Publications
| Title | Abstract | Year Filter | PMID(sorted ascending) Filter |
|---|
| trimethoprim-sulfamethoxazole for bacterial meningitis. | trimethoprim-sulfamethoxazole has excellent microbiologic activity against most pathogens that produce meningitis; both components of this drug have high penetration into tissues, including the cerebrospinal fluid. clinical experience shows that trimethoprim-sulfamethoxazole may be beneficial in the treatment of gram-negative bacillary meningitis caused by organisms only moderately susceptible to third-generation cephalosporins (enterobacter cloacae, serratia marcescens) or resistant to these an ... | 1984 | 6372565 |
| resistance types in citrobacter freundii. occurrence and resistance to ampicillin, carbenicillin, cephalothin and mecillinam. transfer of ampicillin resistance. | the resistance types of citrobacter freundii were investigated. the strains were divided into three groups according to susceptibility to penicillin derivatives. group 1, comprising the ampicillin-carbenicillin sensitive strains (a-s/ca-s), constituted 22%. group 2 (ampicillin-resistant (a-r)/ca-s) constituted 45% and group 3 (a-r/ca-r) 32%. two strains (1%) were recorded as a-s/ca-r. group 3 contained a higher proportion of multi-resistant strains than groups 1 and 2. the log2ic50 with ampicill ... | 1984 | 6375251 |
| inhibitory activity and resistance to hydrolysis by beta-lactamases of some (d,l)-7-(alpha-fluoroacylamino)cephalosporins. | the synthesis of a series of (d,l)-7-(alpha-fluoroacylamino)-cephalosporanic acids are described. in vitro antimicrobial activity was determined in comparison with the corresponding non-fluorinated compounds. none of them were found to be better than clinically used cephalosporins. resistance to and inhibition of beta-lactamases from gram-negative organisms were also determined. all the fluorinated derivatives were found to be as resistant to hydrolysis by escherichia coli r+tem beta-lactamase a ... | 1984 | 6376165 |
| novel method for studying the public health significance of macroinvertebrates occurring in potable water. | an experimental procedure was developed to study the association of selected bacteria and macroinvertebrates and their response to free available chlorine disinfection. the organisms selected for study were escherichia coli ( lacz545 ), enterobacter cloacae (atcc 23355), and the amphipod hyalella azteca . e. coli was shown to bind tightly (1.6 x 10(4) cfu per amphipod ) to this macroinvertebrate and to resist repeated attempts to wash it off. e. cloacae was shown to bind much less tightly (1.4 x ... | 1984 | 6378089 |
| use of the becton-dickinson urine culture tube with the abbott ms-2 urine screening system. | urine specimens were obtained from 312 obstetric outpatients by sterile midstream technique and aliquots placed in both becton-dickinson urine culture tubes and sterile conventional tubes. quantitative cultures were made from each tube, and each tube was screened for bacteria with the abbott ms-2 urine screening system. the time required to detect bacteriuria was recorded for both specimens. isolates from specimens containing greater than or equal to 50,000/ml gram-positive cocci or greater than ... | 1984 | 6378504 |
| mechanism of action of the new orally active cephalosporin fk027. | the mechanism of action of a new orally active cephalosporin, fk027, was compared to that of cephalexin and cefaclor to elucidate its excellent antibacterial activity against gram-negative bacteria. fk027 showed very high affinity for the penicillin-binding proteins (pbps) 3, 1a and 1bs of escherichia coli whereas cephalexin showed fairly high affinity for pbps 1a, 4 and 3. the ability of fk027 to penetrate the outer membranes of e. coli and enterobacter cloacae was less than that of cephalexin ... | 1984 | 6381449 |
| cephalosporin antibiotics as applied in surgery of bones and joints. | new cephalosporin antibiotics will continue to be discovered as old forms are found to lose effectiveness. cephalosporins currently account for a major part of any hospital pharmacy budget. they are often used inappropriately in treatment of both community and hospital infections. cephalosporins should be used when penicillins are not effective and for particular infections. a major use of cephalosporins is in prophylaxis; cephalosporin antibiotics will not prevent infections caused by organisms ... | 1984 | 6386261 |
| enzymatic profiles of enterobacter sakazakii and related species with special reference to the alpha-glucosidase reaction and reproducibility of the test system. | the enzymatic profiles of enterobacter sakazakii, enterobacter cloacae, enterobacter aerogenes, and enterobacter agglomerans were determined with the api zym system (api system s.a., la balme les grottes, france). each assay was performed three times. a simple formula was derived and applied to assess the reproducibility of the api zym tests. in addition, a separate alpha-glucosidase test was performed. all e. sakazakii isolates produced alpha-glucosidase, in contrast to the other enterobacter i ... | 1984 | 6386874 |
| an evaluation of the bacteriolytic and biochemical properties of ceftiolene (42980rp). | ceftiolene (42980rp) is a new cephalosporin with a broad antibacterial spectrum similar to cefotaxime or ceftriaxone. the characteristics of ceftiolene have been tested in a variety of assays involving various biochemical aspects of the mode of action of beta-lactam antibiotics. the affinities of ceftiolene for penicillin-binding proteins were very comparable with those of ceftriaxone and cefotaxime for escherichia coli, and generally greater than those of latamoxef (moxalactam) for the higher m ... | 1984 | 6394571 |
| reproducibility of the ms-2 system for identification of members of the family enterobacteriaceae: a collaborative study with blindly assigned reference stains. | the reproducibility of identification and biochemical reactions for five different reference organisms of enterobacteriaceae; proteus vulgaris, klebsiella pneumoniae, escherichia coli, serratia marcescens, and enterobacter cloacae, were evaluated using the updated ms-2 system software (abbott laboratories, diagnostic division, irving, tex.) in a collaborative study involving 11 laboratories. when a total of 220 randomly coded test organisms were blindly examined, the ms-2 system correctly identi ... | 1984 | 6394615 |
| direct identification and susceptibility testing of gram-negative bacilli from bactec bottles by use of the ms-2 system with updated bacterial identification software. | the abbott ms-2 system (abbott laboratories, diagnostic division, irving, tex.), equipped with updated bacterial identification software (version 03.02), was used to perform both direct identification and susceptibility tests on gram-negative bacilli from positive bactec blood culture bottles. ninety-eight of 101 enterobacteriaceae strains, one strain of acinetobacter calcoaceticus, and two strains of pseudomonas aeruginosa were correctly identified by following a direct inoculation procedure. o ... | 1984 | 6394624 |
| cloning and expression in escherichia coli k-12 of the structural gene for outer membrane phoe protein from enterobacter cloacae. | in escherichia coli k-12, the phoe gene encodes an outer membrane pore protein, which is induced by phosphate starvation. the corresponding gene of enterobacter cloacae was transferred to e. coli k-12 by using rp4::mini mu plasmid pulb113 and selecting for r-prime plasmids that carry the genes proa and prob, which are closely linked to phoe in e. coli k-12. the phoe gene was subcloned into the multicopy vector pacyc184, and the location of the gene was determined by analysis of in vitro construc ... | 1984 | 6397399 |
| characterization of beta-lactamase induction in enterobacter cloacae. | the induction of beta-lactamase was studied in a strain of enterobacter cloacae. a wide variety of beta-lactam compounds were found to induce beta-lactamase in this organism, and the degree of induction was directly related to the stability of the inducer to degradation by the enzyme. the kinetics of the induction process were consistent with a system normally under repressor control, suggesting a direct interaction of the beta-lactam compound with a repressor protein in the e. cloacae cells. al ... | 1983 | 6402977 |
| polymicrobial bacteremia associated with lipid emulsion in a neonatal intensive care unit. | polymicrobial bacteremia developed in 5 of 20 infants in a neonatal intensive care unit during a 48-hour period; 2 infants died. klebsiella pneumoniae serotypes 21 and 24 and enterobacter cloacae were isolated from four infants, and k. pneumoniae serotype 24 and e. cloacae were isolated from the other infant. case-control studies revealed an association between receipt of lipid emulsion on one day and the subsequent development of bacteremia (p = 0.0005). epidemiologic evidence suggested that ex ... | 1983 | 6408618 |
| selection of variants of gram-negative bacteria with elevated production of type 1 beta-lactamase. | variants of pseudomonas aeruginosa, citrobacter freundii and enterobacter cloacae were isolated that produced elevated levels of type 1 beta-lactamase. the variants were readily isolated on antibiotic-containing agar and showed resistance to a wide range of beta-lactam antibiotics including some regarded as being relatively stable to the beta-lactamase produced. | 1983 | 6411674 |
| cefamandole therapy in hand infections. | hand lacerations, especially when inadequately treated, may result in infections caused by aerobic or anaerobic bacteria. anaerobic infections most commonly result from human bite injuries in which there is contact between hand and mouth. the search continues for an ideal antibiotic to employ when anaerobic organisms are suspected. in this study cefamandole, a new cephalosporin antibiotic, was employed whenever anaerobic hand infections were suspected following trauma. in each patient quantitati ... | 1983 | 6415153 |
| [characteristics of the substrate specificity of the crude endogenous beta-lactamases of gram-negative bacteria]. | fifty clinical strains of gram-negative bacteria highly resistant to beta-lactam antibiotics were studied and 9 strains producing beta-lactamases were selected. from these cultures crude beta-lactamases were isolated. the substrate specificity of these crude preparations and their sensitivity to the inhibitory effect of dicloxacillin, methicillin and carbenicillin were studied with the spectrophotometric and hydroxylamine methods. the results of the study obtained with the 2 methods were in the ... | 1983 | 6416154 |
| enteral nutrient solutions. limiting bacterial growth. | bacterial contamination of enteral nutrient solutions ( ens ) in ffcess of food product standards is known to occur in the hospital setting. the large amounts of bacteria often given with ens have been shown to create a reservoir for nosocomial infections, and nonpathogenic bacteria have been implicated. patient tolerance is dependent on immune status and the bacterial load delivered to the gut. the purpose of this study was to evaluate the bacterial growth-sustaining properties of various ens a ... | 1984 | 6428286 |
| effects of time, temperature, and preservative on bacterial growth in enteral nutrient solutions. | bacterial contamination and the effects of time, temperature, and preservative on bacterial growth in enteral nutrient solutions were studied. bacteria were counted after 24-hour incubation of five samples of frozen travasorb std (travenol laboratories) from the pharmacy and five samples freshly reconstituted in the dietary department. growth in samples of travasorb std prepared in the pharmacy was studied after (1) fresh mixing, 24-hour refrigeration, and 12 hours at room temperature, (2) freez ... | 1984 | 6430069 |
| [isolation of propionibacterium acnes and enterobacter cloacae from a case of infective endocarditis]. | 1984 | 6431026 | |
| effect of ph, application technique, and chlorine-to-nitrogen ratio on disinfectant activity of inorganic chloramines with pure culture bacteria. | the influence of ph, application technique, and chlorine-to-nitrogen weight ratio on the bactericidal activity of inorganic chloramine compounds was determined with stock and environmental strains of escherichia coli, salmonella spp., pseudomonas aeruginosa, klebsiella pneumoniae, and enterobacter cloacae. the rate of inactivation increased from 1.5 to 2 times as the chlorine-to-nitrogen weight ratio was adjusted from 2:1 to 5:1, 5 to 6 times as the ph was decreased from 8 to 6, and 5 to 6 times ... | 1984 | 6437328 |
| [bacteriocin typing for clinical isolates of enterobacter cloacae--an epidemiologic consideration]. | 1984 | 6439786 | |
| temocillin: in vitro activity against 734 selected clinical isolates, including beta-lactamase-producing strains. | the in vitro activity of temocillin against 734 clinical isolates was tested by broth microdilution. good activity was demonstrated against enterobacteriaceae and both beta-lactamase-positive and -negative strains of haemophilus influenzae and neisseria gonorrhoeae. there was little to no activity against gram-positive cocci and nonfermenting gram-negative bacilli. bactericidal activity and effect of inoculum size on temocillin activity were comparable to that of ticarcillin. temocillin was stab ... | 1984 | 6443203 |
| [bacteriological investigations with a new semisynthetic oxy-beta-lactam antibiotic ly 127935 (author's transl)]. | the antimicrobial activity of a new oxy-beta-lactam antibiotic ly 127935 against 1066 strains of gram-negative and gram-positive bacterial was evaluated in comparison to cephalothin. the antibiotic has a very wide spectrum and is exceptionally active, in particular against gram-negative rods. it is also active against multiresistant problem strains found in intensive care units (enterobacter cloacae, serratia marcescens, indole-positive proteus), and proved to be quite effective against pseudomo ... | 1980 | 6445339 |
| [fosfomycin, a new antibiotic: in vitro activity compared with mezlocillin, cefuroxime and gentamicin]. | in vitro investigations with fosfomycin, mezlocillin, cefuroxime, and gentamicin against staphylococci, enterobacteriaceae an pseudomonadaceae were carried out by agar dilution method on mueller-hinton agar. the fosfomycin breakpoint for the low dosage of 2-3 times 3 g per infusion daily was defined with 16 micro g/ml and for the high dosage of 2-3 times 5 g fosfomycin per infusion with 64 micro g/ml. at a concentration of 16 micro g/l fosfomycin more than 90% of the cultures of staph. aureus (p ... | 1980 | 6453080 |
| successful treatment of gram-negative bacillary meningitis with moxalactam. | meningitis caused by enteric gram-negative bacilli is relatively uncommon but is very difficult to treat despite susceptibility in vitro to many antimicrobics. a major problem appears to be poor entry of many drugs into the central nervous system. moxalactam is an investigational cephalosporin that attains concentrations in the cerebrospinal fluid that are 15% to 30% of contemporaneous serum concentrations; moreover, it is quite active against many of the enteric gram-negative bacilli. we used m ... | 1981 | 6455950 |
| [clinical evaluation of 6059-s therapy in children (author's transl)]. | a new semisynthetic 1-oxa-beta-lactam derivative, 6059-s, was evaluated for its safety and efficacy in children. twenty-five patients were treated with 10 to 274 mg/kg per day of 6059-s by intravenous administrations. the diagnosis of the patients were acute pharyngitis (2), acute bronchitis (2), pneumonia (4), pertussis (4), acute enterocolitis (2), recurrent urinary tract infection (2), suspected septicemia (3), and acute purulent meningitis (1); and the remaining 5 patients were considered to ... | 1981 | 6457168 |
| [laboratory and clinical studies of 6059-s in pediatric field (author's transl)]. | the authors have carried out the laboratory and clinical studies of 6059-s. the results were as follows: the sensitivity was estimated by the plate dilution method on 27 strains of s. aureus, 26 strains of e. coli, k. pneumoniae and p. aeruginosa, 21 strains of salmonella sp. and 9 strains of gm resistant p. aeruginosa isolated from patients. the distribution of sensitivity of s. aureus was 6.25-12.5 micrograms/ml and the peak of distribution was 6.25 micrograms/ml. the growth of 80.8% of e. col ... | 1981 | 6457177 |
| siderophore production by enterobacter cloacae and a common receptor protein for the uptake of aerobactin and cloacin df13. | iron-starved cultures of enterobacter cloacae produced two siderophores, identified as enterochelin and aerobactin. the aerobactin was excreted in larger amounts than was enterochelin, and it was synthesized preferentially in the late logarithmic and stationary growth phases under iron-deficient conditions. enterochelin was synthesized by cultures in the logarithmic phase of growth and preferentially in medium with 1 microm ferric chloride. both siderophores appeared to be excreted immediately a ... | 1982 | 6461633 |
| obturator foramen grafts: the preferable alternate route? | although the femoral canal is the standard entrance route for vascular grafts to the lower extremity, several situations may arise that preclude the use of this route. in these circumstances an alternate pathway for revascularization is required. experience in our center with the use of obturator foramen grafts for revascularization of nine limbs in eight patients is reported and underscores the value of this pathway as an alternative route for limb revascularization. the obturator foramen was e ... | 1982 | 6462077 |
| [dibekacin in the treatment of urinary infections in the elderly]. | urinary tract infections in the elderly are severe and intractable, often justifying the use of aminoglycosides. we studied the effects of dibekacin in 28 patients, with no vesical catheter, whose average age was 78 +/- 6.1 years. the drug was given for ten days, in an average dose of 2.1 mg/kg/day divided into two injections. serum concentration was measured after one hour on day 1 and after eight hours on days 1 and 10. causative pathogens, all susceptible to dibekacin, were: 18 e. coli, 3 pro ... | 1984 | 6462747 |
| effect of antibiotic use on the incidence of cephalosporin resistance in two australian hospitals. | the incidence of resistance of gram-negative bacteria to three generations of cephalosporins was surveyed in two large hospitals with widely differing rates of cephalosporin usage. overall resistance (mic greater than 5 mg/l) of enterobacteriaceae to cefotaxime in the hospital using large amounts of cephalosporins was 4% compared with 0.7% in the other. enterobacter species accounted for most resistant isolates and resistant enterobacter cloacae replaced sensitive strains in four patients given ... | 1984 | 6501136 |
| in vitro activity of win 49375 compared with those of other antibiotics in isolates from cancer patients. | the activity of win 49375 [6-fluoro-1, 4-dihydro-1-(methylamino)-7-(4-methyl-1-piperazinyl)-4-oxo-3- quinolinecarboxylic acid], a new synthetic quinolone, was tested in vitro against 587 clinical isolates. the mics for 90% of isolates of escherichia coli, klebsiella pneumoniae, and enterobacter cloacae were 0.20, 1.56, and 0.39 microgram/ml, respectively. the mics for 90% of isolates of pseudomonas aeruginosa and serratia marcescens were both 3.12 micrograms/ml. win 49375 was minimally active ag ... | 1984 | 6508271 |
| composition of o-antigenic lipopolysaccharides from enterobacter cloacae. | analyses have been carried out on lipopolysaccharides (lps) from 14 strains of enterobacter cloacae representing different o serotypes. all of the products appeared to have a composition and architecture typical of enterobacterial lps, but points of interest include the absence of phosphate residues from the core oligosaccharide, the presence of both l-glycero-d-mannoheptose and d-glycero-d-mannoheptose (ratio usually about 4:1), and the presence in lipid a of small amounts of fatty acids with o ... | 1984 | 6521668 |
| enterobacter sakazakii: a tween 80 esterase-positive representative of the genus enterobacter isolated from powdered milk specimens. | enterobacter sakazakii is the new species name introduced in 1977 for yellow-pigmented strains originally designated as yellow enterobacter cloacae. all of the six e.sakazakii strains isolated from powdered milk specimens were found to produce tween 80 esterase after 7 days of incubation at 25 degrees c and 37 degrees c. from e.cloacae it is distinguishable by reactions in four, or even three, biochemical tests, i.e. by production of yellow pigment, positive production of tween 80 esterase and b ... | 1984 | 6527001 |
| an outbreak of gentamicin-resistant enterobacter cloacae infections in a pediatric intensive care unit. | the intensive care unit at children's medical center in dallas is a medical-surgical unit that cares for pediatric patients of all ages. in 1978 an outbreak of infections occurred that was caused by a gentamicin-resistant strain of enterobacter cloacae. thirty of the 34 patients involved in the outbreak were neonates. six patients developed bacteremia, five of them neonates. the neonates who became infected were significantly smaller (less 1500 g) and more premature (less than 35 weeks) than con ... | 1983 | 6553023 |
| infant feeding formula contaminated by enterobacter cloacae. | 1984 | 6561177 | |
| enterobacter cloacae-contaminated cardioplegic solution. discovery and eradication of a pharmacy reservoir. | 1984 | 6566522 | |
| enterobacter sepsis in infants and children due to contaminated intravenous fluids. | sixty-three cases of nosocomial sepsis occurring from april through october 1981, in a 500-bed pediatric hospital, were traced to bacterial contamination of intravenous fluid produced by a single manufacturer. two species of uncommon blood stream pathogens, enterobacter cloacae and enterobacter agglomerans contaminated the fluid. infections with these organisms might have contributed to the death of four patients; two who were immunosuppressed, one who was asplenic and one premature infant. epid ... | 1984 | 6567611 |
| in-vitro activity of cefotetan and other cephalosporins against multiresistant strains of enterobacteriaceae. | the activity of cefotetan against multiresistant strains of escherichia coli and klebsiella aerogenes was comparable with that of cefotaxime and ceftazidime, the mean mics being 0.11 and 0.06 mg/l, respectively. multiresistant strains of enterobacter cloacae showed a high level of resistance to cefotetan in common with other cephalosporins such as cefuroxime, cefamandole and cefoxitin, but were sensitive to ceftazidime and cefotaxime. | 1983 | 6573310 |
| direct dilution sampling, quantitation, and microbial assessment of open-system ventilation circuits in intensive care units. | in a systematic approach, 37 duplicate samples of open system circuits (bennett ma-1 ventilators) of patients in medical and surgical intensive care units were processed by direct and serial (apha guidelines) dilutions. the paired difference test on 15 of the in-use circuitry solution samples indicated no difference between the direct and serial dilution methods (p less than 0.001). seventy-seven additional respiratory therapy circuitry samples from similar intensive care patients were analyzed ... | 1983 | 6575015 |
| in vitro combination effects of cefotetan with four aminoglycosides, piperacillin and mezlocillin on gram-positive and gram-negative nosocomial bacteria. | the in vitro efficacy of cefotetan in combination with gentamicin, tobramycin, amikacin, netilmicin against staphylococcus aureus, staphylococcus epidermidis and enterobacter cloacae and with piperacillin and mezlocillin against escherichia coli, klebsiella pneumoniae, serratia marcescens and enterobacter cloacae was compared by use of the checkerboard agar dilution technique. on average, 60% of the gram-negative and 46% of the gram-positive strains were inhibited by additive, but only 22% of th ... | 1984 | 6596165 |
| in vitro antibacterial activity of sm-1652, a new broad-spectrum cephalosporin with antipseudomonal activity. | sm-1652 (sodium 7-[d(-)-alpha-(4-hydroxy-6-methylpyridine-3-carboxamido)-alpha-(4-hydroxyphenyl)acetamido]-3-[(1-methyl-1h-tetrazol-5-yl) thiomethyl]-3-cephem-4-carboxylate) is a new semisynthetic cephalosporin derivative with a broad spectrum of antibacterial activity. its in vitro activity against gram-positive bacteria was comparable to that of cefazolin. sm-1652 exceeded cefazolin in potency and broadness of antibacterial activity against such enterobacteriaceae as indole-positive proteus sp ... | 1983 | 6601470 |
| cefotetan: profile of in-vitro activity. | cefotetan, a novel 7 alpha-methoxy cephalosporin, was shown to be comparable to other third-generation cephalosporins when tested in vitro against 1063 gram-negative clinical isolates of 11 species. ninety per cent of all isolates of escherichia coli, klebsiella, proteus mirabilis, proteus vulgaris, proteus rettgeri, providencia stuartii, serratia marcescens and citrobacter freundii were inhibited by concentrations of cefotetan between 0.07 and 3.2 mg/l. activity against gram-positive cocci was ... | 1983 | 6601656 |
| synthesis and beta-lactamase inhibitory activities of some clavulanic acid analogues. | clavulanic acid analogs lacking the c-3 carboxyl group are potent inhibitors of both plasmid and chromosomally mediated beta-lactamases. they exhibit only low intrinsic anti-bacterial activity, but potentiate the activity of ampicillin and cephaloridine against beta-lactamase producing escherichia coli and enterobacter cloacae in vitro. no synergism was observed in beta-lactamase negative strains. the e. coli tem 1 and the e. cloacae p99 enzymes are inhibited in a progressive and irreversible ma ... | 1983 | 6602120 |
| antibacterial activity of cefoperazone alone and in combination against cephalosporinase-producing enterobacter cloacae. | the activity of cefoperazone against a strain with an inducible cephalosporinase and a mutant that produces the enzyme constitutively indicates that the low inducer activity of this antibiotic plays an important role in its activity against enterobacter cloacae. | 1983 | 6605112 |
| hr 810, a cephalosporin with low affinity for enterobacter cloacae beta-lactamase. | 1983 | 6605247 | |
| nonspecific induction of beta-lactamase in enterobacter cloacae. | since the introduction of the new beta-lactamase-stable beta-lactam compounds, inducible beta-lactamases have become increasingly important clinically [1]. it has recently been pointed out that most beta-lactam antibiotics appear to be affected by these derepressed enzymes either by hydrolysis or by the nonhydrolytic barrier mechanism [2]. until now, it has generally been assumed that beta-lactamases are induced only by the beta-lactam compounds themselves. we investigated an e cloacae strain th ... | 1983 | 6605393 |
| in vitro antibacterial activity and beta-lactamase stability of e-0702, a new cephalosporin. | the in vitro activity of e-0702 was compared with the in vitro activity of cefotaxime, ceftazidime, moxalactam, and aztreonam against 600 gram-positive and gram-negative aerobic and anaerobic isolates. e-0702 had a minimal inhibitory concentration for 50% of isolates (mic50) of 25 micrograms for staphylococcus aureus, 50 micrograms for staphylococcus epidermidis, and 1.6 to 3.1 micrograms for streptococci, with streptococcus faecalis resistant. e-0702 had mic50s against escherichia coli, klebsie ... | 1983 | 6605718 |
| differentiation of resistance determinants to cefamandole and cefoxitin in enterobacter cloacae strains. | the mechanism of resistance to cefamandole and cefoxitin was investigated in enterobacter cloacae with the aid of cefamandole-resistant variants and their derived beta-lactamase-deficient mutants. cefamandole-resistant variants were easily obtained from clinical isolates by direct selection. massive beta-lactamase production seemed to be the underlying resistance mechanism, although lack of penetrability may further substantiate this resistance. the mechanism of resistance to cefoxitin in parent ... | 1983 | 6606106 |
| crystallographic data for the beta-lactamase from enterobacter cloacae p99. | the beta-lactamase from enterobacter cloacae p99 has been crystallized from polyethylene glycol solution at ph 7. x-ray examination of the orthorhombic crystals shows the space group is p2(1)2(1)2 with unit cell dimensions a = 77.4 a, b = 69.4 a, and c = 63.6 a. there is one molecule of molecular weight 39,000 in the asymmetric unit. | 1983 | 6606712 |
| detection of pse-2 beta-lactamase in enterobacteria. | pse-2, a plasmid-mediated beta-lactamase which was previously considered pseudomonas specific, was observed in clinical isolates of escherichia coli, klebsiella pneumoniae, providencia stuartii, and enterobacter cloacae. all four isolates transferred pse-2 production, together with resistance to gentamicin, tobramycin, kanamycin, and sulfamethoxazole, into escherichia coli j62-1 and pseudomonas aeruginosa pu21. transfer correlated with acquisition by the transconjugants of a 65-megadalton plasmi ... | 1984 | 6608920 |
| [in vitro antibacterial activity of cefoperazone]. | the in vitro antibacterial activities of cefoperazone (cpz) against clinical isolates including various beta-lactamase-producing strains were studied and compared with those of cefotiam (ctm). cpz had a broad spectrum against gram-negative and gram-positive bacteria. especially, cpz showed apparently more potent antibacterial activities than ctm against enterobacter cloacae, serratia marcescens, and pseudomonas aeruginosa. however, cpz was less active than ctm against staphylococcus aureus and p ... | 1983 | 6609251 |
| development of resistance to cephalosporins in clinical strains of citrobacter spp. | the predominant beta-lactam antibiogram of citrobacter freundii resembles that of enterobacter cloacae in demonstrating resistance to cephalothin and cefoxitin with susceptibility to the newer cephalosporins. four representative strains of c. freundii were reversibly induced to high-level beta-lactamase production by cefoxitin, and mutants with stable, high-level production were selected with cefamandole. the mutants were resistant to several second- and third-generation cephalosporins. comparis ... | 1984 | 6610388 |
| superinfections in herpes simplex keratitis. | we reviewed 15 cases of culture-proven corneal superinfections in 15 patients (eight men and seven women ranging in age from 41 to 86 years) with recurrent herpes simplex keratitis. the factors that appeared to increase the risk of superinfection were the presence of an epithelial defect (found in all 15 cases), a history of recurrent herpetic keratouveitis (found in ten cases), and the use of topical corticosteroids (found in 13 cases). eight of the 15 patients were taking antibiotics at the ti ... | 1983 | 6614114 |
| effects of selected hydrazines on the early death rates of enterobacter cloacae. | 1983 | 6626761 | |
| two new monobactam antibiotics produced by a flexibacter sp. i. taxonomy, fermentation, isolation and biological properties. | two new beta-lactam antibiotics, namely sq 28,502 and sq 28,503, have been isolated from fermentations of a flexibacter sp. they are demethoxy monobactams with oligopeptide side chains and have molecular weights of 1,462 and 1,446, respectively. these beta-lactams show a high degree of stability to a variety of beta-lactamases and act as potent irreversible inactivators of p99 beta-lactamase from enterobacter cloacae. they exhibit weak antibacterial activity. | 1983 | 6643274 |
| o serotyping scheme for enterobacter cloacae. | a serotyping scheme for enterobacter cloacae based on heat-stable somatic antigens is described. a total of 28 antisera were prepared in rabbits, and titers of agglutinins were high (greater than 640). some cross-reactions were observed, and 11 sera required absorption before routine use. of 300 clinical isolates from 66 hospitals, 77.6% were typable, 11.4% were not agglutinated by any of the sera, and 11.0% were autoagglutinable in saline. the eight most frequent serotypes were o3 (21.3%), o8 ( ... | 1983 | 6643660 |
| serratia ficaria isolated from a leg ulcer. | serratia ficaria was isolated from culture of a leg ulcer of a 44-year-old woman who had venous insufficiency and alcoholic cirrhosis. although pseudomonas maltophilia, p acidovorans, and enterobacter cloacae were also present, s ficaria was isolated in large numbers and was considered to contribute significantly to this infection. this represents the third known clinical isolation of this bacterium. | 1983 | 6648629 |
| [taxonomic study of free nitrogen-fixing bacteria isolated from the endorhizosphere of rice]. | twenty strains of free-living n2-fixing bacteria, isolated from the endorhizosphere of rice in rice soils of senegal, were studied on the basis of 259 morphological, physiological, biochemical and nutritional characters. half of them were gram-negative small rods with polar flagella and showing a strictly respiratory metabolism; they were characteristic of the genus pseudomonas. a first group of 6 strains was related to the p. cepacia-p. marginata group characterized by lophotrichous flagella; t ... | 1983 | 6651126 |
| combined defibrinated human blood and antimicrobial drug activities against enterobacter cloacae. | the combinations of 11 antimicrobial drugs and fresh human defibrinated blood were examined for potential additive effects against several isolates of enterobacter cloacae recovered from patients with bacteremia or meningitis. aminoglycosides (amikacin, gentamicin, netilmicin) proved most efficacious, followed by cephalosporins (lamoxactam, cefotaxime, ceftizoxime) and ureidopenicillins (mezlocillin, piperacillin). nalidixic acid, nitrofurantoin, and cotrimoxazole yielded indifferent effects. th ... | 1983 | 6653172 |
| salmonella and other enterobacteriaceae found in commercial poultry feed. | poultry feed (mash and pelleted) and meat and bone meal samples were collected from commercial mills. all samples were analyzed for enterobacteriaceae count (ent) and salmonella. the genus and species of the various enterobacteriaceae present were also determined. the average ent for mash, pelleted, and meal samples was log 4.1, .8, and 1.8/g, respectively. enterobacteriaceae were present in 100, 60, and 92% and salmonella in 58, 0, and 92% of the mash, pelleted, and meal samples, respectively. ... | 1983 | 6657560 |
| infection in artificial blood pump implantation. | infection has been observed in artificial heart experimentation to be of early onset and generally within the first 2 postoperative weeks. the organisms most often detected in blood cultures were pseudomonas aeruginosa, enterobacter cloacae, e. coli and enterococcus, all of which are intestinal species. contamination is thus thought to be the most plausible cause of perioperative infection. absolute sterility must be maintained in animal care areas and blood access to these animals is to be mini ... | 1983 | 6673282 |
| antibacterial activity of aztreonam: a synthetic monobactam. a comparative study with thirteen other antibiotics. | the in vitro activity of aztreoman (sq 26, 776), a new monocyclic beta-lactam antimicrobial agent, was determined against 1720 bacteria, all clinical isolates, and compared with that of thirteen beta-lactam and aminoglycoside antibiotics. aztreonam inhibited 90% of citrobacter diversus, citrobacter freundii, enterobacter agglomerans, e. coli, klebsiella pneumoniae, proteus mirabilis, proteus morganii, proteus rettgeri, proteus vulgaris and salmonella sp. by less than or equal to 0.4 micrograms m ... | 1983 | 6684718 |
| [change in the vaginal smear cycle following conventionalization and monocontamination of germ-free rats with enterobacter cloacae]. | the relationship between the microbial organism infection and the vaginal smear cycle was investigated using 12 germfree wistar imamichi rats at 50 days of age. germfree rats exhibited continuous vaginal cornification which occasionally interrupted by the appearance of nucleated epithelial cells. however, leukocytes which are characteristic of the metestrus and diestrus stage in conventional rats were not observed in the vaginal smear of these animals. at 70 days of age, 8 animals were taken out ... | 1983 | 6686559 |
| chemiluminescent response to pathogenic organisms: normal human polymorphonuclear leukocytes. | chemiluminescence (cl) is a sensitive indicator of phagocytosis and intracellular killing; however, little is known of the normal cl response by human polymorphonuclear leukocytes to different pathogenic microorganisms. we investigated the luminol-enhanced cl response of normal polymorphonuclear leukocytes to a number of common bacterial pathogens and two yeasts. we analyzed the cl response to viable and heat-killed microorganisms at 25 and 37 degrees c. the cl response to all microorganisms was ... | 1984 | 6693174 |
| bacterial interference with coliform colony sheen production on membrane filters. | the membrane filter (mf) method for detection and enumeration of coliform bacteria in drinking water requires that the coliforms both grow and produce a green metallic sheen when the filter is incubated on modified endo medium at 35 degrees c for 22 h. large numbers of noncoliform bacteria, which are enumerated by the standard plate count (spc) technique, can interfere with the detection of coliforms on mf. this paper presents quantitative evidence from laboratory experiments on the interference ... | 1984 | 6696423 |
| canaliculitis caused by enterobacter cloacae: report of a case. | a 65-year-old man developed canaliculitis first of the left lower and later of the left upper lacrimal canaliculus. mucoid material expressed from the upper canaliculus grew a pure culture of enterobacter cloacae, the colonies of which had a stringy, tenacious, mucoid property consistent with the clinical findings. treatment with topical chloramphenicol and oral ampicillin was followed by complete resolution. | 1984 | 6712916 |
| [epidemiological study of a multiresistant enterobacter cloacae causing iatrogenic infection in a surgical unit]. | 1984 | 6720166 | |
| treatment of invasive enterobacter cloacae burn wound sepsis with topical nitrofurazone. | nine patients with invasive enterobacter cloacae burn wound sepsis were identified in a series of 400 admissions to our burn center. in vitro antibacterial testing of topical agents revealed sensitivity to nitrofurazone cream. treatment of this series of patients with nitrofurazone resulted in an overall 66% survival compared with an 86% mortality reported in the literature. we recommend that topical antibacterial sensitivity testing be routinely performed in the microbiology laboratory for isol ... | 1984 | 6737529 |
| [enterobacter cloacae. in vivo emergence of a variant resistant to new beta-lactams during treatment with lamoxactam-gentamicin]. | in a patient recently operated for an abdominal gun wound, and given gentamicin-cephalosporin (cefoxitin for one day, then moxalactam) for 11 days, treatment failed as a result of emergence of a e. cloacae variant resistant to beta-lactams only, i.e. carbenicillin, mezlocillin, cefamandole (cfm), cefoperazone (cpz), cefotaxim (ctx) and moxalactam ( mox ). the initial susceptible strains isolated from blood cultures (sh1, sh2) and the resistant ones isolated 11 days later from pancreatic pus (rp) ... | 1984 | 6739148 |
| a transport-dependent energy burden imposed by growth of enterobacter cloacae in the presence of 10% sodium dodecyl sulfate. | growth of enterobacter cloacae in a glucose asparagine salts medium in the presence of 10% sodium dodecyl sulfate entailed an energy burden in the form of a 20% decreased cell yield, a 30% faster rate of glucose utilization, and a 70% increased rate of oxygen consumption. similar detergent-induced decreases in cell yield were observed with 10 other sugars and sugar alcohols. only glycerol supported equivalent cell growth in the presence and absence of sodium dodecyl sulfate. a model is presented ... | 1984 | 6744127 |
| typing of enterobacter spp. by bacteriocin susceptibility and its use in epidemiological analysis. | most clinical isolates of enterobacter cloacae are bacteriocinogenic and susceptible to bacteriocins. both rapidly diffusing, nonsedimentable, protease-susceptible and slowly diffusing, sedimentable, protease-resistant bacteriocins are produced. a practicable system was devised for epidemiological typing of e. cloacae isolates by their patterns of susceptibility to bacteriocins. a set of eight bacteriocin-producing strains was grown on tryptic soy agar plates for 16 h. after removal of the produ ... | 1984 | 6746888 |
| [gram negative bacilli endocarditis ]. | gram negative bacilli endocarditis are unfrequent. nevertheless we encountered 28 cases of them (8.8%) among 320 endocarditis of which 10 were primitive and 7 cases (10.9%) among 65 prosthetic endocarditis. bacterial species were 12 pseudomonas aeruginosa, 2 ps, stutzeri, 1 ps. maltophilia, 2 klebsiella pneumoniae, 2 escherichia coli, 3 serratia marcescans, 1 enterobacter cloacae, 1 brucella, 1 hemophilus aphrophilus, 1 fusobacterium funduliformis, 18 cases were hospital acquired infections rela ... | 1982 | 6750526 |
| population analysis of sensitivity to ampicillin and carbenicillin in eschericia coli and enterobacter cloacae. | population analysis of sensitivity to ampicillin (a) and carbenicillin (ca) was carried out with four strains of e. coli and five strains of enterobacter cloacae. the two a-sensitive/ca-sensitive (a-s/ca-s) e. coli strains were homogeneous as regards a-sensitivity. from the a-resistant/ca-s (a-r/ca-s) e. coli strains, it was possible to select a-r/ca-r mutants. mutation frequency approx. 10-7.5. when the inoculum of a-s/ca-s e. coli was raised, it was possible to select a-r/ca-s/cephalothin-r va ... | 1982 | 6751021 |
| insect immunity: isolation and structure of cecropins b and d from pupae of the chinese oak silk moth, antheraea pernyi. | the immune system in the chinese oak silk moth, antheraea pernyi, has been compared with that of the cecropia moth which has been characterized earlier. antibacterial activity against escherichia coli was induced in diapausing pupae by injection of viable e. coli or enterobacter cloacae. the activity reached a maximum on day 7-8 after which the response gradually declined. the pupae produced a set of immune proteins with p4 and p5 as major labelled components similar to that earlier found in cec ... | 1982 | 6754375 |
| [outbreak of hospital infection, due to members of the klebsielleae tribe, in an intensive care unit for infants]. | at the pediatric intensive care unit of the provincial regional hospital, in río cuarto, argentina, nearly all hospitalized infants showed clinical symptoms of septicaemia and gastroenteritis. neither salmonella nor shigella were found in the stool cultures, but klebsiella pneumoniae was isolated as predominant flora. three haemocultures displayed k. pneumoniae and enterobacter cloacae; the other three developed only e. cloacae. since the infants came from different places and it was possible to ... | 1980 | 6755552 |
| outer membrane permeation of beta-lactam antibiotics in escherichia coli, proteus mirabilis, and enterobacter cloacae. | mutant strains lacking outer membrane protein(s) were isolated from escherichia coli, proteus mirabilis, and enterobacter cloacae. the outer membrane protein(s) of p. mirabilis and e. cloacae corresponding to e. coli porin were identified on the basis of their function, namely, their ability to allow the permeation of glucose as demonstrated by [14c]glucose uptake by intact cells. p. mirabilis has only one outer membrane pore protein (molecular weight, 40,000), but e. cloacae has at least two su ... | 1982 | 6758687 |
| antimicrobial activity of heparin. | single clinical isolates of eight species of microorganisms were incubated in solutions of heparin and brain heart infusion broth at various concentrations to determine the possible antibacterial effect of heparin. at heparin concentrations ranging from 12.5 to 400 u/ml, the effect on escherichia coli, pseudomonas aeruginosa, candida albicans, staphylococcus aureus, and s. epidermidis varied with brain heart infusion broth concentrations of 1.2 to 10% and inocula of 10(2) to 10(6) colony-forming ... | 1980 | 6766462 |
| in vitro antibacterial activity and susceptibility of cefsulodin, an antipseudomonal cephalosporin, to beta-lactamases. | cefsulodin sodium (sce-129, cgp-7174/e), active in minimum inhibitory concentrations (mics) of 0.5 to 64 microgram/ml, was about 16- to 32-fold more active than carbenicillin against psuedomonas aeruginosa. it was also active against p. diminuta, p. maltophilia, p. paucimobilis, and p. pseudoalcaligenes (mics of 1 to 32 microgram/ml) but not against other species of pseudomonas or other gram-negative bacteria. except with highly carbenicillin-resistant isolates, mics of cefsulodin for p. aerugin ... | 1980 | 6770753 |
| enteral feeds contaminated with enterobacter cloacae as a cause of septicaemia. | 1981 | 6781681 | |
| the calcifying epithelial odontogenic tumor: a case report. | a case report of a rather rare neoplasm, the calcifying epithelial odontogenic tumor, is added to the literature. an aggressiveness not normally associated with this tumor is described. the treatment, involving the segmental resection of the left mandible and immediate reconstruction, is reported. a complication with the infective organism enterobacter cloacae and the subsequent necessity to regraft the area is noted. long-term inter-maxillary fixation resulted in adequate occlusion and only sli ... | 1981 | 6807905 |
| trapping of nonhydrolyzable cephalosporins by cephalosporinases in enterobacter cloacae and pseudomonas aeruginosa as a possible resistance mechanism. | resistance to cefotaxime (cta) and ceftriaxone (ctr) in enterobacter cloacae and pseudomonas aeruginosa was investigated in several strains which are susceptible or resistant to these agents. all strains produced a chromosomally mediated cephalosporinase of the richmond type 1. beta-lactamases in susceptible strains were inducible, whereas resistant strains produced the enzymes constitutively. cta and ctr were very poor substrates but potent inhibitors of all enzymes. binding to, rather than hyd ... | 1982 | 6808912 |
| [n-formimidoyl-thienamycin: in vitro activity in bacteria with resistance to beta-lactam antibiotics or gentamicin]. | the minimum inhibitory concentration (mic) and the minimum bactericidal concentration (mbc) of n-formimidoyl-thienamycin were determined for 25 strains each of escherichia coli, klebsiella pneumoniae, enterobacter cloacae, serratia marcescens and pseudomonas aeruginosa which were resistant to gentamicin and/or acylureido penicillins or cefotaxime, cefoperazone or moxalactam, and for 38 strains of the group d streptococci. the drug was very active against the most frequently encountered gram-nega ... | 1982 | 6818153 |
| [role of iron and a siderophore in the development of bacterial infections in the mouse: the study of two bacteria and three routes of inoculation]. | we have studied the influence of ferric iron and the influence of a siderophore on the lethal activity of two bacteria injected in mice intraperitoneally intravenously or orally. iron and the siderophore significatively increase the lethal activity of an avirulent bacteria, enterobacter cloacae, injected intraperitoneally or intravenously. the virulence of a bacteria pathogen for mice, salmonella typhimurium, is also increased when injected intraperitoneally. therefore we have noted a decrease i ... | 1982 | 6820299 |
| the in-vitro activity of o-demethylfortimicin. | the activity of o-demethylfortimicin against ampicillin, cefazolin and carbenicillin resistant bacteria was determined. o-demethylfortimicin showed excellent in-vitro activity against escherichia coli, klebsiella pneumoniae, enterobacter cloacae, ent. agglomerans, ent. aerogenes, citrobacter freundii, proteus vulgaris, morganella, and providencia inhibiting these organisms at less than or equal to 3.1 mg/l. it was particularly effective against ent. cloacae and serratia marcescens that were resi ... | 1983 | 6833173 |
| in vivo selection of resistance to multiple cephalosporins by enterobacter cloacae. | 1983 | 6833801 | |
| [spontaneous chylothorax in intensive therapy of a very low-weight newborn infant with septicemia caused by enterobacter cloacae]. | 1983 | 6835182 | |
| effect of hydrazines on substrate utilization by a strain of enterobacter cloacae. | 1983 | 6850140 | |
| transient bacteremia following endoscopic injection sclerotherapy of esophageal varices. | the incidence of transient bacteremia following endoscopic injection sclerotherapy of esophageal varices was evaluated in 18 patients subjected to 40 sessions of injection sclerotherapy. blood cultures were obtained before sclerotherapy and at five minutes, 30 minutes, and 24 hours after sclerotherapy. the injectors as well as the endoscope were cultured before and after the procedure. blood cultures were positive in two patients after injection sclerotherapy (enterobacter cloacae and staphyloco ... | 1983 | 6870408 |
| in vitro evaluation of the bactec resin-containing blood culture bottle. | the bactec resin-containing blood culture bottle (16b; johnston laboratories) was designed to bind antibiotics and to support bacterial growth. however, only modest increases in the recovery rates of pathogens have been found in clinical studies. this in vitro study evaluated the ability of the 16b to recover organisms from human serum containing clinically achievable concentrations of antibiotics. escherichia coli, enterobacter cloacae, klebsiella pneumoniae, pseudomonas aeruginosa, haemophilus ... | 1983 | 6874903 |
| comparative study of fosfomycin activity in mueller-hinton media and in tissues. | fosfomycin utilizes two uptake systems as ways of entry into microorganisms: the l-a-glycerophosphate and the hexose phosphate transport system. the latter is inducible by glucose-6-phosphate. the relationship between glucose-6-phosphate (concentration range 0-100 mg/l) and the susceptibility of staphylococcus aureus was studied in mueller-hinton broth. an almost maximal enhancement of fosfomycin activity was found at 25 mg/l glucose-6-phosphate. fosfomycin activity against staph. aureus, escher ... | 1983 | 6885678 |
| analysis of eight cases of neonatal meningitis and sepsis due to enterobacter sakazakii. | eight cases of neonatal meningitis due to enterobacter sakazakii (formerly known as yellow-pigmented enterobacter cloacae) which occurred in the netherlands during the last 6 years were investigated retrospectively. two patients had necrotizing enterocolitis and meningitis simultaneously. despite treatment (in most cases with ampicillin and gentamicin), the fatality rate was 75%. strains were much more susceptible to some of the new beta-lactam antibiotics than to ampicillin. a mode of transmiss ... | 1983 | 6885983 |
| retrospective analysis of plasmid patterns in a study of burn unit outbreaks of infection due to enterobacter cloacae. | to evaluate the usefulness of plasmid pattern analysis as an epidemiologic tool and to determine the mechanism of resistance to silver sulfadiazine and mafenide acetate, silver sulfadiazine-resistant, mafenide acetate-resistant enterobacter cloacae isolates from a 1976 outbreak of infections in a burn unit (group i) were analyzed retrospectively. these strains were compared with various e cloacae isolates (groups ii-v), including e cloacae isolates from a more recent (1982) burn unit outbreak (g ... | 1983 | 6886483 |
| laboratory diagnosis of bacteremia by headspace gas-liquid chromatography. | the growth of staphylococcus aureus, streptococcus pneumoniae, s. fecalis, s. sanguis, s. bovis, s. mitior, s. agalactiae, escherichia coli, a-d group, klebsiella aerogenes, k. oxytoca, enterobacter cloacae, proteus mirabilis, serratia marcescens, pasteurella multocida or listeria monocytogenes in 83 blood cultures was detected in a 1.5-min analysis using head-space gas-liquid chromatography. two hundred and twenty-four blood cultures in which there was no growth of micro-organisms were negative ... | 1983 | 6888963 |
| antagonism of carbenicillin and cefamandole by cefoxitin in treatment of experimental infections in mice. | the ability of cefoxitin to antagonize the in vivo efficacy of cefamandole and carbenicillin as predicted by in vitro assays was analyzed in experimental infections in mice. cefoxitin was administered in a nonprotective dose either at the time of challenge or simultaneously with the protective drug, 1 and 3.5 h postchallenge. in mice infected with enterobacter cloacae, median 50% protective doses of cefamandole and carbenicillin were markedly increased by cefoxitin, especially when the latter wa ... | 1982 | 6921959 |
| resistance types in enterobacter cloacae. occurrence and resistance to ampicillin, carbenicillin, cephalothin and mecillinam. transfer of ampicillin resistance. | an investigation of the resistance types in enterobacter cloacae is presented. the frequency of the different resistance types was determined. the strains were divided into three groups according to sensitivity to penicillin derivatives. the ampicillin-carbenicillin-sensitive (a-s/ca-s) group 1 comprised 20% of the e. cloacae strains received in this laboratory. the ampicillin resistant-carbenicillin-sensitive (a-r/ca-s) group 2 comprised 38.5% of the strains and the a-r/ca-r group 3 comprised 4 ... | 1982 | 6922669 |
| cefmenoxime (sce-1365), a novel broad-spectrum cephalosporin: in vitro and in vivo antibacterial activities. | the activity of cefmenoxime (sce-1365), 7 beta-[2-(2-aminothiazol-4-yl)-(z)-2-methoxyiminoacetamido]-3-[(1-methyl-1h-tetrazol-5-yl)thiomethyl]ceph-3-em-4-carboxylic acid, was compared with that of other cephalosporins. cefmenoxime exhibited high activity against a wide variety of gram-positive and gram-negative bacteria. the in vitro activity of cefmenoxime against streptococcus pyogenes, haemophilus influenzae, and enterobacteriaceae, including indole-positive proteus, serratia marcescens, ente ... | 1981 | 6941742 |
| in vitro antibacterial activity of fluorinated analogs of chloramphenicol and thiamphenicol. | we evaluated the in vitro antimicrobial activity of sch 24893, sch 25298, and sch 25393, three novel analogs of chloramphenicol and thiamphenicol. all of the analogs had minimal inhibitory concentrations of less than or equal to 10 micrograms/ml for 18 chloramphenicol-thiamphenicol-resistant strains of shigella dysenteriae and 21 strains of resistant salmonella typhi. the analogs were also more active than were chloramphenicol and thiamphenicol against chloramphenicol-resistant enteric bacteria, ... | 1981 | 6957162 |
| in vitro comparison of cefotetan with five other cephalosporins against nosocomial pathogens. | the in vitro activity of cefotetan against staphylococcus aureus and gram-negative bacterial strains including nonfermenting species has been compared with that of cefoxitin, cefotaxim, moxalactam, cefoperazone and ceftazidime by use of an agar dilution method. cefotetan was found to be inactive against pseudomonas aeruginosa and acinetobacter species and only moderately active against staphylococcus aureus, pseudomonas maltophilia, pseudomonas cepacia, and enterobacter cloacae. it was more acti ... | 1982 | 6958416 |