Publications
| Title | Abstract | Year Filter | PMID(sorted ascending) Filter |
|---|
| trichophyton species of arthroderma benhamiae - a new infectious agent in dermatology. | in germany, infections due to the zoophilic dermatophyte trichophyton (t.) species of arthroderma benhamiae are being more frequently diagnosed. the source of infection of this emerging pathogen overlaps with that of the zoophilic species t. interdigitale. the most common source are guinea pigs. t. species of arthroderma benhamiae causes inflammatory dermatophytosis in children and adolescents. in addition to tinea capitis, it may cause both tinea corporis, tinea manus and frequently tinea facie ... | 2014 | 24981469 |
| tinea capitis caused by microsporum canis infection in a 75-years-old woman. | 2014 | 24990278 | |
| multiorgan fungal infection caused by microsporum canis in a green iguana (iguana iguana). | multiple organ invasion by keratinophilic fungi in the green iguana (iguana iguana) has not been previously reported. in this case, a 1-yr-old female green iguana presented with a nodular, darkly discolored skin lesion surrounded by necrosis in the right ventral abdominal region. a cytologic examination of the fine needle aspiration of the lesion revealed an exuberant proliferation of fibroblasts, macrophages, and multinucleated cells along with frequent filamentous structures consistent with hy ... | 2014 | 25000705 |
| management of endemic microsporum canis dermatophytosis in an open admission shelter: a field study. | endemic microsporum canis dermatophytosis was identified in a large, open admission, private, no-kill shelter that admitted >1200 cats per year. fungal culture (fc) screening revealed that 166/210 (79%) and 38/99 (38%) cats in the non-public and public area were culture positive, respectively. however, pending screening fc results, the 99 cats in the public area were treated with once-weekly lime sulfur rinses and monitored with once-weekly fc. cats in the non-public area were not treated. when ... | 2015 | 25074567 |
| lawsonia inermis-mediated synthesis of silver nanoparticles: activity against human pathogenic fungi and bacteria with special reference to formulation of an antimicrobial nanogel. | lawsonia inermis mediated synthesis of silver nanoparticles (ag-nps) and its efficacy against candida albicans, microsporum canis, propioniabacterium acne and trichophyton mentagrophytes is reported. a two-step mechanism has been proposed for bioreduction and formation of an intermediate complex leading to the synthesis of capped nanoparticles was developed. in addition, antimicrobial gel for m. canis and t. mentagrophytes was also formulated. ag-nps were synthesized by challenging the leaft ext ... | 2014 | 25082226 |
| alkylphenol activity against candida spp. and microsporum canis: a focus on the antifungal activity of thymol, eugenol and o-methyl derivatives. | in recent years there has been an increasing search for new antifungal compounds due to the side effects of conventional antifungal drugs and fungal resistance. the aims of this study were to test in vitro the activity of thymol, eugenol, estragole and anethole and some o-methyl-derivatives (methylthymol and methyleugenol) against candida spp. and microsporum canis. the broth microdilution method was used to determine the minimum inhibitory concentration (mic). the minimum fungicidal concentrati ... | 2011 | 25134762 |
| antifungal activity of pomegranate peel extract and isolated compound punicalagin against dermatophytes. | dermatophyte species infect the epidermis and appendages, often with serious social and health-economic consequences. the hydroalcoholic extract of pomegranate fruit peel showed activity against the dermatophyte fungi trichophyton mentagrophytes, t. rubrum, microsporum canis and m. gypseum. | 2014 | 25260038 |
| in vitro antifungal potentials of bioactive compound oleic acid, 3-(octadecyloxy) propyl ester isolated from lepidagathis cristata willd. (acanthaceae) inflorescence. | to identify bioactive compound oleic acid, 3-(octadecyloxy) propyl ester from lepidagathis cristata willd. (l. cristata) and to assess antifungal potentials of the isolated compound. | 2014 | 25312119 |
| antifungal and cytotoxic activities of nannorrhops ritchiana roots extract. | this atudy was designed to evaluate the antifungal and cytotoxic activities of the nannorrhops ritchiana (mazari palm) 80% methanol extract (nr-m) and its four crude extracts i.e., petroleum ether (nr-a), dichloromethane (nr-b), ethyl acetate (nr-c) and butanol (nr-d). the antifungal activity was determined by agar tube dilution method against nine fungal strains; aspergillus flavus, trichophyton longifusis, trichophyton mentagrophytes, aspergillus flavus and microsporum canis were susceptible t ... | 2014 | 25362807 |
| an ancient plant lawsonia inermis (henna): determination of in vitro antifungal activity against dermatophytes species. | world is endowed with a rich wealth of medicinal plants. there is a widespread belief that green medicines are healthier and more harmless or safer than synthetic ones. medicinal plants have been used to cure a number of diseases. the ancient plant lawsonia inermis or henna is used as medicinal plant because of its attributed strong fungicidal, anti-inflammatory, analgesic, antibacterial, virucidal, antiparasitic, antiamoebiasis, astringent, antihemorrhagic, hypotensive, sedative, anticancer eff ... | 2014 | 25442917 |
| evaluation of antifungal activities of the essential oil and various extracts of nigella sativa and its main component, thymoquinone against pathogenic dermatophyte strains. | plant extracts and plant-derived compounds are valuable sources as folk medicine for the treatment and prevention of a wide range of diseases including infectious diseases. in the present study, the antifungal activities of the essential oil and various extracts nigella sativa and its active principle, thymoquinone against trichophyton mentagrophytes, microsporum canis and microsporum gypseum as pathogenic dermatophyte strains have been evaluated. in addition, the cytotoxic effects of n. sativa ... | 2014 | 25442918 |
| myrtus communis l. as source of a bioactive and safe essential oil. | in algeria, myrtus communis l. is distributed throughout the tell atlas and the coastal regions of algiers and constantine. the leaves are used in respiratory disorders, diarrhea and hemorrhoids. the aims of this work were to evaluate the antifungal and anti-inflammatory potential of well characterized essential oils (eo). since eo can be applied by inhalation, dermal application and oral administration, we used several mammalian cell lines to assess safe bioactive doses. the chemical compositio ... | 2015 | 25446467 |
| the anti-dermatophyte activity of allium hirtifolium boiss aqueous extract. | in an attempt at demonstrating the efficacy of allium hirtifolium aqueous extract in control of skin fungal infections as traditional use, we evaluated the anti-dermatophyte activities of a. hirtifolium aqueous extract from bulbs and of ketoconazole against trichophyton rubrum, trichophyton mentagrophytes, microsporum canis, m. gypseum, trichophyton schoenleinii and trichophyton verrucosum var. album by food poisoning technique, disc diffusion and micro broth dilution assays. the anti-fungal act ... | 2015 | 25456419 |
| hemolytic activity of dermatophytes species isolated from clinical specimens. | hemolytic activity was recently reported for several pathogenic fungal species, such as aspergillus, candida, trichophyton, penicillium and fusarium. based on a number of mechanistic and characterization studies, several fungal hemolysins have been proposed as virulence factors. hemolysins lyse red blood cells resulting in the release of iron, an important growth factor for microbes especially during infection. the requirement of iron in fungal growth is necessary for metabolic processes and as ... | 2015 | 25467819 |
| newly described features resulting from high-magnification dermoscopy of tinea capitis. | recent studies have reported "comma hairs" as a typical dermoscopic feature of tinea capitis observed at low magnification (×10). the aim of this study was to evaluate the dermoscopic aspects of tinea capitis at high magnification (×150) and its diagnostic role. | 2015 | 25471133 |
| synthesis and fungistatic activity of aryl aldoxime derivatives. | the antifungal activity of 13 arylaldoxime ester and ether derivatives was tested against 4 dermatophytes trichophyton mentagrophytes (tm), microsporum canis (mc); m. cookei, and m. gypseum. | 2015 | 25499806 |
| assessment of immunogenicity and protective efficacy of microsporum canis secreted components coupled to monophosphoryl lipid-a adjuvant in a vaccine study using guinea pigs. | microsporum canis is the most common dermatophyte in pets and is of zoonotic importance but currently there is no effective vaccine available to prevent dermatophytosis. the aim of this work was to assess the immunogenicity and protective efficacy of secreted components (sc) from m. canis adjuvanted with the monophosphoryl lipid-a (mpla), in a vaccine study using the guinea pig as an experimental model. animals were vaccinated with either the sc adjuvanted with the mpla, the mpla adjuvant alone ... | 2015 | 25532779 |
| application of microsatellite-primed pcr (msp-pcr) and pcr melting profile (pcr-mp) method for intraspecies differentiation of dermatophytes. | in this study, two pcr-based methods (msp-pcr and pcr-mp) were compared for their abilities to identify intraspecies variations of 23 isolates of trichophyton rubrum, 78 isolates of trichophyton interdigitale and 22 isolates of microsporum canis, obtained mainly from patients in lódź city. the results allowed to distinguish four types (containing two subtypes) characteristic for t. interdigitale and three types characteristic for t. rubrum using pcr-mp method. analysis conducted using msp-pcr wi ... | 2014 | 25546938 |
| phenotypical and molecular characterization of microsporum canis strains in north-tunisia. | in this study, 40 microsporum canis isolates were obtained from different patients from the mycology unit of the hospital la rabta (tunis) during a 3 month period. the phenotypic identification was done by morphological characterization and biochemical tests. molecular analysis was performed by amplification of the its region of rdna, the amplified region was subjected to enzymatic digestion and sequenced to evaluate phylogenetic relationships. the morphological analysis showed a considerable di ... | 2014 | 25546941 |
| molecular identification of fungal pathogens in nodular skin lesions of cats. | in a retrospective study, we investigated 52 formalin-fixed, paraffin-embedded (ffpe) samples from cats with histologically confirmed cutaneous and subcutaneous mycoses to determine if the pathogens could be identified by molecular methods. aim of the study was to obtain a deep understanding of the spectrum of infectious agents, which, as we hypothesized, was not available by histopathology alone. detection of feline and fungal dna was achieved in 92.3% and 94.2% of the samples, respectively. mo ... | 2015 | 25550386 |
| phytochemical characterization, antimicrobial activity, and antioxidant potential of equisetum hyemale l. (equisetaceae) extracts. | equisetum hyemale species is considered a medicinal plant used in the form of infusions to combat infectious or inflammation diseases and also diuretic effects, presenting several compounds related to these actions. in previous studies different species of equisetum showed several phenolic compounds. the objective of this study was, for the first time, based on phytochemistry analysis to evaluate the antioxidant and antimicrobial activity. the 70% ethanolic and methanolic extracts of e. hyemale ... | 2015 | 25587637 |
| investigation of in vitro activity of five antifungal drugs against dermatophytes species isolated from clinical samples using the e-test method. | dermatomycosis is an infection with fungi related to the skin: glabrous skin, hair and/or nails. oral treatment of fungal infections in dermatology has become a preferred modality for the management of these very common conditions. although there are increasing numbers of antifungals available for treatment of dermatophytes, some cases and relapses have been unresponsive to treatment. the determination of fungus in-vitro antifungal susceptibility has been reported to be important for the ability ... | 2014 | 25610290 |
| antimicrobial and antioxidant activities and chemical characterization of essential oils of thymusvulgaris, rosmarinus officinalis, and origanum majorana from northeastern méxico. | there have been no reports of antifungal activity and composition of extracts from thymus vulgaris, rosmarinus officinalis or origanum majorana from northeastern méxico. antifungal activity of these oils against trichophyton rubrum, trichophyton tonsurans, trichophyton mentagrophytes, microsporum gypseum, microsporum canis and epidermophyton floccosum was measured by diffusion assay. additionally, antibacterial and antioxidant activities were evaluated. antibacterial activity against staphylococ ... | 2015 | 25631514 |
| clinical features of 80 cases of tinea faciei treated at a rural clinic in japan. | from march 2008 through february 2014, 80 patients aged 1-95 years (43 men and 37 women) were diagnosed with tinea faciei by a rural japanese clinic. the affected sites were the cheek in 42 patients (52.5%), the auricles and area surrounding the auricles in 16 (20.0%), and the mandible in 12 (15.0%); 33 patients (41.2%) had concurrent ringworm in areas other than the face. twenty-one patients (26.3%) had applied topical steroids to treat a rash. the pathogen responsible for tinea faciei was tric ... | 2014 | 25639303 |
| incidence and etiological agents of genital dermatophytosis in males. | to determine the incidence and etiological agents of dermatophytosis of male genitalia in sarajevo area, bosnia and herzegovina, during a 5-year period (2009-2013). | 2015 | 25669337 |
| therapeutic switching: from antidermatophytic essential oils to new leishmanicidal products. | this study examined whether the antidermatophytic activity of essential oils (eos) can be used as an indicator for the discovery of active natural products against leishmania amazonensis. the aerial parts of seven plants were hydrodistilled. using broth microdilution techniques, the obtained eos were tested against three strains of dermatophytes (trichophyton mentagrophytes, microsporum gypseum and microsporum canis). to compare the eos antifungal and antiparasitic effects, the eos activities ag ... | 2015 | 25714080 |
| design, synthesis and in vitro bactericidal/fungicidal screening of some vanadyl(iv)complexes with mono- and di-substituted ons donor triazoles. | a new series of anti-bacterial and anti-fungal mono- and di-substituted triazoles (l(1))-(l(6)) have been synthesized and characterized on the basis of their physical, spectral and analytical data. the ligands (l(1))-(l(6)) on reaction with vanadyl(iv) sulphate led to the formation of vanadyl(iv) metal complexes (1)-(4). the structure of the complexes has been established on the basis of their physical, spectral and elemental analyses data. the synthesized ligands and their vanadyl(iv) complexes ... | 2015 | 25716124 |
| therapeutic switching: from antidermatophytic essential oils to new leishmanicidal products. | this study examined whether the antidermatophytic activity of essential oils (eos) can be used as an indicator for the discovery of active natural products against leishmania amazonensis. the aerial parts of seven plants were hydrodistilled. using broth microdilution techniques, the obtained eos were tested against three strains of dermatophytes (trichophyton mentagrophytes, microsporum gypseum and microsporum canis). to compare the eos antifungal and antiparasitic effects, the eos activities ag ... | 2015 | 25742270 |
| [in vitro antifungal activity of ravuconazole against isolates of dermatophytes and candida species from patients with dermatomycoses]. | the in vitro activity of ravuconazole (rvcz) was compared with those of itraconazole (itcz) and terbinafine (tbf) against 73 dermatophyte isolates and 18 candida spp. isolates recovered from patients with dermatomycosis at 4 dermatological clinics in japan in 2011. the dermatophyte isolates consisted of trichophyton rubrum (n=51), trichophyton mentagrophytes (n=20 : these strains were not identified by molecular phylogenetic analysis.), trichophyton tonsurans (n=1), and microsporum canis (n=1). ... | 2014 | 25742996 |
| kennel disinfectants for microsporum canis and trichophyton sp. | the antifungal efficacy of commonly used kennel disinfectants for large surfaces was tested using naturally infective material from untreated animals (m. canis and trichophyton sp.) soaked and macerated but unfiltered leaving visible fluorescing hairs and/or scales in the test inoculum to create a robust challenge. disinfectants included sodium hypochlorite (1 : 32 and 1 : 100), enilconazole (1 : 100), accelerated hydrogen peroxide (1 : 16), potassium peroxymonosulfate (1% and 2%), and calcium h ... | 2015 | 25763290 |
| updating the epidemiology of dermatophyte infections in palestine with special reference to concomitant dermatophytosis. | to determine the epidemiology of dermatophytosis in palestinian patients, detect changes in the etiological agents during the last three decades, and to correlate between concomitant tinea pedis infections, and other cutaneous lesions. | 2015 | 25835157 |
| epidemiology of superficial mycoses in northern greece: a 4-year study. | superficial mycoses are defined as the fungal infections of skin, hair or nails that are caused by dermatophytes, yeasts and non-dermatophytic moulds. dermatophytes are the most frequently isolated fungi from specimens of patients with superficial mycoses. | 2016 | 25851424 |
| susceptibility of microsporum canis arthrospores to a mixture of chemically defined essential oils: a perspective for environmental decontamination. | the zoophilic dermatophyte microsporum canis has cats as natural reservoir, but it is able to infect a wide range of hosts, including humans, where different clinical features of the so-called ringworm dermatophytosis have been described. human infections are increasingly been reported in mediterranean countries. a reliable control program against m. canis infection in cats should include an antifungal treatment of both the infected animals and their living environment. in this article, a herbal ... | 2015 | 25854840 |
| digital gene expression analysis of microsporum canis exposed to berberine chloride. | berberine, a natural isoquinoline alkaloid of many medicinal herbs, has an active function against a variety of microbial infections including microsporum canis (m. canis). however, the underlying mechanisms are poorly understood. to study the effect of berberine chloride on m. canis infection, a digital gene expression (dge) tag profiling was constructed and a transcriptome analysis of the m. canis cellular responses upon berberine treatment was performed. illumina/hisseq sequencing technique w ... | 2015 | 25874937 |
| tinea capitis caused by microsporum canis infection in a 75-year-old woman. | 2015 | 25876151 | |
| anti-dermatophyte efficacy and environmental safety of some essential oils commercial and in vitro extracted pure and combined against four keratinophilic pathogenic fungi. | establish new biocontrol practices with low persistence in the environment against dermatophyte causing mycosis. | 2015 | 25953414 |
| design, synthesis, and antifungal activity of new α-aminophosphonates. | α-aminophosphonates are bioisosteres of amino acids and have several pharmacological activities. these compounds have been synthesized by various routes from reaction between amine, aldehyde, and phosphite compounds. in order to synthesize α-aminophosphonates, catalytic effect of cucl2 was compared with fecl3. also all designed structures as well as griseofulvin were docked into the active site of microtubule (1jff), using autodock program. the results showed that the reactions were carried out ... | 2011 | 25954522 |
| biologically active and thermally stable polymeric schiff base and its metal polychelates: their synthesis and spectral aspects. | new metal polychelates of mn(ii), co(ii), ni(ii), cu(ii) and zn(ii) obtained by the interaction of metal acetates with polymeric schiff base containing formaldehyde and piperazine, have been investigated. structural and spectroscopic properties have been evaluated by elemental analysis, ft-ir and (1)h-nmr. geometry of the chelated polymers was confirmed by magnetic susceptibility measurements, uv-visible spectroscopy and electron spin resonance. the molecular weight of the polymer was determined ... | 2015 | 25955762 |
| solid lipid nanoparticles containing copaiba oil and allantoin: development and role of nanoencapsulation on the antifungal activity. | the aim of this work was to develop solid lipid nanoparticles (sln) containing copaiba oil with and without allantoin (ncoa, nco, respectively) and to evaluate their antifungal activity. nanoparticle suspensions were prepared using a high homogenisation technique and characterised by dynamic light scattering, laser diffraction, nanoparticle tracking analysis, multiple light scattering analysis, high-pressure liquid chromatography, ph and rheology. the antifungal activities of the formulations we ... | 2015 | 25980176 |
| dermoscopic features in 12 cats with dermatophytosis and in 12 cats with self-induced alopecia due to other causes: an observational descriptive study. | dermoscopy is a noninvasive technique allowing rapid magnified in vivo observation of the skin and structures that lie beneath the skin surface. various congenital and acquired hair shaft abnormalities may also be evaluated by dermoscopy. additionally, characteristic features of microsporum canis-induced tinea capitis and trichotillomania in humans have been reported. | 2015 | 25988302 |
| decontamination of laundry exposed to microsporum canis hairs and spores. | the objective of this study was to determine the efficacy of decontamination of fabric exposed to microsporum canis hairs and spores by mechanical washing using hot or cold water with or without a sodium hypochlorite additive, and to field test a washing protocol for terry cloth and denim exposed to m canis via direct contact with infected cats. | 2016 | 26012868 |
| antibacterial, antifungal and antioxidant activities of some medicinal plants. | the purpose of this study was to evaluate the antibacterial, antifungal and antioxidant activities of medicinal plants. the antibacterial activity of methanolic extracts of three medicinal plants (swertia chirata, terminalia bellerica and zanthoxylum armatum) were tested against gentamicin (standard drug) on eleven gram positive and seventeen gram negative bacteria by agar well method. it was revealed that seven-gram negative and six gram positive bacterial species were inhibited by these plant ... | 2014 | 26045377 |
| antifungal activity of berberine hydrochloride and palmatine hydrochloride against microsporum canis -induced dermatitis in rabbits and underlying mechanism. | phellodendron amurense, exhibits antifungal activity mainly by bioactive components including berberine hydrochloride and palmatine hydrochloride. this study was conducted to evaluate the antifungal effects of berberine hydrochloride, palmatine hydrochloride, and a mixture of both substances against microsporum canis in vivo and in vitro. | 2015 | 26054937 |
| in vitro activity of the protegrin ib-367 alone and in combination compared with conventional antifungal agents against dermatophytes. | the occurrence of resistance or side effects in patients receiving antifungal agents leads to failure in the treatment of mycosis. the aim of this experimental study was to investigate the in vitro effects of ib-367 alone and in combination with three standard antifungal drugs, fluconazole (flu), itraconazole (itra) and terbinafine (terb), against 20 clinical isolates of dermatophytes belonging to three species. minimum inhibitory concentrations (mics), minimal fungicidal concentrations (mfcs), ... | 2014 | 26058322 |
| in vitro evaluation of enzymatic and antifungal activities of soil-actinomycetes isolates and their molecular identification by pcr. | human cutaneous infection caused by a homogeneous group of keratinophilic fungi called dermatophytes. these fungi are the most common infectious agents in humans that are free of any population and geographic area. microsporum canis is a cause of dermatophytosis (tinea) in recent years in iran and atypical strain has been isolated in iran. its cases occur sporadically due to m. canis transmission from puppies and cats to humans. since this pathogenic dermatophyte is eukaryotes, chemical treatmen ... | 2015 | 26060560 |
| a molecular epidemiological survey of clinically important dermatophytes in iran based on specific rflp profiles of beta-tubulin gene. | surveillance of dermatophytosis is essential to determine the likely changes in etiological trends and distribution profile of this infection. in this study beta tubulin gene (bt2), was used as the first time in a pcr-rflp format to clarify the distribution of dermatophytosis agents in some parts of iran. | 2013 | 26060667 |
| in vitro and in vivo antidermatophytic activities of some iranian medicinal plants. | in the last decades, the number of people suffering from dermatophytoses has seriously increased, which may be due to the development of resistant strains to a range of antifungal drugs. the present study was aimed to evaluate the antidermatophytic properties of eight extracts from the selected spices and herbs, which were ethno-medicinally used in iran against trichophyton mentagrophytes, trichophyton interdigitale, microsporum canis, and microsporum gypseum (10 strain of each). the in vitro an ... | 2015 | 26092105 |
| antidermatophytic activity of mikania micrantha kunth: an invasive weed. | the incidence of dermatophytosis has risen dramatically in recent years. limited availability of side-effect free drugs has led to a search for new antidermatophytic agents. | 2015 | 26109783 |
| [keratinophilic fungi in soils of parks of corrientes city, argentina]. | the soil is a natural reservoir of keratinophilic fungi, which are a small but important group of filamentous fungi, some of which typically develop on keratinized tissues of living animals. there are numerous species of saprophytic fungi with recognized keratinophilic abilities, and several studies have been undertaken in order to link their presence to possible human disease. | 2016 | 26112435 |
| in vitro antifungal activity of some traditional persian medicinal plants on pathogenic fungi. | to investigate the antifungal activities of the extracts and sub-fractions of phlomis olivieri, verbascum speciosum, sambucus ebulus and erigeron hyrcanicus, four persian medicinal plants used in iranian folk medicine. | 2015 | 26129901 |
| a multi-target approach toward the development of novel candidates for antidermatophytic activity: ultrastructural evidence on α-bisabolol-treated microsporum gypseum. | multi-target strategies are directed toward targets that are unrelated (or distantly related) and can create opportunities to address different pathologies. the antidermatophytic activities of nine natural skin lighteners: α-bisabolol, kojic acid, β-arbutin, azelaic acid, hydroquinone, nicotinamide, glycine, glutathione and ascorbyl tetraisopalmitate, were evaluated, in comparison with the known antifungal drug fluconazole, on nine dermatophytes responsible for the most common dermatomycoses: mi ... | 2015 | 26132903 |
| griseofulvin and fluconazole reduce transmission of tinea capitis in schoolchildren. | we evaluated the efficacy of griseofulvin and fluconazole in reducing the potential for person-to-person transmission of tinea capitis (tc) in children. | 2015 | 26215468 |
| epidemiological changes in tinea capitis over the sixty years of economic growth in china. | tinea capitis is a fungal infection of the scalp occurring commonly in children. historical data indicate that clinical manifestations and the spectrum of etiologic agents vary greatly with geography, as well as socioeconomic affected populations. | 2015 | 26260745 |
| dermatophyte and non dermatophyte fungi in riyadh city, saudi arabia. | dermatophytes are a scientific label for a group of three genera (microsporum, epidermophyton and trichophyton) of fungus that causes skin disease in animals and humans. conventional methods for identification of these fungi are rapid and simple but are not accurate comparing to molecular methods. | 2015 | 26288566 |
| inhibitory effect of silver nanoparticles mediated by atmospheric pressure air cold plasma jet against dermatophyte fungi. | in an in vitro study with five clinical isolates of dermatophytes, the mic(50) and mic(100) values of silver nanoparticles (agnps) ranged from 5 to 16 and from 15 to 32 μg ml(- 1), respectively. the combined treatment of agnps with atmospheric pressure-air cold plasma (apacp) induced a drop in the mic(50) and mic100 values of agnps reaching 3-11 and 12-23 μg ml(- 1), respectively, according to the examined species. epidermophyton floccosum was the most sensitive fungus to agnps, while trichophyt ... | 2015 | 26296782 |
| use of restriction fragment length polymorphism to rapidly identify dermatophyte species related to dermatophytosis. | dermatophytes are a group of keratinophilic fungi worldwide, which can infect the skin, hair and nails of humans and animals. this genus includes several species that present different features of dermatophytosis. although, laboratory diagnosis of dermatophytes is based on direct microscopy, biochemical tests and culture, these manners are expensive, time consuming and need skilled staff. therefore, molecular methods like pcr-rflp are the beneficial tools for identification, which are rapid and ... | 2015 | 26301058 |
| dermatoscopic findings as a complementary tool in the differential diagnosis of the etiological agent of tinea capitis. | tinea capitis is a scalp infection caused by fungi. in brazil, the main causative agents are microsporum canis and the trichophyton tonsurans. etiological diagnosis is based on suggestive clinical findings and confirmation depends on the fungus growth in culture. however, it is not always possible to perform this test due to lack of availability. we reveal the dermoscopic findings that enable distinction between the main causative agents of tinea capitis, m. canis and t. tonsurans. the associati ... | 2015 | 26312662 |
| dermatophytosis: a 16-year retrospective study in a metropolitan area in southern brazil. | dermatophytoses are considered a public health problem. the objectives of this study were to determine the evolution of their prevalence in the metropolitan area of porto alegre, brazil, and to analyze the dermatophyte species distribution according to body site and demographic characteristics of the patients. | 2015 | 26322879 |
| evaluation of two molecular techniques for rapid detection of the main dermatophytic agents of tinea capitis. | tinea capitis is very common in western china, with the most widespread aetiological agent being trichophyton violaceum, while microsporum canis is prevalent in the remainder of china. conventional diagnostics and internal transcribed spacer (its) sequencing analyses have proven relatively limited due to the close phylogenetic relationship of anthropophilic dermatophytes. therefore, alternative molecular tools with sufficient specificity, reproducibility and sensitivity are necessary. | 2015 | 26342174 |
| molecular characterization and in vitro antifungal susceptibility of 316 clinical isolates of dermatophytes in iran. | dermatophytosis is a common mycotic infection of the skin, nail, and hair, associated with major public health concern worldwide. various species of dermatophytes show significant differences in susceptibility to antifungals. here, we present the antifungal susceptibility of a large collection of molecularly identified dermatophyte isolates obtained from tropical region of south of iran. a total of 9485 patients clinically suspected to have cutaneous fungal infections were examined. dermatophyto ... | 2016 | 26369643 |
| detection of common dermatophytes in clinical specimens using a simple quantitative real-time taqman polymerase chain reaction assay. | dermatophytes are common fungal pathogens causing mostly superficial infections in humans with a high prevalence worldwide. traditional detection techniques are time-consuming and insensitive, whereas molecular detection methods have proved to be much more rapid and sensitive. | 2016 | 26406273 |
| report: antibacterial and antifungal activities of leaf extract of achyranthes aspera (amaranthaceae) from pakistan. | alcoholic extract and various fractions of achyranthes aspera leaves, traditionally used in pakistan for treatment of infectious diseases was screened for in vitro antibacterial and antifungal activity. the chloroform and butanol fractions were found to be the most active among the fractions, showing considerable antibacterial activity against shigella flexneri and escherichia coli. the highest activity was found in the ethylacetate fraction (17 mm zone of inhibition) against gram-negative (salm ... | 2015 | 26408900 |
| antifungal potential of essential oil and ethanol extracts of lonicera japonica thunb. against dermatophytes. | the antifungal potential of essential oil and ethanolic leaf extracts of lonicera japonica thunb. was evaluated for controlling the growth of dermatophytes. the oil (1,000 ppm) and extracts (1,500 ppm) of l. japonica revealed 55.1-70.3 % and 40.1-65.5 % antidermatophytic effect against microsporum canis kctc 6348, 6349, 6591, trichophyton rubrum kctc 6345, 6352, 6375, trichophyton mentagrophytes kctc 6077 and 6085, respectively, along with their respective minimum inhibitory concentrations rangi ... | 2014 | 26417269 |
| the anti-dermatophyte activity of commiphora molmol. | commiphora molmol engl (burseraceae) or myrrh has been traditionally used for the treatment of skin fungal infections. | 2016 | 26427766 |
| in vitro activity of twenty commercially available, plant-derived essential oils against selected dermatophyte species. | the in vitro activity of twenty chemically defined essential oils (eos) obtained from boswellia sacra, citrus bergamia, c. limon, c. medica, cinnamomum zeylanicum, eucalyptus globulus, foeniculum vulgare, helichrysum italicum, illicium verum, litsea cubeba, mentha spicata, myrtus communis, ocimum basilicum, origanum majorana, o. vulgare, pelargonium graveolens, rosmarinus officinalis, santalum album, satureja montana, and thymus serpyllum was assayed against clinical animal isolates of microspor ... | 2015 | 26434145 |
| [microsporum canis: current data on the prevalence of the zoophilic dermatophyte in central germany]. | microsporum (m.) canis, whose source of infection is mostly cats, is still considered as the most frequently occurring zoophilic dermatophyte in germany and europe. in distinct areas of germany, the zoophilic dermatophyte trichophyton (t.) anamorph of arthroderma (a.) benhamiae also presents a frequent and emerging causative agent of dermatophytoses. | 2015 | 26446665 |
| administration of oral itraconazole capsule with whole milk shows enhanced efficacy as supported by scanning electron microscopy in a child with tinea capitis due to microsporum canis. | although diagnosis and treatment of tinea capitis in children are not difficult, treatment failures are still somewhat common. we report a case of pediatric tinea capitis cured using oral itraconazole administered with whole milk, after prior treatment failure when oral itraconazole was administered with water. this apparent enhanced efficacy in one individual was demonstrated using scanning electron microscopy. | 2015 | 26447934 |
| species identification of dermatophytes in paraffin-embedded biopsies with a new polymerase chain reaction assay targeting the internal transcribed spacer 2 region and comparison with histopathological features. | dermatophytosis is a very common skin infection with a broad clinical spectrum. biopsies are often used to confirm the diagnosis, especially when the clinical presentation is unusual. not uncommonly, organisms are hard to find even with periodic acid-schiff stains. polymerase chain reaction (pcr) for dermatophytes can be used in such cases. | 2016 | 26556042 |
| advances in microbiology, infectious diseases and public health: fungal occurrence in the hair and skin of symptomatic pets in turin, italy. | companion animals, often asymptomatic reservoir of fungi, can be important sources of infection in humans, due to the close contact with their owners. the present study was aimed to assess the occurrence of dermatophytes and other fungi isolated from pet dermatological lesions in turin, italy. dermatological specimens were examined for fungal elements by direct microscopy and cultured to detect dermatophytes, other filamentous fungi and yeasts: 247 pets (118 cats, 111 dogs and 18 dwarf rabbits) ... | 2016 | 26563306 |
| essential oil of algerian eucalyptus citriodora: chemical composition, antifungal activity. | essential oil of eucalyptus citriodora is a natural product which has been attributed for various medicinal uses. in the present investigation, e. citriodora essential oil was used to evaluate its antifungal effect against medically important dermatophytes. | 2015 | 26597375 |
| [2011 epidemiological survey of dermatomycoses in japan]. | an epidemiological survey of dermatomycoses and their causative fungus flora in japan for 2011 was conducted in accordance with methods and criteria of the past four surveys. the survey covered a total number of 36,052 outpatients who visited 12 dermatological clinics throughout japan. the results were as follows. 1）dermatophytosis was the most prevalent cutaneous fungal infection (2,980 cases) seen in these clinics, followed by candidiasis (378 cases) and then malassezia infections (152 cases). ... | 2015 | 26617109 |
| tinea corporis, caused by microsporum canis - a case report from kosovo. | tinea corporis (b35.6) caused by microsporum canis which is fungal species that causes numerous forms of disease. it is part of a group of fungi known as dermatophytes. though mostly well known for ringworm in pets, it is also known to infect humans. this fact makes this pathogen both anthrophilic and zoophilic in nature. microsporum canis is a communicable pathogen. | 2015 | 26622092 |
| [a recurrent case of adult favus successfully treated with terbinafine]. | favus or tinea capitis favosa, is a chronic inflammatory dermatophytosis of the scalp. the disease is particularly common in children aged 6 to 10 years, more often in boys, and it also occurs in adults. human-to-human transmission is therefore possible. anthropophilic trichophyton schöenleinii is responsible for over 95% of favus cases. in addition, there are rare cases of anthropophilic t.violaceum, zoophilic (t.verrucosum, t.quinckeanum, and microsporum canis) and geophilic m.gypseum species ... | 2015 | 26649420 |
| increased circulating th17 cell in a patient with tinea capitis caused by microsporum canis. | 2016 | 26666478 | |
| antiproliferative effect and characterization of a novel antifungal peptide derived from human chromogranin a. | cga-n46 is a novel antifungal peptide derived from the n-terminus of human chromogranin a, corresponding to the 31st to 76th amino acids. further research on its activities and characteristics may be helpful for the application of cga-n46 in medical or other situations. in the present study, the antifungal spectrum and physicochemical characteristics of cga-n46 were investigated using an antifungal assay, its antiproliferative effects on cancer and normal cells were assessed using mtt assay and ... | 2015 | 26668630 |
| chemical composition and antifungal activity of essential oil from eucalyptus smithii against dermatophytes. | in this study, we evaluated the chemical composition of a commercial sample of essential oil from eucalyptus smithii r.t. baker and its antifungal activity against microsporum canis atcc 32903, microsporum gypseum atcc 14683, trichophyton mentagrophytes atcc 9533, t. mentagrophytes atcc 11480, t. mentagrophytes atcc 11481, and trichophyton rubrum cct 5507. | 2015 | 26676500 |
| [tinea capitis in the military hospital avicenna (morocco): review of 8 years (2006-2013)]. | tinea capitis are due to fungal infection by dermatophytes. they are common in developing countries including morocco. the objective of this study intended to describe the epidemiology, clinical and mycological profile of tinea capitis in avicenna military hospital of marrakech. | 2016 | 26778722 |
| an open-field study comparing an essential oil-based shampoo with miconazole/chlorhexidine for hair coat disinfection in cats with spontaneous microsporiasis. | the goal of the present study was to compare the antifungal efficacy of an essential oil (eo) shampoo proven to be effective against microsporum canis with miconazole/chlorhexidine for topical hair coat disinfection in cats treated concurrently with oral itraconazole. | 2016 | 26783019 |
| ailanthus altissima (miller) swingle fruit - new acyl β-sitosteryl glucoside and in vitro pharmacological evaluation. | β-sitosterol-3-o-(6'-o-13"-octadecenoyl)-β-d-glucoside (1), a new acyl β-sitosteryl glucoside, along with three known compounds β-sitosterol-3-o-β-d-glucoside (2), β-sitosterol (3) and methyl gallate (4) have been isolated from the ethyl acetate soluble fraction of methanolic extract of ailanthus altissima fruits. their structures were elucidated through spectroscopic data including 2d nmr, esi-ms, methanolysis and oxidative cleavage of double bond. antibacterial, antifungal, cytotoxic, phytotox ... | 2016 | 26795253 |
| synthesis, biological evaluation and molecular docking of certain sulfones as potential nonazole antifungal agents. | we reported herein the synthesis, antifungal activity, docking and in silico adme prediction studies of four novel series of sulfones 6a-f, 8a-c, 10a-f and 12a-c. all the newly synthesized sulfones were tested against four strains of candida (including fluconazole-resistant candida), two strains of aspergillus, two dermatophytic fungi (trichophytons mentagrophyte and microsporum canis) and syncephalastrum sp. with fluconazole as a reference drug. in general, compounds 8a and 10b showed selective ... | 2016 | 26805791 |
| in vitro efficacy of shampoos containing miconazole, ketoconazole, climbazole or accelerated hydrogen peroxide against microsporum canis and trichophyton species. | objectives the objective was to evaluate the antifungal efficacy of shampoo formulations of ketoconazole, miconazole or climbazole and accelerated hydrogen peroxide wash/rinse against microsporum canis and trichophyton species spores. methods lime sulfur (1:16)-treated control, enilconazole (1:100)-treated control, accelerated hydrogen peroxide (ahp 7%) 1:20 and a 1:10 dilution of shampoo formulations of miconazole 2%, miconazole 2%/chlorhexidine gluconate 2-2.3%, ketoconazole 1%/chlorhexidine 2 ... | 2017 | 26809882 |
| determining the pathogenic potential of non-sporulating molds isolated from cutaneous specimens. | although non-sporulating molds (nsm) are frequently isolated from patients and have been recognized as agents of pulmonary disease, their clinical significance in cutaneous specimens is relatively unknown. therefore, this study aimed to identify nsm and to determine the keratinolytic activity of isolates from cutaneous sites. nsm isolates from clinical specimens such as skin, nail, and body fluids were identified based on their ribosomal dna sequences. of 17 nsm isolates (7 ascomycota, 10 basidi ... | 2016 | 26847667 |
| synthesis and evaluation of thiophene-based guanylhydrazones (iminoguanidines) efficient against panel of voriconazole-resistant fungal isolates. | a series of new thiophene-based guanylhydrazones (iminoguanidines) were synthesized in high yields using a straightforward two-step procedure. the antifungal activity of compounds was evaluated against a wide range of medicaly important fungal strains including yeasts, molds, and dermatophytes in comparison to clinically used drug voriconazole. cytotoxic properties of compounds were also determined using human lung fibroblast cell line and hemolysis assay. all guanylhydrazones showed significant ... | 2016 | 26867487 |
| phylogenetic analysis of dermatophyte species using dna sequence polymorphism in calmodulin gene. | use of phylogenetic species concepts based on rdna internal transcribe spacer (its) regions have improved the taxonomy of dermatophyte species; however, confirmation and refinement using other genes are needed. since the calmodulin gene has not been systematically used in dermatophyte taxonomy, we evaluated its intra- and interspecies sequence variation as well as its application in identification, phylogenetic analysis, and taxonomy of 202 strains of 29 dermatophyte species. a set of primers wa ... | 2016 | 26868901 |
| epidemiology of superficial fungal infections in guangdong, southern china: a retrospective study from 2004 to 2014. | superficial fungal infections are common worldwide; however, the distribution of pathogenic species varies among geographical areas and changes over time. this study aimed to determine the epidemiologic profile of superficial fungal infections during 2004-2014 in guangzhou, southern china. data regarding the superficial mycoses from outpatients and inpatients in our hospital were recorded and analyzed. from the 3367 patients that were enrolled in the study, 3385 samples were collected from skin, ... | 2016 | 26883512 |
| epidemiological aspects of dermatophytosis in khuzestan, southwestern iran, an update. | dermatophytosis is among the most common superficial mycoses in iran. the purpose of this report was to update the clinical and mycological features of human dermatophytosis in the khuzestan, southwestern iran. in the framework of a one-year survey, a total of 4120 skin, hair and nail samples obtained from the outpatients with symptoms suggestive of tinea were analyzed by using direct microscopy, culture and molecular identification methods. strains isolated from cultures were subjected to ampli ... | 2016 | 26886443 |
| tinea faciei caused by trichophyton mentagrophytes in a 20-day-old neonate. | although candidiasis in newborns is not uncommon, superficial dermatophyte infections of infants is quite rare. the causative agents of neonatal tinea reported in various case studies have been trichophyton rubrum, microsporum canis, microsporum gypseum, and trichophyton violaceum. to the best of our knowledge, no case report of neonatal tinea faciei caused by trichophyton mentagrophytes has been reported earlier. | 2015 | 26904450 |
| overexpression of tlr-2 and tlr-4 mrna in feline polymorphonuclear neutrophils exposed to microsporum canis. | polymorphonuclear neutrophils (pmns), along with macrophages, are the first leukocytes recruited to the site of infection in dermatophytoses and are responsible for the in fine elimination of the fungus. it has been demonstrated that feline pmns produce pro-inflammatory cytokines after stimulation with microsporum canis. the activation of these cells results from the recognition of specific pamps (pathogen associated molecular patterns) from m. canis by prrs (pattern recognition receptors) of pm ... | 2016 | 26914839 |
| decontamination of carpet exposed to microsporum canis hairs and spores. | objectives the objective of this study was to evaluate the efficacy of vacuuming and three carpet cleaning methods for the removal of microsporum canis spores and hairs from experimentally contaminated carpets. methods sterile berber carpeting was artificially contaminated with naturally infective m canis hairs and spores. carpet swatches were vacuumed for 10 s, 30 s and 60 s, and then cultured. three carpet cleaning methods were evaluated on area rugs experimentally contaminated with infective ... | 2017 | 26927817 |
| antifungal, antiradical and cytotoxic activities of extractives obtained from tagetes patula l. (asteraceae), a potential acaricide plant species. | tagetes patula l. shows a complex chemical composition, ranging from glycosylated flavonoids and thiophenes in extracts until terpenoids in the essential oil. in the present study, due to this rich flavonoidic constitution, its antioxidant potential was determined, having shown values of antiradical percentage superior to reference compounds, mainly the extracts prepared with flowers. previous studies performed emphasized the acaricide potential of t. patula and thus, the present study aimed to ... | 2016 | 26945559 |
| detection and characterization of zoonotic dermatophytes from dogs and cats in and around kolkata. | the ringworms of pet dogs, cats, and stray animals (dogs, cats, and other animals) could be a potential source of zoonotic infections causing a serious public health problem in the busy city kolkata. the pet owners are more susceptible to get this infection from their pets, because of the close contact with them as dermatophytosis is very much prevalent in those pets. so, this study was aimed to check the prevalence of dermatophytosis in dogs, cats, and in pet owners. | 2015 | 27047202 |
| antifungal activity of cymbopogon nardus (l.) rendle (citronella) against microsporum canis from animals and home environment. | dermatophytosis is a common zoonosis in urban centers. dogs and cats have played an important role as its disseminators. environmental decontamination is essential for the prevention of its propagation to humans and animals. however, sanitizers or disinfectants with antifungal activity, currently available, have high toxicity. the present study evaluated the in vitro effects of an extract of citronella (cymbopogon nardus) on 31 microsporum canis isolates from animals and home environments. susce ... | 2015 | 27049705 |
| invasive microsporum canis causing rhinitis and stomatitis in a cat. | microsporum canis is a pathogenic fungus that typically causes dermatophytosis in cats. this report describes a cat with a microsporum canis infection causing invasive fungal rhinitis that extended through the hard palate, resulting in adjacent stomatitis. treatment with itraconazole and terbinafine resolved the infection. | 2016 | 27061928 |
| antimicrobial activity of synthesized 2-methylthiobenzo[g][1,2,4]- triazolo[1,5-a]quinazoline derivatives. | the present study was carried out to evaluate the antimicrobial activity of a synthesized 2-methylthio-benzo[g][1,2,4]triazolo[1,5- a]quinazoline series. the compounds (1-21) were tested against a variety of gram-positive bacterial species including bacillus subtilis (rcmb 01001 69-3), enterococcus faecalis (rcmb 0100154-2), staphylococcus aureus (rcmb 0100183-9), staphylococcus epidermidis (rcmb 0100183-9) and streptococcus pyogenes (rcmb 0100172-5). in addition, gram-negative bacteria were als ... | 2016 | 27140181 |
| an epidemiological study of animals dermatomycoses in iran. | to determine the fungal species isolated from skin lesions of different animals suspected of having dermatomycoses and their prevalence in different regions of iran. | 2016 | 27180290 |
| anti-fungal potential of ozone against some dermatophytes. | dermatophytes are classified in three genera, epidermophyton, microsporum and trichophyton. they have the capacity to invade keratinized tissue to produce a cutaneous infection known as dermatophytoses. this investigation was performed to study the effect of gaseous ozone and ozonized oil on three specific properties of six different dermatophytes. these properties included sporulation, mycelia leakage of sugar and nutrients and the activity of their hydrolytic enzymes. generally, ozonized oil w ... | 2017 | 27287337 |
| lenghty reverse poly(butylene oxide)-poly(ethylene oxide)-poly(butylene oxide) polymeric micelles and gels for sustained release of antifungal drugs. | in this work, we present a detailed study of the potential application of polymeric micelles and gels of four different reverse triblock poly(butylene oxide)-poly(ethylene oxide)-poly(butylene oxide) copolymers (boneombon, where n denotes the respective block lengths), specifically bo8eo90bo8, bo14eo378bo14, bo20eo411bo20 and bo21eo385bo21, as effective drug transport nanocarriers. in particular, we tested the use of this kind of polymeric nanostructures as reservoirs for the sustained delivery ... | 2016 | 27289012 |
| in vitro evaluation of antifungal susceptibility and keratinase, elastase, lipase and dnase activities of different dermatophyte species isolated from clinical specimens in iran. | the aims of this study were to evaluate the enzymatic activity of various dermatophyte species and their antifungal susceptibility profiles. a total of 60 dermatophyte isolates, including trichophyton mentagrophytes, trichophyton rubrum, microsporum canis and microsporum gypseum, were examined. fungal isolates were analysed for the production of keratinase, lipase, elastase and deoxyribonuclease (dnase). a broth microdilution method was performed on the basis of m38-a2 clinical and laboratory st ... | 2016 | 27291045 |
| pcr and real-time pcr approaches to the identification of arthroderma otae species microsporum canis and microsporum audouinii/microsporum ferrugineum. | the identification of species in the arthroderma otae complex is essential to determine the origin of infection and to eliminate the risk of transmission. microsporum canis is a zoophilic species, whereas microsporum audouinii and microsporum ferrugineum are anthropophilic species. in this paper, we propose alternative methods that permit species-specific identification of both anthropophilic and zoophilic members of the a. otae complex methods: two pcr assays were designed based on differences ... | 2016 | 27306227 |
| antimicrobial activity of new 2-thioxo-benzo[g]quinazolin-4(3h)-one derivatives. | the antimicrobial activity of a synthesized series of 28 2-thioxo-benzo[g]quinazolin-4(3h)-one derivatives was evaluated in vitro against five gram-positive bacteria, including bacillus subtilis, enterococcus faecalis, staphylococcus aureus, staphylococcus epidermidis and streptococcus pyogenes. the antibacterial activity was extended to include five gram-negative bacteria: pseudomonas aeruginosa, escherichia coli, proteus mirabilis, klebsiella oxytoca and enterobacter cloacae. furthermore, the ... | 2016 | 27306606 |