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dry matter and digesta particle size gradients along the goat digestive tract on grass and browse diets.physical properties of the digesta vary along the ruminant digestive tract. they also vary within the forestomach, leading to varying degrees of rumen contents stratification in 'moose-type' (browsing) and 'cattle-type' (intermediate and grazing) ruminants. we investigated the dry matter concentration (dm) and the mean digesta particle size (mps) within the forestomach and along the digestive tract in 10 goats fed grass hay or dried browse after a standardized 12-h fast, euthanasia and freezing ...201727016403
range expansion of moose in arctic alaska linked to warming and increased shrub habitat.twentieth century warming has increased vegetation productivity and shrub cover across northern tundra and treeline regions, but effects on terrestrial wildlife have not been demonstrated on a comparable scale. during this period, alaskan moose (alces alces gigas) extended their range from the boreal forest into tundra riparian shrub habitat; similar extensions have been observed in canada (a. a. andersoni) and eurasia (a. a. alces). northern moose distribution is thought to be limited by forage ...201627074023
does predation influence the seasonal and diel timing of moose calving in central ontario, canada?birth synchrony is well documented among ungulates and is hypothesised to maximize neonate survival, either by minimizing the risk of predation through predator swamping or by synchronising birthing with increased seasonal food availability. we used encapsulated vaginal implant transmitters to locate and capture neonatal moose calves and document the seasonal and diel timing of parturition in two adjacent study areas with different predation pressure in central ontario, canada. we tested the hyp ...201627082234
morphological and molecular characterization of sarcocystis taeniata and sarcocystis pilosa n. sp. from the sika deer (cervus nippon) in lithuania.the diaphragm muscles of eight sika deer (cervus nippon) bred in lithuania were examined for sarcocystis cysts. two sarcocystis species, sarcocystis taeniata, which were previously reported in canadian moose (alces alces) and argentinean red deer (cervus elaphus), and sarcocystis pilosa n. sp. were described using light microscopy (lm), transmission electron microscopy (tem), 18s ribosomal dna (rdna), and subunit i of cytochrome c oxidase (cox1) sequences analysis. by lm, cysts of s. taeniata we ...201627086872
risk of symptomatic intracerebral hemorrhage after intravenous thrombolysis in patients with acute ischemic stroke and high cerebral microbleed burden: a meta-analysis.cerebral microbleeds (cmbs) have been established as an independent predictor of cerebral bleeding. there are contradictory data regarding the potential association of cmb burden with the risk of symptomatic intracerebral hemorrhage (sich) in patients with acute ischemic stroke (ais) treated with intravenous thrombolysis (ivt).201627088650
association between gnb3 c.825c > t polymorphism and the risk of overweight and obesity: a meta-analysis.the association between g protein β-polypeptide 3 gene (gnb3) c.825c > t polymorphism (rs5443) and the risk of overweight/obesity has been investigated in many published studies, but the results were conflicting and inconclusive. a meta-analysis was performed to make a more accurate assessment of the relationship.201627114919
alternative prey use affects helminth parasite infections in grey wolves.predators affect prey populations not only through direct predation, but also by acting as definitive hosts for their parasites and completing parasite life cycles. understanding the affects of parasitism on prey population dynamics requires knowing how their predators' parasite community is affected by diet and prey availability. ungulates, such as moose (alces americanus) and white-tailed deer (odocoileus virginianus), are often important prey for wolves (canis lupus), but wolves also consume ...201627155132
maternal psychosocial consequences of twins and multiple births following assisted and natural conception: a meta-analysis.the aim of this meta-analysis is to provide new evidence on the effects on maternal health of multiple births due to assisted reproductive technology (art). a bibliographic search was undertaken using pubmed, psycinfo, cinahl and science direct. data extraction was completed using cochrane review recommendations, and the review was performed following prisma and moose guidelines. meta-analytic data were analysed using random effects models. eight papers (2993 mothers) were included. mothers of a ...201627156004
modelling (137)cs concentrations in moose (1986-2012) from areas highly contaminated by the chernobyl fallout.data from long term annual monitoring of (137)cs concentrations in harvested moose (alces alces) were empirically modelled by applying multivariate data analysis that is able to from relatively raw datasets show how the many various impact variables are related (principal component analysis, pca). in the later stage regression modelling (partial least squares, pls) was applied to analyse which environmental and physiological factors were significant (i.e. of predictive value) based on the measur ...201627162195
effects of liver transplantation on endocrine function: a systematic review.patients with chronic liver disease (cld) often experience secondary endocrine dysfunction. therefore, because the liver plays a major role in endocrine function, liver transplantation (lt) may also be beneficial for the restoration of hormonal regulation. this systematic review collects and interprets the available literature on the effect of lt on endocrine and sexual function in adult patients. a systematic review was conducted by searching pubmed (including medline) and embase for studies pu ...201627163168
endoscopic resection of sinonasal malignancy: a systematic review and meta-analysis.the use of endoscopic approaches for sinonasal malignancy resection has increased, but survival data are limited secondary to disease rarity and new surgical technique. here we present a systematic review and meta-analysis of endoscopic endonasal resection of sinonasal malignancy.201627165676
a systematic review of the burden of vaccine preventable pneumococcal disease in uk adults.invasive pneumococcal disease (ipd) and pneumococcal pneumonia are common and carry a significant morbidity and mortality. current strategies to prevent pneumococcal disease are under review in the united kingdom (uk). we conducted a systematic review to evaluate the burden of vaccine type adult pneumococcal disease specifically in the uk.201627169895
harvest-induced phenotypic selection in an island population of moose, alces alces.empirical evidence strongly indicates that human exploitation has frequently led to rapid evolutionary changes in wild populations, yet the mechanisms involved are often poorly understood. here, we applied a recently developed demographic framework for analyzing selection to data from a 20-year study of a wild population of moose, alces alces. in this population, a genetic pedigree has been established all the way back to founders. we demonstrate harvest-induced directional selection for delayed ...201627174031
diagnosis of severe fetomaternal hemorrhage with fetal cerebral doppler: case series and systematic review.to analyze the role of middle cerebral artery (mca) peak systolic velocity (psv) in the prediction of severe fetomaternal hemorrhage (fmh) and to compare it with standard biophysical assessment.201727174184
the first detection of species of babesia starcovici, 1893 in moose, alces alces (linnaeus), in norway.babesiosis is an emerging zoonotic disease and various wildlife species are reservoir hosts for zoonotic species of babesia starcovici, 1893. the objective of the present study was to investigate the presence and prevalence of babesia spp. in moose alces alces (linnaeus) in two regions of norway. a total of 99 spleen samples were collected from animals of various ages from an area with the occurrence of the tick ixodes ricinus (linnaeus, 1758), and from an area where the ticks are known to be ab ...201627188749
description and life-cycle of taenia lynciscapreoli sp. n. (cestoda, cyclophyllidea).a new species of tapeworm, taenia lynciscapreoli sp. n. (cestoda, cyclophyllidea), is described from the eurasian lynx (lynx lynx), the main definitive host, and the roe deer (capreolus capreolus and capreolus pygargus), the main intermediate hosts, from finland and russia (siberia and the russian far east). the new species was found once also in the wolf (canis lupus) and the eurasian elk/moose (alces alces), representing accidental definitive and intermediate hosts, respectively. the conspecif ...201627199592
dietary magnesium and copper affect survival time and neuroinflammation in chronic wasting disease.chronic wasting disease (cwd), the only known wildlife prion disease, affects deer, elk and moose. the disease is an ongoing and expanding problem in both wild and captive north american cervid populations and is difficult to control in part due to the extreme environmental persistence of prions, which can transmit disease years after initial contamination. the role of exogenous factors in cwd transmission and progression is largely unexplored. in an effort to understand the influence of environ ...201627216881
cadmium and other elements in tissues from four ungulate species from the mackenzie mountain region of the northwest territories, canada.tissue samples from four ungulate species from the south mackenzie mountain region of the northwest territories (nt), canada, were analysed for stable and radioactive elements and (15)n and (13)c stable isotopes. elevated cd concentrations in moose (alces americanus) kidney have been observed in the region and are a health care concern for consumers of traditional foods. this study examined the factors associated with, and potential renal effects from, the accumulation of cadmium, and interactio ...201627240258
lungworm (nematoda: protostrongylidae) infection in wild and domestic ruminants from małopolska region of poland.the conducted study has focused on domestic, as well as wild ruminant species. the post mortem examination was carried out on 68 animals, including three wild species: roe deer (capreolus capreolus) (25 indyviduals), red deer (cervus elaphus) (6), fallow deer (dama dama) (5) and two domestic: sheep (ovis aries) (14) and cattle (bos taurus) (18). some of the species have also been investigated in the field by the coproscopical analyses. the faecal samples from roe deer (27), fallow deer (20), red ...201627262959
mosquitoes in moose country: a mosquito survey of northern minnesota.an adult mosquito survey was conducted at 12 sites using carbon dioxide traps in northern minnesota throughout the summer of 2012. specimens were counted, identified to species, sorted into pools, and tested for eastern equine encephalitis (eeev) and west nile virus (wnv). our findings extend the known range of culiseta melanura, anopheles barberi, and an. quadrimaculatus and document the presence and abundance of 27 other mosquito taxa in the region. none of the pools tested positive for eeev o ...201627280346
effect of exercise training on sleep apnea: a systematic review and meta-analysis.obstructive sleep apnea (osa) is difficult to manage for those who are intolerant or noncompliant with standard facial mask treatment options. current treatment options do not address the underlying cause of osa. exercise as a treatment option has been found to improve osa indices.201627296826
prognostic role of mucin antigen muc4 for cholangiocarcinoma: a meta-analysis.surgery carries the best hope for cure in the treatment of cholangiocarcinoma (cc), whereas surgical outcome is not fully satisfactory. bio-molecular markers have been used to improve tumor staging and prognosis prediction. mucin antigen muc4 (muc4) has been implicated as a marker for poor survival in various tumors. however, prognostic significance of muc4 for patients with cc remains undefined. the aim of the present meta-analysis was to investigate the association between muc4 expression and ...201627305093
association between antioxidant intake/status and obesity: a systematic review of observational studies.the global prevalence of obesity has doubled in recent decades. compelling evidences indicated that obesity was associated with lower concentrations of specific antioxidants which may play a role in the development of obesity-related diseases such as cardiovascular disease. the present review aimed to synthesize the evidence from studies on the association between obesity and antioxidant micronutrients in a systematic manner. data bases including medline, science direct, and cochrane were search ...201727334437
large herbivores surf waves of green-up during spring.the green wave hypothesis (gwh) states that migrating animals should track or 'surf' high-quality forage at the leading edge of spring green-up. to index such high-quality forage, recent work proposed the instantaneous rate of green-up (irg), i.e. rate of change in the normalized difference vegetation index over time. despite this important advancement, no study has tested the assumption that herbivores select habitat patches at peak irg. we evaluated this assumption using step selection functio ...201627335416
xrcc1 and ogg1 gene polymorphisms and breast cancer: a systematic review of literature.known polymorphisms of dna repair genes can be associated with the risk of many types of cancer. there is no consensus regarding association between xrcc1 and ogg1 with breast cancer (bc).201627366307
therapeutic approach to igg4-related disease: a systematic review.to review the reported evidence on the therapeutic management of igg4-related disease (igg4-rd) in clinical practice.a systematic search of the literature was conducted. the primary outcome measured was the rate of efficacy of first-line therapeutic approaches. secondary outcomes measured included the rate of disease relapse, the outcome of untreated patients, the rate of patients without drug therapy at the end of follow-up, the rate of side effects, and mortality. the moose, ahrq, strobe, and ...201627368010
first evidence of established populations of the taiga tick ixodes persulcatus (acari: ixodidae) in sweden.the tick species ixodes ricinus and i. persulcatus are of exceptional medical importance in the western and eastern parts, respectively, of the palaearctic region. in russia and finland the range of i. persulcatus has recently increased. in finland the first records of i. persulcatus are from 2004. the apparent expansion of its range in finland prompted us to investigate if i. persulcatus also occurs in sweden.201627370406
guidelines for reporting medical research: a critical appraisal.as a response to a low quality of reporting of medical research, guidelines for several different types of study design have been developed to secure accurate reporting and transparency for reviewers and readers from the scientific community. herein, we review and discuss the six most widely accepted and used guidelines: prisma, consort, strobe, moose, stard, and spirit. it is concluded that the implementation of these guidelines has led to only a moderate improvement in the quality of the repor ...201627382637
ungulate browsers promote herbaceous layer diversity in logged temperate forests.ungulates are leading drivers of plant communities worldwide, with impacts linked to animal density, disturbance and vegetation structure, and site productivity. many ecosystems have more than one ungulate species; however, few studies have specifically examined the combined effects of two or more species on plant communities. we examined the extent to which two ungulate browsers (moose [alces americanus]) and white-tailed deer [odocoileus virginianus]) have additive (compounding) or compensator ...201627386099
prognostic significance of neutrophil-to-lymphocyte ratio in colorectal liver metastasis: a systematic review and meta-analysis.inflammation is deemed to play critical roles in tumor progression and metastasis, and an increased neutrophil-lymphocyte ratio (nlr) has been reported to correlate with poor survivals in various malignancies. however, association between nlr elevation and survival outcome in patients with colorectal liver metastasis (crlm) remains controversial. the aim of this study was to investigate the prognostic significance of elevated nlr in crlm.201627427969
correction: range expansion of moose in arctic alaska linked to warming and increased shrub habitat.[this corrects the article doi: 10.1371/journal.pone.0152636.].201727442025
substrate-driven convergence of the microbial community in lignocellulose-amended enrichments of gut microflora from the canadian beaver (castor canadensis) and north american moose (alces americanus).strategic enrichment of microcosms derived from wood foragers can facilitate the discovery of key microbes that produce enzymes for the bioconversion of plant fiber (i.e., lignocellulose) into valuable chemicals and energy. in this study, lignocellulose-degrading microorganisms from the digestive systems of canadian beaver (castor canadensis) and north american moose (alces americanus) were enriched under methanogenic conditions for over 3 years using various wood-derived substrates, including ( ...201627446004
migraine and breast cancer risk: a meta-analysis of observational studies based on moose compliant.it has long been speculated that migraine may contribute to an increased risk of breast cancer; however, results from previous studies have been inconclusive. to definitively interrogate this issue, we performed a meta-analysis to assess the correlation between these 2 diseases.medline and pubmed were searched to identify relevant studies that had been published until october 2015. based on a random effects model, relative risk (rr) and the corresponding 95% confidence interval (ci) were used to ...201627472675
physical activity and alzheimer disease: a protective association.to explore whether being physically active can decrease alzheimer disease (ad) risk.201627492909
fatty acid composition of birds and game hunted by the eastern james bay cree people of québec.indigenous peoples have traditionally relied on foods hunted and gathered from their immediate environment. the eastern james bay cree people consume wild game and birds, and these are believed to provide health as well as cultural benefits.201627495903
identification of the pregnancy-associated glycoprotein family (pags) and some aspects of placenta development in the european moose (alces alces l.).this study describes the identification and a broad-based characterization of the pregnancy-associated glycoprotein (pag) genes expressed in the synepitheliochorial placenta of the alces alces (aa; n = 51). we used: (1) both size measurements (cm) of various aa embryos/fetuses (crown-rump length) and placentomes (plcs); (2) pcr, southern and sequencing; (3) western-blot for total placental glycoproteins; (4) deglycosylation of total cotyledonary proteins; and (5) double heterologous ihc for cell ...201627501873
postglacial viability and colonization in north america's ice-free corridor.during the last glacial maximum, continental ice sheets isolated beringia (northeast siberia and northwest north america) from unglaciated north america. by around 15 to 14 thousand calibrated radiocarbon years before present (cal. kyr bp), glacial retreat opened an approximately 1,500-km-long corridor between the ice sheets. it remains unclear when plants and animals colonized this corridor and it became biologically viable for human migration. we obtained radiocarbon dates, pollen, macrofossil ...201627509852
association between mesothelin expression and survival outcomes in patients with triple-negative breast cancer: a protocol for a systematic review.mesothelin is a membrane-bound glycoprotein. although the biologic function of mesothelin is not very clear, researchers have found that it plays a role in the survival, proliferation, and migration of tumor cells. identified as a tumor-associated biomarker, mesothelin is more often overexpressed in triple-negative breast cancer (tnbc) than in common luminal breast tumor subtype or normal tissues. the objective of this review is to determine the association between the expression of mesothelin a ...201627514374
epidemiology of the lymphatic-dwelling filarioid nematode rumenfilaria andersoni in free-ranging moose (alces alces) and other cervids of north america.moose (alces alces) are a culturally and economically valued species in minnesota, where the northeast population has decreased by 60 % since 2006. the cause of the decline is currently unclear; however, parasites, predation, and climate change have all been implicated. nematode parasites are important pathogens in north american moose, potentially causing severe disease and mortality. recent spread of rumenfilaria andersoni, a filarioid nematode of moose, has been documented in finnish cervids; ...201627519789
reproductive behaviors and risk of developing breast cancer according to tumor subtype: a systematic review and meta-analysis of epidemiological studies.breast cancer is composed of distinct subtypes defined mainly based on the expression of hormone receptors (hr) and her2. for years, reproductive factors were shown to impact breast cancer risk but it is unclear whether this differs according to tumor subtype. in this meta-analysis we evaluated the association between parity, age at first birth, breastfeeding and the risk of developing breast cancer according to tumor subtype.201627529149
significantly higher peripheral fibroblast growth factor-2 levels in patients with major depressive disorder: a preliminary meta-analysis under moose guidelines.in vivo and in vitro studies demonstrate the important roles of fibroblast growth factor (fgf) and fgf receptors (fgfrs) in neural survival, neurogenesis, oxidative stress, and emotional behavior. however, evidence on the role of fgf and fgfr in the pathophysiology of major depressive disorder (mdd) remains limited and inconclusive.201627537581
publication bias and nonreporting found in majority of systematic reviews and meta-analyses in anesthesiology journals.systematic reviews and meta-analyses are used by clinicians to derive treatment guidelines and make resource allocation decisions in anesthesiology. one cause for concern with such reviews is the possibility that results from unpublished trials are not represented in the review findings or data synthesis. this problem, known as publication bias, results when studies reporting statistically nonsignificant findings are left unpublished and, therefore, not included in meta-analyses when estimating ...201627537925
case fatality of adult tetanus in africa: systematic review and meta-analysis.tetanus is a continued public health neuroinfectious burden in africa; it accounts for significant proportion of lengthy intensive care unit (icu) and hospital admissions.201627538652
what effect does transition have on health and well-being in young people with intellectual disabilities? a systematic review.transition to adulthood might be a risk period for poor health in people with intellectual disabilities. however, the present authors could find no synthesis of evidence on health and well-being outcomes during transition in this population. this review aimed to answer this question.201627554952
caribou consumption in northern canadian communities.chronic wasting disease (cwd) is a transmissible spongiform encephalopathy (tse) found in both farmed and wild deer, elk, and moose in the united states and canada. surveillance efforts in north america identified the geographical distribution of the disease and mechanisms underlying distribution, although the possibility of transmission to other cervids, including caribou, and noncervids, including humans, is not well understood. because of the documented importance of caribou (rangifer tarandu ...201627556568
chronic wasting disease drives population decline of white-tailed deer.chronic wasting disease (cwd) is an invariably fatal transmissible spongiform encephalopathy of white-tailed deer, mule deer, elk, and moose. despite a 100% fatality rate, areas of high prevalence, and increasingly expanding geographic endemic areas, little is known about the population-level effects of cwd in deer. to investigate these effects, we tested the null hypothesis that high prevalence cwd did not negatively impact white-tailed deer population sustainability. the specific objectives of ...201627575545
probiotic supplementation in children with cystic fibrosis-a systematic review.probiotics may benefit in cystic fibrosis (cf) as gut dysbiosis is associated with gastrointestinal symptoms and exacerbation of respiratory symptoms in cf. we conducted a systematic review of randomized controlled trials (rcts) and non-rcts of probiotic supplementation in children with cf, using the cochrane methodology, preferred reporting items for systematic reviews (prisma) statement, and meta-analysis of observational studies in epidemiology (moose) guidelines. primary outcomes were pulmon ...201627576473
association between epilepsy and systemic autoimmune diseases: a meta-analysis.to investigate the association between systemic autoimmune diseases (sad) and epilepsy and to determine whether the strength of this association is increased in the young.201627592469
rumen content stratification in the giraffe (giraffa camelopardalis).ruminants differ in the degree of rumen content stratification, with 'cattle-types' (i.e., the grazing and intermediate feeding ruminants) having stratified content, whereas 'moose-types' (i.e., the browsing ruminants) have unstratified content. the feeding ecology, as well as the digestive morphophysiology of the giraffe (giraffa camelopardalis), suggest that it is a 'moose-type' ruminant. correspondingly, the giraffe should have an unstratified rumen content and an even rumen papillation patte ...201727593451
the incidence of breast cancer among female flight attendants: an updated meta-analysis.several studies have indicated an increased risk of breast cancer (bc) among female flight attendants (ffas); however, the results from epidemiological studies were not consistent. we thus conducted an updated meta-analysis to re-assess the risk of bc among ffas, according to the moose guideline.201627601531
efficacy and safety of endoscopic third ventriculostomy and choroid plexus cauterization for infantile hydrocephalus: a systematic review and meta-analysis.endoscopic third ventriculostomy/choroid plexus cauterization (etv/cpc) has gained popularity in its treatment of infantile hydrocephalus over the past decade. in this manuscript, we perform a systematic review and meta-analysis to determine the efficacy and safety of etv/cpc, and to compare the procedural outcomes between north american and sub-saharan african cohorts.201627613635
prognostic significance of low microrna-218 expression in patients with different types of cancer: evidence from published studies.mounting evidence showed that micrornas may be useful as prognostic biomarkers of cancer. therefore, we summarize the predictive role of microrna-218 (mir-218) for survival in patients with various cancers.201627631228
first case of chronic wasting disease in europe in a norwegian free-ranging reindeer.chronic wasting disease (cwd) is a fatal contagious prion disease in cervids that is enzootic in some areas in north america. the disease has been found in deer, elk and moose in the usa and canada, and in south korea following the importation of infected animals. here we report the first case of cwd in europe, in a norwegian free-ranging reindeer in southern norway. the origin of the disease is unknown. until now a low number of cervids, and among them a few reindeer, have been tested for cwd i ...201627641251
arterial aneurysms associated with arteriovenous malformations of the brain: classification, incidence, risk of hemorrhage, and treatment-a systematic review.aneurysms associated with brain arteriovenous malformations (bavms) influence the natural history of these lesions and pose important therapeutic challenges. however, the epidemiology, natural history, and appropriate management of the aneurysms associated with bavms are not completely understood due to the paucity of large and uniform studies. we performed a systematic review of published series examining the association between aneurysms and bavms with the purpose of clarifying the prevalence, ...201627644700
markers for ongoing or previous hepatitis e virus infection are as common in wild ungulates as in humans in sweden.hepatitis e virus (hev) is a human pathogen with zoonotic spread, infecting both domestic and wild animals. about 17% of the swedish population is immune to hev, but few cases are reported annually, indicating that most infections are subclinical. however, clinical hepatitis e may also be overlooked. for identified cases, the source of infection is mostly unknown. in order to identify whether hev may be spread from wild game, the prevalence of markers for past and/or ongoing infection was invest ...201627657108
moose antler sign, a sign of deep endometriosis infiltrating bowel. 201627693682
a systematic review of iranian experiences in seismo-nephrology.crush syndrome and its potentially life-threatening complications, such as acute kidney injury (aki), are one of the most important medical problems of disaster victims. however, today, many unanswered questions abound about the potential risk factors of crush syndrome, predictive factors of aki, proper amount of prophylactic hydration therapy, type of fluid, time of continuing fluid, intravenous versus oral hydration, etc. therefore, this study was designed to review the findings on iranian nep ...201627703959
summer time predation on the obligatory off-host stage of an invasive ectoparasite.predation can regulate populations and strongly affect invasion success of novel prey. the deer ked (lipoptena cervi; linnaeus 1758) is an invasive ectoparasite of cervids that spends a long period of its life cycle outside the host. prior to this study, virtually nothing was known about natural summer time predation on the deer ked. we aimed to evaluate the magnitude of summer time predation on l. cervi pupae in different habitats and to identify potential predators. we conducted a set of field ...201627707426
cha2ds2-vasc risk factors as predictors of stroke after acute coronary syndrome: a systematic review and meta-analysis.stroke is a rare but serious complication of acute coronary syndrome. at present, no specific score exists to identify patients at higher risk. the aim of the present study is to test whether each clinical variable included in the cha2ds2-vasc score retains its predictive value in patients with recent acute coronary syndrome, irrespective of atrial fibrillation.201627708110
temporal patterns of moose-vehicle collisions with and without personal injuries.collisions with wild ungulates are an increasing traffic safety issue in boreal regions. crashes involving smaller-bodied deer species usually lead to vehicle damage only, whereas collisions with a large animal, such as the moose, increase the risk of personal injuries. it is therefore important to understand both the factors affecting the number of moose-vehicle collisions (mvcs) and the underlying causes that turn an mvc into an accident involving personal injuries or fatalities. as a basis fo ...201727723518
rumen microbiota for wild boreal cervids living in the same habitat.knowledge about the factors shaping the rumen microbiota in wild animals is limited. therefore, the aim of this study was to compare the microbiota from the three cervid species moose (alces alces, n = 5), red deer (cervus elaphus, n = 4) and roe deer (capreolus capreolus, n = 12), sharing the same habitat. using deep 16s rrna gene sequencing, we found that the largest species moose had the highest number of unique operational taxonomic units. furthermore, red deer and moose shared more of the m ...201627737946
relationship between cd and zn concentration in the kidneys, liver, and muscles of moose (alces alces) from north-eastern poland.the aim of the study was to evaluate the cadmium and zinc content in the kidneys and liver of moose from north-eastern poland. animals were divided with respect to their age. the mean concentration of cadmium in the kidneys of moose studied was 11.31 mg kg(-1), while in the liver it amounted to 2.68 mg kg(-1). age had a significant effect on the content of cadmium in both organs. in the muscles of most animals studied, the cadmium concentrations were below the detection limit. elevated concentra ...201727743325
prevalence of placenta previa among deliveries in mainland china: a prisma-compliant systematic review and meta-analysis.placenta previa is characterized by the abnormal placenta overlying the endocervical os, and it is known as one of the most feared adverse maternal and fetal-neonatal complications in obstetrics.201627749592
biomonitoring of selected persistent organic pollutants (pcdd/fs, pcbs and pbdes) in finnish and russian terrestrial and aquatic animal species.the finnish and russian animal species (semi-domesticated reindeer, finnish wild moose, baltic grey seal and baltic herring) samples were biomonitored in terrestrial and aquatic environments for polychlorinated dibenzo-p-dioxins and dibenzofurans (pcdd/fs), polychlorinated biphenyls (pcbs) and polybrominated diphenylethers (pbdes).201627752440
sarcocystis entzerothi n. sp. from the european roe deer (capreolus capreolus).in the present study, we describe sarcocystis entzerothi n. sp. from the european roe deer (capreolus capreolus) based on the microscopical and dna analysis. by light microscopy (lm), cysts of s. entzerothi were spindle-shaped with pointed tips, 950-1900 × 70-150 μm in size and had 5-6 μm long finger-like cyst wall protrusions. cyst wall of s. entzerothi by transmission electron microscopy (tem) was type 10a-like; villar protrusions were up to 1.2 μm wide, densely packed, lying about 0.1 μm betw ...201727752769
validity of recalled v. recorded birth weight: a systematic review and meta-analysis.low birth weight is associated with adverse health outcomes. if birth weight records are not available, studies may use recalled birth weight. it is unclear whether this is reliable. we performed a systematic review and meta-analysis of studies comparing recalled with recorded birth weights. we followed the meta-analyses of observational studies in epidemiology (moose) statement and preferred reporting items for systematic reviews and meta-analyses (prisma) guidelines. we searched medline, embas ...201727776565
moose on the loose: checklist for meta-analyses of observational studies. 201627790686
early and non-invasive detection of chronic wasting disease prions in elk feces by real-time quaking induced conversion.chronic wasting disease (cwd) is a fatal prion disease of wild and captive cervids in north america. prions are infectious agents composed of a misfolded version of a host-encoded protein, termed prpsc. infected cervids excrete and secrete prions, contributing to lateral transmission. geographical distribution is expanding and case numbers in wild cervids are increasing. recently, the first european cases of cwd have been reported in a wild reindeer and two moose from norway. therefore, methods ...201627829062
outcome of pancreas transplantation from donation after circulatory death compared to donation after brain death.to overcome the gap of organ shortage grafts from donation after circulatory death (dcd) can be used. this review evaluates the outcomes after dcd pancreas donation compared to donation after brain death (dbd).201727838258
hyponatremia and short-term prognosis of patients with acute pulmonary embolism: a meta-analysis.the aim of this study was to assess the relationship between hyponatremia and the short-term prognosis of patients with acute pulmonary embolism (pe).201727839808
female- and male-specific risk factors for stroke: a systematic review and meta-analysis.the incidence of stroke is higher in men than in women. the influence of sex-specific risk factors on stroke incidence and mortality is largely unknown.201727842176
prognostic value of microrna-9 in various cancers: a meta-analysis.recently, there are more and more evidences from studies have revealed the association between microrna-9 (mir-9) expression and outcome in multiple cancers, but inconsistent results have also been reported. it is necessary to rationalize a meta analysis of all available data to clarify the prognostic role of mir-9. eligible studies were selected through multiple search strategies and the quality was assessed by moose. data was extracted from studies according to the key statistics index. all an ...201627844330
bacterial genomics reveal the complex epidemiology of an emerging pathogen in arctic and boreal ungulates.northern ecosystems are currently experiencing unprecedented ecological change, largely driven by a rapidly changing climate. pathogen range expansion, and emergence and altered patterns of infectious disease, are increasingly reported in wildlife at high latitudes. understanding the causes and consequences of shifting pathogen diversity and host-pathogen interactions in these ecosystems is important for wildlife conservation, and for indigenous populations that depend on wildlife. among the key ...201627872617
do emergency medicine journals promote trial registration and adherence to reporting guidelines? a survey of "instructions for authors".the aim of this study was to evaluate the current state of two publication practices, reporting guidelines requirements and clinical trial registration requirements, by analyzing the "instructions for authors" of emergency medicine journals.201627881175
multiple browsers structure tree recruitment in logged temperate forests.historical extirpations have resulted in depauperate large herbivore assemblages in many northern forests. in eastern north america, most forests are inhabited by a single wild ungulate species, white-tailed deer (odocoileus virginianus), and relationships between deer densities and impacts on forest regeneration are correspondingly well documented. recent recolonizations by moose (alces americanus) in northeastern regions complicate established deer density thresholds and predictions of browsin ...201627893758
current construct options for revision of large acetabular defects: a systematic review.many treatment options are available for the revision of large acetabular defects. debate continues as to which technique is most effective.201627922983
prognostic implications of aspiration pneumonia in patients with community acquired pneumonia: a systematic review with meta-analysis.aspiration pneumonia is thought to be associated with a poor outcome in patients with community acquired pneumonia (cap). however, there has been no systematic review regarding the impact of aspiration pneumonia on the outcomes in patients with cap. this review was conducted using the moose guidelines: patients: patients defined cap.201627924871
new roles in hemicellulosic sugar fermentation for the uncultivated bacteroidetes family bs11.ruminants have co-evolved with their gastrointestinal microbial communities that digest plant materials to provide energy for the host. some arctic and boreal ruminants have already shown to be vulnerable to dietary shifts caused by changing climate, yet we know little about the metabolic capacity of the ruminant microbiome in these animals. here, we use meta-omics approaches to sample rumen fluid microbial communities from alaskan moose foraging along a seasonal lignocellulose gradient. winter ...201727959345
implementation of a vaccine screening program at an independent community pharmacy.to implement a comprehensive vaccine screening program and to identify best practices in workflow for a vaccine screening program.201727964886
homocysteine and risk of age-related macular degeneration: a systematic review and meta-analysis.there is still no agreement on total plasma homocysteine (thcy) role in age-related macular degeneration (amd), the leading cause of new blindness in industrialized countries. we performed a systematic review and meta-analysis of the published data on the correlation between thcy and amd. medline/pubmed and isi web of sciences searches were performed according to moose guidelines. case-control studies were eligible for inclusion. participants and controls were amd patients and subjects without a ...201627966830
rituximab shows no effect on remission in patients with refractory nephrotic syndrome: a moose-compliant meta-analysis.to assess the efficacy of rituximab in treatment of refractory nephrotic syndrome (ns) compared with other agents.studies were searched from web of science, pubmed, and cnki up to april 2016. the standardized mean difference or relative risk or odds ratio and 95% confidence intervals were used to assess the efficacy of rituximab treatment compared with other agents in refractory ns.totally, 8 studies were included. the present study showed that there was a significant higher relapse-free surviva ...201627977574
migraine affects 1 in 10 people worldwide featuring recent rise: a systematic review and meta-analysis of community-based studies involving 6 million participants.to study the weighted average global prevalence of migraine at the community level.201728017235
prey selection of scandinavian wolves: single large or several small?research on large predator-prey interactions are often limited to the predators' primary prey, with the potential for prey switching in systems with multiple ungulate species rarely investigated. we evaluated wolf (canis lupus) prey selection at two different spatial scales, i.e., inter- and intra-territorial, using data from 409 ungulate wolf-kills in an expanding wolf population in scandinavia. this expansion includes a change from a one-prey into a two-prey system with variable densities of o ...201628030549
swimming attendance during childhood and development of asthma: meta-analysis.the association between asthma and swimming pool attendance has not been demonstrated and currently there are conflicting results. in order to clarify the association between asthma diagnosis in children and swimming pool attendance, and to assess the consistency of the available epidemiological studies, we completed a literature analysis on the relationship between the exposure to disinfection by-products in indoor swimming pools during childhood and asthma diagnosis.201628032933
mobility of moose-comparing the effects of wolf predation risk, reproductive status, and seasonality.in a predator-prey system, prey species may adapt to the presence of predators with behavioral changes such as increased vigilance, shifting habitats, or changes in their mobility. in north america, moose (alces alces) have shown behavioral adaptations to presence of predators, but such antipredator behavioral responses have not yet been found in scandinavian moose in response to the recolonization of wolves (canis lupus). we studied travel speed and direction of movement of gps-collared female ...201628035275
association of cannabis use with the development of elevated anxiety symptoms in the general population: a meta-analysis.the directionality and magnitude of the association of cannabis use with elevated anxiety symptoms in the general population is unclear. the aim of this meta-analysis was to investigate the association of cannabis use with the development of elevated anxiety symptoms in the general population.201728053188
diabetes is associated with risk of postoperative cognitive dysfunction: a meta-analysis.postoperative cognitive dysfunction (pocd) occurs frequently after surgery, particularly among older people. diabetes, chronic hyperglycemia, and a history of hypoglycemia are related to cognitive impairment, but little is known about their roles in pocd. here, we estimated their associations with risk of pocd on the basis of published epidemiological research.201728063267
ungulate predation and ecological roles of wolves and coyotes in eastern north america.understanding the ecological roles of species that influence ecosystem processes is a central goal of ecology and conservation biology. eastern coyotes (canis latrans) have ascended to the role of apex predator across much of eastern north america since the extirpation of wolves (canis spp.) and there has been considerable confusion regarding their ability to prey on ungulates and their ecological niche relative to wolves. eastern wolves (c. lycaon) are thought to have been the historical top pr ...201728064464
habitat-performance relationships of a large mammal on a predator-free island dominated by humans.the demographic consequences of changes in habitat use driven by human modification of landscape, and/or changes in climate, are important for any species. we investigated habitat-performance relationships in a declining island population of a large mammal, the moose (alces alces), in an environment that is predator-free but dominated by humans. we used a combination of demographic data, knowledge of habitat selection, and multiannual movement data of female moose (n = 17) to understand how spac ...201728070294
total bilirubin level may be a biomarker of nephropathy in type 2 diabetes mellitus: a meta-analysis of observational studies based on moose compliant.recently, the number of the studies on the relationship between the total bilirubin level (tbl) and diabetic nephropathy (dn) is increasing, but their results were not consistent. therefore, we performed a meta-analysis to analyze the relationship between tbl and the risk of dn.we searched 5 databases before october 31, 2016, and reviewed the reference list of relevant articles. the fixed or random-effects model was used to pool risk estimates. we conducted the dose-response meta-analysis to eva ...201728072721
a meta-analysis of the clinicopathological characteristics and survival outcomes of inflammatory bowel disease associated colorectal cancer.the current study aims to use meta-analytical techniques to compare the clinicopathological characteristics and survival outcomes of inflammatory bowel disease (ibd) associated and sporadic colorectal carcinoma (crc). patients with ibd have an established increased risk of developing crc. there is no consensus, however, on the clinicopathological characteristics and survival outcomes of ibd associated crc when compared to sporadic crc.201728078433
prevalence of obesity and overweight in african learners: a protocol for systematic review and meta-analysis.obesity and overweight are an emerging problem in africa. obese children are at increased risk of developing hypertension, high cholesterol, orthopaedic problems and type 2 diabetes as well as increased risk of adult obesity. prevention of childhood overweight and obesity therefore needs high priority. the review approach is particularly useful in establishing whether research findings are consistent and can be generalised across populations and settings. this systematic review aims to assess th ...201728087553
the incidence of postpartum hemorrhage in pregnant women with placenta previa: a systematic review and meta-analysis.the global burden of postpartum hemorrhage (pph) in women with placenta previa is a major public health concern. although there are different reports on the incidence of pph in different countries, to date, no research has reviewed them.201728107460
the structure of mammalian prions and their aggregates.prion diseases, such as creutzfeldt-jakob disease in humans, bovine spongiform encephalopathy in cattle, chronic wasting disease in cervids (i.e., deer, elk, moose, and reindeer), and sheep scrapie, are caused by the misfolding of the cellular prion protein (prp(c)) into a disease-causing conformer (prp(sc)). prp(c) is a normal, gpi-anchored protein that is expressed on the surface of neurons and other cell types. the structure of prp(c) is well understood, based on studies of recombinant prp, w ...201728109330
hematology journals do not sufficiently adhere to reporting guidelines: a systematic review.essentials reporting guidelines and trial/review registration aim to limit bias in research. we systematically reviewed hematology journals to examine the use of these policies. forty-eight percent of journals made no use of these policies. improving the use of reporting guidelines will improve research for all stakeholders.201728122156
effects of interspecific interaction-linked habitat factors on moose resource selection and environmental stress.resource selection of herbivores is a complex ecological process that operates in relation to biological or non-biological factors, which may affect the feeding and movement, and subsequently their spatial distribution and environmental stress. here, we estimated moose (alces alces cameloides) resource selection for habitat variables and the effect of interspecific interactions related to roe deer (capreolus pygargus bedfordi) on its population distribution and environmental stress in the khinga ...201728128311
de novo generation of a unique cervid prion strain using protein misfolding cyclic amplification.substantial evidence supports the hypothesis that prions are misfolded, infectious, insoluble, and protease-resistant proteins (prp(res)) devoid of instructional nucleic acid that cause transmissible spongiform encephalopathies (tses). protein misfolding cyclic amplification (pmca) has provided additional evidence that prpres acts as a template that can convert the normal cellular prion protein (prp(c)) present in uninfected normal brain homogenate (nbh) into the infectious misfolded prp(res) is ...201728144628
serum selenium levels and prostate cancer risk: a moose-compliant meta-analysis.some observational studies have shown that elevated serum selenium levels are associated with reduced prostate cancer risk; however, not all published studies support these results. a literature search of pubmed, embase, medline, and the cochrane library up until september 2016 identified 17 studies suitable for further investigation. a meta-analysis was conducted on these studies to investigate the association between serum selenium levels and subsequent prostate cancer risk. pooled odds ratios ...201728151881
prevalence of type 2 diabetes in nepal: a systematic review and meta-analysis from 2000 to 2014.background understanding the prevalence of type 2 diabetes in nepal can help in planning for health services and recognising risk factors. this review aims to systematically identify and collate studies describing the prevalence of type 2 diabetes, to summarise the findings, and to explore selected factors that may influence prevalence estimates. design this systematic review was conducted in adherence to the moose guidelines for meta-analysis and systematic reviews of observational studies. med ...201528156709
gastrojejunostomy tube complications - a single center experience and systematic review.gastrojejunostomy tubes (gjts) enable enteral nutrition in infants/children with feeding intolerance. however, complications may be increased in small infants. we evaluated our single-institution gjt complication rate and systematically reviewed existing literature.201728162764
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