Publications
| Title | Abstract | Year Filter | PMID(sorted ascending) Filter |
|---|
| the origin of spontaneous heteroploids in the progeny of diploid, triploid, and tetraploid axolotl females. | 2006 | 13698113 | |
| internal factors influencing normal and compensatory growth of the axolotl pronephros. | 1960 | 13701095 | |
| microchemical deoxyribonucleic acid determination in individual cells. | a method for the quantitative determination of dna in the 50 to 500 micromicrog. range is presented. cells or cell nuclei are isolated individually from fixed tissue by means of micromanipulation. the tissue units in question are extracted in an oil chamber with deoxyribonuclease solution. the extracts are evaporated to dryness and redissolved to lens-shaped drops, the dna contents of which are determined by a photographic-photometric procedure in ultraviolet light. determinations on calf thymoc ... | 1961 | 13725762 |
| [intracellular electrogram (i.c.e.), external electrogram and mechanogram of the heart of the axolotl (amblystoma tigrinum)]. | 1960 | 13759035 | |
| the self-differentiation of the paddle-shaped limb regenerate, transplanted with normal and reversed proximo-distal orientation after removal of the digital plate (ambystoma mexicanum). | 1961 | 13770156 | |
| further investigation of the effect of roentgen irradiation upon the development of the head of the young axolotl. | 1959 | 13805393 | |
| reaction of limb regenerates of adult axolotl (siredon mexicanum) to x-irradiation. | 1960 | 13805394 | |
| roentgen regression and roentgen stimulation in axolotl (siredon mexicanum). | 1959 | 13805395 | |
| an experimental analysis of regional organization in the regenerating fore limb of the axolotl (ambystoma mexicanum). | 2006 | 13821173 | |
| [xenoplastic transplantation of the caudal bud of urodela embryos on the limb region of anuran embryos (axolotl-discoglossus pictus)]. | 1959 | 13855773 | |
| studies on the maternal effect of the semilethal gene, v, in the mexican axolotl. i. influence of temperature on the expression of the effect. ii. cytological changes in the affected embryos. | 1962 | 13873071 | |
| [culture of ovaries of axolotl on different media]. | 1961 | 13893979 | |
| a study of myofibril sarcomere structure during contraction. | in the present investigation of cross-striated muscle fibers of axolotl, we succeeded in observing in one field of vision of the electron microscope all the stages of myofibril contraction. this allowed us to avoid errors in establishing the sequence of individual contraction stages. our studies reveal a new contraction stage which appears at the shortening of the sarcomere below 74 per cent of the "resting length" but prior to the formation of typical "maximally shortened" sarcomeres, character ... | 1962 | 13898583 |
| nuclear transplantation in the axolotl. | 1962 | 13912738 | |
| [action of myleran on regenerating striated muscle in axolotl]. | 1962 | 13933521 | |
| [cytological effects of myleran on striated muscle of the chick embryo in ovo and the regenerating axolotl tail]. | 1963 | 13969896 | |
| [cytochemistry of the nucleotides and nucleic acids in axolotl liver cells]. | 2006 | 13975042 | |
| localized areas of high alkaline phosphatase activity in the endothelium of arteries in the axolotl. | 1963 | 13984342 | |
| the successive changes in the skin epithelium of the young axolotl (siredon mexicanum) after roentgen irradiation. | 1963 | 14016363 | |
| histochemical localization of beta-glucuronidase in healing wounds of the axolotl. | 1962 | 14039532 | |
| successive changes in the cornea of young axolotl (siredon mexicanum) after x-irradiation. | 1963 | 14075650 | |
| tissue afinities of developing melanophores in the mexican axolotl, siredon mexicanum, shaw. | 1963 | 14085417 | |
| polyploidy in the mexican axolotl (ambystoma mexicanum) resulting from multinucleate ova. | 1963 | 14096187 | |
| [electron microscope studies on degenerative and regenerative processes in severed spinal cord of ambystoma mexicanum]. | 1963 | 14126249 | |
| genetic and experimental studies on a lethal factor (r) in the axolotl which induces abnormalities in the renal system and other organs. | 1964 | 14131450 | |
| the effects of sodium, potassium, and calcium ions on certain expressions of the semilethal gene v in the mexican axolotl, ambystoma (=siredon) mexicanum. | 1964 | 14138973 | |
| [the structure of the hemoglobin of the mexican axolotl. i. chemico-physical properties]. | 1963 | 14153902 | |
| ultrastructural aspects of the nucleo-cytoplasmic relationship of invaginated nuclei in the epidermal cells of the axolotl. | 1964 | 14156467 | |
| [the structure of the hemoglobin of the mexican axolotl. ii. study of the denaturation with alkalies]. | 1963 | 14156753 | |
| tissue environment and morphogenesis of axolotl melanophores. | 1964 | 14164511 | |
| [effect of gamma-butyric acid and picrotoxin on reaction potentials of the tegmentum of the midbrain in frogs and axolotls]. | 2013 | 14165640 | |
| [cellular action of myleran in the axolotl during regeneration]. | 1964 | 14188127 | |
| [persistence of leptospira icterohaemorrhagiae in the axolotl (ambystoma tigrinum)]. | 1963 | 14190217 | |
| the influence of lithium on the competence of the ectoderm in ambystoma mexicanum. | 1964 | 14192053 | |
| a test of the capacity of presumptive somatic cells to transform into primordial germ cells in the mexican axolotl. | 1964 | 14193848 | |
| a microscopic study of chlorpromazine (largactil) treated axolotl larvae. | 1964 | 14208247 | |
| transplantation of nuclei of various cell types from neurulae of the mexican axolotl (ambystoma mexicanum). | 1964 | 14217778 | |
| [dynamics of changes of the nucleic acid content following roentgen-irradiation and depression and restoration of regenerative capacities of axolotl extremities]. | 1964 | 14219603 | |
| new observations concerning roentgen sensitivity of pigment cells in young axolotls (siredon mexicanum). | 1965 | 14245876 | |
| [regenerative processes in the telencephalon of ambystoma mexicanum]. | 1964 | 14248567 | |
| [on causes of lost regenerative capacity of the axolotl extremity after roentgen irradiation]. | 1964 | 14261202 | |
| [regeneration, induced by testis grafts, of irradiated limbs in the axolotl]. | 1965 | 14275976 | |
| [dimensionless characteristics of the duration of mitotic phases of the 1st cleavage division in the axolotl]. | 1965 | 14277315 | |
| spontaneous melanoma in regenerating tails of axolotls. | 1965 | 14299677 | |
| [the epiphysis of axolotl]. | 2007 | 14301966 | |
| [the restoration of regenerative capacity of the extremities in the axolotl, inhibited by x-irradiation, by means of nucleic acids]. | 1964 | 14311043 | |
| the response of the olfactory epithelium of the adult axolotl (siredon mexicanum) to roentgen irradiation. | 1965 | 14320802 | |
| [influence of actinomycin d on the metamorphosis induced by thyroxine in the axolotl]. | 1965 | 14331244 | |
| [compensatory hyperplasia and regeneration in the telencephalon of ambystoma mexicanum following resection of a hemisphere]. | 1964 | 14332323 | |
| [study on the incorporation of s35-labeled sodium sulfate in the cartilage of the axolotl]. | 1965 | 14333227 | |
| the regulation of urea-biosynthesis enzymes in vertebrates. | 1. carbamoyl phosphate synthetase, ornithine transcarbamoylase, the arginine-synthetase system and arginase were measured in the livers of ammoniotelic, ureotelic and uricotelic animals. the chelonian reptiles, whose nitrogen excretory patterns vary according to the habitat, and the mexican axolotl, a neotenic species, were also studied. 2. the levels of the activities of the first three enzymes mentioned correlate with the amount of nitrogen excreted as urea. 3. the terrestrial turtle, which ex ... | 1965 | 14343146 |
| [effect of isolated hormones on the experimental development and metamorphosis of the axolotl as a function of a deficiency of the main salts of the medium, potassium and sodium]. | 1954 | 14364939 | |
| [malignant neoplasms produced in axolotl with crystals of methylcholanthrene]. | 1954 | 14365611 | |
| [effect of isolated hormones on the development and experimental metamorphosis of the axolotl as a function of deficiency of the principal salts of the medum]. | 1954 | 14376947 | |
| a maternal effect of a gene (f) for a fluid imbalance in the mexican axolotl. | 1960 | 14405375 | |
| [regeneration of the extremities of the adult axolotl, at the expense of embryonal grafts]. | 1959 | 14414792 | |
| [cytology of the islets of langerhans in the axolotl (siredon mexicanum) and ambyostoma maculatum]. | 1962 | 14455288 | |
| regulative germ cell specification in axolotl embryos: a primitive trait conserved in the mammalian lineage. | how germ cells are specified in the embryos of animals has been a mystery for decades. unlike most developmental processes, which are highly conserved, embryos specify germ cells in very different ways. curiously, in mouse embryos germ cells are specified by extracellular signals; they are not autonomously specified by maternal germ cell determinants (germ plasm), as are the germ cells in most animal model systems. we have developed the axolotl (ambystoma mexicanum), a salamander, as an experime ... | 2003 | 14511484 |
| characterization of glycosaminoglycans during tooth development and mineralization in the axolotl, ambystoma mexicanum. | glycosaminoglycans (gags) involved in the formation of the teeth of ambystoma mexicanum were located and characterized with the cuprolinic blue (cb) staining method and transmission electron microscopy (tem). glycosaminoglycan-cuprolinic blue precipitates (gagcb) were found in different compartments of the mineralizing tissue. various populations of elongated gagcb could be discriminated both according to their size and their preferential distribution in the extracellular matrix (ecm). gagcb pop ... | 2003 | 14517102 |
| axolotl pronephric duct migration requires an epidermally derived, laminin 1-containing extracellular matrix and the integrin receptor alpha6beta1. | the epidermis overlying the migrating axolotl pronephric duct is known to participate in duct guidance. this epidermis deposits an extracellular matrix onto the migrating duct and its pathway that is a potential source of directional guidance cues. the role of this matrix in pronephric duct guidance was assayed by presenting matrix deposited on microcarriers directly to migrating pronephric ducts in situ. we found that reorientation of extracellular-matrix-bearing carriers prior to their present ... | 2003 | 14522870 |
| the axolotl (ambystoma mexicanum), a neotenic amphibian, expresses functional thyroid hormone receptors. | neotenic amphibians such as the axolotl (ambystoma mexicanum) are often unable to undergo metamorphosis under natural conditions. it is thought that neoteny represents a deviation from the standard course of amphibian ontogeny, affecting the thyroid axis at different levels from the central nervous system to peripheral organs. thyroid hormone receptors (trs) that bind the thyroid hormone (th) t(3) have been described in axolotl. however, the full sequences of tr were needed to better characteriz ... | 2004 | 14576183 |
| gustatory neurons derived from epibranchial placodes are attracted to, and trophically supported by, taste bud-bearing endoderm in vitro. | taste buds are multicellular receptor organs innervated by the viith, ixth, and xth cranial nerves. in most vertebrates, taste buds differentiate after nerve fibers have reached the lingual epithelium, suggesting that nerves induce taste buds. however, under experimental conditions, taste buds of amphibians develop independently of innervation. thus, rather than being induced by nerves, the developing taste periphery likely regulates ingrowing nerve fibers. to test this idea, we devised a cultur ... | 2003 | 14651931 |
| endogenous electric fields in embryos during development, regeneration and wound healing. | all embryos that have been investigated drive ionic currents through themselves and these currents will generate internal electric fields. here, those examples in which such fields have been measured directly are discussed. the first such measurements were made in chick embryos and about 20 mv mm(-1) was measured near the posterior intestinal portal in 2-4 day-old embryos. this electric field is important for the development of tail structures because reducing its magnitude results in abnormal t ... | 2003 | 14690282 |
| neurotrophin-independent attraction of growing sensory and motor axons towards developing xenopus limb buds in vitro. | the mechanisms for directing axons to their targets in developing limbs remain largely unknown though recent studies in mice have demonstrated the importance of neurotrophins in this process. we now report that in co-cultures of larval xenopus laevis limb buds with spinal cords and dorsal root ganglia of xenopus and axolotl (ambystoma mexicanum) axons grow directly to the limb buds over distances of up to 800 microm and in particular to sheets of epidermal cells which migrate away from the limb ... | 2004 | 14697361 |
| identification of angiotensin i in several vertebrate species: its structural and functional evolution. | in order to delineate further the molecular evolution of the renin-angiotensin system in vertebrates, angiotensin i (ang i) has been isolated after incubation of plasma and kidney extracts of emu (dromiceus novaehollandiae), axolotl (ambystoma mexicanum), and sea lamprey (petromyzon marinus). the identified sequences were [asp1, val5, asn9] ang i in emu, [asp1, val5, his9] ang i in axolotl, and [asn1, val5, thr9] ang i in sea lamprey. these results confirmed the previous findings that tetrapods ... | 2004 | 14723880 |
| downregulation of n1 gene expression inhibits the initial heartbeating and heart development in axolotls. | recessive mutant gene c in the axolotl results in a failure of affected embryos to develop contracting hearts. this abnormality can be corrected by treating the mutant heart with rna isolated from normal anterior endoderm or from endoderm conditioned medium. a cdna library was constructed from the total conditioned medium rna using a random priming technique in a pcdnaii vector. we have previously identified a clone (designated as n1) from the constructed axolotl cdna library, which has a unique ... | 2004 | 14729455 |
| combined intrinsic and extrinsic influences pattern cranial neural crest migration and pharyngeal arch morphogenesis in axolotl. | cranial neural crest cells migrate in a precisely segmented manner to form cranial ganglia, facial skeleton and other derivatives. here, we investigate the mechanisms underlying this patterning in the axolotl embryo using a combination of tissue culture, molecular markers, scanning electron microscopy and vital dye analysis. in vitro experiments reveal an intrinsic component to segmental migration; neural crest cells from the hindbrain segregate into distinct streams even in the absence of neigh ... | 2004 | 14738875 |
| injection of exogenous rna in amphibian oocytes leads to rna level fluctuations which are sensitive to cordycepin, an rna chain elongation terminator. | using an in vivo heterologous system to study the stability of xenopus laevis rna injected into axolotl (ambystoma mexicanum) fertilized eggs, we have previously observed unexpected fluctuations in rna level during early development [andéol et al., differentiation 63 (1998) 69-79]. in this study, we further characterize this phenomenon and establish its existence during axolotl and xenopus oogenesis, suggesting a phylogenetically conserved mechanism. the phenomenon can occur with a variety of ex ... | 2003 | 14746268 |
| [similarity of correlations of the central nervous system with surrounding tissue in ontogenesis and in transplantation in the axolotl]. | 1951 | 14793425 | |
| [factors determining time, place, and type of development of the axial skeleton in axolotl]. | 1951 | 14793442 | |
| [the neurohypophysis of the axolotl (amblystoma mexicanum)]. | 1951 | 14826989 | |
| [effect of the extract of the whole hypophysis combined with other hormones on the development of axolotl]. | 1951 | 14847255 | |
| [action of hormones in function of ph of milieu, on the metamorphosis and development of the axolotl (amblystoma tigrinum green); injections of raceme thyroxin and antuitrin s]. | 1951 | 14849071 | |
| [investigations on the effect of certain iodinated and brominated aromatic compounds on metamorphosis in axolotl]. | 1951 | 14858374 | |
| [brunn reaction in axolotls]. | 1951 | 14859614 | |
| [distribution of ribonucleic acid during extremity regeneration in the axolotl]. | 1951 | 14860074 | |
| [regeneration of roentgen irradiated axolotl extremity in implantation of non-specific tissue]. | 1951 | 14887583 | |
| [functional restoration of denervated extremity in axolotl following roentgen irradiation]. | 1951 | 14906191 | |
| [mechanism of the effect of the central nervous system on surrounding mesenchyma in foundation of axial skeleton in antogenesis in axolotl]. | 1952 | 14906247 | |
| [budding of erythrocytes of non-mammals in culture medium; positive culture of axolotl blood]. | 1951 | 14913009 | |
| influence of local x-ray treatment on development of jaws in young axolotl (siredon mexicanum). | 1952 | 14920442 | |
| [role of the light in early stages of development of axolotl]. | 1952 | 14926635 | |
| [developmental disorders of the vertebral column in axolotl in parts of the body deprived of the spinal cord]. | 1952 | 14936897 | |
| [specific growth rate and the rate of energy metabolism in the ontogenesis of axolotl, ambystoma mexicanum (amphibia: ambystomatidae)]. | concordant changes in the rate of energy metabolism and specific growth rate of axolotls have been revealed. several periods of ontogeny are distinguished, which differ in the ratio of energy metabolism to body weight and, therefore, are described by different allometric equations. it is suggested that the specific growth rate of an animal determines the type of dependence of energy metabolism on body weight. | 2016 | 14994475 |
| retinoic acid repatterns axolotl lateral line receptors. | the effects of all-trans retinoic acid on the development of the lateral line placodes of axolotls was studied. late gastrula and early neurula were exposed to 10(-7) to 10(-5) m retinoic acid for one hour and then reared until they would normally be feeding larvae. as in other vertebrates, the extent of the developmental abnormalities is concentration dependent. those embryos exposed to the highest concentration of retinoic acid failed to form much of the forebrain and midbrain, including the o ... | 2004 | 15005576 |
| activation of cdc2 kinase during meiotic maturation of axolotl oocyte. | activity of cdc2, the universal inducer of mitosis, is regulated by phosphorylation and binding to cyclin b. comparative studies using oocytes from several amphibian species have shown that different mechanisms allow cdc2 activation and entry into first meiotic division. in xenopus, immature oocytes stockpile pre-m-phase promoting factor (mpf) composed of cdc2-cyclin b complexes maintained inactive by thr14 and tyr15 phosphorylation of cdc2. activation of mpf relies on the conversion of pre-mpf ... | 2004 | 15013793 |
| discrimination of conspecific sex and reproductive condition using chemical cues in axolotls ( ambystoma mexicanum). | chemosensory cues play an important role in the daily lives of salamanders, mediating foraging, conspecific recognition, and territorial advertising. we investigated the behavioral effects of conspecific whole-body odorants in axolotls, ambystoma mexicanum, a salamander species that is fully aquatic. we found that males increased general activity when exposed to female odorants, but that activity levels in females were not affected by conspecific odorants. although males showed no difference in ... | 2004 | 15034733 |
| cloning and analysis of axolotl isl2 and lhx2 lim-homeodomain transcription factors. | we cloned and characterized the isl2 and lhx2 lim-homeodomain transcription factors of the mexican salamander, or axolotl, ambystoma mexicanum. using a degenerate pcr approach, partial cdnas representing five lim-homeodomain genes were cloned, indicating conservation of this class of transcription factors in urodeles. full-length cdnas for isl2 and lhx2 were identified and sequenced. the predicted isl2 and lhx2 proteins are well conserved, especially in the lim and dna-binding domains. the isl2 ... | 2004 | 15048808 |
| the epithelia of the protrusible tongue of eurycea longicauda guttolineata (hoolbrook 1838) (urodela: plethodontidae). | in this study the lingual and sublingual glands, the lingual stem and the epithelial surface of the protrusible secondary tongue were investigated by light, scanning and transmission electron microscopy. the quality of the secretions of the epithelia was characterized histochemically. the lingual epithelium is formed by superficial (pavement) and goblet cells and at the margin of the tongue pad are also regions covered by ciliated cells. on the dorsal part of the tongue there are goblet cells of ... | 2003 | 15121544 |
| ultrastructure of the external gill epithelium of the axolotl, ambystoma mexicanum with reference to ionic transport. | the ultrastructure of the external gill epithelium of the axolotl, ambystoma mexicanum, has been examined using conventional transmission electron microscopy to elucidate its role in ionic transport. four cell types are identified in the gill filament and primary gill bar epithelium. these are granular, ciliated, leydig and basal cells. a fifth cell type, the flat mitochondria-rich cell is only found in the gill bar epithelium. the predominant granular cells display microvilli at their surface a ... | 2003 | 15137686 |
| early expression of two tdt isoforms in the hematopoietic system of the mexican axolotl. implications for the evolutionary origin of the n-nucleotide addition. | nontemplate (n)-nucleotide addition by the terminal dideoxynucleotidyl transferase (tdt) at the junctions of rearranging v( d) j gene segments greatly contribute to antigen-receptor diversity. tdt has been identified in several vertebrate species, where it is highly conserved. we report here the isolation of two forms of tdt mrna in an amphibian, the mexican axolotl. the isoform tdt1 shares all of the conserved structural motifs required for tdt activity and displays an average of 50-58% similar ... | 2004 | 15146297 |
| low submetamorphic doses of dexamethasone and thyroxine induce complete metamorphosis in the axolotl (ambystoma mexicanum) when injected together. | entanglement of functions between the adrenal (or interrenal) and thyroid axis has been well described for all vertebrates and can be tracked down up to the level of gene expression. both thyroid hormones and corticosteroids may induce morphological changes leading to metamorphosis climax in the neotenic mexican axolotl (ambystoma mexicanum). in a first series of experiments, metamorphosis was induced with an injection of 25 microg t(4) on three alternate days as judged by a decrease in body wei ... | 2004 | 15158126 |
| coupled amplification and degradation of exogenous rna injected in amphibian oocytes. | the early development of amphibians takes place in the absence of significant transcription and is controlled at the post-transcriptional level. we have reported that in vitro synthesized transcripts injected into axolotl fertilized eggs or oocytes were not continuously degraded as their abundance apparently fluctuated over time, with detected amounts sometimes higher than initial injected amounts. to further characterize this phenomenon, we have co-injected rna chain terminators to prevent rna ... | 2004 | 15161959 |
| patterns of spatial and temporal visceral arch muscle development in the mexican axolotl (ambystoma mexicanum). | vertebrate head development is a classical topic that has received renewed attention during the last decade. most reports use one of a few model organisms (chicken, mouse, zebrafish) and have focused on molecular mechanisms and the role of the neural crest, while cranial muscle development has received less attention. here we describe cranial muscle differentiation and morphogenesis in the mexican axolotl, ambystoma mexicanum. to determine the onset of differentiation we use antibodies against d ... | 2004 | 15216519 |
| expression of a novel cardiac-specific tropomyosin isoform in humans. | tropomyosins are a family of actin binding proteins encoded by a group of highly conserved genes. humans have four tropomyosin-encoding genes: tpm1, tpm2, tpm3, and tpm4, each of which is known to generate multiple isoforms by alternative splicing, promoters, and 3' end processing. tpm1 is the most versatile and encodes a variety of tissue specific isoforms. the tpm1 isoform specific to striated muscle, designated tpm1alpha, consists of 10 exons: 1a, 2b, 3, 4, 5, 6b, 7, 8, and 9a/b. in this stud ... | 2004 | 15249230 |
| cell contact-dependent mechanisms specify taste bud pattern during a critical period early in embryonic development. | after gastrulation, the pharyngeal endoderm is specified to give rise to taste receptor organs without further signaling from other embryonic tissues. we hypothesized that intercellular signaling might be responsible for the specification of taste buds. to test if and when this signaling was occurring, intercellular contacts were transiently disrupted in cultures of pharyngeal endoderm from axolotl embryos, and the number, size, and distribution of taste buds analyzed. disruption of cell contact ... | 2004 | 15254897 |
| characteristics of craniogenesis in the axolotl (ambystoma mexicanum: ambystomatidae) and the role of thyroid hormones in its regulation. | 2017 | 15255140 | |
| a critical role for thrombin in vertebrate lens regeneration. | lens regeneration in urodele amphibians such as the newt proceeds from the dorsal margin of the iris where pigment epithelial cells (pec) re-enter the cell cycle and transdifferentiate into lens. a general problem in regeneration research is to understand how the events of tissue injury or removal are coupled to the activation of plasticity in residual differentiated cells or stem cells. thrombin, a pivotal regulator of the injury response, has been implicated as a regulator of cell cycle re-ent ... | 2004 | 15293804 |
| the scarless heart and the mrl mouse. | the ability to regenerate tissues and limbs in its most robust form is seen in many non-mammalian species. the serendipitous discovery that the mrl mouse has a profound capacity for regeneration in some ways rivalling the classic newt and axolotl species raises the possibility that humans, too, may have an innate regenerative ability. the adult mrl mouse regrows cartilage, skin, hair follicles and myocardium with near perfect fidelity and without scarring. this is seen in the ability to close th ... | 2004 | 15293806 |
| from biomedicine to natural history research: est resources for ambystomatid salamanders. | establishing genomic resources for closely related species will provide comparative insights that are crucial for understanding diversity and variability at multiple levels of biological organization. we developed ests for mexican axolotl (ambystoma mexicanum) and eastern tiger salamander (a. tigrinum tigrinum), species with deep and diverse research histories. | 2004 | 15310388 |