Publications
| Title | Abstract | Year Filter | PMID(sorted ascending) Filter |
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| interference in foraging behaviour of european and american house dust mites dermatophagoides pteronyssinus and dermatophagoides farinae (acari: pyroglyphidae) by catmint, nepeta cataria (lamiaceae). | the european and american house dust mites, dermatophagoides pteronyssinus and d. farinae, have a huge impact upon human health worldwide due to being the most important indoor trigger of atopic diseases such as asthma, rhinitis and atopic dermatitis. preceding studies have shown that the behavioural response of house dust mites towards volatile chemicals from food sources can be assessed using a y-tube olfactometer assay. in the current study, we used this assay to investigate, for the first ti ... | 2012 | 22382713 |
| [a cohort investigation of the allergen and pathogenesis in the patients with allergic rhinitis from three hospital of guangdong province]. | to study the pathogenesis of the patients with allergic rhinitis diagnosed by skin prick test (spt), especially about the epidemiologic data of the involved allergens. | 2011 | 22384564 |
| dermatophagoides in childhood asthma. allergy to dermatophagoides associates more severe childhood asthma with a potential role for acaricides. | to evaluate hypersensitivity to dermatophagoides pteronyssinus (d. pteronyssinus) and dermatophagoides farinae (d. farinae) in pediatric patients with asthma, and the use of acaricides. | 2012 | 22426910 |
| dna/amphiphilic block copolymer nanospheres reduce asthmatic response in a mouse model of allergic asthma. | asthma is a chronic, inflammatory, respiratory disease caused by an abnormal reactivity against allergens. the most promising treatments for asthma are based on specific immunotherapies, but they lack efficiency and can induce deleterious side effects. among new modalities of immunotherapy currently in development, dna vaccination presents a promising approach, as it enables targeted immunotherapy in association with reduced allergenicity. we have developed an innovative, dna-based vaccine again ... | 2012 | 22429072 |
| acaricidal toxicity of 2'-hydroxy-4'-methylacetophenone isolated from angelicae koreana roots and structure-activity relationships of its derivatives. | the acaricidal activities of 2'-hydroxy-4'-methylacetophenone derived from angelica koreana roots and its derivatives against dermatophagoides farinae, dermatophagoides pteronyssinus, and tyrophagus putrescentiae were examined by vapor phase and contact toxicity bioassays. in the vapor phase toxicity bioassay, 2'-methylacetophenone (1.25 μg/cm(2)) was 8.0 times more toxic against d. farinae than benzyl benzoate (10.00 μg/cm(2)), followed by 3'-methylacetophenone (1.26 μg/cm(2)), 4'-methylacetoph ... | 2012 | 22429095 |
| early exposure to probiotics in a canine model of atopic dermatitis has long-term clinical and immunological effects. | probiotics modulate the immune response and may have protective effects against atopic dermatitis (ad). clinical trials using dogs with spontaneous disease are limited by confounding factors such as different diets, environments and sensitizations while a more controlled evaluation is possible using experimental models. a validated model of canine ad showed that early exposure to lactobacillus rhamnosus gg (lgg) significantly decreases allergen-specific ige and partially prevents ad in the first ... | 2012 | 22436376 |
| evaluation of eosinophilic inflammation in a novel murine atopic keratoconjunctivitis model induced by crude dermatophagoides farinae antigen. | the purpose of this study is to conduct a histopathological research of the conjunctival findings and eosinophilic inflammation of novel atopic keratoconjunctivitis in a nc/nga mouse model using crude dermatophagoides farina. | 2012 | 22441637 |
| production of gm-csf mediated by cysteine protease of der f in canine keratinocytes. | house dust mite (hdm) allergens are the most common allergens for induction of ige-mediated hypersensitivity. recently, epicutaneous sensitization with hdm allergens has been emphasized in the development of atopic dermatitis (ad) by producing various soluble factors in keratinocytes. among the soluble factors, gm-csf is a key molecule that activates langerhans cells, antigen-presenting cells in the epidermis. in the present study, we investigated the effects of dermatophagoides farinae (der f) ... | 2012 | 22446400 |
| angelicae dahuricae radix inhibits dust mite extract-induced atopic dermatitis-like skin lesions in nc/nga mice. | we examined whether angelicae dahuricae radix (ar) suppresses the development of atopic dermatitis (ad)-like skin lesions induced by dermatophagoides farinae in nc/nga mice. to investigate the effect of ar, we measured the ad severity score, measured plasma levels of ige and histamine, and performed histological analysis in nc/nga mice. we also confirmed the anti-inflammatory effects of ar by measuring tarc/ccl17 production from lps-treated raw 264.7 cells and mrna levels of tarc and mdc/ccl22 i ... | 2012 | 22454682 |
| [evaluation of exposure and sensitization to house dust mites among rhinitis patients in the steppe environment of inner mongolia]. | to evaluate the correlation of exposure and sensitization to house dust mites among rhinitis patients, and the consistency of skin prick test (spt) and serum specific ige (sige) in the detection of sensitization in a steppe environment of inner mongolia. | 2012 | 22455768 |
| contact blepharoconjunctivitis due to black henna--a case report. | para-phenylenediamine (ppd) can induce immediate or - more often - delayed hypersensitivity. we report the case of 48-year old female admitted to the out-patient allergy clinic a day after her visit in a beauty parlour, where she had her eyelashes and eyebrows dyed with henna. physical examination revealed prominent edema of the upper part of the face including forehead, cheeks and eyes causing severe narrowing of the palpebral chink. skin prick tests (spt) with common allergens were positive fo ... | 2012 | 22492286 |
| acaricidal activities of the active component of lycopus lucidus oil and its derivatives against house dust and stored food mites (arachnida: acari). | recent studies have focused on materials derived from plant extracts as mite control products against house dust and stored food mites because repeated use of synthetic acaricides had led to resistance and unwanted activities on non-target organisms. the aim of this study was to evaluate the acaricidal activity of materials derived from lycopus lucidus against dermatophagoides farinae, d. pteronyssinus and tyrophagus putrescentiae. | 2012 | 22500291 |
| ras guanine nucleotide-releasing protein-4 (rasgrp4) involvement in experimental arthritis and colitis. | rasgrp4 (ras guanine nucleotide-releasing protein-4) is an intracellular, calcium-regulated guanine nucleotide exchange factor and diacylglycerol/phorbol ester receptor expressed in mast cells (mcs) and their progenitors. to study the function of this signaling protein in inflammatory disorders, a homologous recombination approach was used to create a rasgrp4-null c57bl/6 mouse line. the resulting transgenic animals had normal numbers of mcs in their tissues that histochemically and morphologica ... | 2012 | 22511759 |
| the translational repressor t-cell intracellular antigen-1 (tia-1) is a key modulator of th2 and th17 responses driving pulmonary inflammation induced by exposure to house dust mite. | t-cell intracellular antigen-1 (tia-1) is a translational repressor that dampens the production of proinflammatory cytokines and enzymes. in this study we investigated the role of tia-1 in a mouse model of pulmonary inflammation induced by exposure to the allergenic extract (df) of the house dust mite dermatophagoides farinae. when intranasally challenged with a low dose of df, mice lacking tia-1 protein (tia-1(-/-)) showed more severe airway and tissue eosinophilia, infiltration of lung broncho ... | 2012 | 22525013 |
| sequence polymorphisms of der f 1, der p 1, der f 2 and der p 2 from korean house dust mite isolates. | amino acid sequence variations have possible influences on the allergenicity of allergens and may be important factors in allergen standardization. this study was undertaken to investigate the sequence polymorphisms of group 1 and 2 allergens from korean isolates of the house dust mites dermatophagoides farinae and d. pteronyssinus. cdna sequences encoding group 1 and 2 allergens were amplified by rt-pcr and compared the deduced amino acid sequences. der f 1.0101, which appeared in 64.0 % of the ... | 2012 | 22535483 |
| [results of skin prick test in young children with wheezing or allergic diseases]. | to study the characteristics of allergic reactions to common aeroallergens in young children with wheezing or allergic diseases by examining the results of skin prick test in children under 5 years old. | 2012 | 22537958 |
| acetaldehyde at a low concentration synergistically exacerbates allergic airway inflammation as an endocrine-disrupting chemical and as a volatile organic compound. | acetaldehyde is an endocrine-disrupting chemical (edc) and a volatile organic compound (voc). it is also a carcinogen and teratogen that causes bronchoconstriction in a subset of asthmatics. however, the mechanism through which acetaldehyde acts as an edc/voc causing allergic airway inflammation remains unknown. | 2012 | 22538484 |
| prevention and treatment of allergic inflammation by an fcγ-der f2 fusion protein in a murine model of dust mite-induced asthma. | the immunoglobulin e (ige) high-affinity receptor fcεri expressed on mast cells and basophils plays a critical role in triggering allergic disease. the co-aggregation of the fcεri and fcγriib receptors is inhibitory to fcεri signaling and holds great potential for the treatment of ige-mediated allergies. in china, dermatophagoides farinae is a common anaphylaxis trigger. therefore, in this study, the fcγriib-mediated immunomodulating activity of recombinant fcγ-der f2 fusion protein was tested i ... | 2012 | 22539132 |
| limonene inhalation reduces allergic airway inflammation in dermatophagoides farinae-treated mice. | limonene is one of the main flavonoids which is reported to inhibit the inflammatory response by suppressing the production of reactive oxygen species. the aim of this study was to evaluate whether limonene can inhibit dermatophagoides farinae-induced airway hyperresponsiveness (ahr), eosinophilic infiltration and other histological changes in the lung, t helper (th) 2 cytokine production and airway remodeling in a mice model of asthma. treatment with limonene significantly reduced the levels of ... | 2012 | 22564095 |
| [analyzing of the inhaled allergens profiles of 890 allergic rhinitis patients]. | to investigate the inhaled allergens spectrum of 890 allergic rhinitis patients in shanghai, and to provide basic epidemiologic information for the prevention and treatment of allergic rhinitis. | 2012 | 22568255 |
| dust mite species in the households of mite-sensitive dogs with atopic dermatitis. | the presence of important house dust and storage mite species in the microenvironment of atopic dogs has not been thoroughly investigated. | 2012 | 22575020 |
| cloning, bioinformatics analysis, and expression of the dust mite allergen der f 5 of dermatophagoides farinae. | crude extracts of house dust mites are used clinically for diagnosis and immunotherapy of allergic diseases, including bronchial asthma, perennial rhinitis, and atopic dermatitis. however, crude extracts are complexes with non-allergenic antigens and lack effective concentrations of important allergens, resulting in several side effects. dermatophagoides farinae (hughes; acari: pyroglyphidae) is one of the predominant sources of dust mite allergens, which has more than 30 groups of allergen. the ... | 2012 | 22584646 |
| climatic factors correlate with innate immune response in children with dermatophagoides farinae-induced allergic asthma. | to determine the effect of climatic factors on immune markers in children with dermatophagoides farinae induced asthma. | 2012 | 22613438 |
| transcripts of a heterologous gene encoding mite allergen der f 7 are stabilized by codon optimization in aspergillus oryzae. | we have previously demonstrated that transcripts of an at-biased heterologous gene encoding mite allergen der f 7 from dermatophagoides farinae were polyadenylated prematurely within the coding region when native cdna was expressed in aspergillus oryzae, and that this premature polyadenylation was prevented by the codon optimization of the der f 7 gene, resulting in increased steady-state mrna levels. in this study, we tested the stability of transcription products derived from expression constr ... | 2012 | 22644529 |
| [skin prick testing versus immumofluorescence testing for mites allergens]. | to discuss the characteristics of skin prick test (spt) and immumofluorescence method (ifm) in detecting the atopy of dermatophagoides pteronyssinus (dp) and dermatophagoides farinae (df)and explore the relationship of them. | 2012 | 22667132 |
| diet influences growth rates and allergen and endotoxin contents of cultured dermatophagoides farinae and dermatophagoides pteronyssinus house dust mites. | the house dust mites dermatophagoides farinae and dermatophagoides pteronyssinus are cultured to obtain material for the production of allergen extracts for research, diagnostic and immunotherapeutic purposes. | 2012 | 22722476 |
| total ige and allergen-specific ige and igg antibody levels in sera of atopic dermatitis affected and non-affected labrador- and golden retrievers. | canine atopic dermatitis (cad) is an allergic skin disease associated with ige and igg antibodies (ab) to environmental allergens. the aim of this study was to determine which other factors influence serum ab levels in cad-affected and non-affected dogs as this has only been poorly investigated in dogs so far. total and allergen-specific ige levels and dermatophagoides farinae (df)-specific igg1 and igg4 were measured by elisa in sera of 145 cad-affected and 271 non-affected labrador- and golden ... | 2012 | 22739207 |
| fungal food choices of dermatophagoides farinae affect indoor fungi selection and dispersal. | house dust mite (hdm) feces and molds are the main allergens involved in allergic asthma. differences exist between the housing fungal biome of allergic patients and standard or unhealthy housing. house dust mite (hdm) feed off spores and transport them on their bodies, but do they have fungal food preferences? we observed dermatophagoïdes farinae in vitro with 16 mold menus and repeated the experiment 10 times. this observation led us to define alternaria alternata, cladosporium sphaerospermum, ... | 2013 | 22774849 |
| [allergens and their relationships to childhood bronchial asthma in the jiading district of shanghai]. | to study allergens and their relationship to the occurrence of childhood bronchial asthma in the jiading district of shanghai. | 2012 | 22809606 |
| winter season temperature drops and sulfur dioxide levels affect on exacerbation of refractory asthma in south korea: a time-trend controlled case-crossover study using soonchunhyang asthma cohort data. | according to the american thoracic society, approximately 5% of all asthmatics have refractory asthma (ra); these patients fail to recover lost lung function even after long-term treatment with high doses of medications. | 2012 | 22812434 |
| essential oil components from asarum sieboldii miquel are toxic to the house dust mite dermatophagoides farinae. | in our effort to develop novel plant-derived acaricides, we examined the contact and fumigant toxicity of asarum heterotropoides (asarum sieboldii miquel) essential oil constituents to the house dust mite dermatophagoides farinae (acari: pyroglyphidae). ten constituents, including methyl eugenol (relative amount 42.18 %), were identified by gas chromatography-mass spectroscopy (gc-ms) in the a. sieboldii miq. essential oil. in contact toxicity tests, methyl eugenol (4.2 μg/cm(2), 24 h ld50) was ... | 2012 | 22833176 |
| oral curcumin supplementation in patients with atopic asthma. | oral curcumin is recognized to have anti-inflammatory properties and has been used by ancient traditional medicine for centuries to treat a variety of diseases. in vitro studies have confirmed the ability of curcumin to inhibit allergic inflammatory cytokine responses from lymphocytes; however, there are no in vivo studies of curcumin to treat inflammation associated with allergic asthma. this study was designed to determine the effect of oral curcumin supplementation on patients with stable, pe ... | 2011 | 22852117 |
| regulation of dendritic cell functions against harmful respiratory pathogens by a cysteinyl leukotrienes receptor antagonist. | cysteinyl leukotriene receptor antagonist (ltra) is a widely used medicine for asthma. cysteinyl leukotrienes (cyslts) are involved in the regulation of dendritic cell (dc) function. however, the effects of ltra on dc-related antimicrobial immunity against harmful respiratory pathogens remain unknown. the purpose of this study was to examine the effects of ltra administered in vivo on dc function against representative respiratory pathogens in vitro. pulmonary dcs were isolated from four groups ... | 2012 | 22852127 |
| sensitization and allergic histories differ between black and white pregnant women. | racial differences in allergic diseases have been reported, with black subjects suffering disproportionately compared with white subjects, although such studies have been more commonly done in pediatric populations. | 2012 | 22857795 |
| the effect of stimuli on basophil-mediated atopic responses during asthmatic lying-in women and in newborns. | morbidity from allergic diseases is increasing. basophils play a critical role in systemic anaphylaxis and chronic allergic inflammation. the prenatal environment must be regarded as a possible early risk factor for allergic diseases in children. our objective was to determine if basophils harvested from neonates genetically predisposed to atopic disease had different levels of cd63 expression and il-4 release properties in response to various stimuli (peptidoglycan, dermatophagoides farinae, hy ... | 2012 | 22894778 |
| [efficacy of specific sublingual immunotherapy with dermatophagoides farinae drops in the treatment of cough variant asthma in children]. | to study the efficacy and safety of specific sublingual immunotherapy with dermatophagoides farinae drops in the treatment of cough variant asthma in children. | 2012 | 22898278 |
| racial disparities in allergic outcomes in african americans emerge as early as age 2 years. | racial disparities in allergic disease outcomes have been reported with african americans suffering disproportionately compared to white individuals. | 2012 | 22909162 |
| indoor mite allergen levels, specific ige prevalence and ige cross-inhibition pattern among asthmatic children in haikou, southern china. | haikou locates in tropical island with unique mite propagation. the aim of this stuy is to determine mite allergens levels in haikou, and to investigate the prevalence of mite specific ige-sensitization and ige cross-reactivity between house dust mites. | 2012 | 22932181 |
| efficacy and safety of sublingual immunotherapy in asian children. | sublingual immunotherapy is currently accepted as a suitable alternative to subcutaneous immunotherapy because of its easy and painless administration and improved safety. many clinical trials have demonstrated that sublingual immunotherapy is an effective and safe treatment for pollen or mite allergic rhinitis. however, there have been very few studies overall on children with allergic rhinitis who are sensitized to house-dust mites in asia. the purpose of the present study was to investigate t ... | 2012 | 22959336 |
| crystal structure of der f 7, a dust mite allergen from dermatophagoides farinae. | der f 7 is the group 7 allergen from the dust mite dermatophagoides farinae, homologous to the major allergen der p 7 from d. pteronyssinus. monoclonal antibody that bind to residues leu48 and phe50 was found to inhibit ige binding to residue asp159, which is important for the cross-reactivity between der f 7 and der p 7. | 2012 | 22970319 |
| topical application of an ethanol extract prepared from illicium verum suppresses atopic dermatitis in nc/nga mice. | illicium verum is a traditional herbal medicine with anti-inflammatory properties used in asia. however, its usefulness in the treatment of allergic diseases remains unclear. this study evaluated the anti-inflammatory and antiallergic effects of i. verum extract (ive) in a mouse model of atopic dermatitis. | 2012 | 22971899 |
| cysteinyl leukotriene 2 receptor on dendritic cells negatively regulates ligand-dependent allergic pulmonary inflammation. | cysteinyl leukotrienes (cys-lts) can mediate th2 immunity to the house dust mite, dermatophagoides farinae, via the type 1 receptor cyslt(1)r on dendritic cells (dcs). however, the role of the homologous type 2 receptor cyslt(2)r in th2 immunity is unknown. d. farinae sensitization and challenge of cyslt(2)r-deficient mice showed a marked augmentation of eosinophilic pulmonary inflammation, serum ige, and th2 cytokines. wild-type (wt) mice sensitized by adoptive transfer of d. farinae-pulsed cys ... | 2012 | 23002438 |
| [therapeutic approach to mite-induced intractable dermatitis using novel immunomodulator fty720 (fingolimod) in combination with betamethasone ointment in nc/nga mice]. | the increasing incidence and prevalence of atopic dermatitis (ad) have led to a requirement for new means to treat the disease. we investigated the therapeutic efficacy of the novel immunomodulator fty720 (fingolimod), alone and in combination with betamethasone valerate ointment, in the nc/nga mouse model of mite-induced intractable dermatitis. | 2012 | 23007332 |
| efficacy and safety of a once-daily sublingual immunotherapy without escalation regimen in house dust mite-induced allergic rhinitis. | the conventional escalation regimen for sublingual immunotherapy (slit) in patients with allergic rhinitis has been proven to be safe and successful in reducing allergic symptoms. however, few studies compared the efficacy and safety between a conventional escalation regimen for slit and once-daily slit. the aim of the present study was to compare the efficacy and safety of once-daily slit without escalation (slitse) to conventional escalation therapy (slitwe). | 2013 | 23044892 |
| sensitization rates of airborne pollen and mold in children. | aeroallergens are important causative factors of allergic diseases. previous studies on aeroallergen sensitization rates investigated patients groups that had visited pediatric allergy clinics. in contrast, we investigated sensitization rates in a general population group of elementary school to teenage students in incheon, jeju, and ulsan. | 2012 | 23049589 |
| validation of a novel epicutaneous delivery system for patch testing of house dust mite-hypersensitive dogs. | patch tests with allergens are used for the evaluation of cellular hypersensitivity to food and environmental allergens in dogs and humans with atopic dermatitis. viaskin is a novel allergen epicutaneous delivery system that enhances epidermal allergen capture by immune cells. | 2012 | 23050930 |
| structural biology of mite allergens. | mite allergens contribute to a significant proportion of human allergic symptoms, including asthma and rhinitis. the development of therapies to treat and prevent these symptoms depends largely on our understanding of the properties of these allergens. much effort has been devoted to determining the structure and organization of mite allergens, particularly of the house dust mites, toward understanding their activities and how they elicit immunological responses in humans. here, we review the st ... | 2013 | 23054022 |
| population growth and allergen accumulation of dermatophagoides farinae cultured at 20 and 25 °c. | house dust mites are cultured to obtain mite allergen material to produce allergen extracts (vaccines) for diagnostic tests, immunotherapy, and research purposes. research laboratories and manufacturers have their own culturing protocols to grow these mites and these may vary between manufacturers and between research laboratories. the temperature at which mites are cultured may influence the allergen composition, allergen ratio of der 1: der 2 and endotoxin levels in the extracts produced from ... | 2013 | 23070476 |
| establishment of two novel elisa methods for dermatophagoides farinae-specific ige detection with recombinant group 2 allergen. | dermatophagoides farinae, or the american house dust mite, is a common cause of allergy and asthma. current tests for sensitization to d. farinae include an indirect enzyme-linked immunosorbent assay (elisa) method for specific ige detection, which, while clinically useful, is time-consuming and has low sensitivity since it uses crude mite extracts. we developed two new elisa methods to detect the group 2 allergen from d. farinae (der f 2) and the der f 2-specific ige in sera of patients with as ... | 2012 | 23090735 |
| [clinical significance of skin prick test for inhalant allergens in 3085 children with allergic diseases]. | to investigate the main inhalant allergens and their distribution patterns in children with allergic diseases from xi'an and the surrounding area and to provide evidence for the prevention and treatment of allergic diseases in children. | 2012 | 23092566 |
| specific immunoglobulin e antibodies to saprophytic yeasts in sera of atopic patients allergic to house dust mites. | atopic dermatitis (ad) is a complex disease caused by genetic and environmental interactions. ad impairs skin barrier function, enabling microorganisms to penetrate and interact with the immune system. | 2012 | 23101185 |
| contact and fumigant toxicity of pinus densiflora needle hydrodistillate constituents and related compounds and efficacy of spray formulations containing the oil to dermatophagoides farinae. | the toxicity of red pine needle hydrodistillate (rpn-hd), 19 rpn-hd constituents and another 12 structurally related compounds and the control efficacy of four experimental spray formulations containing rpn-hd (0.5. 1, 2 and 3% sprays) to adult dermatophagoides farinae were evaluated. | 2013 | 23109302 |
| house dust mite allergy in korea: the most important inhalant allergen in current and future. | the house-dust mite (hdm), commonly found in human dwellings, is an important source of inhalant and contact allergens. in this report, the importance of hdm allergy in korea and the characteristics of allergens from dust mite are reviewed with an emphasis on investigations performed in korea. in korea, dermatophagoides farinae is the dominant species of hdm, followed by d. pteronyssinus. tyrophagus putrescentiae is also found in korea, but its role in respiratory allergic disease in korea is co ... | 2012 | 23115727 |
| standardization of house dust mite extracts in korea. | house dust mites are the most important cause of respiratory allergy in korea. standardization of allergen extracts is essential for improving diagnostics and immunotherapeutics. this study was undertaken to evaluate the allergenicity of standardized house dust mite allergen extracts from korean house dust mite isolates. | 2012 | 23115731 |
| the toxic effect of chitosan/metal-impregnated textile to synanthropic mites. | plasma treatment enables effective binding of chitosan film to textile fibres. heavy metal ions such as ag(+) adsorbed onto the chitosan coating are known to enhance toxicity to microorganisms. the acaricidal effect of chitosan and chitosan/metal adducts with ag(+) , zn(2+) and cu(2+) was tested in laboratory experiments. tested species acarus siro, dermatophagoides farinae, d. pteronyssinus and tyrophagus putrescentiae are allergen producers and important pests in house dust, stored food and fe ... | 2013 | 23135827 |
| dermatophagoides farinae house dust mite allergen challenges reduce stratum corneum ceramides in an experimental dog model of acute atopic dermatitis. | ceramides are essential stratum corneum (sc) lipids and they play a pivotal role in maintaining effective cutaneous barrier function. | 2012 | 23140315 |
| [correlation of serum eosinophil cationic protein with the severity of allergic rhinitis in childhood]. | to investigate the relationships between the severity of childhood allergic rhinitis (ar) and the peripheral blood eosinophil count, serum eosinophil cationic protein (ecp), total ige (tige), and allergen-specific ige (sige) levels. | 2012 | 23141391 |
| [investigation of skin prick test on 2707 patients with allergic rhinitis in wuhan area]. | to investigate the distribution of common allergens in patients with allergic rhinitis (ar) from 2006 to 2010 in wuhan area, and provide the objective evidence for the prevention and treatment of ar. | 2012 | 23141402 |
| multiplex pcr for identifying common dust mites species (dermatophagoides pteronyssinus, dermatophagoides farinae and blomia tropicalis). | dust mites are known to be an important source of inhalant allergens causing allergic rhinitis and asthma worldwide. the sizes of dust mite populations in patients' houses are useful to monitor the risk of allergen exposure. however, mite identification using the conventional microscopic technique requires specific expertise and is time consuming; therefore a molecular technique has been developed in order to solve these drawbacks. | 2012 | 23156853 |
| contact and fumigant toxicities of 3-methylphenol isolated from ostericum koreanum and its derivatives against house dust mites. | the acaricidal activities of an active constituent derived from ostericum koreanum roots and its derivatives were determined using fumigant and direct-contact toxicity bioassays against dermatophagoides farinae and dermatophagoides pteronyssinus . this was compared with that of a commercial acaricide (benzyl benzoate). in the fumigant toxicity bioassay, 4-chloro-6-isopropyl-3-methylphenol (0.29 μg/cm(2)) was 37.17 times more effective than benzyl benzoate (10.78 μg/cm(2)) against d. farinae, fol ... | 2012 | 23194135 |
| effects of catalpa ovata stem bark on atopic dermatitis-like skin lesions in nc/nga mice. | the stem bark of catalpa ovata has been used as a traditional herbal medicine for the treatment of various inflammatory diseases such as itching and scabies. | 2013 | 23195129 |
| correlation of symptoms with total ige and specific ige levels in patients presenting with allergic rhinitis. | the objective of this study was to investigate the correlation of symptoms in patients with presumed allergic rhinitis on the basis of their medical history and physical examination with the levels of total immunoglobulin e (ige) and specific ige, and to question the necessity of these tests in diagnosis. | 2013 | 23197073 |
| mite hypersensitivity in patients with rhinitis and rhinosinusitis living in a tropical environment. | rhinitis and rhinosinusitis are major concerns in public health. mites are important aetiological agents in the tropics. the present study investigated the in vivo response to mite allergens in patients with rhinitis and rhinosinusitis. | 2014 | 23253681 |
| incrimination of blomia tropicalis as a potent allergen in house dust and its role in allergic asthma in kolkata metropolis, india. | the increasing trend in allergic diseases has become obvious in the present day, especially in developing countries like india, because of many factors such as change in ambient air quality, increased air pollution, metamorphic change in living habits and lifestyle, and climate.1 mites present in house dust represent a major source of allergens, resulting in different allergic manifestations all over the world, and hypersensitivity to these dust mites may play a pivotal role in pathogenesis of s ... | 2010 | 23268430 |
| [efficacy and safety of sublingual immunotherapy with house dust mite extract in poly allergen sensitized children with allergic rhinitis]. | to compare the efficacy of sublingual immunotherapy (slit) with standardized house dust mite extract in mono sensitized and polysensitized children with allergic rhinitis. | 2012 | 23272490 |
| domestic mite antigens in floor and airborne dust at workplaces in comparison to living areas: a new immunoassay to assess personal airborne allergen exposure. | allergens produced by domestic mites (dm) are among the most common allergic sensitizers and risk factors for asthma. to compare exposure levels between workplaces and living areas a new assay able to measure airborne dm antigen concentrations was developed. | 2012 | 23285240 |
| immunization of rabbits with nematode ascaris lumbricoides antigens induces antibodies cross-reactive to house dust mite dermatophagoides farinae antigens. | there are controversial reports on the relationship between helminthic infection and allergic diseases. although ige cross-reactivity between nematode ascaris antigens and house dust-mite allergens in allergic patients have been reported, whether ascaris or the mite is the primary sensitizer remains unknown. here we found that immunization of naïve animals with ascaris lumbricoides (al) antigens induced production of antibodies cross-reactive to mite antigens from dermatophagoides farinae (df). ... | 2013 | 23291773 |
| the effect of pneumococcal polysaccharide vaccine in a mouse model of allergic rhinitis. | this study aimed to determine if pneumococcal polysaccharide vaccine (ppv) could suppress allergic inflammation in an allergic rhinitis mouse model and to explore whether differences exist regarding the effect of ppv according to timing of administration. | 2013 | 23314157 |
| differential effects of dexamethasone and itraconazole on aspergillus fumigatus-exacerbated allergic airway inflammation in a murine model of mite-sensitized asthma. | fungal exposure is associated with particularly severe asthma. nevertheless, the effects of anti-fungal treatments on fungus-exacerbated asthma need to be determined. | 2013 | 23327882 |
| [allergen analysis on patients with allergic rhinitis in lanzhou]. | to investigate the effective clinical diagnosis and treatment for allergic rhinitis (ar) by examining the allergens and dietary habits of the patients. | 2012 | 23328046 |
| bronchial allergen challenges in children - safety and predictors. | in allergic asthma, the diagnosis of house dust mite (hdm) allergy is mainly based on the patient's history, allergy testing by the skin prick test (spt) or the levels of allergen-specific ige. we retrospectively analysed data from 350 bronchial provocations with hdm and related it to the following parameters: specific ige, bronchial hyperresponsiveness (bhr) to methacholine testing (mct) and exhaled no (eno). | 2013 | 23331526 |
| house dust mite sublingual immunotherapy: a double-blind, placebo-controlled study in elderly patients with allergic rhinitis. | immunotherapy in elderly patients is controversial, and there is still no evidence supporting this treatment's safety and efficacy in this population. this study was performed to evaluate the safety and efficacy of specific sublingual immunotherapy for house dust mite (hdm) allergens in patients over 60 years of age with allergic rhinitis and a confirmed allergy to hdm. | 2013 | 23331565 |
| production of a chimeric allergen derived from the major allergen group 1 of house dust mite species in nicotiana benthamiana. | plants are widely accepted as a general platform for the large-scale production of recombinant proteins, which has been demonstrated by the successful expression of various exogenous proteins. using plants as a bioreactor for mass production of target proteins for vaccines is thought to show the most potential. this study explores whether a chimeric allergen r8, derived from the major allergen group 1 of house dust mites species (dermatophagoides farinae and dermatophagoides pteronyssinus), is e ... | 2013 | 23354320 |
| the skin prick test - european standards. | skin prick testing is an essential test procedure to confirm sensitization in ige-mediated allergic disease in subjects with rhinoconjunctivitis, asthma, urticaria, anapylaxis, atopic eczema and food and drug allergy. this manuscript reviews the available evidence including medline and embase searches, abstracts of international allergy meetings and position papers from the world allergy literature. the recommended method of prick testing includes the appropriate use of specific allergen extract ... | 2013 | 23369181 |
| allergic sensitization frequency and wheezing differences in early life between black and white children. | asthma is more common in black children than in white children. allergic sensitization has been shown to be associated with increased likelihood of asthma. this study was designed to determine whether there are racial differences in the allergens to which children are sensitized in the detroit metropolitan area and determine whether sensitization was associated with wheeze outcomes. pregnant women were recruited for the wayne county health, environment, allergy, and asthma longitudinal study bir ... | 2012 | 23394507 |
| ykl-40 in induced sputum after allergen bronchial provocation in atopic asthma. | serum chitinase-like proteins such as ykl-40 in asthmatic patients are known to positively correlate with disease severity but controversy remains regarding their role. the allergen bronchial provocation test (abpt) can induce allergic airway inflammation in individuals with atopic asthma. | 2012 | 23397672 |
| serum eosinophil cationic protein level in chinese subjects with nonallergic and local allergic rhinitis and its relation to the severity of disease. | nonallergic rhinitis (nar) is a common disease, and local allergic rhinitis (lar) is a newly described entity that is called "entopy" in recent years. however, the etiology and incidence of nar and lar are uncertain. this study evaluates the incidence of lar in chinese subjects and serum eosinophil cationic protein (ecp) levels in patients with nar and lar and its relationship with symptom scores. | 2013 | 23406588 |
| the development of allergic rhinitis in children previously diagnosed as nonallergic rhinitis. | nonallergic rhinitis (nar) is characterized by nasal symptoms similar to allergic rhinitis (ar) without an ige-mediated immune response. limited data are available on the natural history of nar in its progression toward ar, particularly in children. this study evaluates the development of ar in children who were previously diagnosed with nar. | 2013 | 23406600 |
| comparison of antiallergic effects of pneumococcal conjugate vaccine and pneumococcal polysaccharide vaccine in a murine model of allergic rhinitis. | pneumococcal vaccines have been widely used, and streptococcus pneumoniae has been suggested to be an effective therapeutic agent in allergic disease. | 2013 | 23417574 |
| species diversity of house dust mites in beijing, china. | even though house dust mites are one of the most important allergens, there have been few studies in china for their identification and diversity. in this study, we reported that dermatophagoides siboney was found for the first time in beijing, china, in a temperate zone and it was also the first reported in asia. this survey of mite prevalence was carried out in several districts of beijing, a city of thirty million people. house dust samples were collected from 38 homes of mite-allergic patien ... | 2013 | 23427649 |
| enzymatic activity of allergenic house dust and storage mite extracts. | proteases are involved in the pathogenicity of allergy, increasing epithelial permeability and acting as adjuvants. enzymatic activity is therefore important for the allergenicity of an extract and also affects its stability and safety. however, the enzymatic activity of extracts is not usually evaluated. the objective of this study was to evaluate the enzymatic activity of the most allergenic mite extracts and to investigate their allergenic properties. extracts from nine allergenic mite specie ... | 2013 | 23427664 |
| the group 10 allergen of dermatophagoides farinae (acari: pyroglyphidae): cdna cloning, sequence analysis, and expression in escherichia coli bl21. | dermatophagoides farinae hughes, american house dust mite, is highly allergenic, producing symptoms in people worldwide. identifying and cloning the allergens in this species may enable better diagnostic and therapeutic approaches. here, we cloned, sequenced, and expressed the full-length cdna encoding d. farinae group 10 allergen (der f 10) isolated from dust mites in china. bioinformatic analysis indicated that the 888 bp sequence encoded a cytoskeleton protein 295 amino acids long, with a mol ... | 2013 | 23427671 |
| mite fauna and mite antigen detection in house dust found in residential areas in los baños, laguna, philippines. | dust mites are a medically important group of animals commonly found in carpets and mattresses in houses. antigens in their feces cause allergic reactions such as asthma and contact dermatitis. dust samples were vacuum-collected in a special collecting bag from a one square meter area of living room floors of 100 randomly sampled houses in los baños, laguna, philippines for one minute. chromato-immunoassay elisa (mitey checker) was used to detect mite antigenicity. twenty-three species of mites ... | 2012 | 23431817 |
| investigation of the effect of probiotic exposure on filaggrin expression in an experimental model of canine atopic dermatitis. | atopic dermatitis (ad) results from complex interactions between an impaired skin barrier and immunological stimulation. filaggrin is a key protein for the skin barrier, and its expression is decreased in subsets of atopic dogs and can be modified by inflammation; thus, immunomodulatory approaches may alter its expression. probiotics have been explored for the prevention and treatment of allergies, owing to their immunomodulatory properties; however, it is currently unknown whether they can modu ... | 2013 | 23432387 |
| [house dust mite allergy--living with the invisible roommates]. | house dust mites are the most common sources of allergic sensitization, primarily responsible for the occurrence of various clinical forms of respiratory and skin allergies, but also of certain forms of food allergy. there are many various mite species, of which only a small number are constantly or occasionally found in house dust samples. mites from pyroglyphidae family, dermatophagoides pteronyssinus and dermatophagoides farinae are most frequently responsible for sensitization of susceptible ... | 2012 | 23437635 |
| [analysis on the allergens in allergic rhinitis patients in changzhou district of jiangsu]. | to investigate the distribution of positive allergens in patients with allergic rhinitis in changzhou. | 2012 | 23451473 |
| dermatophagoides farinae allergens diversity identification by proteomics. | the most important indoor allergens for humans are house dust mites (hdm). fourteen dermatophagoides farinae allergens (der f 1-3, 6, 7, 10, 11, 13-18, and 22) are reported although more than 30 allergens have been estimated in d. farinae. seventeen allergens belonging to 12 different groups were identified by a procedure of proteomics combined with two-dimensional immunoblotting from d. farina extracts. their sequences were determined by edman degradation, mass spectrometry analysis, and cdna c ... | 2013 | 23481662 |
| [study of tacrolimus intranasal treatment for allergic asthma in mice]. | to explore the efficacy of intranasal treatment by immunosuppressant tacrolimus for allergic asthma and its mechanism in mice. | 2012 | 23484272 |
| oleanolic acid acetate inhibits atopic dermatitis and allergic contact dermatitis in a murine model. | atopic dermatitis (ad) and allergic contact dermatitis (acd) are common allergic and inflammatory skin diseases caused by a combination of eczema, scratching, pruritus, and cutaneous sensitization with allergens. this paper examines whether oleanolic acid acetate (oaa) modulates ad and acd symptoms by using an existing ad model based on the repeated local exposure of mite extract (dermatophagoides farinae extract, dfe) and 2,4-dinitrochlorobenzene to the ears of balb/c mice. in addition, the pap ... | 2013 | 23499868 |
| inhibitory effects of polysaccharide-rich extract of phragmites rhizoma on atopic dermatitis-like skin lesions in nc/nga mice. | phragmites rhizoma was reported to have anti-oxidative and free radical scavenging activity. it also has been traditionally used to suppress inflammation. in the present study, we aimed to evaluate the topical effects of the polysaccharide-rich extract of p. rhizoma (pep) on atopic dermatitis. | 2013 | 23517777 |
| involvement of nuclear factor of activated t cells in granulocyte-macrophage colony-stimulating factor production in canine keratinocytes stimulated with a cysteine protease. | a previous study demonstrated that the cysteine protease of dermatophagoides farinae induced production of granulocyte-macrophage colony-stimulating factor (gm-csf) in a canine epidermal keratinocyte progenitor cell line (cpek); however, the molecular mechanism has not been elucidated. | 2013 | 23530471 |
| sublingual immunotherapy for experimental allergic conjunctivitis in a murine model induced by dermatophagoides farinae allergen. | sublingual immunotherapy (slit) is a clinically effective treatment in allergic conjunctivitis (ac); however, the mechanism of the underlying pharmacodynamics remains unclear. here, we investigate the efficacy and the mechanism of a sublingually administered dermatophagoides farinae (der f) vaccine in a murine ac model. | 2013 | 23548949 |
| house dust mite allergen der f 2 induces interleukin-13 expression by activating the pi3k/akt pathway. | house dust mites (hdms) are a common cause of allergic asthma. the group 2 allergen from dermatophagoides farinae, der f 2, is one of the major hdm allergens. elevated der f 2 immunoglobulin e (ige) levels are observed in most of the allergic patients. interleukin-13 (il-13), a gene associated with asthma pathology, was induced by der f 2 in beas-2b human airway epithelial cells; however, the signaling pathways associated with der f 2 are not fully understood. in this study, we identified a role ... | 2013 | 23564227 |
| acaricidal activity of cymbopogon citratus and azadirachta indica against house dust mites. | to examine the acaricidal effects of the essential oil of cymbopogon citratus leaf extract (lemongrass) and ethanolic azadirachta indica leaf extract (neem) against house dust mites dermatophagoides farinae (d. farinae) and dermatophagoides pteronyssinus (d. pteronyssinus). | 2011 | 23569794 |
| effect of a commercial air ionizer on dust mites dermatophagoides pteronyssinus and dermatophagoides farinae (acari: pyroglyphidae) in the laboratory. | to investigate the short and long term efficacy of a commercial air ionizer in killing dermatophagoides pteronyssinus (d. pteronyssinus) and dermatophagoides farinae (d. farinae) mites. | 2012 | 23569888 |
| effect of germicidal uv-c light(254 nm) on eggs and adult of house dustmites, dermatophagoides pteronyssinus and dermatophagoides farinae (astigmata: pyroglyhidae). | to examined the immediate and 24 hours post- irradiation germicidal effects of uv-c lamp on eggs and adults of house dust mites dermatophagoides pteronyssinus (d. pteronyssinus) and dermatophagoides farinae (d. farinae). | 2012 | 23569994 |
| impact of atopy on asthma and allergic rhinitis in the cohort for reality and evolution of adult asthma in korea. | atopy is an important cause of asthma. few data on the prevalence of atopy or comparisons with clinical characteristics of asthma in korean patients have been published. we evaluated the effects of atopy on clinical profiles and airway inflammation in korean asthmatics. | 2012 | 23638312 |
| assessment of total/specific ige levels against 7 inhalant allergens in children aged 3 to 6 years in seoul, korea. | childhood allergies are a serious problem, as they may lead to lifetime chronic disease. determination of total and specific ige levels is known to be a diagnostic tool for allergic sensitization; however, ige levels are affected by various factors, such as age, sex, ethnicity, and geographic area. thus, we evaluated the distribution of total and specific serum ige levels against seven inhalant allergens in preschool children and examined their association with allergic diseases in seoul, korea. | 2013 | 23638315 |
| proteins and endotoxin in house dust mite extracts modulate cytokine secretion and gene expression by dermal fibroblasts. | house dust mite extracts used for diagnostic tests and immunotherapy contain bioreactive molecules including proteins and endotoxin. these extracts can influence the cytokine secretion and adhesion molecule expression by cells in the skin and lung airways. the aim of this study was to determine the role of proteins and endotoxin in mite extracts in modulating gene expression and cytokine secretion by human dermal fibroblasts. cultured normal human dermal fibroblasts were stimulated with whole mi ... | 2013 | 23640713 |
| group v secretory phospholipase a2 is involved in macrophage activation and is sufficient for macrophage effector functions in allergic pulmonary inflammation. | we reported that pla2g5-null mice lacking group v secretory phospholipase a2 (gv-spla2) showed reduced eosinophilic pulmonary inflammation and th2 cytokine generation when challenged with an extract from house dust mite dermatophagoides farinae, compared with wild-type (wt) controls. adoptive transfer studies suggested that gv-spla2 in dendritic cells was necessary for sensitization of pla2g5-null mice, but was not sufficient to induce the effector phase of pulmonary inflammation. in this study, ... | 2013 | 23650617 |