Publications
| Title | Abstract | Year Filter | PMID(sorted ascending) Filter |
|---|
| complete genome sequence of probiotic lactobacillus reuteri zlr003 isolated from healthy weaned pig. | lactobacillus reuteri zlr003 was isolated from the caecum mucosa of healthy weaned pigs with displaying probiotic properties in our laboratory. here, we present the complete genome sequence of l. reuteri zlr003, which consists of a circular 2,234,097bp chromosome (g+c content of 38.66%). such information will provide insights into the molecular mechanism of its probiotic activity and facilitate its application in animal production. | 2016 | 27130498 |
| [non-antibiotic strategies to prevent the recurrence of uncomplicated urinary tract infections in women]. | the aim of all medical treatment is "primum nihil nocere" ("first, do no harm").restoring the integrity of intestinal microbiota and optimising the immune response in recurrent infections, especially in the urinary tract, are treatment alternatives which are closer to this target than the usual focus on antibiotic prevention of recurrence.in the future, antibiotics will continue to be recommended for the prevention of urinary tract infections on a case-by-case basis. however, the problems of an ... | 2016 | 27138235 |
| biofilms of vaginal lactobacillus reuteri crl 1324 and lactobacillus rhamnosus crl 1332: kinetics of formation and matrix characterization. | adhesion and biofilm formation are strain properties that reportedly contribute to the permanence of lactobacilli in the human vagina. the kinetics of biofilm formation and the chemical nature of the biofilm matrix formed by lactobacillus reuteri crl (centro de referencia para lactobacilos culture collection) 1324 and lactobacillus rhamnosus crl 1332, vaginal beneficial strains, were evaluated in this work. crystal violet-stained microplate assay and techniques of epifluorescence, electron and c ... | 2016 | 27146055 |
| control of zymoseptoria tritici cause of septoria tritici blotch of wheat using antifungal lactobacillus strains. | this study explored an effective biological control agent based on lactic acid bacteria culture or culture supernatant, which was effective against fungicide-resistant zymoseptoria tritici, which causes septoria tritici blotch (stb). | 2016 | 27155088 |
| lactobacillus reuteri dsm 17938 for the management of functional abdominal pain in childhood: a randomized, double-blind, placebo-controlled trial. | to determine whether administration of lactobacillus reuteri dsm 17938 is beneficial in functional abdominal pain (fap) of childhood. | 2016 | 27156182 |
| heat-killed and live lactobacillus reuteri gmnl-263 exhibit similar effects on improving metabolic functions in high-fat diet-induced obese rats. | our objective was to investigate and compare the effects of heat-killed (hk) and live lactobacillus reuteri gmnl-263 (lr263) on insulin resistance and its related complications in high-fat diet (hfd)-induced rats. male sprague-dawley rats were fed with a hfd with either hk or live lr263 for 12 weeks. the increases in the weight gain, serum glucose, insulin, and lipid profiles in the serum and liver observed in the hfd group were significantly reduced after hk or live lr263 administration. feedin ... | 2016 | 27163114 |
| lactobacillus reuteri treatment and dss colitis: new insight into the mechanism of protection. | 2016 | 27228414 | |
| molecular cloning of kman coding for mannanase from klebsiella oxytoca kub-cw2-3 and its hybrid mannanase characters. | gene encoding for β-mannanase (e.c 3.2.1.78) from klebsiella oxytoca kub-cw2-3 was cloned and expressed by an e. coli system resulting in 400 times higher mannanase activities than the wild type. a 3314bp dna fragment obtained revealed an open reading frame of 1164bp, namely kman-2, which encoded for 387 amino acids with an estimated molecular weight of 43.2kda. it belonged to the glycosyl hydrolase family 26 (gh26) exhibited low similarity of 50-71% to β-mannanase produced by other microbial so ... | 2016 | 27233126 |
| phenotypic and genotypic screening of human-originated lactobacilli for vitamin b12 production potential: process validation by micro-assay and uflc. | vitamin b12 (b12) production is a strain specific, rare and hidden functional attribute of lactobacilli and a cogent protocol for selection of such isolates from the herd of lactobacilli is required. the present study included isolation of lactobacilli from human samples (milk and fecal), screening them by a polyphasic (three-phase) methodology for probable b12 production potential and validating the screening protocol by exploring selected strains for in vitro vitamin production (two-phase ferm ... | 2016 | 27234139 |
| antifungal sourdough lactic acid bacteria as biopreservation tool in quinoa and rice bread. | the use of sourdough fermented with specific strains of antifungal lactic acid bacteria can reduce chemical preservatives in bakery products. the main objective of this study was to investigate the production of antifungal carboxylic acids after sourdough fermentation of quinoa and rice flour using the antifungal strains lactobacillus reuteri r29 and lactobacillus brevis r2δ as bioprotective cultures and the non-antifungal l. brevis l1105 as a negative control strain. the impact of the fermentat ... | 2016 | 27236463 |
| biofilm-forming capacity in biogenic amine-producing bacteria isolated from dairy products. | biofilms on the surface of food industry equipment are reservoirs of potentially food-contaminating bacteria-both spoilage and pathogenic. however, the capacity of biogenic amine (ba)-producers to form biofilms has remained largely unexamined. bas are low molecular weight, biologically active compounds that in food can reach concentrations high enough to be a toxicological hazard. fermented foods, especially some types of cheese, accumulate the highest ba concentrations of all. the present work ... | 2016 | 27242675 |
| effect of reuterin-producing lactobacillus reuteri coupled with glycerol on the volatile fraction, odour and aroma of semi-hard ewe milk cheese. | the effect of the biopreservation system formed by lactobacillus reuteri inia p572, a reuterin-producing strain, and glycerol (required for reuterin production), on the volatile fraction, aroma and odour of industrial sized semi-hard ewe milk cheese (castellano type) was investigated over a 3-month ripening period. the volatile compounds were extracted and analyzed by spme-gc-ms and cheese odour and aroma profiles were studied by descriptive sensory analysis. control cheese was made only with a ... | 2016 | 27289193 |
| structure-function relationships of bacterial and enzymatically produced reuterans and dextran in sourdough bread baking application. | exopolysaccharides from lactic acid bacteria may improve texture and shelf life of bread. the effect of exopolysaccharides on bread quality, however, depends on properties of the eps and the eps producing strain. this study investigated structure-function relationships of eps in baking application. the dextransucrase dsrm and the reuteransucrase gtfa were cloned from weissella cibaria 10m and lactobacillus reuteri tmw1.656, respectively, and heterologously expressed in escherichia coli. site-dir ... | 2016 | 27321351 |
| doses lactobacillus reuteri depend on adhesive ability to modulate the intestinal immune response and metabolism in mice challenged with lipopolysaccharide. | the objective of this study was to evaluate the modulatory effects of lactobacillus reuteri zj617 and zj615, which have high and low adhesive abilities, respectively, and lactobacillus rhamnosus gg (lgg) on immune responses and metabolism in mice stimulated with lipopolysaccharide (lps). six c57bl/6 mice per group were orally inoculated with zj617, zj615 or lgg for one week (1 × 10(8) cfu/mouse) and i.p. injected with lps (10 mg/kg) for 24 h. compared with the lps stimulation group, zj615, zj617 ... | 2016 | 27323686 |
| antiviral activity of lactobacillus reuteri protectis against coxsackievirus a and enterovirus 71 infection in human skeletal muscle and colon cell lines. | recurrence of hand, foot and mouth disease (hfmd) pandemics continues to threaten public health. despite increasing awareness and efforts, effective vaccine and drug treatment have yet to be available. probiotics have gained recognition in the field of healthcare worldwide, and have been extensively prescribed to babies and young children to relieve gastrointestinal (gi) disturbances and diseases, associated or not with microbial infections. since the faecal-oral axis represents the major route ... | 2016 | 27341804 |
| folc2-mediated folate metabolism contributes to suppression of inflammation by probiotic lactobacillus reuteri. | bacterial-derived compounds from the intestinal microbiome modulate host mucosal immunity. identification and mechanistic studies of these compounds provide insights into host-microbial mutualism. specific lactobacillus reuteri strains suppress production of the proinflammatory cytokine, tumor necrosis factor (tnf), and are protective in a mouse model of colitis. human-derived l. reuteri strain atcc pta 6475 suppresses intestinal inflammation and produces 5,10-methenyltetrahydrofolic acid polygl ... | 2016 | 27353144 |
| beneficial effect of synbiotic supplementation on hepatic steatosis and anthropometric parameters, but not on gut permeability in a population with nonalcoholic steatohepatitis. | nonalcoholic fatty liver disease is the most prevalent chronic liver disease in western countries; it can progress to nonalcoholic steatohepatitis (nash), cirrhosis and hepatocarcinoma. the importance of gut-liver-adipose tissue axis has become evident and treatments targeting gut microbiota may improve inflammatory and metabolic parameters in nash patients. in a randomized, controlled clinical trial, involving 50 biopsy-proven nash patients, we investigated the effects of synbiotic supplementat ... | 2016 | 27367724 |
| probiotics for irritable bowel syndrome: clinical data in children. | the purpose of this review was to summarize the evidence regarding probiotics treatment for pediatric ibs. | 2016 | 27380595 |
| resonance raman spectroscopic study of the interaction between co(ii)rrinoids and the atp:corrinoid adenosyltransferase pduo from lactobacillus reuteri. | the human-type atp:corrinoid adenosyltransferase pduo from lactobacillus reuteri (lrpduo) catalyzes the adenosylation of co(ii)rrinoids to generate adenosylcobalamin (adocbl) or adenosylcobinamide (adocbi(+)). this process requires the formation of "supernucleophilic" co(i)rrinoid intermediates in the enzyme active site which are properly positioned to abstract the adeonsyl moiety from co-substrate atp. previous magnetic circular dichroism (mcd) spectroscopic and x-ray crystallographic analyses ... | 2016 | 27383231 |
| effect of supplementation of yeast with bacteriocin and lactobacillus culture on growth performance, cecal fermentation, microbiota composition, and blood characteristics in broiler chickens. | the aim of the present study was to investigate the effect of yeast with bacteriocin and lactobacillus cultures (mixture of lactobacillus agilis bcrc 10436 and lactobacillus reuteri bcrc 17476) supplements, alone or in combination, on broiler chicken performance. | 2017 | 27383813 |
| evaluation of acrylamide-removing properties of two lactobacillus strains under simulated gastrointestinal conditions using a dynamic system. | the aim of this study was to evaluate the capability of lactobacillus reuteri nrrl 14171 and lactobacillus casei shirota to remove dietary acrylamide (aa) under simulated gastrointestinal conditions using a dynamic system. the effects of different aa levels or bacteria concentration on toxin removal by lactobacillus strains were assessed. thereafter, aa-removing capability of bacteria strains under either fasting or postprandial simulated gastrointestinal conditions was evaluated. commercial pot ... | 2016 | 27393995 |
| benzoic acid production with respect to starter culture and incubation temperature during yogurt fermentation using response surface methodology. | benzoic acid is occasionally used as a raw material supplement in food products and is sometimes generated during the fermentation process. in this study, the production of naturally occurring yogurt preservatives was investigated for various starter cultures and incubation temperatures, and considered food regulations. streptococcus thermophilus, lactobacillus acidophilus, lactobacillus delbrueckii subsp. bulgaricus, lactobacillus rhamnosus, lactobacillus casei, lactobacillus paracasei, lactoba ... | 2016 | 27433115 |
| elucidating and regulating the acetoin production role of microbial functional groups in multispecies acetic acid fermentation. | acetoin (3-hydroxy-2-butanone) formation in vinegar microbiota is crucial for the flavor quality of zhenjiang aromatic vinegar, a traditional vinegar produced from cereals. however, the specific microorganisms responsible for acetoin formation in this centuries-long repeated batch fermentation have not yet been clearly identified. here, the microbial distribution discrepancy in the diacetyl/acetoin metabolic pathway of vinegar microbiota was revealed at the species level by a combination of meta ... | 2016 | 27451452 |
| regular consumption of lactobacillus reuteri-containing lozenges reduces pregnancy gingivitis: an rct. | this randomized controlled trial assessed the impact of lactobacillus reuteri on pregnancy gingivitis in healthy women. | 2016 | 27461133 |
| probiotic lactobacilli modulate staphylococcus aureus-induced activation of conventional and unconventional t cells and nk cells. | lactobacilli are probiotic commensal bacteria and potent modulators of immunity. when present in the gut or supplemented as probiotics, they beneficially modulate ex vivo immune responsiveness. further, factors derived from several lactobacilli strains act immune regulatory in vitro. in contrast, staphylococcus aureus (s. aureus) is known to induce excessive t cell activation. in this study, we aimed to investigate s. aureus-induced activation of human mucosal-associated invariant t cells (mait ... | 2016 | 27462316 |
| structural basis for the roles of starch and sucrose in homo-exopolysaccharide formation by lactobacillus reuteri 35-5. | lactic acid bacteria (lab) produce exopolysaccharides (eps) that are important for biofilm formation in the mammalian oral cavity and gastrointestinal tract. sucrose is a well-known substrate for homo-eps formation by lactobacillus reuteri glucansucrases (gs). starch is the main fermentable carbohydrate in the human diet, and often consumed simultaneously with sucrose. recently we have characterized l. reuteri strains that also possess 4,6-α-glucanotransferases (4,6-α-gtases) that act on starch ... | 2016 | 27474540 |
| heat-killed lactobacillus reuteri gmnl-263 prevents epididymal fat accumulation and cardiac injury in high-calorie diet-fed rats. | high-calorie diet-induced obesity leads to cardiomyocyte dysfunction and apoptosis. impaired regulation of epididymal fat content in obese patients has been known to increase the risk of cardiac injury. in our study, a lactic acid bacteria, lactobacillus reuteri gmnl-263, was evaluated for its potential to reduce body weight and body fat ratio and to prevent heart injury in rats with high-fat diet-induced obesity. lactic acid bacteria supplementation restored the cardiac function and decreased t ... | 2016 | 27499689 |
| site directed mutagenesis of dextransucrase dsrm from weissella cibaria: transformation to a reuteransucrase. | glucansucrases produce α-glucans and gluco-oligosaccharides; the linkage type and molecular weight of glucans impacts their functionality. this study compared the catalytic specificities of dextransucrase dsrm from weissella cibaria 10m and derivatives of this enzymes with gtfa from lactobacillus reuteri tmw1.656. the n-variable region, which is dispensable for gtfa activity, was essential for dsrm activity. parallel amino acid substitutions in dsrm-δs and gtfa-δn indicated that the acceptor bin ... | 2016 | 27550198 |
| draft genome sequence of lactobacillus reuteri strain crl 1098, an interesting candidate for functional food development. | we report here the draft genome sequence of lactobacillus reuteri strain crl 1098. this strain represents an interesting candidate for functional food development because of its proven probiotic properties. the draft genome sequence is composed of 1,969,471 bp assembled into 45 contigs and an average g+c content of 38.8%. | 2016 | 27563038 |
| effect of lactobacillus casei- casei and lactobacillus reuteri on acrylamide formation in flat bread and bread roll. | the aim of this study was the evaluation of fermentation by lactic acid bacteria (lab) contains lactobacillus (l.) casei- casei and l. reuteri on acrylamide formation and physicochemical properties of the iranian flat bread named, sangak, and bread roll. sangak and bread roll were made with whole and white wheat flour, respectively. whole-wheat flour had upper content of protein, sugar, ash, fiber, damaged starch and the activity of amylase than the white wheat flour. after 24 h of fermentation, ... | 2016 | 27570278 |
| oral lactobacillus rhamnosus gr-1 and lactobacillus reuteri rc-14 to reduce group b streptococcus colonization in pregnant women: a randomized controlled trial. | this study is to examine the effect of lactobacillus rhamnosus gr-1 and lactobacillus reuteri rc-14 taken orally before bedtime on group b streptococcus (gbs)-positive pregnant women with respect to becoming gbs negative. | 2016 | 27590374 |
| the role of probiotics in prevention of oral diseases. | the dynamic development of knowledge in the field of probiotics was commenced at the beginning of the 20th century. since then, many ways of their possible usage in medicine have been established. in accordance with the who, probiotics are live microorganisms, which if applied in adequate amounts may benefit the host. among probiotics, fungi and bacteria are distinguished, and mechanisms of action of these organisms in the oral cavity and gut are parallel. application in dentistry, in prophylaxi ... | 2016 | 27594560 |
| horizontal transfer of the salmonella enterica serovar infantis resistance and virulence plasmid pesi to the gut microbiota of warm-blooded hosts. | salmonella enterica serovar infantis is one of the prevalent salmonellae worldwide. recently, we showed that the emergence of s infantis in israel was facilitated by the acquisition of a unique megaplasmid (pesi) conferring multidrug resistance and increased virulence phenotypes. here we elucidate the ecology, transmission properties, and regulation of pesi. we show that despite its large size (~280 kb), pesi does not impose a significant metabolic burden in vitro and that it has been recently f ... | 2016 | 27601577 |
| probiotic administration among free-living older adults: a double blinded, randomized, placebo-controlled clinical trial. | diseases of the digestive system have been found to contribute to a higher symptom burden in older adults. thus, therapeutic strategies able to treat gastrointestinal discomfort might impact the overall health status and help older adults to increase their overall health status and optimal functionality. | 2016 | 27612653 |
| lactobacillus reuteri and staphylococcus aureus differentially influence the generation of monocyte-derived dendritic cells and subsequent autologous t cell responses. | in early-life, the immature mucosal barrier allows contact between the gut microbiota and the developing immune system. due to their strategic location and their ability to sample luminal antigen, dendritic cells (dc) play a central role in the interaction of microbes and immune cells in the gut. here, we investigated how two bacteria associated with opposite immune profiles in children, that is, lactobacillus (l.) reuteri and staphylococcus (s.) aureus, influenced the differentiation of monocyt ... | 2016 | 27621814 |
| synthesis of taste-active γ-glutamyl dipeptides during sourdough fermentation by lactobacillus reuteri. | this study aimed to assess whether peptides influence the taste of sourdough bread. γ-glutamyl dipeptides with known kokumi taste threshold, namely γ-glu-glu, γ-glu-leu, γ-glu-ile, γ-glu-phe, γ-glu-met, and γ-glu-val, were identified in sourdough by liquid chromatography-tandem mass spectrometry in mrm mode. γ-glutamyl dipeptides were found in higher concentrations in sourdough fermented with lactobacillus reuteri when compared to the chemically acidified controls. proteolysis was an important f ... | 2016 | 27641253 |
| lactobacillus reuteri dsm 17938 plus vitamin d3 as ancillary treatment in allergic children with asthma. | 2016 | 27720582 | |
| structural determinants of alternating (α1 → 4) and (α1 → 6) linkage specificity in reuteransucrase of lactobacillus reuteri. | the glucansucrase gtfa of lactobacillus reuteri 121 produces an α-glucan (reuteran) with a large amount of alternating (α1 → 4) and (α1 → 6) linkages. the mechanism of alternating linkage formation by this reuteransucrase has remained unclear. gtfo of the probiotic bacterium lactobacillus reuteri atcc 55730 shows a high sequence similarity (80%) with gtfa of l. reuteri 121; it also synthesizes an α-glucan with (α1 → 4) and (α1 → 6) linkages, but with a clearly different ratio compared to gtfa. i ... | 2016 | 27748434 |
| techno-functional differentiation of two vitamin b12 producing lactobacillus plantarum strains: an elucidation for diverse future use. | an appropriate selection of lactobacillus strain (probiotic/starter/functional) on the basis of its techno-functional characteristics is required before developing a novel fermented functional food. we compared vitamin b12 (b12, cobalamin) producing lactobacillus plantarum isolates, bhm10 and bcf20, for functional (vitamin over-production, genomic insight to b12 structural genes, and probiotic attributes) and technological [milks (skim and soy) fermentation and b12 bio-fortification] characteris ... | 2017 | 27752783 |
| changes in the diversity and composition of gut microbiota of weaned piglets after oral administration of lactobacillus or an antibiotic. | the gut microbiota plays important roles in the health and well-being of animals, and high-throughput sequencing facilitates exploration of microbial populations in the animal gut. however, previous studies have focused on fecal samples instead of the gastrointestinal tract. in this study, we compared the microbiota diversity and composition of intestinal contents of weaned piglets treated with lactobacillus reuteri or chlortetracycline (aureomycin) using high-throughput sequencing. nine weaned ... | 2016 | 27757509 |
| microbes and oxytocin: benefits for host physiology and behavior. | it is now understood that gut bacteria exert effects beyond the local boundaries of the gastrointestinal tract to include distant tissues and overall health. prototype probiotic bacterium lactobacillus reuteri has been found to upregulate hormone oxytocin and systemic immune responses to achieve a wide array of health benefits involving wound healing, mental health, metabolism, and myoskeletal maintenance. together these display that the gut microbiome and host animal interact via immune-endocri ... | 2016 | 27793228 |
| dietary gluten-induced gut dysbiosis is accompanied by selective upregulation of micrornas with intestinal tight junction and bacteria-binding motifs in rhesus macaque model of celiac disease. | the composition of the gut microbiome reflects the overall health status of the host. in this study, stool samples representing the gut microbiomes from 6 gluten-sensitive (gs) captive juvenile rhesus macaques were compared with those from 6 healthy, age- and diet-matched peers. a total of 48 samples representing both groups were studied using v4 16s rrna gene dna analysis. samples from gs macaques were further characterized based on type of diet administered: conventional monkey chow, i.e., whe ... | 2016 | 27801835 |
| draft genome sequences of lactobacillus animalis strain p38 and lactobacillus reuteri strain p43 isolated from chicken cecum. | here, we present the genome sequence of lactobacillus animalis strain p38 and lactobacillus reuteri strain p43, both isolated from the cecum content of a 4-week old chicken fed a diet supplemented with the prebiotic β(1-4)galacto-oligosaccharide (gos). these indigenous lactobacillus isolates are potential probiotic organisms for poultry. | 2016 | 27811108 |
| microbial lysate upregulates host oxytocin. | neuropeptide hormone oxytocin has roles in social bonding, energy metabolism, and wound healing contributing to good physical, mental and social health. it was previously shown that feeding of a human commensal microbe lactobacillus reuteri (l. reuteri) is sufficient to up-regulate endogenous oxytocin levels and improve wound healing capacity in mice. here we show that oral l. reuteri-induced skin wound repair benefits extend to human subjects. further, dietary supplementation with a sterile lys ... | 2017 | 27825953 |
| orally administered multispecies probiotic formulations to prevent uro-genital infections: a randomized placebo-controlled pilot study. | the aim of this study was to evaluate in the vagina of 60 pre-menopausal women the detection of orally administered multispecies probiotic formulations showing anti-microbial properties in test in vitro. | 2017 | 27826653 |
| crosslinked, cryostructured lactobacillus reuteri monoliths for production of 3-hydroxypropionaldehyde, 3-hydroxypropionic acid and 1,3-propanediol from glycerol. | crosslinked, cryostructured monoliths prepared from lactobacillus reuteri cells were evaluated as potential immobilized whole-cell biocatalyst for conversion of glycerol, to potentially important chemicals for the biobased industry, i.e. 3-hydroxypropionaldehyde (3hpa), 3-hydroxypropionic acid (3hp) and 1,3-propanediol (1,3pdo). glutaraldehyde, oxidized dextran and activated polyethyleneimine/modified polyvinyl alcohol (pei/pva) were evaluated as crosslinkers; the latter gave highly stable prepa ... | 2017 | 27829124 |
| metabolic engineering for probiotics and their genome-wide expression profiling. | probiotic supplements in food industry have attracted a lot of attention and shown a remarkable growth in this field. metabolic engineering (me) approaches enable understanding their mechanism of action and increases possibility of designing probiotic strains with desired functions. probiotic microorganisms generally referred as industrially important lactic acid bacteria (lab) which are involved in fermenting dairy products, food, beverages and produces lactic acid as final product. a number of ... | 2016 | 27834122 |
| use of atomic force microscopy to study the multi-modular interaction of bacterial adhesins to mucins. | the mucus layer covering the gastrointestinal (gi) epithelium is critical in selecting and maintaining homeostatic interactions with our gut bacteria. however, the molecular details of these interactions are not well understood. here, we provide mechanistic insights into the adhesion properties of the canonical mucus-binding protein (mub), a large multi-repeat cell-surface adhesin found in lactobacillus inhabiting the gi tract. we used atomic force microscopy to unravel the mechanism driving mub ... | 2016 | 27834807 |
| a combination of lactic acid bacteria regulates escherichia coli infection and inflammation of the bovine endometrium. | uterine function in cattle is compromised by bacterial contamination and inflammation after calving. the objective of this study was to select a combination of lactic acid bacteria (lab) to decrease endometrium inflammation and escherichia coli infection. primary endometrial epithelial cells were cultured in vitro to select the most favorable lab combination modulating basal tissue inflammation and e. coli infection. supernatants were obtained to determine expression of pro-inflammatory cytokine ... | 2017 | 27837977 |
| erratum to: antiviral activity of lactobacillus reuteri protectis against coxsackievirus a and enterovirus 71 infection in human skeletal muscle and colon cell lines. | 2016 | 27855715 | |
| presence of lactobacillus reuteri in saliva coincide with higher salivary iga in young adults after intake of probiotic lozenges. | the aim of this study was to compare the concentration of salivary immunoglobulin a (iga) and the selected interleukins (il)-1β, il-6, il-8 and il-10 in young individuals with presence and non-presence of lactobacillus reuteri in saliva after a three-week intervention with probiotic lozenges. the study group consisted of 47 healthy individuals aged 18-32 years with no clinical signs of oral inflammation. in a randomised, double-blind, placebo-controlled, cross-over trial participants ingested tw ... | 2017 | 27873545 |
| asymmetric chemoenzymatic synthesis of 1,3-diols and 2,4-disubstituted aryloxetanes by using whole cell biocatalysts. | regio- and stereo-selective reduction of substituted 1,3-aryldiketones, investigated in the presence of different whole cell microorganisms, was found to afford β-hydroxyketones or 1,3-diols in very good yields (up to 95%) and enantiomeric excesses (up to 96%). the enantiomerically enriched aldols, obtained with the opposite stereo-preference by baker's yeast and lactobacillus reuteri dsm 20016 bioreduction, could then be diastereoselectively transformed into optically active syn- or anti-1,3-di ... | 2016 | 27878162 |
| effects of feeding fermented wheat with lactobacillus reuteri on gut morphology, intestinal fermentation, nutrient digestibility, and growth performance in weaned pigs. | feeding fermented feed to weaned pigs may improve nutrient digestibility and gut health and thereby reduce diarrhea incidence. effects of feeding wheat grain fermented for 24 h with were evaluated with 36 weaned pigs (7.3 kg bw). fermented wheat grain contained (dm basis) 14.2% cp, 0.45% chemically available lys, and 7.8% ndf, whereas unfermented wheat grain contained 16.4% cp, 0.45% chemically available lys, and 9.9% ndf. pigs were fed 6 mash wheat-based diets balanced for water content during ... | 2016 | 27898943 |
| a study on enhanced expression of 3-hydroxypropionic acid pathway genes and impact on its production in lactobacillus reuteri. | 3-hydroxypropionic acid (3-hp) is a novel antimicrobial agent against foodborne pathogens like salmonella and staphylococcus species. lactobacillus reuteri converts glycerol into 3-hp using a coenzyme a-dependent pathway, which is encoded by propanediol utilization operon (pdu) subjected to catabolite repression. in a catabolite-repression-deregulated l. reuteri rprb3007, quantitative pcr revealed a 2.5-fold increase in the transcripts of the genes pdup, pduw and pdul during the mid-log phase of ... | 2015 | 27904365 |
| lactobacillus reuteri dsm 17938 in the treatment of functional abdominal pain in children - rct study. | beneficial therapeutic effect of probiotics has been reported in children with the irritable bowel syndrome (ibs) but not consistently in other functional abdominal pain-related disorders. the aim of this study was to investigate the effect of lactobacillus (l.) reuteri dsm 17938 in the treatment of functional abdominal pain (fap) and ibs in children. | 2016 | 27906800 |
| expression of an (engineered) 4,6-α-glucanotransferase in potato results in changes in starch characteristics. | starch structure strongly influences starch physicochemical properties, determining the end uses of starch in various applications. to produce starches with novel structure and exploit the mechanism of starch granule formation, an (engineered) 4, 6-α-glucanotransferase (gtfb) from lactobacillus reuteri 121 was introduced into two potato genetic backgrounds: amylose-containing line kardal and amylose-free mutant amf. the resulting starches showed severe changes in granule morphology regardless of ... | 2016 | 27911907 |
| potential of lactobacillus reuteri from spontaneous sourdough as a starter additive for improving quality parameters of bread. | retardation of microbial spoilage of bread can be achieved by the use of spontaneous sourdough with an antimicrobial activity. this study was undertaken to identify lactic acid bacteria naturally occurring in spontaneous sourdough and use them for quality improvement and prolonging shelf life of rye, wheat and rye with wheat bread. identification of isolates from spontaneous sourdough by pyrosequencing assay showed that lactobacillus reuteri were dominant lactic acid bacteria. the isolates showe ... | 2016 | 27956866 |
| resetting microbiota by lactobacillus reuteri inhibits t reg deficiency-induced autoimmunity via adenosine a2a receptors. | regulatory t (t reg) cell deficiency causes lethal, cd4(+) t cell-driven autoimmune diseases. stem cell transplantation is used to treat these diseases, but this procedure is limited by the availability of a suitable donor. the intestinal microbiota drives host immune homeostasis by regulating the differentiation and expansion of t reg, th1, and th2 cells. it is currently unclear if t reg cell deficiency-mediated autoimmune disorders can be treated by targeting the enteric microbiota. here, we d ... | 2017 | 27994068 |
| effects of probiotic drop containing lactobacillus rhamnosus, bifidobacterium infantis, and lactobacillus reuteri on salivary streptococcus mutans and lactobacillus levels. | the aim of the present study was to evaluate the effect of a probiotic drop containing lactobacillus rhamnosus, bifidobacterium infantis, and lactobacillus reuteri on salivary counts of streptococcus mutans (sm) and lactobacillus (lb) in children 3-6 years of age. | 2017 | 27994413 |
| probiotic microorganisms inhibit epithelial cell internalization of botulinum neurotoxin serotype a. | botulinum neurotoxins (bonts) are some of the most poisonous natural toxins known to man and are threats to public health and safety. previous work from our laboratory showed that both bont serotype a complex and holotoxin can bind and transit through the intestinal epithelia to disseminate in the blood. the timing of bont/a toxin internalization was shown to be comparable in both the caco-2 in vitro cell culture and in the oral mouse intoxication models. probiotic microorganisms have been exten ... | 2016 | 27999281 |
| comparative study on the characteristics of weissella cibaria cmu and probiotic strains for oral care. | probiotics have been demonstrated as a new paradigm to substitute antibiotic treatment for dental caries, gingivitis, and chronic periodontitis. the present work was conducted to compare the characteristics of oral care probiotics: weissella cibaria cmu (chonnam medical university) and four commercial probiotic strains. survival rates under poor oral conditions, acid production, hydrogen peroxide production, as well as inhibition of biofilm formation, coaggregation, antibacterial activity, and i ... | 2016 | 27999400 |
| metabolic effects of lactobacillus reuteri dsm 17938 in people with type 2 diabetes: a randomized controlled trial. | to investigate the metabolic effects of 12-week oral supplementation with lactobacillus reuteri dsm 17938 in patients with type 2 diabetes on insulin therapy. | 2017 | 28009106 |
| effect of lactobacillus reuteri on cell viability and pge2 production in human gingival fibroblasts. | emerging evidence suggests that probiotic therapy can play a role in the prevention and management of oral inflammatory diseases through immunomodulation and down-regulation of the inflammatory cascade. the aim of this in vitro study was to investigate the viability of human gingival fibroblasts (hgf) and its production of prostaglandin e2 (pge2), when exposed to supernatants of two mixed lactobacillus reuteri strains (atcc pta 5289 and dsm 17938). the experiments were conducted in the presence ... | 2016 | 28028690 |
| redox balance in lactobacillus reuteri dsm20016: roles of iron-dependent alcohol dehydrogenases in glucose/ glycerol metabolism. | lactobacillus reuteri, a heterofermentative bacterium, metabolizes glycerol via a pdu (propanediol-utilization) pathway involving dehydration to 3-hydroxypropionaldehyde (3-hpa) followed by reduction to 1,3-propandiol (1,3-pdo) with concomitant generation of an oxidized cofactor, nad+ that is utilized to maintain cofactor balance required for glucose metabolism and even for oxidation of 3-hpa by a pdu oxidative branch to 3-hydroxypropionic acid (3-hp). the pdu pathway is operative inside pdu mic ... | 2016 | 28030590 |
| ultrasound attenuation of lactobacilli and bifidobacteria: effect on some technological and probiotic properties. | attenuation can be regarded as a tool to modulate the metabolism of probiotic bacteria and, consequently, a strategy to reduce the acidification of the active drinks. attenuation can be done through chemical and physical approaches and ultrasound (us) is a possibility, previously tested to modulate the metabolism of lactic acid bacteria inoculated in a rice drink, but no data are available on the effect of this treatment of the overall profile of probiotic bacteria. therefore, the main topic of ... | 2017 | 28038333 |
| characterisations of lactobacillus reuteri sk24.003 glucansucrase: implications for α-gluco-poly- and oligosaccharides biosynthesis. | glucansucrase was obtained from lactobacillus reuteri sk24.003 and its characterizations and in vitro biosynthesis for glucose polymer and oligosaccharides were investigated. the final specific activity of glucansucrase was 1.3iu/mg protein with 8.6-fold purification and 8.7% recovery. the molecular weight of purified enzyme was 166.0kda. the glucansucrase exhibited optimum activity at 30-35°c, whereas the maximum activity was obtained at ph 5.0-5.5. the double-charged ions including mg(2+), mn( ... | 2017 | 28041553 |
| the level of beta defensin-2 in saliva and its expression in parotid gland epithelial cells after probiotic (lactobacillus reuteri) induction to inhibit streptococcus mutans in caries. | the aim of this study was to prove that administrating l. reuteri probiotics can increase the level of bd-2 saliva and bd-2 expression in the epithelial parotid glands of wistar rats. | 2017 | 28042275 |
| effect of biochanin a on corn grain (zea mays) fermentation by bovine rumen amylolytic bacteria. | the objective was to determine the effect of biochanin a (bca), an isoflavone produced by red clover (trifolium pratense l.), on corn fermentation by rumen micro-organisms. | 2017 | 28055130 |
| lactobacillus reuteri dsm 17938 in the prevention of antibiotic-associated diarrhoea in children: protocol of a randomised controlled trial. | administration of some probiotics appears to reduce the risk of antibiotic-associated diarrhoea (aad). the effects of probiotics are strain-specific, thus, the efficacy and safety of each probiotic strain should be established separately. we aim to assess the effects of lactobacillus reuteri dsm 17938 administration for the prevention of diarrhoea and aad in children. | 2017 | 28057659 |
| 4,3-α-glucanotransferase, a novel reaction specificity in glycoside hydrolase family 70 and clan gh-h. | lactic acid bacteria possess a diversity of glucansucrase (gs) enzymes that belong to glycoside hydrolase family 70 (gh70) and convert sucrose into α-glucan polysaccharides with (α1 → 2)-, (α1 → 3)-, (α1 → 4)- and/or (α1 → 6)-glycosidic bonds. in recent years 3 novel subfamilies of gh70 enzymes, inactive on sucrose but using maltodextrins/starch as substrates, have been established (e.g. gtfb of lactobacillus reuteri 121). compared to the broad linkage specificity found in gss, all gh70 starch-a ... | 2017 | 28059108 |
| global analysis of mannitol 2-dehydrogenase in lactobacillus reuteri crl 1101 during mannitol production through enzymatic, genetic and proteomic approaches. | several plants, fungi, algae, and certain bacteria produce mannitol, a polyol derived from fructose. mannitol has multiple industrial applications in the food, pharmaceutical, and medical industries, being mainly used as a non-metabolizable sweetener in foods. many heterofermentative lactic acid bacteria synthesize mannitol when an alternative electron acceptor such as fructose is present in the medium. in previous work, we reported the ability of lactobacillus reuteri crl 1101 to efficiently pr ... | 2017 | 28060932 |
| crystal structure of 4,6-α-glucanotransferase supports diet-driven evolution of gh70 enzymes from α-amylases in oral bacteria. | food processing and refining has dramatically changed the human diet, but little is known about whether this affected the evolution of enzymes in human microbiota. we present evidence that glycoside hydrolase family 70 (gh70) glucansucrases from lactobacilli, synthesizing α-glucan-type extracellular polysaccharides from sucrose, likely evolved from gh13 starch-acting α-amylases, via gh70 4,6-α-glucanotransferases. the crystal structure of a 4,6-α-glucanotransferase explains the mode of action an ... | 2017 | 28065507 |
| novel reuterin-related compounds suppress odour by periodontopathic bacteria. | halitosis is caused by volatile sulphur compounds including methyl mercaptan (ch3 sh) in the oral cavity and is a serious problem that limits interpersonal social communication. the aim of study was to evaluate the effects of reuterin-related compounds (rrcs) on halitosis-related periodontopathic bacteria in vitro. | 2017 | 28083982 |
| efficacy and safety of apt198k for the treatment of infantile colic: a pilot study. | comparing efficacy and safety of apt198k (xyloglucan plus heat-killed lactobacillus reuteri sgl01 and bifidobacterium brevis sgb01) versus a lactase dietary supplement as first-line treatment of infantile colic. | 2017 | 28114795 |
| luminometric label array for counting and differentiation of bacteria. | methods for simple and fast detection and differentiation of bacterial species are required, for instance, in medicine, water quality monitoring, and the food industry. here, we have developed a novel label array method for the counting and differentiation of bacterial species. this method is based on the nonspecific interactions of multiple unstable lanthanide chelates and selected chemicals within the sample leading to a luminescence signal profile that is unique to the bacterial species. it i ... | 2017 | 28194955 |
| erratum to: effect of lactobacillus reuteri on cell viability and pge2 production in human gingival fibroblasts. | 2017 | 28210874 | |
| use of phytone peptone to optimize growth and cell density of lactobacillus reuteri. | the objective of this study was to determine the use of phytone peptone to optimize the growth and cell density of lactobacillus reuteri. four strains of l. reuteri (dsm 20016, sd 2112, cf 2-7f, and mf 2-3,) were used in this study. an overnight culture of individual strains was inoculated into fresh basal media with various protein sources (peptone, tryptone, proteose peptone #3, phytone peptone, tryptic soy broth, yeast extract, and beef extract). samples were then mixed well and incubated at ... | 2015 | 28231207 |
| structural analysis of rebaudioside a derivatives obtained by lactobacillus reuteri 180 glucansucrase-catalyzed trans-α-glucosylation. | the wild-type gtf180-δn glucansucrase enzyme from lactobacillus reuteri 180 was found to catalyze the α-glucosylation of the steviol glycoside rebaudioside a, using sucrose as glucosyl donor in a transglucosylation process. structural analysis of the formed products by maldi-tof mass spectrometry, methylation analysis and nmr spectroscopy showed that rebaudioside a is specifically α-d-glucosylated at the steviol c-19 β-d-glucosyl moiety (55% conversion). the main product is a mono-(α1 → 6)-gluco ... | 2017 | 28231561 |
| catechol glucosides act as donor/acceptor substrates of glucansucrase enzymes of lactobacillus reuteri. | previously, we have shown that the glucansucrase gtfa-δn enzyme of lactobacillus reuteri 121, incubated with sucrose, efficiently glucosylated catechol and we structurally characterized catechol glucosides with up to five glucosyl units attached (te poele et al. in bioconjug chem 27:937-946, 2016). in the present study, we observed that upon prolonged incubation of gtfa-δn with 50 mm catechol and 1000 mm sucrose, all catechol had become completely glucosylated and then started to reappear. follo ... | 2017 | 28258313 |
| coproduction of colicin v and lactic acid bacteria bacteriocins in lactococci and enterococci strains of biotechnological interest. | the aim of this study was the coproduction in a single strain of the gram-negative bacteriocin colicin v with other bacteriocins from lactic acid bacteria (lab). | 2017 | 28261897 |
| possible correlation between levansucrase production and probiotic activity of bacillus sp. isolated from honey and honey bee. | five bacterial isolates from honey and bee gut were selected based on their high levansucrase activity and levan yield which were strongly positively correlated. all isolates showed good tolerance to temperature up to 70 °c, to nacl up to 3 m and to 0.1% h2o2. they maintained over 59 and 64% survival at ph 9.0 and 2.0 respectively, but showed varying tolerance to 0.1% bile salts and pancreatic enzymes. most isolates were susceptible to widely used antibiotics, but demonstrated diverse antimicrob ... | 2017 | 28271385 |
| draft genome sequence of lactobacillus reuteri 121, a source of α-glucan and β-fructan exopolysaccharides. | the probiotic bacterium lactobacillus reuteri 121 is a well-known producer of diverse homoexopolysaccharides (α-glucans and β-fructans) from sucrose and maltodextrins/starches of interest for food applications. here, we report the draft genome sequence of this strain, with a focus on carbohydrate-active enzymes. | 2017 | 28280024 |
| in vitro effect of vaginal lactobacilli on the growth and adhesion abilities of uropathogenic escherichia coli. | escherichia coli is one of the main causes of uncomplicated urinary tract infections and responsible of vaginal infections. lactobacilli can inhibit this pathogen by the production of antimicrobial substances as organic acids, hydrogen peroxide and/or bacteriocins. the aim of this work was to study the effects of beneficial vaginal lactobacilli on e. coli through in vitro experiments. the inhibitory activity of three vaginal lactobacillus strains against e. coli was assessed using the agar plate ... | 2017 | 28280842 |
| microbiome and metabolome modifying effects of several cardiovascular disease interventions in apo-e(-/-) mice. | there is strong evidence indicating that gut microbiota have the potential to modify, or be modified by the drugs and nutritional interventions that we rely upon. this study aims to characterize the compositional and functional effects of several nutritional, neutraceutical, and pharmaceutical cardiovascular disease interventions on the gut microbiome, through metagenomic and metabolomic approaches. apolipoprotein-e-deficient mice were fed for 24 weeks either high-fat/cholesterol diet alone (con ... | 2017 | 28285599 |
| correction: identification and characterization of sulfated carbohydrate-binding protein from lactobacillus reuteri. | [this corrects the article doi: 10.1371/journal.pone.0083703.]. | 2017 | 28291819 |
| hypocholesterolemic effects of probiotic mixture on diet-induced hypercholesterolemic rats. | growing evidence has indicated that supplementation with probiotics improves lipid metabolism. we aimed to investigate the beneficial effects of a probiotics mixture (pm) of three strains belonging to the species bifidobacterium (b. longum, b. lactis, and b. breve) and two strains belonging to the species lactobacillus (l. reuteri and l. plantarum) on cholesterol-lowering efficacy in hypercholesterolemic rats. a hypercholesterolemic rat model was established by feeding a high-cholesterol diet fo ... | 2017 | 28300786 |
| immobilization of β-galactosidases from lactobacillus on chitin using a chitin-binding domain. | two β-galactosidases from lactobacillus, including a heterodimeric laclm type enzyme from lactobacillus reuteri l103 and a homodimeric lacz type β-galactosidase from lactobacillus bulgaricus dsm 20081, were studied for immobilization on chitin using a carbohydrate-binding domain (chitin-binding domain, chbd) from a chitinolytic enzyme. three recombinant enzymes, namely, laclm-chbd, chbd-laclm, and lacz-chbd, were constructed and successfully expressed in lactobacillus plantarum wcfs1. depending ... | 2017 | 28319379 |
| lactobacillus reuteri surface mucus adhesins upregulate inflammatory responses through interactions with innate c-type lectin receptors. | the vertebrate gut symbiont lactobacillus reuteri exhibits strain-specific adhesion and health-promoting properties. here, we investigated the role of the mucus adhesins, cmba and mub, upon interaction of l. reuteri atcc pta 6475 and atcc 53608 strains with human monocyte-derived dendritic cells (modcs). we showed that mucus adhesins increased the capacity of l. reuteri strains to interact with modcs and promoted phagocytosis. our data also indicated that mucus adhesins mediate anti- and pro-inf ... | 2017 | 28326063 |
| probiotic lactobacillus reuteri has antifungal effects on oral candida species in vitro. | background: an alternative approach for managing candida infections in the oral cavity by modulating the oral microbiota with probiotic bacteria has been proposed. objective: the aim was to investigate the antifungal potential of the probiotic bacterium lactobacillus reuteri (dsm 17938 and atcc pta 5289) against six oral candida species (c. albicans, c. glabrata, c. krusei, c. tropicalis, c. dubliniensis, and c. parapsilosis). design: the lactobacilli were tested for their ability to co-aggregat ... | 2017 | 28326154 |
| production of reuterin in a fermented milk product by lactobacillus reuteri: inhibition of pathogens, spoilage microorganisms, and lactic acid bacteria. | we assessed the antimicrobial activity of reuterin produced in vitro in glycerol aqueous solutions in situ by lactobacillus reuteri atcc 53608 as part of a fermented milk product against starter (lactobacillus delbrueckii ssp. bulgaricus and streptococcus thermophilus), spoilage (penicillium expansum), pathogenic (staphylococcus aureus, salmonella enterica ssp. enterica, and listeria monocytogenes), and pathogen surrogate (escherichia coli dh5α) microorganisms. we also assayed the influence of c ... | 2017 | 28342608 |
| stressor exposure has prolonged effects on colonic microbial community structure in citrobacter rodentium-challenged mice. | stressor exposure significantly affects the colonic mucosa-associated microbiota, and exacerbates citrobacter rodentium-induced inflammation, effects that can be attenuated with probiotic lactobacillus reuteri. this study assessed the structure of the colonic mucosa-associated microbiota in mice exposed to a social stressor (called social disruption), as well as non-stressed control mice, during challenge with the colonic pathogen c. rodentium. mice were exposed to the social stressor or home ca ... | 2017 | 28344333 |
| molecular and biopharmaceutical investigation of alginate-inulin synbiotic co-encapsulation of probiotic to target the colon. | colon targeting, as a site-specific delivery for oral formulation, remains a major challenge, especially for sensitive bioactive components such as therapeutic forms of phages, live attenuated virus, and prebiotics-probiotics association. synbiotics could be used to protect encapsulated probiotics during the gastrointestinal tract and control their release in the colon. to achieve these goals, effective prebiotics such as inulin could be combined with alginate-the most exploited polymer used for ... | 2017 | 28350268 |
| a flow-cytometric method to evaluate eosinophil-mediated uptake of probiotic lactobacillus reuteri. | eosinophils are resident leukocytes of gut mucosa. here we present a combined flow cytometric-antibiotic protection assay to identify mouse eosinophils capable of bacterial uptake, specifically, gram-positive lactobacillus reuteri, in studies performed ex vivo. the assay may be adapted for use in vivo. | 2017 | 28359737 |
| antagonistic activity of lactobacillus reuteri strains on the adhesion characteristics of selected pathogens. | adhesion ability of probiotics is the key factor that decides their colonization in the gastrointestinal tract and potential to inhibit pathogens. therefore, adhesion ability can be considered as a key determinant for probiotic efficacy. presents study documents the antagonistic activity of viable/untreated, lithium chloride (licl) treated or heat-killed forms of eight probiotic lactobacillus reuteri strains on the adhesion characteristics of selected pathogens. all strains investigated were abl ... | 2017 | 28377765 |
| experimental evaluation of host adaptation of lactobacillus reuteri to different vertebrate species. | the species lactobacillus reuteri has diversified into host-specific lineages implying a long term association with different vertebrates. strains from rodent lineages show specific adaptations to mice, but the processes underlying the evolution of l. reuteri in other hosts remain unknown. we administered three standardized inocula composed of strains from different host-confined lineages to mice, pigs, chickens and humans. the ecological performance of each strain in the gastrointestinal tract ... | 2017 | 28389535 |
| enhanced probiotic potential of lactobacillus reuteri when delivered as a biofilm on dextranomer microspheres that contain beneficial cargo. | as with all orally consumed probiotics, the gram-positive bacterium lactobacillus reuteri encounters numerous challenges as it transits through the gastrointestinal tract of the host, including low ph, effectors of the host immune system, as well as competition with commensal and pathogenic bacteria, all of which can greatly reduce the availability of live bacteria for therapeutic purposes. recently we showed that l. reuteri, when adhered in the form of a biofilm to a semi-permeable biocompatibl ... | 2017 | 28396655 |
| analysis of antimicrobial and immunomodulatory substances produced by heterofermentative lactobacillus reuteri. | antimicrobial and immunomodulatory potential of various lactobacillus reuteri strains is closely connected to their metabolite production profile under given cultivation conditions. we determined the in vitro production of antimicrobial substances such as organic acids, ethanol, and reuterin by four strains of l. reuteri (l. reuteri e, l. reuteri ko5, l. reuteri ccm 3625, and l. reuteri atcc 55730). all studied l. reuteri strains showed the ability to produce lactic acid, acetic acid, and ethano ... | 2017 | 28401403 |
| optimization of reuterin production in cheese by lactobacillus reuteri. | cheeses manufactured from pasteurized milk supplemented with glycerol and reuterin-producing lactobacillus reuteri inia p572 as adjunct to the commercial starter culture were analysed in order to optimize a biopreservation strategy. the highest reuterin concentration determined by a colorimetric assay was detected on day 1 in cheeses with 100-500 mm glycerol. the presence of reuterin was confirmed by a direct detection technique as hplc. cheeses made with l. reuteri and 200 or 500 mm glycerol sh ... | 2017 | 28416886 |
| effect of lactobacillus reuteri (dsm 17938) on methane production in patients affected by functional constipation: a retrospective study. | constipation is a common symptom affecting up to 30% of the western population and is strongly associated with the presence of intestinal methanogens, which may directly inhibit motor activity. two recent studies performed on adult and children affected by chronic constipation showed that the supplementation with l. reuteri significantly improved bowel movements. whether its action is related to a decreasing of methane (ch4) production has never been tested. we have therefore designed a study ai ... | 2017 | 28429333 |
| expression of the clonostachys rosea lactonohydrolase gene by lactobacillus reuteri to increase its zearalenone-removing ability. | mycotoxins are secondary metabolites produced by filamentous fungi that can contaminate agricultural crops in the field as well as during harvest, transportation, processing, or storage. zearalenone (zen), a non-steroidal estrogenic mycotoxin, produced by fusarium species, has been shown to be associated with reproductive disorders in farm animals and to a lesser extent in hyperoestrogenic syndromes in humans. thus, the decontamination of zen in foods and feeds is an important issue. | 2017 | 28438205 |