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initial management of cutaneous malignant melanoma.appropriate initial surgical management of primary cutaneous malignant melanoma is important since no effective treatment exists once the tumour metastasizes. the author reviews methods of initial treatment, excisional biopsy with adequate margins being the most common. he also reports results from a questionnaire survey on the type of microstaging used at hospitals across canada. two thirds of the pathologists who responded to the questionnaire preferred to use both clark's and breslow's method ...20133719498
reproducibility of a histopathologic grading system for adult soft tissue sarcoma.tumor grade has been proposed as an essential factor in the staging of patients with soft tissue sarcomas. in a previous study, a histopathologic grading system using the evaluation of tumor differentiation, mitosis count, and tumor necrosis was described. the current study was conducted to test its reproducibility. the pathologic sections of 25 soft tissue sarcomas were submitted to a study group composed of 15 pathologists who had not been involved in the development of the grading system. the ...20133719523
concurrent familial myeloma in northern ireland.three families are presented containing two members of each family with myeloma over a 13-year period in northern ireland. in all three families, the disease was concurrent, and the first reported cases of concurrent myeloma in a father and son and also identical twins are included. this incidence represents a greater frequency than would be expected and gives credence to the idea of an etiologic agent in this disease.20133719534
prognostic factors in laryngeal carcinoma. a multifactorial study of 416 cases.the prognostic significance of 20 clinical and histologic parameters was evaluated in a series of 416 laryngeal carcinomas treated between 1969 and 1981 at the hospital de santa cruz y san pablo, barcelona, spain. clinical follow-up ranged from 2 to 13 years. the variables considered were: age, smoking habits, previous laryngeal disease, duration of clinical symptoms, motility of vocal cords, interval between diagnosis and treatment, postoperative infection, topographic location of the tumor, pr ...20133719558
influence of the application mode of n-[4-(5-nitro-2-furyl)-2-thiazolyl]-formamide on the localization of its carcinogenic expression in female nmri-mice.the administration of n-[4-(5-nitro-2-furyl)-2-thiazolyl]-formamide fanft) by gavage to female nmri-mice resulted in a high incidence of neoplasms of the forestomach. from 117 effective animals which were pooled from 3 dosed groups, 30 squamous cell carcinomas and 26/117 papillomas of the forestomach were diagnosed. only 5/117 neoplasms of the urinary bladder occurred. the average cumulative dose administered was 1180 mg/mouse, and the mean latent period for the induction of forestomach tumours ...19863719571
phase ii eastern cooperative oncology group study of spirogermanium in previously treated lymphoma. 20133719586
combination chemotherapy with dacarbazine and vindesine in the treatment of metastatic malignant melanoma. 20133719588
destruction of both extensive local recurrent and primary breast cancer with topical aqueous 5-fu: a clinical observation. 20133719590
enhancement of defective monocyte function during immunotherapy with recombinant interferon.the influence of immunotherapy with high dose (50 x 10(6) units/m2) recombinant leukocyte a interferon on blood monocyte functions was studied in eight patients with bronchogenic carcinoma. monocyte chemotactic responsiveness (mcr) was initially depressed (9.8 +/- 1.6 cells/field) compared to healthy controls (17.6 +/- 5.1 cells/field), p less than 0.01. recombinant interferon was administered three times weekly, and after 7 days a significant improvement in chemotaxis was observed (16.6 +/- 3.0 ...20133719594
morphogenesis of sclerotome and neural crest in avian embryos. in vivo and in vitro studies on the role of notochordal extracellular material.the distribution of sclerotome and neural crest cells of avian embryos was studied by light and electron microscopy. sclerotome cells radiated from the somites towards the notochord, to occupy the perichordal space. neural crest cells, at least initially, also entered cell-free spaces. at the cranial somitic levels they moved chiefly dorsal to the somites, favouring the rostral part of each somite. these cells did not approach the perichordal space. more caudally (i.e. trunk levels), neural cres ...19863719666
[the hageman factor and its active forms. separation, methods of determination and its characteristics]. 20133719709
[summer-vacation hospitalization of obese children]. 20133719814
glomerular permeability. 19863720198
[laboratory monitoring of anticoagulant and thrombolysis treatment]. 20133720592
[clinical chemistry of the cerebrospinal fluid]. 20133720593
seasonal distribution of facultatively enteropathogenic vibrios (vibrio cholerae, vibrio mimicus, vibrio parahaemolyticus) in the freshwater of the elbe river at hamburg.between june 1981 and december 1982 the incidence of vibrio cholerae, v. mimicus and v. parahaemolyticus was determined at two sampling sites on the elbe river at hamburg. a total of 183 strains was isolated from 147 water samples. of these, 107 belonged to non-01 v. cholerae (ten strains producing a cholera-like enterotoxin); 33 were identified as v. mimicus, including two enterotoxin producers; 42 strains were kanagawa-negative cultures of v. parahaemolyticus; and one was v. fluvialis. the hig ...19863722029
comparative clinical evaluation of aztreonam versus aminoglycosides in gram-negative septicaemia.we have conducted an open randomized comparison of aztreonam versus an aminoglycoside in 100 adult, non-granulocytopenic patients with suspected or proven aerobic gram-negative septicaemia. forty-three patients with negative blood cultures, with blood isolates resistant to the antibiotic used, or who died within the first 24 h were excluded. of the 57 evaluable patients, 31 received aztreonam and 26 aminoglycoside (13 gentamicin and 13 tobramycin). patients in both groups were comparable with re ...20133722035
hereditary, eruptive, primary cutaneous malignant melanomas: a previously undescribed entity. 20133722578
abamectin: toxicity to house flies (diptera: muscidae) resistant to synthetic organic insecticides. 20133722588
from the national institute of allergy and infectious diseases. summary of the 21st united states-japan joint cholera conference. 19863722875
thyroid hormone administration in irradiated patients.in a recall clinic for patients at risk for thyroid carcinoma due to a history of radiation in infancy or childhood, a group of patients were randomly offered prospective suppressive l-thyroxine therapy and matched to a radiated nontreated group. with an average of more than two years' follow-up, the thyroid hormone-treated radiated group developed fewer nodules and abnormalities to palpation and also had a statistically significant lessening of minimal palpable abnormalities compared to the non ...20133724174
left atrial catheter complications. 20093724223
isolation and characterization of apolipoprotein b-100. 19863724504
herpes simplex oesophagitis in young children.herpes simplex oesophagitis is usually associated with debilitated, traumatized or immunologically-compromised hosts. we report here two cases of severe self-limiting oesophagitis in immunologically competent young children that were caused by herpes simplex type 1. this diagnosis should be considered in the differential diagnosis of acute severe pain on swallowing in children for whom oral and pharyngeal pathology have been excluded.20133724605
management and outcome of children with congenital hypothyroidism detected on neonatal screening in south australia.thirty-eight congenitally hypothyroid children who were detected in a neonatal screening programme have been treated for a mean period of 3.8 years (range, 0.5-8.5 years) by the maintenance of the free thyroxine index in the upper normal range as the main determinant of the dose of thyroxine. only excessive elevation of, or serial rises in, thyroid stimulating hormone (tsh) level influenced the dose of thyroxine. this treatment strategy, which aims to avoid the potentially adverse effects of thy ...20133724623
evaluation of possible interactions between ethanol and trazodone or amitriptyline.the pharmacodynamic effects of single doses of trazodone (100 mg), amitriptyline (50 mg) or placebo either alone or with ethanol (0.5 ml/kg) were investigated in 6 healthy volunteers in a double-blind crossover study. plasma concentrations of the drugs and ethanol were also measured. pharmacodynamic tests were critical flicker fusion frequency threshold (cff), choice reaction time (crt), manual dexterity, a digit span test and visual analogue scales. blood ethanol concentrations were not influen ...20133725002
[conservative treatment in splenic injuries. results of a follow-up in patients with autotransplants]. 20133725057
[intracranial aneurysms and subarachnoid hemorrhage in children and adolescents].42 cases concerning symptomatic intracranial circulation aneurysms and spontaneous sah have been observed by the authors during the period 1965-1984; 37 of them were treated from 1970 on. this group represents 2.6% in the number of patients treated for sah during the above mentioned period in the series of pavia and verona neurosurgery. in 7 cases angiography did not evidence any malformation responsible for the hemorrhage. these cases have been defined as "sine materia" sah. in 33 cases was doc ...20113725140
ethnic differences in the reactions to drugs and xenobiotics. the metabolism and toxicity of primaquine. 19863725763
[measurement of the friction coefficient of different lubricated granules]. 20133725807
another dimension for informed consent. 20133725943
[status of the uterine mucosa during long-term intrauterine contraception].structural, functional, and morphological parameters of the endometrium were examined during and after long-term intrauterine contraception. the study included 638 women, aged 19-48, who had been using a lippes' loop for .4-12 years; the control group consisted of 96 women who were planning to use intrauterine contraception. endometrial samples were treated with a 10% formalin solution, histologically processed, and embedded in paraffin. the sections were stained with a hematoxylineosin reagent ...20133726613
a prospective randomized study of moxalactam versus gentamicin and clindamycin in penetrating abdominal trauma.we conducted a randomized, prospective study of moxalactam versus gentamicin plus clindamycin in 42 patients with penetrating abdominal trauma. patients were randomized to receive intravenously either 2 grams of moxalactam every 12 hours or 80 milligrams of gentamicin every eight hours and 600 milligrams of clindamycin every six hours. antibiotics were administered preoperatively and continued for a minimum of five days if hollow viscus injury occurred. for those without hollow viscus injury, on ...20103726718
a study of head lice among primary schoolchildren in kenya.of 1270 schoolchildren (651 girls and 619 boys) from 33 urban and rural primary schools in different regions of kenya who were examined for head lice, 17.1% were infested (8% with living lice or nits, 9.1% with dead nits). the over-all difference between infestation rates in urban and rural schools was not significant, but there was considerable variation in the five different regions selected. infestation was not sex-related. infestation rates tended to be higher in older children and in childr ...19863726995
epidemiological differences between cholera due to multiple antibiotic resistant and multiple antibiotic sensitive vibrio cholerae infection.the appearance of cholera caused by multiply antibiotic resistant vibrio cholerae in bangladesh provided an opportunity to compare epidemiological features of infection caused by resistant and by sensitive v. cholerae. a prospective study was carried out using 46 families of hospital in-patient cholera cases due to resistant v. cholerae and 11 families of hospital cases due to sensitive v. cholerae and nine cases of cholera due to resistant and six cases due to sensitive v. cholerae detected in ...19863726999
directionality and alignment of the foveal receptors, assessed with light scattered from the human fundus in vivo.the directionality of the foveal receptors of four subjects is assessed with a technique based on light scattering, and a psychophysical technique. the width and orientation of the absorbance diagram (difference between the scattering diagram in a bleached and unbleached state of the visual pigment) are compared with the stiles-crawford function. results show that the directionality in the scattering diagram points into approximately the same direction as the s-c function, but the width of the s ...19863727414
antibodies to cholera toxin synthetic peptides of increasing size and their reactivity with related toxins.the role of the size of synthetic peptides in their immunological cross-reactivity with the parent native protein, was investigated using the cholera toxin system. the results show that elongation of a peptide may affect the reactivity of the antibodies it elicits in either positive or negative directions. thus, elongation by six amino acid residues of each of two peptides of cholera toxin that were incapable of inducing cross-reactive antibodies with the parent protein (ctp2a and ctp5) converte ...19863727761
using emg-biofeedback in the treatment of facial paralysis. 20133727987
a class of cleavable heterobifunctional reagents for thiol-directed high-efficiency protein crosslinking: synthesis and application to the analysis of protein contact sites in mammalian ribosomes.the synthesis of a new class of cleavable crosslinking reagents is described. the primary function, a ring-substituted maleimide, binds selectively and very efficiently at low ph to cysteine-containing protein sequences. at increased ph the secondary function, an n-hydroxysuccinimide ester of a ring-attached carboxyl group, becomes reactive against adjacent amino groups. the spacer, azobenzene, is readily cleaved by reduction with dithionite provided that a hydroxyl group is included in the ring ...20133728979
a quantitative test for measuring reactivity to cold by the digital plethysmograph technique: application to 66 control subjects and 65 patients with raynaud's phenomenon.the authors have developed a vascular reactivity test to cold using the digital plethysmograph technique with a mercury strain gauge. three types of arterial reactivity were determined: local reactivity after immersion of the hand in 11 degrees c water, general reactivity after thorax ventilation, and cumulative reactivity associating both of these cooling modes. the method is based on measurement of the digital plethysmographic signal expressed as a ratio of a reference warm amplitude obtained ...20123729069
critique of various dietary regimens in the management of food allergy. 20123729082
oral analgesia for treatment of painful crisis in sickle cell anemia.a therapeutic plan that emphasized oral narcotic analgesia was instituted for the treatment of painful crisis of sickle cell anemia. of the 100 adult sickle cell syndrome patients registered at north central bronx hospital, 15 were identified as using the emergency department facilities three or more times per year. this "frequent user" patient population was tracked in their hospital and drug usage patterns during the first full year of the oral protocol and compared to their own patterns durin ...20123729099
factors affecting bronchial blood flow through bronchopulmonary anastomoses in dogs.most of the bronchial arterial blood flow (qbr) drains through bronchopulmonary anastomoses into the pulmonary circulation, and the remainder goes into the systemic venous system via the bronchial veins. we studied the relationship between blood flow through bronchopulmonary anastomoses, and alveolar pressure and pulmonary vascular pressures as well as hydrostatic pressure in the bronchial veins in 10 adult dogs. the pulmonary artery and vein of the experimental left lower lobes (lll) of open-ch ...19863729165
covert splenic abscess: a continuing challenge.although splenic abscess is a rare cause of intra-abdominal sepsis, the mortality rate remains high especially in patients with silent or covert lesions. the clinical presentation and course of five patients with overt splenic abscess and seven patients with covert splenic abscess seen during a thirty year period were analyzed. average age of patients with overt lesions was 44.5 years. direct extension from a contiguous source, hematogenous spread from a distant site (metastatic) and trauma comp ...20133729173
anticandidal activities of terconazole, a broad-spectrum antimycotic.terconazole is a new triazole ketal derivative with broad-spectrum in vitro and in vivo antifungal activities. this study further characterizes the effects of terconazole in vitro on yeast cell growth, viability, and morphology. terconazole inhibited the growth of candida albicans atcc 44859 in a concentration-related manner, but with modest effects noted at levels from 10(-8) to 10(-5) m when the yeast was grown on media favoring the cell form. the inhibitory potency of terconazole on yeast cel ...19863729366
isolation of non-o1 vibrio cholerae serovars from surface waters in western colorado.non-o1 vibrio cholerae was isolated from rivers, creeks, washes, irrigation canals, and ditches in western colorado during the summer of 1985. the organism occurred in fresh water (less than or equal to 5 mmol of na+ per liter) as well as in water of higher salinity (approximately equal to 17 mmol per liter). sixteen serovars of non-o1 v. cholerae were sixteen serovars of non-o1 v. cholerae were identified among the environmental isolates. all of the isolates were cytotoxic to y-1 mouse adrenal ...19863729397
segmental portal hypertension.isolated obstruction of the splenic vein leads to segmental portal hypertension, which is a rare form of extrahepatic portal hypertension, but it is important to diagnose, since it can be cured by splenectomy. in a review of the english literature, 209 patients with isolated splenic vein obstruction were found. pancreatitis caused 65% of the cases and pancreatic neoplasms 18%, whereas the rest was caused by various other diseases. seventy-two per cent of the patients bled from gastroesophageal v ...20113729585
segmental portal hypertension.isolated obstruction of the splenic vein leads to segmental portal hypertension, which is a rare form of extrahepatic portal hypertension, but it is important to diagnose, since it can be cured by splenectomy. in a review of the english literature, 209 patients with isolated splenic vein obstruction were found. pancreatitis caused 65% of the cases and pancreatic neoplasms 18%, whereas the rest was caused by various other diseases. seventy-two per cent of the patients bled from gastroesophageal v ...20113729585
spatial representations in mathematically and in artistically gifted children. 20133730273
the sodium cycle. iii. vibrio alginolyticus resembles vibrio cholerae and some other vibriones by flagellar motor and ribosomal 5s-rna structures.an electron microscopic study of the basal bodies of the vibrio albinolyticus flagellum revealed a four-disc structure. the diameters of the two discs localized closer to the cytoplasmic membrane proved to be about 2-fold shorter than those of the two others. in this respect the basal body of v. alginolyticus resembles very much that of v. cholerae described by ferris and co-workers. the sequence of the v. alginolyticus ribosomal 5s-rna showed that it is similar to those of v. cholerae, v. harve ...19863730372
[prevention of ischemic and re-oxygenation arrhythmias and heart fibrillation using the antioxidant ionol].the effect of a synthetic antioxidant, ionol (2,4-ditrebutyl-4-methylphenol) on cardiac arrhythmias induced by 10-minute occlusion of the left coronary artery followed by 5 minutes of reperfusion (rp) was investigated. the study was performed on male wistar rats, 250-300 g body weight. the animals were ventilated with room air under urethan anesthesia. rp induced more severe ventricular arrhythmias than ischemia (is). during rp ventricular fibrillation developed in 12 and during is in 2 out of 2 ...19863730544
[prevention of ischemic and re-oxygenation arrhythmias and heart fibrillation using the antioxidant ionol].the effect of a synthetic antioxidant, ionol (2,4-ditrebutyl-4-methylphenol) on cardiac arrhythmias induced by 10-minute occlusion of the left coronary artery followed by 5 minutes of reperfusion (rp) was investigated. the study was performed on male wistar rats, 250-300 g body weight. the animals were ventilated with room air under urethan anesthesia. rp induced more severe ventricular arrhythmias than ischemia (is). during rp ventricular fibrillation developed in 12 and during is in 2 out of 2 ...19863730544
radiation-induced stenosis of the left main coronary artery.a case of isolated left main coronary artery stenosis ten years following irradiation of the mediastinum for hodgkin's disease is presented. aortic biopsies were consistent with changes suggestive of radiation arteritis.20133731265
proposed mechanism for depression of maximal rate of left ventricular pressure fall (peak negative dp/dt) during regional myocardial ischemia.to investigate the mechanism of the depression of left ventricular (lv) peak negative dp/dt during acute regional ischemia, studies were performed in seven open-chest anesthetized dogs. regional lv wall thickness was measured with ultrasonic crystals in both an ischemic and a normally perfused segment. ischemia was produced by complete occlusion of the left anterior descending coronary artery for 30 seconds. within 10 seconds of ischemia, premature thinning of the ischemic wall developed, which ...19863731266
[autonomic disturbance in cerebellar degeneration--a comparative study between olivopontocerebellar degeneration and late cortical cerebellar atrophy]. 20133731629
[magnetic resonance imaging of carbon monoxide poisoning in chronic stage]. 20123731631
glucose-induced alterations in nerve metabolism: a reply. 20133731998
spinal cord degeneration following general anaesthesia in a shire horse. 19863732243
theoretical analysis of the flux control properties of a substrate cycle.substrate cycles are able to increase the flux control of a non-equilibrium reaction in a wide range of situations related to the effects of the metabolites involved in the cycle on the reaction producing them. no limit exists for that amplification if appropriate conditions are attained if those effects are positive. in all cases, the ratio between the rate of the reverse reaction and the net flux through the pathway plays an important role in defining the final amplification.20133732263
balancing quality and cost: a public decision-making process. 20133732644
[esophageal scintigraphy and ph measurement in asthmatic adults suspected of having gastroesophageal reflux].fifty-five adults with asthma were explored by gastroesophageal scintigraphy (ges) and ph monitoring (3 postprandial hours, 12 nocturnal hours). for their asthma, all patients received theophylline twice a day. associated digestive symptomatology led to investigations for gastroesophageal reflux (ger). twelve hours ph monitoring, the reference method, was validated in 13 normal volunteers. during 12 hr ph monitoring, 4 criteria were studied: number of ger, percentage of time at ph 4, number of g ...20123732745
heterotic and maternal effects in l and s growth strain rats: ii. body weight gains, feed consumption and feed efficiency.a diallel cross between two strains of rats from the same genetic source, that vary greatly in body size, was made in order to evaluate the differences in individual gain, feed consumption and feed efficiency (gain/feed) from 4 to 15 wk of age. significant paternal, maternal and sex effects were evident for all weekly gains and feed consumption. these effects were not significant for feed efficiency. offspring of large line (l) rats grew faster and consumed more feed than offspring of small line ...19863732861
pathologist and pulmonologist: ever the two shall meet? 20093733067
factors affecting the adsorption of choleraphage phi 149 to its host vibrio cholerae 154. 19863733181
effect of food on bioavailability of metronidazole from sugar-coated tablets having different dissolution rates in subjects with low gastric acidity.the effect of food on the bioavailability of metronidazole from three commercial sugar-coated tablets varying markedly in drug dissolution behavior relative to ph was determined after oral administration in healthy male subjects with low gastric acidity. four subjects, whose gastric acidities were evaluated as low (hypo- or anacidity) by using a non-intubation method (gastrotest tablets administration method), received, in a cross-over fashion, a single 250 mg dose in sugar-coated tablet during ...20133733276
clinical applications of yttrium filters for exposure reduction. 20133733390
plasmid trimethoprim resistance in vibrio cholerae: migration of the type i dihydrofolate reductase gene out of the enterobacteriaceae.two strains of vibrio cholerae biotype el tor were isolated in tanzania. each possessed a single resistance plasmid of 113 kbases belonging to the c incompatibility group. both plasmids conferred resistance to sulphamethoxazole, ampicillin, streptomycin, chloramphenicol, tetracycline and trimethoprim. they are the first plasmids derived from v. cholerae strains, isolated in southern africa, to confer trimethoprim resistance. the trimethoprim resistance resulted from the plasmid-mediated producti ...19863733590
rapid and sensitive high-performance liquid chromatographic assay for metformin in plasma and urine using ion-pair extraction techniques. 20133734008
liquid chromatographic method for the determination of debrisoquine and its 4-hydroxy metabolite in human urine. 19863734009
diagnosis and treatment of chalazia.a patient with recurrent chalazia is described. this patient also had acne rosacea. the clinical and histologic characteristics of chalazia are described. in addition, therapy for chalazia is presented, with emphasis being given to conservative therapy.20133734179
cine-computed tomography of ebstein anomaly.a case of ebstein anomaly is reported, and the diagnostic potential of cine-ct in assessing the magnitude of the anatomic changes and the presence of right to left intracardiac shunting is evaluated.20133734206
the biology of basal cell carcinomas--a revisit and recent developments.this paper will review some of the present information on the biology of basal cell carcinoma. recent developments include a better understanding of the basement membrane components surrounding the tumor nodules, as well as identifying the most actively dividing cells in solid basal cell carcinoma by autoradiographic techniques. the implications of a recently developed animal model will also be discussed.20133734233
basal cell carcinoma with eccrine differentiation (eccrine epithelioma).basal cell carcinoma with eccrine differentiation is an invasive, slow-growing tumor that usually occurs on the scalp. the histopathologic findings include basaloid epithelial elements, cystic spaces, and a fibrous or myxomatous stroma. the patient described in this report demonstrated epithelial elements with marked similarity to eccrine ducts. mohs micrographic surgery, by virtue of the large number of frozen sections that are examined, provides an ideal way to study the characteristics of thi ...20133734234
pancreatobiliary duct anatomy and alcoholic pancreatitis. 20133734371
timed overnight sodium and potassium excretion and blood pressure in steel workers in north china.three timed overnight urinary sodium (na), potassium (k) and creatinine measurements, standardized to 8 h, as well as three blood pressures on corresponding consecutive days were obtained on a sample of 90 steel workers (40 men, 50 women) aged 34-56 years in beijing, north china. for three indices of electrolyte excretion - absolute na and k output/8 h, na:k ratio and 8 h creatinine output - the ratios of intra- to inter-individual variations were less than 1.0 for men, but higher for women in c ...20133734452
[prevention of mitral stenosis in the repair of complete atrioventricular canal, by preoperative 2-d echocardiographic evaluation of the lateral leaflet]. 20133734499
risk of hypoventilation in premature infants in car seats.we examined 30 newborn infants for respiratory compromise before, during, and after placement in a recommended car seat restraining device. twelve infants were premature with a history of apnea, eight were premature without known apnea, and 10 were born at term. both premature groups had significant decreases in oxygen saturation while in the car seat (p less than 0.01) and more frequent desaturation episodes less than 80% (p less than 0.001). premature infants with a history of apnea had more b ...20133734961
role of theophylline in pathogenesis of necrotizing enterocolitis. 20133734972
fox shield treatment of the ugh syndrome.the uveitis-glaucoma-hyphema (ugh) syndrome has been described with all types of intraocular lenses. the usual forms of therapy include miotics, mydriatics, steroids, antiglaucomatous medications, laser therapy, and surgical explanation. i describe five patients in whom the ugh syndrome resolved after long-term fox shield treatment to prevent nocturnal hand-eye trauma.20133735123
anxiety-proneness and coronary heart disease. 20133735182
heat illness. a report of 45 cases from hong kong.during the summer of 1985, 45 soldiers with heat illness were admitted to the british military hospital, hong kong. twelve had severe heat stroke, the remainder heat exhaustion. this paper discusses the management and prevention of heat illness in the military context.20133735192
structure and x-ray amino acid sequence of a bacteriochlorophyll a protein from prosthecochloris aestuarii refined at 1.9 a resolution.the structure of the water-soluble bacteriochlorophyll a protein (bchl protein) from the green photosynthetic bacterium prosthecochloris aestuarii has been refined at 1.9 a resolution to a crystallographic residual of 18.9%. the refinement was carried out without knowledge of the amino acid sequence and has led to an "x-ray sequence". the structure consists of seven bchl molecules enclosed within a protein "bag" and the refinement supports the general conformation of the molecule described previ ...19863735428
serum chemistry and evidence of renal failure in the north atlantic fin whale population.serum electrolytes, urea nitrogen, creatinine, albumin and globulin were studied in fin whales (balaenoptera physalus) caught by commercial whalers in the north atlantic (denmark strait area). blood samples were obtained by catchment or cardiac puncture within 5-15 min of death and analyzed using automated spectrophotometric methods and flame photometry. osmolality was determined for two serum samples by a vapor pressure method. linear regressions determined for each measured serum variable vs. ...20133735585
effects of forskolin and prostaglandin e1 on leukotriene c- and d-induced plasma exudation in the rat skin.leukotriene c and d markedly enhanced plasma exudation in rat skin, using [131i]-labeled human serum albumin ([131i]-hsa) to measure vascular permeability. the adenylate cyclase activator forskolin only slightly increased plasma exudation, while markedly potentiating the leukotriene response. prostaglandin e1 increases plasma exudation in rat skin, but appears to act by a different mechanism than leukotrienes, since the responses to combinations of prostaglandin and leukotrienes are synergistic ...19863736323
treatment of alcohol withdrawal. 20133736494
pha responsiveness and adherent cell-lymphocyte interactions in patients with advanced malignant tumors of the ovary prior to treatment and during chemotherapy.dna synthesis in cultures of pha-stimulated blood mononuclear cells from patients with advanced malignant tumors of the ovary before treatment was significantly reduced and responses of lymphocytes alone were, on an average, 40% lower than in control subjects. adherent cells were found to suppress the pha response of autologous lymphocytes from 6/12 patients before treatment, 4/18 patients during chemotherapy and only in 2/19 control subjects. the net effects of adherent cell-lymphocyte interact ...20133736722
terpene hydrocarbons in pimpinella anisum l.the essential oil of anise (fruits and shoots) was investigated focusing on the composition of the hydrocarbon fraction. several sesquiterpenes were identified by gc-ms and the relative composition of the fractions was established by gc analysis. gamma-himachalene and the diterpene neophytadiene were isolated by tlc and column chromatography at low temperatures. their structures were determined by ms and nmr including 1h-1h correlated cosy and noe experiments.20133737372
secondary structure model for mouse beta maj globin mrna derived from enzymatic digestion data, comparative sequence and computer analysis.a model for the secondary structure of mouse beta maj globin messenger rna is presented based on enzymatic digestion data, comparative sequence and computer analysis. using 5'-32p-end-labeled beta globin mrna as a substrate, single-stranded regions were determined with s1 and t1 nucleases and double-stranded regions with v1 ribonuclease from cobra venom. the structure data obtained for ca. 75% of the molecule was introduced into a computer algorithm which predicts secondary structures of minimum ...19863737415
[cholera in fribourg. apropos a case].a 41-year-old man from cameroon was admitted to the hospital of fribourg (switzerland) for watery diarrhea 3 months after cholera vaccination. stool cultures were positive for vibrio cholerae, biotype el tor. treatment consisted of rehydration (up to 9 litres per day) and correction of metabolic acidosis. no antibiotics were administered. the diagnosis of cholera should be considered in the presence of watery diarrhea in travellers or immigrants from countries suffering from the pandemic, even t ...19863738456
duties, fears and physicians.this article deals with the physician's fear of contagion using aids as a paradigm. it deals with this in four ways: it examines the concepts of duty, fear and courage in their medical setting; it deals with the historical aspects of the problem; it analyzes the role of social contract and professionalism; and it develops a viewpoint of the physician's obligation based on these considerations and predicated on a view of professionalism and social contract.20133738560
measles-associated diarrhoea in northeastern thailand.a significant proportion of the illness and death of diarrhoeal diseases in the developing world is estimated to be due to the diarrhoea associated with measles. during february 1983-january 1984 a prospective study of measles in a hospital in northeastern thailand was conducted. a total of 550 cases of measles were studied. diarrhoea was the most frequent complication of measles, occurring in 233 cases (42.4%). the largest proportion (46.2%) of cases with diarrhoea occurred in may-july. childre ...19863738607
[an outbreak of ornithosis. the military camp in porsanger in 1982]. 20133738872
establishment of passive hemagglutination assay (pha) system for anti-hbc in plasma.a sensitive and specific assay system for anti-hbc, the passive hemagglutination (pha) method, has been established. the reactivity of pha cells prepared by conjugating purified recombinant hbcag-particles with fixed sheep blood cells (srbc) was highly specific to monoclonal- and polyclonal anti-hbc iggs. the sensitivity of pha method was higher than that of radioimmunoassay (ria). however, uncertainty for the positivity of anti-hbc still remained in plasma with the pha titers lower than 2(5). a ...19863738912
virulence mechanisms associated with clinical isolates of non-o1 vibrio cholerae.twenty one isolates of non-o1 v. cholerae from patients with diarrheal illness were examined for the presence of potential virulence mechanisms. the motile strains (90%) produced cell-associated mannose-sensitive hemagglutinins which reacted with human group o, chicken, sheep and rabbit erythrocytes. motile isolates also attached to embryonic intestinal epithelial cells (atcc 407), and the adherence was not inhibited by the presence of 1% d-mannose. all vibrio isolates hemolyzed sheep erythrocyt ...19863739461
interference with pacemaker function by cardiokymographic testing. 20133739930
interstitial deletion of the short arm of chromosome 3 (3p14).deletions of 3p usually involve the terminal portion (3p25). an interstitial deletion of a proximal 3p segment (3p14) was detected at amniocentesis. the clinical and cytogenetic characteristics of this case and of three previously published cases are reviewed. cardiovascular and gastrointestinal malformations have not been reported before in association with this particular chromosome abnormality.19863740098
pulmonary hypertension in an 18-year-old girl with cholesteryl ester storage disease (cesd) 20133740103
pharmacokinetics of nalbuphine during parturition.nalbuphine hydrochloride (nubain) is a relatively new agonist-antagonist analgesic, chemically related to both oxymorphone and naloxone, which can be used as a systemic obstetric analgesic. after intravenous administration to six patients in labor at term, serial maternal serum specimens were obtained and assayed for their nalbuphine concentration. the maternal disposition of nalbuphine followed a two-compartment pharmacokinetic model, with an initial distribution phase of 4 to 20 minutes and a ...20083740151
large perilymph fistulas.perilymph fistulas may manifest themselves either by otologic symptoms, as in cases of small fistulas, or primarily through neurologic symptoms, as with large fistulas. a case history is presented of a 3-year-old girl with recurrent bouts of meningitis who was found to have a large perilymph fistula. she had a right undeveloped cochlea and labyrinth, as well as multiple defects of the medial wall of her middle ear. the only way of preventing the recurrent bouts of bacterial meningitis in cases o ...19863740237
pili trianguli et canaliculi: a nonfamilial case with eyebrow and eyelash involvementment. 20133740896
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