Publications
| Title | Abstract | Year Filter | PMID(sorted ascending) Filter |
|---|
| listeriosis following shigellosis. | in 1987 an outbreak of illness due to listeria monocytogenes occurred in philadelphia. in contrast to previously studied outbreaks, no source of infection or vehicle of transmission could be identified, and several listerial strains were found to be involved. a hypothesis that was developed and eventually published suggests that clinical listeriosis may occur when individuals who are asymptomatic for listerial infection but whose gastrointestinal tract has been colonized by listeria organisms be ... | 1991 | 1962099 |
| distinction between 'inflammatory' and 'immune' macrophages killing listeria monocytogenes in murine infection. | two populations of efficiently phagocytic and bacteriolytic cells have been defined in the peritoneal cavity following infection of mice with listeria monocytogenes. one was the result of a transient inflammatory response 2 days after intraperitoneal (i.p.) infection. it consisted of a mixture of monocyte/macrophages and neurotrophils which, when separated on percoll gradients or by adherence, were both highly bacteriolytic compared with normal resident peritoneal macrophages. it was rich in rec ... | 1990 | 1964672 |
| attenuated mutants of the intracellular bacterium listeria monocytogenes obtained by single amino acid substitutions in listeriolysin o. | listeriolysin o (llo), a major virulence factor of the intracellular bacterium listeria monocytogenes, shares with other known 'thiol-activated toxins' a conserved undecapeptide, ectglawewwr, located in the c-terminal region of the protein and containing the unique cysteine of the molecule. single amino acid substitutions were created in this region to study the role of cysteine and tryptophan residues in the lytic activity of llo as well as in the virulence of the bacterium. transformation of a ... | 1990 | 1965218 |
| detection of anti-listeriolysin o for serodiagnosis of human listeriosis. | to see whether detection of antibodies against listeriolysin o (llo) could be used to diagnose human listeriosis, sera from 28 patients infected with listeria monocytogenes and 101 controls were tested by dot-blot titration with purified llo. 27 patients (96.4%) with listeriosis produced specific anti-llo. anti-llo was detected in 8 (15.6%) of 51 healthy controls and in 6 (12.0%) of 50 controls who had various bacterial, fungal, and viral infections. anti-llo titres did not exceed 100 in these t ... | 1990 | 1969016 |
| survival and growth of listeria monocytogenes on irradiated poultry carcasses. | 1990 | 1970086 | |
| transferable plasmid-mediated antibiotic resistance in listeria monocytogenes. | a strain of listeria monocytogenes, isolated from a patient with meningoencephalitis, was resistant to chloramphenicol, erythromycin, streptomycin, and tetracycline. the genes conferring resistance to these antibiotics were carried by a 37-kb plasmid, pip811, that was self-transferable to other l monocytogenes cells, to enterococci-streptococci, and to staphylococcus aureus. the efficacy of transfer and the stability of pip811 were higher in enterococci-streptococci than in the other gram-positi ... | 1990 | 1972210 |
| antibiotic resistance of listeria monocytogenes. | 1990 | 1975026 | |
| multiresistant strain of listeria monocytogenes in septic abortion. | 1990 | 1975353 | |
| listeria, plasmids, antibiotic resistance, and food. | 1990 | 1976982 | |
| foodborne listeriosis. | 1990 | 1978036 | |
| restriction endonuclease analysis of chromosomal dna from listeria monocytogenes strains. | restriction endonuclease analysis of chromosomal dna was applied to thirteen listeria monocytogenes strains alongside the more conventional typing methods of serotyping and phage typing. the organisms were isolated from cases of sporadic listeriosis (nine strains); from an occasional nosocomial cluster (two strains); and from food samples (two strains). purified dnas were digested with ecori restriction endonuclease, and restriction fragments separated by electrophoresis. restriction patterns co ... | 1990 | 1979278 |
| characterization of listeria monocytogenes isolates by southern blot hybridization. | a synthetic deoxyribonucleotide probe for virulent listeria monocytogenes, designated ado7, was evaluated for its ability to identify restriction fragments of l. monocytogenes with nucleic acid sequences homologous with the beta-hemolysin gene by southern blot hybridization of clinical and food isolates. the synthetic probe hybridized with three restriction fragments (approximately 1.1, 0.86, and 0.76 kb) of the serotype 1/2a isolates. southern blot hybridization of the serogroup 4b isolates ind ... | 1990 | 1979702 |
| chemotaxis in listeria monocytogenes. | listeria monocytogenes is a flagellated bacterium with a characteristic tumbling motion. it is intriguing to speculate that directional motility might facilitate penetration of the intestinal epithelium or selective colonization of the central nervous system or gravid uterus. there are conflicting reports on the extent of flagellation and degree of motility at temperatures corresponding to the internal environment of the mammalian host. no studies of chemotaxis in listeria have been reported. we ... | 1990 | 1979898 |
| [five cases of listeriosis in the elderly]. | we reported five cases of listeriosis (sepsis and meningitis) in the elderly in our hospital during the last 4 years, where no cases of listeriosis had been found. these 5 cases had diabetes mellitus, lung cancer, chronic respiratory failure, gastric ulcer and aplastic anemia respectively as their underlying diseases. at the onset of listeriosis, 3 cases received corticosteroid and 3 cases received h2-blocker. 2 patients were cured and 3 patients died. three autopsy cases had meningitis or menin ... | 1990 | 1981072 |
| [abscessing rhombencephalitis caused by listeria in an iummunodepressed patient]. | the cerebral trunk infection by listeria monocytogenes is a very rare process, with only 24 described cases and only 2 in immunodepressed patients. we present a new case of cerebral trunk encephalitis caused by listeria in a patient diagnosed of polyarteritis nodosa on steroids and cyclophosamide treatment and fatal evolution, and whose hemoculture, spinal fluid culture and cranial ct scan did not contribute to the diagnosis. a necrotizing lesion in the protuberance with mesencephalic extension ... | 1990 | 1982570 |
| listeria monocytogenes peritonitis associated with capd. | listeria monocytogenes peritonitis developed in a 67-year-old man on continuous ambulatory peritoneal dialysis following a catered luncheon. alcoholic liver disease was a predisposing factor. l. monocytogenes multiplies at 4 degrees c. it is often present in imported soft cheese, less often in chicken and other refrigerated food. listeria peritonitis has not been previously reported in australia. | 1991 | 1984589 |
| successful antepartum treatment of listeriosis. | a pregnant patient had a flulike illness at 27 weeks. listeria monocytogenes infection was diagnosed by blood cultures. electronic monitoring suggested the fetus was stressed. use of tocolytics inhibited uterine contractions while the mother was treated with intravenous ampicillin. four days later when labor began because of chorioamnionitis, the infant was delivered in good condition. | 1991 | 1986626 |
| tumor necrosis factor-independent il-6 production during murine listeriosis. | we report that tnf, il-6, and ifn-alpha/beta are produced by mice during either sublethal or lethal listeria monocytogenes infections. the quantities of these cytokines in infected spleens increase and decrease in concordance with bacterial numbers in these organs. while all of these cytokines were present in listeria-infected spleens, only il-6 and ifn-alpha/beta were found in the peripheral circulation. inasmuch as tnf has been reported to be responsible for the production of il-6 in vivo foll ... | 1991 | 1987284 |
| maternal listeriosis in pregnancy without fetal or neonatal infection. | maternal infection with listeria monocytogenes without fetal or neonatal involvement is relatively rare. eleven cases arising in england and wales between 1967 and 1988 are presented. | 1991 | 2002232 |
| listeria brainstem encephalitis: two own cases and literature review. | we analysed two of our own and 21 patients described in the literature with listeria brainstem encephalitis. the disease was characterised by a prodromal state with fever, nausea and headache followed by severe brainstem dysfunction with multiple cranial nerve palsies, ataxia, respiratory insufficiency and coma. the diagnosis was established by isolation of listeria monocytogenes from csf and/or serum. serological tests are without diagnostic evidence. cerebrospinal fluid examination may not ini ... | 1991 | 2013506 |
| immunosuppression induced by attenuated salmonella. evidence for mediation by macrophage precursors. | an attenuated aro a- strain of salmonella typhimurium, sl3235, was previously shown to afford excellent protection in c3heb/fej mice against challenge by virulent salmonella and cross-protection against listeria monocytogenes. in the present study, the immunologic status of immunized mice was evaluated by studying their ability to mount in vivo and in vitro plaque-forming cell responses to srbc. sl3235-immunized mice exhibited marked suppression in their ability to generate anti-srbc plaque-form ... | 1991 | 2016525 |
| listeriosis in patients infected with human immunodeficiency virus. | although resistance to listeria monocytogenes infection requires intact t cell-mediated immunity, only 20 patients with human immunodeficiency virus (hiv) infection and listeriosis (including one patient described herein) have been reported to date. listeriosis developed before aids in five cases. syndromes included meningitis in nine cases, bacteremia in nine, brain abscess in one, and endocarditis in one. eighteen patients were treated with ampicillin, penicillin, or amoxicillin with or withou ... | 1991 | 2017609 |
| antibiosis of leuconostoc gelidum isolated from meat. | a heterofermentative lactic acid bacterium isolated from meat packaged under elevated co2 levels was identified as leuconostoc gelidum, based on the description of this new species by shaw & harding (1989). it grows well at refrigeration temperatures but not at 35 degrees c. the organism produces an inhibitory substance that is inactivated by protease and trypsin, but not by catalase or by heating at 62 degrees c, for 30 min. the bacteriocin-like inhibitory substance is produced early in the gro ... | 1991 | 2019548 |
| [the administration of tobramycin in the 2nd and 3rd trimester of pregnancy: contribution to a pharmacokinetic study for the adaptation of posology]. | aminoglycosides are currently used during pregnancy for the treatment of staphylococcus, enterobacteriaceae, listeria monocytogenes, and pseudomonas aeruginosa infections. the pharmacokinetics of tobramycin, an aminoglycoside antibiotic, was investigated after a 2.5 mg/kg short intravenous infusion and a once-daily dose regime in 18 pregnant women divided into 2 groups of 9 during the second (group i: from 20 to 28 weeks of amenorrhoea) and the third (group ii: greater than or equal to 28 weeks ... | 1991 | 2019711 |
| application of purified polysaccharides from cell cultures of the plant echinacea purpurea to mice mediates protection against systemic infections with listeria monocytogenes and candida albicans. | purified polysaccharides from cell cultures of the plant echinacea purpurea were investigated for their ability to enhance phagocytes' activities regarding nonspecific immunity in vitro and in vivo. macrophages (m phi) from different organ origin could be activated to produce il-1, tnf alpha and il-6, to produce elevated amounts of reactive oxygen intermediates and to inhibit growth of candida albicans in vitro. furthermore, in vivo the substances could induce increased proliferation of phagocyt ... | 1991 | 2026472 |
| listeria monocytogenes endophthalmitis. | listeria endophthalmitis developed in an otherwise healthy woman. early identification of the microorganism after anterior chamber paracentesis and aggressive treatment with specific antibiotics through the intravitreal route resulted in complete recovery of visual acuity. | 1991 | 2028755 |
| listeria meningitis and paté. | listeria meningitis occurred in a 63 year old man who was in complete haematological remission following chemotherapy for acute myeloid leukaemia. the patient had followed department of health advice to immunocompromised patients and had avoided soft cheeses, cook-chill meals, and salads. he had, however, recently eaten paté produced in belgium. this was no longer available for examination but a coincidental survey of paté in the cardiff area found listeria monocytogenes in 16 out of 73 samples. ... | 1991 | 2030156 |
| effect of ammonium metavanadate on the mouse peritoneal macrophage lysosomal enzymes. | female b6c3f1 mice were injected intraperitoneally with ammonium metavanadate (2.5 or 10 mg v/kg), ammonium chloride, or sodium phosphate buffer (0.1 m, ph 7.2) every 3 d for 6 wk. resident peritoneal macrophage (pem) cytolysates were prepared and assayed for intracellular enzyme activities of beta-glucuronidase, n-acetyl-beta-d-glucosaminidase, acid phosphatase, and lysozyme, to investigate possible reasons for the depressive effect of ammonium metavanadate on the intracellular killing of liste ... | 1991 | 2033645 |
| infantile meningitis in england and wales: a two year study. | a two year prospective study identified 1922 cases of meningitis in children under 1 year of age. a further 201 cases were identified from other sources. the annual incidence of meningitis during the first year of life was 1.6/1000; during the first 28 days of life it was 0.32/1000, and among postneonatal infants it was 1.22/1000. the male:female ratio was 1.4:1. the overall case fatality rate was 19.8% for neonates and 5.4% for postneonatal infants. two thirds of deaths identified in the study, ... | 1991 | 2039250 |
| outbreak of neonatal listeriosis associated with mineral oil. | in june, 1989, an outbreak of nosocomial listeriosis occurred in costa rica. listeria monocytogenes was isolated from 9 ill infants 4 to 8 days old who were born after the delivery of an infant with early onset listeriosis. one nosocomial infection was fatal, 2 required mechanical ventilation and 1 resulted in hemiparesis. a higher proportion of cases than other infants born during the outbreak were delivered by cesarean section (55% vs. 24%, p = 0.04). compared with the mothers of 36 random con ... | 1991 | 2041663 |
| [acute bacterial and fungal neonatal meningitis]. | neonatal meningitis has two closely related features: the mechanism of infection and the nature of the pathogen. when transmitted from mother to foetus, the infection is mainly caused by one of three microorganisms: streptococcus group b, escherichia coli or listeria monocytogenes. it may occur before birth, in which case meningitis is of early onset and has a rather poor prognosis. when it occurs later, the infection is a pathological consequence of physiological bacterial colonization, and its ... | 1991 | 2063133 |
| [neuromeningeal listeria infections in adults. clinical, biological and therapeutic aspects. apropos of 36 cases]. | in this retrospective study, 36 cases of listeria monocytogenes meningitis were reviewed. a bacteriological confirmation was obtained for every patient either by lombar puncture or blood culture. the clinical picture and the composition of the cerebrospinal fluid were polymorphous. most patients were previously in good health, while 10 of them (28%) had a predisposing factor: pregnancy, gastrectomy, diabetes mellitus, alcoholism or immunosuppression. the outcome was favorable in 23 patients (64% ... | 1991 | 2064172 |
| liposome-entrapped ampicillin in the treatment of experimental murine listeriosis and salmonellosis. | the tissue distribution of ampicillin entrapped in liposomes was studied in normal noninfected mice and showed that ampicillin concentrated mostly in the liver and spleen. liposomate ampicillin was significantly more effective than free ampicillin in reducing splenic and hepatic bacterial counts in c57bl/ka nude mice chronically infected with listeria monocytogenes egd. it was also significantly more effective than free ampicillin in reducing mortality in c57bl/6 mice acutely infected with salmo ... | 1991 | 2069386 |
| maternal-fetal listeriosis: 2 case reports. | two cases of maternal-fetal infection with listeria monocytogenes are reported. both women were admitted with influenza-like symptoms and preterm labor at 32 and 34 weeks of gestation, respectively. the infants were delivered within a few days of onset of maternal symptoms. one infant was seriously ill with meningitis and subsequently developed hydrocephalus. the other infant suffered from septicemia, but had no sequelae. it is recommended always to consider the diagnosis listeriosis in pregnant ... | 1991 | 2071059 |
| factors involved in the depression of hepatic mixed function oxidase during infections with listeria monocytogenes. | a number of infections are capable of depressing the capacity of the liver to metabolize drugs. we have studied a number of factors which could be involved in the depression of cytochrome p-450 and related drug biotransformation enzymes during infections with listeria monocytogenes. during the course of the infection, drug metabolism and heme content of hepatic microsomes were depressed but heme oxygenase was elevated. a free radical scavenger alpha-tocopherol did not prevent the loss and xanthi ... | 1991 | 2071296 |
| hepatocidal toxicity of listeria species. | a novel rat hepatocidal test, based on morphological changes in monolayer culture and the percentage of lactate dehydrogenase (ldh) released into the medium after exposure to culture filtrates of listeria spp. was used to determine listerial toxicity and pathogenicity. primary cultures of rat hepatocytes exposed to brain heart infusion (bhi) culture filtrates from atcc strains of listeria monocytogenes and l. ivanovii, released 91-92% and 95% of ldh after 3 h and 18.5 h, respectively. cultured m ... | 1990 | 2083836 |
| antimicrobial activity and beta-lactamase stability of bmy-28232, parent compound of an oral cephalosporin. | bmy-28232, an aminothiazolyl imino methoxy cephalosporin which is available as an orally absorbed acetoxyethyl ester, inhibited strains of methicillin-susceptible staphylococcus aureus, hemolytic streptococci, streptococcus pneumoniae, escherichia coli, klebsiella species, and many strains of proteus and providencia stuartii at concentrations less than 1 microgram/ml, including isolates resistant to cephalexin and cefaclor. it had activity similar to that of cefixime, but was more active against ... | 1990 | 2086221 |
| induction of colony-stimulating factor(s) after administration of a traditional chinese medicine, xiao-chai-hu-tang (japanese name: shosaiko-to). | colony stimulating factor (csf)-rich serum was obtained from mice injected intraperitoneally (ip) with shosaiko-to, a traditional chinese herbal medicine. transfer of the csf-rich serum into naive mice augmented the resistance against listeria monocytogenes. a dose-dependent induction of csf was observed in mice given shosaiko-to via intravenous route as well as via intraperitoneal route. since the serum csf induction was observed in both lipopolysaccharide (lps)-responder c3h/he mice and lps-no ... | 1990 | 2092044 |
| a homogeneous population of lymphokine-activated killer (lak) cells is incapable of killing virus-, bacteria-, or parasite-infected macrophages. | previous reports have suggested a role for natural killer (nk) cells in directly lysing host cells infected with bacteria and other intracellular microorganisms. here, we determined the inability of a highly homogeneous population of lymphokine activated killer (lak) cells to kill macrophages infected with the following intracellular parasites: mycobacterium avium, listeria monocytogenes, legionella pneumophila, toxoplasma gondii, and trypanosoma cruzi. in parallel cytotoxicity assays, lak cells ... | 1990 | 2104576 |
| bacterial lipopolysaccharide potentiates gamma interferon-induced cytotoxicity for normal mouse and rat fibroblasts. | gamma interferon (ifn-gamma) can be cytolytic for normal mouse fibroblasts isolated from embryonic or adult tissue (r. dijkmas, b. decock, h. heremans, j. van damme, and a. billiau, lymphokine res. 8:25-34, 1989). this cytotoxicity has been shown to be transcription and translation dependent, thereby suggesting involvement of a suicidelike mechanism. the dose of ifn-gamma required for cytotoxicity is higher than that needed for antiviral and macrophage activation but can be reduced 10- to 100-fo ... | 1990 | 2104601 |
| listeria continues to cause problems. | 1990 | 2104824 | |
| alveolar macrophage function in rats with severe protein calorie malnutrition. arachidonic acid metabolism, cytokine release, and antimicrobial activity. | to investigate the effects of protein calorie malnutrition (pcm) on alveolar macrophage function, we measured antimicrobial activity, il-1 and tnf production, and arachidonic acid metabolism in alveolar macrophages of infant rats with moderate and severe pcm. groups of weanling male rats were fed a diet containing 0.8% protein (pcm) or 24% protein (control). a third group (pair fed) was fed limited amounts of the control diet that matched the mean daily dietary intake of the pcm group. after 4 w ... | 1990 | 2104909 |
| listeriosis in patients with hiv infection: clinical manifestations and response to therapy. | although listeriosis is an uncommon infection in patients with human immunodeficiency virus (hiv) infection, the frequency of listeriosis in new york city has increased because of the increase in the number of hiv-infected patients. the medical records of 30 patients admitted to three medical centers in new york city from 1981 to 1988 with infections due to listeria monocytogenes were reviewed. six patients had aids, one was seropositive and asymptomatic, and four had risk factors for hiv infect ... | 1990 | 2104931 |
| characterization of a cell population which amplifies the anticryptococcal delayed-type hypersensitivity response. | cell-mediated immunity to cryptococcus neoformans can be detected by delayed-type hypersensitivity (dth) to a culture filtrate antigen of c. neoformans. recently, we have identified a population of cells in spleens of mice immunized with cryptococcal antigen that, when transferred to recipient mice at the time of immunization, amplifies the anticryptococcal dth response. if the cell donor mice are treated with cyclosporin a during induction of the anticryptococcal dth response, the amplifier cel ... | 1990 | 2105273 |
| listeria meningitis in infants and children. | 1990 | 2105480 | |
| preclinical screening and analysis of the immunotoxic and immunomodulatory activity using a multiple immunoassay (mia) in mice. | screening and analysis of immunotoxic and immunomodulatory activity has become an integral component in preclinical studies of pharmaceuticals and xenobiotics. in an attempt to replace laborious and expensive batteries of assays used at present we developed a multiple immunoassay (mia) enabling the determination, in a single mouse, of: the weight of the thymus, spleen and a group of lymph nodes; delayed type hypersensitivity and antibody response to srbc; phagocytic activity of peritoneal macrop ... | 1990 | 2105913 |
| a pyrolysis-mass spectrometry study of corynebacterium spp. | clinical (66) and collection (38) strains of corynebacterium spp., including c. jeikeium and cdc group d2, and of listeria monocytogenes were examined. conventional characters used in species identification were assessed by a microbiochemical method, and pyrolysis-mass spectrometry (py-ms) was performed with a horizon instruments pyms 200x. classification based on py-ms data yielded clusters that corresponded with species identification and classification groups from conventional data. one small ... | 1990 | 2106034 |
| listeria in food. | 1990 | 2106106 | |
| effects of growth temperature and strictly anaerobic recovery on the survival of listeria monocytogenes during pasteurization. | listeria monocytogenes f5069 was suspended in either trypticase soy broth-0.6% yeast extract (tsbye) or sterile, whole milk and heated at 62.8 degrees c in sealed thermal death time tubes. severely heat-injured cells were recovered in tsbye within sealed thermal death time tubes because of the formation of reduced conditions in the depths of the tsbye. also, the use of strictly anaerobic hungate techniques significantly increased recovery in tsbye containing 1.5% agar compared with aerobically i ... | 1990 | 2106284 |
| efficacy of a variety of disinfectants against listeria spp. | the efficacy of 14 disinfectants against listeria innocua and two strains of listeria monocytogenes in the presence of organic matter was studied. quantitative efficacy tests were used. many of the disinfectants tested were not as effective on listeria spp. when the test organisms were dried onto the surface of steel disks (carrier tests) as they were when the organisms were placed in suspension (suspension test). the presence of whole serum and milk (2% fat) further reduced the disinfectant cap ... | 1990 | 2106285 |
| immune responses in balb/c mice following immunization with aromatic compound or purine-dependent salmonella typhimurium strains. | two near isogenic strains of salmonella typhimurium hwsh, stably mutated in either the aroa gene affecting the biosynthesis of aromatic compounds, or the pura gene affecting the biosynthesis of purines, were administered intravenously as live attenuated vaccines to balb/c mice. hwsh aroa-immunized mice were well protected against intravenous (i.v.) challenge with wild-type virulent hwsh for at least 10 weeks, whereas hwsh pura-immunized mice were unprotected. furthermore, hwsh aroa-immunized mic ... | 1990 | 2106482 |
| expression of systemic protection and delayed-type hypersensitivity to listeria monocytogenes is mediated by different t-cell subsets. | the relationship between acquired cellular resistance and delayed-type hypersensitivity (dth) during the immune response to listeria monocytogenes was investigated. treatment of concanavalin a-stimulated listeria-immune spleen cells with anti-cd8 antibody plus complement abrogated the adoptive transfer of systemic antilisterial immunity but had no effect on the transfer of dth. in contrast, in vitro depletion of the cd4+ t-cell subset eliminated the ability of culture-activated cells to transfer ... | 1990 | 2106491 |
| selective plating medium for quantitative recovery of food-borne listeria monocytogenes. | a new plating medium (lithium chloride-ceftazidime agar [lca]) was designed to quantitatively recover food-borne listeria monocytogenes in the form of large colonies while inhibiting most other food-borne microorganisms. this medium included brain heart infusion agar as the nutritive agar base and a combination of selective agents (licl, glycine anhydride, and ceftazidime). comparison of lca and lithium chloride-phenylethanol-moxalactam agar (lpm) indicated that both were equally effective for t ... | 1990 | 2106825 |
| serum antibody response to listeria monocytogenes, listerial excretion, and clinical characteristics in experimentally infected goats. | we induced an experimental listeriosis in five goats by oral inoculation of listeria monocytogenes serovar 1/2a. the resulting generalized bacteremia was reflected by systemic illness in four of the five animals inoculated and by excretion of l. monocytogenes in milk by all five animals. by using an enzyme immunoassay, we recorded a markedly enhanced immunoglobulin g (igg) antibody response in the two youngest and most seriously ill test animals. in these, the elimination of l. monocytogenes fro ... | 1990 | 2107204 |
| sequential appearance of gamma/delta- and alpha/beta-bearing t cells in the peritoneal cavity during an i.p. infection with listeria monocytogenes. | to search for a potential role of t cell antigen receptor (tcr) gamma/delta-bearing cells in host-defense against listeria monocytogenes, we analyzed the sequential appearance of gamma/delta and alpha/beta t cell in the peritoneal exudate cells (pec) during an i.p. infection with sublethal dose (2 x 10(3) of viable listeria organisms in mice. the pec on day 1 after the infection consisted of 48% macrophages and 50% lymphocytes, most of which were surface igm+ (b) cells. the number of pec increas ... | 1990 | 2108043 |
| lymphokines and bacteria, that induce tumoricidal activity, trigger a different secretory response in macrophages. | the abilities of various macrophage-activating agents to trigger tumoricidal activity and/or the secretion of prostaglandin e2 (pge2), interleukin 6 (il 6) and transforming growth factor beta (tgf beta) in bone marrow-derived mononuclear phagocytes (bmm phi) in vitro were comparatively assessed. induction of tumoricidal activity by lymphokines, that is only short-lived, was not associated with enhanced secretion of these activities by bmm phi; in contrast, incubation with heat-killed facultative ... | 1990 | 2108046 |
| intracellular and cell-to-cell spread of listeria monocytogenes involves interaction with f-actin in the enterocytelike cell line caco-2. | listeria monocytogenes penetrates and multiplies within professional phagocytes and other cells such as the caco-2 human enterocytelike cell line. listeriolysin o, a membrane-damaging cytotoxin accounts for intracellular multiplication through lysis of the membrane-bound phagocytic vacuole. this work demonstrates that once released within the cytosol, l. monocytogenes acquires the capacity to spread intracellularly and infect adjacent cells by interacting with host cell microfilaments. such evid ... | 1990 | 2108086 |
| augmentation of gg2ee macrophage cell line-mediated anti-candida activity by gamma interferon, tumor necrosis factor, and interleukin-1. | the expression of anti-candida activity in the gg2ee macrophage cell line, generated by immortalization of fresh bone marrow with v-raf and v-myc oncogenes, was studied. gg2ee cells spontaneously inhibited the growth of an agerminative mutant of candida albicans in vitro. the anti-candida activity was maximal after 8 h of coculture and was proportional to the effector-to-target ratio. gamma interferon (ifn-gamma), interleukin-1 (il-1), and tumor necrosis factor (tnf) all significantly enhanced t ... | 1990 | 2108087 |
| growth of listeria monocytogenes at refrigeration temperatures. | the growth of three strains of listeria monocytogenes at refrigeration temperatures (-0.5 to 9.3 degrees c) in chicken broth and/or uht milk was determined using a rocking temperature gradient incubator. minimum growth temperatures ranged from -0.1 to -0.4 degree c for the three strains. lag times of 1-3 d and 3 to greater than 34 d were observed with incubation at 5 and 0 degrees c respectively. corresponding generation times ranged from 13-24 h at 5 degrees c and 62-131 h at 0 degree c. the ty ... | 1990 | 2108109 |
| treatment of experimental listeriosis by ci 934, a new quinolone. | ci 934, a new quinolone, is only marginally more active in vitro against listeria monocytogenes and other listeria spp. than ciprofloxacin. a bactericidal effect is seen only after several hours of incubation. however, mice infected with a virulent strain of l. monocytogenes were protected by parenteral treatment with ci 934. with a dosage of 2 x 2 mg ci 934 per day for three days almost complete remission could be achieved. these results are somewhat better than those obtained in previous exper ... | 1990 | 2108112 |
| measurement of macrophage adherence and spreading with weak electric fields. | a new method to monitor macrophage attachment on protein-coated surfaces and spreading in response to activating agents is described. murine macrophages were cultured on small gold electrodes coated with protein, and attachment and spreading were detected as electrical impedance changes. the rate of attachment of cells to fibronectin-coated electrodes was measured to be significantly greater than to other proteins tested. activation agents used included interferon-gamma, lipopolysaccharide and h ... | 1990 | 2108221 |
| human listeriosis in britain, 1967-85, a summary of 722 cases. 1. listeriosis during pregnancy and in the newborn. | clinical information was collected on 722 cases of listeria monocytogenes infections in humans occurring in britain between 1967 and 1985: 248 cases (34%) were associated with pregnancy (maternal, foetal, and neonatal), and comprised 9 cases (4%) of maternal bacteraemia without infection of the foetus; 42 cases (19%) of intra-uterine deaths; 118 cases (54%) of neonatal infection diagnosed within 2 days post-partum; and 50 cases (23%) of neonatal infection diagnosed as ill after 2 days post-partu ... | 1990 | 2108869 |
| human listeriosis in britain, 1967-85, a summary of 722 cases. 2. listeriosis in non-pregnant individuals, a changing pattern of infection and seasonal incidence. | clinical information was collected on 722 cases of listeria monocytogenes infections in humans occurring in britain between 1967 and 1985. this series comprised 34% (248 cases) associated with pregnancy and 66% (474 cases) in non-pregnant adults and juveniles. the cases not associated with pregnancy comprised: 76% in patients with severe underlying illness (of which 34% had central nervous system infections, and 42% bacteraemia without involvement of the central nervous system); 21% in previousl ... | 1990 | 2108870 |
| difference in the induction of macrophage interleukin-1 production between viable and killed cells of listeria monocytogenes. | t-cell-mediated immunity to listeria monocytogenes in mice, as determined by delayed-type hypersensitivity and acquired resistance, was induced by immunization with viable bacteria but not with killed bacteria, even when killed cells were injected in a high dose or repeatedly. t cells obtained from mice immunized with viable l. monocytogenes were readily stimulated with killed-bacterial antigens, resulting in t-cell proliferation in vitro and expression of a delayed footpad reaction in vivo. aft ... | 1990 | 2108928 |
| roles of cd4+ and cd8+ cells, and the effect of administration of recombinant murine interferon gamma in listerial infection. | studies were made on the effects of in vivo administration of anti-cd4 mab, anti-cd8 mab, or a combination of both mabs on multiplication of bacteria, the levels of serum transaminases, and mortality in mice infected with listeria monocytogenes. results showed that in sublethal infection, cd8+ cells enhanced the peak of bacterial multiplication and liver cell necrosis, and cd4+ cells suppressed cd8+ cell-mediated enhancement. results also showed that either cd4+ or cd8+ cells were necessary for, ... | 1990 | 2109036 |
| recurrent listeria monocytogenes bacteraemia in a liver transplant patient. | we report a case of a recurrent listeria monocytogenes bacteraemia in a 46 year-old liver transplant patient. serotyping revealed that the two episodes of bacteraemia were caused by different strains. the possibility of a recrudescence of a persisting infection was rejected. we concluded that the recurrent bacteraemia in this predisposed patient was due to re-infection, and that antibiotic treatment (amoxicillin plus an aminoglycoside) resulted in a complete eradication of the infective microorg ... | 1990 | 2110115 |
| listeria isolations from feces of patients with diarrhea and from healthy food handlers. | a study was undertaken on the presence and frequency of listeria sp. in feces from 1,000 patients suffering from diarrheal diseases and from 2,000 healthy persons. furthermore, the feces of patients were examined for other well-documented enteropathogens such as campylobacter, salmonella, shigella, staphylococcus aureus, yersinia enterocolitica, protozoa and rotavirus as well as for organisms of questionable enteropathogenic potency such as fungi, i.e. candida. finally, in continuation of previo ... | 1990 | 2110118 |
| bacillus subtilis expressing a haemolysin gene from listeria monocytogenes can grow in mammalian cells. | intracellular parasites can be classified into those that reside within a host vacuole and those which grow directly in the host cytoplasm. members of the latter group, which includes rickettsia, shigellae, trypanosoma cruzi, and listeria monocytogenes, possess haemolytic activity associated with the ability to enter the host cytoplasm. therefore mutants of l. monocytogenes lacking a pore-forming haemolysin, listeriolysin o, do not escape from the endosomal compartment and consequently fail to b ... | 1990 | 2110628 |
| in vitro bactericidal activity of amoxicillin, gentamicin, rifampicin, ciprofloxacin and trimethoprim-sulfamethoxazole alone or in combination against listeria monocytogenes. | the in vitro bactericidal activity of amoxicillin, gentamicin, rifampicin, ciprofloxacin and trimethoprim-sulfamethoxazole alone or in combination was determined against seven strains of listeria monocytogenes by the killing curve method. amoxicillin plus gentamicin was the most rapidly bactericidal combination, whereas trimethoprim-sulfamethoxazole was less bactericidal at 6 h but as bactericidal at 24 h. the combination of trimethoprim-sulfamethoxazole with either amoxicillin, ciprofloxacin or ... | 1990 | 2110900 |
| distribution of serovars of listeria monocytogenes isolated from different categories of patients with listeriosis. | an analysis was made of the distribution of serovars of listeria monocytogenes isolated from 1363 patients with listeriosis. overall, serovar 4b was found in 64% of cases, serovar 1/2a in 15%, serovar 1/2b in 10%, and serovar 1/2c in 4%. the patients were categorised as pregnancy associated cases, non-pregnant previously healthy cases, and non-pregnant cases with severe underlying illness. the serovars were unequally distributed between these three groups of patients. serovar 1/2b occurred most ... | 1990 | 2110901 |
| same-day identification scheme for colonies of listeria monocytogenes. | a diagnostic scheme is described for the same-day identification of food-borne cells of listeria monocytogenes that emerge in 40 h at 30 degrees c as large colonies, representatives of which are used to advantage as heavy inocula on agar plates for the rapid determination of hemolytic activity and acidification of rhamnose and xylose. additional tests consisting of phase-contrast microscopy for cell morphology and motility, the catalase production test, and the koh viscosity test in place of gra ... | 1990 | 2111113 |
| microbiological quality and safety of zoo food. | two types of commercial products for feeding zoo animals (a frozen meat product, referred to as zoo food, and a dry product, referred to as dry food) were microbiologically examined for spoilage organisms (aerobic, psychrotrophic, coliform, escherichia coli, mold, and yeasts) and pathogens (salmonella spp., listeria monocytogenes, and campylobacter jejuni). levels of microorganisms in frozen ground zoo food were compared with those in frozen ground beef and frozen ground turkey meat. the level o ... | 1990 | 2111115 |
| pathogenicity of listeria monocytogenes grown on crabmeat. | the pathogenicity of listeria monocytogenes as influenced by growth on crabmeat at 5 and 10 degrees c was studied. crabmeat was inoculated with l. monocytogenes v7 (ca. 10(4) cfu/g) and incubated for up to 14 days at 5 and 10 degrees c. at selected incubation times, l. monocytogenes was removed from crabmeat by washing with 0.1 m potassium phosphate buffer (ph 7.0), and populations were determined by surface plating on licl-phenylethanol-moxalactam agar. buffered suspensions were then centrifuge ... | 1990 | 2111120 |
| surface listeria monocytogenes carbohydrate-binding components revealed by agglutination with neoglycoproteins. | carbohydrate-binding components were shown to be present at the surface of listeria monocytogenes by means of a panel of neoglycoproteins using direct agglutination. these lectin-like components bind on neoglycoproteins bearing d-glucosamine, l-fucosylamine, or para-amino-phenyl-alpha-d-mannopyrannoside residues. the interactions were inhibited by the carbohydrate moieties specific to the neoglycoproteins. the protein nature of the lectin-like components of l. monocytogenes was ascertained by th ... | 1990 | 2111260 |
| the gene coding for protein p60 of listeria monocytogenes and its use as a specific probe for listeria monocytogenes. | the gene of listeria monocytogenes that encodes a major extracellular protein (p60) was cloned in escherichia coli. the gene was designated iap, as p60 was previously shown to represent an invasion-associated protein (m. kuhn and w. goebel, infect. immun. 57:55-61, 1989). the recombinant e. coli clone expressed p60, as shown by immunoblotting. the complete nucleotide sequence of iap was determined. the deduced amino acid sequence of p60 (484 amino acids) contains a putative n-terminal signal seq ... | 1990 | 2111287 |
| activation of mouse peritoneal macrophages during infection with salmonella typhimurium does not result in enhanced intracellular killing. | our study was performed to investigate whether macrophages become activated during an infection with salmonella typhimurium and, if so, whether these activated macrophages kill s. typhimurium faster than resident macrophages. mice received i.v. injections with a sublethal number of s. typhimurium; on about day 12 of the infection the numbers of bacteria in the liver and the spleen were maximal. during the infection, activation of peritoneal macrophages could be demonstrated on the basis of three ... | 1990 | 2111344 |
| human listeriosis in scotland 1967-1988. | in order to study the epidemiology of listeriosis from 1967-1988 in scotland, various sources of data were examined. these included reports by laboratories, reference laboratory records, hospital death and discharge records, death certificates and hospital laboratory records. cases were reported from 13 of scotland's 15 health boards. case ascertainment via laboratory reports to the communicable diseases (scotland) unit was validated in two health boards. a total of 198 cases was identified with ... | 1990 | 2111351 |
| penicillin-binding protein 3 of listeria monocytogenes as the primary lethal target for beta-lactams. | penicillin-binding proteins (pbps) of listeria monocytogenes were detected by their ability to bind to [2,3-3h]benzylpenicillin. five proteins with mrs of 95,000, 84,000, 80,000, 76,000, and 49,000 were detected. pbps 1 to 4 had a high affinity for [2,3-3h]benzylpenicillin and were relatively scarce (80 to 150 molecules per cell). in contrast, pbp 5 was more abundant (600 molecules per cell) but had a low affinity for [2,3-3h]benzylpenicillin. l. monocytogenes has a relatively high natural resis ... | 1990 | 2111657 |
| listeria monocytogenes--threat to a safe food supply: a review. | listeria monocytogenes can cause circling disease, encephalitis, meningitis, septicemia, and mastitis in dairy cattle. shedding of the pathogen from the udder or contamination from the environment can lead to presence of l. monocytogenes in raw milk. surveys indicate the pathogen is in about 4% of us raw milks. although htst pasteurization commonly inactivates l. monocytogenes, evidence suggests that under unusual circumstances minimal survival is possible. the pathogen grows well in liquid dair ... | 1990 | 2111832 |
| listeria monocytogenes colonization of broiler chickens. | in three trials, a total of 108 broiler chickens were unchallenged or challenged orally with either 10(2) or 10(6) cells of listeria monocytogenes at 1, 14, or 35 days of age. the birds were kept in separate wire-floored brooders and growout batteries, fed unmedicated broiler-starter rations ad libitum, and killed 7 days postchallenge. the ceca, duodenum, spleen, liver (including gall bladder), and a cloacal swab were sampled from each bird and were analyzed for the presence of l. monocytogenes. ... | 1990 | 2111910 |
| in-vitro synergy testing of nine antimicrobial combinations against listeria monocytogenes. | in-vitro antimicrobial synergy against listeria monocytogenes was assessed using nine combinations in chequerboard (bacteriostatic) tests and time-kill (bactericidal) studies. ampicillin/gentamicin and trimethoprim/sulphamethoxazole were the most synergistic combinations in bacteristatic tests, whereas gentamicin with ampicillin, trimethoprim or vancomycin and trimethoprim/sulphamethoxazole were the most synergistic in bactericidal tests. gentamicin-containing combinations were most effective at ... | 1990 | 2112538 |
| role of tumor necrosis factor in listeria resistance of nude mice. | the effects of sheep anti-murine recombinant tumor necrosis factor-alpha (tnf-alpha) on resistance to listeria monocytogenes infection were studied in t cell-deficient nu/nu mice. the sheep anti-tnf-alpha antibody preparation was specific for tnf since it neutralized 300 u of recombinant murine tnf-alpha in vitro at a dilution of up to 1/1,000 but did not neutralize 32 u of interferon (ifn)-alpha, -beta or 32 u of ifn-gamma in vitro at a 1/20 dilution. when tested in vivo in sublethally listeria ... | 1990 | 2113160 |
| fish oil dietary supplementation reduces ia expression in rat and mouse peritoneal macrophages. | preliminary studies suggest that administration of fish oil fatty acids may be beneficial in several immunological diseases; therefore, we studied the effect of fish oil dietary supplementation on the expression of ia in stimulated murine peritoneal macrophages. rats (n = 19) and mice (n = 27) on standard rodent feeding were separated in experimental (e) and control (c) groups that received fish oil or saline solution, respectively, daily for 4 weeks by esophageal gavage. cholesterol serum level ... | 1990 | 2113444 |
| linking environmental and human strains of listeria monocytogenes with isoenzyme and ribosomal rna typing. | 1990 | 2113872 | |
| accessory function of kupffer cells in the antigen-specific blastogenic response of an l3t4+ t-lymphocyte clone to listeria monocytogenes. | the function of kupffer cells in the development of protective immunity to infection by listeria monocytogenes is controversial. to determine their role in antilisterial host defenses, kupffer cells were separated from other nonparenchymal cells of the liver by centrifugation on a metrizamide gradient followed by adherence to glass or plastic. the resultant highly enriched kupffer cell population supported the antigen-specific blastogenic response [( 3h]thymidine incorporation) of cloned l3t4+ t ... | 1990 | 2114361 |
| evidence that endogenous gamma interferon is produced early in listeria monocytogenes infection. | it has been presumed that gamma interferon (ifn-gamma), which plays an essential role in antilisterial resistance, is produced late in listeria monocytogenes infection. in the present study, however, ifn-gamma was detected in the bloodstreams and spleens of mice from days 1 to 4 of l. monocytogenes infection by both a double-sandwich enzyme-linked immunosorbent assay and an immunohistochemical technique, suggesting that endogenous ifn-gamma is produced early but not late in l. monocytogenes infe ... | 1990 | 2114368 |
| iron acquisition systems of listeria monocytogenes. | the uptake of iron by listeria monocytogenes was studied. the microorganism was found to bind both 59fe(ii) and [59fe3+]citrate. in contrast, l. monocytogenes was unable to acquire iron from [59fe3+]ferroxamine or [59fe3+]edta or as 59fecl3. the data suggest that iron is acquired principally as iron(ii) and that a citrate-inducible iron uptake system is also operative. | 1990 | 2115028 |
| listeriosis--problems and therapeutic options. | 1990 | 2115036 | |
| the role of macrophage activation and of bcg-encoded macrophage function(s) in the control of mycobacterium avium infection in mice. | following the intraperitoneal inoculation of 2.5 x 10(8) colony-forming units of mycobacterium avium strain atcc 25291, there was bacillary growth in the liver, spleen and peritoneal cavity of c57bl/6, c57bl/10, dba/1 and balb/c mice whereas dba/2, c3h/he, cba/ca and cd-1 mice controlled the infection showing constant or slightly decreasing numbers of viable bacteria in the liver and spleen and effective clearance of the bacilli from the peritoneal cavities. the acquisition of non-specific resis ... | 1990 | 2115416 |
| relationship between colony-stimulating activity and interferon production during infection. | normal mouse spleen, when cultured in vitro for 3 days in the presence of 10(8) heat-killed listeria monocytogenes organisms, produced colony-stimulating factors (csf) that were capable of supporting the production of haemopoietic colonies by bone marrow cells in semi-solid agar, or supporting bone marrow proliferation in liquid medium. in contrast, when the spleen cells were prepared from mice that had been infected with listeria monocytogenes, colony-stimulating activity (csa) was no longer de ... | 1990 | 2115498 |
| participation of pbp 3 in the acquisition of dicloxacillin resistance in listeria monocytogenes. | purified membranes of listeria monocytogenes atcc 15313 contain at least five penicillin-binding proteins. in two dicloxacillin-resistant mutants, derived from a sensitive parent strain, a 16-fold increase in the mic of dicloxacillin was observed. a less-significant increase was detected in the mics of other beta-lactam drugs. in the mutants, pbp 3 lost its strong affinity for dicloxacillin, but remained fully susceptible to binding of 125i-penicillin x, as compared with the wild-type strain. pb ... | 1990 | 2115510 |
| [listeria meningoencephalitis in a 2-year-old boy]. | we report the unusual case of a two year old boy with encephalomeningitis caused by listeria monocytogenes. the patient was hospitalized with the classical signs of severe bacterial meningitis. the microbiological investigations gave proof of listeria monocytogenes as causative agent 36 hours later. antibiotic treatment with ampicillin and gentamicin resulted in a prompt improvement of the boy's condition. the boy was discharged four weeks later. | 1990 | 2115616 |
| an outbreak of listerial myelitis in sheep. | 1990 | 2115768 | |
| antibiotic susceptibility of type b haemophilus influenzae and streptococcus pneumoniae, and antibiotic concentration in cerebrospinal fluid. | antibiotic susceptibilities of 38 type b haemophilus influenzae and 28 streptococcus pneumoniae strains isolated from cerebrospinal fluid, blood and other specimens between 1973 and 1988 were studied. minimal inhibitory concentrations (mics) of ampicillin against 10 beta-lactamase positive and 28 negative h. influenzae isolates were 32-64 and 0.25 micrograms/ml, respectively. the mic of chloramphenicol against one of the beta-lactamase positive h. influenzae strains was 8 but mics against the re ... | 1990 | 2116062 |
| overlay technique for direct detection and identification of haemolytic listeria on selective plating medium. comparison of five media. | an overlay technique is proposed for the identification and counting of haemolytic listeria colonies directly on selective plating media. the technique was applied to different listeria-selective plating media. in pure culture studies with collection strains, the overlay technique was more efficient and reliable for detection haemolytic listeria species compared with the incorporation of blood into the agar. the efficacy of the overlay technique for the direct detection of haemolytic colonies of ... | 1990 | 2116701 |
| contamination of raw milk by listeria monocytogenes on dairy farms. | possible sources of exogenous contamination of raw milk by listeria monocytogenes were examined on four dairy farms of different size and type of animal housing during morning milking. feeds, including hay and concentrates, were found to be major sources of both pathogenic and nonpathogenic species of listeria on the barns. l. innocua was the only species isolated from the grass silage, which was of good quality on all the farms. the numbers of listeria were below 10(2)/g in all feed samples. fe ... | 1990 | 2116711 |
| epidemiological studies on the occurrence of listeria monocytogenes in the feces of dairy cattle. | seasonal variation in the fecal shedding of listeria spp. in dairy cattle was examined by collecting a total of 3,878 fecal samples during a period of two years. the prevalences of listeria spp. and l. monocytogenes were higher during the indoor season (12.7% and 9.2%, respectively) than in samples collected from the animals on pasture (5.3% and 3.1%, respectively). the highest frequencies of listeria spp. (19.4%) and l. monocytogenes (16.1%) were detected in december. listeriae were isolated fr ... | 1990 | 2116712 |
| effect of prior heat shock on heat resistance of listeria monocytogenes in meat. | the effect of prior heat shock on the thermal resistance of listeria monocytogenes in meat was investigated. a sausage mix inoculated with approximately 10(7) l. monocytogenes per g was initially subjected to a heat shock temperature of 48 degrees c before being heated at a final test temperature of 62 or 64 degrees c. although cells heat shocked at 48 degrees c for 30 or 60 min did not show a significant increase in thermotolerance as compared with control cells (non-heat shocked), bacteria hea ... | 1990 | 2116757 |
| inhibitory effects of raw carrots on listeria monocytogenes. | the survival and growth of two strains of listeria monocytogenes on raw and cooked carrots stored at 5 and 15 degrees c and in carrot juice media at 30 degrees c were investigated. the influence of shredding, chlorine treatment, and packaging under an atmosphere containing 3% o2 and 97% n2 on the behavior of l. monocytogenes and naturally occurring microflora was determined. populations of viable l. monocytogenes decreased upon contact with whole and shredded raw carrots but not cooked carrots. ... | 1990 | 2116759 |
| monoclonal antibody specific for listeria monocytogenes, listeria innocua, and listeria welshimeri. | eight hundred fifty-nine murine hybridomas were produced from eight fusions, and 27 were characterized for secretion of antibodies reactive to listeria monocytogenes. one monoclonal antibody (mab), p5c9, reacted with all test strains of l. monocytogenes (31 of 31), l. innocua (3 of 3), and l. welshimeri (1 of 1) but not with any strains of the other four listeria species or with any of 22 gram-positive or 11 gram-negative species of bacteria when tested in microtiter and dot blot enzyme immunoas ... | 1990 | 2116762 |