Publications

TitleAbstractYear
Filter
PMID(sorted ascending)
Filter
piezoelectric driven non-toxic injector for automated cell manipulation.stimulated by state-of-the-art robotic and computer technology, intra cytoplasmic sperm injection (icsi) automation aims to scale and seamlessly transfer the human hand movements into more precise and fast movements of the micro manipulator. piezo-drill cell injection, a novel technique using piezo-driven pipettes with a very small mercury column, has significantly improves the survival rates of icsi process. it is found that complications are due, in large part, to toxicity of mercury and the d ...201121335794
mechatronic assistant system for dental drill handling.holding a dental tool for many hours of work is reflected in fatigue and manual tremor, which causes bad handling of rotatory instruments and consequently injuries within the buccal cavity. at present there exists no system to help the medical dentist in the support and handling of the dental drill. we propose the use of a mechatronic system to help the odontologist in handling the dental drill.201021341359
evaluation of a neurosurgical robotic system to make accurate burr holes.neurosurgery has been driven forward by the latest breakthroughs in technology that combine science and engineering. neurosurgical robotic systems are a good example of such a breakthrough that has several potential advantages over existing techniques. this study sought to evaluate the pathfinder robotic system in order to establish whether it is capable of carrying out burr hole procedures in specific locations in human skull replicas, along predetermined trajectories and for precise depths.201121341368
[study on the change of dune co2 concentration in the autumn at minqin in tengger desert].in order to find out the co2 concentration of the desert area, the influence of it on the co2 in the atmosphere and the role that it played on the global carbon cycle, the research team utilized in september 2009 infrared co2 monitor to observe the co2 concentration of the 12 drill holes day and night in minqin desert area in the tengger desert. the difference of various observation spots' co2 concentration of the desert area in the tengger desert area is relatively big. the co2 concentration at ...201021360892
the use of cone-beam computed tomography and digital periapical radiographs to diagnose root perforations.the aim of this study was to compare the sensitivity and specificity of cone-beam computed tomography (cbct) scans and digital periapical radiographs (pr) in detecting strip and root perforations after root canal treatment in mandibular molars.201121419300
impaired bone healing pattern in mice with ovariectomy-induced osteoporosis: a drill-hole defect model.to establish a drill-hole defect model in osteoporotic mouse femur by comparing temporal cortical bone healing pattern between ovx-induced osteoporotic bone and sham-operated bone.201121421090
[acoustic-mechanical trauma during cochleostomy: animal experimental studies].when performing cochlear implant (ci) surgery in ears with residual hearing, cochlear function should be preserved as far as possible. besides non-traumatic electrode insertion the acoustic-mechanical trauma of the cochleostomy should be minimized. according to experiences from temporal bone preparations the hypothesis that thorough exposition of the endosteal membrane with the drill prior to opening the cochlea might constitute a bigger acoustic mechanical trauma than direct drilling of the inn ...201121424134
microdialysis in the femoral head of the minipig and in a blood cloth of human blood.microdialysis can detect ischemia in soft tissue. in a previous study, we have shown the development of ischemia in the femoral head removed from patients undergoing total hip replacement. that study also raised some methodological questions that this study tries to answer: what is happening in the dead space around the catheter in the drill canal, and is there an equilibrium period after the insertion of the catheter?201121428845
talking to iraq and afghanistan war veterans about tobacco use.our goal in this study was to examine beliefs and attitudes about tobacco use in the newest generation of combat veterans, those who served in afghanistan (operation enduring freedom [oef]) and iraq (operation iraqi freedom [oif]).201121436295
surgical preparation of bone-scaffold interface is critical for bone regeneration inside tissue engineering scaffold.the goal of this study was to investigate if the preparation of implantation site affects bone formation inside tissue engineering scaffolds. for this purpose, two different drilling techniques were used to create a hole in distal femurs of rats before the insertion of a bone scaffold: a manually driven wood drill bit and an electrically driven metal drill bit. the size and the position of the hole were identical for the two cases. the bone volume, bone mineral density, and callus formation were ...201121437957
onlay and inlay bone grafts with platelet-rich plasma: histologic evaluations from human biopsies.the aim of the present study was to histomorphometrically evaluate biopsies from 1) sinus inlay bone grafts prepared with or without platelet-rich plasma (prp) and 2) onlay bone grafts in the anterior maxilla with particulate bone and prp or block bone without prp after 3 months.201121440827
human adipose derived stem cells reduce callus volume upon bmp-2 administration in bone regeneration.the demand for new therapeutic approaches to treat bone defects and fractures is increasing in trauma surgery and orthopaedics because the number of patients with degenerative diseases is continuously growing. "tissue engineering" offers promising new technologies that combine the three components - cells, growth factors and matrix. efforts are targeted at improving and accelerating recovery, especially for long bone fractures, and reducing the risk of delayed bone healing or pseudoarthrosis. ad ...201121457972
impact of bone quality, implant type, and implantation site preparation on insertion torques of mini-implants used for orthodontic anchorage.mini-implants are widely used as skeletal anchorage in orthodontics. to reduce implant loss rate, sufficient primary stability is required. this study quantitatively analysed the impact of bone quality and pre-drilling diameter on the insertion torque of five different mini-implants. twenty pig bone segments were dissected and embedded in resin. the insertion torques of two different mini-implant types (tomas pin, dentaurum, germany, 8 and 10 mm; and dual top, jeil, korea, 1.6 mm × 8 and 10 mm p ...201121458232
fracture prevention by femoroplasty-cement augmentation of the proximal femur.the prevention of hip fractures is a desirable goal to reduce morbidity, mortality, and socio-economic burden. we evaluated the influence on femoral strength of different clinically applicable cementing techniques as "femoroplasty." twenty-eight human cadaveric femora were augmented by means of four clinically applicable percutaneous cementing techniques and then tested biomechanically against their native contralateral control to determine fracture strength in an established biomechanical model ...201121500251
minimally invasive computer-assisted approach for cochlear implantation: a human temporal bone study.computer-assisted navigation systems can now potentially guide the surgeon to the cochlea with a trajectory avoiding the facial nerve through a keyhole approach. five temporal bone specimens, with 4 titanium screws placed in the mastoid cortex, were studied. preoperative computed tomographic scan images were loaded on an electromagnetic computer-assisted surgery (cas) system (digipointeur, collin, bagneux, france). a drill was connected to the cas to monitor its progression continuously. a conic ...201121502203
biocompatibility and bone formation of flexible, cotton wool-like plga/calcium phosphate nanocomposites in sheep.the purpose of this preliminary study was to assess the in vivo performance of synthetic, cotton wool-like nanocomposites consisting of a biodegradable poly(lactide-co-glycolide) fibrous matrix and containing either calcium phosphate nanoparticles (plga/cap 60:40) or silver doped cap nanoparticles (plga/ag-cap 60:40). besides its extraordinary in vitro bioactivity the latter biomaterial (0.4 wt% total silver concentration) provides additional antimicrobial properties for treating bone defects ex ...201121566736
cartilaginous repair of full-thickness articular cartilage defects is induced by the intermittent activation of pth/pthrp signaling.objective: we studied the effects of the transient activation of parathyroid hormone (pth)/pth-related peptide (pthrp) signaling during the repair of 5-mm-diameter full-thickness defects of articular cartilage in the rabbit. materials and methods: cylindrical full-thickness articular cartilage defects of 5mm in diameter were artificially created in the femoral trochlea of male adolescent japanese white rabbits using a hand-drill. recombinant human pth(1-84) was then administered into the joint c ...201121571083
osteopontin and wound healing in bone.bone wound healing after surgical drilling/cutting initially involves a typical inflammatory response with a leukocyte-rich cell infiltrate whose professional phagocytes (neutrophils and macrophages) clear the wound site of various bacterial (if present), particulate, and insoluble components arising from the original wounding event. as part of this process, in a surgical model of bone repair in rats, osteopontin (opn) secreted by macrophages - with its known mineral-binding properties arising f ...201121576907
revitalization of cortical bone allograft by application of vascularized scaffolds seeded with osteogenic induced adipose tissue derived stem cells in a rabbit model.background: adipogenous tissue derived stem cells (asc) are available in abundance in the human body and can differentiate in the presence of lineage-specific induction factors, for example, in myogenic, adipogenic, chondrogenic and osteogenic cells. the aim of this study was to evaluate the impact of osteogenic induced asc's (o-asc) on revascularization and cellular repopulation of avital cortical bone employing a vascularized bovine scaffold. methods: an inguinal arterio-venous bundle was diss ...201121594572
the effect of drilling and screw fixation of the growth plate-an experimental study in rabbits.injury of the growth plate is a specific problem in traumatology and can cause limb deformity and length discrepancy as a result of growth arrest. the purpose of this study was to evaluate alterations of the growth plate after artificially created injuries. a total of 14 new zealand white rabbits were used for this experiment. the right and left ulna of each animal was used resulting in a total of 28 ulnae. in six animals drill holes were driven into the growth plate either from the distal/epiph ...201121618598
effect of alveolex on the bone defects repair stimulated by rhbmp-2: histomorphometric study.objective: the aim of this study was to evaluate histomorphometrically the effect of alveolex (propolis 10%) on the repair of bone cavities in the calvaria of rats. materials and methods: a 5 mm diameter bone defect was made in the calvaria of male wistar rats using the drill-type trephine. the defects were filled with rhbmp-2+alveolex, rhbmp-2, alveolex, or coagulum. twenty-eight animals with seven subjects on each were sacrificed 30 days after surgery and samples were fixed and embedded in par ...201121618653
characterization of subchondral bone repair for marrow-stimulated chondral defects and its relationship to articular cartilage resurfacing.background: microfracture and drilling are bone marrow-stimulation techniques that initiate cartilage repair by providing access to cell populations in subchondral bone marrow. this study examined the effect of hole depth and of microfracture versus drilling on subchondral bone repair and cartilage repair in full-thickness chondral defects. hypotheses: repaired subchondral bone does not reconstitute its native structure and exhibits atypical morphologic features. drilling deeper induces greater ...201121628638
a broken drill-bit fragment causing severe radiating pain after cervical total disc replacement: a case report.this is a case report of a 38-year-old man with severe radiating pain on upper extremity after cervical total disc replacement (tdr). we faced an unusual complication that has not been reported yet. he underwent cervical tdr for left central disc protrusion on c5-6. after the surgery, preoperative symptom disappeared. however, at postoperative 1 year, he complained severe right-sided radiating pain that had a sudden onset. on postoperative x-ray, a metal fragment which seemed like a broken drill ...201121629488
a novel quercetin analog from a medicinal plant promotes peak bone mass achievement, bone healing after injury and exerts anabolic effect on osteoporotic bone: the role of aryl hydrocarbon receptor as a mediator of osteogenic action.we recently reported that extracts made from the stem-bark of ulmus wallichiana promoted the peak bone mass achievement in growing rats, and preserved trabecular bone mass and cortical bone strength in ovariectomized (ovx) rats. further, 6-c-β-d-glucopyranosyl-(2s,3s)-(+)-3',4',5,7-tetrahydroxyflavanol (gtdf), a novel flavonol-c-glucoside isolated from the extracts had a non-estrogenic bone sparing effects on ovx rats. here we studied the effects of gtdf on osteoblast function and its mode of ac ...201121638315
surviving of bovine teeth adhesively restored with 3 types of fiber post after fatigue resistance.aim of this study was to evaluate the fatigue resistance of bovine roots adhesively restored with three fiber posts.201121666566
proximal humerus shaft fracture after pectoralis major tendon rupture repair.surgical repair of a complete pectoralis major tendon rupture at the humeral insertion has superior results compared to nonoperative treatment. to our knowledge, a proximal humerus shaft fracture occurring at the site of the bone trough and cortical drill holes after a pectoralis major tendon rupture repair has not been reported in the literature.a 45-year-old man sustained an acute left pectoralis major tendon rupture at the humeral insertion while performing a bench press maneuver. he underwen ...201121667914
measuring exposed magnetic fields of welders in working time.the assessment of the occupational electromagnetic field exposure of welders is of great importance, especially in shielded-arc welding, which uses relatively high electric currents of up to several hundred amperes. in the present study, we measured the magnetic field exposure level of welders in the course of working. a 3-axis hall magnetometer was attached to a subject's wrist in order to place the sensor probe at the closest position to the magnetic source (a cable from the current source). d ...201121670555
depth of subchondral perforation influences the outcome of bone marrow stimulation cartilage repair.subchondral drilling and microfracture are bone marrow stimulation techniques commonly used for the treatment of cartilage defects. few studies to date have examined the technical variants which may influence the success of the cartilage repair procedures. this study compared the effect of hole depth (6ôçëmm vs. 2ôçëmm) and hole type (drill vs. microfracture) on chondral defect repair using a mature rabbit model. results from quantitative histomorphometry and histological scoring showed that dee ...201121671261
piezosurgery prevents brain tissue damage: an experimental study on a new rat model.piezosurgery is a promising meticulous system for bone cutting, based on ultrasound microvibrations. it is thought that the impact of piezosurgery on the integrity of soft tissue is generally low, but it has not been examined critically. the authors undertook an experimental study to evaluate the brain tissue response to skull bone removal using piezosurgery compared with a conventional drilling method. in wistar male rats, a circular bone window was drilled to the parietal bone using piezosurge ...201121676589
direct delayed human adenoviral bmp-2 or bmp-6 gene therapy for bone and cartilage regeneration in a pony osteochondral model.to evaluate healing of surgically created large osteochondral defects in a weight-bearing femoral condyle in response to delayed percutaneous direct injection of adenoviral (ad) vectors containing coding regions for either human bone morphogenetic proteins 2 (bmp-2) or -6.201121683796
predictors of acceptance of h1n1 influenza vaccination by fdny firefighters and ems workers.there is a widely recognized need for vaccination of health care workers (hcws). we undertook this study to assess the 2009-2010 h1n1 vaccination rates in ôê+14,000 firefighters and emergency medical service (ems) workers at the fire department of new york (fdny) and to determine predictors of h1n1 vaccine acceptance.201121693157
risk factors for fibular fracture after tplo.objective: to determine (1) risk factors for fibular fracture after tibial plateau leveling osteotomy (tplo) and (2) if a single postoperative radiographic measurement or measurement ratio of the proximal tibial fragment can be used as a predictor for fibular fracture. study design: multivariate retrospective clinical study. animals: dogs (n=326) with cranial cruciate ligament rupture that had tplo (n=355). methods: medical records (january 2004-november 2007) and radiographs of dogs that had tp ...201121699551
influence of orthopaedic drilling parameters on temperature and histopathology of bovine tibia: an in vitro study.orthopaedic drilling operations without optimum operating parameters by surgeons may cause bone defects such as bone fracture, cracks, osteolysis and tissue loss around the drilling zone. for the sake of optimum drilling parameters, an in vitro study was performed by considering the bone mineral density, bone sex, drill tip angle, drill speed, drill force and feed-rate. the specimens were taken from the drilled sites of fresh male and female calf tibias. the temperature changes at the drill site ...201121703907
precision of tunnel positioning in navigated anterior cruciate ligament reconstruction.the aim of this study was to validate the precision of navigated tunnel positioning using a fluoroscopy-based computer-assisted technique.201121704470
sowing simulation tests of a pneumatic drill equipped with systems aimed at reducing the emission of abrasion dust from maize dressed seed.the utilization of dressed seed for spring sowing is a widespread practice to control some pests with reduced doses of chemical products. however some insecticides employed in maize seed dressing, namely belonging to the neonicotinoid family and fipronil, have been claimed to play a role in the decline of honeybees (apis mellifera l.). pneumatic drills used in maize sowing are charged with contributing to the dispersion of the abrasion dust produced by dressed seeds, favoring the contamination o ...201121726139
preliminary study on persistence in soil and residues in maize of imidacloprid.the aim of this work was to study the distribution of imidacloprid in soil and its translocation to roots and aerial parts of maize plant. the main objective was to assess imidacloprid residues in field environment, in order to provide data on honeybees exposure level to such an active substance. imidacloprid has been detected and quantified by triple quadrupole hplc-ms-ms. pesticide persistence in the soil and its residues in pollen and in maize plants have been evaluated during the growing of ...201121726143
assessment of a bone biopsy technique for measuring tiludronate in horses: a preliminary study.this study assessed the feasibility of measuring tiludronate in horses using a minimally invasive bone biopsy technique. eight horses were treated with intravenous (iv) tiludronate [1 mg/kg bodyweight (bw)], either once (n = 4) or twice, 28 d apart (n = 4). the horses that were treated once were euthanized on days 1, 43, 57, or 92 and those that were treated twice, were euthanized on days 112, 154, 194, or 364. bone samples were taken bilaterally from each horse at 4 sites: the third metacarpal ...201121731184
xenograft bone inclusion improves incorporation of hydroxyapatite cement into cancellous defects.hydroxyapatite cement (hac) is biocompatible and osteoconductive, but its slow resorption limits new bone formation. the purpose of this investigation was to determine the effects of adding partially demineralized xenograft cortical bone in an established animal model.201121738066
study of the osteoconductive capacity of hydroxyapatite implanted into the femur of ovariectomized rats.osteoporosis is a global public health that affects postmenopausal women due to the deficiency of estrogen, a hormone that plays an important role in the microarchitecture of bone tissue. osteoporosis predisposes to pathological bone fracture that can be repaired by conventional methods. however, depending on the severity and quantity of bone loss, the use of autogenous grafts or biomaterials such as hydroxyapatite might be necessary. the latter has received increasing attention in the medical f ...201121761494
accuracy of a newly developed cbct-aided surgical guidance system for dental implant placement: an ex vivo study.abstract the aim of the present study was to measure the accuracy of the cbct-aided stentcad®beyond (ay tasarim ltd., ankara, turkey) surgical guidance system and to compare bone-supported and tooth/bone-supported guidance by using this system in dental implant placement ex vivo. five cadaver mandibles were scanned using an iluma cbct (3m imtec, oklahoma, usa) scanner. after scanning, dicom slices were transferred to the stentcad®beyond implant simulation software, which was used for preoperativ ...201121767205
repair of monteggia fractures using an arthrex tightrope system and ulnar plating.objective: to report the outcome after treatment of monteggia fractures (mf) using a novel surgical technique. study design: clinical reports. methods: one dog and 1 cat were treated for mf by use of a tightrope suture, toggle, and button implant. in both patients the fracture/luxations were reduced using an open technique and the tightrope was placed using a cannulated drill system and guide wire from cranial to caudal. cases were retrospectively reviewed at 1, 5, and 8 weeks (cat) and at 4 wee ...201121770974
effects of multiple drilling on the ischemic capital femoral epiphysis of immature piglets.purpose: this study investigated the effects of multiple drilling on the immature capital femoral epiphysis following ischemic injury in a piglet model. materials and methods: ischemic necrosis of capital femoral epiphysis was induced bilaterally in 12 piglets using a cervical ligation method. three weeks later, medial, central, and lateral 3 drill holes were made on the left femoral head using 0.062" k-wire. at 3, 6, 9, and 12 weeks following the multiple drilling, femoral heads were harvested ...201121786447
screw motion regulates multiple functions of t4 phage protein gp5 during cell puncturing.bacteriophage t4 penetrates the outer membrane of escherichia coli using a multifunctional device composed of a gene product 5 (gp5) protein trimer. we report that gp5 sequentially exerts distinct functions along the course of penetration stages induced by screw motion. a triple-stranded ß-helix of gp5 act as a cell-puncturing drill bit to make a hole on the membrane and then send the lipids upwards efficiently by strong charge interactions. the gp5 lysozyme domains, which degrade the peptidogly ...201121793574
thermal changes and drill wear in bovine bone during implant site preparation. a comparative in vitro study: twisted stainless steel and ceramic drills.objectives: the purpose was to assess thermal changes and drill wear in bovine bone tissue with the use of twisted stainless steel and zirconia-based drills, during implant site preparation. methods: a total of 100 implant site preparations were performed on bovine ribs using a surgical unit linked to a testing device, in order to standardize/simulate implant drilling procedures. bone temperature variations and drilling force were recorded when drilling at a depth of 8 and 10 mm. a constant irri ...201121806686
evaluation of the in vitro cell-material interactions and in vivo osteo-integration of a spinal acrylic bone cement.introduction: polymethylmethacrylate bone cements have proven performance in arthroplasty and represent a common bone filler, e.g. in vertebroplasty. however, acrylic cements are still subject to controversy concerning their exothermic reaction and osteo-integration potential. therefore, we submitted a highly filled acrylic cement to a systematic investigation on the cell-material and tissue-implant response in vitro and in vivo. materials and methods: cured vertecem v+ cements were characterize ...201121811821
are terminally threaded guide pins from cannulated screw systems dangerous?threaded and smooth pins are often used in orthopedic surgery. although uncommon, injury to the soft tissues can and do occur, including nerve or vessel injury from aberrant pin placement. the purpose of this study was to compare the risk of nerve injury from threaded pins versus smooth guide pins due to: (1) past-point-drilling of the pin, or (2) entanglement of the pin with soft tissue. past-point drilling was tested by a blindfolded participant drilling a 1.6-mm guide pin (terminally threaded ...201121815579
comparison of the effects of low-level laser therapy and low-intensity pulsed ultrasound on the process of bone repair in the rat tibia.background: electrophysical agents such as ultrasound (us) and low-level laser therapy (lllt) have been increasingly used in physical therapy practice. studies suggest that these devices are able to stimulate osteoblast proliferation and osteogenesis at the fracture site, resulting in a greater deposition of bone mass and speeding up the consolidation process. objective: the aim of this study was to analyze the effects of us and lllt on the bone healing process, through biomechanical and histolo ...201121829983
aortic hammer syndrome.to present a case of penetrating aortic ulcer with extraordinary etiology.201121861736
accuracy of a cone beam computed tomography-guided surgical stent for orthodontic mini-implant placement.abstract objective: to validate the accuracy of a cone-beam computed tomography (cbct)-guided surgical stent for orthodontic mini-implant (omi) placement by quantitatively evaluating the difference between cbct-prescribed and actual position of mini-implants in preoperative and postoperative cbct images. materials and methods: a surgical stent was fabricated using teflon-perfluoroalkoxy, which has appropriate biological x-ray attenuation properties. polyvinylsiloxane impression material was used ...201121875317
induced pluripotent stem cells from highly endangered species.for some highly endangered species there are too few reproductively capable animals to maintain adequate genetic diversity, and extraordinary measures are necessary to prevent extinction. we report generation of induced pluripotent stem cells (ipscs) from two endangered species: a primate, the drill, mandrillus leucophaeus and the nearly extinct northern white rhinoceros, ceratotherium simum cottoni. ipscs may eventually facilitate reintroduction of genetic material into breeding populations.201121892153
Remediation of oil-based drill cuttings through a biosurfactant-based washing followed by a biodegradation treatment.In this study, oil-based drill cuttings were washed by a rhamnolipid solution and then subjected to bioremediation in stainless steel boxes using sawdust as bulking agent. A mixed bacterial culture, mainly containing Pseudomonas, Acinetobacter, Alcaligenes, Agrobacterium, and Comamonas, was used as inoculums. Approximately 83% of organics were removed after washing under optimal conditions (liquid/solid ratio, 3:1; washing time, 20 min; stirring speed, 200 rpm; rhamnolipid concentration, 360 mg/ ...201121925873
[anatomic comparison between spinous process screws and pedicle screws techniques of the second cervical vertebar].to compare anatomic difference between spinous process screws and pedicle screws techniques of the second cervical vertebra.201121928672
osteogenic potential of autogenous bone grafts harvested with four different surgical techniques.the osteogenic potential of autogenous bone grafts is superior to that of allografts and xenografts because of their ability to release osteoinductive growth factors and provide a natural osteoconductive surface for cell attachment and growth. in this in vitro study, autogenous bone particles were harvested by four commonly used techniques and compared for their ability to promote an osteogenic response. primary osteoblasts were isolated and seeded on autogenous bone grafts prepared from the man ...201121940523
Microdrilled Cartilage Defects Treated with Thrombin-Solidified Chitosan/Blood Implant Regenerate a More Hyaline, Stable, and Structurally Integrated Osteochondral Unit Compared to Drilled Controls.This study analyzed the long-term cartilage and subchondral bone repair of microdrilled defects treated with chitosan glycerol-phosphate/blood implant, using thrombin (Factor IIa) to accelerate in situ solidification. We also evaluated the cartilage repair response to six smaller microdrill holes compared with two larger holes. Bilateral knee trochlear cartilage defects were created in n=8 skeletally mature rabbits, drilled with six proximal 0.5?mm and two distal 0.9?mm holes, then covered with ...201121942869
a pilot comparison of laser-assisted vs piezo drill icsi for the in vitro production of horse embryos.intracytoplasmic sperm injection (icsi) is the method of choice for the in vitro production (ivp) of equine embryos. however, conventional icsi has been associated with mechanical damage to the oocyte caused by the deformation of the zona pellucida (zp) and exposure of the oolemma to negative pressure during injection. introduction of the less traumatic and more efficient piezo drill-assisted icsi (pdai) yielded higher cleavage rates and more consistent results. nevertheless, pdai is also associ ...201121950451
Early partial monolateral zygomatic arch defect leads to unilateral craniofacial malformation.This study used reconstructed three-dimensional imaging to examine the influence of early partial monolateral zygomatic arch defect on the craniofacial development in a minipig model.201121959455
Histomorphometric analysis of the repair process of autogenous bone grafts fixed at rat calvaria with cyanoacrylate.The purpose of this study was to perform histological and histometric analyses of the repair process of autogenous bone grafts fixed at rat calvaria with ethyl-cyanoacrylate adhesive.201121986659
the rat intervertebral disk degeneration pain model: relationships between biological and structural alterations and pain.abstract: introduction: degeneration of the interverterbral disk is as a cause of low-back pain is increasing. to gain insight into relationships between biological processes, structural alterations and behavioral pain, we created an animal model in rats. methods: disk degeneration was induced by removal of the nucleus pulposus (np) from the lumbar disks (l4/l5 and l5/l6) of sprague dawley rats using a 0.5-mm-diameter microsurgical drill. the degree of primary hyperalgesia was assessed by using ...201121996269
microleakage of a self-adhesive resin cement after post cementation.the aim of this study is to evaluate the microleakage a self-adhesive cement recently marketed rely x u100 (3m espe). thirty roots of bovine teeth with 14 mm long were restored with self-adhesive cement and glassix fiber post dc3 (fgm). roots were randomly divided into three groups (n=10) according to the technique of placement of the cementing agent: g1 - centrix syringe; g2 - lentulo drill and g3 - manual technical. after cementation, provisional restorations were fabricated with composite res ...201122010415
Osteoscopy for Assessment of Blood Supply to the Femoral Head: A Preliminary Study.OBJECTIVES:: The aim of our study was to develop a minimally invasive endoscopic procedure (osteoscopy), which is capable of visualizing blood supply and quantitatively assessing circulation to the femoral head at the time of definitive surgery. METHODS:: The new diagnostic technique was developed in animal experiments (four piglets) and was subsequently tested in nine consecutive patients requiring surgery for a femoral neck fracture. The direct visualization of the femoral head circulation was ...201122011637
The dog as a preclinical model to evaluate interface morphology and micro-motion in cemented total knee replacement.Objectives: This study investigated cemented fixation of the tibial component from a canine total knee replacement preclinical model. The objective was to determine the local morphology at the material interfaces (implant, cement, bone) and the local relative micro- motion due to functional loading following in vivo service. Methods: Five skeletally mature research dogs underwent unilateral total knee replacement using a cemented implant system with a polyethylene (PE) monobloc tibial compon ...201122028048
Face and Content Validation of a Virtual Reality Temporal Bone Simulator.Objective. To validate the VOXEL-MAN TempoSurg simulator for temporal bone dissection.Study Design. Prospective international study.Setting. Otolaryngology departments of 2 academic health care institutions in the United Kingdom and United States.Subjects and Methods. Eighty-five subjects were recruited consisting of an experienced and referent group. Participants performed a standardized familiarization session and temporal bone dissection task. Realism, training effectiveness, and global impre ...201122051543
osseointegration of dental implants installed without mechanical engagement: a histometric analysis in dogs.objectives: the purpose of this study was to elucidate the healing pattern of sand-blasted, large grid, acid-etched (sla)-surfaced implants at two healing periods in a model that represents loosened implants (lis) installed without mechanical engagement. material and methods: five mongrel dogs were used, in which 20 dental implants were prepared. the implants were divided into two groups according to the absence or presence of initial mechanical engagement: lis) and control, respectively. an ove ...201122092341
Descriptive study of the longevity of dental implant surgery drills.Background: Atraumatic preparation of the osteotomy site is critical for osseointegration.Purpose: This study aimed to investigate the effects of multiple usages of dental implant drills on bone temperature changes and to examine the cutting surfaces of these drills under a scanning electron microscope (SEM).Materials and Methods: The implant osteotomy procedure was adapted to the experimental setting to simulate wear on implant drills by preparing bovine ribs using a constant drilling force. Th ...201122106473
tai chi () pedicle screw placement for severe scoliosis.study design:: retrospective. objective:: to evaluate the clinical safety and accuracy of the tai chi () technique for placing pedicle screws, without intraoperative radiographic imaging, in severe scoliotic spines. summary of background data:: the current techniques for pedicle screw placement have a number of drawbacks in cases of severe scoliosis, including difficulty or impossibility to use, delayed operative time, requiring the presence of trained personnel for the duration of the surgery, ...201122124422
effect of sequential hole enlargement on cortical bone temperature during drilling of 6.2-mm-diameter transcortical holes in the third metacarpal bones of horse cadavers.to compare the bone temperature and final hole dimensions associated with sequential overdrilling (so) and single 6.2-mm drill bit (s6.2db) methods used to create transcortical holes in the third metacarpal bones (mciiis) of horse cadavers.201122126699
Nerve damage assessment following implant placement in human cadaver jaws - an ex vivo comparative study.Abstract The present study compared the use of Cone Beam Computerized Tomography (CBCT) images and intraoral radiographs in the placement of final implant drills in terms of nerve damage to cadaver mandibles. Twelve cadaver hemimandibles obtained from 6 cadavers were used. Right hemimandibles were imaged using periapical radiography and left hemimandibles using CBCT, and the images obtained were used in treatment planning for the placement of implant drills (22 for each modality, for a total o ...201122150347
evaluation of bone heating, immediate bone cell viability, and wear of high-resistance drills after the creation of implant osteotomies in rabbit tibias.the purpose of this study was to evaluate the influence of reusing high-resistance drills on bone heating, immediate bone cell viability, and drill wear after performing implant osteotomies in rabbit tibias.201122167423
microcomputed tomographic analysis of bone reaction at insertion of orthodontic mini-implants in sheep.to evaluate the effects on bone of forced insertion of self-tapping orthodontic mini-implants and thus obtain biomechanical data to develop insertion protocols and optimize drills for implant site preparation.201122167428
proteinase-activated receptor-2 is required for normal osteoblast and osteoclast differentiation during skeletal growth and repair.proteinase-activated receptor-2 (par(2)) is a g-protein coupled receptor expressed by osteoblasts and monocytes. par(2) is activated by a number of proteinases including coagulation factors and proteinases released by inflammatory cells. the aim of the current study was to investigate the role of par(2) in skeletal growth and repair using wild type (wt) and par(2) knockout (ko) mice. micro computed tomography and histomorphometry were used to examine the structure of tibias isolated from uninjur ...201122173052
myogenic progenitors contribute to open but not closed fracture repair.abstract: background: bone repair is dependent on the presence of osteocompetent progenitors that are able to differentiate and generate new bone. muscle is found in close association with orthopaedic injury, however its capacity to make a cellular contribution to bone repair remains ambiguous. we hypothesized that myogenic cells of the myod-lineage are able to contribute to bone repair. methods: we employed a myod-cre+:z/ap+ conditional reporter mouse in which all cells of the myod-lineage are ...201122192089
material attrition and bone micromorphology after conventional and ultrasonic implant site preparation.objectives: little is known about the recently introduced ultrasonic implant site preparation. the purpose of this study was to compare material attrition and micromorphological changes after ultrasonic and conventional implant site preparations. material and methods: implant site preparations were performed on fresh bovine ribs using one conventional (straumann, freiburg, germany) and two ultrasonic (piezosurgery(®) ; mectron medical technology, carasco, italy and variosurg(®) ; nsk, tochigi, j ...201222248387
arthroscopically assisted retrograde drilling for osteochondritis dissecans (ocd) lesions of the knee.purpose: accurate retrograde drilling for osteochondritis dissecans lesions remains technically challenging. a novel, radiation-free method using an electromagnetic guidance system was developed, and its feasibility and accuracy for retrograde drilling procedures evaluated in an experimental setting. methods: sixteen arthroscopically assisted, electromagnetically guided retrograde drilling procedures were perform ...201222258653
modeling and experimentation of bone drilling forces.prediction and control of bone drilling forces are critical to the success of many orthopaedic operations. uncontrolled and large forces can cause drill-bit breakage, drill breakthrough, excessive heat generation, and mechanical damage to the bone. this paper presents a mechanistic model for prediction of thrust forces and torques experienced during bone drilling. the model incorporates the radially varying drill-bit geometry and cutting conditions analytically, while capturing the material and ...201222281407
development of a femoral stem providing strong anchorage and facilitated removal. an experimental study in goats.prosthetic elements must be securely anchored to bone. should revision surgery be necessary, preservation of bone stock is crucial. the goal of this study was to develop and assess a femoral stem combining secure anchorage and facilitated removal in a goat model.201222286897
gastrointestinal parasites of captive and free-roaming primates at the afi mountain primate conservation area in calabar, nigeria and their zoonotic implications.a study on the gastrointestinal parasites among free-living and captive primates at the afi mountain, primate conservation area in calabar, nigeria was undertaken for the first time to ascertain their zoonotic implications. faecal samples were subjected to direct smear, floatation, quantitative estimation of helminth eggs (epg) and oocysts (opg), larval isolation and identification by modified baerman's technique and oocyst sporulation for specie identification. out of the 108 primates examined, ...201122308652
multi-step adhesive cementation versus one-step adhesive cementation: push-out bond strength between fiber post and root dentin before and after mechanical cycling.this study evaluated the effects of mechanical cycling on resin push-out bond strength to root dentin, using two strategies for fiber post cementation. forty bovine roots were embedded in acrylic resin after root canal preparation using a custom drill of the fiber post system. the fiber posts were cemented into root canals using two different strategies (n = 20): a conventional adhesive approach using a three-step etch-and-rinse adhesive system combined with a conventional resin cement (scotchbo ...201222313828
craniodental features in male mandrillus may signal size and fitness: an allometric approach.according to a hypothesis in the broader mammalian literature, secondary sexual characteristics that have evolved to signal fitness and size to other conspecifics should exhibit positive allometry across adult males within a species. here this hypothesis is tested in the genus mandrillus. the overbuilding of bony features in larger individuals necessitates a functional explanation as bone is metabolically expensive to produce and maintain. canine size and size of the maxillary ridge are scaled a ...201222328467
destruction of raman biosignatures by ionising radiation and the implications for life detection on mars.raman spectroscopy has proven to be a very effective approach for the detection of microorganisms colonising hostile environments on earth. the exomars rover, due for launch in 2018, will carry a raman laser spectrometer to analyse samples of the martian subsurface collected by the probe's 2-m drill in a search for similar biosignatures. the martian surface is unprotected from the flux of cosmic rays, an ionising radiation field that will degrade organic molecules and so diminish and distort the ...201222349404
evaluation of cameroonian plants towards experimental bone regeneration.elephantopus mollis, spilanthes africana, urena lobata, momordica multiflora, asystasia gangetica and brillantaisia ovariensis are used in cameroonian traditional medicine for the treatment of bone diseases and fracture repair. the aim of this study was to evaluate the effect of ethanolic extracts of six cameroonian medicinal plants on bone regeneration following bone and marrow injury.201222414477
influence of the drill material and method of cooling on the development of intrabony temperature during preparation of the site of an implant.our aim was to evaluate the intrabony friction heat produced by implant drills, using different drill materials and methods of cooling. four pilot drills and 4 form drills were used. the following combinations of drill material and cooling supply were tested: steel and external cooling; steel and internal cooling; steel coated with zirconium nitride and external cooling; and zirconium oxide and external cooling. the handpiece that supported the drill was fixed in a lifting device. specimens of b ...201322417718
effect of compound of gelatin hydrogel microsphere incorporated with platelet-rich-plasma and alginate on sole defect in cattle.platelet-rich plasma (prp) was administered to cattle with hoof defects (10-mm drill hole) to promote sole defect healing. two types of gels were prepared. one was a mixed gel [compound of gelatin microspheres (gm) incorporated with prp and alginate] and was used for the test group, while the other was an alginate gel used for the control group. each hole was filled with one of these gels. the drill hole depth, pressure pain, and hardness of the regenerated tissue were measured for 3 weeks after ...201222446403
potential exposure of bees, apis mellifera l., to particulate matter and pesticides derived from seed dressing during maize sowing.this paper assessed the potential exposure of bees (apis mellifera l.) to pesticides during maize (zea mays l.) sowing with pneumatic drills. data were derived from tests carried out in field tests, comparing two configurations of a pneumatic precision drill: conventional drill; drill with air deflectors. in addition, static tests simulating the sowing under controlled conditions, were performed on the drill equipped with an innovative system developed at cra-ing. during the field tests, the con ...201222562269
genetic signatures of a demographic collapse in a large-bodied forest dwelling primate (mandrillus leucophaeus).it is difficult to predict how current climate change will affect wildlife species adapted to a tropical rainforest environment. understanding how population dynamics fluctuated in such species throughout periods of past climatic change can provide insight into this issue. the drill (mandrillus leucophaeus) is a large-bodied rainforest adapted mammal found in west central africa. in the middle of this endangered monkey's geographic range is lake barombi mbo, which has a well-documented palynolog ...201222822434
biomechanical effect of one session of low-level laser on the bone-titanium implant interface.low-level laser (lll) has been used on peri-implant tissues for accelerating bone formation. however, the effect of one session of lll in the strength of bone-implant interface during early healing process remains unclear. the present study aims to evaluate the removal torque of titanium implants irradiated with lll during surgical preparation of implant bed, in comparison to non-irradiation. sixty-four wistar rats were used. half of the animals were included in lll group, while the other half r ...201322825319
ultrasonic measurement of bone thickness for spinal surgery.we measured the thickness of the transverse structures associated with the bovine coccygeal transverse processes (bone specimen) by using ultrasonic waves and examined the reliability of this measurement for use in spinal surgery. we first measured the velocity of ultrasonic waves propagating in the spinous process. we then made a hole in the transverse process with an air drill and placed an ultrasonic transducer with a center frequency of 10 mhz in the hole. the time of reflection of the ultra ...201223007783
thermal effects of a combined irrigation method during implant site drilling. a standardized in vitro study using a bovine rib model.the purpose of this study was to evaluate the temperature changes during implant osteotomies with a combined irrigation system as compared to the commonly used external and internal irrigation under standardized conditions.201423009204
propolis: a new alternative for root canal disinfection.this study evaluated and compared colony forming units (cfus) and minimum inhibitory concentrations (mics) of calcium hydroxide and propolis as intracanal medicaments.201223056131
acute cardiovascular effects of firefighting and active cooling during rehabilitation.to determine the cardiovascular and hemostatic effects of fire suppression and postexposure active cooling.201223090161
comparison of heat generation between internally guided (cannulated) single drill and traditional sequential drilling with and without a drill guide for dental implants.to determine whether a wire-guided single drill protocol could be utilized without causing an increase in bone temperature beyond those seen with the traditional techniques of sequential drilling with and without a drill guide.201223189297
preference alters consumptive effects of predators: top-down effects of a native crab on a system of native and introduced prey.top-down effects of predators in systems depend on the rate at which predators consume prey, and on predator preferences among available prey. in invaded communities, these parameters might be difficult to predict because ecological relationships are typically evolutionarily novel. we examined feeding rates and preferences of a crab native to the pacific northwest, cancer productus, among four prey items: two invasive species of oyster drill (the marine whelks urosalpinx cinerea and ocenebra ino ...201223236472
the role of bone marrow-derived cells during the bone healing process in the gfp mouse bone marrow transplantation model.bone healing is a complex and multistep process in which the origin of the cells participating in bone repair is still unknown. the involvement of bone marrow-derived cells in tissue repair has been the subject of recent studies. in the present study, bone marrow-derived cells in bone healing were traced using the gfp bone marrow transplantation model. bone marrow cells from c57bl/6-tg (cag-egfp) were transplanted into c57bl/6 j wild mice. after transplantation, bone injury was created using a 1 ...201223263655
a novel standardized bone model for thermal evaluation of bone osteotomies with various irrigation methods.based on a novel standardized bovine specimen, the aim of this study was to investigate thermal effects of different irrigation methods during intermittent and graduated drilling.201423347297
root distribution and potential interactions between allelopathic rice, sprangletop (leptochloa spp.), and barnyardgrass (echinochloa crus-galli) based on ¹³c isotope discrimination analysis.weed-suppressive rice cultivars hold promise for improved and more economical weed management in rice. interactions between roots of rice and weeds are thought to be modulated by the weed-suppressive activity of some rice cultivars, but these phenomena are difficult to measure and not well understood. thus, above-ground productivity, weed suppression, and root distribution of 11 rice cultivars and two weed species were evaluated in a drill-seeded, flood-irrigated system at stuttgart, arkansas, u ...201323397455
evaluation of three miniplate systems for fracture stabilization in pigeons (columba livia).bone plates are rarely used in avian fracture management for several reasons, and until recently, there was no plating system considered appropriate for use in birds with a body mass less than 500 g. to evaluate 3 different miniplate systems in avian fracture repair, 3 groups (a, b, and c) of 6 pigeons (columba livia) each were used. the left ulna and radius of the pigeons were transected, and the ulna was stabilized. in group a, a 1.3-mm adaption plate was used. in group b, a limited contact sy ...201223409431
chondrocyte death after drilling and articular screw insertion in a bovine model.intra-articular screws are used for internal fixation of osteochondral fragments after fracture or osteochondritis dissecans. this causes cartilage injury potentially leading to chondrocyte death. we have visualised/quantified the hole and zone of cell death (zcd) in cartilage after drilling/insertion of various articular screws.201323428599
a comparitive clinical study between self tapping and drill free screws as a source of rigid orthodontic anchorage.self-tapping miniscrews are commonly being used as a temporary anchorage device for orthodontic purpose. a prerequisite for the insertion of these screws is the preparation of a pilot hole, which is time consuming and may result in damage to nerves, tooth root, drill bit breakage and thermal necrosis of bone. on the other hand the design of drill-free screws enables them to be inserted without drilling. the aim of this prospective study was to compare the stability and clinical response of the s ...201123449815
a comparison of accuracy between step and non-step reamers of femoral intramedullary alignment system in total knee arthroplasty evaluated by computer-assisted navigation.limb alignment after total knee replacement has been demonstrated to be one of the most influential in determining long-term survival of the implants. malalignment can contribute to early prosthesis failure through point loading and premature polyethelene wear. alignment guides have been developed to improve the accuracy of femoral and tibial cuts during surgery. recently, there are at least two groups of femoral intramedullary reamer. the first group uses step reamer (8 mm drill with 10 mm step ...201223451442
the relationship between muscle strength, anaerobic performance, agility, sprint ability and vertical jump performance in professional basketball players.the purpose of this study was to investigate the relationship between isokinetic knee strength, anaerobic performance, sprinting ability, agility and vertical jump performance in first division basketball players. twelve male first division basketball players participated in this study. the mean age was 25.1 ± 1.7 yrs; mean body height 194.8 ± 5.7 cm; mean body mass 92.3± 9.8 kg; mean pbf 10.1± 5.1; and mean vo2max 50.55 ± 6.7 ml/kg/min quadriceps and hamstrings were measured at 60° and 180°/s, ...201223486566
comparison of a new test for agility and skill in soccer with other agility tests.the purpose of this study was both to develop a novel test to measure run, shuttle run and directional change agility, and soccer shots on goal with decision making and to compare it with other agility tests. multiple comparisons and assessments were conducted, including test-retest, illinois, zig-zag, 30 m, bosco, t-drill agility, and wingate peak power tests. a total of 113 turkish amateur and professional soccer players and tertiary-level students participated in the study. test-retest and in ...201223486732
Displaying items 901 - 1000 of 1107