Publications
| Title | Abstract | Year Filter | PMID(sorted ascending) Filter |
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| transmission of beauveria bassiana from male to female aedes aegypti mosquitoes. | resistance to chemical insecticides plus high morbidity rates have lead to rising interest in fungi as candidates for biocontrol agents of mosquito vectors. in most studies fungal infections have been induced by exposure of mosquitoes to various surfaces treated with conidia. in the present study eight mexican strains of beauveria bassiana were assessed against aedes aegypti by direct exposure of females to 6 × 10(8) conidia ml (-1) on a filter paper, afterwards, the transmission of the least an ... | 2011 | 21352560 |
| the wmelpop strain of wolbachia interferes with dopamine levels in aedes aegypti. | wolbachia is an intracellular bacterium that has been stably transinfected into the mosquito vector of dengue, aedes aegypti. this inherited infection causes a range of metabolic and phenotypic alterations in the mosquito, which might be related to neuronal abnormalities. in order to determine if these alterations were caused by the manipulation of neuroamines by this bacterium, we studied the expression of genes involved in the dopamine biosynthetic pathway and also measured the amount of dopam ... | 2011 | 21356077 |
| mapping protein interactions between dengue virus and its human and insect hosts. | dengue fever is an increasingly significant arthropod-borne viral disease, with at least 50 million cases per year worldwide. as with other viral pathogens, dengue virus is dependent on its host to perform the bulk of functions necessary for viral survival and replication. to be successful, dengue must manipulate host cell biological processes towards its own ends, while avoiding elimination by the immune system. protein-protein interactions between the virus and its host are one avenue through ... | 2011 | 21358811 |
| mosquito infestation and dengue virus infection in aedes aegypti females in schools in merida, mexico. | we determined abundance of aedes aegypti mosquitoes and presence of dengue virus (denv) in females collected from schools in mérida, méxico, during 2008 and 2009. backpack aspiration from 24 schools produced 468 females of ae. aegypti and 1,676 females of another human biter, culex quinquefasciatus. ae. aegypti females were collected most commonly from classrooms followed by offices and bathrooms. of these females, 24.7% were freshly fed. examination of 118 pools of ae. aegypti females (total of ... | 2011 | 21363990 |
| genetic elimination of dengue vector mosquitoes. | an approach based on mosquitoes carrying a conditional dominant lethal gene (release of insects carrying a dominant lethal, ridl) is being developed to control the transmission of dengue viruses by vector population suppression. a transgenic strain, designated ox3604c, of the major dengue vector, aedes aegypti, was engineered to have a repressible female-specific flightless phenotype. this strain circumvents the need for radiation-induced sterilization, allows genetic sexing resulting in male-on ... | 2011 | 21383140 |
| evaluation of the dengue ns1 ag strip-« for detection of dengue virus antigen in aedes aegypti (diptera: culicidae). | dengue fever is currently one of the most important mosquito-borne diseases that affect humans. with neither vaccines nor treatment available, prevention of the disease relies heavily on surveillance and control of mosquito vectors. in the present study, we have evaluated and showed the potential use of the dengue ns1 ag strip(-«) for the detection of dengue virus (denv) in aedes aegypti. initial results showed that the sensitivity of the test kit in detecting denv in wild-caught mosquitoes is c ... | 2011 | 21395416 |
| susceptibility of field-collected aedes aegypti (l.) (diptera: culicidae) to bacillus thuringiensis israelensis and temephos. | the susceptibility status of field-collected aedes aegypti (l.) from a dengue endemic area to bacillus thuringiensis israelensis (bti) and temephos was determined. since august 2007, biweekly ovitrap surveillance (os) was conducted for 12 mo in 2 sites, a & b, in shah alam, selangor. site a was treated with a bti formulation, vectobac® wg at 500 g/ha, from december 2007 - june 2008 while site b was subjected to routine dengue vector control activities conducted by the local municipality. aedes a ... | 2010 | 21399591 |
| dengue infection increases the locomotor activity of aedes aegypti females. | aedes aegypti is the main vector of the virus causing dengue fever, a disease that has increased dramatically in importance in recent decades, affecting many tropical and sub-tropical areas of the globe. it is known that viruses and other parasites can potentially alter vector behavior. we investigated whether infection with dengue virus modifies the behavior of aedes aegypti females with respect to their activity level. | 2011 | 21408119 |
| detection of sequences from a potentially novel strain of cell fusing agent virus in mexican stegomyia (aedes) aegypti mosquitoes. | flaviviruses (fvs) are a very heterogeneous group of viruses that includes viruses capable of infecting insects and/or vertebrates. different human-disease-causing fvs are disseminated by mosquitoes, and therefore, the search for fv in these insects has recently been proposed in order to evaluate their potential transmission in a given community. an entomological survey was carried out in colima (the hyperendemic dengue fever transmission zone in mexico) to collect culicidae in urban and wild ar ... | 2011 | 21409444 |
| temperature induces trade-offs between development and starvation resistance in aedes aegypti (l.) larvae. | heightened temperature increases the development rate of mosquitoes. however, in aedes aegypti (diptera: culicidae), the larvae of which commonly experience limited access to food in urban habitats, temperature effects on adult production may also be influenced by changes in the capacity of larvae to survive without food. we carried out experiments to investigate the effects of temperatures increasing at intervals of 2 °c from 20 °c to 30 °c on the growth, maturation rate and longevity of optima ... | 2011 | 21410734 |
| rhythms and synchronization patterns in gene expression in the aedes aegypti mosquito. | aedes aegypti is arguably the most studied of all mosquito species in the laboratory and is the primary vector of both dengue and yellow fever flaviviruses in the field. a large number of transcriptional studies have been made in the species and these usually report transcript quantities observed at a certain age or stage of development. however, circadian oscillation is an important characteristic of gene expression in many animals and plants, modulating both their physiology and behavior. circ ... | 2011 | 21414217 |
| evidence on impact of community-based environmental management on dengue transmission in santiago de cuba. | during the dengue outbreak that struck santiago de cuba in 2006-2007, we conducted an observational study in the mariana grajales district, the former setting of a community trial for aedes aegypti control. in the trial, community working groups (cwg) had been created in 29 randomly selected intervention house blocks, and routine vector control activities alone were conducted in the remaining 30 control blocks. the cwg elaborated and implemented with the population plans and activities to reduce ... | 2011 | 21418448 |
| towards a semen proteome of the dengue vector mosquito: protein identification and potential functions. | no commercially licensed vaccine or treatment is available for dengue fever, a potentially lethal infection that impacts millions of lives annually. new tools that target mosquito control may reduce vector populations and break the cycle of dengue transmission. male mosquito seminal fluid proteins (sfps) are one such target since these proteins, in aggregate, modulate the reproduction and feeding patterns of the dengue vector, aedes aegypti. as an initial step in identifying new targets for deng ... | 2011 | 21423647 |
| blood meal-derived heme decreases ros levels in the midgut of aedes aegypti and allows proliferation of intestinal microbiota. | the presence of bacteria in the midgut of mosquitoes antagonizes infectious agents, such as dengue and plasmodium, acting as a negative factor in the vectorial competence of the mosquito. therefore, knowledge of the molecular mechanisms involved in the control of midgut microbiota could help in the development of new tools to reduce transmission. we hypothesized that toxic reactive oxygen species (ros) generated by epithelial cells control bacterial growth in the midgut of aedes aegypti, the vec ... | 2011 | 21445237 |
| a secure semi-field system for the study of aedes aegypti. | new contained semi-field cages are being developed and used to test novel vector control strategies of dengue and malaria vectors. we herein describe a new quarantine insectary level-2 (qic-2) laboratory and field cages (james cook university mosquito research facility semi-field system; mrf sfs) that are being used to measure the impact of the endosymbiont wolbachia pipientis on populations of aedes aegypti in cairns australia. | 2011 | 21445333 |
| oviposition-altering and ovicidal potentials of five essential oils against female adults of the dengue vector, aedes aegypti l. | the oviposition deterrence and ovicidal potential of five different essential oils, peppermint oil (mentha piperita), basil oil (ocimum basilicum), rosemary oil (rosemarinus officinalis), citronella oil (cymbopogon nardus), and celery seed oil (apium graveolens), were assessed against female adults of the dengue vector, aedes aegypti l. multiple concentration tests were carried out where cups containing 1 ml of different concentrations (100%, 10%, 1%, 0.1%) of the oils and 199 ml of water were u ... | 2011 | 21445613 |
| fitness costs of resistance to bti toxins in the dengue vector aedes aegypti. | sustainable insect vector disease control strategies involve delaying the evolution of resistance to insecticides in natural populations. the evolutionary dynamics of resistance in the field is highly dependent on the fitness cost of resistance alleles. to successfully manage resistance evolution in target species, it is not only important to find evidence of fitness cost in resistant insects, but also to determine at which stage of the insect's life it is expressed. here, we show that resistanc ... | 2011 | 21461926 |
| evaluation of the effectiveness of insecticide treated materials for household level dengue vector control. | to assess the operational effectiveness of long-lasting insecticide treated materials (itms), when used at household level, for the control of aedes aegypti in moderately infested urban and suburban areas. | 2011 | 21468313 |
| [ultrastructural alterations in larvae of aedes aegypti subject to labdane diterpene isolated from copaifera reticulata (leguminosae) and a fraction enriched with tannins of magonia pubescens (sapindaceae)]. | dengue is an important public health problem in many countries and its main vector aedes aegypti, is the mosquito most adapted to urban areas. for the first time, the mechanism of action of labdane diterpenoid extracted from copaifera reticulata and the fraction enriched of catechin tannins extracted from magonia pubescens is demonstrated through ultrastructural alterations of aedes aegypti larvae. | 2016 | 21468474 |
| male mating history and body size influence female fecundity and longevity of the dengue vector aedes aegypti. | male reproductive success is dependent on insemination success and reproductive output. during mating, male mosquitoes transfer not just sperm, but also seminal fluid proteins that may have profound effects on mated female biology and behavior. in this study, we investigated the role of male body size and mating history on semen depletion, female longevity, and reproductive success in aedes aegypti l. small and large males were mated in rapid succession with up to five females. our results indic ... | 0 | 21485355 |
| laboratory evaluation of the response of aedes aegypti and aedes albopictus uninfected and infected with dengue virus to deet. | laboratory studies were conducted to compare the response of aedes aegypti (l.) and aedes albopictus (skuse) adults, uninfected and infected with four serotypes of dengue virus to a repellent containing 5% n, n-diethyl-3-methylbenzamide (deet). the results showed that mosquitoes infected with the four serotypes of dengue responded similarly to uninfected mosquitoes. | 2011 | 21485370 |
| temephos resistance and esterase activity in the mosquito aedes aegypti in havana, cuba increased dramatically between 2006 and 2008. | aedes aegypti (l.) (diptera: culicidae) control programmes in cuba rely on the application of the organophosphate temephos for larval control. hence, the monitoring of resistance to this insecticide is an essential component of such programmes. here, 15 field populations from different municipalities of havana city were assayed for resistance to temephos. high levels of resistance were detected in all strains and resistance ratios were highly correlated with esterase activity (p = 0.00001). popu ... | 2011 | 21501201 |
| impact of daily temperature fluctuations on dengue virus transmission by aedes aegypti. | most studies on the ability of insect populations to transmit pathogens consider only constant temperatures and do not account for realistic daily temperature fluctuations that can impact vector-pathogen interactions. here, we show that diurnal temperature range (dtr) affects two important parameters underlying dengue virus (denv) transmission by aedes aegypti. in two independent experiments using different denv serotypes, mosquitoes were less susceptible to virus infection and died faster under ... | 2011 | 21502510 |
| histochemical and ultrastructural studies of the mosquito aedes aegypti fat body: effects of aging and diet type. | aedes aegypti is the principal vector of dengue world wide and a major vector of urban yellow fever. despite its epidemiological importance, not much is known regarding cellular and structural changes in the fat body in this mosquito. here, we applied light and transmission electron microscopies to investigate structural changes in the fat body of three groups of a. aegypti females: newly emerged, 18-day-old sugar-fed, and 18-day-old blood-fed. the fat body consists of a layer of cells attached ... | 2011 | 21509905 |
| first evidence of chikungunya virus infection in assam, northeast india. | during june-september 2008, an illness characterized by fever, headache and joint pain was reported in assam state, northeast india. it presented characteristic features resembling chikungunya or dengue virus infection based on clinical symptoms. dengue and chikungunya igm antibody was detected in 10.0% (28/280) and 3.6% (10/280) patients respectively. the chikungunya positive patients did not travel to and from any endemic region confirming indigenous transmission. persistent arthralgia and hea ... | 2011 | 21511316 |
| spatial modeling of dengue and socio-environmental indicators in the city of rio de janeiro, brazil. | this study analyzed the spatial distribution of dengue in rio de janeiro, brazil, in 2006, and associations between the incidence per 100,000 inhabitants and socio-environmental variables. the study analyzed reported dengue cases among the city's inhabitants, rainfall, breteau index (for aedes aegypti and aedes albopictus), gini index, and social development index. we conducted mapping and used the global moran index to measure the indicators' spatial autocorrelation, which was positive for all ... | 2011 | 21519709 |
| oviposition site selection by the dengue vector aedes aegypti and its implications for dengue control. | because no dengue vaccine or antiviral therapy is commercially available, controlling the primary mosquito vector, aedes aegypti, is currently the only means to prevent dengue outbreaks. traditional models of ae. aegypti assume that population dynamics are regulated by density-dependent larval competition for food and little affected by oviposition behavior. due to direct impacts on offspring survival and development, however, mosquito choice in oviposition site can have important consequences f ... | 2011 | 21532736 |
| efficacy of advanced odomos repellent cream (n, n-diethyl-benzamide) against mosquito vectors. | background & objectives : repellents are commonly used personal protection measures to avoid mosquito bites. in the present study, advanced odomos cream (12% n, n-diethyl-benzamide) was tested for its efficacy against mosquitoes in comparison to deet (n,n-diethyl-3-methyl benzamide). methods: bioassays were conducted to assess the repellency of advanced odomos and deet creams against anopheles stephensi and aedes aegypti. their efficacy was tested on human volunteers applied with different conce ... | 2011 | 21537097 |
| aedes aegypti and aedes albopictus (diptera: culicidae): coexistence and susceptibility to temephos, in municipalities with occurrence of dengue and differentiated characteristics of urbanization. | the aim of the present study was to verify the coexistence between aedes aegypti and aedes albopictus populations in municipalities of the states of paraná and santa catarina with different urbanization profiles where dengue occurs and evaluate their susceptibility to the organophosphate temephos. | 2013 | 21537795 |
| [targeted treatment of aedes aegypti at localities with high risk for dengue transmission, morelos, mexico]. | to determine the relative importance of aedes aegyti breeding sites for potential targeted dengue control interventions in morelos. | 2013 | 21537805 |
| the cost of routine aedes aegypti control and of insecticide-treated curtain implementation. | insecticide-treated curtains (itcs) are promoted for controlling the dengue vector aedes aegypti. we assessed the cost of the routine aedes control program (racp) and the cost of itc implementation through the racp and health committees in venezuela and through health volunteers in thailand. the yearly cost of the racp per household amounted to us$2.14 and $1.89, respectively. the itc implementation cost over three times more, depending on the channel used. in venezuela the racp was the most eff ... | 0 | 21540384 |
| wolbachia and the biological control of mosquito-borne disease. | mosquito-borne diseases such as malaria, dengue fever and filariasis cause an enormous health burden to people living in tropical and subtropical regions of the world. despite years of intense effort to control them, many of these diseases are increasing in prevalence, geographical distribution and severity, and options to control them are limited. the transinfection of mosquitos with the maternally inherited, endosymbiotic bacteria wolbachia is a promising new biocontrol approach. fruit fly wol ... | 2011 | 21546911 |
| insecticide susceptibility of aedes aegypti and aedes albopictus in central africa. | abstract: background: aedes aegypti (linnaeus, 1762) and aedes albopictus (skuse, 1894) are the main vectors of dengue (denv) and chikungunya (chikv) viruses worldwide. as there is still no vaccine or specific treatment for denv and chikv, vector control remains the cornerstone of prevention and outbreak control. unfortunately, vector control programs are facing operational challenges with mosquitoes becoming resistant to commonly used insecticides in several areas through the world. throughout ... | 2011 | 21575154 |
| wolbachia uses host micrornas to manipulate host gene expression and facilitate colonization of the dengue vector aedes aegypti. | the obligate endosymbiont wolbachia pipientis is found in a wide range of invertebrates where they are best known for manipulating host reproduction. recent studies have shown that wolbachia also can modulate the lifespan of host insects and interfere with the development of human pathogens in mosquito vectors. despite considerable study, very little is known about the molecular interactions between wolbachia and its hosts that might mediate these effects. using microarrays, we show that the mic ... | 2011 | 21576469 |
| ovitrap surveillance of the dengue vectors, aedes (stegomyia) aegypti (l.) and aedes (stegomyia) albopictus skuse in selected areas in bentong, pahang, malaysia. | ovitrap surveillance was conducted in methodically selected areas in bentong, pahang, malaysia from june 2008 till december 2009 in order to identify insular sites with stable aedes aegypti population. eleven sites were surveyed in bentong district, pahang, and one of these locations (n3º33' e101º54') was found to have an ovitrap index of ae. aegypti and aedes albopictus ranging from 8%-47% and 37%-78% respectively, indicating that this site could be a high-risk area for dengue outbreak. ae. aeg ... | 2011 | 21602768 |
| does targeting key-containers effectively reduce aedes aegypti population density? | the elimination of aedes aegypti breeding sites has been broadly adopted worldwide to keep vector population density below a critical threshold. we observed the effectiveness of targeting the most productive containers on adult a. aegypti females density, which was evaluated weekly. | 2011 | 21605290 |
| variation in vector competence for dengue viruses does not depend on mosquito midgut binding affinity. | dengue virus genotypes of southeast asian origin have been associated with higher virulence and transmission compared to other genotypes of serotype 2 (den-2). we tested the hypothesis that genetic differences in dengue viruses may result in differential binding to the midgut of the primary vector, aedes aegypti, resulting in increased transmission or vectorial capacity. | 2011 | 21610852 |
| susceptibility of adult female aedes aegypti (diptera: culicidae) to the entomopathogenic fungus metarhizium anisopliae is modified following blood feeding. | abstract: background: the mosquito aedes aegypti, vector of dengue fever, is a target for control by entomopathogenic fungi. recent studies by our group have shown the susceptibility of adult a. aegypti to fungal infection by metarhizium anisopliae. this fungus is currently being tested under field conditions. however, it is unknown whether blood-fed a. aegypti females are equally susceptible to infection by entomopathogenic fungi as sucrose fed females. insect populations will be composed of fe ... | 2011 | 21615890 |
| mosquito species abundance and diversity in malindi, kenya and their potential implication in pathogen transmission. | mosquitoes (diptera: culicidae) are important vectors of human disease-causing pathogens. mosquitoes are found both in rural and urban areas. deteriorating infrastructure, poor access to health, water and sanitation services, increasing population density, and widespread poverty contribute to conditions that modify the environment, which directly influences the risk of disease within the urban and peri-urban ecosystem. the objective of this study was to evaluate the mosquito vector abundance and ... | 2011 | 21626425 |
| prospective field study of transovarial dengue-virus transmission by two different forms of aedes aegypti in an urban area of bangkok, thailand. | a prospective field study was conducted to determine transovarial dengue-virus transmission in two forms of aedes aegypti mosquitoes in an urban district of bangkok, thailand. immature aedes mosquitoes were collected monthly for one year and reared continuously until adulthood in the laboratory. mosquitoes assayed for dengue virus were processed in pools and their dengue virus infection status was determined by one-step rt-pcr and nested-pcr methods. of a total 15,457 newly emerged adult ae. aeg ... | 2011 | 21635652 |
| frequency of pyrethroid resistance in aedes aegypti and aedes albopictus (diptera: culicidae) in thailand. | thirty-two aedes aegypti populations collected throughout thailand and five populations of aedes albopictus from southern thailand were subjected to standard who contact bioassays to assess susceptibility to three commonly used synthetic pyrethroids: permethrin, deltamethrin, and lambda-cyhalothrin. a wide degree of physiological response to permethrin was detected in ae. aegypti, ranging from 56.5% survival (lampang, northern thailand) to only 4% (kalasin in northeastern and phuket in southern ... | 2011 | 21635659 |
| evidence of two lineages of the dengue vector aedes aegypti in the brazilian amazon, based on mitochondrial dna nd4 gene sequences. | genetic variation was estimated in ten samples populations of aedes aegypti from the brazilian amazon, by using a 380 bp fragment of the mitochocondrial nadh dehydrogenase subunit 4 (nd4) gene. a total of 123 individuals were analyzed, whereby 13 haplotypes were found. mean genetic diversity was slightly high (h = 0.666 ± 0.029; π = 0.0115 ± 0.0010). two amova analyses indicated that most of the variation (~70%-72%) occurred within populations. the variation found among and between populations w ... | 2009 | 21637700 |
| complete sequences of mitochondria genomes of aedes aegypti and culex quinquefasciatus and comparative analysis of mitochondrial dna fragments inserted in the nuclear genomes. | we present complete sequences of the mitochondrial genomes for two important mosquitoes, aedes aegypti and culex quinquefasciatus, that are major vectors of dengue virus and lymphatic filariasis, respectively. the a. aegypti mitochondrial genome is 16,655 bp in length and that of c.quinquefasciatus is 15,587 bp, yet both contain 13 protein coding genes, 22 transfer rna (trna) genes, one 12s ribosomal rna (rrna) gene, one 16s rrna gene and a control region (cr) in the same order. the difference i ... | 2011 | 21640823 |
| [increase of entomological indices during the pre-epidemic period of dengue in ben tre, south vietnam.] | dengue has emerged in vietnam 50 years ago and since has become endemo-epidemic throughout the whole country. each year, major epidemics of dengue fever (df) and dengue hemorrhagic fever (dhf) hit south vietnam during the rainy season, causing significant morbidity and mortality, especially among young children. the only preventive measure is vector control, but it is often implemented too late or indiscriminately. the aim of this study was to investigate, in the pre-epidemic stage, the existenc ... | 2011 | 21643648 |
| multiple insecticide resistance in aedes aegypti (diptera: culicidae) populations compromises the effectiveness of dengue vector control in french guiana. | in french guiana, pyrethroids and organophosphates have been used for many years against aedes aegypti. we aimed to establish both the resistance level of ae. aegypti and the ultra low volume spray efficacy to provide mosquito control services with practical information to implement vector control and resistance management. resistance to deltamethrin and fenitrothion was observed. in addition, the profound loss of efficacy of aquak'othrine® and the moderate loss of efficacy of paluthion® 500 wer ... | 2011 | 21655824 |
| risk of dengue occurrence based on the capture of gravid aedes aegypti females using mosquitrap. | we assessed the risk classification of dengue fever based on the capture of aedes aegypti adults using mosquitrap, a type of sticky trap, in comparison with traditional larval infestation indices. a total of 27 mosquitraps were installed, with one trap per block, and were inspected weekly between november 2008-february 2009. infestation baseline data were obtained from a survey conducted prior to trap installation. the index generated by mosquitrap and house index (hi) classified the area "in al ... | 2011 | 21655827 |
| [perinatal dengue infection]. | dengue is a mosquito-borne viral disease, with worldwide distribution in tropical and subtropical areas. argentina was certified free of aedes aegypti in the sixties, however the vector reappered in 1984. in the nineties, small dengue outbreaks occurred with autocthonus diseases at first limited to the northern provinces. in the summer of 2008-2009, autocthonus cases were reported in other parts of the country. vertical dengue virus transmission has been infrequently described, and the effect on ... | 2011 | 21660390 |
| a new strategy for aedes aegypti (diptera: culicidae) control with community participation using a new fumigant formulation. | dengue and dengue hemorrhagic fever are mosquito-borne viral diseases that coincide with the distribution of aedes aegypti (l.), the primary vector in the tropical and semitropical world. with no available vaccine, controlling the dengue vector is essential to avoid epidemics. this study evaluates the efficacy of a new smoke-generating formulation containing pyriproxyfen and permethrin in puerto libertad, misiones, argentina. a fumigant tablet (ft) was applied inside the houses by the community ... | 2011 | 21661319 |
| first dengue virus detection in aedes albopictus from delhi, india: its breeding ecology and role in dengue transmission. | objectiveôçé to report dengue virus and its disease transmission in aedes albopictus in the national capital territory of delhi, india. methodsôçé monthly aedes surveys were carried out in 126 urban localities of delhi in 2008 and 2009. pools of all three species of aedes mosquitoes were tested for dengue virus (denv) using an antigen-capture enzyme-linked immunosorbent assay. resultsôçé aedes aegypti was the most prevalent species, breeding throughout the year. aedes albopictus was found in 9.5 ... | 2011 | 21668590 |
| lower survival rate, longevity and fecundity of aedes aegypti (diptera: culicidae) females orally challenged with dengue virus serotype 2. | as the pathogenic effects of a parasite on its hosts can strongly influence its epidemiology, we compared the life-histories of dengue virus serotype 2 (denv-2)-infected and uninfected aedes aegypti females. unexposed mosquitoes lived longer than exposed ones, but those infected lived longer than exposed but negative (as assayed by real-time quantitative reverse transcription pcr [qrt-pcr]) mosquitoes. infected mosquitoes from a long-established laboratory colony presented more viral rna copies ... | 2011 | 21700303 |
| is routine dengue vector surveillance in central brazil able to accurately monitor the aedes aegypti population? results from a pupal productivity survey. | to assess how well the aedes aegypti infestation rapid survey, levantamento rapido de indice para aedes aegypti (liraa), is able to accurately estimate dengue vector densities and target the most important breeding sites in goiania, brazil. | 2011 | 21702871 |
| pyrethroid resistance reduces the efficacy of space sprays for dengue control on the island of martinique (caribbean). | dengue fever is reemerging on the island of martinique and is a serious threat for the human population. during dengue epidemics, adult aedes aegypti control with pyrethroid space sprays is implemented in order to rapidly reduce transmission. unfortunately, vector control programs are facing operational challenges with the emergence of pyrethroid resistant ae. aegypti populations. | 2011 | 21713017 |
| droplet size and efficacy of an adulticide-larvicide ultralow-volume formulation on aedes aegypti using different solvents and spray application methods. | when cases of dengue are reported or the density of adult aedes aegypti (l.) becomes too high, ultralow-volume (ulv) application of insecticides is the recommended control method. the droplet size of an aerosol insecticide influences its efficiency in killing adult mosquitoes. many studies have been carried out to determine the optimum droplet size that maximises vector control efforts, but only a few have determined droplet-size spectra for specific equipment using different solvents and compar ... | 2012 | 21714060 |
| effect of myracrodruon urundeuva leaf lectin on survival and digestive enzymes of aedes aegypti larvae. | aedes aegypti transmits the viruses that cause yellow and dengue fevers. vector control is essential, since a vaccine for dengue has not as yet been made available. this work reports on the larvicidal activity of myracrodruon urundeuva leaf lectin (mull) against a. aegypti fourth-stage larvae (l(4)). also, the resistance of mull to digestion by l(4) gut proteases and the effects of mull on protease, trypsin-like and α-amylase activities from l(4) gut were evaluated to determine if lectin remains ... | 2012 | 21735148 |
| semaphorin-1a is required for aedes aegypti embryonic nerve cord development. | although mosquito genome projects have uncovered orthologues of many known developmental regulatory genes, extremely little is known about mosquito development. in this study, the role of semaphorin-1a (sema1a) was investigated during vector mosquito embryonic ventral nerve cord development. expression of sema1a and the plexin a (plexa) receptor are detected in the embryonic ventral nerve cords of aedes aegypti (dengue vector) and anopheles gambiae (malaria vector), suggesting that sema1a signal ... | 2011 | 21738767 |
| [behavior of immatures aedes aegypti in the coast state of são paulo, brazil]. | in a region of high dengue incidence, on the coast of the state of são paulo, 9 areas were selected to evaluate the behavior of immature aedes aegypti. | 2011 | 21739074 |
| evaluation of larvicidal activity of acalypha alnifolia klein ex willd. (euphorbiaceae) leaf extract against the malarial vector, anopheles stephensi, dengue vector, aedes aegypti and bancroftian filariasis vector, culex quinquefasciatus (diptera: culicidae). | the leaf extract of acalypha alnifolia with different solvents - hexane, chloroform, ethyl acetate, acetone and methanol - were tested for larvicidal activity against three important mosquitoes such as malarial vector, anopheles stephensi, dengue vector, aedes aegypti and bancroftian filariasis vector, culex quinquefasciatus. the medicinal plants were collected from the area around kallar hills near the western ghats, coimbatore, india. a. alnifolia plant was washed with tap water and shade drie ... | 2012 | 21748350 |
| mosquito larvicidal and ovicidal properties of eclipta alba (l.) hassk (asteraceae) against chikungunya vector, aedes aegypti (linn.) (diptera: culicidae). | the present study deals with the investigation of larvicidal and ovicidal activities of benzene, hexane, ethyl acetate, methanol and chloroform leaf extract of eclipta alba (e. alba) against dengue vector, aedes aegypti (ae. aegypti). | 2011 | 21771410 |
| first report on susceptibility of wild aedes aegypti (diptera: culicidae) using carapa guianensis (meliaceae) and copaifera sp. (leguminosae). | oils of carapa guianensis and copaifera spp. are well known in the amazonian region as natural insect repellent, and studies have reported their efficiency as larvicide against some laboratory mosquito species. however, in wild populations of mosquitoes, these oils have not yet been evaluated. thus, the objective of this study was to investigate their efficiency as larvicide in wild populations of aedes aegypti with a history of exposure to organophosphate. the susceptibility of larvae was deter ... | 2011 | 21779861 |
| human and environmental factors affecting aedes aegypti distribution in an arid urban environment. | aedes aegypti has reappeared in urban communities in the southwestern u.s.a. in the 1990s after a 40-year absence. in 2003 and 2004, a systematic survey was conducted throughout metropolitan tucson, az, to identify human and environmental factors associated with ae. aegypti distribution within an arid urban area. aedes aegypti presence and abundance were measured monthly using the centers for disease control and prevention enhanced oviposition traps at sampling sites established in a grid at 3- ... | 2011 | 21805845 |
| effectiveness of indoor ultra-low volume application of aqua reslin super during an emergency. | indoor ultra-low volume (ulv) applications of aqua reslin super (permethrin + s-bioallethrin) were carried out using portable solo port 423 sprayers in an urban area of reforma, chiapas, mexico. sprayers were calibrated to discharge a flow rate of 110 ml/min with a dose range of approximately 0.55 to 0.792 mg al/m3 space. entomological evaluation, based on 3 cages per house, each containing 15 sugar-fed, 2-4-day-old aedes aegypti females and placed in hidden locations in 4 randomly selected hous ... | 2011 | 21805852 |
| development of a semi-field system for contained field trials with aedes aegypti in southern mexico. | abstract. development of new genetic approaches to either interfere with the ability of mosquitoes to transmit dengue virus or to reduce vector population density requires progressive evaluation from the laboratory to contained field trials, before open field release. trials in contained outdoor facilities are an important part of this process because they can be used to evaluate the effectiveness and reliability of modified strains in settings that include natural environmental variations witho ... | 2011 | 21813843 |
| an in vivo transfection approach elucidates a role for aedes aegypti thioester-containing proteins in flaviviral infection. | mosquitoes transmit pathogens that cause infectious diseases of global importance. techniques to easily introduce genes into mosquitoes, however, limit investigations of the interaction between microbes and their arthropod vectors. we now show that a cationic liposome significantly enhances delivery and expression of plasmid dna in aedes aegypti and anopheles gambiae mosquitoes. we then introduced the genes for ae. aegypti thioester-containing proteins (aeteps), which are involved in the control ... | 2011 | 21818390 |
| In vitro activation and enzyme kinetic analysis of recombinant midgut serine proteases from the Dengue vector mosquito Aedes aegypti. | ABSTRACT: | 2011 | 21827688 |
| the invaders: phylogeography of dengue and chikungunya viruses aedes vectors, on the south west islands of the indian ocean. | aedes albopictus and aedes aegypti are the two main worldwide arbovirus vectors that have experienced invasion phases. aedes aegypti is a pantropical species that spread centuries ago whereas ae. albopictus started the main wave of invasion in the 1980s. both species have been at various times on the different islands in southwestern indian ocean (swio). this area provides an opportunity to examine the extent to which mosquitoes colonization patterns are influenced by different introductory even ... | 2011 | 21827872 |
| [spatial interpolation of aedes aegypti larvae abundance for locating infestation foci]. | design and implement a surveillance method for locating aedes aegypti infestation foci with the use of larvae traps and spatial interpolation techniques, which facilitate the ongoing estimation of vector abundance in the area by counting the individuals collected in the study area. | 2011 | 21829965 |
| why dengue and yellow fever coexist in some areas of the world and not in others? | urban yellow fever and dengue coexist in africa but not in asia and south america. in this paper, we examine four hypotheses (and various combinations thereof) to explain the absence of yellow fever in urban areas of asia and south america. in addition, we examine an additional hypothesis that offers an explanation of the coexistence of the infections in africa while at the same time explaining their lack of coexistence in asia. the hypotheses we tested to explain the nonexistence of yellow feve ... | 2011 | 21839800 |
| Thermal sensitivity of Aedes aegypti from Australia: empirical data and prediction of effects on distribution. | An understanding of physiological sensitivity to temperature and its variability is important for predicting habitat suitability for disease vectors under different climatic regimes. In this study, we characterized the thermal sensitivity of larval developmental rates and survival in several Australian mainland populations of the dengue virus vector Aedes aegypti. Males developed more rapidly than females, but there were no differences among populations for development time or survival despite p ... | 2011 | 21845954 |
| The wMel Wolbachia strain blocks dengue and invades caged Aedes aegypti populations. | Dengue fever is the most important mosquito-borne viral disease of humans with more than 50 million cases estimated annually in more than 100 countries. Disturbingly, the geographic range of dengue is currently expanding and the severity of outbreaks is increasing. Control options for dengue are very limited and currently focus on reducing population abundance of the major mosquito vector, Aedes aegypti. These strategies are failing to reduce dengue incidence in tropical communities and there is ... | 2011 | 21866159 |
| Successful establishment of Wolbachia in Aedes populations to suppress dengue transmission. | Genetic manipulations of insect populations for pest control have been advocated for some time, but there are few cases where manipulated individuals have been released in the field and no cases where they have successfully invaded target populations. Population transformation using the intracellular bacterium Wolbachia is particularly attractive because this maternally-inherited agent provides a powerful mechanism to invade natural populations through cytoplasmic incompatibility. When Wolbachia ... | 2011 | 21866160 |
| can wolbachia be used to control malaria? | malaria is a mosquito-borne infectious disease caused by plasmodium parasites transmitted by the infectious bite of anopheles mosquitoes. vector control of malaria has predominantly focused on targeting the adult mosquito through insecticides and bed nets. however, current vector control methods are often not sustainable for long periods so alternative methods are needed. a novel biocontrol approach for mosquito-borne diseases has recently been proposed, it uses maternally inherited endosymbioti ... | 2011 | 21881776 |
| biological activity of selected lamiaceae and zingiberaceae plant essential oils against the dengue vector aedes aegypti l. (diptera: culicidae). | the larvicidal activity of hydrodistillate extracts from mentha piperita l. ocimum basilicum l. curcuma longa l. and zingiber officinale l. were investigated against the dengue vector aedes aegypti l. (diptera: culicidae).the results indicated that the mortality rates at 80, 100, 200 and 400 ppm of m. piperita, z. officinale, c. longa and o. basilicum concentrations were highest amongst all concentrations of the crude extracts tested against all the larval instars and pupae of a. aegypti. result ... | 2012 | 21881945 |
| the value of educational messages embedded in a community-based approach to combat dengue fever: a systematic review and meta regression analysis. | the effects of various dengue control measures have been investigated in previous studies. the aim of this review was to investigate the relative effectiveness (re) of different educational messages embedded in a community-based approach on the incidence of aedes aegypti larvae using entomological measures as outcomes. | 2011 | 21886848 |
| natural vertical transmission of dengue viruses by aedes aegypti in bolivia. | the natural transmission of dengue virus from an infected female mosquito to its progeny, namely the vertical transmission, was researched in wild caught aedes aegypti during an important outbreak in the town of santa cruz de la sierra, bolivia. mosquitoes were collected at the preimaginal stages (eggs, larvae and pupae) then reared up to adult stage for viral detection using molecular methods. dengue virus serotypes 1 and 3 were found to be co-circulating with significant higher prevalence in m ... | 2011 | 21894270 |
| costs of dengue prevention and incremental cost of dengue outbreak control in guantanamo, cuba. | to assess the economic cost of routine aedes aegypti control in an at-risk environment without dengue endemicity and the incremental costs incurred during a sporadic outbreak. | 2012 | 21906216 |
| dissemination of metarhizium anisopliae of low and high virulence by mating behavior in aedes aegypti. | dengue is a viral disease transmitted by aedes mosquitoes. it is a threat for public health worldwide and its primary vector aedes aegypti is becoming resistant to chemical insecticides. these factors have encouraged studies to evaluate entomopathogenic fungi against the vector. here we evaluated mortality, infection, insemination and fecundity rates in a. aegypti females after infection by autodissemination with two mexican strains of metarhizium anisopliae. | 2011 | 21906283 |
| Alterations in the Aedes aegypti transcriptome during infection with West Nile, dengue and yellow fever viruses. | West Nile (WNV), dengue (DENV) and yellow fever (YFV) viruses are (re)emerging, mosquito-borne flaviviruses that cause human disease and mortality worldwide. Alterations in mosquito gene expression common and unique to individual flaviviral infections are poorly understood. Here, we present a microarray analysis of the Aedes aegypti transcriptome over time during infection with DENV, WNV or YFV. We identified 203 mosquito genes that were = 5-fold differentially up-regulated (DUR) and 202 genes t ... | 2011 | 21909258 |
| population density, water supply, and the risk of dengue fever in vietnam: cohort study and spatial analysis. | aedes aegypti, the major vector of dengue viruses, often breeds in water storage containers used by households without tap water supply, and occurs in high numbers even in dense urban areas. we analysed the interaction between human population density and lack of tap water as a cause of dengue fever outbreaks with the aim of identifying geographic areas at highest risk. | 2011 | 21918642 |
| Changes in the genetic structure of Aedes aegypti (Diptera: Culicidae) populations in Queensland, Australia, across two seasons: implications for potential mosquito releases. | Diseases transmitted by mosquitoes could be controlled if vector populations were replaced with strains that have reduced vector competency. Such a strategy is being developed for control of dengue virus which is transmitted by Aedes aegypti (L.) (Diptera: Culicidae). Mosquitoes artificially infected with the bacterium, Wolbachia pipientis Hertig, are being assessed as candidates for release at the adult stage with the aim of replacement of the wild population. Wolbachia can reduce the capacity ... | 2011 | 21936318 |
| Mosquito genomics: progress and challenges. | The whole-genome sequencing of mosquitoes has facilitated our understanding of fundamental biological processes at their basic molecular levels and holds potential for application to mosquito control and prevention of mosquito-borne disease transmission. Draft genome sequences are available for Anopheles gambiae, Aedes aegypti, and Culex quinquefasciatus. Collectively, these represent the major vectors of African malaria, dengue fever and yellow fever viruses, and lymphatic filariasis, respectiv ... | 2012 | 21942845 |
| threat of dengue fever and dengue haemorrhagic fever to egypt from travelers. | dengue (df) and dengue hemorrhagic fevers (dhf) are present in urban and suburban areas in the americas, south-east asia, the eastern mediterranean and the western pacific, but dengue fever is present mainly in the rural areas of africa. several factors have combined to produce epidemiological conditions in developing countries in the tropics and subtropics that favour viral transmission by the main mosquito vector, aedes aegypti as the rapid population growth, rural-urban migration, inadequate ... | 2011 | 21980768 |
| co-occurrence patterns of the dengue vector aedes aegypti and aedes mediovitattus, a dengue competent mosquito in puerto rico. | aedes aegypti is implicated in dengue transmission in tropical and subtropical urban areas around the world. ae. aegypti populations are controlled through integrative vector management. however, the efficacy of vector control may be undermined by the presence of alternative, competent species. in puerto rico, a native mosquito, ae. mediovittatus, is a competent dengue vector in laboratory settings and spatially overlaps with ae. aegypti. it has been proposed that ae. mediovittatus may act as a ... | 2011 | 21989642 |
| imaginal discs--a new source of chromosomes for genome mapping of the yellow fever mosquito aedes aegypti. | the mosquito aedes aegypti is the primary global vector for dengue and yellow fever viruses. sequencing of the ae. aegypti genome has stimulated research in vector biology and insect genomics. however, the current genome assembly is highly fragmented with only ~31% of the genome being assigned to chromosomes. a lack of a reliable source of chromosomes for physical mapping has been a major impediment to improving the genome assembly of ae. aegypti. | 2011 | 21991400 |
| Association of human immune response to Aedes aegypti salivary proteins with dengue disease severity. | Dengue viruses (DENV; family Flaviviridae, genus Flavivirus) are transmitted by Aedes aegypti mosquitoes and can cause dengue fever (DF), a relatively benign disease, or more severe dengue haemorrhagic fever (DHF). Arthropod saliva contains proteins delivered into the bite wound that can modulate the host haemostatic and immune responses to facilitate the intake of a blood meal. The potential effects on DENV infection of previous exposure to Ae. aegypti salivary proteins have not been investigat ... | 2012 | 21995849 |
| Adulticidal and repellent properties of indigenous plant extracts against Culex quinquefasciatus and Aedes aegypti (Diptera: Culicidae). | Several diseases are associated to the mosquito-human interaction. Mosquitoes are the carriers of severe and well-known illnesses such as malaria, arboviral encephalitis, dengue fever, chikunguniya fever, West Nile virus, and yellow fever. These diseases produce significant morbidity and mortality in humans and livestock around the world. The adulticidal and repellent activities of crude hexane, ethyl acetate, benzene, chloroform, and methanol extracts of leaf of Eclipta alba and Andrographis pa ... | 2011 | 22009267 |
| Potential impact of a presumed increase in the biting activity of dengue-virus-infected Aedes aegypti (Diptera: Culicidae) females on virus transmission dynamics. | Recently, we showed that infection with dengue virus increases the locomotor activity of Aedes aegypti females. We speculate that the observed increased locomotor activity could potentially increase the chances of finding a suitable host and, as a consequence, the relative biting rate of infected mosquitoes. We used a mathematical model to investigate the impact of the increased locomotor activity by assuming that this activity translated into an increased biting rate for infected mosquitoes. Th ... | 2011 | 22012232 |
| green synthesis of silver nanoparticles for the control of mosquito vectors of malaria, filariasis, and dengue. | a biological method was used to synthesize stable silver nanoparticles that were tested as mosquito larvicides against aedes aegypti, anopheles stephensi, and culex quinquefasciatus. annona squamosa leaf broth (5%) reduced aqueous 1 mm agno₃ to stable silver nanoparticles with an average size of 450 nm. the structure and percentage of synthesized nanoparticles was characterized by using ultraviolet spectrophotometry, x-ray diffraction, fourier transform infrared spectroscopy, and scanning electr ... | 2012 | 22022807 |
| phylogeography of aedes aegypti in argentina: long-distance colonization and rapid restoration of fragmented relicts after a continental control campaign. | aedes (stegomyia) aegypti, the main vector of dengue and yellow fever viruses, is present in all the northern and central provinces of argentina. during 2009, a dengue outbreak spread broadly throughout the country, causing 27,752 infections in 13 provinces. in argentina, little is known about the demographic history of this vector, which suffered a drastic decrease in abundance and distribution during a major control campaign performed in the americas between 1950 and 1960. with the aim of unco ... | 2012 | 22022812 |
| prevalence and insecticide susceptibility of dengue vectors in the district of batticaloa in eastern sri lanka. | unprecedented incidences of dengue have been reported in sri lanka in recent years. the district of batticaloa, which was devastated by the 2004 asian tsunami, is one of the districts affected by dengue. one option to curtail this disease is to implement appropriate vector control measures. a nine-month study was carried out within the batticaloa municipal council limit from april to december 2008. larval collections were conducted fortnightly using conventional ovitraps for nine months covering ... | 2011 | 22028610 |
| [a mathematical model for the chemical control of aedes aegypti (diptera: culicidae) having acquired chemical resistance]. | dengue fever is a common vector-borne disease in tropical and subtropical areas. it is transmitted to humans by the bite of an infected female aedes mosquito. since no vaccines are currently available which can protect against infection, disease control relies on controlling the mosquito population. this work was aimed at modelling such mosquito's population dynamics regarding chemical control of the adult population and its acquired resistance to chemicals. the model was analysed by using class ... | 2010 | 22030690 |
| [knowledge, attitudes and community practice during an outbreak of dengue in a town in colombia, 2010]. | 17 cases of dengue were reported from the town of el playón (7°28'15"-n/73°12'00"-w/altitude 510 masl) during epidemiological study weeks 5-6 and 12-13/2010. the santander department's health secretariat sought outbreak investigation and community knowledge-attitudes-practice (kap) assessment on 16-4-2010 concerning a dengue fever outbreak in the town after an epidemiological surveillance committee had met; this was to strengthen local action regarding aedes aegypti vector promotion-prevention-c ... | 2011 | 22031003 |
| field performance of engineered male mosquitoes. | dengue is the most medically important arthropod-borne viral disease, with 50-100 million cases reported annually worldwide. as no licensed vaccine or dedicated therapy exists for dengue, the most promising strategies to control the disease involve targeting the predominant mosquito vector, aedes aegypti. however, the current methods to do this are inadequate. various approaches involving genetically engineered mosquitoes have been proposed, including the release of transgenic sterile males. how ... | 2011 | 22037376 |
| optimal timing of insecticide fogging to minimize dengue cases: modeling dengue transmission among various seasonalities and transmission intensities. | dengue infection is endemic in many regions throughout the world. while insecticide fogging targeting the vector mosquito aedes aegypti is a major control measure against dengue epidemics, the impact of this method remains controversial. a previous mathematical simulation study indicated that insecticide fogging minimized cases when conducted soon after peak disease prevalence, although the impact was minimal, possibly because seasonality and population immunity were not considered. periodic out ... | 2011 | 22039560 |
| Factors influencing the seasonal abundance of Aedes (Stegomyia) aegypti and the control strategy of dengue and dengue haemorrhagic fever in Thanlyin Township, Yangon City, Myanmar. | From June 2006 to May 2007, mosquito surveys were conducted in Thanlyin Township, Yangon City, Myanmar, to determine factors influencing the abundance of Aedes aegypti (Stegomyia aegypti) during the rainy season. Both the biological and environmental factors were included in this study. Increase in the hatchability of egg, larval survival rate, the shortened larval life-span and increased pupation rates supplemented by rainfall (i.e. continuous flooding of the containers, stimulate the ... | 2011 | 22041749 |
| a novel herbal formulation against dengue vector mosquitoes aedes aegypti and aedes albopictus. | the objective of this study was to develop a herbal formulation to control dengue vector mosquitoes. ponneem, a novel herbal formulation prepared using the oils of neem (azadirachta indica), karanj (pongamia glabra) and their extracts, was tested for larvicidal, ovicidal and oviposition deterrent activities against aedes aegypti and aedes albopictus at 1, 0.5, 0.3 and 0.1 ppm concentrations. cent percent larvicidal and ovicidal activities were observed at 0.1 ppm in the two mosquito species unde ... | 2011 | 22042505 |
| challenges in estimating insecticide selection pressures from mosquito field data. | insecticide resistance has the potential to compromise the enormous effort put into the control of dengue and malaria vector populations. it is therefore important to quantify the amount of selection acting on resistance alleles, their contributions to fitness in heterozygotes (dominance) and their initial frequencies, as a means to predict the rate of spread of resistance in natural populations. we investigate practical problems of obtaining such estimates, with particular emphasis on mexican p ... | 2011 | 22069506 |
| global cross-talk of genes of the mosquito aedes aegypti in response to dengue virus infection. | the mosquito aedes aegypti is the primary vector of dengue virus (denv) infection in humans, and denv is the most important arbovirus across most of the subtropics and tropics worldwide. the early time periods after infection with denv define critical cellular processes that determine ultimate success or failure of the virus to establish infection in the mosquito. | 2011 | 22102922 |
| modeling spatio-temporal risk changes in the incidence of dengue fever in saudi arabia: a geographical information system case study. | the aim of this study was to use geographical information systems to demonstrate the dengue fever (df) risk on a monthly basis in jeddah, saudi arabia with the purpose to provide documentation serving to improve surveillance and monitor the aedes aegypti mosquito vector. getis-ord gi* statistics and a frequency index covering a five-year period (2006-2010) were used to map df and model the risk spatio-temporally. the results show that monthly hotspots were mainly concentrated in central jeddah d ... | 2011 | 22109865 |
| wolbachia strain wmel induces cytoplasmic incompatibility and blocks dengue transmission in aedes albopictus. | wolbachia inherited bacteria are able to invade insect populations using cytoplasmic incompatibility and provide new strategies for controlling mosquito-borne tropical diseases, such as dengue. the overreplicating wmelpop strain was recently shown to strongly inhibit the replication of dengue virus when introduced into aedes aegypti mosquitoes, as well as to stimulate chronic immune up-regulation. here we show that stable introduction of the wmel strain of drosophila melanogaster into aedes albo ... | 2011 | 22123944 |
| wolbachia induces reactive oxygen species (ros)-dependent activation of the toll pathway to control dengue virus in the mosquito aedes aegypti. | wolbachia are maternally transmitted symbiotic bacteria that can spread within insect populations because of their unique ability to manipulate host reproduction. when introduced to nonnative mosquito hosts, wolbachia induce resistance to a number of human pathogens, including dengue virus (denv), plasmodium, and filarial nematodes, but the molecular mechanism involved is unclear. in this study, we have deciphered how wolbachia infection affects the aedes aegypti host in inducing resistance to d ... | 2011 | 22123956 |