Publications
| Title | Abstract | Year Filter | PMID(sorted ascending) Filter |
|---|
| [complex sanitary-microbiological criteria of evaluating the quality of water in increasing anthropogenic load]. | it has been established with the help of sanitary-hygienic, microbiological and statistical methods, that the increasing ++anthropogenic stress on water reservoirs induce quantitative and qualitative changes of water biocenosis under the conditions of intensive use of water reservoirs for economic purposes. it can produce unfavourable health effects on the population, as well as on the equilibrium of the local ecological microsystems. the necessity has been substantiated of the use of complex sa ... | 1991 | 1906038 |
| [the infectivity of enterococcus faecalis in experimental urinary tract infection in mice: ii]. | the infectivity of enterococcus faecalis was compared with that of escherichia coli in the urinary tract in mice. the infectivity of e. faecalis in normal mice was found to be equal to that of e. coli. the mice previously treated with cyclophosphamide, carrageenin or alloxan as the immunosuppressive drug, and restricted water supply, were more susceptible to enterococcal infection than non-treated ones. these data were confirmed with histological examinations. e. faecalis is a pathogenic organis ... | 1991 | 1906513 |
| [enterococcus faecalis bacteremia. study of 113 cases]. | 1991 | 1906566 | |
| experimental bacterial prostatitis in rats. | experimental acute bacterial prostatitis in rats was induced by four different routes of bacterial inoculation. the most simple and reproducible method of producing bacterial prostatitis was to instil the bacterial suspension into the prostatic urethra after the administration of an appropriate antibiotic to prevent associated pyelonephritis. | 1991 | 1906656 |
| in vitro activities of sparfloxacin, tosufloxacin, ciprofloxacin, and fleroxacin. | the in vitro activity of sparfloxacin was compared with those of tosufloxacin, ciprofloxacin, and fleroxacin against 730 bacterial isolates representing 49 different species. sparfloxacin and ciprofloxacin had similar spectra of activity, but sparfloxacin was less active against pseudomonas aeruginosa and more active against many gram-positive cocci and anaerobic bacteria. tosufloxacin mics were generally 8- to 16-fold lower than those for sparfloxacin or ciprofloxacin. all four fluoroquinolones ... | 1991 | 1906696 |
| synergistic post-antibiotic effect of amikacin and beta-lactam antibiotics on enterococcus faecalis. | the in-vitro post-antibiotic effect (pae) of amikacin alone and in combination with ceftazidime, ceftriaxone and piperacillin was studied for two strains of enterococcus faecalis using a bioluminescent assay of bacterial atp. the two strains of e. faecalis were resistant to amikacin, ceftazidime and ceftriaxone but sensitive to piperacillin. the bacterial cultures were incubated with the beta-lactam antibiotics for 1 h and concentrations of amikacin between 2-64 mg/l were then added. thereafter, ... | 1991 | 1906865 |
| enterococcal meningitis in an hiv positive haemophilic patient. | a 25 year old, human immunodeficiency virus (hiv) seropositive, severe haemophilic patient was treated for suspected pneumocystis carinii infection with high dose intravenous cotrimoxazole and subsequently with prednisolone. when he improved he was discharged on oral treatment only to return two days later, extremely unwell, with headaches, fever, sweats, tachycardia and hypotension. a lumbar puncture showed modest neutrophil pleocytosis but despite empirical antibiotic treatment with intravenou ... | 1991 | 1906898 |
| distribution and purification of aspartate racemase in lactic acid bacteria. | the distribution of aspartate racemase (ec 5.1.1.13) in various kinds of bacteria demonstrated that the enzyme occurs in lactic acid bacteria, such as streptococcus species and lactobacillus species. the enzyme from streptococcus thermophilus iam10064 was more thermostable than that from streptococcus lactis iam1198 which contained the enzyme most abundantly among the lactic acid bacteria we examined here. we purified the enzyme about 3400-fold to homogeneity from cell-free extract of s. thermop ... | 1991 | 1907199 |
| detection of enterococcal high-level aminoglycoside resistance with microscan freeze-dried panels containing newly modified medium and vitek gram-positive susceptibility cards. | both conventional and modified microscan type 5 panels and vitek gram-positive susceptibility cards were compared with agar dilution screen plates for their abilities to detect high-level resistance to gentamicin and streptomycin in 235 enterococcal isolates, including 167 enterococcus faecalis and 63 e. faecium isolates. the modified type 5 panels contained dextrose-phosphate broth instead of mueller-hinton broth in their high-level-resistance screen wells. the sensitivities for detection of ge ... | 1991 | 1907609 |
| comparison of the new microscan pos mic type 6 panel and ams-vitek gram positive susceptibility card (gps-ta) for detection of high-level aminoglycoside resistance in enterococcus species. | we compared the microscan pos mic type 6 panel and ams-vitek gram positive susceptibility card (gps-ta) to agar dilution screen plates for the detection of high-level aminoglycoside resistance in 182 enterococcal isolates. the specificity of the two commercial systems was 100%, with the exception of one susceptible isolate found to be streptomycin resistant by the vitek system. the microscan and vitek systems had comparable sensitivities for the detection of gentamicin resistance (90 and 95% res ... | 1991 | 1907610 |
| kinetics of the extracellular proteinase production by the proteolytic biovar of enterococcus faecalis in complex media and skim milk. | 1991 | 1907715 | |
| antibiotic resistance among enterococci: current problems and management strategies. | 1991 | 1907832 | |
| streptococcus bovis septicaemia associated with uncomplicated colonic carcinoma. | 1991 | 1908347 | |
| activity of antiseptics against biofilms of mixed bacterial species growing on silicone surfaces. | as part of a programme to establish the relative merits of antiseptics that are used as bladder instillations to control urinary tract infections in patients with indwelling catheters, the activity of five such formulations were tested against dense (10(9) cfu/cm2) mixed biofilms composed of citrobacter diversus, pseudomonas aeruginosa and enterococcus faecalis growing on silicone discs. all three species were resistant to chlorhexidine (200 mg/l) and povidone-iodine (1% v/v) in the biofilm mode ... | 1991 | 1908382 |
| two lipoyl domains in the dihydrolipoamide acetyltransferase chain of the pyruvate dehydrogenase multienzyme complex of streptococcus faecalis. | a fragment of dna incorporating the gene, pdhc, that encodes the dihydrolipoamide acetyltransferase (e2) chain of the pyruvate dehydrogenase multienzyme complex of streptococcus faecalis was cloned and a dna sequence of 2360 bp was determined. the pdhc gene (1620 bp) corresponds to an e2 chain of 539 amino acid residues, mr 56,466, comprising two lipoyl domains, a peripheral subunit-binding domain and an acetyltransferase domain, linked together by regions of polypeptide chain rich in alanine, p ... | 1991 | 1908789 |
| structural relationship between the vancomycin resistance protein vanh and 2-hydroxycarboxylic acid dehydrogenases. | sequencing upstream from the vana gene of enterococcal plasmid pip816 that confers vm resistance revealed the presence of an orf which could code for a protein of 322 aa designated vanh. extensive aa similarity was detected between vanh and 2-hydroxycarboxylic acid dehydrogenase. we discuss possible roles for vanh in the synthesis of a novel type of peptidoglycan precursors with lower affinity for vm. | 1991 | 1908809 |
| relapsing native-valve enterococcal endocarditis: a unique cure with oral ciprofloxacin combination drug therapy. | enterococcal endocarditis is the third most common presentation in native valves, and it is the most refractory. unique among the streptococci, enterococci are relatively resistant to beta-lactam antibiotics requiring a combination aminoglycoside regimen for cure. relapse is common even after apparently adequate therapy and may be seen in up to 25% of cases that involve streptomycin-resistant strains. this problem is magnified by the recent appearance of beta-lactamase-producing strains of s. fa ... | 1991 | 1908863 |
| alterations in oral microflora and pathogenesis of acute oral infections during remission-induction therapy in patients with acute myeloid leukaemia. | to investigate changes in the aerobic and facultatively anaerobic oral microflora during remission-induction chemotherapy in patients with acute myeloid leukaemia, 10 consecutive patients were studied during a period of 28 days. during antineoplastic treatment, the concentration of microorganisms in saliva doubled from day 0 to day 2, presumably as a result of a concurrent 64% decrease in the salivary flow rate. no changes in the relative proportion of individual microorganisms or acquisition of ... | 1991 | 1909053 |
| bacteriologically stressed animal model of new closed catheter drainage system with microbicidal outlet tube. | we have used a catheterized rabbit model to test a newly developed catheter drainage system that incorporates a microbicidal outlet tube. in these tests, this new system was compared with a currently marketed closed drainage system, with daily challenge at the outlet tube using an auxotrophically marked uropathogenic strain of escherichia coli. in the control series (silicone catheter connected to a standard drainage bag via a tamper-evidence seal) the challenge organism developed upstream biofi ... | 1991 | 1909475 |
| cefpirome, alone and in combination with gentamicin for enterococcal pyelonephritis in the rodent model. | the in vitro and in vivo activity of cefpirome (cf) against enterococcus faecalis gk strain was examined. the ratio of minimal inhibitory to bactericidal concentration (mic/mbc) values in microgram/ml were (a) ampicillin 0.8/1.5; (b) gentamicin 2/25; (c) vancomycin, 0.8/50; and (d) cf, 8/32. a time-kill study using 10(7) organisms per milliliter showed a drop of 3 logs10 at 4 hr in the tube containing cefpirome (10 micrograms/ml) as well as the tube containing cefpirome (5 micrograms/ml) plus ge ... | 1991 | 1909613 |
| bactericidal effect of penicillin, ampicillin, and amoxicillin alone and in combination with tobramycin against enterococcus faecalis as determined by kill-kinetic studies. | fifteen strains of enterococcus faecalis, all clinical blood culture isolates from patients with endocarditis, were studied by kill-kinetic experiments using penicillin g, ampicillin and amoxicillin alone and in combination with tobramycin. the median minimal inhibitory concentrations (mic), were penicillin 4 mg/l, ampicillin 2 mg/l, amoxicillin 2 mg/l and tobramycin 32 mg/l. equipotent doses of the antibiotics (1/2 x mic, 1 x mic and 4 x mic) were used in the kill-kinetic studies. synergism was ... | 1991 | 1909688 |
| composition of the enterococcal and streptococcal intestinal flora of poultry. | identification to species level showed that enterococcus faecalis and ent. faecium largely dominated the enterococcal and streptococcal gut flora of 1-d-old chicks. enterococcus faecalis was rare in 3- to 5-week-old broilers. two species, ent. faecium and streptococcus alactolyticus, were isolated from nearly all broilers examined. enterococcus hirae and ent. durans were found in the small intestines of this category of poultry. in layers and parent stock of over 12 weeks of age, ent. cecorum do ... | 1991 | 1910033 |
| [enterococcus faecalis bacteremia]. | this study was prompted by the increasing role of e. faecalis in hospital acquired infections, their morbidity and mortality and the development of resistances. the aim of the study was to define the epidemiological features, the predictive factors of bacteremia and the mortality prognosis in a group of patients with e. faecalis bacteremia. | 1991 | 1910132 |
| [group d streptococci and enterococci: identification, sensitivity to antibiotics and a study of the high level resistance to aminosides (charles nicolle hospital in tunis)]. | 197 strains of enterococcus and group d streptococcus were isolated from human material at charles nicolle hospital (tunis) and identified by biochemical tests: 174, enterococcus faecalis, 6 enterococcus faecium, 2 enterococcus durans and 15 streptococcus bovis. the sensitivity to antibiotics was studied: all enterococcus faecium were resistant at least to one antibiotic, 15% of enterococcus faecalis were sensitive for all antibiotics tested the other species were frequently sensitive. high leve ... | 1991 | 1910140 |
| [a case of metastatic enterococcus faecalis endophthalmitis]. | we reported a case of successful treatment of early-stage metastatic endophthalmitis caused by enterococcus faecalis with vitrectomy and lensectomy. the case was a 50-year-old male with poorly controlled diabetes. following t-tube drainage for a necrotic cholecystitis operation, he developed iridocyclitis in both eyes as well as fever. at the time of his first visit to our clinic, his right eye had already lost light perception. his left eye had visual acuity recognizing of hand movement, marked ... | 1991 | 1910253 |
| in vitro studies with bay v 3522, a new oral cephalosporin. | the in vitro activities of bay v 3522, cefaclor, cephalexin, cefuroxime, cefixime, amoxicillin/clavulanate (2:1) and reference penicillins were compared against 314 clinical isolates of gram-positive and gram-negative bacteria and nine strains of escherichia coli that differed in their outer membrane proteins in agar dilution tests with an inoculum of 10(4) cfu/spot. the beta-lactamase stabilities of the cephalosporins were also evaluated by spectrophotometric assay using 21 different beta-lacta ... | 1991 | 1914843 |
| [a case of enterococcus faecalis brain abscess in a patient with suprapharyngeal cancer]. | a 55-year-old male was admitted to our hospital for the treatment of suspected brain abscess on march 18, 1989. the brain ct scan showed low density area with ring enhancement. after admission, both cefminox 2 g/day and clindamycin 500 mg/day were administered intravenously. on march 29, 1989, the patient developed cerebral herniation suddenly. therefore emergency burr hole operation was done. many gram-positive cocci were observed on gram-staining of the aspirated pus. moreover neutrophils with ... | 1991 | 1919105 |
| effect of nacl-induced osmotic stress on intracellular concentrations of glycine betaine and potassium in escherichia coli, enterococcus faecalis, and staphylococci. | staphylococci are more salt tolerant than are enterococci or escherichia coli. they have a more rigid cell wall and higher internal turgor pressure. the mechanisms of nacl-induced osmotic tolerance among these bacteria were examined by determining the generation of osmoprotective activity of cellular extracts and intracellular concentrations of glycine betaine and potassium (k+) in response to graded amounts of nacl. staphylococci as well as e. coli were shown to require choline or glycine betai ... | 1991 | 1919294 |
| control of enterococcus faecalis sex pheromone cad1 elaboration: effects of culture aeration and pad1 plasmid-encoded determinants. | aeration of plasmid-free enterococcus faecalis strains resulted in an 8- to 16-fold decrease in sex pheromone cad1 activity in culture filtrates. levels of two unrelated pheromones, cpd1 and cam373, were unaffected by culture aeration. aeration also resulted in a decrease in the expression of conjugative transfer functions observed in cells containing pad1 trab mutations, verifying a link between trab function and pheromone "shutdown." tests with a series of pad1 mini-plasmids indicated that the ... | 1991 | 1924555 |
| enterococcal bacteremia: to treat or not to treat, a reappraisal. | the treatment of enterococcal bacteremia not associated with endocarditis has been controversial. we retrospectively reviewed 81 episodes of enterococcal bacteremia and categorized them as to their clinical significance, using a strict case definition. of the 81 episodes, 41 met our criteria for clinical significance. mortality was 51% among the 41 patients with clinically significant bacteremia and 50% among the 40 patients with bacteremia of uncertain clinical significance. despite these equiv ... | 1991 | 1925276 |
| [effect of storage on microbiological indicators in oysters]. | 1991 | 1926822 | |
| effect of intraperitoneal administration of oxygen on the course of experimentally induced peritonitis. | over the first 3 days of experimentally induced peritonitis, 40 rabbits were given oxygen intraperitoneally (ip) up to a pressure of 3 to 5 mm hg in the peritoneal cavity at 12-hour intervals. compared with a control group, significant differences were recorded in the mortality rate within the studied 7-day period of peritonitis (p less than 0.05). in 29 rabbits with intraperitoneal administration of oxygen, the size of the area that formed the inner wall of the abscess cavity was significantly ... | 1991 | 1928583 |
| use of corticosterone and ampicillin for treatment of streptococcus faecalis infection in chickens. | chickens were selectively bred for either high-antibody (ha) or low-antibody (la) response to sheep erythrocytes. from 6 to 31 days after streptococcus faecalis challenge exposure, la-line chickens maintained a greater percentage of the prechallenge-exposure body weight and had lower heterophil-to-lymphocyte ratio than did ha-line chickens. the optimal dose of corticosterone (30 mg/kg of feed) was effective in maintaining postchallenge-exposure body weight greater than that of controls. ampicill ... | 1991 | 1928910 |
| antimicrobial susceptibility and molecular epidemiology of beta-lactamase-producing, aminoglycoside-resistant isolates of enterococcus faecalis. | beta-lactamase-producing (bl+), aminoglycoside-resistant (ar) enterococcus faecalis is endemic in our hospital, having caused widespread colonization and infection. suitable therapy for infections caused by these organisms has been problematic. we compared the antimicrobial and bactericidal activities, by broth macrodilution and time-kill methods, of several antibiotics, alone and in combination, against bl+, ar isolates of e. faecalis and determined the transmissibility of antibiotic resistance ... | 1991 | 1929246 |
| bacteremia caused by hemolytic, high-level gentamicin-resistant enterococcus faecalis. | between 1 january 1984 and 31 december 1987, 206 enterococcal blood isolates at the university of wisconsin hospital and clinics were analyzed for high-level aminoglycoside resistance (hereafter high-level aminoglycoside resistance is simply referred to as "resistance") and hemolysin production. of 190 enterococcus faecalis isolates, 68 (35.8%) were resistant to gentamicin. of these 68 strains, 67 (98.5%) contained a gene coding for the bifunctional aminoglycoside-modifying 6'-aminoglycoside ace ... | 1991 | 1929336 |
| tetracycline resistance in peptostreptococcus species. | of 15 peptostreptococcus sp. strains isolated between 1975 and 1984, 13 hybridized with the tet k, tet m, or tet o determinant. a donor peptostreptococcus anaerobius strain carrying the three determinants could transfer tet m to p. anaerobius and fusobacterium nucleatum recipients but not to an enterococcus faecalis recipient, while neither tet k nor tet o was transferred. | 1991 | 1929341 |
| in vitro antibacterial activity of me1207, a new oral cephalosporin. | me1207 is the prodrug of me1206. its in vitro antibacterial activity was compared with that of cefteram, cefpodoxime, cefixime, and cefaclor against various clinical isolates. me1206 was more active than the other cephems tested against staphylococci, streptococci, morganella morganii, pseudomonas cepacia, and flavobacterium meningosepticum and had the most potent activity against haemophilus influenzae and neiserria gonorrhoeae. the drug also showed a wide spectrum of activity against other gra ... | 1991 | 1929344 |
| comparison of 30 microgram and 120 microgram gentamicin disks for the prediction of gentamicin resistance in enterococcus faecalis. | single strain regression analysis was performed on pdm ii medium for e. faecalis with 10, 30 and 120 micrograms gentamicin disks using e. faecalis, strain atcc 29212 as the reference. this method permits the calculation of zone diameters corresponding to different mic values for different disk contents. the lack of discrimination between normal low-level resistant strains and high-level resistance using the 10 micrograms disk was confirmed. however, both the 30 micrograms and 120 micrograms disk ... | 1991 | 1930962 |
| synergy and cumulated killing effect of the penems fce 22101 and fce 25199 in combination with gentamicin against bacteria isolated from septicaemia. | blood isolates of enterococcus faecalis, streptococcus sanguis, staphylococcus aureus, e. coli and klebsiella oxytoca were tested for their synergistic and cumulated killing effect (cke) with the new penems fce 22101 or fce 25199 in combination with gentamicin. the tissue cage model in rabbits was used to study the cke in vivo after antibiotic treatment of the bacteria in vitro. synergy was observed within two to seven h with all isolates in early logarithmic phase, except with s. aureus, which ... | 1991 | 1930964 |
| two-dimensional 1h nmr studies on hpr protein from staphylococcus aureus: complete sequential assignments and secondary structure. | complete sequence-specific assignments of the 1h nmr spectrum of hpr protein from staphylococcus aureus were obtained by two-dimensional nmr methods. important secondary structure elements that can be derived from the observed nuclear overhauser effects are a large antiparallel beta-pleated sheet consisting of four strands, a, b, c, d, a segment sab consisting of an extended region around the active-center histidine (his-15) and an alpha-helix, a half-turn between strands b and c, a segment scd ... | 1991 | 1932039 |
| [invasive mycoses in liver transplantation]. | seventy three adults underwent orthotopic liver transplantations between february 1987 and november 1989 and were followed (54 retrospectively and 19 in a prospective study) with the aim of establishing the incidence of deep mycoses (3 disseminated candidiasis due to c. albicans, 1 invasive aspergillosis due to a. fumigatus and 1 invasive pulmonary aspergillosis due to a. niger and a. fumigatus). 4/5 of these infections occurred in the first month after transplantation. all the patients were ass ... | 1991 | 1932238 |
| internal mammary artery use. sternal revascularization and experimental infection patterns. | we have described previously the acute sternal devascularization produced by mobilization of one or both internal mammary arteries (imas). the present experiments were conducted to examine the time course of sternal revascularization and infection patterns after ima use. twenty-four 8-week-old domestic pigs were obtained from a herd in which active streptococcus faecalis had been detected in recent litters. after control blood flow procedures (microspheres) were completed, each pig underwent a m ... | 1991 | 1934421 |
| differentiation of enterococci from other group d streptococci by means of a specific monoclonal antibody. | we report on the specificity of a monoclonal antibody which reacts with autoclaved extracts of four species of enterococci but does not react to the same extent with similar extracts from two non-enterococcal group d streptococci. the monoclonal antibody also reacts specifically with purified lipoteichoic acid from streptococcus faecalis but not significantly with purified lipoteichoic acid from the non-enterococcal species streptococcus bovis and streptococcus equinus. the specific antigen dete ... | 1991 | 1936940 |
| stimulation of monokine production by lipoteichoic acids. | lipoteichoic acids (ltas) isolated from bacterial species, including staphylococcus aureus, streptococcus pyogenes a, enterococcus faecalis, streptococcus pneumoniae, and listeria monocytogenes, were tested for their ability to stimulate the production of interleukin-1 beta (il-1 beta), il-6, and tumor necrosis factor alpha in cultured human monocytes. ltas from s. aureus and s. pneumoniae failed to induce monokine production when applied in the concentration range of 0.05 to 5.0 micrograms/ml. ... | 1991 | 1937822 |
| localization of translocating escherichia coli, proteus mirabilis, and enterococcus faecalis within cecal and colonic tissues of monoassociated mice. | normal bacteria can translocate (migrate) across an intact intestinal mucosa, but the anatomical site of bacterial translocation has not been defined. gastrointestinal (gi) cross-sections were obtained from mice monoassociated with high cecal concentrations of escherichia coli, proteus mirabilis, or enterococcus faecalis. as previously reported (c. l. wells, r. p. jechorek, and k. j. gillingham, arch. surg. 126:247-252, 1991), these mice had viable translocating bacteria recovered from mesenteri ... | 1991 | 1937830 |
| enumeration by a miniaturized method of escherichia coli, streptococcus bovis and enterococci as indicators of the origin of faecal pollution of waters. | counts of escherichia coli, faecal streptococci and enterococci were made on faecal specimens from human and animal origin and urban raw sewage waters, with microtiter plates containing selective substances. escherichia coli was more numerous than faecal streptococci and enterococci in 80% of the samples regardless of the origin. consequently the use of the ratio e. coli/faecal streptococci to distinguish human from animal origin of faecal pollution is questionable. enterococcus faecalis was pre ... | 1991 | 1938678 |
| molecular and genetic analysis of a region of plasmid pcf10 containing positive control genes and structural genes encoding surface proteins involved in pheromone-inducible conjugation in enterococcus faecalis. | exposure of enterococcus faecalis cells carrying the tetracycline resistance plasmid pcf10 to the heptapeptide pheromone ccf10 results in an increase in conjugal transfer frequency by as much as 10(6)-fold. pheromone-induced donor cells also express at least two plasmid-encoded surface proteins, the 130-kda sec 10 protein, which is involved in surface exclusion, and the 150-kda asc10 protein, which has been associated with the formation of mating aggregates. previous subcloning and transposon mu ... | 1991 | 1938961 |
| role of the pheromone-inducible surface protein asc10 in mating aggregate formation and conjugal transfer of the enterococcus faecalis plasmid pcf10. | the high transfer frequency of pheromone-inducible conjugative plasmids of enterococcus faecalis in liquid culture is due in part to the formation of mating aggregates. these aggregates result from the interaction of two surface components, aggregation substance (as), which is plasmid encoded, and the chromosomally encoded binding substance (bs). in the accompanying paper (s.-m. kao, s. b. olmsted, a. s. viksnins, j.c. gallo, g. m. dunny, j. bacteriol, 173:7650-7664, 1991), the sequence of the p ... | 1991 | 1938962 |
| structure of nadh peroxidase from streptococcus faecalis 10c1 refined at 2.16 a resolution. | the crystal structure of nadh peroxidase (ec 1.11.1.1) from streptococcus faecalis 10c1 (enterococcus faecalis) has been refined to a resolution of 2.16 a using the simulated annealing method. the final crystallographic r-factor is 17.7% for all data in the resolution range 7 to 2.16 a. the standard deviations are 0.015 a in bond lengths and 3.0 degrees in bond angles for the final model, which includes all 447 amino acid residues, one fad and 369 water molecules. the enzyme is a symmetrical tet ... | 1991 | 1942054 |
| bacterial growth on suction drain tips. prospective study of 489 clean orthopedic operations. | the study included 489 clean orthopedic operations with implantation of major foreign materials (joint replacements and internal fixations of fractures). specimens for culture were taken from the suction drainage system, either from the drain fluid or from the drain-tube tip or from both. six superficial and five deep infections were seen following the operations. only two cultures of drain fluid were positive, and neither of these became infected. positive drain-tip cultures were seen after 56 ... | 1991 | 1950489 |
| nucleotide sequence of the beta-lactamase gene from enterococcus faecalis hh22 and its similarity to staphylococcal beta-lactamase genes. | the nucleotide sequence of the constitutively produced beta-lactamase (bla) gene from enterococcus faecalis hh22 was shown to be identical to the published sequences of three of four staphylococcal type a beta-lactamase genes; more differences were seen with the genes for staphylococcal type c and d enzymes. one hundred forty nucleotides upstream of the beta-lactamase start codon were determined for an inducible staphylococcal beta-lactamase and were identical to those of the constitutively expr ... | 1991 | 1952840 |
| mechanism of action of bay v 3522, a new cephalosporin with unusually good activity against enterococci. | the in vitro activity of bay v 3522, a new cephalosporin with unusually good activity against enterococci, was tested on 100 clinical isolates of enterococcus faecalis. the mic for 86.3% of the strains was 4 micrograms/ml, whereas the mic for 13.7% ranged from 8 to 16 micrograms/ml. no differences were found between mics determined with low- or high-density inocula. the bactericidal activity of bay v 3522 was tested on eight clinical strains; most strains showed a ca. 3-log decrease of the origi ... | 1991 | 1952864 |
| lack of homology of enterococci which have high-level resistance to trimethoprim with the dfra gene of staphylococcus aureus. | multiresistant enterococci were tested for susceptibility to trimethoprim (tmp). although most enterococci are inhibited by less than or equal to 1.0 microgram/ml, the mics for 7 of 29 selected multiresistant isolates were greater than or equal to 8 micrograms/ml, including for two beta-lactamase positive (bla+) strains, for which the mics of tmp were greater than 1,000 micrograms/ml, and for another bla+ strain, for which the mic was 128 micrograms/ml. none of five isolates tested transferred t ... | 1991 | 1952870 |
| species identification and antibiotic susceptibility testing of enterococci isolated from hospitalized patients. | a total of 236 enterococci from hospitalized patients were identified to the species level, and their susceptibilities to 11 antibiotics were determined. overall, 195 (82.6%) and 38 (16.1%) isolates were identified as enterococcus faecalis and e. faecium, respectively, but the species distribution as determined from blood culture isolates differed markedly. a total of 27 (63.2%) e. faecium isolates, but no e. faecalis strains, were ampicillin resistant (mic, greater than 8 micrograms/ml). high-l ... | 1991 | 1952875 |
| detection and prevalence of listeria monocytogenes in the agricultural ecosystem. | the sensitivity of four different enrichment procedures to detect listeria monocytogenes in the presence of high levels of streptococcus faecalis was investigated. defined mixed cultures of strep. faecalis and l. monocytogenes gave better results with one-stage enrichment techniques. for manure samples, however, two-stage enrichment techniques gave the best performance. the so-called cold enrichment techniques were found to be unsatisfactory for samples from natural environments. the following m ... | 1991 | 1955415 |
| high-level gentamicin resistance in enterococcus faecalis bacteremia. | in a retrospective analysis, patients with bacteremia due to enterococcus faecalis with and without high-level gentamicin resistance (gre; mic greater than 2000 micrograms/ml) were compared. bacteremic patients with gre (n = 32) had significantly higher rates of nosocomial acquisition and bladder catheterization, longer hospitalizations, and more frequent prior treatment with cephalosporins than did bacteremic patients without high-level resistance (n = 19). overall mortality was significantly a ... | 1991 | 1955722 |
| phosphate-dependent sodium transport in s. faecalis investigated by 23na and 31p nmr. | na+ movements in s. faecalis were studied by 23na nmr. they proved to be dependent on phosphate concentration in the buffer during the de-energization step. k+ and h+ were also studied respectively by potentiometry and 31p nmr and were shown not to be implicated. for de-energized cells the internal phosphate concentration, on the contrary, was directly linked to the external phosphate contained in the buffer. the experiments showed a na+/pi dependence in this prokaryote so far known only in euka ... | 1991 | 1958221 |
| [antibiotic sensitivity of bacteria isolated from patients at 6 hospitals in osaka]. | we examined mics of 6 oral new quinolones and 4 oral cephems against bacteria isolated from patients at 6 hospitals in osaka during the period from january to june in 1990, and the following results were obtained. 1. all species excluding streptococcus pyogenes were more sensitive with less frequencies of resistance to new quinolones than to cephems. in new quinolones, tosufloxacin (tflx) was the most active against gram-positive cocci and ciprofloxacin (cpfx) and tflx had the highest activities ... | 1991 | 1960855 |
| [antibacterial activities of ofloxacin against recent isolates from patients with community-acquired infections]. | in order to survey antibacterial activities of ofloxacin (oflx) against 1,440 bacterial strains isolated from patients with community-acquired infections in 1987 and 1990, minimum inhibitory concentrations (mics) of the drug as well as those of other new quinolones and oral cephems were determined. the following conclusions were reached. 1. comparison of the mic distribution for strains isolated in 1987 with those in 1990 suggested a tendency toward an increase in the frequency of oflx-resistant ... | 1991 | 1960856 |
| transferable plasmid-mediated antibiotic resistance in listeria monocytogenes. | a strain of listeria monocytogenes, isolated from a patient with meningoencephalitis, was resistant to chloramphenicol, erythromycin, streptomycin, and tetracycline. the genes conferring resistance to these antibiotics were carried by a 37-kb plasmid, pip811, that was self-transferable to other l monocytogenes cells, to enterococci-streptococci, and to staphylococcus aureus. the efficacy of transfer and the stability of pip811 were higher in enterococci-streptococci than in the other gram-positi ... | 1990 | 1972210 |
| the distribution of aztreonam in serum, bile, skin and subcutaneous tissues in patients undergoing cholecystectomy. | the distribution of aztreonam was measured in patients undergoing elective cholecystectomy. in 14 patients 2 g aztreonam was injected preoperatively and the concentration of the antibiotic was assessed in the bile from the gall bladder and common bile duct, subcutaneous tissues and serum. samples from bile and any wound discharge were cultured and sensitivities determined. the antibiotic reached bactericidal levels in the common bile duct within 30 min of injection and such levels were maintaine ... | 1990 | 1972956 |
| mobilization of the gentamicin resistance gene in enterococcus faecalis. | enterococcus faecalis plasmid pbem10 (a conjugative plasmid encoding beta-lactamase production and gentamicin resistance [gmr]) was made transfer deficient by using tn917. relocation of the gmr determinant into two sites on pcf10 was observed. restriction analysis revealed insertion of a common 2.5-kilobase-pair hindiii and a 3.9-kilobase-pair haeiii fragment encoding gmr, suggesting that this determinant resides on a transposon similar to tn4001. | 1990 | 1975489 |
| antimicrobial actions of calcium binding leucocyte l1 protein, calprotectin. | the calcium binding l1 protein was found to inhibit growth of blood culture isolates of candida spp and cerebrospinal fluid isolates of cryptococcus neoformans. minimum inhibitory concentrations (mic) were 4-128 mg/l, and concentrations 2-4 times the mic were fungicidal. blood culture isolates of escherichia coli, klebsiella spp, staphylococcus aureus, and staphylococcus epidermidis had mic values of 64-256 mg/l. antibacterial activity was strongly influenced by the nature of the culture medium. ... | 1990 | 1976144 |
| comparison of genomic dnas of different enterococcal isolates using restriction endonucleases with infrequent recognition sites. | epidemiologic evaluation of enterococci has been limited by the lack of a simple and effective method for comparing strains. in this study, we have compared chromosomal restriction endonuclease digestion patterns of 27 isolates of enterococcus faecalis from three different locations by using pulsed-field electrophoresis of large chromosomal fragments (14 to 1,000 kilobases). all but two isolates generated a clear, evaluable pattern with a single lysis and digestion, and the remaining two were vi ... | 1990 | 1977766 |
| a bacteriological assessment of ampicillin with sulbactam as antibiotic prophylaxis in patients undergoing biliary tract operations. the west of scotland surgical infection study group. | a prospective audit of 644 patients undergoing biliary tract operations has been conducted in ten district general hospitals. all patients received a single dose of ampicillin 2 g and sulbactam 1 g as antibiotic prophylaxis. bacteria were cultured from the bile of 121 patients. in patients with sterile bile the incidence of postoperative infection was 2.5%, while in those with colonized bile it was 22% (p less than 0.0001). the 35 patients from whose bile bacteria of two or more species were iso ... | 1990 | 1979575 |
| antimutagenicity and binding of lactic acid bacteria from a chinese cheese to mutagenic pyrolyzates. | the microbiological characteristics of nai ge da, a traditional cheese in china, was investigated. the lactic acid bacteria species were identified as streptococcus cremoris, streptococcus lactis ssp. diacetylactis, streptococcus faecalis, and leuconostoc paramesenteroides, leuconostoc dextranicum, and leuconostoc mesenteroides. streptococcus cremoris, and leuconostoc paramesenteroides were the dominant strains. the antimutagenicities and binding of strains of s. cremoris and s. lactic ssp. diac ... | 1990 | 1980923 |
| [microflora of drinking water reclaimed from waste water in an hermetically closed environment]. | microorganisms dwelling in drinking water reclaimed from water containing water in an enclosed environment were identified. the microbial species in the water reclaimed from the condensate of hydrogen peroxide decomposition products and from the air humidity condensate showed specific features and differences when compared to those in natural water. | 1990 | 1981380 |
| endophthalmitis from contaminated donor corneas following penetrating keratoplasty. | we encountered six (0.2%) cases of endophthalmitis resulting from contaminated donor corneas between january 1983 and july 1990 following a total of 3000 consecutive penetrating keratoplasties. causative organisms in the three cases of fungal endophthalmitis were torulopsis glabrata, candida albicans, and aspergillus flavus; the three cases of bacterial endophthalmitis were due to klebsiella pneumoniae, staphylococcus aureus, and enterococcus faecalis. all organisms were resistant to gentamicin ... | 1991 | 1987949 |
| upper genital tract isolates at delivery as predictors of post-cesarean infections among women receiving antibiotic prophylaxis. | the introduction of antibiotic prophylaxis for cesarean delivery has decreased the risk of postpartum endometritis and wound infection, but factors that contribute to prophylaxis failure are not understood. to determine factors that might contribute to postpartum infections following antibiotic prophylaxis, we cultured amniotic fluid, decidua, and chorioamniotic membrane specimens for anaerobic and facultative bacteria and for genital mycoplasmas at cesarean delivery. women were assessed daily f ... | 1991 | 1988895 |
| prostatitis. | several distinct types of prostatitis, or prostatitis syndromes, are now recognized. the most common forms include acute and chronic bacterial prostatitis, nonbacterial prostatitis, and prostatodynia. bacterial prostatitis, caused mainly by coliform bacteria, pseudomonas, and enterococcus faecalis, is often difficult to cure and usually requires extended therapy (4-16 weeks) with an appropriate antimicrobial agent that achieves therapeutic levels in the prostatic secretory system. about 90% of m ... | 1991 | 1996042 |
| measurement of urinary lipopolysaccharide antibodies by elisa as a screen for urinary tract infection. | five hundred and twenty two clinical urine specimens submitted for routine microbiological examination were tested in parallel by conventional microscopy and culture and for lipopolysaccharide antibodies by an enzyme linked immunoabsorbent assay (elisa) to assess the elisa as a screen for urinary tract infection. when the elisa alone was compared with routine methods the specificity sensitivity, and predictive value of positive and negative tests was 73.2%, 75.7%, 51.1% and 38.5%. for elisa with ... | 1991 | 1997536 |
| the effect of antimicrobial therapy on mixed infections with bacteroides species. is eradication of the anaerobes important? | antimicrobial agents were used alone or in combinations in order to explore their effect on mixed aerobic-anaerobic infections. subcutaneous abscesses were induced in mice by single and mixed infections of bacteroides fragilis, bacteroides melaninogenicus, staphylococcus aureus, streptococcus pyogenes, streptococcus faecalis, escherichia coli, klebsiella pneumoniae and pseudomonas aeruginosa. the infected animals were treated for 5 days with spiramycin, gentamicin or metronidazole alone, or metr ... | 1991 | 2002230 |
| effect of hydrogen peroxide on growth of candida, cryptococcus, and other yeasts in simulated blood culture bottles. | the addition of hydrogen peroxide to blood contained in liquid culture medium increased the dissolved-o2 partial pressure in direct proportion to the volume injected. the effect of hydrogen peroxide on the growth of subcultured clinical isolates of candida albicans, cryptococcus neoformans, torulopsis glabrata, and other yeasts and on the growth of blood culture isolates of representative pathogenic bacteria was compared with its effect on their growth in vented and unvented stationary bottles. ... | 1991 | 2007641 |
| isolation of vancomycin-resistant enterococci in haematologic patients. | after the occurrence of septicaemia with a vancomycin-resistant enterococcus faecalis strain in a patient, it was decided to determine the number of carriers of vancomycin-resistant cocci among haematologic patients. during a period of six months 135 stool samples from 25 children, and 400 samples from 70 adults were studied. all samples from the children were negative for vancomycin-resistant cocci. nine of the adult patients had cultures positive for cocci, all identified as enterococci, which ... | 1991 | 2009875 |
| in vitro antibacterial activities of pd 131628, a new 1,8-naphthyridine anti-infective agent. | pd 131628 is a new aminopyrrolidine-substituted fluorocyclopropyl naphthyridine quinolone which possesses high in vitro activity against a wide spectrum of bacterial species. the mics for greater than or equal to 90% of strains were 0.125 to 0.25 microgram/ml for staphylococci, streptococcus pyogenes, and s. pneumoniae; 0.5 micrograms/ml for s. agalactiae and enterococcus faecalis; 0.125 micrograms/ml for members of the family enterobacteriaceae and acinetobacter spp.; 0.5 micrograms/ml for pseu ... | 1991 | 2014970 |
| antibiosis of leuconostoc gelidum isolated from meat. | a heterofermentative lactic acid bacterium isolated from meat packaged under elevated co2 levels was identified as leuconostoc gelidum, based on the description of this new species by shaw & harding (1989). it grows well at refrigeration temperatures but not at 35 degrees c. the organism produces an inhibitory substance that is inactivated by protease and trypsin, but not by catalase or by heating at 62 degrees c, for 30 min. the bacteriocin-like inhibitory substance is produced early in the gro ... | 1991 | 2019548 |
| comparison of silver sulfadiazine 1% with chlorhexidine digluconate 0.2% to silver sulfadiazine 1% alone in the prophylactic topical antibacterial treatment of burns. | wound bacterial colonization in 118 patients treated with chlorhexidine digluconate 0.2% in silver sulfadiazine 1% applied daily to the burn wounds was compared to that of 135 comparable patients similarly treated with silver sulfadiazine 1%. with chlorhexidine digluconate 0.2% in silver sulfadiazine 1%, colonization by staphylococcus aureus was less frequent (38%) than with silver sulfadiazine (54%, p = 0.016). no statistical difference was found for colonization by enterococcus faecalis, pseud ... | 1991 | 2022674 |
| antimicrobial screening of medicinal plants from baja california sur, mexico. | the ethanolic extracts of 72 plants belonging to 35 different families, and used in traditional medicine in baja california sur (méxico), were tested for antimicrobial activity in vitro using the filter paper disk assay method. activity against staphylococcus aureus, bacillus subtilis, streptococcus faecalis (gram-positive microorganisms), escherichia coli (gram-negative microorganisms) and candida albicans (yeast) is discussed. | 1991 | 2023427 |
| [etiological structure and resistance to antibacterial drugs of causative agents of cross infection in donetsk]. | tests for hemocultures were performed in 51 patients with clinical diagnoses of sepsis treated in a reanimation unit. microbial cultures were isolated from 30 patients (58.9 per cent). staphylococci in pure cultures and associations were the causative agents of sepsis in 26 patients (86.4 per cent). the cultures of e. coli, y. enterocolitica and streptococcus faecalis were isolated from 2, 1 and 1 patients, respectively. pus specimens from 111 patients with postinjection suppuration were tested ... | 1991 | 2025110 |
| susceptibility of female pelvic pathogens to oral antibiotic agents in patients who develop postpartum endometritis. | fifteen hundred patients were enrolled in a prospective, randomized study on the effect of antibiotic prophylaxis during cesarean section. two hundred thirty-one patients developed postpartum endometritis, and the isolates obtained from the endometrium were tested for sensitivity to ampicillin, cefuroxime, ofloxacin, ciprofloxacin, and clindamycin. minimum inhibitory concentrations of 50% and 90% of ampicillin, cefuroxime, and clindamycin were similar to previously reported values; however, slig ... | 1991 | 2031518 |
| comparison of silver sulphadiazine 1 per cent, silver sulphadiazine 1 per cent plus chlorhexidine digluconate 0.2 per cent and mafenide acetate 8.5 per cent for topical antibacterial effect in infected full skin thickness rat burn wounds. | silver sulphadiazine 1 per cent (ss), silver sulphadiazine 1 per cent plus chlorhexidine digluconate 0.2 per cent (ss + cd 0.2 per cent) and mafenide acetate 8.5 per cent (ma) were compared to assess the antibacterial effect of once daily application on experimental rat 20 per cent full skin thickness burn wounds seeded 24 h earlier with 10(8) microorganisms originally isolated from infected wounds of burned patients. separate series evaluated staph. aureus, enterococcus faecalis, enterobacter c ... | 1991 | 2031672 |
| in vitro and in vivo antibacterial activities of e-4497, a new 3-amine-3-methyl-azetidinyl tricyclic fluoroquinolone. | the in vitro and in vivo antibacterial activities of a new tricyclic fluoroquinolone, e-4497 [s(-)-9-fluoro-3-methyl-10-(3-amine-3-methyl-azetidin-1-yl)-7-oxo- 2,3-dihydro- 7h-pyrido-(1,2,3-de)-1,4-benzoxazine-6-carboxylic acid], were evaluated in comparison with those of dr-3355 [s-(-)-ofloxacin], norfloxacin, and ciprofloxacin. e-4497 was more potent than norfloxacin and as potent as or more potent than dr-3355 and ciprofloxacin against staphylococcus spp., streptococcus spp., and enterococcus ... | 1991 | 2039195 |
| viable but nonculturable bacteria in drinking water. | klebsiella pneumoniae, enterobacter aerogenes, agrobacterium tumefaciens, streptococcus faecalis, micrococcus flavus, bacillus subtilis, and pseudomonas strains l2 and 719 were tested for the ability to grow and maintain viability in drinking water. microcosms were employed in the study to monitor growth and survival by plate counts, acridine orange direct counts (aodc), and direct viable counts (dvc). plate counts dropped below the detection limit within 7 days for all strains except those of b ... | 1991 | 2039237 |
| [the influence of cefpirome on intestinal bacterial flora]. | cefpirome (cpr, hr810), a new parenteral cephalosporin antibiotic, was studied for its effect on the intestinal bacterial flora in pediatric patients. the subjects were children admitted for infections (6 males and 3 females, 1 month to 5 years 1 month old, weighted 3.94 to 21.0 kg). cpr was intravenously administered at a dose between 19.0 to 40.0 mg/kg, 3 to 4 doses daily over 6 to 12 days. the feces from these children were collected before, during, and after administration, and bacteria were ... | 1991 | 2041149 |
| [antibacterial activity of ciprofloxacin against fresh clinical isolates from superficial suppurative foci]. | the minimum inhibitory concentrations (mics) of 5 drugs (ciprofloxacin (cpfx), and 4 drugs used as standard) were determined to investigate antibacterial potencies of cpfx against bacterial strains isolated in 1989 from superficial suppurative foci. the clinical isolates tested included 375 strains from 11 aerobic bacterial species, and 50 strains from 2 anerobic bacterial genera (group) for a total of 425 isolates. interpreting mic level distributions of these drugs as the expression of antibac ... | 1991 | 2041153 |
| effects of high hydrostatic pressure on characteristics of pork slurries and inactivation of microorganisms associated with meat and meat products. | pork slurries inoculated with various test microorganisms were prepared and subjected to high hydrostatic pressure at 1000 to 6000 atm for 10 min at 25 degrees c to examine for the pressure effects on characteristics of the slurries and the inactivation of the microorganisms associated with meat and meat products. pressure treatment at higher than 3000 atm caused coagulation and discoloration of the pork slurries. harder and more white coagulants were obtained by increasing the pressure. pressur ... | 1991 | 2049285 |
| penetration into tissues of various drugs active against gram-positive bacteria. | gram-positive bacteria are the most important pathogens causing hospital- and community-acquired infections. we therefore reviewed the penetration of various antibiotics active against gram-positive bacteria including methicillin-resistant staphylococcus aureus into tissues, where staphylococcal infections are common. rifampicin reaches heart valve concentrations of 65% of the simultaneous serum levels. at 8 h after administration blood and tissues concentrations of rifampicin exceeded the mic90 ... | 1991 | 2055819 |
| aztreonam versus gentamicin for short-term prophylaxis in biliary and gastric surgery. | short-term antibiotic prophylaxis was studied in 80 patients undergoing biliary or gastric surgery. the patients were randomized to receive 1 g of aztreonam or 80 mg of gentamicin intravenously 30 minutes before surgery and 8 and 16 hours after surgery. of samples taken from the abdominal cavity for bacteriologic study, 53% were culture positive. wound infections developed in two (4.5%) of 44 patients receiving aztreonam and in seven (19.4%) of 36 patients treated with gentamicin. staphylococcus ... | 1991 | 2068469 |
| [a case of mediastinal abscess due to enterococcus faecalis accompanied with superior vena cava syndrome]. | superior vena cava (svc) syndrome caused by benign diseases is rare. we reported a case of mediastinal abscess due to enterococcus faecalis (e. faecalis) accompanied with svc syndrome and reviewed the literature on this particular condition. a 38-year-old female with swelling of the neck and dilatation of cervical vein was admitted to our hospital, being diagnosed as having a svc syndrome. chest roentgenogram revealed an enlargement of the right upper mediastinum and a massive infiltration in th ... | 1991 | 2071954 |
| [survey on clinical isolates from 13 hospitals in akita prefecture--changes in frequency and susceptibility of isolates by scale of hospital. survey group for clinical isolates, chemotherapy research committee of akita prefecture]. | isolates from various clinical materials in 13 hospitals in akita prefecture and their drug susceptibility were investigated by the chemotherapy research committee of akita prefecture during the period from dec., 1987 to feb., 1988. the results were as follows: 1. the total number of isolates was 8,387, including staphylococcus aureus (18.9%), pseudomonas aeruginosa (10.9%), staphylococcus epidermidis (7.3%) and enterococcus faecalis (6.6%). s, aureus and p. aeruginosa were detected more frequen ... | 1990 | 2074368 |
| in-vitro activity of sparfloxacin, a new quinolone antimicrobial agent. | the in-vitro activity of sparfloxacin (at-4140), a new difluorinated quinolone, was compared with those of ciprofloxacin, temafloxacin and selected members of other groups of antimicrobial agents, against 651 recent distinct clinical isolates and strains with known mechanisms of resistance. three strains of chlamydia trachomatis were also studied. the mics for 90% of the enterobacteriaceae were between 0.06 and 1 mg/l; for pseudomonas aeruginosa the mic90 was 2 mg/l. sparfloxacin was 16-fold mor ... | 1990 | 2079449 |
| [anaerobic bacteria detected in inflammatory conditions of the respiratory tract]. | in this study a participation of anaerobic bacteria in respiratory tract diseases is presented. bronchial washings collected by ++fibrobronchoscope constituted material for the study. immediately after collection the material was plated onto two media for aerobic bacteria (hemomedium) and anaerobic bacteria (anaeromedium). then, the samples were centrifuged and a sediment was plated on solid media suitable for aerobic and anaerobic bacteria. bacterial anaerobic isolates were identified by using ... | 1990 | 2084446 |
| synthesis and antimicrobial activities of some new tetrahydro-2h-1,3,5-thiadiazine-2-thione derivatives of cephalexin. | in this study, compounds with a 7-[2-(dihydro-5-substituted 6-thioxo-2h-1,3,5-thiadiazine-3[4h]-yl)-2-phenyl]acetamido-3 -methyl-3- cephem-4-carboxylic acid structure were synthesized by reacting cephalexin monohydrate with formaldehyde and dithiocarbamic acid salts prepared from some primary amines. the structure of the compounds was confirmed by spectral data and elementary analysis. the antimicrobial activities of the compounds were investigated against some bacteria (staphylococcus aureus, s ... | 1990 | 2085339 |
| clinical evaluation of the imipenem/cilastatin combination in the therapy of severe infections in patients with malignant diseases. | thirty hospitalized patients (23 men and 7 women), aged 42 to 78 years, with impaired host defences for malignant underlying diseases and affected by life-threatening infections, were treated with the imipenem/cilastatin combination at a dosage ranging between 2 and 4 g daily i.v. at 8 or 12 h intervals. the average length of therapy was 9.6 +/- 2.09 days. the isolated organisms were as follows: pseudomonas aeruginosa [12], escherichia coli [10], klebsiella pneumoniae [5], proteus mirabilis [3], ... | 1990 | 2086164 |
| [susceptibilities of clinical bacterial isolates to antimicrobial agents. a study mainly focused on imipenem. research group for testing imipenem susceptibility on clinical isolates]. | we investigated susceptibilities of clinical bacterial isolates to imipenem (ipm) and other antimicrobial agents at 459 hospital laboratories throughout japan from september to december of 1988. in this study, identification and susceptibility testing were performed at each hospital laboratory and the tests were carried out according to the 1-dilution or 3-dilution disc technique in which susceptibilities are classified into 4 grades: , ++, + and -. ipm had significantly high activity against st ... | 1990 | 2086814 |
| comparative in vitro and in vivo activities of six new monofluoroquinolone and difluoroquinolone 3-carboxylic acids with a 7-azetidin ring substituent. | e-4502, e-4501, e-4500, e-4480, e-4474, and e-4441 are new monofluorinated or difluorinated quinolone agents that are chemically characterized by the presence of an azetidin ring, with different c'-3 substituents, at position 7 of the molecular structure. the mics of the difluorinated compounds e-4501, e-4474, and e-4441 for 90% of isolates were 0.06 to 1, 0.06 to 1, and 0.12 to 1 microgram/ml, respectively, against gram-positive organisms (staphylococci, streptococci, and enterococcus faecalis) ... | 1990 | 2088187 |
| investigations of the activity by contact of miconazole sulfosalicylate. | the in-vitro antimicrobial activity of miconazole sulfosalicylate (m.ssa) has been investigated on mycetes (candida albicans, cryptococcus neoformans, aspergillus niger, trichophyton mentagrophytes), gram-positive bacteria (staphylococcus aureus, streptococcus faecalis) and gram-negative bacteria (escherichia coli, pseudomonas aeruginosa, serratia marcescens and proteus vulgaris) in comparison with miconazole nitrate (m.nit). the results showed m.ssa has a greater activity than m.nit, particular ... | 1990 | 2093108 |
| an in vitro study of the diffusibility of intracanal medicaments. | in this study, the diffusion properties of the vapors of four canal antiseptics were examined. tricresol, camphore-chlorophenol, cresophene, and povidone-iodine in clinical doses were tested against staphylococcus aureus and streptococcus faecalis. forty-five extracted human maxillary central incisor teeth were used, and their root canals were prepared. a small amount of antiseptic was placed on a cotton pellet in the pulp chamber of each tooth, and the chamber was sealed with cavit. vapors from ... | 1990 | 2094869 |
| clinical experience with pefloxacin in patients with urinary tract infections. | a total of 27 patients, 21 of them females, with a median age of 56 were treated with pefloxacin for urinary tract infections. some 74% of these infections were associated with upper tract symptoms, and escherichia coli was the most common causative micro-organism (75% of cases). fifteen patients had co-existent diseases with/without urological abnormalities. all strains of e coli were sensitive to pefloxacin; actinobacter and one strain of klebsiella and streptococcus faecalis were resistant. t ... | 1990 | 2102145 |
| [changes in phagocytosis of aerobic bacteria by neutrophils after exposure to subinhibitory concentrations of aztreonam and ciprofloxacin]. | in the present research work we are performing a study on the effect of the antibiotic concentrations low minimal inhibitory concentration of aztreonam and ciprofloxacin on phagocytosis of aerobic bacteria by neutrophils (enterococcus faecalis, staphylococcus aureus, escherichia coli and pseudomonas aeruginosa). both antibiotics induced an increased of phagocytosis by similar mechanisms. in our assay aztreonam and ciprofloxacin would not act directly on granulocyte but they would affect the bact ... | 1990 | 2103236 |