Publications

mechanisms of malarial immunity.	immunity to malaria in many species, including man, is acquired only after long exposure to infection and is associated with chronic low-grade parasitaemia. vaccination of rhesus monkeys with p. knowlesi merozoites in fca induces sterilizing immunity which is species specific. merozoite-blocking (inhibitory) antibody usually correlates with clinical immunity and protection can be passively transferred with immune sera. however, vaccination using adjuvants other than fca may induce inhibitory ant ...	1977	413215
a critique of merozoite and sporozoite vaccines in malaria.		1977	413340
antigenic variation in malaria.		1977	413343
immunoprophylaxis of malaria: sporozoite-induced immunity.		1977	413344
radical cure of infections with plasmodium cynomolgi: a function of total 8-aminoquinoline dose.		1977	413444
erythrocyte receptors for malaria merozoites.		1977	413448
acquired immunity and vaccination in malaria.		1977	413450
exacerbation of experimental trypanosoma cruzi infection in mice by concomitant malaria.	the effect of malaria on the chronic phase of chagas' disease was investigated in mice. the animals were given plasmodium bergheri-infected red blood cells 2 to 12 months after their initial inoculation with trypomastigotes of 3 different strains of trypanosoma cruzi (y. cl and gilmar). in all the experiments carried out with one of the strains (cl), a somewhat variable but always considerable percentage of mice (average 39%) relapsed in to the acute phase of chagas' disease. this relapse was ch ...	1977	413912
[light microscopic and scanning electron microscopic observations on phagocytosis of plasmodium berghei infected erythrocytes by mouse macrophages [author's transl)].	peritoneal macrophages from mice were cultured in leighton tubes for 2 hours. thereafter suspensions of washed red blood corpuscles originating from plasmodium berghei-infected mice were offered to the cultured cells for phagocytosis. after 15 minutes of incubation 13,5% of the macrophages showed phagocytized parasites if the peritoneal cells came from malariaimmune mice. cells from normal mice or from infected mice had lower rates (4,8/9,1%). after an incubation of 3 hours about 50% of the cell ...	1977	414386
antibody mediated mechanisms of immunity to malaria induced by vaccination with plasmodium knowlesi merozoites.	rhesus monkeys vaccinated with merozoites in fca are protected against challenge with several strains and variants of plasmodium knowlesi. vaccination induces sterilizing immunity which is species specific. merozoite-blocking (inhibitory) antibody usually correlates with clinical immunity and protection can be passively transferred with immune sera provided these contain high levels of inhibitory antibody. however, vaccination using adjuvants other than fca may induce inhibitory antibody without ...	1978	414993
in vitro cultivation and partial purification of plasmodium falciparum antigen suitable for vaccination studies in aotus monkeys.		1978	415127
plasmodium knowlesi malaria in the rhesus monkey.	twelve rhesus monkeys were inoculated intravenously with about 500 000 malaria parasites, plasmodium knowlesi. acute hemolysis occurred 5 days later, and all animals died on the 6th or 7th day after inoculation. all organs were gray-green to gray-brown because of deposition of hemoglobin and malaria pigments. this deposition was particularly striking in the lung, brain, abdominal fat and serous surfaces. microscopic changes indicative of acute hypoxia were found in the liver (centrilobular necro ...	1978	415405
selection of increased quinine resistance in plasmodium falciparum in aotus monkeys.	although partial resistance (ri) of plasmodium falciparum to quinine is common in some areas of the world, failure to obtain an initial response (rii or riii) is unusual. furthermore, emergence of quinine resistance during therapy of malaria infections in humans and animals is uncommon. in the current study, exposure of the panama ii strain of p. falciparum in aotus monkeys to subcurative quinine therapy during six serial passages over 6 months resulted in a shift in the quinine responsiveness o ...	1978	415628
the significance of plasma kinins in malaria.		1978	416663
host defenses in murine malaria: evaluation of the mechanisms of immunity to plasmodium yoelii infection.	the immune response of random-bred mice to infection with a relatively avirulent strain of plasmodium yoelii was measured in terms of parasitemia, splenomegaly, immediate and delayed hypersensitivity to a p. yoelii antigen preparation, resistance to challenge with a virulent variant of p. yoelii, and nonspecific resistance to l. monocytogenes. avirulent p. yoelii produced a self limiting infection which resolved in 21 days. peak parasitemia and splenomegaly were observed at 14 days, and infected ...	1979	422246
[interesting items of tropical medicine (author's transl)].		1979	432211
free-flow electrophoresis for the separation of malaria infected and uninfected mouse erythrocytes and for the isolation of free parasites (plasmodium vinckei): a new rapid technique for the liberation of malaria parasites from their host cells.	after aggregation of erythrocytes from malaria infected mice, the parasites (plasmodium vinckei) could be set free using gentle mechanical forces. the mixture of freed parasites, infected and non-infected erythrocytes, and membraneous material was separated by free-flow electrophoresis. the free parasites produced were very pure and infectious. morphological and enzymatic data on the separated fractions are presented. free-flow electrophoresis also allowed the separation of infected and uninfect ...	1979	433382
fluctuations in proline and other free amino acids during the mitotic cycle of the myxomycete physarum polycephalum.	1. during synchronous growth of the acellular slime mould physarum polycephalum the free amino pool had two maxima, one of 650 units [nmol/plasmodium dry weight (mg)] at metaphase and the other of 780 units in mid g2 with minima of 550 units before and after mitosis. 2. proline formed 20--25% of the total pool with aspartic acid, glutamic acid, threonine, valine, leucine, lysine and arginine making up 55% of the pool. 3. the fluctuation of proline during the mitotic cycle was quite different fro ...	1979	436826
plasmodium gallinaceum: transmission-blocking immunity in chickens. i. comparative immunogenicity of gametocyte- and gamete-containing preparations.		1979	437016
immunobiology of malaria.	malaria, the number one disease in the world, is caused by intracellular protozoans belonging to the subphylum, sporozoa; suborder, haemosphoridia; and family, plasmodiidae. the four classical organisms producing disease in man are plasmodium vivax, p. falciparum, p. malariae, and p. ovale. although malaria has been known to man for centuries, attempts are still being made to control and eliminate its devastating effects in tropical and subtropical areas of the world. current active interest in ...	1979	439167
defective resistance to plasmodium yoelii in cba/n mice.	the role of b lymphocytes in resistance to malaria was studied in defective and normal f1 mice derived from cba/n mice, a strain with an x-linked b cell defect. when infected with normally nonlethal plasmodium yoelii, immune defective f1 male mice had higher parasitemias and more prolonged infections than normal f1 mice, as well as a 50% mortality rate. before infection the plasma levels of igm and igg were lower in defective f1 males than normal f1 mice. the polyclonal igm and igg responses of ...	1979	448143
immune phagocytosis in murine malaria.	spleen macrophages from plasmodium berghei-infected mice are more efficient in the ingestion of parasitized reticulocytes than spleen macrophages obtained from normal animals. other indications of spleen macrophage activation detected during malarial infection are enhanced macrophage spreading and increased phagocytosis of opsonized and nonopsonized sheep erythrocytes (e). peritoneal macrophages are not activated to a significant degree. the appearance of antibodies directed against forssman ant ...	1979	448288
maloprim prophylaxis: inadequate plasmodium vivax cover.		1979	449823
plasmodium lophurae: composition and properties of hemozoin, the malarial pigment.		1979	456467
influence of malaria infection on the elaboration of soluble mediators by adherent mononuclear cells.	malaria results in two seemingly paradoxical perturbations of the immune response: polyclonal b-cell activation and immunosuppression. to determine what immunoregulatory role mediators secreted by adherent cells might play in these alterations, we cultured adherent cells from uninfected mice and from mice at different times during infection with plasmodium berghei or p. yoelii. culture supernatants obtained from these cells were tested for their ability to enhance the in vitro proliferative resp ...	1979	457269
malaria and erythrocyte glucose-6-phosphate dehydrogenase variants in west africa.	in a clinical study, 702 nigerian children aged 1-6 years were examined for malaria. comparison of morbidity rates and parasitemia of patients with different glucose-6-phosphate dehydrogenase (g6pd) status provided evidence that in heterozygous females the gene for g6pd deficiency (gda-/gdb) confers an advantage against malaria.	1979	464185
crystallization and preliminary crystallographic data of chicken gizzard g-actin . dnase i complex and physarum g-actin . dnase i complex.	smooth muscle g-actin from chicken gizzard and physarum plasmodium g-actin both interact with dnase i and form 1 : 1 complexes. these complexes were crystallized by using polyethylene glycol 6000 as a precipitant. both crystals belong to the same orthorhombic space group p2(1)2(1)2(1). the cell dimensions of chicken gizzard g-actin.dnase i complex are a=42.00 +/- 0.07 a, b=225.3 +/- 0.4 a, and c=77.4 +/- 0.1 a, while those of physarum g-actin.dnase i complex are a=42 a, b=221 a, and c=77 a.	1979	479124
a malarial parasite of australian skinks, plasmodium mackerrasae sp. n.	plasmodium mackerrasae sp. n. parasitizes the australian lizards egernia cunninghami and e. striolata (sauria: scincidae). described from an experimental host, e. whitei, it produces mature schizonts containing 6--12 nuclei arranged peripherally as a rosette, and round to oval gametocytes which are equal to or slightly smaller than host cell nuclei. both schizonts and gametocytes parasitize all cells in the erythrocyte series. presence of pigment in both asexual and sexual stages is correlated w ...	1979	480071
antibody to fibrinogen/fibrin products (anti-f) in malaria, babesiosis, and trypanosomiasis of rodents.	antibody to fibrinogen/fibrin related products (anti-f) was stimulated during the course of plasmodium chabaudi, babesia rodhaini, and trypanosoma lewisi infections in rats. titers of this autoantibody remained elevated in serum from rats that had recovered from each of the infections. column chromatographic studies indicated that anti-f was a 19s globulin, possibly igm. during acute infections high titers of anti-f were associated with elevated titers of cold-active hemagglutinin (cah) and immu ...	1979	480072
[genetic differentiation of mosquitoes, and malaria].		1979	483823
[plasmodium chabaudi: changes in the surface sialic acids of red blood cells during infection (author's transl)].	surface sialic acids of mice red blood cells infected with the malarial parasite plasmodium chabaudi are increased as compared to extracts of red cells from normal mice. this increase occurs coincidentally when reticulocytes increase in the peripheral blood. the same increase of surface sialic acids is shown by studies of reticulocytes from phenylhydrazine treated mice. similarly, neutral hexoses, fucose, were found in greater quantities in surface glycopeptides obtained after incubation with tr ...	1979	485035
abnormal haemoglobins in the sudan savanna of nigeria. iv. malaria, immunoglobulins and antimalarial antibodies in haemoglobin ac individuals.	haemoglobin (hb) ac electrophoretic pattern was found in 0.7% of the population at garki, kano state, northern nigeria, an area where malaria is hyperendemic. twenty-one hb.ac subjects at all ages did not differ from the rest of the population in their frequency or density of plasmodium falciparum, p. malaria or p. ovale infections, nor in their igm concentrations and titres of specific antimalarial antibodies. however, igg levels in hb.ac subjects were frequently above the average of the refere ...	1979	496483
a pocket of controlled malaria in a holoendemic region of west africa.	yekepa, a mining town in northern liberia, has been built entirely since 1960 and now has a population of 16 000 inhabitants including 1500 expatriates. although situated in a holoendemic region with constant human movements in and out of the town, the mining company has succeeded in controlling malaria in yekepa. furthermore, there is a constant threat of the vector in the close surroundings to the town. control is maintained by regular residual insecticide sprayings with ddt, regular larvicidi ...	1979	496484
habits of malaria chemoprophylaxis and an analysis of breakdowns in a west african mining town.	in a west african community approximately 80% of the non-african personnel were taking malaria prophylactics in the recommended manner. the non-takers stated that they were afraid of side-effects of the drugs and/or under-estimated the risks of the disease. during one year 123 patients with clinically suspected malaria were studied. all patients with positive slides were cured with regular dose of 1.5 g chloroquine base. no chloroquine resistance was therefore demonstrated, although 4-aminoquino ...	1979	496485
malaria--an american problem.		1979	500272
a serological survey of malaria in a rural community near delhi.		1979	521090
avian malaria in african black-footed penguins.	ten captive-reared african black-footed penguins (spheniscus demersus) from a large outdoor colony were monitored for avian malaria, using several diagnostic tests. one treatment regimen was evaluated. thin smear blood evaluation enabled detection of seven parasitemias involving plasmodium relictum and plasmodium elongatum in the penguins. leukocytosis (relative lymphocytosis) was characteristic of infected birds. parasitemia was detected as early as 21 days prior to onset of clinical signs (dep ...	1979	521378
serologic survey for toxoplasma gondii in wild animals in florida.	blood samples were collected for serum separation from 114 species of wild animals (25 species of mammals, 82 species of birds, and 7 species of reptiles) in florida. each of the 3,471 samples was tested for antibodies to toxoplasma gondii, using the indirect hemagglutination test. the highest prevalences of t gondii antibodies were 19% in armadillos (dasypus novemcinctus), 18% in raccoons (procyon lotor), 13% in black rats (rattus rattus), and 11% in opossums (didelphis marsupialis). antibody p ...	1979	521384
avian malaria parasites.		1979	529350
a taxonomic revision of small neotropical saurian malarias allied to plasmodium minasense.	saurian malaria species which produce schizonts smaller than normal erythrocyte nuclei, with 4-8 merozoietes and gametocytes equal to or smaller than erythrocyte nuclei in size, parasitizing hosts of the lizard families scincidae, iguanidae and teiidae in the neotropics are considered to be plasmodium minasense carini and rudolph, 1912. subspecific designations are given to distinctive populations parasitizing different host species: p. minasense minasense is recognized from the type host, mabuy ...	1979	533109
determination of hypoxanthine, xanthine, and uric acid in biological fluids by ion-pair high-performance liquid chromatography.		1979	536443
plasmodium lophurae: membrane proteins of erythrocyte-free plasmodia and malaria-infected red cells.	plasma membranes of normal duckling erythrocytes were prepared by blender homogenization and nitro-en decompression. surface membrane vesicles of red cells infected with the avian malaria plasmodium lophurae were produced by nitrogen decompression. membranes of erythrocyte-free malaria parasites were removed from cytoplasmic constituents by dounce homogenization. these membranes were collected by centrifugation in a sucrose step gradient and purified on a linear sucrose gradient. red cell membra ...	1979	536938
separation of erythrocytes infected with murine malaria parasites in metrizamide gradients.	density gradients with metrizamide, a tri-iodinated benzamido derivative of glucose, have been used to separate erythrocytes infected with 3 species of murine plasmodia. good separations were obtained of uninfected erythrocytes from erythrocytes containing parasites in different developmental stages. with metrizamide solutions, the densities required for isopyenic separation can be obtained without hypertonicity or high viscosity, and the viability and those aspects of the metabolism of parasite ...	1979	537838
a taxonomic reconsideration of some plasmodium species from iguanid lizards.	saurian plasmodium populations previously identified as p. tropiduri from panama are described as subspecies or distinct species. the nominate subspecies, p. tropiduri tropiduri parasitizes tropidurus species from brazil, guyana and venezuela. two other subspecies occur in panama, p. tropiduri panamense from anolis biporcatus and p. tropiduri aquaticum from the semi-aquatic lizards anolis lionotus and a. poecilopus. parasites found in anolis frenatus are described as a distinct species, p. margi ...	1979	539715
[study of gametocytes from the plasmodium "vivax" group: morphology, development in anopheles and infectivity of plasmodium yoelii microgametocytes].	the study of the gametocytes of plasmodium yoelii enabled the differentiation of 4 morphological types: o, i, ii and iii (in a chronological order) and amongst each of these types the differentiation of healthy and altered gametocytes. these morphological data represent a tool for investigations on the biology of the gametocytes of the "vivax" group. preliminary experiments bring informations on the evolution of gametocytes and the mechanisms of their infectivity. 1--in experimentaly infected wh ...	1979	539716
purification of plasmodium lophurae exoerythrocytic merozoites by an ion exchange column.	exoerythrocytic merozoites of plasmodium lophurae grown in embryonic turkey brain cells were successfully separated from host cell material by elution from a deae-cellulose column at ionic strength 0.22. purity of parasite samples was assessed by sodium dodecyl sulphate acrylamide gel electrophoresis and electron microscopy. increasing the ionic strength gave greater recoveries of merozoites, but host cell contamination increased.	1979	544801
accelerated clearance of uninfected red cells from plasmodium berghei-infected mouse blood in normal mice.	51cr-labelled uninfected cells, separated from plasmodium berghei-infected mouse blood using the fluorescence-activated cell sorter, were cleared more rapidly than normal mouse erythrocytes after intravenous injection into normal mice.	1979	548017
spectral analysis of fluorescence of 8-anilino-1-naphthalenesulfonate in chemoreception with a white plasmodium of physarum polycephalum. evidence for conformational change in chemoreceptive membrane.		1979	549637
[epidemiologic study of malaria in a section of transamazon highway, brazil].		1979	550286
immunisation against gametes and asexual erythrocytic stages of a rodent malaria parasite.		1979	551260
observations on the member species of the anopheles gambiae complex in the gambia, west africa.		1979	555076
plasmodium gallinaceum: transmission-blocking immunity in chickens. ii. the effect of antigamete antibodies in vitro and in vivo and their elaboration during infection.		1979	556175
laser light-scattering analysis of protoplasmic streaming in the slime mold physarum polycephalum.	laser light scattering is shown to be an effective means of obtaining a rapid, objective assessment of dynamic changes in the intact plasmodium of the myxomycete physarum polycephalum during bidirectional (shuttle) streaming. the motion of material in a 100 mum diameter region of a plasmodial vein was studied by following changes in the autocorrelation function of the fluctuations in the scattered light intensity. the autocorrelation function was recorded at 10 s intervals and analyzed to follow ...	1977	556960
[on the problem of histochemical demonstration of esterase activity by the thiolacetic acid method in the acellular slime mold physarum confertum (author's translation)].	the application of the histochemical thiolacetic acid method on plasmodia of the acellular slime mold physarum confertum leads to the formation of lead sulfide deposits at the outer cytoplasmic surface and its invaginations. the reaction cannot be reduced by esterase- and cholin/acetylcholinesterase inhibitors. successive application of lead and sulfide in the absence of substrate results in a lead sulfide deposit at the same sites indicating that the underlying reaction is based on an artificia ...	1977	557162
a mutation (gad) linked to mt and affecting asexual plasmodium formation in physarum polycephalum.	amoebae of the acellular slime mold physarum polycephalum convert to plasmodia both asexually and sexually. genetic analysis of a mutant that exhibits enhanced asexual plasmodium formation is reported. the mutant carries a single lesion (gad-11) located 12.3 map units from mt, a gene that controls mating specificity in sexual plasmodium formation. the mutation, which was isolated in an mt3 strain, is also expressed in mth and mt4 strains.	1977	559671
viability of physarum polycephalum spores and ploidy of plasmodial nuclei.	amoebae of physarum polycephalum carrying the mth mating-type allele may differentiate into plasmodia in the absence of mating. such plasmodia are haploid and, upon sporulation, produce mainly inviable spores. we have asked whether the viable spores arise from meiotic or mitotic divisions. using a microfluorometric measurement of the deoxyribonucleic acid content of individual nuclei, we found the fraction of viable spores to be correlated with the proportion of rare, diploid nuclei containing i ...	1977	560366
effect of sugars on salt reception in true slime mold physarum polycephalum. physicochemical interpretation of interaction between salt and sugar receptions.	interaction between salt and sugar receptions in plasmodium of physarum polycephalum was studied by using double-chamber method. effect of sugars on salt reception was evaluated by measuring membrane potential and the motive force of tactic movement of the slime mold, where salt concentration in one compartment was increased successively with a fixed sugar concentration. results are summarized as follows: (1) the presence of d-glucose, d-mannose, d-maltose, or sucrose in medium led to increase o ...	1977	560489
nuclear dna content and chromosome numbers throughout the life cycle of the colonia strain of the myxomycete, physarum polycephalum.	nuclear dna content and ploidy have been determined at different stages of the life cycle of the colonia strain of the myxomycete physarum polycephalum. analyses at the plasmodial stage showed that (a) burton and fuelgen dna analyses agreed within 15% with strains which ranged from 0-6 to 3-6 pg of dna per nucleus; (b) s-phase in colonia is during the early part of interphase as in the wisconsin strain; (c) in heterothallic and heterothallic x colonia crossed strains there are 1-0-1-2 pg of dna ...	1977	561091
synchrony in the rhythm of the contraction-relaxation cycle in two plasmodial strands of physarum polycephalum.	rhythmicity of contraction of plasmodial strands of physarum polycephalum was studied, by measuring the isometric tension exerted by isolated segments of the strands. when 2 strands were connected by way of a plasmodial mass, the contraction-relaxation cycle of the 2 strands synchronized. such cycle activity of the strand was found to be well coordinated with shuttle streaming in the plasmodial mass which had been in connection with the strand. the presence of a control system which induces sync ...	1977	562892
histidine-rich protein as a model malaria vaccine.	ducklings were successfully immunized against plasmodium lophurae with a purified and characterized histidine-rich protein as antigen. the use of adjuvant is not required for this protective effect, and immunity can be passively transferred with serum.	1978	567375
cyclic production of tension force in the plasmodial strand of physarum polycephalum and its relation to microfilament morphology.	cyclic contraction and relaxation of plasmodial strands of physarum polycephalum were measured under both isotonic and isometric conditions, and their relation to changes in microfilament (mf) morphology was investigated. the contraction-relaxation rhythm of a strand segment was insignificant and irregular immediately after isolation from the mother plasmodium. it became regular half an hour later when local minute rhythms were synchronized spontaneously. if a strand kept under isotonic conditio ...	1978	569161
[chloroquine enantiomers. activity against p. vinckei and binding on dna (author's transl)].	(+)-chloroquine is more active against p. vinckei than (-)-chloroquine. no correlation has been observed between antiplasmodial activity and dna-binding of the chloroquine enantiomers.	1979	582111
malaria in nottingham children.	in five and a half years 16 children were admitted to hospital in nottingham suffering from malaria. thirteen cases were caused by plasmodium vivax and two by p falciparum, and in one the type was not identified. all were children of immigrant parents, predominantly from pakistan, although most were born in england but had been visiting asia. three children were ill on or soon after arrival, but in the others the onset of symptoms was delayed by up to nine months. all made an uneventful recovery ...	1977	589173
experimental infection with plasmodium chabaudi in rats: antigen and antibody associated with anemia and glomerulonephritis of acute infection.	rat-adapted plasmodium chabaudi caused a syndrome characterized by hemolytic anemia, splenomegaly, and glomerulonephritis. all rats recovered and appeared normal after 4 weeks despite persistence of proteinuria. serologic studies on the malarious rats revealed that the infection was associated with a soluble antigen which was present concurrently with antibody in plasma, in material eluted from blood cells, in extracts of kidney tissues, and in the urine. this antigen appeared to be identical wi ...	1977	592039
structural aspects of plasmodium relevant to vaccination against malaria.	the extracellular stages of plasmodium which can be inactivated with antibodies include the sporozoites, merozoites and microgametes. the surface of sporozoites and merozoites are known to bind antibodies which render them unable to invade host cells. intra-erythrocytic merozoites, trophozoites and schizonts release antigens which are conveyed to the surface of the host cell, although they do not appear to be attacked by antibodies directly. the significance of these observations is discussed.	1977	595077
malarial antibodies in tropical splenomegaly syndrome in papua new guinea.	levels of species and class-specific malarial antibody were studied in 249 new guineans with tropical splenomegaly syndrome (tss) and in 87 control subjects living in the same area. titres of igg and igm antibody to plasmodium falciparum, p. vivax and p. malariae were estimated by indirect immunofluorescence. both ig and igm antibody levels were higher in subjects with tss than in controls; igm titres were highest in those with the greatest splenic enlargement. responses to all three species wer ...	1977	595079
immunization against erythrocytic forms of malaria parasites.		1977	596300
plasmodium berghei: relationship between mitosis and erythropoiesis in spleen cells of infected rats.		1977	598448
octadecenoic fatty acids and their association with hemolysis in malaria.	octadecenoic fatty acids have been implicated in prehemolytic and hemolytic phenomena associated with malaria. oleic [18:1 (n-9)] and cis-vaccenic [18:1 (n-7)] acids were found and quantified in the major neutral and phospholipids of the erythrocytes and plasmas of normal and plasmodium lophurae-infected ducks, and in the parasite itself. the octadecenoic fatty acids were elevated over normal values in the major phospholipid classes of infected erythrocytes, in the erythrocyte-specific alkoxy ph ...	1977	599503
[new findings concerning the susceptibility of mosquitoes of the genus anopheles in the ussr to imported strains of the agents of human malaria].		1977	604750
antigenic change in plasmodium knowlesi.		1977	605469
the bionomics and relative prevalence of anopheles species with respect to the transmission of plasmodium to man in western ethiopia.		1977	606817
intestinal and blood parasites in the banggai kabupaten, central sulawesi, indonesia.	a survey for blood and intestinal parasites was carried out in the banggai kabupaten central sulawesi, indonesia. a total of 336, stool specimens were obtained from 182 males and 154 females ranging in age from 2 to 90 years. hookworm, trichuris trichiura and ascaris lumbricoides were the most common helminths encountered. schistosoma japonicum was noticeably absent in the population sampled. the following intestingl protozoa were detected: entamoeba coli, e.histolytica, iodamoeba bütschlii, gia ...	1977	607427
parasites of man in remote areas of central and south sulawesi, indonesia.	a biomedical survey was conducted in 10 villages in remote, high mountain valleys of central and south sulawesi, indonesia to learn whether oriental schistosomiasis was endemic and to determine the prevalences of other intestinal parasites, malaria and filariasis in those areas. although persons with oriental schistosomiasis were found in three villages of south sulawesi, follow-up inquiries revealed that these had recently migrated from a known schistosomiasis area in central sulawesi. other in ...	1977	607428
immunosuppression in murine malaria. ii. the primary response to bovine serum albumin.	the primary antibody response to alumadsorbed bovine serum albumin was depressed in cba mice infected with plasmodium yoelii yoelii. responses initiated within approximately 3 weeks of this malaria infection were reduced in quantity, but not in avidity. responses initated later were normal. a depressed primary response was also seen in infected compared to control splenectomized mice; this was accompanied by impaired priming for a secondary response.	1977	608688
haemoproteus, plasmodium, and hippoboscid ectoparasites of colombian wild doves.		1977	613435
heterologous immunity between piroplasms and malaria parasites: the simultaneous elimination of plasmodium vinckei and babesia microti from the blood of doubly infected mice.	mice which have recovered from infections with the avirulent piroplasm babesia microti are also resistant to challenge with the virulent malaria parasite plasmodium vinckei. in mice infected with p. vinckei before the peak of the b. microti infection the numbers of malaria parasites in the blood increase until that peak and are then eliminated at the same time as the piroplasms. in mice infected with p. vinckei at or after the peak there is no apparent multiplication and the malaria parasites be ...	1978	622306
blood parasites of some birds from senegal.	a total of 809 birds from senegal, including 43 species and 21 families, were examined for hematozoans; 93 birds (11.5%) harbored blood parasites, with only 7 (7.5%) harboring mixed infections. species of haemoproteus occurred in 81.7% of the infected birds while species of plasmodium. trypanosoma, microfilaria and leucocytozoon were encountered less frequently. the majority of the sample was composed of species of ploceids and estrildidis and blood parasites were most prevalent in the colonial- ...	1978	633519
study of coinciding foci of malaria and leptospirosis in the peruvian amazon area.	a hyperendemic malaria focus, found in 1973 in a secluded valley in south-eastern peru, was restudied in 1975. tests for antibodies to plasmodium and leptospira were performed on blood serum and blood slides collected at three locations on the rio ene and confluent streams and at two locations in the neighbouring highlands. the hyperendemic focus of p. vivax-p. malariae found at mission cutivirini in 1973 was confirmed in this study. another hyperendemic focus of predominantly p. vivax was found ...	1978	635982
plasmodium pessoai sp. n. from two costa rican snakes.	a unique malaria parasite species was found in 1/1 spilotes pullatus (colubridae) and 1/70 lachesis muta (crotalidae) from the moist atlantic lowland forests of eastern costa rica. it is distinguished by small, sausage-shaped gametocytes (x 10.4 by 4.6 mu), growing schizonts that often contain a noticeable digestive vacuole with the contents partially visible, and striking spherical or bouquet-shaped segmenters whose precise merozoite numbers are difficult to discern (about 22-32) because of an ...	1978	641676
antimalarial activity of saccharidic polymers of dapsone and sulfadimethoxine.	with the purpose of obtaining pro-drugs of dapsone and sulfadimethoxine, those chemotherapeutic agents were attached through covalent bonding to starch polymeric dialdehyde (sumstar-190). the antimalarial activity of the two resulting compounds - the dapsone saccharidic polymer (ps6) and the sulfadimethoxine saccharidic polymer (ps7) - in mice experimentally inoculated with plasmodium berghei was significantly increased with this molecular modification. mice infected with malaria and kept withou ...	1978	648235
plasmodium iophurae: cationized ferritin staining, an electron microscope cytochemical method for differentiating malarial parasite and host cell membranes.		1978	658214
saurian malaria in texas.		1978	660388
plasmodium durae herman from the introduced common peafowl in northern nigeria.	plasmodium (giovannolaia) durae herman was originally described from kenya, the type host being the common turkey, meleagris gallopavo linnaeus. there are no field records of this association outside of africa, where the parasite, herein reported from another introduced and domesticated bird (the common peafowl, pavo cristatus linnaeus), was recently listed from 2 native phasianidae of the genus francolinus. the justification for the present identification is submitted against background data co ...	1978	660569
comparative study of ultrastructure of interlamellar and intralamellar types of henneguya exilis kudo from channel catfish.	the inter- and intralamellar types of henneguya exilis kudo (myxosporida) infections from channel catfish are similar in spore structure and sporogenesis, but differ in the structure of their plasmodium wall and surface coat and in their relationship with the host cells. the 2 clinical types differ also in the sites of development and growth patterns of plasmodia within a gill filament. interlamellar plasmodia are limited by 2 outer unit membranes which give rise to both single-and double-membra ...	1978	660571
lower azure b methylene blue ratios in giemsa type blood and malaria stains.	starting from ancient reports that rare samples of methylene blue were apparently sufficiently contaminated with azures to give red plasmodial and red purple nuclear chromatin in chenzinsky type methylene blue eosin stains, it was decided to determine how little azure b would suffice for such staining in methylene blue eosin stains. the traditional 1902 giemsa had an azure : methylene blue : eosin ratio of about 6 : 3 : 6.3 : 10; lillie's 1943 formula had a 5 : 7 : 10 ratio. in the current serie ...	1978	663946
splenomegaly, enhanced phagocytosis, and anemia are thymus-dependent responses to malaria.	immunologically competent mice and mice with defined immunological deficiencies were infected with plasmodium yoelii. splenomegaly, enhanced phagocytosis, and anemia were most marked in infected mice having intact thymic tissue. whereas the spleens of infected nude mice increased minimally in size, the relative blood hemoglobin levels and the rates of carbon clearance in these mice were similar to those of noninfected, immunologically intact mice. thymus-reconstituted nude mice and b-cell-defici ...	1978	669820
[cytological diagnosis of malaria with a concentration of parasitized erythrocytes].		1978	673676
a quick and easy method to determine the sporozoite index in mosquitoes.		1978	675790
hemoglobin a2 levels in malaria patients.	the influence of malaria on the hemoglobin a2 (hb a2) level in humans was studied in a series of 94 imported cases in belgium. sixty-nine of the patients were natives of western european countries, their results are reported separately since their origin and the results of their hematological examination made it unlikely that they carried the beta-thalassemia trait. the hb a2 level of the 94 malaria patients (mean 2.76%; s.d. 0.51%) was not statistically different from that found in 60 healthy c ...	1978	686238
effects of cytochalasin a on the morphology of plasmodia and sclerotia of physarum polycephalum.	cytochalasin a (ca) at 1.6 x 10(-5)m and lower concentrations produced disruptive effects upon plasmodia, sclerotia, and spherule forms of physarum polycephalum. ca effects upon either micro- or macroplasmodia included: cytoplasmic condensation, plasmodial contraction, and scission at the plasma membrane. the latter manifestation was most dramatically observed by scanning electron microscopy. electron microscopy of drug-treated palsmodia confirmed the above phase contrast light-microscopic resul ...	1978	689245
plasmodium of physarum polycephalum as a synchronous contractile system.	the contractile activity of veins and the rhythmicity of the frontal progress were photometrically recorded from cine-film, at numerous points across the whole plasmodium. graphic analysis of the obtained curves demonstrates the existence of common contraction rhythm over the entire network, coincident to the expansion rhythm of the advancing front. it is suggested that the plasmodium of physarum polycephalum represents an imperfectly synchronized monorhythmic contractile system.	1978	689260
[description of p. cyclopsi n. sp. a parasite of the microchiropteran bat hipposideros cyclops in gabon (author's transl)].	p. cyclopsi sp. nov. is characterized by the small size of the asexual stages and by gametocytes belonging to the type "malariae". it is related to p. anomaluri and the hosts of both species share the same habitat: hollow trees of the tropical forest. by the ancientness of its vertebrate host and its relationship with the "malariae" group of haemosporidia p. cyclopsi is interpreted as a primitive species.	1978	697287
the incidence of plasmodium parasites in rural zambia.		1978	699838
exacerbation of murine malaria by concurrent infection with lactic dehydrogenase-elevating virus.	the simultaneous infection of mice with lactic dehydrogenase-elevating virus (ldv) and plasmodium yoelii resulted in an exacerbated attack of malaria. peak parasitaemia was higher and the patent infection more prolonged in doubly infected mice. the results indicate that contamination with ldv must be considered when a change in parasite virulence is observed, particularly when the parasite is maintained by blood passage in mice.	1978	719954
aedes fluviatilis (lutz), a new experimental host for plasmodium gallinaceum brumpt.		1978	722461
[homozygotic drépanocytemia (author's transl)].	a clinical description according to four age groups: before 5 with hand and foot syndrome, hemolytic chronic and sometimes acute anemia; after 5 with frequent surgical-like abdominal syndromes and development troubles; after puberty with patent dystrophia and anemia; adult age group of rare surviving patients. the drepanocytic condition is aggravated by various infections and reversly facilitate lung infections and osteitis caused by staphylococci or salmonellae. malaria trophozoïte is suspected ...	1978	723559
[anti-plasmodial antibodies : indicators of parasitic infestation or of antimalarial immunity?].		1978	724491
babesia rodhaini: passive protection of mice with immune serum.	immune serum delayed the onset of parasitemia in both intact and splenectomized mice, but it neither prevented the development of babesia rodhaini infection nor protected the mice from death even with further supplementation of immune serum during the infection. the protective antibodies in the serum are more effective in their action on free b. rodhaini parasites than on infected erythrocytes; the parasites (free or inside the red cells) being direct targets for the antibodies. passive administ ...	1978	726044
increase in non-specific antibody mediated cytotoxicity in malarious mice.	the k cell activity in the spleens of mice infected with plasmodium chabaudi has been investigated. chicken red cells coated with antibody were the target cells used. increased k cell activity was found 6 to 15 days, but not 3 days, after infection with the malaria parasites.	1978	737899