cell apoptosis deprives oocytes from nutrients, survival factors and cell cycle proteins required for the achievement of meiotic ... | 2014 | 25197620 |
| a monoclonal antibody against neem leaf glycoprotein recognizes carcinoembryonic antigen (cea) and restricts cea expressing tumor growth. | carcinoembryonic antigen (cea) is one of the promising tumor antigens mainly associated with carcinoma of the colon, lung, breast, etc. and received wide attention for cancer immunotherapy. neem leaf glycoprotein (nlgp), an effective immunomodulator, is able to generate humoral and cellular immune responses in murine tumor models. we have generated a monoclonal antibody (mab) against nlgp by fusing nlgp-immunized mice splenocytes with nonsecretory myeloma cells. a highly anti-nlgp mab secreting ... | 2014 | 25198527 |
| studies on repellent activity of seed oils alone and in combination on mosquito, aedes aegypti. | the study was undertaken to investigate the relative repellency of pongamia pinnata and azadirachta indica seed oils on vector mosquito, aedes aegypti under laboratory conditions. the repellents were formulated into 3 groups: seed oils, their mixture and combination of seed oils with three carrier oils viz. olive, mustard and coconut oil. different formulations of each oil were tested at the concentrations of 1% and 5% on human baits. efficiency was assessed, based on the total protection time; ... | 2014 | 25204067 |
| characteristics of tomato plants treated with leaf extracts of neem (azadirachta indica a. juss. (l.)) and mata-raton (gliricidia sepium (jacquin)): a greenhouse experiment. | extracts of neem (azadirachta indica a.) and mata-raton (gliricidia sepium) leaves were used as insect repellent during organic cultivation of tomato plants (solanum lycopersicum) and were compared with untreated plants or plants treated with lambda-cyhalothrin (chemical treatment). the best developed tomato plants were found in the gliricidia treatment, while difference between other treatments were small. the number of different species of macrofauna found on tomato plants were similar in diff ... | 2014 | 25204070 |
| botanicals, selective insecticides, and predators to control diaphorina citri (hemiptera: liviidae) in citrus orchards. | the asian citrus psyllid (acp) diaphorina citri kuwayama vectors pathogens that cause huanglongbing (hlb) or citrus greening devastating and economically important disease present in most citrus growing regions. young citrus shoots are required for psyllid reproduction and development. during winter citrus trees produce little or no new growth. overwintering adults reproduce in spring on newly emerging shoots also attractive to other pests and beneficial insects. botanicals and relatively select ... | 2014 | 25205398 |
| antibacterial activity of aqueous extracts of indian chewing sticks on dental plaque: an in vitro study. | the anti-microbial efficacy of aqueous extracts of indian chewing sticks against different kinds of plaque bacteria in vitro was investigated. supra-gingival plaque is cultured and subjected to the antibacterial activity of the aqueous extracts of chewing sticks (neem, acacia, pongamia glabra, achyranthes aspera, streblus asper) separately. the results of the study demonstrate that all the five chewing sticks under study possess inhibitory potential against bacteria present in dental plaque main ... | 2014 | 25210357 |
| indian culinary plants enhance glucose-induced insulin secretion and glucose consumption in ins-1 β-cells and 3t3-l1 adipocytes. | six indian plants, commonly used as culinary plants, herbs or spices (kikar; jamun; neem; harad; fenugreek; bitter gourd), were screened and compared for their antidiabetic potential in vitro. aqueous plant extracts were prepared and assessed for their effect on the insulin secretion activity of rat pancreatic ins-1 β-cells and glucose consumption in mouse 3t3-l1 adipocytes in order to study their specific mechanisms of action. the effect of the plant extract concentration (25-1000μg/ml) on insu ... | 2011 | 25212346 |
| synthesis of silver nanoparticles from azadirachta indica--a most effective method for mosquito control. | mosquitoes transmit major communicable diseases such as dengue, malaria, filariasis, japanese encephalitis, chikungunya, and so on. vector control is important in epidemic disease situations as there is an urgent need to develop new and improved mosquito control methods that are economical and effective yet safe for non-targeted organisms. in the present study, silver nanoparticles (agnps) were synthesized from the aqueous leaf extract of neem plant (azadirachta indica), and their effects on mos ... | 2015 | 25226837 |
| 10be climate fingerprints during the eemian in the neem ice core, greenland. | several deep greenland ice cores have been retrieved, however, capturing the eemian period has been problematic due to stratigraphic disturbances in the ice. the new greenland deep ice core from the neem site (77.45 °n, 51.06 °w, 2450 m.a.s.l) recovered a relatively complete eemian record. here we discuss the cosmogenic (10)be isotope record from this core. the results show eemian average (10)be concentrations about 0.7 times lower than in the holocene which suggests a warmer climate and approxi ... | 2014 | 25266953 |
| expedient preparative isolation and tandem mass spectrometric characterization of c-seco triterpenoids from neem oil. | c-seco triterpenoids are widely bioactive class of natural products with high structural complexity and diversity. the preparative isolation of these molecules with high purity is greatly desirable, although restricted due to the complexity of natural extracts. in this article we have demonstrated a medium pressure liquid chromatography (mplc) based protocol for the isolation of eight major c-seco triterpenoids of salannin skeleton from neem (azadirachta indica) oil. successive application of no ... | 2014 | 25267707 |
| effect of aqueous extract of azadirachta indica a. juss (neem) leaf on oocyte maturation, oviposition, reproductive potentials and embryonic development of a freshwater fish ectoparasite argulus bengalensis ramakrishna, 1951 (crustacea: branchiura). | in present study, a microcosm experiment is carried out to investigate the efficacy of 120 and 250-ppm crude aqueous extract of azadirachta leaf on oocyte maturation, oviposition, embryonic development and hatching of the eggs of a fish ectoparasite argulus bengalensis. relative abundance of different maturing oocyte stages in the ovary of the parasite from different age groups was enumerated, and marked variations were obtained. significant depletion in the abundance of pre-vitollogenic, vitell ... | 2014 | 25270235 |
| natural control of bacteria affecting meat quality by a neem (azadirachta indica a. juss) cake extract. | the antibacterial activity of an ethylacetate neem cake extract (nce) against bacteria that affect meat quality, namely campylobacter jejuni, carnobacterium spp., lactobacillus curvatus, lactobacillus sakei and leuconostoc sp., is reported. the antibacterial activity was detected using standardised disc diffusion and macrodilution methods. the bacterial growth inhibition zone ranged from 11.33 ± 0.58 to 22.67 ± 0.58 mm (100 μl nce). there is significant difference between the growth inhibition z ... | 2015 | 25272067 |
| in vitro bioactivity and antimicrobial tuning of bioactive glass nanoparticles added with neem (azadirachta indica) leaf powder. | silica and phosphate based bioactive glass nanoparticles (58sio2-33cao-9p2o5) with doping of neem (azadirachta indica) leaf powder and silver nanoparticles were prepared and characterised. bioactive glass nanoparticles were produced using sol-gel technique. in vitro bioactivity of the prepared samples was investigated using simulated body fluid. x-ray diffraction (xrd) pattern of prepared glass particles reveals amorphous phase and spherical morphology with a particle size of less than 50 nm. wh ... | 2014 | 25276834 |
| biogenic gold nano-triangles: cargos for anticancer drug delivery. | we present synthesis of biogenic gold nano triangles (gnts) using azadirachta indica leaf extract at inherent ph (5.89) and its application in efficient drug delivery of doxorubicin (dox) (anticancer drug). the main idea was to take advantage of large surface area of gnts which has 3 dimensions and use the plant peptides coated on these triangles as natural linkers for the attachment of dox. sucrose density gradient centrifugation (sdgc) and dialysis methods were used for separation of the gnt f ... | 2014 | 25280684 |
| screening the antifungal activity of essential oils against decay fungi from palmyrah leaf handicrafts. | the whitish tender leaves of palmyrah are used for making handicrafts. the problem with these articles is discolouration with time and become more brittle due to fungal attack. this could be prevented by some protective coating. instead of expensive and harmful chemicals we decided to test natural plant essential oils to control fungal attack. palmyrah leaf article decay fungi were isolated from two different sites of jaffna peninsula. in this investigation antifungal activity of different plant ... | 2014 | 25287894 |
| three new limonoids from azadirachta indica. | three new limonoids, azadiraindins e-g (1-3, respectively), together with six known analogs, were isolated from the fresh fruit coats of azadirachta indica. the structures of these compounds were elucidated by spectroscopic methods (ir, ms, hr-esi-ms, 1d nmr, and 2d nmr). | 2015 | 25289883 |
| immunotherapeutic targeting of established sarcoma in swiss mice by tumor-derived antigen-pulsed nlgp matured dendritic cells is cd8+ t-cell dependent. | neem leaf glycoprotein (nlgp) matures human myeloid and mouse bone marrow-derived dendritic cells (dcs). (nlgp) also therapeutically restricts the mouse established sarcoma growth by activating cd8(+) t cells along with increased proportion of tumor residing cd11c(+) dcs. here, we intended to find out whether cd8(+) t cells become cytotoxic to sarcoma cells after presentation of sarcoma antigen by nlgp-matured dcs to restrict murine sarcoma growth. | 2014 | 25290415 |
| [peculicidal activity of plant essential oils and their based preparations]. | the peculicidal activity of eight plant essential oils in 75% isopropyl alcohol was in vitro investigated. of them, the substances that were most active against lice were tea tree (melaleuca), eucalyptus, neem, citronella (cymbopogon nardus), and clove (syzygium aromaticum) oils; kt50 was not more than 3 minutes on average; kt95 was 4 minutes. after evaporating the solvent, only five (tea tree, cassia, clove, anise (anisum vulgare), and japanese star anise (illicium anisatum) oils) of the eight ... | 2014 | 25296426 |
| critical electrolyte concentration of silk gland chromatin of the sugarcane borer diatraea saccharalis, induced using agrochemicals. | the sugarcane borer diatraea saccharalis is widely known as the main pest of sugarcane crop, causing increased damage to the entire fields. measures to control this pest involve the use of chemicals and biological control with cotesia flavipes wasps. in this study, we evaluated the insecticides fipronil (frontline; 0.0025%), malathion (malatol bio carb; 0.4%), cipermetrina (galgotrin; 10%), and neem oil (natuneem; 100%) and the herbicide nicosulfuron (sanson 40 sc; 100%) in the posterior region ... | 2014 | 25299111 |
| [severe poisoning by plants used for traditional medicine in mayotte]. | the authors describe three cases of severe accidental poisoning by plants used as part of a traditional treatment in mayotte. the established, or suspected, toxicity of thevetia peruviana (yellow oleander), cinchona pubescens (red quinine-tree), melia azaderach (persian lilac, also called china berry) and azadirachta indica (neem), is discussed. the clinical presentation is cardiac (atrioventricular block) and well known for thevetia and cinchona intoxications. neurological signs and multi-organ ... | 2014 | 25301110 |
| field evaluation of a botanical formulation from the milky mangrove excoecaria agallocha l. against helicoverpa armigera hübner. in abelmoschus esculentus (lady's finger) and cajanus cajan (pigeon pea). | to evaluate a formulation from the milky mangrove tree excoecaria agallocha l. (e. agallocha) against helicoverpa armigera hubner (h. armigera). | 2014 | 25312115 |
| osmoregulatory and tegumental ultrastructural damages to protoscoleces of hydatid cysts echinococcus granulosus induced by fungal endophytes. | characteristic ultrastructural changes were observed when protoscoleces of hydatid cysts echinococcus granulosus was treated with extract of endophytic fungi eupenicillium and chaetomium sp. isolated from azadirachta indica and piper longum plants respectively. a sharp decrease in viability of protoscoleces was observed after 6 h of incubation with fungal extracts. the ultrastructural changes included rosteller disorganization, loss of hooks and shedding of the microtriches of scolex region. the ... | 2014 | 25320499 |
| larvicidal and ovideterrent properties of neem oil and fractions against the filariasis vector aedes albopictus (diptera: culicidae): a bioactivity survey across production sites. | neem seed oil (nso) of azadirachta indica (meliaceae) contains more than 100 determined biologically active compounds, and many formulations deriving from them showed toxicity, antifeedancy and repellence against a number of arthropod pests. however, it is widely known that botanical products can differ in their chemical composition and bioactivity, as function of the production site and production process. we used high-performance thin layer chromatography (hptlc) to investigate differences in ... | 2015 | 25327954 |
| storage behavior of mango as affected by post harvest application of plant extracts and storage conditions. | the use of plant extracts could be a useful alternative to synthetic fungicides in the post harvest handling of fruits and vegetables. the aim of this study was to access the efficacy of extracts obtained from four plants (neem, pongamia, custard apple leaf and marigold flowers) on the extension of shelf life of mango fruits cv. dashehri under two storage conditions (cool store and ambient condition). the fruits were treated with 2 concentrations of each plant extracts (10 % and 20 %) were place ... | 2014 | 25328189 |
| direct, rapid and sustainable vermicomposting of the leaf litter of neem (azadirachta indica). | the recently developed concept of high rate vermicomposting was successfully used to enable direct vermicomoposting of neem leaves-without any pre-composting or cow dung supplementation as previously reported processes had necessitated. all the three epigeic species of earthworms that were explored, eudrilus eugeniae, eisenia fetida and perionyx excavatus, provided efficient vermicast production with no mortality, persistent gain in body mass and good fecundity over the 16 months long period of ... | 2015 | 25344437 |
| [nutrient accumulation and cycling in pure and mixed plantations of azadirachta indica and acacia auriculiformis in a dry-hot valley, yunnan province, southwest china]. | to ease the implementation of effective nutrient management for plantations with different vegetation restoration patterns and to assist in the selection of appropriate species and forestation patterns, nutrient (n, p, k, ca and mg) accumulation and cycling were investigated and compared in three plantations (10-year-old azadirachta indica, acacia auriculiformis and mixed a. indica--a. auriculiformis plantations) in yuanmou valley, a dry-hot valley of yunnan province, southwestern china. the res ... | 2014 | 25345036 |
| morphological effects of neem (azadirachta indica a. juss) seed oil with known azadirachtin concentrations on the oocytes of semi-engorged rhipicephalus sanguineus ticks (acari: ixodidae). | the concern about the harmful effects caused by synthetic pesticides has led to the search for safe and ecological alternatives for pest control. in this context, the neem tree (azadirachta indica) stands out due to its repellent properties and effects on various arthropods, including ticks. for this reason, this study aimed to demonstrate the potential of neem as a control method for rhipicephalus sanguineus ticks, important vectors of diseases in the veterinary point of view. for this, r. sang ... | 2015 | 25346198 |
| use of plant residues on growth of mycorrhizal seedlings of neem (azadirachta indica a. juss.). | owing to its multiple uses in veterinary medicine, biofertilizers, pest control, etc., the commercial cultivation of neem (azadirachta indica) has been increasing in various countries. the use of arbuscular mycorrhizal fungi (amf) and plant by-products (composted leaves and residues of neem and sugarcane) for the propagation of seedlings can be an efficient alternative to stimulate plant growth, reducing the propagation time and conferring increased tolerance of plants to biotic and abiotic stre ... | 2012 | 25363647 |
| effect of azadirachta indica (neem) and aloe vera as compared to subantimicrobial dose doxycycline on matrix metalloproteinases (mmp)-2 and mmp-9: an in-vitro study. | a critical outcome of periodontal diseases is degradation of collagen in the periodontal tissues, by enzymes such as matrix metallo-proteinases (mmps). doxycycline is known to down-regulate the activity of mmps. azadirachta indica (neem) and aloe vera are herbs known to have an anti-inflammatory effect. the present study was designed to evaluate the anti-inflammatory effect of neem and aloe vera by way of its inhibitory effect on mmp-2 and mmp-9 activity in cases of chronic periodontitis and com ... | 2014 | 25364206 |
| nimbolide inhibits invasion and migration, and down-regulates upar chemokine gene expression, in two breast cancer cell lines. | breast cancer is the most frequently diagnosed cancer and the leading cause of cancer death in women, worldwide. urokinase type plasminogen activator (upa) is a serine protease that is involved in cancer progression, especially invasion and metastasis of breast cancer. nimbolide is a potent cytotoxic limnoid isolated from azadirachta indica. our previous studies have shown that nimbolide elicits pleiotropic effects on breast cancer cells; however, its roles in invasion and migration have not pre ... | 2014 | 25377085 |