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mmpi changes in briefly hospitalized non-narcotic drug users.the minnesota multiphasic personality inventory (mmpi) was administered to 66 non-narcotic drug abusers as part of an intensive study of polydrug abuse. patients were classified into four primary drug-of-abuse groups using either stimulants, barbiturates, other sedative-hypnotics, or a combination of these drugs. it was readministered to 42 of these patients after 2 weeks' hospitalization. at admission, the group's mmpi profile was consistent with psychosis. at discharge, most of the mmpi t-scor ...200018551
large decompressive craniectomy in management of severe cerebral contusion. a review of 207 cases. 199991129
dried blood spot screening for cystic fibrosis. 197992637
acromegaly with normal growth-hormone levels and pituitary histology. case report.in rare cases, acromegalic patients have normal basal concentrations of growth hormone, and their acromegaly results from abnormal growth-hormone secretory patterns. a patient is reported with the clinical features of acromegaly, who had elevated somatomedin levels and an enlarged sella turcica, but whose serum growth-hormone levels on continuous monitoring were in the normal range, with levels of 2.8 to 8.9 ng/ml. dynamic studies of growth hormone revealed normal responses to hypo- and hypergly ...1998106097
cholinergic nerves in blood vessels of the female reproductive system.cholinergic innervation of the blood vessels of the female reproductive system was investigated in human by the cholinesterase method. the following results were obtained: 1. the uterine and vaginal arteries are provided with a rich cholinergic innervation. 2. the ovarian, tubaric and ovarian-uterine artery are poorly innervated. 3. the ovarian and uterine vein are not provided with a cholinergic innervation.1979120093
[effect of para-chlorophenylalanine and 5-hydroxytryptophan on the caudate nucleus in cats].in unrestrained cats parachlorophenylalanine, an inhibitor of serotonin synthesis, increased the thresholds of the contraversive reaction and arrest reaction accompanied by spindle-waves in the sensory-motor cortex in the stimulation of the rostro-ventral areas of the caudate nucleus. the reactions evoked from the dorso-medial areas of the head and the body of the nucleus changed differently. on the contrary, 5-hydroxytryptophane, serotonin precursor, increased most of the indices of the caudate ...1978149572
microvessel reactions and nad-nadh changes in cat brain cortex during cortical stimulation under normo- and hypercapnic conditions. 1977202240
[possible nature of negative cooperation in d-glyceraldehyde-3-phosphate dehydrogenase].some considerations concerning the detailed mechanism of negative cooperativity in gpd are proposed. the hypothesis represents a modification of the sequential model (koshland et al.) taking into account last experimental data about the binding of nad analogs and fragments. two main facts have been used as a basis for the model: 1. neither adp-ribose nor nicotinamide mononucleotide (nmn) fragments of nad show negative cooperative binding to gpd. 2. neither modifications of adenine and nicotinami ...1983221801
regulation of thymidine phosphorylation in nucleate and anucleate cells of acetabularia. 1977235130
affinity chromatography of putrescine oxidase from micrococcus rubens and spermidine dehydrogenase from serratia marcescens.putrescine oxidase [ec 1.4.3.4], putrescine : oxygen oxidoreductase (deaminating) (flavin-containing), from micrococcus rubens and spermidine dehydrogenase from serratia marcescens were adsorbed on amine-sepharose 4b in which one of the terminal amino groups of diamine or triamine was covalently bound to sepharose 4b leaving the other terminal amino group(s) free. the affinities of these enzymes for the amine-sepharose 4b increased on increasing the chain length of the methylene groups in the im ...1979376502
[the incidence of abnormal eeg patterns with clozapine therapy (author's transl)].during treatment with clozapine 59% of 127 patients showed abnormal eegs. remarkable are paroxysmal disturbances with sharp waves and/or sw-pattern in ca. 13%. generalized tonic-clonic convulsive cereberal seizures were observed only twice.2004383098
psychiatric morbidity and pregnancy: a controlled study of 263 semi-rural ugandan women.two hundred and sixty three pregnant ugandan women and 89 non-pregnant, non-puerperal women were interviewed using a semi-structured psychiatric questionnaire. comparison of psychiatric morbidity between the control group and matched pregnant women showed an increased frequency of psychiatric morbidity in pregnant women. separated pregnant women were particularly at risk. no association was found between antenatal psychiatric morbidity and age, gravidity, number of co-wives or the duration of th ...2004444790
substrate specificity and reaction mechanism of putrescine oxidase.putrescine oxidase [ec 1.4.3.4] of micrococcus rubens oxidizes many kinds of synthetic polyamines: triamines (spermidine types), tetramines (spermine types), and n-substituted putrescines. polyamines possessing terminal 4-aminobutylimino groups in their structures were more active as substrates. putreanine was oxidized at a rate comparable to that of putrescine, and was converted to 1-pyrroline and beta=alanine. activities and km values for polyamines were affected by the substituent attached to ...1979479133
[choroid plexus carcinoma with metastasis to bone (author's transl)].a very rare case of the choroid plexus carcinoma of the left lateral ventricle with metastasis to bone was reported. a two-month-old baby was suffering from irritability and vomiting. her vital signs became progressively worse. on admission she showed an increased head circumference and meningeal irritation signs. an emergency tapping of the right lateral ventricle at the anterior fontanel revealed the bloody csf and an opening pressure of over 700 mm of water. all laboratory findings were negat ...2004492463
stenosing tenovaginitis affecting the tendon of extensor digiti minimi at the wrist.we report a patient with stenosing tenovaginitis affecting the sheath of the tendon of extensor digiti minimi. the similarities to typical de quervain's disease are discussed.2004520874
[ultrasonic localization for closed renal biopsy]. 2004520913
mineralocorticoid potentiation of isoproterenol-induced myocardial injury: ultrastructural equivalent. 1979522137
[melanin and melanosomes occurring in the central nervous system in comparison to their extracerebral manifestations and to synthetic melanin derived from dopamine and serotonin (author's transl)]. 1979525259
photokilling of micrococcus roseus. 1977594175
specific antibodies to the n-termini of the interpeptide bridges of peptidoglycan.the synthetic peptides gly5-epsilon-ahx and l-ala3-epsilon-ahx, with structural similarity to the interpeptide bridge peptides of staphylococci or micrococci, respectively, were convalently linked to human serum albumin via their carboxylgroups. antisera to these synthetic peptidyl-protein antigens contained fairly high amounts of antibodies with specificity to the n-terminal parts of the peptide chains attached to the carrier proteins. antisera to (gly5-epsilon-ahx)20-albumin gave, without exce ...1978697508
interconversion of large packets and small groups of cells of micrococcus rubens: dependence upon magnesium and phosphate.micrococcus rubens, a gram-positive occus, usually forms large, cubic packets of more than 500 cells that are regularly arranged in three-dimensional cell groups. in medium with extremely low concentration of mg2+ and phosphate, in which the cells can only grow on a agar surface, it formed small groups of 2 to 20 cells. irregularly arraged cell groups of intermediated size were obtained in culture media containing intermediated concentrations of mg2+ and phosphate. mutants that formed irregular ...1977845123
minimal requirements in defined media for improved growth of some radio-resistant pink tetracocci.defined media permitting extensive growth of representative pink radio-resistant tetracocci (micrococcus radiodurans, micrococcus roseus, and micrococcus radiophilus) and two controls (an ultraviolet-sensitive mutant of m. radiodurans and micrococcus luteus) are described. availability of fe (especially fe3+) proved essential for good growth, as evidenced by (i) favorable effects of hydroxamic acids, e.g., salicylhydroxamic acid, and (ii) the growth promotion by hemin when joined with elevated c ...1977879774
[dependence on metaquolone-diphenyldramine combination]. 20051180723
familial occurrence of bilateral intracranial occlusion of the internal carotid arteries (moya moya).in a family of 14 brothers and sisters, 3 cases of occlusive disease of the large intracranial vessels (moya moya) were found. each of the three had one or more cerebrovascular attacks and a typical cerebral angiogram. eight other members of the family had severe headaches. angiography was carried out in three of these with normal findings.20051181815
action of visible light on enzymes in cell envelopes of micrococcus roseus. 19751208657
[drug addiction behavior in its relationship with suicidal behavior]. 20051233895
mechanism of action of putrescine oxidase. binding characteristics of the active site of putrescine oxidase from micrococcus rubens.putrescine oxidase (ec 1.4.3.4), putrescine: oxygen oxidoreductase (deaminating) (flavin containing), has been found to form complexes with a variety of amines. with few exceptions these compounds competitively inhibit putrescine oxidation and also perturb the visible absorption spectrum of the enzyme (i.e., the spectrum due to fad). inhibition constants are reported for a number of amines; the presence of a cationic amino group in the inhibitors appears to be the structural feature essential fo ...19761260033
ige-secreting cells in the thymus: correlation with induction of tolerance to ige.we have shown previously that normal mice become tolerant to endogenous ige when they are approximately 2 weeks old and that this corresponds closely with the initial appearance of ige in serum. tolerance evidently is restricted to t cells, since b cells responsive to ige are present in neonatal and adult mice. the present report shows that ige-secreting cells can be detected in the thymus between days 7 and 11 after birth and that the onset of tolerance to ige occurs at the age of 11 days. simi ...20061594629
the major carotenoid pigment of a psychrotrophic micrococcus roseus strain: purification, structure, and interaction with synthetic membranes.the major carotenoid pigment of a psychrotrophic micrococcus roseus strain was purified to homogeneity from methanol extracts of dried cells by reverse-phase liquid chromatography and was designated p-3. on the basis of the uv-visible, infrared, mass, and 1h nuclear magnetic resonance spectra of p-3, it was identified as bisdehydro-beta-carotene-2-carboxylic acid. the pigment interacted with synthetic membranes of phosphatidylcholine and dimyristoyl phosphatidylcholine and stabilized the membran ...19911744046
[surgical laparoscopy--minimally invasive surgery]. 20071829132
neurilemmoma of the intrathoracic vagus nerve.a neurilemmoma (schwannoma) of the left intrathoracic vagus nerve was discovered on a chest radiograph of a 28 yr old woman and was removed via a left thoracotomy. although neurogenic tumours are the most common tumours of the mediastinum, they rarely involve the intrathoracic vagus nerve.20071855582
[polyamines in representative taxa of coryneform and other bacteria].the composition of polyamines is studied for the first time in representatives of the genus micrococcus and taxon "conglomeratus", strains staphylococcus aureus ccm 209, deinococcus erythromyxa ccm 706 as well as of erwinia carotovora atcc 15713 polyamines, which are not extracted by perchloric acid. considerable amounts of spermine and rarely of spermidine are revealed in cells of gram positive microorganisms, that differs them from gram negative bacteria possessing high concentrations of putre ...19902115965
quality control practices in centralized tumor registries in north america.a survey of quality control practices was mailed to 73 central registries in the u.s. and canada. the response rate was 88%, with respondents representing a wide range of registry characteristics and reporting strategies. while registries expressed different priorities in data use, 80% of respondents felt quality control data were important in the identification of problems. the most common method of quality control was acceptance sampling (used by 97% of respondents), and took the form of visua ...20082243256
effect of synexin on aggregation and fusion of chromaffin granule ghosts at ph 6.fusion of chromaffin granule ghosts was induced by synexin at ph 6, 37 degrees c, in the presence of 10(-7) m ca2+. to study the kinetics and extent of this fusion process we employed two assays that monitored continuously mixing of aqueous contents or membrane mixing by fluorescence intensity increases. in both assays chromaffin granule ghosts were either labeled on the membrane or in the included aqueous phase. the ratios of blank to labeled chromaffin granule ghosts were varied from 1 to 10. ...19872443172
hiv-2 in west africa in 1966. 19892566074
complications of intracranial bypass for vertebrobasilar insufficiency.the authors' initial experience with intracranial revascularization of vertebrobasilar insufficiency, reported previously, fortunately yielded reasonably good results with high patency rates but in some cases there were significant, albeit temporary, complications. since that time, major brain-stem strokes have occurred in two patients following superficial temporal to superior cerebellar artery bypass procedures. this occurrence has caused the authors to reassess their experience with this proc ...20082643687
complications of intracranial bypass for vertebrobasilar insufficiency.the authors' initial experience with intracranial revascularization of vertebrobasilar insufficiency, reported previously, fortunately yielded reasonably good results with high patency rates but in some cases there were significant, albeit temporary, complications. since that time, major brain-stem strokes have occurred in two patients following superficial temporal to superior cerebellar artery bypass procedures. this occurrence has caused the authors to reassess their experience with this proc ...20082643687
review of european clinical experience with fenofibrate.since the introduction of fenofibrate to european clinical practice in 1975, some 6.5 million patient-years of experience in the treatment of hyperlipidemia have been accumulated. a review of results of clinical trials shows fenofibrate to have a broad spectrum of lipid-lowering activity, reducing the total cholesterol level by 20-25% in type iia patients and triglycerides by 40-60% in type iib and iv patients. high levels of low-density lipoprotein cholesterol are reduced and, where low at base ...20082653620
lymphoma phenotyping in formalin-fixed and paraffin wax-embedded tissues. i. range of antibodies and staining patterns.recently, monoclonal antibodies capable of phenotyping malignant lymphomas in routinely fixed and processed tissue have become available. some of these reagents identify lineage-restricted variants of the leucocyte common molecule, whereas others identify unique fixation-resistant epitopes on lymphoid cells, some of which are shared by non-lymphoid tissues. a new generation of antibodies recognizing 'classical' leucocyte antigens such as cd3 are also emerging. refinements in antigen detection sy ...20082661395
detection of messenger rna in routinely processed tissue sections with biotinylated oligonucleotide probes.in situ hybridization (ish) with a radioactively 35s-labeled probe and a biotinylated oligonucleotide probe for human calcitonin was used to analyze eight cases of medullary thyroid carcinoma (mtc) in paraffin sections. three of these cases were also studied with frozen tissue sections. the biotinylated probe readily detected calcitonin messenger rna (mrna) in routinely processed formalin-fixed paraffin-embedded tissue section within 24 hours. northern hybridization and other control studies dem ...19892756933
in-vitro release of [14c]glutamate from dentate gyrus is modulated by gaba.the effect of gaba (10(-3) and 10(-4) m) on the release of preloaded [14c]glutamate from slices of rat dentate gyrus, in response to k+ stimulation, was studied in ca2+-free and normal krebs solutions. release in ca2+-free solution was significantly enhanced, but there was no change in release in normal krebs solution. these results imply that ca2+-dependent (presumably neuronal) release of glutamate from the dentate gyrus is depressed by gaba, while non-neuronal ca2+-independent release is enha ...19862872320
tannin is the major agent present in cotton mill dust responsible for human platelet 5-hydroxytryptamine secretion and thromboxane formation. 19862875226
changes in renal functions during beta-blocker carazolol administration in acute heat-stressed pigs. 19872890402
specific antibodies reveal ordered and cell-cycle-related use of histone-h4 acetylation sites in mammalian cells.antibodies specific for the acetylated forms of histone h4 (h4) were produced in rabbits with a synthetic peptide corresponding to the 18 n-terminal residues of tetra-acetylated h4 (i.e. with acetyllysine at positions 5, 8, 12 and 16). specificity was determined by inhibition assays using four additional peptides, each acetylated at only a single site. using an antiserum (r6) specific for the acetylation site at lys-5 we have estimated the proportion of lys-5 sites acetylated in the mono-, di- a ...19892917555
adrenergic receptors: possible mechanism of inverse regulation of alpha- and beta-receptors.many physiologic and pathologic conditions, including bronchial asthma, are associated with inverse changes in alpha- and beta-receptor-mediated responses in various tissues. the direction of the change elicited by a given stimulus is tissue specific, as exemplified by the actions of thyroid hormones: in the rat heart, hypothyroidism reduces beta- and increases alpha-receptor responses, whereas in the rat liver it has the opposite effects. a similar increase in beta- and decrease in alpha-recept ...19852991359
potentiation of cholinergic tone by pyridostigmine bromide re-instates and potentiates the growth hormone responsiveness to intermittent administration of growth hormone-releasing factor in man.it is known that in normal subjects repeated administration of the growth hormone-releasing factor (grf) induces a state of partial refractoriness of the somatotropes to grf. studies were conducted to verify whether the cholinergic system plays a role in the mechanism(s) underlying the reduced gh responsiveness to the neuropeptide. in five healthy men, the gh response to three consecutive injections of grf (50 micrograms iv), administered at 2 h intervals, was considerably blunted after the seco ...19863020850
prenatal diagnosis of fabry's disease by direct analysis of chorionic villi.six pregnancies of three carriers for x-linked fabry's disease, were monitored by chromosome and enzyme analysis. two affected male fetuses were detected by the demonstration of alpha-galactosidase deficiency in amniotic fluid cells and chorionic villi respectively. the use of chorionic villi enabled a diagnosis within a few hours after sampling in the ninth week of pregnancy whereas the use of amniotic fluid cells in the earlier case required two weeks of culturing after amniocentesis in the 16 ...20033035532
complicated migraine: case report.the occurrence of long lasting focal neurological deficit as a complication of migraine is well known. a high incidence of c.t. scan abnormalities have been seen in subjects affected by severe complicated migraine; in some cases such lesions had the aspect of cerebral infarction. in this report we will relate case of a 29 year old woman with complicated migraine and multifocal suffering within the area of the hind brain circulation. the hypodense area we found with c.t. in the left cerebellar he ...20103042690
complicated migraine: case report.the occurrence of long lasting focal neurological deficit as a complication of migraine is well known. a high incidence of c.t. scan abnormalities have been seen in subjects affected by severe complicated migraine; in some cases such lesions had the aspect of cerebral infarction. in this report we will relate case of a 29 year old woman with complicated migraine and multifocal suffering within the area of the hind brain circulation. the hypodense area we found with c.t. in the left cerebellar he ...20103042690
dental care for seniors. 20113063356
immunogenic activity of gonococcal protein i in mice with three different lipoidal adjuvants delivered in liposomes and in complexes.for several reasons the major outer membrane protein from neisseria gonorrhoeae (gonococcal protein [pi]) is an attractive component for a gonococcal vaccine. this paper describes the influence of two different physical forms of pi on its immunogenic activity. to this end pi was delivered in liposomes and in protein-detergent complexes. in both forms pi was present in a multimeric form. the liposomes were composed of phosphatidylcholine and cholesterol. the effect of dicetylphosphate as a negati ...19863095239
bioaffinity sensors. 20113131631
hypoglycemia induced by co-trimoxazole in aids. 20113147758
rat catcher's warfarin treatment associated with rectal haemorrhage. 19883147777
experimental infection of sheep and goats with muellerius capillaris (protostrongylidae, nematoda). 19883188728
laryngo-tracheo-bronchial foreign bodies in children.inhalation of a foreign body into the respiratory passage can be a serious and sometimes fatal childhood accident. in this paper we analyse the management of 223 children with laryngo-tracheo-bronchial foreign bodies. children below three years of age were found to be the most vulnerable. the majority of the patients were boys. over a quarter of the patients did not present with a history of inhalation. only 52 per cent reported within 24 hours of inhalation. endoscopic removal was possible in a ...20113209937
a ten years follow-up of the results of surgery for dupuytren's disease. a study of fifty-eight cases.fifty-eight patients (52 males and 6 females) operated on for dupuytren contracture were examined by the same author with a more than ten year follow-up. at time of surgery the average was 55 years old. 69 hands (169 fingers) rated 4.33 according to the simplified tubiana's score were treated by the same operative procedure: mac indoe's incision, digital z plasty (if needed), subtotal fasciectomy and physiotherapy beginning 8 days postoperatively. at long term, recurrence appears for 49 hands (7 ...20113233038
comparison of methods of carbamazepine dosage, individualization in epileptic patients.the aim of the present work was to analyse the predictive capacity of different optimization methods for carbamazepine dosage regimens according to population pharmacokinetic parameters and/or serum levels data. calculations were performed using a multiple non-linear regression program (multi 2 bayes) with two different options: (a) using the ordinary least squares methods and (b) the least squares method based on the bayesian algorithm. the predictive capacity of the three methods was analysed ...20113235481
comparison of methods of carbamazepine dosage, individualization in epileptic patients.the aim of the present work was to analyse the predictive capacity of different optimization methods for carbamazepine dosage regimens according to population pharmacokinetic parameters and/or serum levels data. calculations were performed using a multiple non-linear regression program (multi 2 bayes) with two different options: (a) using the ordinary least squares methods and (b) the least squares method based on the bayesian algorithm. the predictive capacity of the three methods was analysed ...20113235481
[tns in peripheral circulatory disorders]. 20123264599
morphological evidence of innervation of taste buds of rat fungiform papillae after acute x-ray irradiation.an acute dose of 2000 roentgens (r) of x-ray was delivered to the head and neck area of sprague-dawley rats. groups of rats were sacrificed at 0, 3, 7, 14, 21 and 30 days after x-ray irradiation. both general nerve staining and localization of cholinergic nerves by special staining of fungiform papillae were performed. no apparent change in number and distribution of nerve fibres were observed light microscopically within the fungiform papillae containing normal, degenerating and regenerating ta ...19873270572
reconstruction of microtia with conchal remnant.in microtia with conchal remnant (type b microtia), there are various degrees of deformity; consequently, different surgical procedures are required for individual cases. to clarify and simplify these complicated surgical techniques, type b microtia is divided into two types, type bi and type bii, from the standpoint of the emphasis on conchal creation. the methods of treatment are discussed.20123273009
[in memory of prof. ivan stanek. a contribution on the commemoration of his 70th birthday]. 20123307198
genetic factors in toxicology: implications for toxicological screening.methods of assessing the toxicity of xenobiotics have improved substantially during the last decade. however, as compounds become generally safer, the problem of individual variation in response assumes increasing relative importance. environmental factors such as age, health and nutritional status, and interactions with other xenobiotics account for some of this variation, but genetic differences between individuals and races have important implications. in a few cases, mendelian loci which con ...19873311639
jakob erdheim. eminent pathologist of vienna. 20123318534
effects of isoflurane on myocardial metabolism during postischaemic reperfusion in the rat.in experiments on isolated rat heart lung preparation, the effects of isoflurane on myocardial metabolism during postischaemic reperfusion were evaluated with intramyocardial high energy phosphates, lactate and glycogen. hearts were perfused for 10 min initially and made globally ischaemic for 8 min in ischaemic groups. afterwards, they were reperfused for 12 min. isoflurane was administered from 5 min after the start of perfusion to the end of reperfusion. there was no significant difference in ...19883364145
bilirubin, intraventricular hemorrhage, and phenobarbital in very low birth weight babies.the relationships among serum bilirubin concentration on days 5 and 7, birth weight, the presence of intraventricular hemorrhage, and the receipt of phenobarbital were examined in a group of 232 newborns weighing less than 1,751 g who were intubated, mechanically ventilated by 12 hours after birth, and whose parents had given permission for a randomized trial of phenobarbital prophylaxis of intraventricular hemorrhage. the ratio of serum bilirubin concentration to birth weight (the bilirubin div ...20123405664
the post-polio syndrome. 20123457467
growth-enhancing effects of culture filtrates of sputum isolates on the l-forms of haemophilus influenzae.the growth-enhancing effects of culture filtrates of respiratory pathogenic bacteria, including haemophilus influenzae, as well as normal floral bacteria other than neisseria perflava and branhamella catarrhalis on l-forms of h. influenzae were examined in vitro, using five species of major respiratory pathogenic bacteria and seven species of normal floral bacteria commonly isolated from the sputum of patients with chronic respiratory tract infections. the growth-enhancing factor(s) was present ...19863490016
the possible pitfalls of the measurement of intracellular calcium concentration of lymphocytes with the fluorescent indicator quin2.the measurement of intracellular calcium concentration of small cells became feasible and relatively easily accomplishable following the development of the fluorescent calcium chelating dye, quin2, by r. y. tsien and his co-workers. the present paper gives an experimental survey of the major possible pitfalls of the method such as: 1) the improper choosing of the concentration of quin2/am, 2) the misinterpretation of the calibration procedure, 3) the accidental heavy metal traces in the medium, ...19873500116
a novel glycosphingolipid that may participate in embryo inversion in volvox carteri.mouse monoclonal antibody 4-i-244 detects a developmentally regulated antigen in embryos of volvox carteri and inhibits specifically the morphogenetic process of inversion (the process by which the embryo turns inside out). antigen 4-i-244 was chemically characterized as a complex phytosphingolipid containing the neutral sugars xylose, galactose, and glucose as well as inositol and phosphate.19863524860
[angiography and digital subtraction angiography].in pediatrics angiography is a method that is used relatively rarely. during the last few years the introduction of nonionic contrast media has led to considerable progress in the field of conventional angiography since these contrast media are tolerated much better than the ionic ones. also in the field of catheter techniques the introduction of new catheters has led to considerable progress. the new catheters are characterized by very thin walls and wide lumina which allow a high flow of contr ...20123528821
retraction of publications. 20133545676
estrogen dose-response relationship. 20133568542
polyunsaturated fatty acids augment free radical generation in tumor cells in vitro.polyunsaturated fatty acids (pufas) have been shown to inhibit both normal and tumor cell growth in vitro. as pufas are known to induce a respiratory burst and free radical generation in polymorphonuclear leukocytes and since free radicals are toxic to cells, we investigated the effect of pufas on a measure of free radical generation (nitroblue tetrazolium reduction) in normal human fibroblasts and breast cancer cells in vitro. results suggested that linoleate (la), gamma-linolenate (gla), arach ...19873593336
comparative evaluation of the immediate and sustained antibacterial action of two regimens, based on triclosan- and chlorhexidine-containing handwash preparations, on volunteers.the degerming effect of a 3 min handwash with 2% triclosan, or 4% chlorhexidine, in detergent and enhanced efficacy of either antiseptic in isopropyl alcohol, was evaluated in volunteers. handwashing with either antiseptic preparation reduced the normal flora by a factor of 10; alcohol rubbing by approximately a factor of 1000. both regimens eliminated micrococcus roseus, artificially inoculated before every procedure. the sustained action of the same detergent preparations was further studied i ...19873595750
the effect of heat upon the interaction between aminoglycosides and semi-synthetic penicillins in human serum: a consideration for hiv infectious serum.we conducted 2 experiments to study the effect of heat on the interaction between aminoglycosides and semi-synthetic penicillins in human serum. in one experiment, human serum spiked with either gentamicin or tobramycin at a concentration of 4.7 mg/l plus carbenicillin, ticarcillin, piperacillin, mezlocillin, or azlocillin at concentrations of either 50 mg/l or 150 mg/l was subjected to a 30-min, 56 degrees c waterbath incubation. in the second experiment, randomly selected sera from patients re ...19873649918
[assistance of aged patients at meal time]. 20133650433
a rapid enzymatic assay for total blood polyamines.we have designed a rapid, reliable enzymatic assay for total blood polyamines, as based on the combination of substrate specificity of polyamine oxidase (pao) from aspergillus terreus and putrescine oxidase (puo) from micrococcus rubens. quinone dye, derived from hydrogen peroxide generated in the oxidation reaction, is measured spectrophotometrically at 555 nm, and total amounts of putrescine (put), cadaverine (cad), spermidine (spd), and spermine (spm) can be readily determined. the minimum de ...19873652436
comparative study in exercise tolerance between vvi and activity-sensing rate-responsive pacing. 20123678256
physician attitudes toward office based non-pharmacological treatment of anxiety.despite evidence indicating the effectiveness of behavioral techniques in treating anxiety symptoms and disorders, treatment of anxiety in the medical setting has tended to be largely pharmacological. this research project investigates the attitudes of a sample of practicing physicians toward utilization within their practices of non-pharmacological approaches in the treatment of anxiety.20133678679
[surgical treatment of enzymatic cholecystitis]. 20133695320
demonstration of sensory innervation of rat tongue with anterogradely transported horseradish peroxidase.wheat germ agglutinin-horseradish peroxidase injected into the petrosal ganglion in rats was transported to the posterior tongue in the glossopharyngeal nerve. labelled fibers innervated the ipsilateral foliate papilla only, but both ipsi-and contralateral sides of the single circumvallate papilla. somatosensory fibers in the posterior tongue also were labelled. label crossed transcellularly from the afferent fibers into taste bud cells. use of this method provides more detailed knowledge of sen ...19863697712
[propranolol poisoning]. 20133703028
cohabitation, convergence, and environmental covariances.temporal variation in traits has long been a central theme in epidemiology. however, human geneticists have largely avoided this topic. recently, several authors have shown how temporal variation in relative-to-relative covariances can be accommodated within the framework of variance components analysis. the present paper attempts to clarify the mathematics implicit in their approach. a stochastic mechanism is discussed that causes covariances to converge or diverge exponentially fast as relativ ...19863728567
roles of retinal periphery and depth periphery in linear vection and visual control of standing in humans. 20113730954
[postoperative radiotherapy of supratentorial anaplastic glioma].between 1970 and 1983, 149 patients with high grade anaplastic supratentorial gliomas received a postoperative irradiation during primary treatment. 118 out of these patients had an anaplastic astrocytoma, 18 an anaplastic oligodendroglioma, and 13 an anaplastic ependymoma. most of these patients were treated by irradiation of a great volume with 50 gy within five weeks, the others by irradiation of the total brain with 50 gy within five weeks and saturation with 10 gy within one week. the one-y ...20123738736
significance of the dog as 'second animal species' in toxicity testing for establishing the lowest 'no-toxic-effect level'.the toxicity data of 66 compounds adequately tested in the rat (as 'prime animal species') and in the dog (as 'second animal species') were studied to find out for how many of these compounds the study in dogs led to a lower 'no-toxic-effect level' (ntel) than that found in the rat. from a quantitative point of view such information would contribute to a better insight into the desirability of toxicity studies in dogs, because acceptable daily intakes and permissible exposure levels in man are g ...19863760453
[endometriosis causing intestinal stenosis]. 20133787802
local anaesthetics. iv--synthesis and activity of 2-(n-substituted or n,n-disubstituted aminoacetamido)-4- or -4,5-substituted thiazoles.synthesis is described of eleven new 2-(n-substituted or n,n-disubstituted aminoacetamido)-4- or -4,5-substituted thiazoles (i). their hydrochlorides were screened for local anaesthetic activity on frogs by the sciatic plexus method and the activity compared with that of procaine.20133792539
a comparative study of the allergenicity of quaternary ammonium compounds in guinea-pigs. 19863815891
[the art of plain talk. the psychiatric nurse in conversation]. 20133852562
[immunological reactivity of patients with suppurative lung diseases and the effectiveness of immunocorrective therapy].patients with acute lung abscesses and bronchiectatic diseases manifested deep changes in the immune responsiveness, which were largely of compensatory (elevation of iga content to over 2 mg/ml), immunosuppressive (decrease of lymphocyte blast transformation with pha down to 52.2 and 48.6%) or autoimmune (increase of spontaneous lymphocyte blast transformation up to 8%) character. in patients with acute lung abscesses, the indicators enumerated tended during treatment toward normalization which ...20123873719
5-oxo-l-prolinase from rat kidney. 19853911006
properties of a mutant lactose carrier of escherichia coli with a cys148----ser148 substitution.the cysteine residue at position 148 in the lactose carrier protein of escherichia coli has been replaced by serine using oligonucleotide-directed, site-specific mutagenesis of the lac y gene. the mutant carrier is incorporated into the cytoplasmic membrane to the same extent as the wild-type carrier, confers a lactose-positive phenotype on cells, and actively transports lactose and other galactosides. however, the maximum rate of transport for several substrates is reduced by a factor of 6-10 w ...19853922794
idiopathic haemochromatosis and eye symptoms. a case report.a 61-year-old man with idiopathic haemochromatosis and eye symptoms is described. the examination showed microaneurysms scattered over the bulbar conjunctiva, and some discrete pigmentations in the superficial tissue in the perilimbal area. each cornea revealed a light brown, ellipsoid opacity with the longest diameter horizontally, seemingly being located in the corneal epithelium and/or the anterior part of the stroma. a corneal biopsy was examined by light and electron microscopy. two differe ...19853923775
cytogenetic study in six spanish patients with burkitt's lymphoma.a cytogenetic study carried out on affected tissues of six children with burkitt's lymphoma revealed five cases with a typical translocation (8q-; 14q+) and one with a variant t(2p-; 8q+). additional cytogenetic variations were present in three cases. one had two acrocentric marker chromosomes comprised of material from chromosome #1 (1q21----q44) translocated to the y gonosome. the other two cases had a cytogenetic alteration of chromosome #12. cytogenetic studies carried out systematically in ...19853967210
an enzymatic differential assay for urinary diamines, spermidine, and spermine.subsequent to the hydrolysis of urinary conjugated amines by heating with hydrochloric acid, free amines were isolated by cation-exchange chromatography. spd and spm in an aliquot of amine extract were first oxidized by pao from penicillium chrysogenum, producing put and hydrogen peroxide. dias, which consist of the initially present dias plus put produced by pao, were subsequently oxidized by puo from micrococcus rubens, producing hydrogen peroxide. in an another aliquot of the amine extract di ...19853980559
[partial splenic resections and nd-yag laser].eleven partial splenectomies are performed in pigs. simultaneous section and hemostasis are obtained with continuous 80 w power shoot. there is no hemorrhagic or septic complication and normal splenic weight is recovered in 5 months. platelets elevation observed in post-operative. platelets elevation observed in post-operative period returns to normal rate between 20th and 30th day. acute cellular damage of cut splenic edge does not exceed 3 mm in thickness. semi-thick and electron microscopic e ...19853997982
the response of the apparent receptive speech disorder of parkinsonism to speech therapy. 20144009199
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