Publications

TitleAbstractYear
Filter
PMID(sorted ascending)
Filter
incidence of keratinophilic fungi from the soils of vedanthangal water bird sanctuary (india).summary fifty-three soil samples were collected from various sites in the vicinity of vedanthangal water bird sanctuary and screened for the presence of keratinophilic fungi using the hair baiting techniques for isolation. twenty-eight isolates were recovered and identified by recognition of their macro- and micromorphological features. seven species related to five genera were recorded viz. auxarthron conjugatum (1.89%), chrysosporium fluviale (3.77%), chrysosporium indicum (20.75%), chrysospor ...201020406397
antifungal activity of dodonaea viscosa jacq extract on pathogenic fungi isolated from superficial skin infection.antimicrobial activity of solvent extracts of leaves and shoot of dodonaea viscosa jacq have been determined against fungi, aspergillus niger, aspergillus flavus, paecilomyces varioti, microsporum gypseum, and trichophyton rubrum causing skin diseases. all crude extracts were found to be effective against tested fungi. however chloroform has strong inhibition activity against fungi as compared to ethanol, methanol, ethylacetate and aqueous extracts. more over in present study some basic elements ...201020566450
antifungal activity of dodonaea viscosa jacq extract on pathogenic fungi isolated from superficial skin infection.antimicrobial activity of solvent extracts of leaves and shoot of dodonaea viscosa jacq have been determined against fungi, aspergillus niger, aspergillus flavus, paecilomyces varioti, microsporum gypseum, and trichophyton rubrum causing skin diseases. all crude extracts were found to be effective against tested fungi. however chloroform has strong inhibition activity against fungi as compared to ethanol, methanol, ethylacetate and aqueous extracts. more over in present study some basic elements ...201020566450
identification and characterisation of human pathogenic filamentous fungi and susceptibility to thymus schimperi essential oil.summary twenty-eight clinical fungal isolates were characterised by morphological (macro- and micro-features and growth response at 25, 30 and 37 degrees c) and molecular (nuclear rdna-internal transcriber spacer, calmodulin, cytochrome c oxidase 1 and the largest subunit of rna polymerase ii) analyses. the clinical fungal isolates were ascribed to the following taxa: penicillium chrysogenum, verticillium sp., aspergillus tubingensis, aspergillus minutus, beauveria bassiana and microsporum gypse ...201020633233
identification and characterisation of human pathogenic filamentous fungi and susceptibility to thymus schimperi essential oil.summary twenty-eight clinical fungal isolates were characterised by morphological (macro- and micro-features and growth response at 25, 30 and 37 degrees c) and molecular (nuclear rdna-internal transcriber spacer, calmodulin, cytochrome c oxidase 1 and the largest subunit of rna polymerase ii) analyses. the clinical fungal isolates were ascribed to the following taxa: penicillium chrysogenum, verticillium sp., aspergillus tubingensis, aspergillus minutus, beauveria bassiana and microsporum gypse ...201020633233
antifungal activity of extracts and prenylated coumarins isolated from baccharis darwinii hook & arn. (asteraceae).the petroleum ether extract of baccharis darwinii showed activity against cryptococcus neoformans and dermatophytes. bioactivity-guided fractionation of baccharis darwinii has resulted in the isolation of three coumarins: 5'-hydroxy aurapten (anisocoumarin h, 1), aurapten (7-geranyloxycoumarin, 2) and 5'-oxoaurapten (diversinin, 3). the structures of these compounds were characterized by spectroscopic methods. these compounds were evaluated for their antimicrobialactivity against a panel of each ...201020657398
antifungal activity of extracts and prenylated coumarins isolated from baccharis darwinii hook & arn. (asteraceae).the petroleum ether extract of baccharis darwinii showed activity against cryptococcus neoformans and dermatophytes. bioactivity-guided fractionation of baccharis darwinii has resulted in the isolation of three coumarins: 5'-hydroxy aurapten (anisocoumarin h, 1), aurapten (7-geranyloxycoumarin, 2) and 5'-oxoaurapten (diversinin, 3). the structures of these compounds were characterized by spectroscopic methods. these compounds were evaluated for their antimicrobialactivity against a panel of each ...201020657398
a case of kerion celsi caused by microsporum gypseum in a boy following dermatoplasty for a scalp wound from a road accident.we report a rare case of kerion celsi of the scalp caused by microsporum gypseum in a boy 1 month after he received dermatoplasty for a scalp injury from a road accident. species identification was performed by observation of morphologic and biochemical characteristics and sequencing of the internal transcribed spacers (its) 1 and 2. treatment with oral terbinafine and topical naftifine-ketoconazole cream after washing the hair with ketoconazole shampoo was effective.201120662636
a case of kerion celsi caused by microsporum gypseum in a boy following dermatoplasty for a scalp wound from a road accident.we report a rare case of kerion celsi of the scalp caused by microsporum gypseum in a boy 1 month after he received dermatoplasty for a scalp injury from a road accident. species identification was performed by observation of morphologic and biochemical characteristics and sequencing of the internal transcribed spacers (its) 1 and 2. treatment with oral terbinafine and topical naftifine-ketoconazole cream after washing the hair with ketoconazole shampoo was effective.201120662636
dermatophytes in republic of macedonia.(full text is available at http://www.manu.edu.mk/prilozi). a total of 1742 clinically suspected samples was examined for the incidence and distribution of dermatophytes in the republic of macedonia from june 2007 to jan. 2009. 600 dermatophytes were isolated and identified. in the studied period 9 different dermatophyte species were isolated, namely trichophyton rubrum (48.83%), microsporum canis (20%), trichophyton mentagrophytes var. interdigitale (16.83%), epidermophyton floccosum (4.17%), t ...201020693949
dermatophytes in republic of macedonia.(full text is available at http://www.manu.edu.mk/prilozi). a total of 1742 clinically suspected samples was examined for the incidence and distribution of dermatophytes in the republic of macedonia from june 2007 to jan. 2009. 600 dermatophytes were isolated and identified. in the studied period 9 different dermatophyte species were isolated, namely trichophyton rubrum (48.83%), microsporum canis (20%), trichophyton mentagrophytes var. interdigitale (16.83%), epidermophyton floccosum (4.17%), t ...201020693949
strange formation of n-hydroxy-3,3-dimethyl-2,6-diarylpiperidin-4-one and its oxime derivative--synthesis, stereochemistry, antibacterial and antifungal activity.objectives and methods: a collection of novel n-hydroxy-3,3-dimethyl-2,6-diarylpiperidin-4-one oximes 28-32 are synthesized, characterized by melting point, elemental analysis, ms, ft-ir, one-dimensional nmr (1h & 13c) and two dimensional noesy spectroscopic data and evaluate for their in vitro antibacterial and antifungal activities. results and conclusion: compound 32, exerted a wide range of antibacterial activities against the entire tested gram-positive and gram-negative bacterial strains e ...201020707249
strange formation of n-hydroxy-3,3-dimethyl-2,6-diarylpiperidin-4-one and its oxime derivative--synthesis, stereochemistry, antibacterial and antifungal activity.objectives and methods: a collection of novel n-hydroxy-3,3-dimethyl-2,6-diarylpiperidin-4-one oximes 28-32 are synthesized, characterized by melting point, elemental analysis, ms, ft-ir, one-dimensional nmr (1h & 13c) and two dimensional noesy spectroscopic data and evaluate for their in vitro antibacterial and antifungal activities. results and conclusion: compound 32, exerted a wide range of antibacterial activities against the entire tested gram-positive and gram-negative bacterial strains e ...201020707249
keratinolytic fungi in sewage sludge.sewage sludge from the upper silesia region of poland were surveyed for keratinolytic fungi. out of 100 petri dishes examined, 89 were positive for these micro-organisms. altogether, 185 fungal appearances belonging to 10 species were observed. trichophyton terrestre with its teleomorph arthroderma quadrifidum, t. ajelloi with a. uncinatum, microsporum gypseum with arthroderma sp., and chrysosporium keratinophilum with aphanoascus keratinophilus prevailed in the sludges. the sewage treatment tec ...199620882456
keratinolytic fungi in sewage sludge.sewage sludge from the upper silesia region of poland were surveyed for keratinolytic fungi. out of 100 petri dishes examined, 89 were positive for these micro-organisms. altogether, 185 fungal appearances belonging to 10 species were observed. trichophyton terrestre with its teleomorph arthroderma quadrifidum, t. ajelloi with a. uncinatum, microsporum gypseum with arthroderma sp., and chrysosporium keratinophilum with aphanoascus keratinophilus prevailed in the sludges. the sewage treatment tec ...199620882456
superficial fungal infections seen at a tertiary health centre: clinical and mycological studies.superficial fungal infections are common in the tropics, partly due to the climate, relatively poor hygiene, and lifestyle of the people.201020931516
superficial fungal infections seen at a tertiary health centre: clinical and mycological studies.superficial fungal infections are common in the tropics, partly due to the climate, relatively poor hygiene, and lifestyle of the people.201020931516
extracellular protease expression in microsporum gypseum complex, its regulation and keratinolytic potential.two soil isolates of microsporum gypseum were studied for the production of extracellular proteases. both the strains secreted protease on glucose-gelatin medium. the enzyme activity peaked on day 15 at 28 °c. asparagine repressed protease yield. sugars caused catabolite repression of protease formation. protease activities of both the isolates were significantly affected by incubation period, culture media and carbohydrates used. both the strains grew on the skin bait and caused a gravimetrical ...201020946260
extracellular protease expression in microsporum gypseum complex, its regulation and keratinolytic potential.two soil isolates of microsporum gypseum were studied for the production of extracellular proteases. both the strains secreted protease on glucose-gelatin medium. the enzyme activity peaked on day 15 at 28 °c. asparagine repressed protease yield. sugars caused catabolite repression of protease formation. protease activities of both the isolates were significantly affected by incubation period, culture media and carbohydrates used. both the strains grew on the skin bait and caused a gravimetrical ...201020946260
clinicomicrobiological aspects of tinea cruris in madras.a total of 242 patients with clinically diagnosed tinea cruris were screened and 181 (74.7 %) were found to be positive in culture for dermatophytes. 93.9% of infections were caused by trichophyton spp., of which 58.4% were trichophyton rubrum, 5.5% were epidermophyton floccosum, 3.8% were trichophyton tonsurans and we had a single isolate of microsporum gypseum complex. incidence of tinea cruris was higher in males (95.6%) than in females (4.4%). 45% of the cases were recurrent and 38% of cases ...199620948056
clinicomicrobiological aspects of tinea cruris in madras.a total of 242 patients with clinically diagnosed tinea cruris were screened and 181 (74.7 %) were found to be positive in culture for dermatophytes. 93.9% of infections were caused by trichophyton spp., of which 58.4% were trichophyton rubrum, 5.5% were epidermophyton floccosum, 3.8% were trichophyton tonsurans and we had a single isolate of microsporum gypseum complex. incidence of tinea cruris was higher in males (95.6%) than in females (4.4%). 45% of the cases were recurrent and 38% of cases ...199620948056
chemical composition and biological assays of essential oils of calamintha nepeta (l.) savi subsp. nepeta (lamiaceae).aerial parts of wild calamintha nepeta (l.) savi subsp. nepeta growing spontaneously on the mediterranean coast (sardinia island, italy) and on the atlantic coast (portugal) were used as a matrix for the supercritical extraction of volatile oil with co(2). the collected extracts were analysed by gc-fid and gc-ms methods and their compositions were compared with that of the essential oil isolated by hydrodistillation, but the differences were not relevant. a strong chemical variability was observ ...201020981614
chemical composition and biological assays of essential oils of calamintha nepeta (l.) savi subsp. nepeta (lamiaceae).aerial parts of wild calamintha nepeta (l.) savi subsp. nepeta growing spontaneously on the mediterranean coast (sardinia island, italy) and on the atlantic coast (portugal) were used as a matrix for the supercritical extraction of volatile oil with co(2). the collected extracts were analysed by gc-fid and gc-ms methods and their compositions were compared with that of the essential oil isolated by hydrodistillation, but the differences were not relevant. a strong chemical variability was observ ...201020981614
effects of temperature variations and light exposure on the time to growth of dermatophytes using six different fungal culture media inoculated with laboratory strains and samples obtained from infected cats.in this study, 5/6 commercially available fungal culture media were comparable with respect to first growth, first colour change, and first sporulation when inoculated with three strains of microsporum canis, one strain of microsporum gypseum, and one strain of trichophyton species when incubated at either 25°c or 30°c. five of six plates showed 100% growth at both temperatures. five of six plates showed 100% growth when inoculated with naturally infective m canis hairs and spores. one commercia ...201021051255
effects of temperature variations and light exposure on the time to growth of dermatophytes using six different fungal culture media inoculated with laboratory strains and samples obtained from infected cats.in this study, 5/6 commercially available fungal culture media were comparable with respect to first growth, first colour change, and first sporulation when inoculated with three strains of microsporum canis, one strain of microsporum gypseum, and one strain of trichophyton species when incubated at either 25°c or 30°c. five of six plates showed 100% growth at both temperatures. five of six plates showed 100% growth when inoculated with naturally infective m canis hairs and spores. one commercia ...201021051255
sequenced dermatophyte strains: growth rate, conidiation, drug susceptibilities, and virulence in an invertebrate model.although dermatophytes are the most common cause of fungal infections in the world, their basic biology is not well understood. the recent sequencing and annotation of the genomes of five representative dermatophyte species allows for the creation of hypotheses as to how they cause disease and have adapted to their distinct environments. an understanding of the microbiology of these strains will be essential for testing these hypotheses. this study is the first to generally characterize these fi ...201021145410
sequenced dermatophyte strains: growth rate, conidiation, drug susceptibilities, and virulence in an invertebrate model.although dermatophytes are the most common cause of fungal infections in the world, their basic biology is not well understood. the recent sequencing and annotation of the genomes of five representative dermatophyte species allows for the creation of hypotheses as to how they cause disease and have adapted to their distinct environments. an understanding of the microbiology of these strains will be essential for testing these hypotheses. this study is the first to generally characterize these fi ...201021145410
synthesis and in vitro microbiological evaluation of novel diethyl 6,6'-(1,4-phenylene)bis(4-aryl-2-oxo-cyclohex-3-enecarboxylates).novel bis cyclohexenone ester derivatives 14-19 were synthesized and characterized by their spectral data. in vitro microbiological evaluations were carried out for all the novel compounds 14-19 against clinically isolated bacterial and fungal strains. compounds 15, 16, 18 against staphylococcus aureus, 14, 15 against ß-haemolytic streptococcus, 15, 19 against micrococcus luteus, 17, 18 against salmonella typhii, 14, 17 against shigella flexneri, 15 against escherichia coli, 16 against pseudomon ...201121417963
synthesis and in vitro microbiological evaluation of novel diethyl 6,6'-(1,4-phenylene)bis(4-aryl-2-oxo-cyclohex-3-enecarboxylates).novel bis cyclohexenone ester derivatives 14-19 were synthesized and characterized by their spectral data. in vitro microbiological evaluations were carried out for all the novel compounds 14-19 against clinically isolated bacterial and fungal strains. compounds 15, 16, 18 against staphylococcus aureus, 14, 15 against ß-haemolytic streptococcus, 15, 19 against micrococcus luteus, 17, 18 against salmonella typhii, 14, 17 against shigella flexneri, 15 against escherichia coli, 16 against pseudomon ...201121417963
tinea incognito caused by microsporum gypseum in a patient with advanced hiv infection: a case report.the prevalence and the clinical relevance of dermatophytoses in hiv-infected patients are poorly documented, particularly for those caused by tinea incognito. here, we report a case of widespread facial tinea incognito occurring in an italian patient with advanced hiv infection, showing both skin and brain lesions. second-line treatment with liposomal amphotericin b and cotrimoxazole, administered after a microbiological characterization of the skin scrapings, led to complete clearance of all le ...201121487462
tinea incognito caused by microsporum gypseum in a patient with advanced hiv infection: a case report.the prevalence and the clinical relevance of dermatophytoses in hiv-infected patients are poorly documented, particularly for those caused by tinea incognito. here, we report a case of widespread facial tinea incognito occurring in an italian patient with advanced hiv infection, showing both skin and brain lesions. second-line treatment with liposomal amphotericin b and cotrimoxazole, administered after a microbiological characterization of the skin scrapings, led to complete clearance of all le ...201121487462
essential oils of medicinal plants from the central andes of argentina: chemical composition, and antifungal, antibacterial, and insect-repellent activities.the antifungal, antibacterial, and insect-repellent activities of the essential oils (eos) of acantholippia seriphioides, artemisia mendozana, gymnophyton polycephalum, satureja parvifolia, tagetes mendocina, and lippia integrifolia, collected in the central andes area, province of san juan, argentina, were investigated. the dermatophytes microsporum gypseum, trichophyton mentagrophytes, and t. rubrum were inhibited by the eos of g. polycephalum, l. integrifolia, and s. parvifolia, with minimum ...201121560241
essential oils of medicinal plants from the central andes of argentina: chemical composition, and antifungal, antibacterial, and insect-repellent activities.the antifungal, antibacterial, and insect-repellent activities of the essential oils (eos) of acantholippia seriphioides, artemisia mendozana, gymnophyton polycephalum, satureja parvifolia, tagetes mendocina, and lippia integrifolia, collected in the central andes area, province of san juan, argentina, were investigated. the dermatophytes microsporum gypseum, trichophyton mentagrophytes, and t. rubrum were inhibited by the eos of g. polycephalum, l. integrifolia, and s. parvifolia, with minimum ...201121560241
melanogenesis in dermatophyte species in vitro and during infection.dermatophytes are keratinophilic fungi that are the most common cause of fungal skin infections worldwide. melanin has been isolated from several important human fungal pathogens and the polymeric pigment is now recognized as an important virulence determinant. this study investigated whether dermatophytes, including trichophyton rubrum, t. mentagrophytes, epidermophyton floccosum, and microsporum gypseum, produce melanin or melanin-like compounds in vitro and during infection. digestion of the ...201121565930
melanogenesis in dermatophyte species in vitro and during infection.dermatophytes are keratinophilic fungi that are the most common cause of fungal skin infections worldwide. melanin has been isolated from several important human fungal pathogens and the polymeric pigment is now recognized as an important virulence determinant. this study investigated whether dermatophytes, including trichophyton rubrum, t. mentagrophytes, epidermophyton floccosum, and microsporum gypseum, produce melanin or melanin-like compounds in vitro and during infection. digestion of the ...201121565930
argentinean andean propolis associated with the medicinal plant larrea nitida cav. (zygophyllaceae). hplc-ms and gc-ms characterization and antifungal activity.the chemical profile and botanical origin of andean argentinian propolis were studied by hplc-esi-ms/ms and gc-ms techniques as well as the antifungal activity according to clsi protocols. dermatophytes and yeasts tested were strongly inhibited by propolis extracts (mics between 31.25 and 125μg/ml). the main antifungal compounds were: 3'methyl-nordihydroguaiaretic acid (mndga) 1, nordihydroguaiaretic acid (ndga) 2 and a ndga derivative 3, showing strong activity against trichophyton mentagrophyt ...201121600954
argentinean andean propolis associated with the medicinal plant larrea nitida cav. (zygophyllaceae). hplc-ms and gc-ms characterization and antifungal activity.the chemical profile and botanical origin of andean argentinian propolis were studied by hplc-esi-ms/ms and gc-ms techniques as well as the antifungal activity according to clsi protocols. dermatophytes and yeasts tested were strongly inhibited by propolis extracts (mics between 31.25 and 125μg/ml). the main antifungal compounds were: 3'methyl-nordihydroguaiaretic acid (mndga) 1, nordihydroguaiaretic acid (ndga) 2 and a ndga derivative 3, showing strong activity against trichophyton mentagrophyt ...201121600954
antidermatophytic activity of pyrazolo[3,4-c]isothiazoles: a preliminary approach on 4-chlorophenyl derivative for evaluation of mutagenic and clastogenic effects on bacteria and human chromosomes in vitro.the antifungal activity of eight pyrazolo[3,4-c]isothiazole derivatives was evaluated on five dermatophytes: three were of an anthropophilic species (i.e., epidermophyton floccosum, trichophyton rubrum, and trichophyton tonsurans) and two were of a geophilic species (i.e., microsporum gypseum and nannizzia cajetani). the new compounds proved to be unlikely effective in inhibiting the growth of the different strains. in general, the fungi parasitic on man were more sensitive than the geophilic sp ...201121649488
antidermatophytic activity of pyrazolo[3,4-c]isothiazoles: a preliminary approach on 4-chlorophenyl derivative for evaluation of mutagenic and clastogenic effects on bacteria and human chromosomes in vitro.the antifungal activity of eight pyrazolo[3,4-c]isothiazole derivatives was evaluated on five dermatophytes: three were of an anthropophilic species (i.e., epidermophyton floccosum, trichophyton rubrum, and trichophyton tonsurans) and two were of a geophilic species (i.e., microsporum gypseum and nannizzia cajetani). the new compounds proved to be unlikely effective in inhibiting the growth of the different strains. in general, the fungi parasitic on man were more sensitive than the geophilic sp ...201121649488
modiolide and pyrone derivatives from the sea fan-derived fungus curvularia sp. psu-f22.investigation of secondary metabolites from the sea fan-derived fungus curvularia sp. psu-f22 resulted in isolation of three new metabolites, curvulapyrone (1), curvulalide (2) and curvulalic acid (3) together with six known compounds, modiolides a (4) and b (5), pyrenolide a (6), stagonolide e (7), mycoepoxydiene (8), and deacetylmycoepoxydiene (9). their antimicrobial activity against staphylococcus aureus atcc 25923, methicillin-resistant s. aureus and microsporum gypseum sh-mu-4 were examine ...201121656354
modiolide and pyrone derivatives from the sea fan-derived fungus curvularia sp. psu-f22.investigation of secondary metabolites from the sea fan-derived fungus curvularia sp. psu-f22 resulted in isolation of three new metabolites, curvulapyrone (1), curvulalide (2) and curvulalic acid (3) together with six known compounds, modiolides a (4) and b (5), pyrenolide a (6), stagonolide e (7), mycoepoxydiene (8), and deacetylmycoepoxydiene (9). their antimicrobial activity against staphylococcus aureus atcc 25923, methicillin-resistant s. aureus and microsporum gypseum sh-mu-4 were examine ...201121656354
Substituted 2-aminothiophenes: antifungal activities and effect on Microsporum gypseum protein profile.The increasing recognition and importance of fungal infections, the difficulties encountered in their treatment and the increase in resistance to antifungal agents have stimulated the search for therapeutic alternatives. The objective of this study was to evaluate the antifungal activities of three substituted 2-aminothiophenes (1, 2 and 3) against some fungal species. The synthesis of substituted 2-aminothiophenes was carried out through the most versatile synthetic method developed by Gewald e ...201121831103
Substituted 2-aminothiophenes: antifungal activities and effect on Microsporum gypseum protein profile.The increasing recognition and importance of fungal infections, the difficulties encountered in their treatment and the increase in resistance to antifungal agents have stimulated the search for therapeutic alternatives. The objective of this study was to evaluate the antifungal activities of three substituted 2-aminothiophenes (1, 2 and 3) against some fungal species. The synthesis of substituted 2-aminothiophenes was carried out through the most versatile synthetic method developed by Gewald e ...201121831103
Antifungal activity and chemical composition of essential oils from Smyrnium olusatrum L. (Apiaceae) from Italy and Portugal.The essential oils and supercritical CO(2) extracts of wild Smyrnium olusatrum L. growing in Sardinia (Italy) and in Portugal were investigated. For the study, oils were isolated from total plant aerial part (umbels containing seeds). The content of ß-phellandrene (67.3% vs. 42.7%) and a-pinene (31.9% vs. 1.2%), respectively, the main components of Portuguese and Italian essential oils, declined during the maturation stage of the umbels. Contrarily, some other important components, particularly ...201121902563
Antifungal activity and chemical composition of essential oils from Smyrnium olusatrum L. (Apiaceae) from Italy and Portugal.The essential oils and supercritical CO(2) extracts of wild Smyrnium olusatrum L. growing in Sardinia (Italy) and in Portugal were investigated. For the study, oils were isolated from total plant aerial part (umbels containing seeds). The content of ß-phellandrene (67.3% vs. 42.7%) and a-pinene (31.9% vs. 1.2%), respectively, the main components of Portuguese and Italian essential oils, declined during the maturation stage of the umbels. Contrarily, some other important components, particularly ...201121902563
Broad spectrum antidermatophytic drug for the control of tinea infection in human beings.During antifungal evaluation of various plant extracts, free and bound flavonoids of Piper betle were found to be most effective as an antidermatophytic against human pathogenic dermatophytes Trichophyton rubrum, Trichophyton mentagrophytes, Microsporum gypseum and Candida albicans. Dermatophytic fungi cause both superficial and internal mycoses. These mycoses, although normally not lethal, are unpleasant and difficult to cure and cause considerable financial losses. Earlier workers prove that a ...201121929713
Broad spectrum antidermatophytic drug for the control of tinea infection in human beings.During antifungal evaluation of various plant extracts, free and bound flavonoids of Piper betle were found to be most effective as an antidermatophytic against human pathogenic dermatophytes Trichophyton rubrum, Trichophyton mentagrophytes, Microsporum gypseum and Candida albicans. Dermatophytic fungi cause both superficial and internal mycoses. These mycoses, although normally not lethal, are unpleasant and difficult to cure and cause considerable financial losses. Earlier workers prove that a ...201121929713
anthraquinone profile, antioxidant and antimicrobial properties of bark extracts of rhamnus catharticus and r. orbiculatus.the anthraquinone profile, antioxidant and antimicrobial activities as well as the total phenol and total flavonoid contents were determined in methanol extracts of the barks of rhamnus catharticus l. and r. orbiculatus bornm. the most abundant anthraquinone derivatives in r. catharticus were physcion (67.8%) and emodin (26.2%), while r. orbiculatus contained mostly physcion (81.3%) and chrysophanol (14.6%). r. catharticus displayed better activity in the beta-carotene-linoleic acid assay, as we ...201121941897
anthraquinone profile, antioxidant and antimicrobial properties of bark extracts of rhamnus catharticus and r. orbiculatus.the anthraquinone profile, antioxidant and antimicrobial activities as well as the total phenol and total flavonoid contents were determined in methanol extracts of the barks of rhamnus catharticus l. and r. orbiculatus bornm. the most abundant anthraquinone derivatives in r. catharticus were physcion (67.8%) and emodin (26.2%), while r. orbiculatus contained mostly physcion (81.3%) and chrysophanol (14.6%). r. catharticus displayed better activity in the beta-carotene-linoleic acid assay, as we ...201121941897
design, synthesis and antifungal activity of some new imidazole and triazole derivatives.triazole and imidazole are incorporated into the structures of many antifungal compounds. in this study a novel series of 1,2,4-triazole, imidazole, benzoimidazole, and benzotriazole derivatives was designed as inhibitors of cytochrome p450 14α-demethylase (14dm). these structures were docked into the active site of mt-cyp51, using autodock program. sixteen compounds with the best binding energy were synthesized. the chemical structures of the new compounds were confirmed by elemental and spectr ...201121984016
design, synthesis and antifungal activity of some new imidazole and triazole derivatives.triazole and imidazole are incorporated into the structures of many antifungal compounds. in this study a novel series of 1,2,4-triazole, imidazole, benzoimidazole, and benzotriazole derivatives was designed as inhibitors of cytochrome p450 14α-demethylase (14dm). these structures were docked into the active site of mt-cyp51, using autodock program. sixteen compounds with the best binding energy were synthesized. the chemical structures of the new compounds were confirmed by elemental and spectr ...201121984016
Difference in keratinase activity of dermatophytes at different environmental conditions is an attribute of adaptation to parasitism.Dermatophytes are a group of morphologically and physiologically related moulds, which cause well-defined infection called dermatophytosis. The enzymatic ability of fungi to decompose keratin has long been interpreted as a key innovation in the evolution of animal dermatology. In the present study, keratinase activity profile among Trichophyton mentagrophytes, Trichophyton rubrum, Microsporum canis and Microsporum gypseum isolated on keratin substrates such as human hair, human nail and chicken ...201122032519
Difference in keratinase activity of dermatophytes at different environmental conditions is an attribute of adaptation to parasitism.Dermatophytes are a group of morphologically and physiologically related moulds, which cause well-defined infection called dermatophytosis. The enzymatic ability of fungi to decompose keratin has long been interpreted as a key innovation in the evolution of animal dermatology. In the present study, keratinase activity profile among Trichophyton mentagrophytes, Trichophyton rubrum, Microsporum canis and Microsporum gypseum isolated on keratin substrates such as human hair, human nail and chicken ...201122032519
mating genes of the trichophyton mentagrophytes complex.the mating type (-)-specific gene of the alpha-box and the mating type (+)-specific gene of the high-mobility group (hmg) dna-binding domain were confirmed in zoophilic dematophytes of arthroderma simii and a. vanbreuseghemii. the sequence of the alpha-box gene was 1,375 bp, containing 2 exons (from 172 to 463 bp and from 513 to 1,375 bp) in the a. simii (-) mating type strain and 1,380 bp, containing 2 exons (from 177 to 468 bp and from 518 to 1,380 bp) in the a. vanbreuseghemii (-) mating type ...201122057847
mating genes of the trichophyton mentagrophytes complex.the mating type (-)-specific gene of the alpha-box and the mating type (+)-specific gene of the high-mobility group (hmg) dna-binding domain were confirmed in zoophilic dematophytes of arthroderma simii and a. vanbreuseghemii. the sequence of the alpha-box gene was 1,375 bp, containing 2 exons (from 172 to 463 bp and from 513 to 1,375 bp) in the a. simii (-) mating type strain and 1,380 bp, containing 2 exons (from 177 to 468 bp and from 518 to 1,380 bp) in the a. vanbreuseghemii (-) mating type ...201122057847
antifungal property of quaternized chitosan and its derivatives.five water-soluble chitosan derivatives were carried out by quaternizing either iodomethane or n-(3-chloro-2-hydroxypropyl) trimethylammonium chloride (quat188) as a quaternizing agent under basic condition. the degree of quaternization (dq) ranged between 28±2% and 90±2%. the antifungal activity was evaluated by using disc diffusion method, minimum inhibitory concentration (mic) and minimum fungicidal concentration (mfc) methods against trichophyton rubrum (t. rubrum), trichophyton mentagrophyt ...201222100980
antifungal property of quaternized chitosan and its derivatives.five water-soluble chitosan derivatives were carried out by quaternizing either iodomethane or n-(3-chloro-2-hydroxypropyl) trimethylammonium chloride (quat188) as a quaternizing agent under basic condition. the degree of quaternization (dq) ranged between 28±2% and 90±2%. the antifungal activity was evaluated by using disc diffusion method, minimum inhibitory concentration (mic) and minimum fungicidal concentration (mfc) methods against trichophyton rubrum (t. rubrum), trichophyton mentagrophyt ...201222100980
preparation and evaluation of dermal delivery system of griseofulvin containing vitamin e-tpgs as penetration enhancer.griseofulvin, an antifungal agent, is a bcs class ii drug slowly, erratically, and incompletely absorbed from the gastrointestinal tract in humans. the clinical failure of the conventional oral therapy of griseofulvin is most likely attributed to its poor solubility and appreciable inter- and intra-subject variation in bioavailability from different commercial products. moreover, the conventional oral therapy is associated with numerous adverse effects and interactions with other drugs. the purp ...201122130790
preparation and evaluation of dermal delivery system of griseofulvin containing vitamin e-tpgs as penetration enhancer.griseofulvin, an antifungal agent, is a bcs class ii drug slowly, erratically, and incompletely absorbed from the gastrointestinal tract in humans. the clinical failure of the conventional oral therapy of griseofulvin is most likely attributed to its poor solubility and appreciable inter- and intra-subject variation in bioavailability from different commercial products. moreover, the conventional oral therapy is associated with numerous adverse effects and interactions with other drugs. the purp ...201122130790
Assessment of antimicrobial, insecticidal and genotoxic effects of Melia azedarach L. (chinaberry) naturalized in Anatolia.In this study, antibacterial, antifungal, insecticidal and genotoxic activities of the fruit and leaf extracts of Melia azedarach of Turkish origin were evaluated for the first time. The antimicrobial activity was assessed against Gram (+) and ( - ) bacteria, four Candida species and three dermatophytic fungus (Trichophyton rubrum, Epidermophyton floccosum and Microsporum gypseum). The insecticidal activity of the methanolic fruit extract was performed against the larvae of Aedes aegpyti, Culex ...201122149768
Assessment of antimicrobial, insecticidal and genotoxic effects of Melia azedarach L. (chinaberry) naturalized in Anatolia.In this study, antibacterial, antifungal, insecticidal and genotoxic activities of the fruit and leaf extracts of Melia azedarach of Turkish origin were evaluated for the first time. The antimicrobial activity was assessed against Gram (+) and ( - ) bacteria, four Candida species and three dermatophytic fungus (Trichophyton rubrum, Epidermophyton floccosum and Microsporum gypseum). The insecticidal activity of the methanolic fruit extract was performed against the larvae of Aedes aegpyti, Culex ...201122149768
chemical and biological diversity in fourteen selections of four ocimum species.biomass, essential oil yield, essential oil composition diversity, and antibacterial and antifungal activities of 14 selections of 4 ocimum species [ocimum basilicum l. (selections: t1-t10), o. gratissimum l. (selections: t11-t12), o. tenuiflorum l.f., syn. o. sanctum l. (selection: t13) and o. kilimandscharicum baker ex. guerke (selection: t14)] were investigated. o. basilicum selections t9 (methyl chavicol: 87.0%) and t10 {(z)- and (e)-methyl cinnamate: 69.1%} produced higher biomass (67.8 and ...201122224293
chemical and biological diversity in fourteen selections of four ocimum species.biomass, essential oil yield, essential oil composition diversity, and antibacterial and antifungal activities of 14 selections of 4 ocimum species [ocimum basilicum l. (selections: t1-t10), o. gratissimum l. (selections: t11-t12), o. tenuiflorum l.f., syn. o. sanctum l. (selection: t13) and o. kilimandscharicum baker ex. guerke (selection: t14)] were investigated. o. basilicum selections t9 (methyl chavicol: 87.0%) and t10 {(z)- and (e)-methyl cinnamate: 69.1%} produced higher biomass (67.8 and ...201122224293
in vitro microbiological evaluation of 1,1'-(5,5'-(1,4-phenylene)bis(3-aryl-1h-pyrazole-5,1-(4h,5h)-diyl))diethanones, novel bisacetylated pyrazoles.novel 1,1'-(5,5'-(1,4-phenylene)bis(3-aryl-1h-pyrazole-5,1-(4h,5h)-diyl))diethanones 7-12 were tested for their antimicrobial activity by disc diffusion and twofold serial dilution method against the tested bacterial and fungal strains. compounds 7 against micrococcus luteus, 8 against β-heamolytic streptococcus, m. luteus, klebsiella pneumonia, microsporum gypseum, 9 against staphylococcus aureus, shigella flexneri, vibreo cholerae, pseudomonas aeruginosa, aspergillus flavus, mucor indicus, 10 ...201122373408
in vitro microbiological evaluation of 1,1'-(5,5'-(1,4-phenylene)bis(3-aryl-1h-pyrazole-5,1-(4h,5h)-diyl))diethanones, novel bisacetylated pyrazoles.novel 1,1'-(5,5'-(1,4-phenylene)bis(3-aryl-1h-pyrazole-5,1-(4h,5h)-diyl))diethanones 7-12 were tested for their antimicrobial activity by disc diffusion and twofold serial dilution method against the tested bacterial and fungal strains. compounds 7 against micrococcus luteus, 8 against β-heamolytic streptococcus, m. luteus, klebsiella pneumonia, microsporum gypseum, 9 against staphylococcus aureus, shigella flexneri, vibreo cholerae, pseudomonas aeruginosa, aspergillus flavus, mucor indicus, 10 ...201122373408
semisynthesis and antimicrobial activity of novel guttiferone-a derivatives.six derivatives of guttiferone-a (lfqm-79, 80, 81, 82, 113 and 114) were synthesized and evaluated for their antimicrobial activity against the opportunistic or pathogenic fungi candida albicans (atcc 09548), candida glabrata (atcc 90030), candida krusei (atcc 6258), candida parapsilosis (atcc 69548), candida tropicalis (atcc 750), cryptococcus neoformans (atcc 90012), trichophyton tonsurans, microsporum gypseum and also against the opportunistic and pathogenic gram-positive bacteria staphylococ ...201222401914
semisynthesis and antimicrobial activity of novel guttiferone-a derivatives.six derivatives of guttiferone-a (lfqm-79, 80, 81, 82, 113 and 114) were synthesized and evaluated for their antimicrobial activity against the opportunistic or pathogenic fungi candida albicans (atcc 09548), candida glabrata (atcc 90030), candida krusei (atcc 6258), candida parapsilosis (atcc 69548), candida tropicalis (atcc 750), cryptococcus neoformans (atcc 90012), trichophyton tonsurans, microsporum gypseum and also against the opportunistic and pathogenic gram-positive bacteria staphylococ ...201222401914
dermatophyte infections mimicking other skin diseases: a 154-person case survey of tinea atypica in the district of cagliari (italy).although usually simple, the diagnosis of dermatophyte infection is sometimes neglected. an observational study has been realized to evaluate the role of corticosteroid exposure (tinea incognito) and of other primary characteristics of the dermatophytosis that from onset mimic other diseases and mislead an unexperienced physician.201222435428
dermatophyte infections mimicking other skin diseases: a 154-person case survey of tinea atypica in the district of cagliari (italy).although usually simple, the diagnosis of dermatophyte infection is sometimes neglected. an observational study has been realized to evaluate the role of corticosteroid exposure (tinea incognito) and of other primary characteristics of the dermatophytosis that from onset mimic other diseases and mislead an unexperienced physician.201222435428
kerion celsi due to arthroderma incurvatum infection in a sri lankan child: species identification and analysis of area-dependent genetic polymorphism.a three-year-old sri lankan boy residing in japan developed a nodule on his scalp after visiting sri lanka. two months later, the lesion increased in size to 22 × 19 mm(2), and was identified as an erythematous nodule with alopecia. direct examination of the infected hair shafts indicated fungal hyphae outside the shafts. the fungus was identified as microsporum gypseum following mycological examination. the sequence of the internal transcribed spacer 1 region of ribosomal rna gene (its1 rdna) e ...201222443310
kerion celsi due to arthroderma incurvatum infection in a sri lankan child: species identification and analysis of area-dependent genetic polymorphism.a three-year-old sri lankan boy residing in japan developed a nodule on his scalp after visiting sri lanka. two months later, the lesion increased in size to 22 × 19 mm(2), and was identified as an erythematous nodule with alopecia. direct examination of the infected hair shafts indicated fungal hyphae outside the shafts. the fungus was identified as microsporum gypseum following mycological examination. the sequence of the internal transcribed spacer 1 region of ribosomal rna gene (its1 rdna) e ...201222443310
pathology in practice. microsporum gypseum infection. 201222471823
pathology in practice. microsporum gypseum infection. 201222471823
antimicrobial and antioxidant activities of gentianella multicaulis collected on the andean slopes of san juan province, argentina.the infusion of the aerial parts of gentianella multicaulis (gillies ex griseb.) fabris (gentianaceae), locally known as 'nencia', is used in san juan province, argentina, as stomachic and as a bitter tonic against digestive and liver problems. the bioassay-guided isolation of g. multicaulis extracts and structural elucidation of the main compounds responsible for the antifungal and free radical scavenging activities were performed. the extracts had strong free radical scavenging effects in the ...201222486039
antimicrobial and antioxidant activities of gentianella multicaulis collected on the andean slopes of san juan province, argentina.the infusion of the aerial parts of gentianella multicaulis (gillies ex griseb.) fabris (gentianaceae), locally known as 'nencia', is used in san juan province, argentina, as stomachic and as a bitter tonic against digestive and liver problems. the bioassay-guided isolation of g. multicaulis extracts and structural elucidation of the main compounds responsible for the antifungal and free radical scavenging activities were performed. the extracts had strong free radical scavenging effects in the ...201222486039
prevalence of keratinophilic fungi in soils of st. kitts and nevis.information on the prevalence of keratinophilic fungi in west indies is scanty. occurrence of keratinophilic fungi in soils of st. kitts and nevis has not been investigated previously.201222505445
prevalence of keratinophilic fungi in soils of st. kitts and nevis.information on the prevalence of keratinophilic fungi in west indies is scanty. occurrence of keratinophilic fungi in soils of st. kitts and nevis has not been investigated previously.201222505445
antifungal activity of lactobacillus against microsporum canis, microsporum gypseum and epidermophyton floccosum.a total of 220 lactic acid bacteria isolates were screened for antifungal activity using aspergillus fumigatus and aspergillus niger as the target strains. four lactobacillus strains exhibited strong inhibitory activity on agar surfaces. all four were also identified as having strong inhibitory activity against the human pathogenic fungi microsporum canis, microsporum gypseum and epidermophyton floccosum. one of the four lactobacilli, namely lb. reuteri ee1p exhibited the most inhibition against ...201722539027
antifungal activity of lactobacillus against microsporum canis, microsporum gypseum and epidermophyton floccosum.a total of 220 lactic acid bacteria isolates were screened for antifungal activity using aspergillus fumigatus and aspergillus niger as the target strains. four lactobacillus strains exhibited strong inhibitory activity on agar surfaces. all four were also identified as having strong inhibitory activity against the human pathogenic fungi microsporum canis, microsporum gypseum and epidermophyton floccosum. one of the four lactobacilli, namely lb. reuteri ee1p exhibited the most inhibition against ...201722539027
dermatophytic profile of jaipur (rajasthan).out of 410 clinically diagnosed cases of superficial mycoses encountered during 1985 - 87, direct koh mounts were positive in 250 (62.19%) cases and the cultures were positive in 123 (30.00%) cases. the organisms isolated included trichophyton rubrum (36.58%). t. simii (32.52%), t.mentagrophytes (12.19%), c.tropicum (8.13%), microsporum gypseum (6.50%), epidermophyton floccossum (2.43%), t. violaceum (0.81%) and candida albicans (0.81%). majority of cases occurred among the age group of 21 - 30 ...199522556696
dermatophytic profile of jaipur (rajasthan).out of 410 clinically diagnosed cases of superficial mycoses encountered during 1985 - 87, direct koh mounts were positive in 250 (62.19%) cases and the cultures were positive in 123 (30.00%) cases. the organisms isolated included trichophyton rubrum (36.58%). t. simii (32.52%), t.mentagrophytes (12.19%), c.tropicum (8.13%), microsporum gypseum (6.50%), epidermophyton floccossum (2.43%), t. violaceum (0.81%) and candida albicans (0.81%). majority of cases occurred among the age group of 21 - 30 ...199522556696
comparative efficacy of four antimicrobials against keratophilic fungi.comparative efficacy of miconazole nitrate, graphite, thuja and chrysorobin ointments was assessed against three keratinophillic fungi, viz., trichophyton terrestris, chrysosporium tropicum and microsporum gypseum. all the test fungi were sensitive to the anti microbials tested in the present study. miconazole nitrate, showed the maximum activity followed by graphite, and thuja, whereas the minimum inhibition was exhibited by chrysorobin. among all the test fungi, t. terrestris was found to be t ...199522556711
comparative efficacy of four antimicrobials against keratophilic fungi.comparative efficacy of miconazole nitrate, graphite, thuja and chrysorobin ointments was assessed against three keratinophillic fungi, viz., trichophyton terrestris, chrysosporium tropicum and microsporum gypseum. all the test fungi were sensitive to the anti microbials tested in the present study. miconazole nitrate, showed the maximum activity followed by graphite, and thuja, whereas the minimum inhibition was exhibited by chrysorobin. among all the test fungi, t. terrestris was found to be t ...199522556711
epidemiology of dermatophytoses in crete, greece between 2004 and 2010.the present work was undertaken in order to study the epidemiology of dermatophytoses in the island of crete, greece, over a 7-year period (2004-2010) and to compare the results with those reported earlier from this region and from other parts of the world.201222648332
epidemiology of dermatophytoses in crete, greece between 2004 and 2010.the present work was undertaken in order to study the epidemiology of dermatophytoses in the island of crete, greece, over a 7-year period (2004-2010) and to compare the results with those reported earlier from this region and from other parts of the world.201222648332
an improved molecular diagnostic assay for canine and feline dermatophytosis.the few studies attempting to specifically characterize dermatophytes from hair samples of dogs and cats using pcr-based methodology relied on sequence-based analysis of selected genetic markers. the aim of the present investigation was to establish and evaluate a pcr-based approach employing genetic markers of nuclear dna for the specific detection of dermatophytes on such specimens. using 183 hair samples, we directly compared the test results of our one-step and nested-pcr assays with those b ...201322686247
an improved molecular diagnostic assay for canine and feline dermatophytosis.the few studies attempting to specifically characterize dermatophytes from hair samples of dogs and cats using pcr-based methodology relied on sequence-based analysis of selected genetic markers. the aim of the present investigation was to establish and evaluate a pcr-based approach employing genetic markers of nuclear dna for the specific detection of dermatophytes on such specimens. using 183 hair samples, we directly compared the test results of our one-step and nested-pcr assays with those b ...201322686247
antifungal activity of arctotis arctotoides (l.f.) o. hoffm. and gasteria bicolor haw. against opportunistic fungi associated with human immunodeficiency virus/acquired immunodeficiency syndrome.in south africa where many patients are immunocompromised as a result of the aids pandemic, opportunistic fungal infections such as candidiasis caused mainly by candida albicans are common. arctotis arctotoides and gasteria bicolor are two plants which are frequently and commonly used in traditional medicine in the treatment of hiv patients.201222701287
antifungal activity of arctotis arctotoides (l.f.) o. hoffm. and gasteria bicolor haw. against opportunistic fungi associated with human immunodeficiency virus/acquired immunodeficiency syndrome.in south africa where many patients are immunocompromised as a result of the aids pandemic, opportunistic fungal infections such as candidiasis caused mainly by candida albicans are common. arctotis arctotoides and gasteria bicolor are two plants which are frequently and commonly used in traditional medicine in the treatment of hiv patients.201222701287
bio-efficacy of dioscorea pentaphylla from midmid-western ghats, india.antibacterial and antifungal activity of crude extracts of medicinally important and traditionally used yam plant, dioscorea pentaphylla, from mid-western ghats was evaluated against 27 bacterial and 5 fungal clinical strains collected of the patients from infectious sources. the clinical strains belonging to their respective species showed concentration-dependent susceptibility toward crude petroleum ether extract, chloroform extract and methanol extract at 100 μg/100 μl. the extracts exhibited ...201222778504
bio-efficacy of dioscorea pentaphylla from midmid-western ghats, india.antibacterial and antifungal activity of crude extracts of medicinally important and traditionally used yam plant, dioscorea pentaphylla, from mid-western ghats was evaluated against 27 bacterial and 5 fungal clinical strains collected of the patients from infectious sources. the clinical strains belonging to their respective species showed concentration-dependent susceptibility toward crude petroleum ether extract, chloroform extract and methanol extract at 100 μg/100 μl. the extracts exhibited ...201222778504
synthesis, characterization, and antimicrobial evaluation of some new hydrazinecarbothioamide, 1,2,4-triazole and 1,3,4-thiadiazole derivatives.in this work, we reported the synthesis and evaluation of antibacterial and antifungal activities of three new compound series obtained from 6-(phenyl/4-chlorophenyl)imidazo[2,1-b]thiazole-3-acetic acid hydrazide: 2-{[6-(phenyl/4-chlorophenyl)imidazo[2,1-b]thiazol-3-yl]acetyl}-n-alkyl/arylhydrazinecarbothioamides (2a-d), 4-alkyl/aryl-2,4-dihydro-5-{[6-(phenyl/4-chlorophenyl)imidazo[2,1-b]thiazol-3-yl]methyl}-3h-1,2,4-triazole-3-thiones (3a-n), and 2-alkyl/arylamino-5-{[6-(phenyl/4-chlorophenyl)i ...201322845330
synthesis, characterization, and antimicrobial evaluation of some new hydrazinecarbothioamide, 1,2,4-triazole and 1,3,4-thiadiazole derivatives.in this work, we reported the synthesis and evaluation of antibacterial and antifungal activities of three new compound series obtained from 6-(phenyl/4-chlorophenyl)imidazo[2,1-b]thiazole-3-acetic acid hydrazide: 2-{[6-(phenyl/4-chlorophenyl)imidazo[2,1-b]thiazol-3-yl]acetyl}-n-alkyl/arylhydrazinecarbothioamides (2a-d), 4-alkyl/aryl-2,4-dihydro-5-{[6-(phenyl/4-chlorophenyl)imidazo[2,1-b]thiazol-3-yl]methyl}-3h-1,2,4-triazole-3-thiones (3a-n), and 2-alkyl/arylamino-5-{[6-(phenyl/4-chlorophenyl)i ...201322845330
formamido-diterpenes from the south china sea sponge acanthella cavernosa.seven new formamido-diterpenes, cavernenes a-d (1-4), kalihinenes e and f (5-6), and kalihipyran c (7), together with five known compounds (8-12), were isolated from the south china sea sponge acanthella cavernosa. structures were established using ir, hresims, 1d and 2d nmr, and single x-ray diffraction techniques. the isolated compounds were assessed for their cytotoxicity against a small panel of human cancer cell lines (hct-116, a549, hela, qgy-7701, and mda-mb-231) with ic(50) values in the ...201222851918
formamido-diterpenes from the south china sea sponge acanthella cavernosa.seven new formamido-diterpenes, cavernenes a-d (1-4), kalihinenes e and f (5-6), and kalihipyran c (7), together with five known compounds (8-12), were isolated from the south china sea sponge acanthella cavernosa. structures were established using ir, hresims, 1d and 2d nmr, and single x-ray diffraction techniques. the isolated compounds were assessed for their cytotoxicity against a small panel of human cancer cell lines (hct-116, a549, hela, qgy-7701, and mda-mb-231) with ic(50) values in the ...201222851918
antimicrobial activity of bioactive compounds and leaf extracts in jatropha tanjorensis.jatropha tanjorensis was investigated scientifically to generate evidence for the efficacies reported in traditional systems and the results are given here.201222884742
antimicrobial activity of bioactive compounds and leaf extracts in jatropha tanjorensis.jatropha tanjorensis was investigated scientifically to generate evidence for the efficacies reported in traditional systems and the results are given here.201222884742
essential oil of azorella cryptantha collected in two different locations from san juan province, argentina: chemical variability and anti-insect and antimicrobial activities.the essential oils (eos) of two populations of azorella cryptantha (clos) reiche, a native species from san juan province, were obtained by hydrodistillation in a clevenger-type apparatus and characterized by gc-fid and gc/ms analyses. the compounds identified amounted to 92.3 and 88.7% of the total oil composition for a. cryptantha from bauchaceta (ac-bau) and agua negra (ac-an), respectively. the eo composition for the two populations was similar, although with differences in the identity and ...201222899606
essential oil of azorella cryptantha collected in two different locations from san juan province, argentina: chemical variability and anti-insect and antimicrobial activities.the essential oils (eos) of two populations of azorella cryptantha (clos) reiche, a native species from san juan province, were obtained by hydrodistillation in a clevenger-type apparatus and characterized by gc-fid and gc/ms analyses. the compounds identified amounted to 92.3 and 88.7% of the total oil composition for a. cryptantha from bauchaceta (ac-bau) and agua negra (ac-an), respectively. the eo composition for the two populations was similar, although with differences in the identity and ...201222899606
dermatophytes from skin lesions of domestic animals in nsukka, enugu state, nigeria.dermatophytes are well-recognized cutaneous fungi with public health implications. in nigeria, several studies have been carried out on dermatophytosis in humans; however, data on dermatophytes in animals are lacking.201222913664
Displaying items 1101 - 1200 of 1457