Publications

[identification of camp dependant protein kinases in human lymphocytes].	chromatographic purification by "deae" cellulose resolves the camp binding proteins in human lymphocytes into three parts. in presence of mg++ each one possesses camp dependent protein-kinase activity, one of them showing allosteric characteristics.	1975	172248
[resistance to association of antibiotics (polymyxin and penicillin) in relation to cell concentration of two bacterial species in the same inoculum. complementary inoculum effect].	dense suspensions of sa. typhi (polys penr) and of st. aureus (polyr pens) proliferate on gelose medium added with the two antibiotics only if the inoculum is mixed. the growth is probably due to the partial neutralization of the antibiotics following the formation of complexes between these antibiotics and some constituents of the two strains.	1975	172250
magnesium inositol hexaphosphate deposits in mesozoan dispersal larvae.		1988	172340
hormonal regulation of glycogen metabolism in human fetal liver. i. normal development and effects of dibutyryl cyclic amp, glucagon, and insulin in liver explants.	glycogen accumulates in human fetal liver beginning at the eighth week of gestation. a parallel increase in total glycogen synthase activity is found, although the i-form activity remains low and constant throughout the first two thirds of gestation. total phosphorylase activity increases slightly during this period, with the proportion in the active form amounting to about one half of the total throughout. after an initial rapid decline, the glycogen concentration in explants of human fetal liv ...	1975	172397
plasma adrenocorticoid response to corticotropin in dairy cattle fed high silage diets.	responses of plasma corticoids to adrenocorticotropic hormone (.32 u/kg body weight) administered during early lactation were measured in dairy cattle consuming large amounts of concentrate feeds and one of the following forage diets: alfalfa-timothy hay plus corn silage, alfalfa-timothy hay crop silage plus corn silage, or corn silage. concentrations of plasma corticoids increased to maximum in all groups within 60 to 90 min. concentrations remained at near maximum for 4 to 5 h and then decline ...	1975	172536
profile of a continuing care program emphasizing discharge planning.		1989	172615
effects of quantity and quality of dietary protein and variation in certain enzyme activities on glucose metabolism in the rat.	this study attempted to determine whether the quantity and the quality of protein intake could influence the activity of some enzymes involved in carbohydrate metabolism. thus, adult rats were fed for 23 days a diet containing different levels (10 to 70%) and qualities (casein, wheat gluten, and egg yolk) of protein. variations in liver enzyme activities of pyruvate kinase (pk), glucose-6-phosphate dehydrogenase (g6pdh), malic enzyme (me), glucose-6-phosphatase (g6pase), and phosphoenolpyruvate ...	1975	172617
distribution of membrane-bound cyclic amp-dependent protein kinase in plasma membranes of cells of the kidney cortex.	renal cortical plasms membranes were separated by free flow electrophoresis into luminal (brush border microvilli) and contraluminal (basal-lateral membrane) fractions. these membranes were found to contain an intrinsic, self-phosphorylating system which consists of a cyclic amp-dependent protein kinase, a phosphorprotein phosphatase and the substrate(s) of these enzymes. the kinase, but not the phosphatase, was stimulated by cyclic amp; maximal (1.7-fold) stimulation was effected at a cyclic am ...	1975	172638
properties of the escherichia coli dna-binding (unwinding) protein interaction with nucleolytic enzymes and dna.		1975	172646
molecular structures of cytidine-5'-diphosphate and cytidine-5'-diphospho-choline, and their role in intermidiary metabolism.	the nucleotide coenzyme cytidine-5'-diphospho-choline is highly folded. the cmp-5' parts of the molecules in the crystal structure are strongly linked by metal ligation and hydrogen bonds leaving the phosphoryl-choline residues relatively free. cytidine-5'-diphosphoric acid exists as a zwitterion with n31 protonated. the p-o bond lengths from the anhydride bridging oxygen in the pyrophosphate are significantly different.	1989	172799
[virus inhibition using hesperidin].		1989	172802
stimulation of cholesterol ester exchange by lipoprotein-free rabbit plasma.	a fraction in normal and hypercholesterolemic rabbit plasma of density greater than 1.25 stimulates the exchange of cholesterol esters between very low density and low density lipoproteins from hypercholesterolemic rabbit plasma. the exchange does not result from lecithin:cholesterol acyltransferase activity. the active factor appears to be a high molecular weight globulin with an isolelectric point of 5.2.	1975	173390
lysine-sensitive aspartate kinase of serratia marcescens.		1975	173646
[state of the horns in cattle in the normal state and in deformations].		1975	174276
letter: liver tumours and the pill.		1987	174777
perianal paget's disease: report of seven cases.		1987	174872
[new protein-free film method for electron microscopy of dna].		1987	174876
a receptor site for prolactin in lactating mouse mammary tissues.	prolactin iodinated by lactoperoxidase method showed immunologically, electrophoretically and biolo9gically similar properties to native prolactin and possessed enough specific radioactivity for receptor studies. 1251-prolactin was incubated with mouse mammary tissues at 8 days of lactation. both binding and release of 1251-prolactin depended on incubation time and temperature and were maximal at 37 degrees c. michaelis constant was estimated to be 1.4 x 10(-9) m from lineweaver-burk plot and to ...	1975	174901
prosthetic restoration in congenital lower limb deficiency. a case study.	we presented a synopsis of a young girl with congenitally deficient limb who underwent seven corrective surgical procedures and fabrication of a specially designed and constructed prosthesis. the surgical procedures are detailed as in the total rehabilitation approach. we have provided plastic laminated orthoses and prostheses to many patients with congenitally deficient upper and lower limbs. an additional paper will detail our experience with a series of plastic laminated orthoses and prosthes ...	1988	175872
[pathogenic and therapeutic concepts in viral hepatitis].		1976	175890
ultrastructural surface alterations of serratia marcescens after exposure to polymyxin b and/or fresh human serum.	exposure of serratia marcescens cells to 10, 5, and 2.5 mug/ml of polymyxin b resulted in outer cell surface alterations that consisted of coarse, pleomorphic projections which revealed a double-contoured membrane structure. in contrast, fresh, but not heat-inactivated human serum caused the deposition of very fine, thread-like aggregates on the outer cell surface of exposed cells. the combination of polymyxin b and fresh human serum caused clearly discernible ultrastructural changes of the poly ...	1976	176013
norepinephrine-induced shift in levels of adenosine 3':5'-monophosphate and atp parallel to increased respiratory rate and lipolysis in isolated hamster brown-fat cells.	1. isolated brown fat cells from hamster respond to added catecholamines with a temporary increase in respiratory rate and an extended lipolysis. 2. from experiments with catecholamines and alpha and beta-blockers, the receptors of these cells are classified as beta according to classical definition. 3. norepinephrine induces a rapid increase in adenosine 3':5'-monophosphate levels which parallels in time the stimulated respiration. maximal adenosine 3':5'-monophosphate levels are reached within ...	1988	176028
effects of cholera enterotoxin, glucagon, and dibutyryl cyclic amp on rat liver alkaline phosphatase, bile flow, and bile composition.	cholera enterotoxin, 45 mug per 250 g body weight, administered intravenously to rats, caused a 6-fold rise in the activity of liver alkaline phosphatase in 12 hr. there was no change in bile volume or in the concentration or total bile content of na+, k+, hco3-, or cl- for 36 hr after the administration of cholera toxin. however, bile phospholipid output fell markedly from a control level of 15.0 +/- 1.0 mumol per 6 hr to a low level of 4.0 +/- 1.2 mumol per 6 hr in the 12- to 18-hr collection, ...	1976	176082
use of horseradish peroxidase to study the antagonism of clostridium welchii (cl. perfringens) type d epsilon toxin in mice by the formalinized epsilon prototoxin.		1976	176185
release of xenotropic type c rna virus in response to lipopolysaccharide: acitivity of lipid-a portion upon b lymphocytes.	the present studies demonstrate that lipopolysaccharide (lps) causes the release of endogenous xenotropic type-c rna virus from balb/c spleen cells. the evidence suggests that virus release is stimulated by the lipid-a portion of lps and primarily involves an action of lps on b lymphocytes. lps had little or no effect on virus release by t lymphocytes, macrophages, or fibroblasts. these results indicate that the differentiated state of the cell plays an important role in the regulation of endoge ...	1976	176273
cells isolated from trypsin-treated brain contain trypsin.		1976	176319
international trends.		1985	176353
growth in semisolid agar medium of human cord leukocytes freshly transformed by epstein-barr virus.	the semisolid agar method for the selective growth of transformed cells was applied to investigations of epstein-barr virus (ebv) transformation. when 1 x 10(5) human umbilical-cord blood leukocytes were seeded in agar medium immediately after ebv exposure, about 100 colonies developed in each dish. the occurrence of colonies correlated well with dilutions of ebv inoculum. these colonies were composed of lymphoblasts, were positive for ebv-determined nuclear antigen immunofluorescence, and cons ...	1976	176377
regression of established tumors and induction of tumor immunity by intratumor chemotherapy.	the inoculation of a mixture of drugs and guinea pig hepatoma cells (line-10) induced tumor-specific immunity in about 20% of guinea pigs. when guinea pigs with established intradermal tumors were given various drugs ip, no cures were observed; in contrast, multiple intralesional injections of actinomycin d, 1,3-bis(2-chlorethyl)-1-nitrosourea, adriamycin, mitomycin c, and melphalan were effective in curing animals of their intradermal tumors at a time when there were tumor cells in the draining ...	1976	176411
on the question of the ultrastructure and composition of corpus intra cristam after local methylcholanthrene application.		1986	176418
[environmental hazards in the hospital, as examplified by hospitalismus].		1986	176519
adenylate cyclase and catecholamine binding in plasma membrane-enriched preparations of cardiac and skeletal muscle.	binding of [3h] epinephrine to plasma membrane-enriched fractions from guinea pig heart and rabbit skeletal muscle was investigated using the micropore filtration technique. [3h] epinephrine and [3h] norepinephrine were found to be degraded rapidly in aqueous buffer at ph 7.6 and 37 degrees c. deterioration of the compounds could be prevented by low concentrations of dithiothreitol. binding of [3h] epinephrine to both membrane preparations was a slow process requiring 60 min to approach equilibr ...	1976	176693
[obtaining the beta-globulin fractions from swine and cattle sera and a study of their immunological activity].	the rivanol precipitation was used to obtain beta-globulin fractions from specific swine sera against edema disease, paratyph and aujeszky's disease as well as from normal ovine and swine sera. agar electrophoresis revealed that the preparations produced contained beta-globulin (86 per cent), gamma-globulin (5 per cent), and alpha2-globulin (9 per cent). the beta-globulin preparations were studied for the presence of antibodies against e. coli, salmonellae, staphylococci, myxovirus parainfluenza ...	1976	176771
[synthesis of virus-specific macromolecules and virion maturation in chick embryo cells infected with sendai virus].	synthesis and accumulation of virus-specific rna, proteins and intracellular nucleocapsids are observed in sendai virus-infected chick embryo cells for approximately 2 days postinfection. however, only an insignificant part of these products leaves the cell as a result of maturation of virus particles. it is suggested that the cause of the ineffective maturation of virions in the system under study may be in the observed instability of one of virus structural proteins in the infected cells, m pr ...	1976	176819
use of sodium polyanethol sulfonate to selectively inhibit aminoglycoside and polymyxin antibiotics in a rapid blood level antibiotic assay.	sodium polyanethol sulfonate inhibits aminoglycoside and polymyxin classes of antibiotics in direct proportion to its concentration. aminoglycoside and polymyxin class antibiotics are selectively inactivated; penicillin, including the semisynthetic penicillins, cephalothin, chloramphenicol, clindamycin, tetracycline, erythromycin, and vancomycin are not inhibited. by incorporating sodium polyanethol sulfonate directly into the test medium it is possible, in a 4-h antibiotic blood level assay, to ...	1995	176933
effects of potassium chloride and smooth muscle relaxants on tension and cyclic nucleotide levels in rat myometrium.	ten minutes after kcl-depolarization of rat myometrial strips, at which time the muscles were in a state of sustained contracture, tissue levels of adenosine 3',5'-cyclic monophosphate (cyclic amp) were increased by approximately 40% over relaxed controls, and levels of guanosine 3',5'-cyclic monophosphate (cyclic gmp) were decreased by 40%. at this point both nitroglycerin (4 x 10(-4) m) and papaverine (2 x 10(-5) m) were capable of relaxing the depolarized muscles without significantly increas ...	1975	177160
hepatomas in grs/a male mice treated with horse serum or horse anti-mouse antilymphocyte serum.		1976	177290
investigations into the mechanism of reduction of ethanol sleep by thyrotropin-releasing hormone (trh).	thyrotropin-releasing hormone (trh), administered intraperitoneally, was found to antagonize ethanol-induced sleep and hypothermia in mice without affecting brain ethanol content. this reduction of the actions of ethanol was also apparent after oral or intracisternal administration of trh. in addition, trh reduced ethanol-induced sleep in rats, hamsters, gerbils and guinea pigs. evidence that the pituitary-thyroid axis is not necessary for the effects of trh was provided by observations that hyp ...	1976	177753
the therapeutic community and the nurse: a blurring of traditional roles.		1996	177765
dichloromethane produces narcotic effect.		1996	177918
sulfamethoxazole-trimethoprim-polymyxin therapy of serious multiply drug-resistant serratia infections.	nonpigmented multiply drug-resistant serratia marcescens caused an extensive outbreak of infection at the nashville veterans administration hospital. isolates were of one serotype resistant to all currently available antimicrobial agents for therapy of systemic infections except for occasional susceptibility to chloramphenicol and kanamycin. frequently strains were susceptible to nalidixic acid, and all were susceptible to amikacin (bb-k8). drug-resistant strains caused 130 infections, 12 bacter ...	1976	178273
[traumatic deciduoma and delayed nidation in castrated pregnant rat after acth injection].	after administration of acth it is possible to obtain traumatic deciduomata in rats ovariectomized during early pregnancy and delayed implantation in rats ovariectomized day 4 of pregnancy and injected dayly with oestradiol from day 8 or 9. the substance responsible seems to be progesterone or progesterone like corticoid.	1975	178414
evidence of methylation of b77 avian sarcoma virus genome rna subunits.	b77 avian sarcoma virus rna was labeled with (methyl-3h) methionine under conditions that prevent non-methyl incorporation of 3h radioactivity into purine rings. from the determined values for the extent of methylation of 4s rna isolated from infected chicken embryo cells, it was estimated that 30 to 40s rna subunits that results from heat denaturation of the 60 to 70s rna contain approximately 21 methyl groups, of which 14 to 16 are present at internal positions as n6 -methyladenosine residues. ...	1976	178899
studies on the inhibitory activities of human serum lipoproteins for japanese encephalitis virus.	human serum lipoproteins were purified by ultracentrifuging and their concentrations adjusted as required to be within the normal male/female serum range for all assays. the activities in inhibition of hemagglutination (hai) for japanese encephalitis virus were--low density lipoprotein (ldl) greater than very low density lipoprotein (vldl) greater than high density lipoprotein (hdl). heating (56 degrees c/30 minutes) caused the ldl titer to fall and freeze-thawing (20 degrees c/room temperature) ...	1975	179150
an experimental model for disseminated herpesvirus infection of the neonate.	pregnant mice at 10 days of gestation were more susceptible to vaginal inoculation with herpesvirus, type 2, than were nonpregnant mice. this mouse model system also was used to compare delivery through a birth canal contaminated with herpesvirus, type 2, to delivery after maternal paranteral inoculation by the same virus. approximately 26 per cent of newborn mice either died or had evidence of disseminated herpesvirus infections after delivering through a vagina inoculated with herpesvirus, whe ...	1976	179321
the grooves of the distal articular surface of the femur-a normal variant.		1997	179342
optimum conditions for the binding of insulin to its receptor.	the specific binding of insulin to the membranes from lactating mouse mammary gland was studied as a model of hormonereceptor type of binding. the basic ingredients of binding, the concentration of receptor protein and the concentration of labeled insulin were mainly studied. the characteristic changes in specific binding were followed, the adequate regression equation was draen and the optimum conditions of binding were established for further experiments. the expediency of applying shortened o ...	1976	179574
technetium-99m labelled imidodiphosphate: an improved bone-scanning radiopharmaceutical.	technetium-99m labelled imidodiphosphate was prepared in the presence of stannous ions. it was evaluated as a bone-scanning agent in animals and patients. comparative tissue distribution studies in mice showed a relatively higher uptake of radioactivity in bone when 99tcm -labelled pyrophosphate and diphosphonate. accumulation of radioactivity in soft tissues, especially kidneys, was less with this radiopharmaceutical. results in patients were most satisfactory in delineating skeletal bone and i ...	1976	179654
[herbs with vitamin d effect (author's transl)].		1997	179713
steroid production by quartered and capsular rat adrenal gland in response to haemorrhage.	60 min after rapid bleeding (1.5--2.0 per cent of b. w.) both aldosterone and corticosterone production rate by quartered rat adrenals were found to be elevated. however, no difference was observed in the rate of aldosterone and corticosterone production by capsular adrenals of sham operated and hypovolaemic rats. corticosterone production rate by decapsulated adrenals was much more higher after haemorrhage than in the control group. the same alterations could be observed incubating adrenal tiss ...	1975	179800
cytokinin ocntents and camp metabolism during growth of escherchia coli.	during escherichia coli growth, we found an inverse correlation between free cytokinin content and camp level. the rates of synthesis of adenylate-cyclase and camp-phosphodiesterase were practically constant.	1976	179840
[changes in the functional state and structure of the adrenals in cc14 poisoning].	introduction of cci4 in doses of 0.1 and 0.2 ml/100 g to albino rats reduced the steroid production generated by adrenal sections. in 24 and 48 hours after poisoning with a small dose of cci4 (0.1 ml/100 g) there could be seen an increased concentration of 11-oxycorticosteroids in the plasma. morphological signs of a damage suffered by the gland were observed only in poisoning with a large dose of cci4 (0.2 ml/100 g).	1975	179852
lipid-protein interaction in porcine high-density (hdl3) lipoprotein.		1975	179867
nad+-malic enzyme. regulatory properties of the enzyme from ascaris suum.	the regulatory properties of the nad-dependent malic enzyme from the mitochondria of ascaris suum have been studied. the malate saturation curve exhibits sigmoidicity and the degree of this sigmoidicity increases as the ph is increased. fumarate was the only compound tested that stimulated the enzyme activity, whereas oxalacetate was the most powerful inhibitor. activation by low levels of fumarate was found to be competitive with malate. it is proposed that this stimulation has physiological si ...	1976	180002
stimulation of ornithine decarboxylase synthesis and its control by polyamines in regenerating rat liver and cultured rat hepatoma cells.	ornithine decarboxylase has been induced in log phase hepatoma cells grown in suspension culture. induction with n6, o2'-dibutyryl cyclic adenosine 3':5'-monophosphate produced a 4-fold increase in enzyme activity by 3 hours which was followed by a return to base levels by 6 hours. induction with dexamethasone, a potent synthetic glucocorticoid, exhibited a slow steady rate of increase in enzyme activity, reaching a plateau level of approximately 5- to 6-fold stimulation by about 12 hours. indu ...	1976	180026
study of title 19 (medicaid) coverage of sterilization.		1985	180077
in vivo reversal of thyroxine induction of dna synthesis by dibutyrly cyclic amp in developing rat cerebellum.	thyroxine, dibutyryl cyclic amp, and a combination of both drugs were administered daily from birth to 2, 2 and 3 pups, respectively from each of 5 litters of sprague-dawley rats. body weight, brain weight, cerebellar weight, and cerebellar dna were measured in each animal at age 5 days and compared with values from a pair of controls from each litter. cerebellar weight and dna content were affected more severely than body weight in cyclic amp-treated animals, with cerebellar dna reduced signifi ...	1976	180263
uptake of circulating iron by the duodenum of normal mice and mice with altered iron stores, including sex-linked anemia: high resolution radioautographic study.	using electron microscopy radioautography, the deposition of intravenously administered iron in the duodenal epithelium was studied in normal mice, iron-overloaded and iron-deficient mice, and in mice with x-linked anemia (gene symbol sla) 4 and 24 hours after injection of 59fe. the resolution of radioautography with 59fe was determined with a line source and the distance from the hot line within which half of the grains fell (hd value) was 1650 a. in normal, iron-overloaded, and sla mice, radio ...	1985	180329
experimental alterations in cyclic adenosine monophosphate concentrations in the cat basilar artery.	levels of cyclic adenosine monophosphate (amp) in the basilar artery and in circulating blood of cats were determined after the production of spasm by topical application of blood to the vessel and following treatment with agents known to alter cyclic amp. isoproterenol, known to stimulate adenyl cyclase, and aminophylline, a phosphodiesterase inhibitor, were studied alone and in combination. cyclic amp of the basilar artery fell from a mean control value of 43 to 26 pmoles per milligram of prot ...	1976	180456
serum testosterone and dihydrotestosterone in patients with trophoblastic disease.	serum testosterone (t) and dihydrotestosterone (dht) were measured by radioimmunoassay in 14 patients with unaborted hydatidiform mole and in 16 patients with normal pregnancy of similar gestational age. serum human chorionic gonadotropin (hcg) was measured by the radioreceptor assay in patients with hydatidiform mole. serum t ranged from 0.27 to 5.39 ng/ml with a mean +/- se of 2.21 +/- 0.45 ng/ml in patients with hydatidiform mole mole and from 0.20 to 2.40 ng/ml with a mean +/- se of 0.80 +/- ...	1976	180465
calcium-binding protein and calcium absorption in the laying quail (coturnix coturnix japonica).	a vitamin d3-dependent calcium-binding protein (cabp) has been found in the intestinal mucosa of japanese quail (coturnix coturnix japonica). this protein is similar, if not identical to that of the chick (gallus domesticus). a similar protein fraction appears also in uterine mucosa of laying quail. both intestinal and uterine cabp levels are higher in laying than in non-laying quails. uterine cabp was higher during egg shell formation than during uterine inactivity. the slight corresponding dif ...	1976	180508
the influence of potassium and acth on plasma-aldosterone regulation in anephric patients.	after increasing the intracellular potassium concentration of seven anephric patients without changing the total body potassium, by administration of insulin-glucose, the plasma-aldosterone concentration increased significantly to 180 percent of the pre-infusion value despite a drop in plasma potassium. a significant correlation between the decrease in the plasma potassium and the increase in plasma aldosterone concentration was found. plasma cortisol remained unaffected. acth stimulation of fiv ...	1986	180522
a fatty acyl-coa oxidizing system in rat liver peroxisomes; enhancement by clofibrate, a hypolipidemic drug.	purified rat liver peroxisomes contain a cyanide-insensitive fatty acyl-coa oxidizing system that uses o2 and nad as electron acceptors. the system was detected by the ability of added palmitoyl-coa to elicit o2 consumption, h2o2 production, and o2-dependent nad reduction. the activity of this system is increased approximately one order of magnitude in rats treated with clofibrate, a hypolipidemic drug known to cause peroxisomal proliferation.	1976	180535
[goodpasture's syndrome. apropos of a case associated to a hepatocarcinoma].		1986	180568
[binding to chicken liver lactatedehydrogenase (author's transl)].	some information about the lactate dehydrogenase nad binding site has been obtained by working with coenzymes analogs of incomplete molecules. 5'amp, 5'-adp, atp, 5'-c-amp and 3'(2)-amp inhibit chicken liver ldh activity competitively with nadh. 5"-amp and 5'-adp show a stronger inhibition power than atp, suggesting that the presence of one or two phosphate groups at the 5' position of adenosine, is essential for the binding of the coenzyme analogs at the enzyme binding site. ribose and ribose-5 ...	1976	180571
[epidemiological aspects of cytomegalovirus infections].		1975	180573
characterization of a nosocomially significant, multiple drug-resistant strain of serratia marcescens.	a multiple drug-resistant strain of serratia marcescens (bacteriocin type 18) was isolated from three clinical patients. the isolates were found to carry a conjugally nontransferable, nonmobilizeable resistance plasmid (r-plasmid) with resistance-(r)-determinants against ten antimicrobial drugs: ampicillin, carbenicillin, chloramphenicol, gentamicin, kanamycin, neomycin, streptomycin, tobramycin, triple sulfonamides, cotrimoxazole, and--possibly--nalidixic acid, as determined with exposure to 'c ...	1976	181215
stimulation of lymphocyte proliferation by killed mycobacteria and other bacterial species.	killed mycobacteria and some mycobacterial fractions induced spleen cells from normal c3h mice to incorporate tritiated thymidine to a relatively high degree. thymocytes under the same conditions were not activated. however, incorporation of thymidine was significantly increased when mixtures of thymus and spleen cells were cultured in the presence of the inducers. a similar activation of spleen cells was displayed in the presence of gram-positive and gram-negative non-mycobacterial species.	1976	181325
in vivo activation by polymyxin b of phospholipase from pseudomonas aeruginosa and escherichia coli.		1976	181357
proteoglycan complexes from bovine heart valve. fractionation by density-gradient centrifugation and gel filtration under dissociative conditions.	proteoglycan complexes from collagenase [ec 3.4.24.3]-indigestible materials of bovine heart valves were extracted with 4 m guanidinium chloride, purified by ion-exchange column chromatography in a urea-containing solution, then fractionated by density-gradient centrifugation under dissociative conditions. electrophoretic characteristics and enzymic susceptibility of the density-gradient fractions revealed that the glycosaminoglycans constituting the proteoglycan complexes in this indigestible m ...	1976	181367
thyroid antigen stimulates lymphocytes from patients with graves' disease to produce thyroid-stimulating immunoglobulin (tsi).	circulating lymphocytes from patients with graves' disease and from control subjects were cultured in vitro alone, with normal human thyroid tissue homogenates, and with other nonthyroid human tissue homogenates. the supernatants of these cultures were assayed for human thyroid-stimulating activity by incubation with human thyroid slices in which increases in camp levels were then measured. human thyroid stimulator activity was demonstrated in 16 out of 20 experiments in which lymphocytes from p ...	1976	181397
thyroid peroxidase, thyroglobulin, camp and dna in human thyroid.	tissues from normal thyroid, euthyroid multinodular goiter, toxic goiter, hashimoto's thyroiditis, thyroid adenoma, and carcinoma were examined for their content of deoxyribonucleic acid (dna), thyroid peroxidase activity (tpa), thyroglobulin (tg), and adenosine 3',5'-cyclic monophosphate (camp). compared with normal thyroids dna was increased in the neoplastic tissues and decreased in euthyroid multinodular goiter. quantitative changes of thyroglobulin were observed, especially in the thyroid t ...	1976	181398
structure of herpesvirus saimiri genomes: arrangement of heavy and light sequences in the m genome.	herpesvirus saimiri contains two species of dna molecules. (i) the m genome is composed of 70% light (l) dna (36% cytosine plus guanine; density in cscl, 1.695 g/ml), which consists of unique sequences, and 30% heavy (h) dna (71% cytosine plus guanine; density, 1.729 g/ml). (ii) the h genome contains heavy sequences exclusively. h sequences in m and h genomes cross-hybridize completely and are cleaved identically by restriction endonuclease r-sma i into four classes of fragments with molecular w ...	1976	181593
neoplasia at the site of ureterosigmoidostomy.	an increased incidence of neoplasia at the site of ureterosigmoidostomy must be considered in patients being evaluated for or who have undergone this procedure. a case of mucinous adenocarcinoma 24 years following bilateral ureterosigmoidostomy is reported. this patient had bilateral hydroureteronephrosis, which led to left nephroureterectomy and right cutaneous ureterostomy. mucinous adenocarcinoma was diagnosed only after the edematous, protruding and inflamed cutaneous ureterostomy stoma was ...	1981	181600
the actions of parathyroid hormone on bone: relation to bone remodeling and turnover, calcium homeostasis, and metabolic bone diseases. ii. pth and bone cells: bone turnover and plasma calcium regulation.	kinetic and morphologic studies in patients with parathyroid disease, and a wide variety of studies in experimental animals indicate that one major effect of pth is to increase the proliferation of osteoprogenitor cells into osteoclasts and so to increase bone turnover. pth stimulates bone cells by increasing cell membrane permeability to calcium and consequently increasing calcium influx and by activating membrane-bound adenyl-cyclase. it is likely that the former event precedes the latter and ...	1981	181659
[the character of the distribution of chloroplast dna from higher plants in a cesium chloride density gradient].	the nature of distribution of the chloroplast dna from three species of higher plants (sp. oleracea, n. tabacum, p. sativum) in the cscl density gradient has been investigated dna preparations isolated from the fractions of chloroplasts completely deprived of the admixtures of nuclei and mitochondria are characterized by symmetric distribution in the density gradient. fragmentation of chloroplast dna of higher plants is not accompanied by the appearance of the discrete satellite components. it h ...	1981	181670
factors influencing the size, composition and metabolism of very low density lipoproteins in the rat.		1976	181699
an unusual upper abdominal gas pattern.	the case history of one patient is discussed to illustrate radiographic features, etiology and prognosis of gas bubbles in the gastric wall.	1981	181780
a protein-binding assay for direct determination of adenosine 3',5'-monophosphate in amniotic fluid, cerebrospinal fluid, plasma, and urine.	an adenosine 3',5'-monophosphate (cyclic amp)-binding protein was isolated from bovine skeletal muscle. this preparation showed maximum binding capacity for cyclic amp at the physiological ph of amniotic fluid, cerebrospinal fluid, and plasma and had a high association constant of 1.4x10(9) 1/mol. this preparation of binding protein, together with albumin and edta in the assay buffer, gave a sensitive and specific competitive protein-binding assay that permitted direct determination of cyclic am ...	1976	181838
enzootic with ectromelia symptomatology in sprague-dowley rats.		1976	181904
binding of digitoxin and digoxin to normal human beta-lipoproteins.		1976	181946
a variant of poland syndrome: report of case.	a variant case of poland syndrome is reported, with the patient presenting major unilateral anomalies in the sternocostal head of the left pectoralis major muscle and a shorter left arm and hand. no pre-natal history of attempted abortion or using toxic or teratogenic drugs could be elicited. the variability of the upper extremity anomalies and the frequency of major ipsilateral defects of the skeletal and genite-urinary systems, the associated diseases, and the diagnosis and management of these ...	1982	181952
familial syndrome with dystonia, neural deafness, and possible intellectual impairment: clinical course and pathological findings.		1982	181965
specific modification of the gtp binding sites of rat 5'-adenylic acid aminohydrolase by periodate-oxidized gtp.	1. rat skeletal muscle amp deaminase (amp aminohydrolase, ec3.5.4.6) can be inactivated by incubation with the periodate-oxidized analogue of the enzyme inhibitor gtp. 2. nucleoside triphosphates and kcl at high concentrations protect against inactivation, while adp has no effect. 3. the inactivation can be reversed by the addition of gtp and amino acids and made irreversible by reduction with nabh4. this indicates that, in the binding of the oxidized gtp to the enzyme, a schiff base is formed b ...	1976	182275
rd-114, baboon, and woolly monkey viral rna's compared in size and structure.	the molecular weights, subunit compositions, and secondary structure patterns of the rnas from an endogenous baboon virus and from a woolly monkey sarcoma virus were examined and compared to the properties of the rna of rd-114, an endogenous feline virus. the high molecular weight rna extracted from each of these three viruses has a sedimentation coefficient of 52s, and a molecular length, measured by electron microscopy, of 16-20 kb (kb=kilobase, 1000 nucleotides). each such rna is a dimer, con ...	1976	182377
diagnostic tests of bovine leukemia: comparison between an hematological test and the serological diagnosis.		1976	182441
effectiveness of orally administered bordetella pertussis vaccine in mice.	oral administration of killed bordetella pertussis organisms to mice results in increased resistance to an intracerebral infection with virulent b. pertussis cells. the rate of survival is dependent on the dose of antigen. but besides specific systemic immunity, which is persistent over a long period, also transient non-specific resistance is increased. these effects are evidently induced without penetration of bacterial substances into the circulation.	1976	182602
in vitro trophic action of acth and insulin upon adrenocortical enzymes of the squaliform elasmobranch ginglymostoma cirratum (bonnaterre).		2003	182612
adrenocortical control of phenylethanolamine-n-methyl transferase and monoamine oxidase activity in the ground squirrel (citellus citellus) during the summer.		2003	182613
[protective effect of cytochrome c in carbon tetrachloride poisoning].		1976	182619
the biochemistry of sugars.	in animal cells the utilization of sugars involves one or more of the three major pathways known to occur in these cells. the glycolytic (embden-meyerhof) pathway is quantitatively the most important, and this pathway, coupled to the citric acid cycle, serves as a major source of energy. glycolysis and the citric acid cycle also provide most of the precursors for the synthesis of proteins, nucleic acids and lipids. the pentose phosphate, or hexose monophosphate oxidation, pathway is a major sour ...	2003	182650
evidences for complex formation between polymyxin b and lipopolysaccharides from serratia marcescens.	in vitro and in vivo complex formations of polymyxin b and lipopolysaccharides (lps) from resistant and sensitive cells of serratia marcescens were studied by polyacrylamide gel electrophoresis in sodium dodecyl sulfate and electron microscopy. in vitro treatment of lps from resistant cells with polymyxin b gave two populations of spherical complexes of differnt molecular weights as determined electrophoretically. similar treatment of lps from sensitive cells resulted in dissociation of the lps- ...	1976	182663
studies on the specificity of in vitro induced lymphocytotoxicity to sv40-transformed fibroblasts.	cytotoxic effector lymphocytes were induced by in vitro immunization of lymph node and spleen cells from akr-mice (h-2k) and from balb/c-mice (h-2d) to syngeneic sv40-transformed fibroblasts. the t cell-dependent cytotoxicity was specific for target cells expressing the same h2-specificity as the immunizing cells. nontransformed fibroblasts as stimulator cells did not induce efficient cytotoxicity to transformed or nontransformed target cells. incubation with phytohemagglutinin during the sensit ...	1991	182884
effect of norepinephrine and hypertonicity on k influx and cyclic amp in duck erythrocytes.	cyclic adenosine 3',5'-monophosphate (camp) accumulation and cation transport were measured in duck erythrocytes after stimulation by norepinephrine (ne) or shrinkage induced by exposure to hypertonic media (s). previously both ne and s were shown to initiate a similar transport process in this cell. ne elicited a rapid rise in cellular camp and 42k influx. both effects were eliminated by propranolol. at concentrations of ne below 3 x 10(-8) m (the concentration at which 42k influx saturates), t ...	1976	183515
[proceedings: sleep and psychotropic drugs: clinical aspects (author's transl)].		1982	183791
differential inactivation of the "l" and "ly+" amino acid transport systems by a sulfhydryl reagent and a photo-affinity probe.	using a substrate-stimulated amino acid efflux system, it has been shown that the "ly+" and "l" amino acid transport systems of mouse embryo cells in culture are differentially inhibited by parachloromercuribenzene sulfonate (pcmb-s) and the photoaffinity probe 4-fluoro-3-nitrophenylazide (fnpa). three types of evidence support the conclusion that these transport systems are mediated by separate carrier proteins. (1) the specificity of substrate-stimulated efflux is high for each system; (2) pcm ...	1976	183824
mediators of cellular immunity, their nature and assay.		1989	184210
susceptibility of "enterobacteria" to aminoglycoside antibiotics: comparisons with tetracyclines, polymyxins, chloramphenicol, and spectinomycin.	strains of enterobacteria, including common, aerobic, pathogenic gram-negative bacilli, and enterococci were tested for susceptibility to 11 aminoglycoside antibiotics by a twofold agar-dilution method with an inocula replicator. for comparison, similar tests were done with seven tetracycline analogues, two polymyxins, chloramphenicol, and spectinomycin. tobramycin compared favorably with the more active aminoglycosides, with some exceptions related to individual strains of species. the tetracyc ...	1976	184213
methionine-repressible homoserine dehydrogenase of serratia marcescens: purification and properties.	serratia marcescens sa-3 possesses two homoserine dehydrogenases and neither has any aspartokinase activity unlike the case of escherichia coli enzymes. the two enzymes have been separated. one of them is active with either nad+ or nadp+ and has been purified about 180-fold to homogeneity. this enzyme is completely repressed by the presence of 1 mm methionine or homoserine in the growth medium, but its activity is unaffected by any amino acid of the aspartate family either singly or together. in ...	1976	184374
the influence of antiepileptic drugs on some enzymes activity in the brain of mice with audiogenic epilepsy. note i. the action of phenobarbital, diphenylhydantoin and primidone.		1990	184518