Publications

[experience with dilatation of tight esophageal stenoses using a balloon catheter].	the dilatation of oesophageal stenoses with balloon catheters was made in 38 patients with 44 stenoses of different origin. the most frequent stenosis was localized in oesophagogastric or oesophagocolic anastomosis after oesophagectomy, postcorrosive stenoses an those after reflux oesophagitis. the stenoses were mostly of filiform type, the diameter being 1-3 mm (79%) less frequently 4-7 mm (21%). it became possible to dilate 37 stenoses up to 10 to 20 mm, four stenoses to 22 mm. in only three c ...	2008	2632022
studies on medicinal resources from livestock. i. anti-allergic effects of pig bile. (1).	anti-allergic activities of animal biles and commercially available bile acids were evaluated in experimental allergic disease models. pig bile exhibited marked preventive effects on the models of delayed-type hypersensitivity (type iv allergy), picryl chloride-induced contact dermatitis (pc-cd) and sheep red blood cells (srbc)-induced footpad swelling in mice. fel ursi (dried bear gallbladder) also had an inhibitory effect on pc-cd, whereas ox bile, chicken bile and bile acids had no effect on ...	1989	2632089
studies on medicinal resources from livestock. i. anti-allergic effects of pig bile. (1).	anti-allergic activities of animal biles and commercially available bile acids were evaluated in experimental allergic disease models. pig bile exhibited marked preventive effects on the models of delayed-type hypersensitivity (type iv allergy), picryl chloride-induced contact dermatitis (pc-cd) and sheep red blood cells (srbc)-induced footpad swelling in mice. fel ursi (dried bear gallbladder) also had an inhibitory effect on pc-cd, whereas ox bile, chicken bile and bile acids had no effect on ...	1989	2632089
[psychological approach in nursing. delusion associated with alcoholism].		2007	2632860
myofibroblasts in cotton-induced granulation tissue and the bovine adrenal capsule: morphological aspects.	ultrastructural studies of one week old cotton-induced granulation tissue revealed the presence of polymorphonuclear neutrophils (pmn), macrophages and mast cells, whilst the granulation tissue from two week old cotton implants contained fibroblasts, myofibroblasts and abundant collagen fibres. similarly, the bovine adrenal capsule contained both fibroblasts and myofibroblasts. it is proposed that the bovine adrenal capsule and two week cotton-induced granulation tissue could be utilized as in-v ...	1989	2634624
short chain fatty acid-induced colitis in mice.	short-chain fatty acids (e.g. acetic, propionic and butyric acid) are metabolic products produced by colonic bacteria. since intra-rectal instillation of dilute acetic acid to rats and cats has been reported to produce a diffuse colitis similar to the human disease, in our study we have investigated the effect of intra-rectal butyric acid in mice. male bka mice (n = 6) received 01 ml of dilute butyric acid by intra-rectal instillation which was flushed out with saline after 10 sec. control anima ...	1989	2634625
non-germ cell testicular tumours in nigerians.	non-germ cell testicular tumours are reported to be more common in peoples of negroid and asian descent than in caucasians. this group of tumours comprised seven of sixteen testicular tumours seen in a ten-year period at the university of benin teaching hospital, benin city, nigeria. however, unlike experiences elsewhere in africa and the west indies where paratesticular tumours accounted for a majority of these tumours, malignant lymphomas constituted over 70% of non-germinal testicular tumours ...	2008	2635452
non-germ cell testicular tumours in nigerians.	non-germ cell testicular tumours are reported to be more common in peoples of negroid and asian descent than in caucasians. this group of tumours comprised seven of sixteen testicular tumours seen in a ten-year period at the university of benin teaching hospital, benin city, nigeria. however, unlike experiences elsewhere in africa and the west indies where paratesticular tumours accounted for a majority of these tumours, malignant lymphomas constituted over 70% of non-germinal testicular tumours ...	2008	2635452
[measurement of orthodontic appliance force using prototype sensors].	in introductory remarks the most important biomechanical principles, which are relevant for the research, and conditions which must be satisfied presented in intraoral measuring of orthodontic forces were pointed out. first the aim of the research was defined, and then the investigation of mechanical properties of acrylics as a material for orthodontic appliances were carried out. the type of strain gauges, bonds and measuring system configurations, as well as measuring amplifiers and recording ...	2008	2635572
carotid cave aneurysms.		2009	2635881
[necrosis of the bone marrow].	the authors analyzed the incidence of necrosis of the bone marrow in nonselected autopsy material. the studies included 419 cases of various disease types. necrosis of the bone marrow was found in 83 cases (19.8%). it was most frequently observed in patients with neoplastic disease of the hematopoietic and lymphatic systems (26.3%) and malignant neoplasms of different origin (21.9%). in 40% cases necrosis of the bone marrow were accompanied by neoplastic metastases into the hematopoietic tissue, ...	2009	2637982
redirection of prostaglandin endoperoxide metabolism at the platelet-vascular interface in man.	prostacyclin (pgi2) is an inhibitor of platelet function in vitro. we tested the hypothesis that pgi2 is formed in biologically active concentrations at the platelet-vascular interface in man and can be pharmacologically modulated to enhance its inhibitory properties. this became feasible when we developed a microquantitative technique that permits the measurement of eicosanoids in successive 40-microliters aliquots of whole blood emerging from a bleeding time wound. in 13 healthy volunteers the ...	1989	2643628
internalization and degradation of insulin by a human insulin receptor-v-ros hybrid in chinese hamster ovary cells.	chinese hamster ovary cell lines expressing either the wild-type human insulin receptor or a hybrid molecule in which the tyrosine kinase domain of the insulin receptor is replaced with that of the oncogene, v-ros were examined for their ability to internalize and degrade insulin. cells expressing the hybrid receptor were found to internalize and degrade insulin at approximately half the rate of cells expressing the native insulin receptor. moreover, insulin was incapable of inducing the interna ...	1989	2645866
new system helps prevent medi-cal claim delays.		2009	2649431
lead toxicity and iron deficiency in utah migrant children.	we determined the frequency of presumptive iron deficiency and lead toxicity in 198 utah migrant children, ages 9-72 months, during the summer of 1985. there were no confirmed cases of lead toxicity. thirteen per cent of those tested and 30 per cent of the children ages 9-23 months were iron deficient. hematocrit determinations accurately predicted iron deficiency in only 35 per cent of the children confirmed to have this disorder via erythrocyte protoporphyrin screening.	2009	2650572
lead toxicity and iron deficiency in utah migrant children.	we determined the frequency of presumptive iron deficiency and lead toxicity in 198 utah migrant children, ages 9-72 months, during the summer of 1985. there were no confirmed cases of lead toxicity. thirteen per cent of those tested and 30 per cent of the children ages 9-23 months were iron deficient. hematocrit determinations accurately predicted iron deficiency in only 35 per cent of the children confirmed to have this disorder via erythrocyte protoporphyrin screening.	2009	2650572
therapeutic implications of tumor heterogeneity.	at the outset of this review, we stated that we wished to raise some questions that challenge the commonly held view that tumor heterogeneity is of major significance to treatment failure. the nature of this challenge is the following: although tumor heterogeneity in sensitivity to therapeutic agents has been demonstrated repeatedly, using isolated subpopulations of cells, primarily in cell culture systems, there is very little work that has been directed toward asking the tough questions about ...	1989	2652316
no association between post-transplant erythrocytosis, thromboembolic events, and cyclosporine therapy.		2009	2652691
bone marrow transplantation for acute lymphoblastic leukaemia in first and second remission.		2009	2653514
weakness in patients with hemiparesis.	clinical and experimental results are reviewed concerning muscle weakness in patients with hemiparesis after a stroke. the discussion includes the important role that alterations in the physiology of motor units, notably changes in firing rates and muscle fiber atrophy, play in the manifestation of muscle weakness. this role is compared with the lesser role that spasticity (defined as hyperactive stretch reflexes) of the antagonist muscle group appears to play in determining the weakness of agon ...	2009	2655457
[relapsing polychondritis. an infrequent cartilage disease].	report of a case affecting a middle-age woman, 48, involving the e.n.t. area only. the aa comment on the features of the disease and report on the good results with medical treatment (prednisolone, indomethacin and dapsone).	2009	2655492
colony-stimulating factor and drug-induced agranulocytosis.		2008	2655524
colony-stimulating factor and drug-induced agranulocytosis.		2008	2655524
detection of vibrio vulnificus cytolysin in v. vulnificus-infected mice.	enzyme-linked immunosorbent assays using polyclonal and monoclonal antibodies specific for v. vulnificus cytolysin detected the toxin in an extract of skin lesions and in serum from mice showing local and systemic v. vulnificus disease after subcutaneous injection of the bacterium. the cytolysin also was detected in skin lesions by an indirect immunofluorescence procedure using polyclonal and monoclonal antibodies. our findings provide direct evidence that the cytolysin is produced in vivo durin ...	1989	2658204
pulsed-field gel electrophoresis of circular dna.	mobility of supercoiled (form i) and nicked circular (form ii) plasmid dnas was determined on two major forms of pulsed-field electrophoresis, chef and ofage. plasmids with molecular lengths ranging from 2.30 to 17.8 kilobase pairs (kb) were used with saccharomyces cerevisiae chromosomes as standards. agarose gel concentrations were varied from 0.3 to 2.0 percent, with higher percentage gels resolving forms i and ii of smaller plasmids. the pulsing range of 3.7 to 240 seconds resulted in quite v ...	1989	2662139
[the link between cholesterol and atherosclerosis: intervention trials].	intervention trials aimed at influencing the course of atherosclerosis by reducing blood cholesterol levels of two types: some of them evaluate the clinical consequences of atherosclerosis, while the others study the disease itself by means of arteriography. several trials of the first type have convincingly shown that the incidence of coronary disease decreases after at least 5 years of medicinal treatment. as for direct visualization trials, they seem to indicate that the development of athero ...	2009	2662362
thrombolytic therapy. a review (2).		2009	2663220
perspectives on the hallucinatory process.	hallucinations are common psychiatric symptoms and the hallucinating patient presents a number of nursing problems. although psychiatric nurses have written fairly extensively about hallucinations as a clinical problem, little nursing research has tested commonly recommended nursing interventions. this paper presents a review of interdisciplinary research on hallucinations and synthesizes findings with clinical observations to suggest a number of areas needing greater stress in nursing practice ...	2009	2663771
the history of responses to epidemic disease in the united states since the 18th century.	history offers some guidance for understanding social and policy responses to the aids epidemic. pertinent themes in the history of responses to epidemic disease in the united states in the past two hundred years include an initial underestimation of the severity of the epidemic; the prevalence of fear and anxiety; flight, denial, and scape-goating as a result of fear; efforts to quarantine and isolate carriers and the sick; the assertion of rational policies by coalitions of business, governmen ...	2009	2664485
review of cardiovascular findings in humans treated with minoxidil.	minoxidil is an antihypertensive vasodilator with no known capability of inducing human cardiovascular pathology; however, the compound does cause a late, canine-specific lesion of the right atrium and acute right atrial and ventricular papillary muscle changes. in all the autopsy cases of minoxidil-treated humans to date, 9 cases were reported with significant right atrial or other cardiac pathology and were carefully reviewed for similarity to either the early or late canine lesion. three new ...	1989	2665032
[conventional insulin therapy, infusion pumps, injector syringes. different methods of administration].		2009	2665113
vibrio vulnificus infection in hawaii.	a life-threatening vibrio vulnificus infection occurred in a 52-year-old korean woman with hepatic cirrhosis. four days after ingesting raw crab, the patient presented to the hospital with nausea, vomiting, fever, hypotension, and hemorrhagic blistering of the left foot. vibrio vulnificus was recovered from both her blood and a foot wound.	1989	2666323
neopterin measured in serum and tissue culture supernates by a competitive enzyme-linked immunosorbant assay.	in this solid-phase competitive enzyme-linked immunosorbant assay for neopterin (a product of activated macrophages) in serum or supernates of cell cultures, we incubate antiserum to neopterin with standards or samples in the presence of solid-phase-bound conjugate of carrier-neopterin. incubation with second antibody labeled with peroxidase then follows, before reaction with substrate. analytical recovery, precision, and sensitivity of this method are similar to those of other immunoassays. the ...	2006	2667801
rolipram in major depressive disorder: results of a double-blind comparative study with imipramine.	rolipram improves signal transmission in central noradrenergic neurones at a pre- and postsynaptic level, and is thus a novel approach in antidepressant therapy. in order to prove efficacy, tolerance, and safety, several controlled studies are underway. results of a randomized double-blind comparative trial versus imipramine involving 64 in-patients with major depressive disorder (dsm iii) in six independent centers will be presented and discussed. the chosen biometric model provided evidence th ...	2008	2668980
cannabis--its clinical effects.	the range of clinical, intoxicating, psychological and psychiatric effects of cannabis ('dagga') are reviewed. controversial subjects, such as the entities of toxic cannabis psychosis and the cannabis amotivational syndrome, are discussed.	2009	2669170
infectious and toxic syndromes from fish and shellfish consumption. a review.	primary care physicians care for large numbers of patients presenting with "food poisoning" or gastroenteritis. when a patient who presents with acute gastrointestinal illness, especially in conjunction with neurologic or cutaneous symptoms, is evaluated, the history should focus on past seafood consumption (particularly raw or undercooked seafood). the infectious syndromes are generally self-limited and respond to supportive care; exceptions are those caused by vibrio cholerae and vibrio vulnif ...	1989	2669661
therapeutic approaches for ophthalmic problems in juvenile rheumatoid arthritis.	juvenile rheumatoid arthritis is a disease of children which is chronic and painful, with the potential to produce permanent disability and blindness in a significant portion of cases. the treatment we provide these children may also disable them. managing this disease process and caring for these patients is a challenging task in which therapeutic efficacy must be continually balanced against treatment morbidity. with respect to ocular disease, we must particularly recognize the difficulties pa ...	2009	2672130
a new procedure for the targeted inactivation of essential bacterial genes.	a new method is described for the exchange of a plasmid encoded mutant gene with its chromosomal counterpart. the method is based on positive selection and is applicable for the exchange of essential genes. the main features of the method are: (1) cloning of an antibiotic resistance marker (without its promoter) downstream of the cloned target gene, thus forming an artificial operon; (2) inactivating the target gene (and consequently also the antibiotic resistance gene) by inserting a strong tra ...	1989	2674660
a new procedure for the targeted inactivation of essential bacterial genes.	a new method is described for the exchange of a plasmid encoded mutant gene with its chromosomal counterpart. the method is based on positive selection and is applicable for the exchange of essential genes. the main features of the method are: (1) cloning of an antibiotic resistance marker (without its promoter) downstream of the cloned target gene, thus forming an artificial operon; (2) inactivating the target gene (and consequently also the antibiotic resistance gene) by inserting a strong tra ...	1989	2674660
stereotactic evacuation of hypertensive cerebellar hemorrhage using plasminogen activator.	treatment for hypertensive cerebellar hemorrhage still remains controversial as to whether direct surgical procedure is indicated or not. this is so even after the introduction of ct scan which easily demonstrates the location and size of the hematoma and the presence of hydrocephalus. in this paper, we present our experience of 20 patients with cerebellar hemorrhage treated by stereotactic evacuation using komai's ct-stereotactic apparatus. all the patients had vertigo, cerebellar symptoms, dys ...	2009	2674756
a biotin-streptavidin amplified enzymeimmunoassay for 13,14-dihydro-15-keto-pgf2 alpha.	as an alternative for radioimmunoassays a new enzyme immunoassay (eia) for the determination of 13,14-dihydro-15-keto pgf2 alpha (pgfm) has been developed. biocytin was linked to pgfm by the n-hydroxysuccinimide method and the product (biocytinyl-pgfm) purified by reversed phase column chromatography. biocytinyl-pgfm was used in the eia as a bridge between the immobilized pgfm-antibody and streptavidin-peroxidase. the absolute sensitivity of the assay was about 160 amol (92% rel. binding) and re ...	1989	2675197
[airway epithelial function: its role in development of airway hyperreactivity].		2009	2675231
establishment and characterization of human glioblastoma cell lines in vitro and their xenografts in nude mice.	human gliomas were grown as permanent tissue cultures and xenografts in nude mice. growth kinetics, immunohistology and karyotypes were established. one tumor showed a distinct change in its karyotype after only two passages in nude mice; by contrast, no change of immunophenotype occurred during and after in vivo passaging. treatment of this glioma as xenograft in nude mice revealed a high sensitivity towards single agent treatment with bcnu. in view of the cytologic aberrations, however, this r ...	1989	2677876
marlene a. deluca (1936-1987).		2009	2678930
improvement in airway responsiveness and asthma severity during pregnancy. a prospective study.	in the myometrium and gut, smooth muscle becomes less contractile during pregnancy, probably because of the effect of progesterone and estrogen. it is not known whether these hormones cause similar changes in airway smooth muscle, and therefore, this study examined airway responsiveness during the large hormonal changes of pregnancy and evaluated whether changes in responsiveness are associated with changes in (1) progesterone and estrogen and (2) the clinical severity of asthma. twenty nonpregn ...	2008	2679270
design, methods, and rationale in the hypertension prevention trial. hypertension prevention trial research group.	the hypertension prevention trial (hpt) was a randomized, controlled, multicenter (four clinics, four resource centers) trial designed to test the feasibility of achieving and sustaining dietary changes in the intake of calories, sodium, and potassium and to assess the effect of those changes on blood pressure in a normotensive population. the trial involved 841 men and women (plus a test cohort of 78) who, at the first baseline (bl) examination, were in the age range of 25-49 years and had dias ...	2008	2680271
digit-muscle responses evoked from multiple intracortical foci in monkey precentral motor cortex.	1. the precentral motor cortex, including the anterior bank of the central sulcus of monkey (macaca fuscata), was systemically penetrated with microelectrodes to determine the spatial organization of the microexcitable cortical elements that can produce responses in digit muscles. 2. at 200-microns intervals on each electrode track, low-current intracortical microstimuli were delivered and the muscle responses evoked from four digit muscles were recorded. the responses, obtained with 5, 8, 15, a ...	1989	2681562
[poisoning by geromitra esculenta].	gyromitra esculenta (persoon ex fries) mushrooms have been responsible for severe intoxications and even deaths. clinical data are characterized primarily by vomiting and diarrhoea, and, afterwhile, by jaundice, convulsions and coma. the species of concern are mainly g. esculenta, g. fastigiata and g. gigas; nevertheless, recent advances in chromatography, biochemistry and toxicology have established that other species within the ascomycetes may prove also toxic. the toxins, i.e. gyromitrin (n-m ...	2009	2681713
fact and fashion: changing practices in child psychiatry.		2009	2681776
acute gluteal abscesses: injectable chloroquine as a cause.	one hundred and seven patients admitted to the casualty department with acute gluteal abscesses and surgically drained were studied. in 91 patients (85%) the abscess was a result of an intramuscular injection, of whom 71 patients (66%) had the abscess following a chloroquine injection (antimalarial). of those patients with an abscess following an intramuscular injection, in 64 patients (70%) a disposable syringe was used for injection of the drug and in 18% a boiled disposable was used. the inje ...	1989	2681814
high-frequency ventilation experience: a rescue protocol for neonates with airleaks.		2009	2681914
phosphoroselenoate oligodeoxynucleotides: synthesis, physico-chemical characterization, anti-sense inhibitory properties and anti-hiv activity.	oligodeoxynucleotides with a phosphorus atom in which one of the non-bridging oxygen atoms is substituted by selenium were prepared and investigated with respect to their antisense properties. a general synthesis of phosphoroselenoate analogs of oligonucleotides is described using potassium selenocyanate as the selenium donor. the compounds, characterized by 31p nmr, were shown to decompose to phosphate with a half-life of ca. 30 days. melting temperatures of duplexes between poly(ra) or poly(ri ...	1989	2682524
corticosteroids in homeostasis.		2008	2683585
corticosteroids in homeostasis.		2008	2683585
the common src homology region 2 domain of cytoplasmic signaling proteins is a positive effector of v-fps tyrosine kinase function.	a conserved noncatalytic domain sh2 (for src homology region 2) is located immediately n terminal to the kinase domains of all cytoplasmic protein-tyrosine kinases. we found that the wild-type v-fps sh2 domain stimulated the enzymatic activity of the adjacent kinase domain 10-fold and functioned as a powerful positive effector of catalytic and transforming activities within the v-fps oncoprotein (p130gag-fps). partial proteolysis of p130gag-fps and supporting genetic data indicated that the v-fp ...	1989	2685548
the common src homology region 2 domain of cytoplasmic signaling proteins is a positive effector of v-fps tyrosine kinase function.	a conserved noncatalytic domain sh2 (for src homology region 2) is located immediately n terminal to the kinase domains of all cytoplasmic protein-tyrosine kinases. we found that the wild-type v-fps sh2 domain stimulated the enzymatic activity of the adjacent kinase domain 10-fold and functioned as a powerful positive effector of catalytic and transforming activities within the v-fps oncoprotein (p130gag-fps). partial proteolysis of p130gag-fps and supporting genetic data indicated that the v-fp ...	1989	2685548
is there still a place for conjunctival-approach ptosis surgery?		2009	2687185
[principle, method, and application for the production of peptide hormones using genetic engineering].		1989	2691727
falciparum malaria--present day problems. an experience with 425 cases.	clinical details and present day problems encountered in 425 cases of falciparum malaria (pf) are reported. 10.11% had taken chloroquine prior to reporting to us. parasitic count done in 23.05% cases lacked correlation with severity of disease. pattern of fever varied markedly but 5.4% were afebrile throughout and presented only with bodyache and malaise. apyrexial spell was noted in 5.64%. 28.70% had typical facial looks of anaemia and sallow complexion. cerebral symptoms were noted in 3.05%. o ...	1989	2693436
vibrio vulnificus infection.	we report 3 cases of vibrio vulnificus infections from taiwan. patient 1, who manifested symptoms of primary septicemia, died after 2 days. patient 2, who had a wound infection and signs and symptoms of sepsis but negative blood cultures, responded to tobramycin and chloramphenicol plus surgical debridement, and recovered after 26 days of hospitalization. patient 3 had secondary septicemia originating from a wound inflicted by a shrimp. originally, the patient seemed to respond to ceftazidime an ...	1989	2694352
vibrio vulnificus septicaemia presenting as spontaneous necrotising cellulitis in a woman with hepatic cirrhosis.	vibrio vulnificus is a virulent marine organism commonly found in hong kong coastal waters which contaminates local sea-food. it may produce a primary septicaemia, often associated with secondary skin lesions, following ingestion of raw shell fish. we report a rapidly fatal case of primary v. vulnificus septicaemia in a 50-year-old housewife with post-hepatitic cirrhosis presenting as spontaneous necrotising cellulitis of the legs. v. vulnificus infection should be considered in patients with a ...	1989	2694353
parallels between neurasthenia and premenstrual syndrome.	neurasthenia and premenstrual syndrome became medical diseases because of the historical recognition of menstruation as a medical disease. both the nineteenth and twentieth century cultural views of women were important in the establishment of menstruation, neurasthenia and premenstrual syndrome as medical conditions. uncertainty of diagnosis with ever expanding diagnostic criteria, therapy undertaken without an adequate physiological basis, and often adverse effects from therapy, were character ...	1989	2694626
mechanism of lhrh-stimulated steroidogenesis in rat leydig cells: lipoxygenase products of arachidonic acid may not be involved.	luteinizing hormone releasing hormone agonist, [(imbzl)-dhis6,pro9,net]-lhrh (lhrh-a), caused a two to threefold increase in in vitro testosterone (t) secretion by rat leydig cells. this lhrh-a-induced t secretion was completely blocked by quinacrine and chloroquine, inhibitors of phospholipase a2. addition of phospholipase a2, however, was ineffective in stimulating basal or lhrh-a-induced t secretion. phospholipase c, on the other hand, significantly stimulated both basal and lhrh-a-induced t ...	1989	2695506
membrane fatty acid and virulence changes in the viable but nonculturable state of vibrio vulnificus.	the nonculturable state of vibrio vulnificus and, for comparison, that of escherichia coli were studied in artificial-seawater microcosms at 5 degrees c. total cell counts were monitored by acridine orange epifluorescence, metabolic activity by direct viable counts, and culturability by plate counts on selective and nonselective media. whereas total counts remained constant, plate counts of v. vulnificus suggested nonculturability by day 24. in contrast, direct viable counts indicated significan ...	1989	2696428
[a different view of sykstus lewkowicz].		2009	2698489
[ultrasonic diagnosis of tumorous lesions of the liver].		2009	2698513
evaluating the optometric literature: the educated clinician.	the purpose of this article is to present a framework for reader evaluation of optometric literature. the elements of a research article are outlined. suggestions are presented that clinicians can use to develop competence in evaluating research literature. also presented is an annotated bibliography of research references. better patient care and increased professional growth will result when clinicians evaluate and make use of the research literature.	2008	2703662
evaluating the optometric literature: the educated clinician.	the purpose of this article is to present a framework for reader evaluation of optometric literature. the elements of a research article are outlined. suggestions are presented that clinicians can use to develop competence in evaluating research literature. also presented is an annotated bibliography of research references. better patient care and increased professional growth will result when clinicians evaluate and make use of the research literature.	2008	2703662
[diagnosis and treatment of liver injuries and their sequelae].	the authors studied 222 cases of closed and open injuries to the liver and, in addition, had 5 patients who were treated for sequelae of injury (hemobilia, abscesses, biliary fistula of the liver). the diagnosis of open injuries to the liver is established without great difficulties; laparocentesis and laparoscopy are indicated in closed injury. the volume of the operation is determined by the character of the damage: closure of the hepatic wound proves sufficient in most patients; surgical debr ...	2009	2704167
the inspiring promise of dental implantology.		2009	2704492
effect of a high-fat meal on the bioavailability of a polymer-coated erythromycin particle tablet formulation.	the effect of food on the relative bioavailability of an erythromycin particles-in-tablet formulation was studied in 27 healthy volunteers, using a four-way, crossover study design with the following treatments: one or two erythromycin capsules usp (eryc, parke-davis), or one polymer-coated erythromycin particles-in-tablet (pce, abbott) administered fasting or with a high-fat meal. under fasting conditions the erythromycin particles-in-tablet and erythromycin capsule formulations are bioequivale ...	2009	2708552
ultrastructural analysis of axosomatic contacts on functionally identified primate spinothalamic tract neurons.	the morphology and frequency of axosomatic contacts on three functionally identified primate spinothalamic tract (stt) cells were analyzed at the electron microscopic level. the stt cells analyzed were wide-dynamic-range neurons responsive to activation of low- and high-threshold cutaneous afferents innervating the foot. the somas were located in the lateral border of lamina v; the dendritic trees were oriented dorsally and were very extensive. numerous spinelike appendages were observed emanati ...	2009	2708581
evaluation of infant feeding in acute gastroenteritis.	sixty-eight bottle-fed babies under 9 months of age with mild acute gastroenteritis were observed to evaluate current feeding regimens following acute gastroenteritis in infancy. all babies were fed for 24 h with a glucose-electrolyte mixture (gem) and then randomly assigned to either a gradual reintroduction to their normal milk, i.e., slow regrade; immediate return to full-strength formula; or a rapid regrade to a hypoallergenic whey hydrolysate formula. all groups were well matched for age, s ...	2009	2709254
how fast do very small abdominal aortic aneurysms grow?	fifty patients with abdominal aortic aneurysms from 2.5 to 5.0 cm in anteroposterior diameter (median 3.1 cm, mean +/- s.e. 3.3 +/- 0.1 cm) were initially offered non-operative treatment. two patients have subsequently undergone successful elective aneurysm resection because of increase in aneurysm size, and a third has died. the median annual growth rate of the aneurysm has been 0.22 cm and 77.8% increased in size between 6 monthly ultrasound examination. for aneurysms less than 4.0 cm the maxi ...	2009	2714450
proliferating giant pigmented nevus: a report of an unusual tumor occurring in association with a congenital giant pigmented nevus.	a 32-year-old japanese woman with a giant pigmented congenital nevus of the torso presented with a massive pigmented tumor mass of the vulva which grew over an 8-year period. histologically, the tumor was composed of benign appearing nevus-like cells with focal areas of extensive fibrous response. the tumor cells were positive for s-100 protein and with an antihuman melanoma antibody (moab 225, 28s) stain. electron microscopy confirmed the nevomelanocytic nature of the tumor cells and demonstrat ...	2009	2715665
vibrio vulnificus sepsis after eating raw oysters.	vibrio vulnificus, a marine vibrio found in coastal waters of the united states, may contaminate certain seafoods, particularly raw oysters. patients with underlying liver disease are particularly susceptible to severe illness. unexplained febrile diseases in patients who have eaten raw oysters may be caused by vibrio vulnificus. a fatal and a nonfatal case are reported in two such patients. these patients are the first two reported cases of vibrio vulnificus infection in kentucky.	1989	2723530
can the family physician avoid conflict of interest in the gatekeeper role? an affirmative view.		2000	2723596
how accurate are faculty evaluations of clinical competence?	to determine the degree and sources of variability faculty evaluations of residents for the american board of internal medicine (abim) clinical evaluation exercise (cex).	2009	2723833
characterization and purification of h1tf2, a novel ccaat-binding protein that interacts with a histone h1 subtype-specific consensus element.	definition of mechanisms regulating human histone h1 gene transcription during the cell cycle requires the isolation and biochemical characterization of protein factors which interact with specific promoter elements. two distinct binding activities have been identified in nuclear extracts from hela cells and mapped within a 180-base-pair (bp) region of a cell cycle-regulated h1 gene promoter. h1tf1 bound to an h1-specific a + c-rich sequence (ac box), 100 bp upstream of the cap site; h1tf2 inter ...	1989	2725515
primary structures of sm31/32 diagnostic proteins of schistosoma mansoni and their identification as proteases.	we have constructed cdna clones containing the complete nucleotide sequences coding for two highly antigenic schistosoma mansoni adult worm proteins, sm31 and sm32. the predicted amino acid sequence of sm31 shows significant homology to mouse, rat and human cathepsin b. the nucleotide sequence of sm32 is identical to that reported by others for s. mansoni "haemoglobinase'. the different nucleotide sequences demonstrate the existence of two different proteolytic enzymes, both of which are synthes ...	1989	2725581
low nanogram detection of nucleotides using fast atom bombardment-mass spectrometry.	the effect of trimethylsilyl (tms) derivatization on detection limits of mononucleotides in fast atom bombardment-mass spectrometry (fab-ms) was examined. fab-ms methods were developed to optimize sensitivity using adenosine 5'-monophosphate as a model compound and then applied to reference standards of two clinically important nucleotides: tricyclic nucleoside-5'-monophosphate (tcnmp) and 5-fluoro-2'-deoxyuridine-5'-monophosphate (fdump). the detection limit for the tms derivative of tcnmp was ...	2009	2729562
[the place of provisional tissues in the histologic classification, used for pedagogical purposes].		2009	2730350
3 drug management problems: cost, confusion, and adverse reactions.		2009	2733864
vibrio sepsis in a cirrhotic patient.	vibrio vulnificus should be suspected in any soft tissue infection occurring after exposure to the marine environment. early recognition followed by appropriate antibiotic therapy and debridement of involved tissue are essential features in the treatment of these infections.	1989	2734646
[the significance of the place of delivery and other factors for the course of breast feeding].	a prospective investigation of the course of delivery and postpartum period in the maternity clinic and special department in glostrup hospital was undertaken and data concerning establishing of breast feeding and its course were registered. in order to assess the significance of various factors for the course of breast feeding, two materials of 125 deliveries in the maternity clinic and 170 deliveries in the special department, respectively, were compared, all of which were characterized by unc ...	2009	2734905
[occupational diseases and their reporting].		2009	2734931
cyclosporine in behçet's disease resistant to conventional therapy.	cyclosporine (cyclosporine a) at 7 to 16 mg/kg/day was administered for eight to 18 months to four patients with behçet's disease with bilateral panuveitis resistant to the combination of prednisone, colchicine, and chlorambucil. visual acuity was maintained or improved in all eyes. color vision also improved significantly. a dramatic and significant decrease of the chronic vitreous haze occurred within the first two weeks of therapy and persisted until the end of the study. retinal inflammation ...	2009	2735696
mode of processing and hemisphere differences in the judgement of musical stimuli.	the relationship between processing strategy and ear asymmetry was examined in two experiments in which subjects were required to make judgements about monoaurally presented musical chords. in the first experiment, subjects without musical training showed a significant left ear advantage while in those with musical training a significant shift towards a right ear advantage was observed. performance on the embedded figures test (eft) suggested a strong relationship between analytic processing sty ...	2009	2736338
changing the school system.		2009	2738019
ventricular arrhythmias and local electrograms after chronic regional denervation of the ischemic area in the pig heart.	cardiac denervation has been proved to reduce the incidence of coronary occlusion arrhythmias in digs, but the effect of limiting the extent of sympathectomy to the ischemic area, particularly in hearts with sparse coronary collateral circulation, as in the human heart, needs further investigation. ventricular arrhythmias and changes in epicardial direct current electrograms induced during acute left anterior descending coronary artery occlusion were recorded in 14 pigs subjected to regional den ...	1989	2738265
role of technetium-99m phosphonate bone and indium-111 leukocyte scanning for detecting the infected hip prosthesis.		2009	2738681
[tumoral hypocalcemia].	hypocalcemia is a rare and not well understood paraneoplasic manifestation. we report the clinical case of a patient with hypocalcemia due to extensive osteoblastic metastasis. the corrected serum calcium levels for albumin was 7.2 mg/dl. calciuria was less than 10 mg/24 h. magnesium, phosphate and 25-hydroxyvitamin d levels were normal. pth and 1,25-dihydroxyvitamin d levels were increased. the pathogenesis of this disorder is possibly related to the massive calcium flow toward metastatic areas ...	2009	2740546
predictors of mortality and physical disability in the charleston heart study.		2009	2741270
[decreasing the emission of pollutants in laboratory waste water by substitution of trichloromethane].	working up great test series to determine chloroform-extractive substances and tensides, increased trichlormethane concentrations can appear in the laboratory air-inspite of realization of numerous precautionary measures. as a rule the makd rate will be exceeded than. various precautions failed to fulfill their purpose so that the solvent trichlormethane had been replaced by other solvents. two demands mainly influenced on this replacement. the risk to health must be decreased so far that the wo ...	2009	2741501
lack of nephrotoxicity of styrene at current tlv level (50 ppm).	biochemical markers of kidney damage were examined in 37 female workers exposed to an average concentration of 225 mg/m3 of styrene. the concentration of mandelic acid in urine was on the average 759 mg/g creatinine. the mean duration of employment of the exposed subjects was 11 years. the results were compared to those obtained in 35 control female workers matched for age and a number of demographic and lifestyle factors and with no history of exposure to organic solvents. no difference was fou ...	2009	2744872
the importance of previous convictions in assessing criminal motivation--the need for detail.	full details of an offender's previous convictions are not customarily available to those who have to try to predict the possibility of future dangerous behaviour. it is suggested that such information might enhance the quality of prediction; some illustrations are offered in support of this contention.	2009	2747471
pilomatrix carcinoma: role played by mr imaging.	we report the magnetic resonance imaging (mri) of a pilomatrix carcinoma. we found a soft tissue tumor of the back entering the spinal canal and compressing the spinal cord and we monitored a good response to radiotherapy and chemotherapy. we have concluded that mri played an important role in determination of the volume, extension and management of this rare malignant tumor.	2009	2747902
phase i study of a new antianxiety drug, buspirone.	1. a phase i study of buspirone was conducted in 7 healthy male volunteers. 2. diazepam was selected as the control drug and administered in equipotent doses to buspirone. dosage was initiated at 2.5mg and doubled until a maximum dosage of 20mg was attained. subsequently, 10mg was administered once a day for three consecutive days. 3. clinico-pharmacologically both drugs produced sleepiness/drowsiness, but dizziness, light-headed feeling and feeling of drunkenness were marked only in the diazepa ...	2005	2748857
[complexing of bovine serum albumin with phosphatidyl choline liposomes].	thermodynamic parameters of the bovine serum albumin interaction with phosphatidyl choline liposomes have been determined. it is shown that the bovine serum albumin is adsorbed on the liposomal surface without change of the globule conformation, the polar interactions making dominant contribution in immobilization. the complexing is characterized by a binding constant and a great number of binding sites.	1989	2749908
mass treatment approach to acute diarrhoeal disease in afabet hospital, northern ethiopia.	during an outbreak of acute diarrhoeal disease in a military camp in afabet region from august to october 1985, 416 cases were admitted to afabet hospital. all were national military service recruitee males who developed signs of moderate to severe dehydration. simplified methods of diagnosing and treating the disease were used so that mass rehydration therapy could be instituted early, using locally available manpower and material resources. the severity of dehydration was graded, and rehydrati ...	2009	2753031