Publications

[sudden death syndrome in infants in their first year of life; biological maturity and borderline conditions].		2007	2075054
[recurrent thromboembolism disclosing protein c deficiency. apropos of a case with familial investigation].	every thromboembolic manifestation, especially in young subjects, calls for an aetiological study in which haemostasis is evaluated primarily with assays of physiological coagulation inhibitors: protein c, protein s and antithrombin iii. protein c deficiency is found in 6 to 7% of thromboembolic manifestations. we report the case of a 21-year old man who had phlebitis followed by pulmonary embolism without facilitating factors. protein c level was 50% of normal value (0.50 iu/ml). the patient re ...	1990	2075365
[comparative study of 5 european tables of food composition (study of european tables of food composition)].	a comparative study has been made of the following nutritional data base: (a) c.s.i.c. (spain); (b) deutsche forschungsanstalt für lebensmittel chemie, garching; (c) inserm (france); (d) geigy; (e) wander. the following values were researched: calorie, protein, carbohydrate, fiber, calcium, iron, magnesium, vit. b1, vit b2, niacin, folic acid, vit. b12 and vit. c. in order to assess the use of these tables under different conditions, the following were researched: 1) a group of 10 essential repr ...	2007	2078596
[incidence and characteristics of q fever in a community habitat].	q fever is more common in our country than is usually thought, as shown by the diagnostic incidence curve, which approached an exponential rather than lineal function. sixty cases were diagnosed between 1985 and october 1989. the disease predominated in middle aged males. the suspect epidemiologic contacts did not have any significance. q fever was more frequent during autumn. its usual clinical presentation was pneumonia (75%), commonly associated with a flu-like syndrome. liver was commonly in ...	2006	2081169
[growth of coxiella burnetii in selected cell cultures].	usefulness of monolayer cell cultures for c. burnetii multiplication was evaluated. continuous vero cell line and primary cell (cultures cell culture of monkey kidney cercopithecus aethiops, cell culture of chicken fibroblasts, diploid cell line of human embryo) was inoculated for this purpose. two coxiella burnetii strains suspensions were used as inoculum of standard henzerling strain and zamość strain isolated from an area of poland. primary cell lines were characterized by considerable degre ...	1990	2087134
use of the acid-etch technique to maintain antimicrobial-containing acrylic resin strips in situ.	a technique that utilizes acid-etched composite resin to maintain antimicrobial-containing acrylic resin strips in situ is described. the advantage of this technique is that placement of a periodontal pack is unnecessary, so control of supragingival plaque is not hindered at the site of the local antimicrobial delivery. the technique described may improve the effectiveness and the clinical acceptability of local antimicrobials in the treatment of periodontal disease.	2002	2094868
the prefrontal cortex in schizophrenia and other neuropsychiatric diseases: in vivo physiological correlates of cognitive deficits.		2003	2094913
one-parameter item response theory models for psychomotor tests involving repeated, independent attempts.	three one-parameter item response theory models are given as viable models that describe the observed score probabilities of an examinee who takes a multiple attempts, single-item test of a psychomotor skill. these models include the binomial trials model, the poisson counts model, and the inverse binomial model. the paper presents these models and offers suggestions for their estimation and subsequent use in the assessment of psychomotor behavior.	2003	2094927
[in aino's ward comprehensive care is put to the test. interview by elisabet forslind].		2006	2095072
[crisis meeting in göteborg supports the rebels].		2006	2095092
[biochemical liver studies of workers in ethylenediamine production].	studies are performed on 44 workers, engaged in the production of ethylenediamine. the principle chemical noxae are: ammonia, ethylenediamine, dichloroethane, analogues of ethylenediamine, vinylchloride, sodium hydrate etc. the average concentrations of these compounds surpass the admissible norms for the air of the working environment. the biochemical studies certify for the presence of deviations in the enzymes, detoxication and lipidic liver functions. the established changes are observed in ...	2007	2099467
[coxiella burnetii: serologic study in various populations].	complement binding antibodies against coxiella burnetii were measured in 699 seric samples in order to ascertain the possible relationship between seric prevalence and the following factors: age, sex, living in rural or urban areas and socio-economical level. all patients were healthy: 180 were from a rural area 86 from guijo (cáceres); 36 from chiloeches (guadalajara) and 58 from bustarviejo (madrid); 519 were from an urban area (city of madrid). the samples from madrid city were classified by ...	1990	2104096
phase i and clinical pharmacological evaluation of a parenteral hexamethylmelamine formulation.	hexamethylmelamine has been evaluated in single agent and combination regimen studies for many years, but only following p.o. administration. pharmacological studies in animals and humans have shown that systematic availability of parent drug following p.o. administration is relatively low and variable due to extensive first-pass metabolism rather than due to poor absorption. two phase i clinical trials, with accompanying pharmacokinetic studies, have been conducted by using a parenteral formula ...	2007	2104537
[evan's syndrome and pseudolupic circulating anticoagulants during endocarditis with q fever].		1990	2108602
the changing pattern of antibiotic resistance of neisseria gonorrhoeae.		1990	2111274
the changing pattern of antibiotic resistance of neisseria gonorrhoeae.		1990	2111274
nucleotide sequence of htpb, the legionella pneumophila gene encoding the 58-kilodalton (kda) common antigen, formerly designated the 60-kda common antigen.	gene htpb, which encodes the 58-kilodalton protein of legionella pneumophila, was cloned in escherichia coli and its complete nucleotide sequence was determined. analysis of this sequence revealed an open reading frame of 1,644 nucleotides encoding a protein with a predicted molecular mass of 57,952 daltons. data obtained by amino-terminal sequencing of the purified 58-kilodalton protein agreed, except for one amino acid residue, with the predicted amino acid sequence, identifying this open read ...	1990	2117582
zoonotic infections in northern ireland farmers.	evidence of past zoonotic infection was investigated serologically in randomly selected northern ireland farmers. the percentage of farmers with antibody was: brucella abortus (0.7), leptospira interrogans serovars (8.1), borrelia burgdorferi (14.3), toxoplasma gondii (73.5), coxiella burnetii (28.0), chlamydia psittaci (11.1) and hantavirus (1.2). the results show that northern ireland farmers have been exposed in the past to zoonotic infections. it is not known if these infections contributed ...	1990	2123457
prevalence of antibodies to rickettsia conorii coxiella burnetii and rickettsia typhi in salamanca province (spain). serosurvey in the human population.	the salamanca province of spain is an endemic zone for mediterranean spotted fever. in this area, only one case of q fever has been reported and typhus group rickettsial diseases have never been diagnosed. to obtain a panoramic view of the presence of antibodies to the most ubiquitous rickettsial agents, 400 sera specimens from a statistically representative sample of the human population of salamanca city and its surrounding province were subjected to indirect microimmunofluorescent test for an ...	1990	2123799
[q fever. a familial outbreak of 5 cases].	five cases of acute q fever diagnosed in the same family are reported. the epidemiological and clinical features, the therapy and evolution of the infections by coxiella burnetti are discussed. q fever is a condition to be considered in febrile illnesses or atypical pneumonia, particularly when developing in outbreaks. it is concluded that q fever should be considered as endemic in some areas of this country (basque country, catalonia...). finally, we think that antibiotic therapy (tetracyclines ...	1990	2129681
q fever in israel.	q fever was first described over fifty years ago. while in a proportion of cases there is a clear etiologic link to farm animals, their products, and fomites, in the majority of cases no such association is apparent, and the mode of infection is a mystery.	2017	2134719
[acute hepatitis as the presenting form of q fever].		2004	2152493
[necrotizing myositis caused by coxiella burnetii].		1990	2152494
reduction of drug accumulation and dna topoisomerase ii activity in acquired teniposide-resistant human cancer kb cell lines.	we have isolated stable teniposide (vm26)-resistant cell lines from human cancer kb cells by stepwise exposure to increasing doses of the drug. at each step, we have purified vm26-resistant cell lines. kb/vm-a, kb/vm-b, kb/vm-1, kb/vm-2, kb/vm-3, and kb/vm-4 showed 3-, 6-, 12-, 16-, 74-, and 95-fold higher resistance to vm26 than did kb. we have further characterized kb/vm-2 and kb/vm-4 which showed about 15- and 100-fold higher resistance to vm26 or etoposide (vp16) than did kb. both vm26-resis ...	1990	2168282
morphological aspects of inhibition of transformation of rat kidney cells infected with a temperature-sensitive mutant of the rous sarcoma virus by rat fibroblast interferon.	normal rat kidney cells (nrk) infected with a temperature-sensitive (ts) mutant of rous sarcoma virus (rsv) at the permissive temperature (33 degrees c) exhibit the morphological and growth characteristics of the transformed state. by the use of this system, it has been shown that the addition of rat fibroblast interferon to infected cells grown at a nonpermissive temperature (38 degrees c) prevents re-transformation when they are introduced to the permissive temperature. merely treating cells a ...	1990	2168311
in vitro cytotoxic effects of cobalt-containing dusts on mouse peritoneal and rat alveolar macrophages.	"hard metal disease" is a chronic lung disease characterized by the presence of interstitial fibrosis; the role of cobalt in the development of this entity is still debated. indeed, most cases have been observed in some workplaces (grinding) of the hard metal industry and in the diamond polishing industry whereas no similar cases have been reported from workers exposed to pure cobalt powders in cobalt refineries. this study was designed to assess the in vitro toxicity (ldh release, morphology) o ...	1990	2168316
optimization of filtration for reduction of lung dose from rn decay products: part i--theoretical.	a theoretical model was developed for the optimization of filter characteristics that would minimize the dose from the inhalation of rn decay products. modified forms of the jacobi-porstendorfer room model and the jacobi-eisfeld lung dose model were chosen for use in the mathematical simulation. optimized parameters of the filter were the thickness, solidity, and fiber diameter. for purposes of the calculations, the room dimensions, air exchange rate, particle-size distribution and concentration ...	2007	2168348
impact of reduced cytochrome oxidase activity on peak oxygen consumption of muscle.	the impact of reduced muscle oxidative capacity on peak oxygen consumption and isometric performance was evaluated using an isolated rat hindlimb preparation perfused with a high oxygen delivery. capacity for electron transport was reduced with chloramphenicol (cap), an inhibitor of mitochondrial gene-coded protein synthesis. the activity of cytochrome oxidase, a mitochondrial cristae component, was reduced approximately 45% (p less than 0.005) in the mixed-fiber-type plantaris muscle. several f ...	1990	2168365
[primary mediastinal germ cell tumors].	the most frequent site of extragonadal germ cell tumors is the mediastinum. the majority (80%) of mediastinal germ cell tumors are benign mature teratomas, which can be easily removed. malignant germ cell tumors account for approximately 20% of all cases and are clinically classified into seminoma and non-seminomatous germ cell tumors. seminomas are radiosensitive and have relatively a good prognosis. patients with non-seminomatous germ cell tumors had a very poor prognosis, however, the introdu ...	2007	2168496
in vitro assembly of relaxosomes at the transfer origin of plasmid rp4.	during initiation of conjugative transfer of dna containing the transfer origin (orit) of the promiscuous plasmid rp4, the proteins trai, traj, and trah interact and assemble a specialized nucleoprotein complex (the relaxosome) at orit. the structure can be visualized on electron micrographs. site- and strand-specific nicking at the transfer origin in vitro is dependent on the proteins trai and traj and on mg2+ ions. substrate specificity is directed exclusively towards the cognate transfer orig ...	1990	2168553
[the prevention of the intracranial hypertension due to general anesthesia during operations on the brain].	the article deals with the analysis of changes in cerebrospinal fluid pressure (csfp), mean arterial pressure (map), brain perfusion pressure (bpr), and central venous pressure (cvp) during general anesthesia in 172 patients with tumorous, tumor-like, and vascular diseases of the brain. csfp increased sharply during preanesthesia, in administration of inhalation anesthetics, and under the effect of inadequate anesthesia during trephination of the skull. the rise in csfp in preanesthesia can be r ...	2007	2168649
effect of inhibition of na+/k(+)-adenosine triphosphatase on vascular action of vasopressin.	the present study was undertaken to examine the cellular interaction between a na+/k(+)-atpase inhibitor, ouabain, and arginine vasopressin (avp) in rat vascular smooth muscle cells (vsmc) in culture. preincubation with 10(-5) m ouabain for 60 min increased basal cytosolic free ca2+ [( ca2+]i) concentration and intracellular 45ca2+ uptake. ouabain, however, did not affect basal 45ca2+ efflux or avp-stimulated 45ca2+ efflux. as assessed by cell shape change, preincubation with 10(-5) m ouabain fo ...	1990	2170449
a randomized, controlled, double-blind, cross-over, clinical trial of q fever vaccine in selected queensland abattoirs.	a limited, randomized, blind, placebo-controlled trial of q fever and influenza vaccines has been conducted in three queensland abattoirs on a sequential analysis design. ninety-eight subjects were given q fever vaccine and 102 influenza vaccine. q fever cases were observed in unvaccinated workers in all three abattoirs during the period of observation. a total of seven q fever cases in one group, one more than the number required to achieve statistical significance between the two vaccine group ...	1990	2182329
[laboratory diagnosis of respiratory syncytial virus infection].	we study 18 children with acute respiratory infection diagnosed early by direct immunofluorescence (dif) using monoclonal antibodies to synticial respiratory virus (srv). antibodies to adenovirus, influenza virus a and b, parainfluenza virus 1, 2 and 3, mycoplasma, q fever, herpes and cytomegalovirus (cmv) are also studied. we consider that in most cases the diagnosis of infections caused by srv cannot be established by complement fixation, and should be accompanied by some antigen detection tec ...	1990	2189329
color duplex imaging and doppler spectrum analysis: principle, capabilities, and limitations.		1989	2189468
the immune response in a cat-related outbreak of q fever as measured by the indirect immunofluorescence test and the enzyme-linked immunosorbent assay.	the isotypic immune response of 16 individuals who developed q fever pneumonia following exposure to an infected parturient cat was studied. the enzyme-linked immunosorbent (elisa) test was used to detect igm, iga, and igg antibodies to phase i and phase ii coxiella burnetii whole-cell antigens and to the phase i lipopolysaccharide. the indirect immunofluorescent antibody (ifa) test was also used to detect antibodies to phase i and phase ii whole cells. none of the 16 subjects developed antibodi ...	1990	2192785
adolescent substance use and the role of the primary care provider.		2000	2193360
t-cell lymphoma after heart transplantation.	a 26-year-old woman who had undergone orthotopic heart transplantation because of dilative cardiomyopathy received a triple-drug immunosuppressive regimen (cyclosporine a, azathioprine, and prednisolone). during her relatively frequent episodes of acute rejection, she was treated with methylprednisolone and repeated application of atg. a short time before the patient's death, a fine-needle aspiration of the liver revealed the cytologic diagnosis of a malignant pleomorphic medium-size cell non-ho ...	2001	2193510
induction of heat-shock proteins in coxiella burnetii.		1990	2198830
host factors in the severity of q fever.	the author has reviewed different aspects of the role of immunocompetence in the development of q fever. coxiella burnetii lives within the phagolysosomes of infected cells. in animals, the immunosuppression caused by either cortisone or x-irradiation reactivates q fever. in humans, cases of q fever are reported in immunocompromised hosts suffering from leukemia, cancer, and human immunodeficiency virus infection (aids). similar data are reported with strict or facultative intracellular parasite ...	1990	2198833
characterization of the origin of dna replication of the coxiella burnetii chromosome.		1990	2198835
similarity in pathogenic features in lung and peritoneal infection by coxiella burnetii, typhus group rickettsiae, and chlamydiae.		1990	2198836
legionella pneumophila htpab heat shock operon: nucleotide sequence and expression of the 60-kilodalton antigen in l. pneumophila-infected hela cells.	a 60-kilodalton (kda) immunodominant antigen of legionella pneumophila is a heat shock protein (hsp) of the groel class of hsps. the gene (htpb) coding the 60-kda protein was localized to a 3.2-kilobase dna fragment of l. pneumophila cloned into puc19 (psh16) (p. s. hoffman, c. a. butler, and f. d. quinn, infect. immun. 57:1731-1739, 1989). the nucleotide sequence of the dna fragment cloned into m13 confirmed two open reading frames, htpa and htpb, that code for proteins of 96 and 548 amino acid ...	1990	2205580
importance of the portal venous pathway to the transport of intestinal triglyceride-rich lipoproteins in the preruminant calf.		1990	2206345
prevalence of q fever infection in the addis ababa abattoir.	a total of 465 human sera were collected for a serological survey of q fever infection from the addis ababa, ethiopia, abattoir, in 1988. the subjects' sera were tested for antibodies against coxiella burnetti antigen using the complement fixation test. results indicate a prevalence rate of 6.5%. this finding clearly demonstrates serological evidence of post infection with q fever in employees of the abattoir.	1990	2209579
q fever in plymouth, 1972-88. a review with particular reference to neurological manifestations.	between 1972 and 1988 we have serologically confirmed 103 coxiella burnetii infections: 46 were acute, 5 were chronic, 52 represented past infections. details of 61 cases are presented. of acute cases 80% had respiratory involvement; at least 63% had pneumonias. the incidence (22%) of neurological complications was of particular interest; 40% of these patients had prolonged sequelae. one acutely ill patient died of fulminating hepatitis. patients with pre-existing pathology or immunosuppression ...	1990	2209742
survey of cardiac rehabilitation centers in new york city.	out-patient cardiac rehabilitation centers in new york city were surveyed in order to determine current practices. all 24 centers operating as of may, 1987 were sent questionnaires; 16 responded for a return rate of 67 percent. in general, practices of the centers were in accord with guidelines of the american heart association (aha) and the american college of sports medicine. the incidence of medical complications in the centers was quite rare, perhaps accounting for the failure of centers to ...	1998	2212093
philippine population development: a nursing concern.	in keeping with nurses' commitment to the preservation and care of human life, population development should be a major concern of the nursing profession in the philippines. the profession should ensure that the health system is oriented toward people's needs and formulate manpower strategies on the basis of these needs and population distribution. nurses are in an ideal position to advocate a family-centered approach to health care through their access to pregnant women and mothers. nurses c ...	1990	2217534
evolution of deep venous thrombosis: a prospective evaluation with us.	forty-six patients with a diagnosis of acute deep venous thrombosis (dvt) established by means of duplex ultrasound (us) were prospectively followed up with serial duplex us examinations during a 6-month period to assess the persistence of venous abnormalities. all patients were asymptomatic. isolated popliteal dvt was found to be more likely to revert to normal at duplex compression us than thrombosis involving both the femoral and popliteal systems (p less than .05). increased venous diameter ...	1955	2217798
[magnetic resonance in the study of cardiac dysplasia].		1955	2217931
bactericidal effect of doxycycline associated with lysosomotropic agents on coxiella burnetii in p388d1 cells.	there is no consistently reliable treatment for endocarditis resulting from chronic coxiella burnetii infection, the causative agent of q fever. although certain antibiotics are recommended on the basis of their in vitro bactericidal activities, results of therapy with these antibiotics are often disappointing. to evaluate whether the currently recommended antibiotic susceptibility tests for c. burnetii give misleading results because of continued division of uninfected cells, thereby resulting ...	1990	2221859
humoral factors determining the blood pressure response to converting enzyme inhibition and calcium channel blockade.	renin and catecholamine levels were determined in patients with mild to moderate hypertension before and after treatment with sustained release diltiazem or captopril and were correlated with the blood pressure response to these antihypertensives. eight weeks of treatment with either agent led to equal decreases in both systolic and diastolic blood pressure. pretreatment plasma renin activity (pra) and plasma norepinephrine did not predict the blood pressure response to either agent. diltiazem s ...	2008	2222951
thermodynamic properties of globular proteins and the principle of stabilization of their native structure.	a semi-empirical method has been used to estimate the thermodynamic parameters of hydration of buried surface areas of ribonuclease s, lysozyme and myoglobin from the model of complete unfolding according to ooi et al. ((1987) proc. natl. acad. sci. usa 84, 3086-3090). the buried surface area of proteins is considered as the difference between the accessible surface area of native protein and the completely extended polypeptide chain according to lee and richards ((1971) j. mol. biol. 55, 379-40 ...	2008	2223840
occurrence of coxiella burnetii, rickettsia slovaca, and organisms resembling bacillary rickettsiae in their natural foci in slovakia 20 years after their first detection.		1990	2227718
abelson murine leukemia virus transforms preneoplastic emu-myc transgene-carrying cells of the b-lymphocyte lineage into plasmablastic tumors.	e mu-myc transgenic mice were back-crossed to balb/c mice up to back-cross generation 3. the offspring that included transgene-carrying and -negative mice in approximately equal proportions were randomly divided into 2 groups. thirty-four mice (group i) were treated with pristane, followed by a-mulv, and 40 (group ii) were injected with a-mulv alone. altogether, 16 lymphoid tumors developed in group i and 17 in group ii. nine of the tumors in group i and 4 in group ii appeared as ascitic tumors. ...	1990	2228313
stereotactic radiation for intracranial arteriovenous malformations.		2008	2233958
the work of pediatric residents.		1987	2235245
[meningoencephalitis caused by coxiella burnetii].	meningoencephalitis caused by coxiella burnetii is exceptional and its clinical presentation is varied. we report a case which presented as transient central neurological deficits and intracranial hypertension without fever. the condition was diagnosed by indirect immunofluorescence.	1990	2237097
acute respiratory disease in spain: seven years of experience.	the clinical and epidemiologic features of viral and nonviral pathogens involved in acute respiratory diseases are described in the context of cases of infection (especially atypical pneumonia and bronchiolitis) studied at the centro nacional de microbiología, virología e immunología sanitarias in madrid during a 7-year period (1979-1986). these etiologies were demonstrated in 1,637 (36.2%) of 4,521 cases. among viruses, respiratory syncytial virus most frequently infected children; influenza vi ...	1990	2237112
[effect of enalapril on heart rate, arterial blood pressure and exocrine pancreatic secretion in the alert dog].	a changed exocrine pancreatic secretion could be a pathogenetic factor of an acute pancreatitis after administration of angiotensin-converting enzyme (ace) inhibitors. in six conscious dogs with gastric and duodenal thomas fistulas we studied the effect of an intravenous (iv.) bolus injection of 10 mg enalaprilat, an intraduodenal (id.) bolus injection of 20 and 40 mg enalapril (e.), and 0.15 m nacl (20 ml iv., resp., id.) on pancreatic bicarbonate- and protein output in response to secretin (20 ...	1990	2238764
[perioperative ultrasound examination of the breast in breast cancer].	127 cases of breast carcinoma were examined in a prospective study. by means of preoperative ultrasonography the staging following the ptnm-system validates the tumor size in 85.5% and the lymph node involvement in 77.2%. multicentric-multifocal carcinomas were diagnosed by ultrasonography in 20 of 29 cases, merely 9 of 29 by mammography. ultrasonography of specimen is recommended in cases of negative clinical findings and positive ultrasound examination to verify tumour excision. in addition to ...	2007	2238972
[perioperative ultrasound examination of the breast in breast cancer].	127 cases of breast carcinoma were examined in a prospective study. by means of preoperative ultrasonography the staging following the ptnm-system validates the tumor size in 85.5% and the lymph node involvement in 77.2%. multicentric-multifocal carcinomas were diagnosed by ultrasonography in 20 of 29 cases, merely 9 of 29 by mammography. ultrasonography of specimen is recommended in cases of negative clinical findings and positive ultrasound examination to verify tumour excision. in addition to ...	2007	2238972
nucleotide sequence of coxiella burnetii superoxide dismutase.		1990	2243797
barotrauma associated with high-frequency jet ventilation for hypoxic salvage.	most reports describe reduction in proximal airway pressures with high-frequency jet ventilation. this led us to speculate that high-frequency jet ventilation might reduce barotrauma by providing alveolar ventilation at lower airway pressures. we describe a group of patients in whom a high incidence of barotrauma was observed after institution of high-frequency jet ventilation despite reduction in measured airway pressures. fifteen hypoxic patients who could not be treated with conventional vent ...	2008	2244805
[hibernal respiratory disorders].	a long term serological surveillance of the acute respiratory illnesses was conducted, looking for infections by adenoviruses, influenza a.b.c. parainfluenza 1,2,3 and respiratory syncytial viruses as well as mycoplasma pneumoniae, coxiella burneti and chlamydia psittaci. the analysis of the results accumulated for the past 20 years was carried out. influenza c. coxiella burneti and chlamydia psittaci infections were rare and could not account for any epidemic prevalence. the other agents produc ...	1990	2249087
[pulmonary changes in progressive systemic sclerosis].	the pulmonary changes of progressive systemic sclerosis in 8 cases were reported. the major clinical complaints were unproductive cough and exertional dyspnea. pulmonary function tests showed restrictive ventilatory defects and impaired diffusing capacity in most of the cases examined. on chest x-rays, diffuse mottling and linear densities were seen in lungs, predominately in the basal regions. on pathological examinations, pulmonary interstitial fibrosis occurred in early stage of the disease. ...	1989	2249319
isolation of 16 strains of coxiella burnetii from patients by using a sensitive centrifugation cell culture system and establishment of the strains in hel cells.	q fever, caused by coxiella burnetii, may be acute or chronic. only a few strains of c. burnetii have been isolated due to the difficulty and hazard of isolation. we report here the isolation using a centrifugation shell vial technique of 16 new strains from patients suffering chronic q fever. twenty-four samples were inoculated onto human embryonic lung (hel) fibroblast cell monolayers growing in shell vials. c. burnetii was detected 6 days later by using immunofluorescence. samples from valves ...	1990	2254424
molecular identification of major and minor bullous pemphigoid antigens.	the skin antigens defined by basement membrane zone antibodies in 38 patients with bullous pemphigoid were analyzed by western immunoblot. thirty-four patients (89%) had antibodies to a major bullous pemphigoid antigen with a molecular weight of approximately 230 kd. twelve patients (32%) had antibodies to a minor bullous pemphigoid antigen with a molecular weight of approximately 160 kd; this included four patients who did not have antibodies to the 230 kd antigen. depending on the epidermal ex ...	2007	2254473
molecular identification of major and minor bullous pemphigoid antigens.	the skin antigens defined by basement membrane zone antibodies in 38 patients with bullous pemphigoid were analyzed by western immunoblot. thirty-four patients (89%) had antibodies to a major bullous pemphigoid antigen with a molecular weight of approximately 230 kd. twelve patients (32%) had antibodies to a minor bullous pemphigoid antigen with a molecular weight of approximately 160 kd; this included four patients who did not have antibodies to the 230 kd antigen. depending on the epidermal ex ...	2007	2254473
drinking, the construction of ethnic identity and social process in a western australian youth subculture.	this paper presents an anthropological analysis of the meaning of drinking for the male members of the skinhead youth subculture in perth, western australia. perth skinheads are an exported and modified form of the original english skinhead subculture. using participant observation as the primary research method, the style of drinking is analysed as one of the ways in which the members of this subculture express their english ethnicity and constitutive of the social processes which underpin the ...	2008	2265287
induction of carcinoembryonic-antigen-gene expression in human colorectal carcinoma by sodium butyrate.	the effect of sodium butyrate on the expression of the carcinoembryonic-antigen (cea) gene was studied in two poorly differentiated colorectal-carcinoma cell lines (clone-a and mip-101) and in one well-differentiated cell line (ls-174t); a.t.c.c. no. ccl 188). northern-blot and dot-blot analyses indicated a steady increase in cea mrna from day 4 to a maximal level by day 14 after these cells were exposed to 2 mm-sodium butyrate. studies using nuclear run-off assays followed by dot-blot hybridiza ...	1990	2268282
technical variability of bone histomorphometric measurements.	effects of main sources of bone biopsy sample variability have been examined. variability was assessed in double iliac crest biopsies of 12 subjects with normal or pathological bone. components of variance were estimated as follows: two biopsies per patient; three specimens at different distances from compact bone; three sections per specimen; three microscopic fields per section. the following indicators were measured: bone volume (bv/tv); osteoid volume (ov/bv); osteoid surface (os/bs); osteob ...	2008	2268745
placental transfer and tissue distribution of vitamin e in pregnant rabbits.	alpha-tocopherol (vitamin e) is widely prescribed in neonatal intensive care units, in large doses and by different schedules, for the prevention of retrolental fibroplasia, intraventricular haemorrhage, bronchopulmonary dysplasia, and haemolytic anaemia. since the efficacy of the drug in premature newborns seems related to early administration, the physicochemical characteristics of the drug itself and available formulations limit the major therapeutic aim of promptly raising levels of vitamin ...	1990	2271744
growth of normal versus leukemic bone marrow cells in long term culture from acute lymphoblastic and myeloblastic leukemias.	the ability of the in vitro long-term bone marrow culture (ltbmc) system to impair the survival of leukemic cells and to enhance the growth of normal progenitors has been studied. bone marrow cells from 19 acute lymphoblastic leukemia (all) and 30 acute myeloid leukemia (aml) patients at diagnosis were grown in ltbmc for 4-10 weeks. in half of the cases the leukemic population declined down to undetectable levels and was replaced by putative normal hemopoietic precursors, both in all and in aml. ...	1990	2271773
cultured composite skin grafts for burns.		1990	2271878
future funding policies from non-government sources: the wellcome trust.	as we enter the 1990s, the trust is taking on a new and unsought role as a mainstay of university biomedical research. it is to be hoped that recent statements from government, which appear to recognize the harm being wreaked on the universities, will prove to be more than pious platitudes.	2008	2276426
immunization of cattle (bos indicus x bos taurus) against hyalomma anatolicum anatolicum using antigens derived from tick salivary gland extracts.	studies were conducted on 41 cross-bred (bos taurus x bos indicus) calves which were less than 1 year old. three types of salivary gland antigens (sg ag) viz. sg ag-i (whole), sg ag-ii (supernatant) and sg ag-iii (sediment), prepared from the ixodid tick, hyalomma anatolicum anatolicum, were used for immunizing these calves. the calves were divided into five groups. the first three groups were immunized with sg ag-i, -ii and -iii with freund's complete adjuvant (fca), respectively. the fourth gr ...	1990	2276870
clinical q fever in northern ireland 1962-1989.	q fever was diagnosed in 443 patients in northern ireland between 1962 and 1989. from 1986 onwards there was an increase, which peaked in 1989 with 107 cases of whom 47 were infected in ballycastle, co antrim. there were three outbreaks and 21 clusters of patients with q fever. most cases were in april and may which correlated with the peak lambing and calving season. q fever mainly affected males in the 40-49 year old age group. county antrim had the highest prevalence rate of 40/100,000 popula ...	1990	2278109
[q fever and pulmonary thromboembolism].		2004	2284492
[clinical manifestations of acute q-fever].	the participation of asymptomatic infections and clinical forms of acute q-fever were analysed, using the active epidemiological investigation of the population affected by q-fever epidemics. out of the total number of registered q-fever cases, the asymptomatic infection was present in 8.36%. the occurrence of asymptomatic infection was statistically more frequent by significance in women than in men. pulmonary form of q-fever occurred in 65.20% of the diseased. this clinical manifestation was s ...	2004	2287302
[frequency of abortion and seroprevalence of the principal diseases causing ovine infectious abortion in the area of rabat (morocco)].	a survey was carried out on 23 sheep flocks to estimate the frequency of abortion as well as the prevalence of antibodies against abortive infections. during the visit of each farm, a questionnaire was completed with the collaboration of the owner and blood samples were collected from all aborted ewes and some of those with normal lambing. a rate of 7% abortion was reached in both aborted and normally lambed ewes. anti-chlamydia psittaci antibodies were the most frequently detected (14 flocks). ...	1990	2288452
[a tonsillolith].	the author describes a tonsillolith accidentally detected in a peritonsillar abscess in a 10-year-old girl. the concrement 26 x 4 mm in size, weighing 0.84 g was analyzed by infrared spectroscopy, x-ray diffraction which revealed that it was a dahllite. the surface of the concrement was documented by a scanning microscope. the authors give an account of 29 published cases of tonsilloliths and in the discussion they analyze the causes of development of these concrements in tonsils.	2007	2292111
[a tonsillolith].	the author describes a tonsillolith accidentally detected in a peritonsillar abscess in a 10-year-old girl. the concrement 26 x 4 mm in size, weighing 0.84 g was analyzed by infrared spectroscopy, x-ray diffraction which revealed that it was a dahllite. the surface of the concrement was documented by a scanning microscope. the authors give an account of 29 published cases of tonsilloliths and in the discussion they analyze the causes of development of these concrements in tonsils.	2007	2292111
hepatitis b surface antigen seroconversion in resident doctors.		2008	2292578
a prospective study of viral and mycoplasma infections in chronic inflammatory bowel disease.	seventy-two children with chronic inflammatory bowel disease were investigated for infections with various viruses and mycoplasma pneumoniae, chlamydia psittaci, and coxiella burnetii to determine whether these pathogens are associated with acute onset exacerbations. altogether 54 infections were identified serologically, of which 23 (42.6%) were associated with exacerbations. this corresponded to 24.2% of the recorded exacerbations during the study period. the respiratory pathogens accounted fo ...	1990	2298361
q fever--sexually transmitted infection?		1990	2299222
acute q fever.		1990	2310295
women's work and working women: childcare and the nhs.		2008	2312325
[lung infections with atypical features].	the clinical difference between a lobar pneumonia caused by pneumococci or other bacterial agents and lower respiratory tract infections presenting with atypical symptoms is important. mycoplasma pneumoniae, chlamydia species, coxiella burnetii and several viruses amongst others are micro-organisms which cause atypical symptoms. all the time new types of micro-organisms like ureaplasma urealyticum are found as a cause of pneumonia with atypical symptoms. special diagnostic tools like cultures, s ...	1990	2315905
q fever encephalitis.	encephalitis is a rare but documented complication of acute q fever. we report here the case of a 48-year-old lady who presented with an acute illness characterised by influenza-like symptoms, pneumonia and neurological disturbance but in whom the serology was suggestive of chronic rather than acute q fever.	1990	2319148
intrathoracic lymphadenopathy. a rare manifestation of rheumatoid pulmonary disease.	this is the first antemortem report of a patient with long-standing ra and interstitial lung disease who developed reactive mediastinal adenopathy coincident with increases in the activity of his interstitial process. mediastinal adenopathy was discovered by means of ct of the chest as part of an evaluation of interstitial lung disease. the increasing use of better imaging techniques for this purpose will undoubtedly reveal more patients with this finding. mediastinal lymphadenopathy complicatin ...	2007	2323235
vaccine prophylaxis of abattoir-associated q fever: eight years' experience in australian abattoirs.	during the period 1981-8 a clinical trial of a q fever vaccine (q-vax; commonwealth serum laboratories, melbourne) has been conducted in abattoir workers and other at-risk groups in south australia. volunteers in four abattoirs and visitors to the abattoirs were given one subcutaneous dose of 30 micrograms of a formalin-inactivated, highly-purified coxiella burnetii cells, henzerling strain, phase 1 antigenic state, in a volume of 0.5 ml. during the period, over 4000 subjects have been vaccinate ...	1990	2323360
nucleotide sequence of porcine insulin-like growth factor. 1:5' untranslated region, exons 1 and 2 and mrna.		1990	2326169
[endocarditis caused by coxiella burnetii in aortic prosthesis. presentation of a case with a fatal course].	a case of endocarditis caused by coxiella burnetii in a patient with an aortic starr-edwards prosthesis is described. the diagnosis was made by detecting high titres of antibody against coxiella burnetii phase i antigens. after 15 weeks of chemotherapy with tetracycline and cotrimoxazole, aortic prosthetic valve replacement was carried out because of haemodynamic deterioration and he died 4 days later. the histologic picture of the excised valve was consistent with endocarditis. coxiella burneti ...	1990	2326533
[q fever with dilatation of liver sinusoids and a long course].		1990	2330435
contrast dependence of short-range apparent motion.	the apparent motion of band-pass filtered random dot kinematograms was assessed by measurements of two alternative direction discrimination performance. in the case of two-dimensional (isotropically filtered) stimuli, the results were largely independent of contrast: at michelson contrasts of 5 and 50%, near-perfect direction discrimination was obtainable for a limited range of displacements. however for one-dimensional (grating) stimuli, apparent motion seems to be highly dependent on contrast. ...	2008	2336804
[neoplasms of the meckel diverticulum. apropos of 2 new cases].	we present two new cases of cancer in a meckel's diverticulum, representing 3.3% of the complicated meckel's diverticula encountered in our department. the first case was a carcinoid tumor encountered in a pathology study of an inflamed meckel's diverticulum, and the second case was a leiomyosarcoma on a meckel's diverticulum that presented as diverticular perforation. we emphasize the advanced age of the two patients and review the cases reported in spain and in the western literature.	2008	2346684
an epidemiological study of an outbreak of q fever in a secondary school.	five cases of clinical q fever were identified amongst students and staff of a somerset secondary school between 23 october 1987 and 21 december 1987. five goats which were kept at the school were found to have antibodies to coxiella burnetii phase ii. a cross-sectional study was conducted at the school in july 1988. a single cf test was used to identify evidence of prior infection, and a self-administered questionnaire was used to collect data on exposure variables and illness during 1987. four ...	1990	2347385
the children of teenage mothers: patterns of early childbearing in two generations.	twenty years after a mostly black group of baltimore women became adolescent mothers, the majority of their first-born children had not become adolescent parents, a finding that challenges the popular belief that the offspring of teenage mothers are themselves destined to become adolescent parents. almost all of the offspring had had intercourse by age 19. about half of the young women had experienced a pregnancy before that age, and approximately one-third of the young men reported having impre ...	2008	2347409
mixed infection of rickettsiella phytoseiuli and coxiella burnetii in dermacentor reticulatus female ticks: electron microscope study.	mixed infection of rickettsiella phytoseiuli and coxiella burnetii was investigated in hemolymph and organs of experimentally infected females of dermacentor reticulatus ticks. following intracoelomic infection, both agents, with the exception of gene's organ, multiplied well in the cells of the tick host's organs. two out of six developmental stages of r. phytoseiuli, i.e., crystal-forming and small dark particles, in dual infection with c. burnetii revealed marked morphological alterations. c. ...	1990	2351845