Publications

predictive value of a short dietary questionnaire for changes in serum lipids in high-risk utah families.	dietary questionnaires and serum cholesterol, triglycerides, and high-density lipoprotein (hdl) cholesterol determinations were completed for 1239 subjects aged greater than or equal to 20 at each of two separate screenings. the mean time between screenings was 2.5 y. after correcting for potential confounding variables, reduction of a measure of dietary cholesterol and saturated fatty acids assessed by two simple questions was a significant independent predictor of reduction in total cholestero ...	2009	2756916
attempted passive transfer of a serum factor in chronic urticaria from human to monkey.		1989	2757947
effects of public day-care: a longitudinal study.	119 swedish children were followed from their first year of life up to the age of 8. most could be classified according to (a) type of day-care they had experienced during their first 7 years of life and (b) time of first entrance into day-care. at 8 years, the children were tested with aptitude tests and rated by their teachers on school performance and social and personal development. hierarchical regression analyses and mancovas were used in the statistical treatment. time of entrance into da ...	2009	2758882
hypersensitivity myocarditis and hepatitis associated with imipramine and its metabolite, desipramine.	we present two cases of myocarditis and hepatitis with histologic characteristics of hypersensitivity-mediated drug reactions associated with imipramine and its metabolite, desipramine. in one case, death was directly attributed to myocarditis; in the second case, the patient died of an acute myocardial infarct, but myocarditis may have played a contributory role. one patient was taking imipramine, and therapeutic concentrations of imipramine and desipramine were documented in postmortem blood. ...	2009	2760582
2-bromo- and 16-bromo-estrogens and related compounds: potential inhibitors for both estradiol 2- and 16 alpha-hydroxylases in rat liver microsomes.	kinetic studies of inhibition of estradiol 2- and 16 alpha-hydroxylase activities in male rat liver microsomes with 2-bromoestrogens, 4-bromo-estrone (4-bre1), 16 alpha- and 16 beta-bromoestrones and 16 beta-acetylthioestrone (16-acse1) were carried out. 2-bromoestrogens and 4-bre1 nonspecifically blocked the two enzyme activities in a competitive manner, and 2-bromo-estradiol (2-bre2) was the most potent inhibitor for the two hydroxylases among the 2- and 4-bromo steroids. kinetic data, the app ...	1989	2761259
transcriptional start site in the mouse cyp1a1 (cytochrome p1450) gene.	two transcriptional initiation sites have been described by different laboratories for the mouse cyp1a1 (cytochrome p1450) gene: start site ti, at the beginning of the nontranslated 87-bp first exon, and start site tii, 635 bp downstream from site ti within the 2,380-bp first intron. site ti was characterized in normal c57bl/6 mouse liver, whereas site tii was described in a high activity variant line (hav cells) derived from the mouse hepatoma hepa-1c1c7 wild type (wt) established cell line. it ...	1989	2766934
organization of positional information in the axolotl limb.	we have used the phenomenon of position-dependent growth stimulation, brought about by the confrontation of cells with dissimilar positional values, to reveal the organization of positional information in the center of the upper and lower arms of axolotls. when either humerus or radius was transplanted into either dorsal or posterior positions, extra growth leading to the formation of supernumerary digits occurred following amputation through the graft. however, transplants of humerus or radius ...	2009	2769199
[periapical lesions treated with cao. histological controls].	the results of histological examinations conducted on 2 granulomas found in teeth and treated with calcium oxide are reported. it is concluded that the treatment produces significant changes in the histological picture with the formation of scar tissue that precedes the growth of newborn in a relatively short time.	2009	2770661
[cardiovascular risk factors in children and adolescents in fuenlabrada: objectives, features of the population, design, participation, equipment, laboratory technics, and quality control].	fuenlabrada is at the present time the most industrialized town placed at the south are of madrid. this population has some peculiar attractive characteristics from the epidemiologic point of view. perhaps the most important is that the majority of its inhabitants are immigrant from other depressed rural areas of the country, with a low socio-economic and cultural level. the new conditions of life could have changed the life expectation and the causes of morbidity and mortality of this populatio ...	1989	2772364
membrane fatty acids and erythrocyte li-na countertransport in nephrotic syndrome and their relationship.	cholesterol/phospholipids molar ratio and fatty acid composition have been estimated in erythrocyte membrane of 12 patients suffering from nephrotic syndrome and compared to values obtained in 23 normal subjects matched for sex and age. the membrane lipid composition has been correlated with the activity of erythrocyte li-na countertransport of the same subjects. the results show a significant increase in cholesterol/phospholipids ratio and total saturated fatty acids when erythrocytes of nephro ...	2009	2772488
treatment of nasal polyps--medication or surgery and which technique.		2009	2772493
comparative dna reassociation kinetics of cranes.		2009	2775167
comparative dna reassociation kinetics of cranes.		2009	2775167
phagocytosis by guinea pig polymorphonuclear leukocytes of liposomes stabilized with polysaccharides.	hemolysate-loaded liposomes were prepared with their surface coated by polysaccharides, carboxymethylchitin, carboxymethylcellulose and carboxymethylchitosan. phagocytosis by guinea pig polymorphonuclear leukocytes of these coated liposomes was measured in view of electrostatic interactions between the cells and the liposomes. this view revealed to hold at least in quite an early stage of phagocytosis, but some specific interactions were assumed to exist between the cells and the liposomes. n-ac ...	1989	2775873
suppression of antibody responses to the acetylcholine receptor by natural antibodies.	some relationships between "natural" physiological autoreactivity and antibody responses against the acetylcholine receptor (achr) were investigated. collections of unselected monoclonal antibodies were derived from nonmanipulated newborn mice of susceptible (balb.b) and resistant (balb/c) mouse strains, and screened for reactivity with heterologous achr. five in 200 balb/c but none in 200 balb.b clones were found reactive. four of these anti-achr antibodies were analyzed for connectivity to nin ...	1989	2776827
virulence of vibrio vulnificus strains isolated from seafoods.	a study was carried out on the relation between virulence of v. vulnificus assessed by ld50 in mice and other markers. v. vulnificus strains isolated from seafoods had ld50 ranging from 10(3)-10(7) for mice. strains showing ld50 10(6) or less were generally haemolytic and settled after boiling. resistance to bactericidal action of serum and ability to take up congo red was shown by all the strains.	1989	2777343
stress fracture of the rib in an elite oarsman.	this paper documents an unusual case of a stress fracture of the ninth rib in an elite oarsman. a 25-year-old male presented with a 3-day history of right-sided chest pain aggravated by deep inspiration and movements simulating rowing. the athlete was treated initially as having a soft tissue injury; however, a technetium-99 bone scan confirmed the diagnosis. routine radiographs of the ribs were negative. the pain and symptoms were confined to the anatomical area of the fracture along the antero ...	2009	2777439
anomalous origin of right pulmonary artery from the ascending aorta.	anomalous origin of one pulmonary artery from the ascending aorta without associated intracardiac defects is a rare congenital malformation. about 60 anatomic and surgical descriptions have been reported in the literature. up to 1974, 22 of the 50 reported cases underwent surgical correction with a 40% mortality rate. the natural history without surgery is poor with a very high mortality during the first year of life. successful anatomic correction of anomalous origin of right pulmonary artery f ...	2009	2777879
human eosinophils express cd4 protein and bind human immunodeficiency virus 1 gp120.	the cd4 glycoprotein, expressed on leukocytes belonging to subsets of t lymphocytes and to cells of monocyte/macrophage lineage, participates in the functioning of t cells and serves as a receptor for hiv-1 and hiv-2. human eosinophils, a class of granulocytic leukocytes, have been found to express cd4. with anti-cd4 mabs cd4 was demonstrable on eosinophils from both normal and eosinophilic donors. eosinophils synthesized a 55-kd cd4 polypeptide immunoprecipitable with two anti-cd4 mabs. eosinop ...	1989	2783333
diagnostic and therapeutic technology assessment (datta). noninvasive electrical stimulation for nonunited bone fracture.		2009	2783614
the grading and prevalence of macular degeneration in chesapeake bay watermen.	a new grading scheme was developed to classify the fundus features of macular degeneration. this scheme identifies the earliest fundus changes associated with macular degeneration, as well as specific drusen characteristics felt to be associated with an increased risk of developing the exudative forms of this disease. agreement between two graders using this scheme indicated good interobserver reliability. using this scheme, fundus photographs of 777 participants were graded in a population-base ...	2009	2786408
[the results of an investigation of the various factors influencing the late patency ratio of coronary bypass grafting].	the purpose of this communication was to find out the factors influencing the late patency ratio of coronary artery bypass grafts of 42 patients in our institution. the following results were obtained: 1. the size of the measured diameters of coronary arteries and the graft flow rates were correlated well to the late patency ratio (p less than 0.05). 2. the regular physical exercise trainings were significantly important to keep patent grafts (p less than 0.01). 3. in blood serum studies, serum ...	2009	2786538
[single photon emission computed tomography by using n-isopropyl-p-[123i]-iodoamphetamine and 99mtc-hexamethyl propyleneamine oxime in a patient with herpes simplex encephalitis].	single photon emission computed tomographies (spects) by using n-isopropyl-p-[123i-imp]-iodo-amphetamine (123i-imp) and 99mtc-hexamethyl propyleneamine oxime (99mtc-hm-pao) were serially performed in a 70 yrs. old male with herpes simplex encephalitis (hse), and the chronological changes of accumulations were studied. accumulations of both 123i-imp and 99mtc-hm-pao increased initially, and then decreased with the stage of hse being advanced. the sequential appearance of the lesion in hse with 12 ...	2009	2786584
effect of vitamin d metabolites on calcitriol metabolism in experimental renal failure.	previous studies from our laboratory have demonstrated that metabolic clearance rate (mcr) of calcitriol is decreased in experimental renal failure. in this experiment, we examined the effects of calcitriol, 25-hydroxyvitamin d3 (25(oh)d3) and 24,25-dihydroxyvitamin d3 (24,25(oh)2d3) on the mcr of calcitriol in renal failure produced in rats by partial nephrectomy. the mcr of calcitriol in these rats with renal failure was significantly lower than in control rats with sham operations. plasma con ...	1989	2789310
the need for a more robust ozone air quality standard.	the present national ambient air quality standard for ozone has many statistical problems, including use of extreme values which have inherent large fluctuations, a compliance test that can gradually lower the target of the design value below the standard level, and inconsistencies between the number-of-exceedances criterion and the design value. the above problems can be avoided or minimized by using a more robust statistic, such as the 95th percentile, and applying a statistical compliance tes ...	2010	2795112
reversal of rejection-induced coronary vasculitis detected early after heart transplantation with increased immunosuppression.	four patients who underwent heart transplantation, in whom coronary obstruction was seen early after transplantation, are described. repeated acute rejection episodes were detected within the first 2 months in each patient. coronary obstruction or ischemia was shown through a combination of t1-201 isotopic study findings, evidence of vasculitis of a small coronary arteriole seen at endomyocardial biopsy, or coronary angiographic results. vigorous treatment for rejection (antithymocyte globulin a ...	2009	2795284
[neurosis or psychosis: a formal differentiation of practical interest].		2010	2797301
comparative study of the circadian rhythmicity in the urinary concentration of glycosaminoglycans in patients of calcium oxalate nephrolithiasis and in healthy adults.	glycosaminoglycans (gags) are potent inhibitors of calcium oxalate crystallisation and/or crystal aggregation. urinary concentration of gags has been shown to vary during 24 h; therefore, circadian rhythmicity in urinary concentration of gags was investigated in 33 healthy male adults in the age group of 20-40 years and in 27 male patients of a similar age group with calcium nephrolithiasis. three-hourly urine samples were collected for 24 h beginning from 00.00 h for estimation of urinary conce ...	2008	2800054
safety of intraaortic balloon counterpulsation in patients with acute myocardial infarction receiving streptokinase intravenously.		2009	2801563
[intestinal microbial ecology and its modulation under the influence of immunodepressants].	oral administration of immunodepressants such as imuran (purine analog) and batriden (gossypol derivative) for 3 months led to development of dysbacterioses in various sections of the rat gastrointestinal tract. the dysbacterioses differed in their levels and the pattern of the recovery process. as compared to batriden, imuran in a dose of 30 mg/kg body weight administered at the early observation periods (days 7, 14 and 30) induced more marked disorders in the intestine microecology. the imuran ...	1989	2802878
more on index of refraction.		2009	2805311
more on index of refraction.		2009	2805311
primary eruption of psoriasis in a donor site of a split-skin graft.		1997	2808809
[effect of glucocorticosteroid therapy on immunologic indicators in patients with sarcoidosis and idiopathic fibrosing alveolitis].	immunological findings were recorded in 22 patients with active sarcoidosis and 12 patients with idiopathic fibrosing alveolitis. in addition, the patients' endopulmonary cytograms were considered. immunological evidence involved the use of bronchoalveolar lavage, bronchoscopy, peripheral blood. administration of corticosteroid therapy resulted in alveolitis attenuation both in sarcoidosis and fibrosing alveolitis. common features of immune response of sarcoidosis and idiopathic fibrosing alveol ...	2009	2811240
etiology of nigerian adolescents' perception of their weight.		2009	2812993
etiology of nigerian adolescents' perception of their weight.		2009	2812993
role of carboxylesterase in soman, sarin and tabun poisoning in rats.	tocp (triorthocresyl phosphate) inhibits carboxylesterase (carbe) activity in rat plasma and liver and significantly increases soman, sarin and tabun toxicity. application of these agents after tocp caused strong additional inhibition of carbe and cholinesterases (che) in rat red blood cells, plasma, liver, brain, diaphragm and intercostal muscle. after phenobarbital pretreatment, which induced carbe activity in plasma and liver by 80% and that of plasma che by 33%, acute toxicity of soman and t ...	1989	2813290
physical exercise--an important factor for health. a position statement from the international federation of sports medicine.		2010	2814432
[5 years' infection statistics of an orthopedic clinic--pathogen spectrum, resistance status, therapeutic consequences].	in 1983 we started our statistical control for postoperative infections. the data are checked every half year. most common bacteria was staph. aureus followed by staph. epidermidis. we found a difference in the spectrum of bacteria between our postop. patients and the referred cases. a surgeon related control and our new operating theatres reduced the infection rate from 2.2% to 0.8%. for our total joint replacements we additionally used perioperative antibiotics. the change in the antibiotic fr ...	2009	2815951
the dermatopathologist and human immunodeficiency virus infection.		1989	2817921
a photographic study of enamel defects among south australian school children.	colour photographs were taken of the anterior teeth of 1757 consenting 8-9 year old primary school children in fluoridated and non-fluoridated areas of south australia. children with a lifelong exposure to fluoridated water were significantly more likely to have blemished permanent incisor teeth than the children who had never resided in a fluoridated area. children who resided in a non-fluoridated area but had taken fluoride supplements at some stage in their first five years had a prevalence o ...	2009	2818303
depolarization induced by injection of cyclic nucleotides into frog taste cell.	in order to identify the intracellular transmitter involved in the taste transduction process, cyclic nucleotides were iontophoretically injected into the frog taste cells while membrane potentials were recorded intracellularly. injection of either cyclic gmp or cyclic amp induced a depolarization response of about 5 mv in the taste cells, but injection of cl- had no effect. the rate of a repolarization after the depolarization elicited by cyclic gmp was larger than that after cyclic amp. the po ...	2009	2822117
depolarization induced by injection of cyclic nucleotides into frog taste cell.	in order to identify the intracellular transmitter involved in the taste transduction process, cyclic nucleotides were iontophoretically injected into the frog taste cells while membrane potentials were recorded intracellularly. injection of either cyclic gmp or cyclic amp induced a depolarization response of about 5 mv in the taste cells, but injection of cl- had no effect. the rate of a repolarization after the depolarization elicited by cyclic gmp was larger than that after cyclic amp. the po ...	2009	2822117
[mechanisms of hypergastrinemia after vagotomy].		1987	2824916
[mechanisms of hypergastrinemia after vagotomy].		1987	2824916
dopamine denervation of the nucleus accumbens induces a selective increase in the number of delta-opioid binding sites.	selective lesions of dopamine (da) neurons of the nucleus accumbens were made in rats by local injections of 6-hydroxydopamine (6-ohda). seven days after 6-ohda, the binding affinities and capacities at mu-, delta- and kappa-opioid binding sites were determined in the nucleus accumbens by selective labelling techniques. 6-ohda pretreatment caused a significant increase in the number of delta-opioid binding sites (+30%) while the number of mu-, kappa- and total sites was not modified. the affinit ...	1987	2825926
dopamine denervation of the nucleus accumbens induces a selective increase in the number of delta-opioid binding sites.	selective lesions of dopamine (da) neurons of the nucleus accumbens were made in rats by local injections of 6-hydroxydopamine (6-ohda). seven days after 6-ohda, the binding affinities and capacities at mu-, delta- and kappa-opioid binding sites were determined in the nucleus accumbens by selective labelling techniques. 6-ohda pretreatment caused a significant increase in the number of delta-opioid binding sites (+30%) while the number of mu-, kappa- and total sites was not modified. the affinit ...	1987	2825926
overlapping distributions of receptors for atrial natriuretic peptide and angiotensin ii visualized by in vitro autoradiography: morphological basis of physiological antagonism.	atrial natriuretic peptides exert actions on many key organs involved in blood pressure and water and electrolyte balance. many of these actions result in a physiological antagonism of angiotensin. to investigate the morphological basis of this interaction, we have mapped the distribution of receptors for atrial natriuretic peptide and angiotensin ii in a number of target organs, using 125i-labelled rat atrial natriuretic peptide (99-126) and 125i-labelled [sar1,ile8]angiotensin ii. in the kidne ...	1987	2825937
cytomegalovirus pneumonia.	cytomegalovirus (cmv) is a common virus that asymptomatically infects the majority of the population by early adulthood. after initial infection, the virus remains in a latent state in the host and can be reactivated under a variety of conditions. in contrast to the normal host, both primary and reactivated symptomatic cmv infections are common in certain immunocompromised patients including organ transplant recipients and patients with the acquired immunodeficiency syndrome (aids). one of the m ...	1987	2827281
mononuclear cell infiltration in central portions of human astrocytomas.	the mononuclear cell infiltration in the central portion of human low- and high-grade astrocytomas has been examined using monoclonal antibodies to cell surface differentiation antigens. there was no significant difference between the number of t cells, b cells, or macrophages. the okt8+ (suppressor/cytotoxic) t cell population was the major lymphocyte subset in the infiltrates. there was, however, indirect evidence for a proportion of the total okt8+ cells being natural killer cells. overall, t ...	1988	2830373
mononuclear cell infiltration in central portions of human astrocytomas.	the mononuclear cell infiltration in the central portion of human low- and high-grade astrocytomas has been examined using monoclonal antibodies to cell surface differentiation antigens. there was no significant difference between the number of t cells, b cells, or macrophages. the okt8+ (suppressor/cytotoxic) t cell population was the major lymphocyte subset in the infiltrates. there was, however, indirect evidence for a proportion of the total okt8+ cells being natural killer cells. overall, t ...	1988	2830373
cilia-associated respiratory (car) bacillus infection of obese mice.	cilia-associated respiratory (car) bacillus was identified in respiratory tract lesions of obese mice dying of chronic respiratory disease. neither mycoplasma pulmonis nor pathogenic bacteria were isolated from cultures of the lesions at necropsy, but there was serologic and histologic evidence of respiratory virus infection. cranial-ventral areas of lung were firm and demarcated from unaffected lung at gross examination, and representative tissue sank in water. microscopically, there was suppur ...	1988	2830699
cilia-associated respiratory (car) bacillus infection of obese mice.	cilia-associated respiratory (car) bacillus was identified in respiratory tract lesions of obese mice dying of chronic respiratory disease. neither mycoplasma pulmonis nor pathogenic bacteria were isolated from cultures of the lesions at necropsy, but there was serologic and histologic evidence of respiratory virus infection. cranial-ventral areas of lung were firm and demarcated from unaffected lung at gross examination, and representative tissue sank in water. microscopically, there was suppur ...	1988	2830699
cloning and expression of the vibrio cholerae neuraminidase gene nanh in escherichia coli.	a cosmid gene bank of vibrio cholerae 395, classical ogawa, was screened in escherichia coli hb101 for expression of the vibrio neuraminidase (nanase) gene nanh (n-acylneuraminate glycohydrolase). positive clones were identified by their ability to cleave the fluorogenic nanase substrate 2'-(4-methylumbelliferyl)-alpha-d-n-acetylneuraminic acid. seven nanase-positive clones were detected after screening 683 cosmid isolates with a rapid, qualitative plate assay method. the nanh gene was subcloned ...	1988	2832365
cloning and expression of the vibrio cholerae neuraminidase gene nanh in escherichia coli.	a cosmid gene bank of vibrio cholerae 395, classical ogawa, was screened in escherichia coli hb101 for expression of the vibrio neuraminidase (nanase) gene nanh (n-acylneuraminate glycohydrolase). positive clones were identified by their ability to cleave the fluorogenic nanase substrate 2'-(4-methylumbelliferyl)-alpha-d-n-acetylneuraminic acid. seven nanase-positive clones were detected after screening 683 cosmid isolates with a rapid, qualitative plate assay method. the nanh gene was subcloned ...	1988	2832365
propranolol enhances in vitro interleukin 2 receptor expression on human lymphocytes.	interleukin 2 receptor (il-2r) expression was assessed, using anti-tac monoclonal antibody, after incubation of human lymphocytes with the beta-adrenoceptor antagonist propranolol (pro). one-hour incubation of mononuclear cells (mnc) with pro resulted in an increase of tac positive cells. the greatest rise was observed with a pro concentration of 10(-6) m (29% ring-stained cells compared with 0% in the control group). cells cultured for 3 days with pro showed a lower proportion of tac positive c ...	1988	2836304
short-chain fatty acid transport in the intestine of a herbivorous teleost.	short-chain fatty acid (scfa) concentrations of intestinal contents from the herbivorous tilapia, oreochromis mossambicus, were analysed by gas and high-performance liquid chromatography. concentrations of acetate ranging from 3 to 18 mmol l-1 were found along the full length of the intestinal tract, as were trace amounts of propionate. characteristics of [3h]acetate transport by the intestinal brush-border membrane were analysed in isolated brush-border membrane vesicles (bbmv). influx of [3h]a ...	2009	2836545
short-chain fatty acid transport in the intestine of a herbivorous teleost.	short-chain fatty acid (scfa) concentrations of intestinal contents from the herbivorous tilapia, oreochromis mossambicus, were analysed by gas and high-performance liquid chromatography. concentrations of acetate ranging from 3 to 18 mmol l-1 were found along the full length of the intestinal tract, as were trace amounts of propionate. characteristics of [3h]acetate transport by the intestinal brush-border membrane were analysed in isolated brush-border membrane vesicles (bbmv). influx of [3h]a ...	2009	2836545
[fatal septicemia of vibrio vulnificus in a patient with chronic hepatitis].		1987	2836645
mechanism of the epsp synthase catalyzed reaction: evidence for the lack of a covalent carboxyvinyl intermediate in catalysis.	in order to detect covalent reaction intermediates in the 5-enolpyruvylshikimate-3-phosphate (epsp) synthase reaction, we have investigated the interaction of epsp synthase with the reaction product epsp. an exchange of epsp-methylene protons could be demonstrated by incubating epsps with epsp in d2o. since trace amounts of contaminating pi would lead to reversal of epsps reaction and hence methylene proton exchange, we added pyruvate kinase, adp, mg++ and k+. under these conditions, any contami ...	1988	2838023
evaluation of guar biscuits for use in the management of diabetes: tests of physiological effects and palatability in non-diabetic volunteers.	a guar-shortbread biscuit has been successfully developed and tested for possible use in the dietary management of diabetes. a dose-response study was undertaken to estimate the amount of guar gum needed in the biscuit recipe to reduce postprandial glycaemia and insulinaemia. a control biscuit and three types of guar biscuit corresponding to a low, medium and high dose of guar (2.9, 6.0 and 9.1 g of guar respectively) were given to 8 non-diabetic subjects, and blood glucose and plasma insulin le ...	2010	2840279
thiol peroxyl radical formation from the reaction of cysteine thiyl radical with molecular oxygen: an esr investigation.	using electron spin resonance (esr) spectroscopy, we have identified the cysteine thiol peroxyl radical (cyssoo.) at low temperatures in two aqueous glasses. this radical shows a typical peroxyl radical esr spectrum, but unlike carbon-based peroxyl radicals has a violet color (lambda max = 540 nm) and forms a new radical showing a singlet esr spectrum when photobleached with visible light. the cysteine peroxyl radical reacts to form the cysteine sulfinyl radical (cysso.) in the glass which allow ...	2010	2843184
specificity of synapse formation in the cockroach.	the synaptic connection between the filiform hair sensory neurons (fhsns) and the giant interneurons (gis) in the terminal abdominal ganglion of the first-instar cockroach periplaneta americana has been used as a model system for investigating the mechanism of synaptic specificity. electrophysiological and electron microscopical techniques were used to determine the normal patterns of connectivity between fhsns and gis. it was found that, even during synaptogenesis, no incorrect synapses were fo ...	2009	2847212
specificity of synapse formation in the cockroach.	the synaptic connection between the filiform hair sensory neurons (fhsns) and the giant interneurons (gis) in the terminal abdominal ganglion of the first-instar cockroach periplaneta americana has been used as a model system for investigating the mechanism of synaptic specificity. electrophysiological and electron microscopical techniques were used to determine the normal patterns of connectivity between fhsns and gis. it was found that, even during synaptogenesis, no incorrect synapses were fo ...	2009	2847212
chemotaxis in eukaryotic cells: a focus on leukocytes and dictyostelium.		2010	2848555
transcriptional regulation of the gene encoding the major surfactant protein (sp-a) in rabbit fetal lung.	the expression of the major protein of rabbit pulmonary surfactant (sp-a), a glycoprotein of mr congruent to 29,000-36,000, is regulated during development and by hormones. in the present study, utilizing a cdna insert complementary to mrna coding for sp-a and nuclear transcription elongation assays, we have investigated the developmental and hormonal regulation of transcription of the sp-a gene in rabbit fetal lung tissue. the relative rates of transcription of sp-a mrna increased as a function ...	1988	2848814
[the entero-insular axis: the new incretin candidate glucagon-like peptide-1(7-36)amide (glp-1(7-36))amide].	the functional connection between the gut and pancreatic islets is described by the term "enteroinsular axis". a humoral factor of the gut that might enhance the glucose-induced secretion of insulin is named "incretin". for many years glucose-dependent insulin-releasing polypeptide (gip) was the strongest incretin candidate. however, recent evidence suggests that glucagon-like peptide-1(7-36)amide represents a more potent physiological incretin. the sequence of glp-1 is identical in various mamm ...	1988	2849249
factors influencing the severity of escherichia coli and avian adenovirus group ii infections in chickens.	chickens from lines selectively bred for either a high (hh) or low (ll) antibody response to sheep erythrocytes were challenged intravenously with avian adenovirus group ii (aa). spleen size was determined 6 days later. in some experiments the responses of chickens to aa and escherichia coli infections were compared. the level of corticosterone in the feed (15 mg/kg) which resulted in the lowest incidence of pericarditis in response to e. coli resulted in the greatest incidence of large spleens ...	1988	2849405
suppression of sv40-promoted gene expression by differentiation of preadipose cells.	when a plasmid bearing the chloramphenicol acetyltransferase (cat) gene under the control of an sv40 early promoter is introduced into preadipose or adipose cells of line 3t3-f442a, the promoter directs high levels of transient expression of cat. however, when the plasmid is introduced into preadipose cells and the cells are then allowed to differentiate into adipose cells, the expression of the cat gene is suppressed. in this process, the plasmid is not changed detectably in amount, topology, o ...	1988	2849579
[changes in the cyclic nucleotide system of t-lymphocytes in experimental tuberculosis in animals].		1988	2851783
a murine monoclonal antibody raised against human non-small cell carcinoma of the lung.	murine monoclonal antibodies (mabs) reactive with human non-small cell carcinoma of the lung (nsccl) were produced following immunization with a membrane preparation of calu-3, a human adenocarcinoma of the lung cell line grown in nude mice. positive hybrids unreactive with normal liver membranes and human peripheral white blood cells were selected for further testing. one mab (rs5-4h6) recognized an antigen expressed in a variety of lung and other carcinoma cell lines as detected by flow cytome ...	1988	2853133
survival of smallpox virus.		1985	2857360
benzodiazepines enhance the muscimol-dependent activation of phospholipase a2 in glioma c6 cells.	glioma c6 cells were incubated with [14c]arachidonate to label membrane phospholipids. muscimol, a selective gamma-aminobutyric acid a receptor agonist, but not (-)-baclofen, a selective gamma-aminobutyric acid b receptor agonist, stimulates [14c]arachidonate release from c6 cells as a result of hydrolysis of a small pool of phosphatidylcholine and phosphatidylethanolamine by phospholipase a2. this release is facilitated by diazepam and a number of other benzodiazepines such as flunitrazepam, me ...	1985	2857784
immunochemical recognition of oxytocin by antiserum to l-prolyl-leucyl-glycine amide.	antisera were raised in rabbits against pro-leu-gly-nh2 (plg)-bovine thyroglobulin conjugates. specificity of the antisera towards oxytocin was evaluated by a radioimmunoassay as well as by immunohistochemical procedures on hypothalamic tissue and hormone bound to sepharose beads. it was concluded that immunization with plg can raise antisera that are specific to oxytocin.	1985	2859563
lymphatic transport of sodium cefoxitin in the presence of sodium 5-methoxysalicylate after injection into rat rectal connective tissue, femoral muscle and femoral vein.	lymphatic uptake of sodium cefoxitin after injection into rectal connective tissue was greater than after injection into the femoral muscle of rats. coadministration with sodium 5-methoxysalicylate enhanced lymphatic drug uptake at both sites. this enhancement may be an indirect result of 5-methoxysalicylate's suppression of vascular permeation of the cefoxitin. an adjuvant-induced increase in lymphatic fluid flow may also be partially involved in the enhancement of cefoxitin lymphatic transport ...	1985	2863362
[physiological and pharmacologic studies of the adrenal medulla by the measurement of plasma catecholamine levels].	the new techniques for the assay of the plasma catecholamines: noradrenaline, dopamine and, most importantly, adrenaline, because of their sensitivity and precision, have provided new information about the physiology and the pharmacology of the adrenal medulla in animals and in man. the most effective of these new techniques are the radioenzymatic techniques. the activation of the adrenal medulla in the dog or the rat appears to be frequency-dependent by maintaining a fixed concentration ratio i ...	1985	2863423
hypotensive effects after topical and intra-arterial administration of alpha-adrenergic agonists in isolated perfused rabbit eyes.	the influence of nonselective and selective alpha-adrenergic agonists on intraocular pressure (iop) was studied in isolated arterially perfused rabbit eyes. drugs were given intra-arterially or topically. with either route of administration, no initial hypertensive phase was observed after l-epinephrine, l-norepinephrine, l-phenylephrine (alpha 1), or methoxamine (alpha 1), but there was an immediate ocular hypotensive effect. the alpha 2-agonist b-ht 920 caused a nonsignificant 1 mm hg fall in ...	1985	2866480
neural and pavlovian influences on immunity.	the traditional view that the nervous and immune systems are functionally independent (aside from general stress effects and autoimmune disorders of the nervous system) is being challenged by a new view that the nervous system regulates the activity of the immune system. if this is true, it should be possible to change the activity of the immune system by means of pavlovian conditioning, just as it is possible to condition other physiological events influenced by the autonomic nervous system or ...	1985	2866484
synthesis and quantitative structure-activity relationships of antiallergic 2-hydroxy-n-1h-tetrazol-5-ylbenzamides and n-(2-hydroxyphenyl)-1h-tetrazole-5-carboxamides.	the synthesis and antiallergic activity of a series of 2-hydroxy-n-1h-tetrazol-5-ylbenzamides and isomeric n-(2-hydroxyphenyl)-1h-tetrazole-5-carboxamides is described. a relationship between structure and intravenous antiallergic activity in the rat passive cutaneous anaphylaxis (pca) test has been established using a hansch/free-wilson model and used to direct studies toward potent derivatives. the contribution of physicochemical properties to activity is discussed. one member of this series, ...	1986	2870188
in-vivo fertilised ovum donated successfully to a woman without ovaries.		2005	2870261
[pharmacokinetic interaction of drugs with cardiac glycosides; which are clinically important?].		2006	2870436
accessory adrenal: an incidental finding during orchiopexy.		2006	2870456
pain, prostaglandins, and food lipids. influences of dietary polyunsaturated fatty acids on eicosanoid synthesis and effects.		2007	2870709
report of a wound infection caused by vibrio parahaemolyticus and vibrio vulnificus.	the present case describes a foot wound caused by a clam shell from which both vibrio parahaemolyticus and vibrio vulnificus were recovered. although extraintestinal infections associated with vibrio parahaemolyticus have been reported previously, the simultaneous isolation of two marine vibrios from our case suggests that these organisms may coexist in mixed infections from a common source.	1986	2875824
[arterial hypertension in the aged].		2010	2876472
effects of somatostatin and sms 201-995 on carbohydrate metabolism in normal man.	growth hormone (gh) is important in diabetes in view of its anti-insulin actions and its relation to the long-term complications of the disease. the suppression of gh secretion in diabetics has theoretical and possible therapeutic interest. native somatostatin has multiple actions, including inhibition of the secretion of insulin, glucagon, thyroid-stimulating hormone (tsh), and various gut hormones. it also has inhibitory effects on gastrointestinal motility, exocrine secretion, nutrient absorp ...	1986	2876501
directives, methods and suggestions for anti-ulcer drug therapy.		2010	2876535
adenosine receptors mediate pigment dispersion in leucophores of the medaka, oryzias latipes.	using the medaka, oryzias latipes (orange-red variety), the mechanisms of action on leucophores of adenosine and adenine nucleotides, including cyclic amp, were studied. all these substances were found to be very effective in dispersing leucosomes. their pigment-dispersing action was antagonized by methylxanthines. these substances did not aggregate leucosomes. it was concluded that leucophores possess specific binding sites for adenosine, i.e. adenosine receptors, on the cell membrane, which me ...	2010	2877798
1,4-dithiothreitol-induced changes in histamine h1-agonist efficacy and affinity in the longitudinal smooth muscle of guinea-pig ileum.	the effect of 1,4-dithiothreitol (dtt) on histamine h1-receptor agonist affinity and efficacy has been investigated in longitudinal muscle strips of guinea-pig ileum. exposure of ileal smooth muscle to dtt significantly increased the maximal responses to the partial agonists skf71473 and de-2pea, indicative of an increase in agonist efficacy. this effect was paralleled by a small decrease in ec50 values. in contrast, dtt produced a parallel displacement of the concentration-response curve to the ...	1987	2880626
glutathione metabolizing enzyme activities in human thyroid.	glutathione peroxidases, glutathione transferase, glutathione reductase and gamma-glutamyl transpeptidase activities were analyzed in human thyroid tissues obtained from 17 patients undergoing resectional surgery because of a malignancy. it was deduced, from measurements of glutathione peroxidase activity with both h202 and cumene hydroperoxide, that thyroid contains only the selenium enzyme. the absence of selenium independent glutathione peroxidase activity in thyroid was confirmed with gel fi ...	1987	2883074
congenital adrenal hyperplasia.		2010	2887945
absence of age-related changes in the binding of the beta adrenergic antagonist 125i-iodohydroxybenzylpindolol in rat heart.	the effect of age on the density and the affinity of beta adrenergic receptors was determined in the hearts of fischer 344 rats at three ages, 6, 12, and 24 months old. the binding of the beta adrenergic antagonist 125i-iodohydroxybenzylpindolol (ihyp), was used to quantitate and characterize cardiac beta adrenergic receptors. the maximal number of binding sites (bmax = f moles/mg of protein) were 26.3 +/- 2.5, 25.4 +/- 0.99, and 24.5 +/- 2.4 and the dissociation constants (kd = nm) were 0.166 + ...	1987	2888126
chlamydia trachomatis in antenatal clinics.		1987	2889053
[h2-antihistaminics. 35. synthesis and h2-antagonistic action of imidazolylmethylthioalkyl-substituted 1,2,4-triazoles].		1987	2889442
a unique t-cell line derived from an htlv-1-negative adult t-cell leukemia patient.	a unique t-cell line, designated atl-5t, was established from lymphoma cells in pericardial effusion of an adult t-cell leukemia (atl) patient not carrying htlv-1 provirus. the cell line is okt4 and/or leu3a+ and okt8 and/or leu2a+, but interleukin 2 receptor (il2r)- and htlv-1 provirus genome negative, and has cytogenetically abnormal karyotypes. the cell line contains rearranged t-cell receptor beta-chain gene, which was identical in rearrangement pattern to the t-cell receptor beta-chain gene ...	1987	2890613
diabetogenic action of calcitonin in acute experiment in healthy humans.		2010	2894137
isolated duodenal tamponade for treatment of bleeding duodenal ulcer.		2010	2895833
inhibition of nucleic acid synthesis in p-388 lymphocytic leukemia cells in culture by sesquiterpene lactones.	helenalin and bis (helenalinyl) malonate, sesquiterpene lactones, were shown to be cytotoxic against the growth of p-388 lymphocytic leukemia cells in culture. dna and protein synthesis were reduced by these agents preferentially, with rna synthesis being affected only marginally. this study focused on the identification of the enzyme target(s) responsible for the inhibition of dna synthesis by the sesquiterpene lactones. purine synthesis was strongly inhibited at the imp dehydrogenase step. sup ...	2010	2895992
importance of pulmonary blood volume and aortic blood pressure in regulation of left ventricular function.		1988	2900297
inhibitory effect of glycyrrhetinic acid derivatives on arachidonic acid-induced mouse ear oedema.	the inhibitory effects of glycyrrhetinic acid and its derivatives were examined on arachidonic acid (aa)-induced ear oedema in mice. of the compounds, dihemiphthalate derivatives of 18 beta-olean-12-ene-3 beta, 30-diol (iid, iid'), 18 beta-olean-9(11)12-diene-3 beta, 30-diol (iiia, iiia') and olean-11, 13(18)-diene-3 beta, 30-diol (iva, iva') showed a strong inhibition of ear oedema on both tropical (id50, 1.9, 2.8 and 1.7 mg/ear, respectively) and oral (id50, 90, 130 and 88 mg kg-1, respectivel ...	1988	2900308