Publications
Title | Abstract | Year Filter | PMID(sorted ascending) Filter |
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continuous cultivations of a penicillium chrysogenum strain expressing the expandase gene from streptomyces clavuligerus: kinetics of adipoyl-7-aminodeacetoxycephalosporanic acid and byproduct formations. | the production kinetics of a transformed strain of penicillium chrysogenum expressing the expandase gene from streptomyces clavuligerus was investigated in chemostat cultivations. the recombinant strain produces adipoyl-7-aminodeacetoxycephalosporanic acid (ad-7-adca) as the major product; however, during the cultivations, the appearance of a major unknown and poorly secreted product was observed. investigations using high-performance liquid chromatography (hplc) and liquid chromatography-mass s ... | 2003 | 12783491 |
continuous cultivations of a penicillium chrysogenum strain expressing the expandase gene from streptomyces clavuligerus: growth yields and morphological characterization. | the growth stoichiometry of a penicillium chrysogenum strain expressing the expandase gene from streptomyces clavuligerus was determined in glucose-limited chemostat cultivations using a chemically defined medium. this strain produces adipoyl-7-aminodeacetoxycephalosporanic acid (ad-7-adca) when it is fed with adipic acid. the biomass yield and maintenance coefficients for the strain were similar to those found for penicillin-producing strains of penicillium chrysogenum. the maximum specific gro ... | 2003 | 12783492 |
autolysis and ageing of penicillium chrysogenum under carbon starvation: respiration and glucose oxidase production. | during the exponential growth phase of penicillium chrysogenum ncaim 00237 the effective conversion of glucose and o2 to gluconate and h2o2 by glucose oxidase (gox) was the most likely source of intracellular ros measured. in glucose-supplemented autolysing cultures, the increased of intracellular ros concentration was attributed to respiration in the absence of any significant gox activity. the induction of gox and catalase by glucose and h2o2 was clearly age-dependent in p. chrysogenum. in age ... | 2003 | 12793202 |
sensitisation to aspergillus fumigatus and penicillium notatum in laboratory workers. | four workers in medical research laboratories, located in a basement level of a university facility equipped with a humidified air conditioning system, complained of cough and/or asthma and/or rhinitis during their normal working activities. since exposure to toxic compounds was very low (similar to that of the outdoor environment) only microbiological monitoring was performed. aspergillus fumigatus and penicillium notatum were found in some laboratories. eight laboratory workers (including the ... | 1999 | 12793962 |
effect of penicillium chrysogenum and debaryomyces hansenii on the volatile compounds during controlled ripening of pork loins. | during ripening of meat products such as dry-cured ham, the moulds and yeasts that proliferate on the surface may contribute to flavour development. however, their contribution to volatile components of dry-cured meat products is not known. one strain each of penicillium chrysogenum and debaryomyces hansenii, selected from dry-cured ham by their proteolytic activity, were tested to determine their effect on the volatile compounds during ripening. sterile pork loins were inoculated and ripened fo ... | 2003 | 12810295 |
contribution of hydrolytic enzymes produced by saprophytic fungi to the decrease in plant toxicity caused by water-soluble substances in olive mill dry residue. | we studied the influence of saprophytic fungi on the toxic effect that the water-soluble substances in dry residues from olive (ador) have on the growth of plants. all saprophytic fungi were able to decrease the phytotoxicity of ador, although the toxicity of this residue did not decrease in the same way. penicillium chrysogenum was able to reduce the toxicity of ador when this residue was applied at the highest dose of 15%. fusarium lateritum, f. graminearum and mucor racemosus were able to red ... | 2004 | 12811426 |
[effect of alcoholic extracts of wild plants on the inhibition of growth of aspergillus flavus, aspergillus niger, penicillium chrysogenum, penicillium expansum, fusarium moniliforme and fusarium poae moulds]. | fungicidal activity of wild plants larrea tridentata, karwinskia humboldtiana, ricinus communis, eucalyptus globulus, ambrosia ambrosioides, nicotiana glauca, ambrosia confertiflora, datura discolor, baccharis glutinosa, proboscidea parviflora, solanum rostratum, jatropha cinerea, salpianthus macrodonthus y sarcostemma cynanchoides was evaluated against the moulds species aspergillus flavus, aspergillus niger, penicillium chrysogenum, penicillium expansum, fusarium poae y fusarium moniliforme mo ... | 2002 | 12828509 |
characterization of the penicillium chrysogenum antifungal protein paf. | the filamentous fungus penicillium chrysogenum abundantly secretes the small, highly basic and cysteine-rich protein paf ( penicillium antifungal protein). in this study, the antifungal activity of paf is described. paf inhibited the growth of a variety of filamentous fungi, including opportunistic human pathogenic and phytopathogenic fungi, whereas bacterial and yeast cells were unaffected. paf reduced the conidial germination and hyphal extension rates in a dose-dependent manner and induced se ... | 2003 | 12856109 |
[fungi growth in buildings]. | the results of research into occurrence of fungi in buildings are hereby presented. indoor air pollution balanced between 10(2)-10(3) cfu/m3. examined building surfaces have been found significantly mouldy. total number of fungi ranged from 3.28 x 10(5) to 9.75 x 10(10) cfu/100 cm2. the results of the research show the active development of this group of microorganisms. in rooms, over 30 fungi species belonging to 11 genera have been detected. the most frequently occurring ones were fungi genera ... | 2003 | 12870304 |
isolation, structure elucidation and biological activity of 8-o-methylaverufin and 1,8-o-dimethylaverantin as new antifungal agents from penicillium chrysogenum. | in the screening of fungi for bioactive components, 8-o-methylaverufin (1b) and 1,8-o-dimethylaverantin (2b) were isolated from the culture broth of penicillium chrysogenum. the structure of these new antibiotics were determined by interpretation of the 1d and 2d nmr spectra and by comparison of the nmr data with those of the structurally related averufin (1a) and averantin (2a). both compounds have moderate antifungal activity. | 2003 | 12870811 |
does the detoxification of penicillin side-chain precursors depend on microsomal monooxygenase and glutathione s-transferase in penicillium chrysogenum? | the glutathione (gsh) s-conjugation of 1,2-epoxy-3-(4'-nitrophenoxy)propane was catalysed predominantly by microsomal glutathione s-transferase (mgst) in penicillium chrysogenum. the specific mgst activity unlike the cytosolic gst (cgst) activity increased substantially when the penicillin side-chain precursor phenoxyacetic acid (poa) was included in the culture medium. therefore, a microsomal monooxygenase (causing possible release of epoxide intermediates) and mgst-dependent detoxification pat ... | 2003 | 12872310 |
three-dimensional structure of penicillium chrysogenum virus: a double-stranded rna virus with a genuine t=1 capsid. | although double-stranded (ds) rna viruses are a rather diverse group, they share general architectural principles and numerous functional features. all dsrna viruses, from the mammalian reoviruses to the bacteriophage phi6, including fungal viruses, share a specialized capsid involved in transcription and replication of the dsrna genome, and release of the viral plus strand rna. this ubiquitous capsid consists of 120 protein subunits in a so-called t=2 organization. the stringent requirements of ... | 2003 | 12888349 |
adsorption of ni2+ on the surface of molecularly imprinted adsorbent from penicillium chysogenum mycelium. | the adsorption capacity for ni2+ on to the surface molecular imprinting adsorbent on penicillium chysogenum mycelium (the surface-imprinted adsorbent) was 40-45 mg g(-1) (using 200 mg ni2+ l(-1)), two times of the mycelium adsorbent. the surface-imprinted adsorbent had good stability at ph 2 to approximately 8. the optimal concentration of edta for desorption was 0.1 to 0.5 g l(-1). the surface imprinted adsorbent could be reused 15 times without losing its uptake. | 2003 | 12889829 |
curvularia haloperoxidase: antimicrobial activity and potential application as a surface disinfectant. | a presumed antimicrobial enzyme system, the curvularia haloperoxidase system, was examined with the aim of evaluating its potential as a sanitizing agent. in the presence of hydrogen peroxide, curvularia haloperoxidase facilitates the oxidation of halides, such as chloride, bromide, and iodide, to antimicrobial compounds. the curvularia haloperoxidase system caused several-log-unit reductions in counts of bacteria (pseudomonas spp., escherichia coli, serratia marcescens, aeromonas salmonicida, s ... | 2003 | 12902249 |
antimicrobial activity of terpenoids from trichodesma amplexicaule roth. | t. amplexicaule roth. has been investigated phytochemically for biologically active constituents from the benzene extract. this yielded a mixture of terpenoids: beta-sitosterol, alpha-amyrin, lupeol, hexacosanoic acid, ceryl alcohol and hexacosane. the sequential extracts, isolated terpenoids and reference antibiotics were screened for their possible bioactivities against selected pathogenic bacteria, escherichia coli, staphylococcus aureus and fungi, aspergillus flavus and penicillium chrysogen ... | 2003 | 12916085 |
volatile metabolites from indoor molds grown on media containing wood constituents. | since volatile mold metabolites are used for the detection of mold growth in buildings, it was interesting to determine whether different indoor mold species show different affinity for the major components of wood, a common building material. growth and volatile metabolites were studied when aspergillus versicolor, penicillium chrysogenum, and p. palitans were grown on laboratory substrates containing the major wood constituents cellulose, xylan and lignin. microbial volatile organic compounds ... | 2003 | 12943002 |
[physiologic characteristics of smooth and rough forms of penicillium chrysogenum]. | 1952 | 12992632 | |
nitrogen metabolism of penicillium chrysogenum q 176. | 1952 | 12998621 | |
the effect of the carbohydrate nutrition on penicillin production by penicillium chrysogenum q-176. | 1953 | 13008431 | |
studies on amino acids in the mycelium of penicillium chrysogenum q 176. | 1952 | 13011892 | |
the effect of aeration on the utilization of respiratory substrates by penicillium chrysogenum in submerged culture. | 1953 | 13044908 | |
[aerosol administration of crude filtrates of penicillium notatum in suppurative infections of the respiratory tree]. | 1953 | 13051245 | |
recombination without sexual reproduction in penicillium chrysogenum. | 1953 | 13072606 | |
the oxidation of glucose by penicillium chrysogenum. | 1953 | 13084554 | |
forms of phosphorus in the penicillin-producing mold penicillium chrysogenum q-176. | 1953 | 13084655 | |
haemoglobin in moulds: neurospora crassa and penicillium notatum. | 1953 | 13087244 | |
[mutant effects of certain radiations and chemical substances on penicillium notatum]. | 1953 | 13095502 | |
[composition, digestibility and protein value of the mycelium of penicillium notatum; a contribution on use of the by-products of penicillin production]. | 1953 | 13095967 | |
hydrophilic penicillins produced by penicillium chrysogenum. | 1953 | 13099263 | |
induced variation and strain selection of penicillium chrysogenum in relation to titer of natural penicillins. | 1953 | 13116058 | |
the oxidation of lard oil by penicillium chrysogenum. | 1953 | 13118086 | |
[chemical studies on penicillium chrysogenum]. | 1953 | 13123998 | |
[studies on quantitative determination of mycelium in cultures of penicillium chrysogenum q 176]. | 1953 | 13124012 | |
organic acid metabolism of penicillium chrysogenum. i. lactate and acetate. | 1954 | 13126095 | |
the lactic dehydrogenase of penicillium chrysogenum. | 1954 | 13129209 | |
[observations on submerged culture of penicillium chrysogenum. i. mycelial growth and autolysis]. | 1953 | 13134615 | |
[observations on penicillium chrysogenum in submerged culture. ii. cytologic and cytochemical studies]. | 1953 | 13134616 | |
[the role of carbohydrates in media used for the production of conidia of penicillium chrysogenum in submerged cultures]. | 1954 | 13171743 | |
the oxidation of tricarboxylic acid cycle compounds by penicillium chrysogenum. | 1954 | 13174492 | |
isolation of isomaltose [6-(alpha-d-glucopyranosyl)d-glucose] from the culture filtrate of penicillium chrysogenum q-176. | 1954 | 13181460 | |
para-sexual recombination in penicillium chrysogenum. | 1954 | 13192307 | |
[biological research on gelatinolytic, fibrinolytic and antidotal enzymes present in culture filtrates of certain microorganisms and in particular in penicillium notatum, actinomyces griseus, bacillus subtilis, pseudomonas aeruginosa, proteus, chromobacterium prodigiosum and staphylococcus pyogenes]. | 1954 | 13195286 | |
[method of staining nuclei in cells of penicillium chrysogenum thom]. | 1954 | 13209891 | |
some aspects of the amino acid metabolism of penicillium chrysogenum. | 1954 | 13211973 | |
the effect of certain enzyme inhibitors on respiration and on penicillin formation by penicillium chrysogenum. | 1954 | 13221762 | |
spontaneous and induced variation in selected stocks of the penicillium chrysogenum series. | 1954 | 13229218 | |
[considerations on selection and mutation in new strains of penicillium chrysogenum]. | 1954 | 13231902 | |
transglucosidation in penicillium chrysogenum q-176; isolation and identification of the oligosaccharides. | 1955 | 13239572 | |
the effect of temperature changes on the production of penicillin by penicillium chrysogenum w49-133. | 1955 | 13269092 | |
dehydrogenases of the tricarboxylic acid cycle in penicillium chrysogenum. | 1955 | 13269164 | |
[utilization of various carbon sources by penicillium chrysogenum]. | 1955 | 13279554 | |
heidenhain's hematoxylin in cytological studies of penicillium notatum. | 1956 | 13298827 | |
a study of the genetics of penicillin-producing capacity in penicillium chrysogenum. | 1956 | 13306888 | |
electron microscopical studies of ultrathin sections in penicillium chrysogenum. | 1956 | 13319260 | |
[penicillium chrysogenum; mutant strains and relative technics]. | 1955 | 13321519 | |
occurrence of free nucleotides in penicillium chrysogenum. | 1956 | 13328879 | |
[transglucidation reaction in penicillium chrysogenum]. | 1955 | 13329117 | |
[the structure of a trisaccharide synthesized by action of penicillium chrysogenum on saccharose]. | 1955 | 13329126 | |
[action of penicillium chrysogenum on sucrose]. | 1955 | 13336440 | |
[the transgalactosidases of penicillium chrysogenum]. | 1955 | 13336447 | |
[influence of pure triglycerides as carbon source on the development of penicillium chrysogenum and on the production of penicillin in agitated flasks]. | 1955 | 13336449 | |
evidence for the formation and utilization of lactobionic acid by penicillium chrysogenum. | 1956 | 13355474 | |
penicillin production by high-yielding strains of penicillium chrysogenum. | 1956 | 13363392 | |
the biosynthesis of penicillin. 4. the synthesis of benzylpenicillin by washed mycelium of penicillium chrysogenum. | 1956 | 13363852 | |
biochemistry of filamentous fungi. iv. the significance of the tricarboxylic acid cycle in the oxidation of acetate by penicillium chrysogenum. | 1956 | 13366943 | |
[nitrogen metabolism in penicillium chrysogenum. i. modification of nitrogen substances in culture of penicillium chrysogenum in the process of fermentation]. | 1956 | 13369170 | |
carbohydrate metabolism of penicillium chrysogenum. | 1956 | 13376517 | |
[growth factors for saccharomyces cerevisiae produced by penicillium chrysogenum q 176]. | 1955 | 13395817 | |
isolation of adenylosuccinic acid from penicillium chrysogenum. | 1957 | 13400124 | |
demonstration of the pentose cycle reactions in penicillium chrysogenum. | 1957 | 13428673 | |
[nitrogen metabolism in penicillium chrysogenum. ii. investigations on nitrogen fractions in mycelia and in culture medium of penicillium chrysogenum]. | 1957 | 13440594 | |
a study of lipides of penicillium chrysogenum. | 1957 | 13463007 | |
[structure of a trisaccharide synthesized by the action of penicillium chrysogenum on sucrose]. | 1957 | 13466171 | |
[carbohydrate metabolism in penicillium chrysogenum]. | 1957 | 13483124 | |
structure of a new pyridine nucleotide isolated from penicillium chrysogenum. | 1957 | 13483663 | |
biosynthesis of benzylpenicillin by mycelial suspensions of penicillium chrysogenum. | 1957 | 13512278 | |
the identification of two lipid components in liver which enable penicillium notatum extracts to hydrolyse lecithin. | 1958 | 13522628 | |
[relation of activity of peroxidase and catalase in penicillium chrysogenum q-176 cultures to penicillin concentration in the medium]. | 1958 | 13522763 | |
[selection of non-pigmented strain of penicillium chrysogenum inmi-243]. | 1958 | 13540946 | |
the effect of nutrients on formation of penicillin by washed mycelium of penicillium chrysogenum. | 1958 | 13546167 | |
[chemical study of nucleotides of penicillium chrysogenum]. | 1957 | 13546427 | |
[a new pyridine nucleotide from penicillium chrysogenum]. | 1957 | 13546428 | |
[fractionation & characterization of oligosaccharides synthesized by the action of penicillium chrysogenum on lactose]. | 1957 | 13546429 | |
some properties of the cytochrome oxidase of penicillium chrysogenum. | 1958 | 13549363 | |
[morphological variability and antibiotic properties of strains of penicillium chrysogenum thom. and penicillium notatum west. isolated from various areas of the ussr]. | 1958 | 13551945 | |
the effect of glycerol on the biosynthesis of benzylpenicillin by the washed cells of penicillium chrysogenum. | 1958 | 13586268 | |
sulfate utilization by penicillin-producing mutants of penicillium chrysogenum. | 1958 | 13587479 | |
studies on the hydrolysis of lecithin by a penicillium notatum phospholipase b preparation. | 1958 | 13607409 | |
myo-inositol in the biosynthesis of benzylpenicillin by the mycelial suspensions of penicillium chrysogenum. | 1959 | 13619673 | |
[effect of chemical structure of carbohydrates on development and growth of mycelia penicillium chrysogenum inmi-243]. | 1958 | 13632415 | |
inhibitory action of amino-acid esters on the production of extracellular amylase by penicillium chrysogenum. | 1959 | 13632770 | |
[studies on the antimycotic effect of a metabolite of penicillium notatum h 1929]. | 1959 | 13636291 | |
[conditions for the cultivation of penicillium chrysogenum on synthetic media]. | 1959 | 13643761 | |
carbohydrate constituents of the mycelium of penicillium chrysogenum grown in media with different sources of carbon. | 1959 | 13644189 | |
the role of phospholipides in the metabolism of amino acids by the mold penicillium chrysogenum. | 1959 | 13650636 | |
identification of a compound related to 6-aminopenicillanic acid, isolated from culture media of penicillium chrysogenum. | 1961 | 13686415 | |
[the structure of galactosyl-lactose, a trisaccharide produced from lactose by penicillium chrysogenum thom]. | 1960 | 13686417 | |
action of mycophenolic acid on unstable diploids of penicillium chrysogenum. | 1961 | 13686418 | |
isolation of a substance affecting somatic segregation in diploid strains of penicillium chrysogenum and its identification with mycophenolic acid. | 1961 | 13686419 | |
studies on the kinetics of fungicidal action. i. the effect of concentration and time on the viability of penicillium notatum spores in solutions of phenol. | 1961 | 13692661 |