Publications

the polysaccharide capsule of bacteroides fragilis subspecies fragilis: immunochemical and morphologic definition.	a large-molecular-weight capsular polysaccharide was isolated from strains of bacteroides fragilis subspecies fragilis. by means of electron microscopy and staining with ruthenium red, the thick polysaccharide capsule was also visualized. with use of a radioactive antigen-binding assay, antibody to this capsular polysaccharide was demonstrated in antisera prepared in rabbits to each of eight strains of b. fragilis fragilis. antibody of similar specificity was not found in antisera prepared to ba ...	1976	1451
survival of anaerobic bacteria during transportation. 1. experimental investigations on the effect of evacuation of atmospheric air by flushing with carbon dioxide and nitrogen.	the effect of evacuation of atmospheric air during transportation on recovery of anaerobic bacteria was investigated. evacuation of atmospheric air from glass tubes by flushing with pure carbon dioxide lowered the content of oxygen to about 0.4 per cent. three b. fragilis strains and one strain of fusobacterium mortiferum and of peptostreptococcus anaerobius were investigated. bacterial recovery was determined one hour and 24 hours after evacuation of atmospheric air by pure carbon dioxide and p ...	1976	3089
in vitro susceptibility studies with josamycin and erythromycin.	the in vitro activity of josamycin and erythromycin against five bacterial species was compared. in general, erythromycin was slightly more active by weight than josamycin, although both agents had a similar range of activity.	1976	4012
in vitro activity of josamycin against aerobic gram-positive cocci and anaerobes.	josamycin, a new macrolide antibiotic, was compared with ampicillin, erythromycin, and clindamycin in vitro against 25 isolates each of pneumococci, enterococci, staphylococcus aureus, s. epidermidis, and nonenterococcal hemolytic streptococci and against 25 anaerobes including 10 bacteroides fragilis. minimal inhibitory concentration and minimal bactericidal concentration data were obtained for the aerobic organisms, using serial twofold tube dilutions in mueller-hinton broth. minimal inhibitor ...	1976	7189
formation of beta-lactamase in bacteroides fragilis: cell-bound and extracellular activity.	nine strains of bacteroides fragilis were cultivated in stirred fermentors and tested for their ability to produce beta-lactamase. there was a correlation between formation of beta-lactamase and high values of the minimal inhibitory concentration against beta-lactam antibiotics. b. fragilis strain b70 was used for optimizing the production of beta-lactamase. the highest bacterial yield was obtained in a proteose peptone-yeast extract medium. optimal conditions for growth and beta-lactamase produ ...	1976	7997
bacterial interference by oropharynegeal and clinical isolates of anaerobic bacteria.	anaerobic isolates were tested for bacterial inhibitory activity. of 144 isolates, 102 were from oropharynegeal washings, and 42 were from clinical specimens. thirteen facultative bacterial species (seven members of the enterobacteriaceae and six species of gram-positive cocci) were used as indicators of inhibition. eleven anaerobic species were isolated from oral secretions. all isolates of bacteroides melaninogenicus, the most commonly recovered species, consistently inhibited several species ...	1976	10336
purification and characterization of bile salt hydrolase from bacteroides fragilis subsp. fragilis.	a high-molecular-weight (250 000) bile salt hydrolase (cholylglycine hydrolase, ec 3.5.-.-) was isolated and purified 128-fold from the "spheroplast lysate" fraction prepared from bacteroids fragilis subsp. fragilis atcc 25285. the intact enzyme had a molecular weight of approx. 250 000 as determined by gel infiltration chromatography. one major protein band, corresponding to a molecular weight of 32 500, was observed on 7% sodium dodecyl sulfate polyacrylamide gel electrophoresis of pooled frac ...	1976	10993
susceptibility of phosphomycin as a differential character for gram negative anaerobic bacilli.		1976	11203
activity of spectinomycin against anaerobes.	the in vitro inhibitory activity of spectinomycin was tested against various anaerobic bacteria. different results were obtained with different media and with different initial ph's of the media. the highest minimum inhibitory concentrations for bacteroides fragilis (formula: see text 128 mug/ml) were obtained with the use of wilkins-chalgren agar (ph 7.2) and brucella blood agar (ph 7.0). brucella blood agar at higher ph's (7.4 and 8.0) and mueller-hinton and diagnostic sensitivity test agars p ...	1977	18985
antimicrobial activity of human ascitic fluid.		1977	19339
chemical composition, serological reactivity and endotoxicity of lipopolysaccharides extracted in different ways from bacteroides fragilis, bacteroides melaninogenicus and bacteroides oralis.	lipopolysaccharides (lps) extracted from strains of bacteroides fragilis, bacteroides melaninogenicus and bacteroides oralis with phenol-water, trichloroacetic acid, edta or liquid phenol-chloroform-petroleum ether (pcp) and isolated by ultracentrifugation, varied considerably in their quantitative chemical composition. negligible yields of lps were obtained by pcp-extraction. all preparations were more or less serologically active. all methods (except pcp) extracted the same o-antigenic determi ...	1977	19922
effect of contrast media on the rate of oxidation of nadp.h and nad.h by rat liver microsomes.	the effect of roentgen-contrast media on the activity of the nadp'n and nad'n-dependent electron-transport chains of the rats liver microsomes was studied. bilignost, cardiotrast, triiotrast and triombrin are shown to lower the rate of the nadp'n oxidation by the rats' liver microsomes and have no effect (except for triiotrast) upon the rate of the nad'n oxidation. it is presumed that the relative resistance of the nad'n-specific flavoproteid is due to the presence of a hydrophobic layer impervi ...	1977	20329
comparison of the ribonucleoproteins of different rabies virus serotypes by radioimmunoassay.	radioimmunoassay (ria) provides a sensitive serological procedure for detecting rabies virus ribonucleoprotein (rnp) as well as its specific antibodies, ria was carried out using highly purified rnps labelled by the chloramine-t method. this paper describes optimal conditions for iodination of rnp with high specific activity. the optimal concentrations of 125i, rnp, chloramine-t, and reducing agent as well as the effect of ph on the reaction were investigated. ria proved to be extremely sensitiv ...	1977	22569
current aspects of gas gangrene, apropos of 47 cases collected over a 3-year period (1974-1976).	on the basis of 47 cases of gas gangrene collected over the three year period between 1974 and 1976, the authors review the circumstances surrounding its development, the clinical features and the prognosis of the disorder which remains grave despite a well-defined therapeutic protocol combining surgery, antibiotics and hyperbaric oxygen. there would appear to be a real resurgence of the disease at the present time. post-traumatic and surgical aetiologies predominate, giving rise to two types of ...	1977	23023
bacteroides fragilis septicemia.	on the basis of eight cases of bacteroides fragilis septicaemia, the authors review recent data from the literature related to this topic. they first note the increasing prevalence, accounting for approximately 10 per cent of all septicaemias at the present time. they note that the most frequent portals of entry are sites of localised suppuration, related on the one hand to digestive or gynaecological surgery and, secondly, to the post-partum or post-abortum period. from a therapeutic standpoint ...	1977	23026
the hydrolysis of dextran by gram negative non-sporing anaerobic bacilli.		1977	24035
quantitative evaluation of three commercial blood culture media for growth of anaerobic organisms.	the ability of three different commercial blood culture media--brain heart infusion broth (pfizer), thiol broth (difco), and prs-peptone broth (becton, dickinson & co.)--to support the growth of five different anaerobes is described. inocula of 100 and 1,000 colony-forming units per ml were used to evaluate potential differences in survival, lag time, growth rate, and doubling times of each anaerobe in each medium. in addition, each medium was evaluated for its ability to neutralize the antibact ...	1978	24059
formation of glycosidases in batch and continuous culture of bacteroides fragilis.	nine strains of bacteroides fragilis were cultivated in stirred fermentors and tested for their ability to produce glycosidases. b. fragilis subsp. vulgatus b70 was used for optimizing the production of glycosidases. the highest bacterial yield was obtained in proteose peptone-yeast extract medium. the optimum ph for maximal bacterial yield was 7.0, and the optimum temperature for growth was 37 degrees c. the formation of glycosidases was optimal between ph 6.5 and 7.5, and the optimum temperatu ...	1978	25044
the bactericidal activity of nitrofurantoin and metronidazole against anaerobic bacteria.		1978	25874
characterization of receptors mediating 5-hydroxytryptamine- and catecholamine-induced platelet aggregation, assessed by the actions of alpha- and beta-blockers, butyrophenones, 5-ht antagonists and chlorpromazine.	1 blood platelets from normal human volunteers were isolated and aggregated in vitro with 5-hydroxytryptamine (5-ht), noradrenaline (na), dopamine and n-dimethyldopamine (dmda). 2 the effects of 5-ht antagonists, alpha- and beta-adrenoceptor blocking agents, butyrophenones and chlorpromazine upon aggregation induced by the four amines were investigated. 3 only the the 5-ht antagonists, chlorpromazine and spiroperidol were potent inhibitors of 5-ht-induced aggregation, and only phentolamine was a ...	1978	26445
beta-lactamases in bacteroides.	bacteroides fragilis is responsible for most anaerobic infections in man. most isolates of b. fragilis show resistance to beta-lactam antibiotics. this resistance might be due to beta-lactamase production or permeability barrier in the cell wall. b. fragilis produce beta-lactamase with mainly cephalosporinase activity. other bacteroides species such as b. clostridiformis, b. melaninogenicus and b. oralis also produce beta-lactamase but with different biochemical characteristics.	1978	28561
chloramphenicol acetyltransferase of bacteroides fragilis.	chloramphenicol-resistant strains of bacteroides fragilis (minimum inhibitory concentration, 12.5 mug/ml) were isolated from a stool specimen which contained multiply resistant escherichia coli. the enzyme responsible for resistance, chloramphenicol acetyltransferase, was produced constitutively by these strains; the specific activity was 10-fold lower than that of the e. coli enzymes. similar activity was not detected in susceptible b. fragilis strains, nor could it be induced by growth in the ...	1978	28690
cefoxitin sodium activity against anaerobes: effect of the inoculum size, ph variation and different culture media.		1978	29027
pleuropulmonary lung infection by anaerobic bacteria.	two patients with severe pleuropulmonary infection caused by non-sporing anaerobic bacteria are described. one had an empyema with foul-smelling pus and developed bacteraemia, and the other developed a lung abscess. both were successfully treated with antibiotics and drainage, chest surgery being avoided. the successful diagnosis and treatment of these patients involved close liaison between clinical and laboratory staff.	1978	29654
metronidazole in the prophylaxis and treatment of anaerobic infection.	the influence of prophylactic metronidazole on vaginal carriage rates of anaerobes and the development of postoperative anaerobic infection was studied in 104 women who underwent abdominal hysterectomy. metronidazole prophylaxis in 54 patients led to a decrease in the anaerobe vaginal carriage rate from 65% pre-operatively to 17% and 28% on the 3rd and 7th postoperative days respectively. in the control group (50 patients) no significant decrease in anaerobe yield was noted, corresponding percen ...	1978	33454
chromogenic cephalosporin spot test to detect beta-lactamase in clinically significant bacteria.	lactamase production. reacteroides melaniongenicus, 14	1979	34624
[bacteriological studies of peritonitis].	bacterial infections of the peritoneum may be primary (pneumococcal peritonitis of childhood). these are rare, as are streptococcal and staphylococcal peritonitis in the neonate, following umbilical or tegumental infections. the great majority of cases of peritonitis are secondary to an adjacent inflammation, a perforation of the gastro-intestinal tract, or trauma, which may be surgical in origin. the microbial flora involved is generally mixed, with a high proportion of anaerobic organisms, ref ...	1978	35067
[antibiotic treatment in acute peritonitis].	the selection depends on several factors and in particular: -the means of transport by which the antibiotic reaches the peritoneum : the aminosides and the betalactamines attain the peritoneum easily while the polymyxins do not; -the causative agent: most often it is a gram negative aerobic or anaerobic bacteria. the entero-bacteria predominate but in the last few years bacteroides fragilis has been frequently encountered giving rise to numerous studies. the flora is most often polymicrobic. th ...	1978	35071
autologous transfusion in obstetrics and gynecology.	two cases are presented which illustrate the use of autologous blood transfusion for elective surgery in obstetrics and gynecology. the advantages and disadvantages are described and review of the pertinent literature over the past century is summarized.	2001	35402
intracellular polysaccharide of bacteroides fragilis.	formation of iodophilic polysaccharide (ips) from glucose was demonstrated in 27 strains of bacteroides fragilis. synthesis was dependent on the glucose concentration of the medium, the ph and the growth phase. when glucose was in short supply the cellular polysaccharide was degraded rapidly at ph 4.5 to 6.5 and fatty acids accumulated in the medium. storage of ips was not responsible for the low carbon recoveries observed in fermentation balance studies. in electron micrographs of thin sections ...	1979	37285
antibiotic susceptibility of anaerobic bacteria with special reference to bacteroides fragilis.	it was shown that recent swedish clinical isolates of anaerobic bacteria are susceptible to many antibiotics by the agar dilution method with the exception of the bacteroides group versus beta-lactam antibiotics or tetracyclines. strains of b. fragilis were inhibited by 4--greater than 128 micrograms benzylpenicillin or cephalothin/ml, 1.0--64 micrograms cefoxitin/ml, 0.064--2 micrograms clindamycin or metronidazole/ml, 2--8 micrograms chloramphenicol/ml, 2--16 micrograms fusidic acid/ml and 0.0 ...	1979	37593
[anaerobic gram negative septicemias in digestive tract surgery and in surgical intensive care].		1979	39472
characterization of anaerobic gram-negative bacilli by using rapid slide tests for beta-lactamase production.	a total of 175 isolates of anaerobic gram-negative bacilli were tested for beta-lactamase production by using a slide test modification of the chromogenic cephalosporin (nitrocefin, glaxo, middlesex, england) assay and the iodometric slide test. included isolates were bacteroides melaninogenicus (46), b. fragilis (78), other bacteroides isolates (21), fusobacterium (25), and other gram-negative bacilli (5). both slide tests detected 25 b. melaninogenicus isolates that were beta-lactamase produce ...	1979	41001
anaerobic isolates in chronic recurrent suppurative otitis media. treatment with carbenicillin alone and in combination with gentamicin.	tympanocentesis was performed in 32 pediatric patients with chronic recurrent suppurative otitis media. the aspirate was cultured aerobically and anaerobically. aerobes were isolated from ten patients (31.2%); anaerobes from one patient; and both aerobes and anaerobes from 21 patients (65.6%). there were 46 aerobic isolates. the aerobes commonly recovered were pseudomonas aeruginosa (24 isolates) proteus sp. (5) and staphylococcus aureus (3). there were 32 anaerobes isolated including anaerobic ...	1979	41811
fluorescent antibody test kit for rapid detection and identification of members of the bacteroides fragilis and bacteroides melaninogenicus groups in clinical specimens.	the fluoretec fluorescent antibody test kit (pfizer inc., new york, n.y.), developed for the rapid detection of members of the bacteroides fragilis and b. melaninogenicus groups, was evaluated by testing 58 stock cultures and 76 clinical specimens. the test reagents detected 100% of 40 b. fragilis and b. thetaiotaomicron stock culture strains, although only 22% of 18 b. vulgatus, b. distasonis, and b. ovatus strains showed positive fluorescence. the 76 clinical specimens were evaluated by examin ...	1979	41847
rapid diagnosis of anaerobic infections by gas-liquid chromatography.	it was postulated that the short chain fatty acids (scfa) produced by anaerobic bacteria might serve as microbial markers in purulent material. eighteen pus specimens from various sources were analysed by gas-liquid chromatography (glc), and the scfa detected were compared with the microorganisms isolated by conventional methods. it was found that the detection of propionic, isobutyric, butyric, or isovaleric acids by direct glc of pus specimens is strong evidence for anaerobic infection but not ...	1979	41850
virulence factors of anaerobic bacteria: summary of the symposium.		1979	44924
purification and properties of beta-lactamase from bacteroides fragilis.	beta-lactamase activity was detected either biologically or using the chromogenic cephalosporin 87/312 in 20 clinical isolates of bacteroides fragilis with penicillin g minimal inhibitory concentrations of 10 to 100 micrograms/ml. strain am78 (minimal inhibitory concentration, greater than 1,000 micrograms/ml) was used to optimize the conditions for production, assay, and storage of the enzyme. the enzymes are cell associated, with less than 1% of activity being found in culture fluids during gr ...	1978	45494
genetic determinants of microbial resistance to antibiotics.	emergence of antibiotic resistance is related to the ease of mutation, to the extent of exchange of genetic information in bacteria by conjugation, transformation, and transduction, and to the large-scale use of antimicrobial agents in the biosphere. in addition to the development of resistance through chromosomal mutation and exchange of chromosomal genes among organisms, there is a more profound enlargement of the gene pool by the dissemination and amplification of plasmids. two examples of th ...	1979	45522
letter: tk-polyagglutination in bacteroides fragilis septicaemia.		1975	46439
o-antigenic specificity of lipopolysaccharides from bacteroides fragilis ss. fragilis.	lipopolysaccharides (lps) isolated from three strains of bacteroides fragilis ss. fragilis were examined by indirect haemagglutination and inhibition of haemagglutination in unabsorbed and absorbed rabbit antisera. six different antigenic specificities were detected. all serological activity was destroyed by oxidation of lps with periodate.	1975	52280
effect of bacteroides fragilis on the human erythrocyte membrane: pathogenesis of tk polyagglutination.	incubation of normal human erythrocytes with the supernatant of centrifuged culture of some strains of bacteroides fragilis results in the exposure of tk polyagglutination determinants on the erythrocyte membrane. these determinants are present on non papain-labile structures and are probably exposed by an enzyme mechanism. other strains of b. fragilis were found to produce neuraminidase, haemolysins, and protease. it is suggested that early recognition of tk determinants may be an aid to the di ...	1975	54368
biological effects of carbon monoxide vs. whole emissions from engine with catalyst.		1976	55426
letter: daunorubicin cardiotoxicity.		2001	55702
bacteroides: an unusual cause of breast abscess.	three cases of breast abscess from which the non-sporing anaerobe bacteroides was isolated are described. this organism has apparently not previously been reported as a cause of abscess in a breast without underlying malignancy.	1976	59152
[arthritis related to intestinal anastomoses].	jejuno-colic and jejuno-ileal anastomoses may provoke arthritis. the recently recognized physiopathology is that of arthritis due to immune complexes related to pullulation of escherichia coli and of bacilus fragilis. these cases of arthritis, usually sensitive to therapy, have, in some stutborn cases, required the re-establishment of intestinal continuity, which in each case has made the joint phenomena disappear.	1976	62379
a gram stain for smears of blood cultures, body fluids and tissues.	a new gram stain method for blood cultures was adapted from a method for tissue sections. this was accomplished by comparing various modifications of the latter method on positive smears prepared from a 24-hour negative blood culture seeded with staphylococcus aureus and escherichia coli. a blind study was then conducted using the new method and hucker's method on 24-hour and 72-hour blood cultures as well as a limited number of other body fluids and tissues. of the 35 positive blood cultures de ...	1976	62513
antibody clearance by micropinocytosis: a possible role in fetal immunoprotection.		2001	64836
the immunochemical investigations of six bacteroides serotypes.		1976	65113
cross-reactivity of bacteroides fragilis o antigens.	the cross-reactivity of o antigens prepared from bacteroides fragilis, other bacteroides species and from fusobacterium has been examined by indirect haemagglutination and inhibition of haemagglutination. fifteen of 20 b. fragilis ss. fragilis strains showed o-antigenic cross-reactivity with one or more of the test strains of b. fragilis ss. fragilis: nctc 9343, lille e 323 and sbl b55. the same applies also to 3 strains classified as b. coagulans, b. hypermegas and b. putredinis. the multispeci ...	1977	65902
identification of the presence and type of biliary microflora by immediate gram stains.	immediate gram stains were performed on gallbladder bile aspirated at the start of an operation for biliary disease in 191 consecutive patients undergoing elective biliary surgery. the results of the gram stains were telephoned to the operating theater within 20 minutes of collection. the over-all accuracy rate of the telephone gram stain reports compared with the subsequent bile cultures was 77 percent. the incidence of false-positive results was 12 percent, and false-negative results were reco ...	1977	66763
bacteroides fragilis meningitis.		1977	69093
prophylactic systemic antibiotics in colorectal surgery.	the prophylactic value of gentamicin combined with either lincomycin or metronidazole in 52 patients undergoing colorectal surgery was investigated. the results confirmed the value of this practice. in a control group, the sepsis-rate was 48% with 1 death attributable to sepsis, compared with a sepsis-rate of 4% in the treated group. the combination of gentamicin and lincomycin was effective against sepsis but pseudomembranous colitis developed in 2 of the 14 patients treated with this combinati ...	1977	69126
clavulanic acid and susceptibility of bacteroides fragilis to penicillin.		1977	69229
fluorescent-antibody studies on selected strains of bacteroides fragilis subspecies fragilis.	antisera against seven strains of bacteroides fragilis subspecies fragilis were produced from dense suspensions of whole cells. these sera exhibited high agglutination titers with homologous antigens. reciprocal cross-reactions in agglutination tests with each immunizing strain yielded lower titers. both the indirect and direct fluorescent-antibody techniques were used to evaluate these reagents in the serological identification of 24 defined strains of b. fragilis subspecies fragilis. subspecie ...	1977	72076
inhibition of phagocytosis in vitro by obligate anaerobes.	a variety of species of obligate anaerobes have been shown to interfere with the phagocytosis and killing of proteus mirabilis and other aerobic bacteria in vitro. although all the obligate anaerobes examined showed this activity, the effect was greatest with strains of bacteroides melaninogenicus and b. fragilis. in contrast, none of the 36 aerobes tested acted in this way. these observations suggest that the presence of obligate anaerobes may be fundamental to the pathogenesis of some types of ...	1977	73952
bacteroides fragilis resistant to metronidazole after long-term therapy.		1978	74641
metronidazole resistance among bacteroides fragilis.		1978	76262
pseudomembranous colitis.		1978	77373
chemotherapy of brain abscess.		1978	82092
bowel preparation for surgery.		1978	82688
a case of atypical polyagglutinability due to tk-transformation.	a case of acquired transient polyagglutinability in a group o, rh(d) positive female patient, wa, is described. an unusual finding in the preliminary serological investigation was the non-reaction of the cells with peanut (arachis hypogaea) extract. the patient's red cells were strongly agglutinated by normal human and rabbit sera from which anti-t had been removed. electrophoretic mobility studies and tests with polybrene indicated that their sialic acid content was normal. the use of a specifi ...	1978	83151
anaerobic subareolar breast abscess.	15 non-puerperal women with breast abscess were seen during one year. in 8, anaerobes were cultured from pus obtained from the abscess, in 6, staphylococcus aureus was grown, and in 1 the pus was sterile on culture. all 7 breast abscesses in puerperal women seen during the same period were staphylococcal. the anaerobic abscesses were all subareolar; they were recurrent in 4 patients and were associated with retracted nipples in 7. the anaerobes isolated were those found as normal commensals in t ...	1979	83476
bacteroides species in subareolar breast abscess.		1979	84281
[surgical palliative procedures in patients with carcinoma of the biliary tract (author's transl)].	a report is given of 72 patients suffering from carcinoma of the extrahepatic biliary ducts. carcinoma of the gallbladder usually grow fast invading the surrounding tissue. thus cholecystectomy can be performed only as a pallouative procedure in most cases, and partial resection of the liver does not yield better results in general. carcinoma of the ductus hepaticus usually grows slowly and metastases are formed lately in the course; thus patients usually die due to occlusion of the ducts and ja ...	1999	84316
diisopropylfluorophosphate-evoked inhibition of anaphylactic histamine release from human skin: decrease of the inhibition by storing the skin specimens.	antigen-induced histamine release from human skin slices passively sensitized with reaginic serum in vitro was inhibited by dfp, suggesting involvement of serine esterase activation in the reaction. the magnitude of dfp-evoked inhibition of the histamine release was not the same in each skin sample and no correlationship was observed between the magnitude of the dfp-evoked inhibition of the histamine release and that of the histamine release in the absence of dfp. the magnitude of the histamine ...	1979	84487
the hair in acrodermatitis interopathica--a disease indicator?		1999	84500
[the adrenaline-sensitive adenylate cyclase system (proceedings)].		1999	84562
study of the glycolipid composition of the milk fat-globule membrane and the mouse mammary tumour virus prepared from the milk of infected swiss mice [proceedings].		1978	84579
localization of nors in chromosomes of mouse cell lines by a combined 33258-hoechst and ag-staining technique.		1979	84805
rapid diagnosis of bacteroides infections by indirect immunofluorescence assay of clinical specimens.	43 specimens from a variety of sites were directly examined by indirect immunofluorescence assay (i.f.a.) with specific antisera against the capsular polysaccharide of bacteroides fragilis and pooled antisera against a number of serotypes of bacteroides sp. (all of the former b. fragilis subspecies). the findings were compared with those of routine anaerobic bacteriology and gas liquid chromatography for short chain fatty acids. examination by i.f.a. was a sensitive (100%) and specific (90.3%) m ...	1979	84899
a.f.p. and congenital nephrosis finnish type.		1999	84930
administration of teaching hospitals.		1999	84961
twice-weekly regimen for replacement therapy in uncooperative patient with hypopituitarism.		1999	84966
sensitivity to enkephalin as a cause of non-insulin dependent diabetes.	non-insulin-dependent diabetes is associated with facial flushing after alcohol in patients on chlorpropamide (chlorpropamide alcohol flushing, c.p.a.f.) especially when there is a family history of diabetes. c.p.a.f. in three subjects (two diabetics, one non-diabetic) was blocked by the specific opiate antagonist naloxone. in nine subjects (six diabetics) c.p.a.f. was reproduced by the enkephalin analogue with opiate-like activity [d-ala2, mephe4, met (o)-ol] enkephalin (damme). c.p.a.f. thus m ...	1999	84999
highly purified insulins.		1979	85008
whipple's disease: a multisystem infection.		1999	85261
effect of light on the labeling of optic tectum gangliosides after an intraocular injection of n-[3h]acetylmannosamine.		1999	85450
relationship of intracellular 3',5'-adenosine monophosphate accumulation to parathyroid hormone release from dispersed bovine parathyroid cells.		1978	85548
[method of preparing the tularemia antigen for an erythrocyte diagnosticum].		1979	85742
[industrial output of a hemiglobincyanide reference standard].		1999	85761
copper, superoxide radical, diethyldithiocarbamate, and bleomycin cytotoxicity.		2000	86012
plasma perfusion in treatment of cold rash and systemic lupus erythematosus.		2000	86013
metronidazole-resistant bacteroides from untreated patient.		1979	86085
x-linked immunocompetence and epstein-barr virus oncogenesis.		1979	86133
antitumour effect of cimetidine.		2000	86136
[perichordal necroses. contribution to the understanding of the spinal column morphogenesis].	in 12--15 days old rat embryos and 12 days old mouse embryos vitally stained by acridin orange, a perichordal necrosis appears, showing metameric intensifications at the level of the dense sclerotomites. similar aspects were detected in serially sectioned rabbit and human embryos (6--7 mm c.r. length). the authors correlate the necrotic zones mentioned with the inductive functions of the notochord.	1978	86154
chemical and serological comparison of two antigen extracts of thermoactinomyces candidus.		1979	86157
effect of hypoxia on the capillarity of guinea pig skeletal muscle.		1979	86189
allo-anti-c in a patient who had previously made an autoantibody mimicking anti-c.	a patient, previously studied by us, who had produced a benign autoantibody with a specificity that mimicked anti-c, has now produced allo-anti-c that is not of the mimicking type. she is no longer producing any serologically demonstrable autoantibody. it is highly probable that conversion from auto to alloantibody production in this patient was prompted by the introduction of additional foreign immunogen on fetal red blood cells during her third pregnancy.	2000	86216
[intratypical antigenic differentiation of poliovirus strains circulating in mali by means of cross-adsorbed sera].	the intratypic antigenic differentiation of poliovirus strains isolated from sick or healthy children in mali in 1975-1976 was performed. the method is based on the use of cross-adsorbed sera in the neutralization tests in which the virus is titrated by the plaque procedure or by the cytopathic effect. all the examined strains of serologic types i, ii, and iii were distinguished by the antigenic structure from the vaccine strains and were classified as "wild". quantitative differences in the ant ...	1978	86237
the use of trypan blue for counterstaining in the sepharose bead immunofluorescence test. the application of the test for the demonstration of primate retrovirus-specific antibodies and antigens.	the sepharose bead immunoflurorescence test was performed by counterstaining the beads with trypan blue. this results in a red staining of negative beads which allows an easy distinction from positive green-fluorescent beads. sepharose beads conjugated with viral proteins or antiviral antibodies were used to demonstrate mason-pfizer monkey virus (mpmw)- and simian sarcoma virus (ssv) - specific antigens or antibodies. the test shows a high sensitivity and specificity and needs a small amount of ...	1978	86253
tissue cea in premalignant epithelial lesions and epidermoid carcinoma of the uterine cervix: prognostic significance.	carcinoembryonic antigen (cea) was studied by the indirect triple-bridge immunoperoxidase method in formalin-fixed paraffin-embedded tissue specimens from 191 patients with premalignant epithelial lesions or epidermoid carcinoma of the uterine cervix treated 12 years ago. the frequency of tissue cea positivity was found to increase with advancing clinical disease in the following manner: mild dysplasia, 25%; severe dysplasia, 37%; carcinoma in situ, 60%; invasive carcinoma stage i, 60%; stage ii ...	2000	86522
ultrastructure of bacteroides species: bacteroides asaccharolyticus, bacteroides fragilis, bacteroides melaninogenicus subspecies melaninogenicus, and b. melaninogenicus subspecies intermedius.	representative strains of two subspecies of bacteroides melaninogenicus (subspecies melaninogenicus and subspecies intermedius) and bacteroides asaccharolyticus as well as b. asaccharolyticus strain 536b isolated from a human perirectal abscess and bacteroides fragilis atcc 25285 were examined by glutaraldehyde-osmium fixation, ruthenium red fixation and staining, and thorium hydroxyde staining as well as by the physical preparative techniques of critical point drying--transmission electron micr ...	1979	86590
the results of prostatectomy: a symptomatic and urodynamic analysis of 152 patients.	there were 152 patients with prostatism investigated by inflow cystometry and pressure flow analysis of micturition before and after elective prostatectomy. many symptoms attributed to obstruction were found to be owing to bladder instability, which was demonstrated in 60 per cent of the patients. the symptomatic improvement postoperatively was accompanied by a decrease in the incidence of instability to 25 per cent. the repeat urodynamic studies and symptom analysis demonstrated a surgical succ ...	2000	86617
[determination of blood loss by protein-, erythrocyt- and hemoglobinuria indices].		2000	86649
[toxicity, pharmacokinetics and pharmacodynamics of the soviet bleomycin, bleomycetin, in a single administration to laboratory animals].	toxicity of bleomycetin (bleomycin a2) administered intravenously, intraperitoneally, subcutaneously or intramusculary in a single dose to animals was almost identical. on its oral administration bleomycetin was 10--14 times less toxic than on its parenteral use. rats were somewhat less sensitive to bleomycetin than mice. bleomycetin had no significant effect on the level of the arterial pressure, respiration, ecg characteristics and elements of the vegetative nervous system in narcotized cats. ...	1979	87149
chronotropic response of isolated atria to acid base alterations.	the effect of acid-base alterations on spontaneous rate was analysed using isolated atria exposed to cumulative degrees of acidosis produced either by adding hcl or by increasing pco2 in the incubation medium. frequncy vs. ph curves were made to assess chronotropic response to acid-base changes. heart rate was increased in alkalosis and decreased when the ph of the medium was lowered. both "respiratory" and "metabolic" alterations affected the contraction rate to the same extent. decreasing ph f ...	1978	87182
benign prostatic hypertrophy: when should you consider prostatectomy for your patient?	watching the way a patient voids is the easiest way to determine the presence of prostatic obstruction. uroflowmetry can objectively measure the amount of obstruction. clinical evaluation of prostatism should include an intravenous urogram, serum creatinine determination, urinalysis, urine culture, and cystoscopy. suspicious areas of induration in the prostate should be biopsied. surgery is not required for most men with prostatic hypertrophy. indications for prostatectomy are severe symptoms of ...	2000	87358
similarity of casein- and endotoxin-induced, myeloma- associated and aged sjl/j amyloid in various strains of mice.	amyloidosis was induced in a number of strains of mice by repeated injections of casein and endotoxin. spontaneous amyloid was obtained from balb/c mice bearing a myeloma tumor (igg2a producing mopc 173 tumor) and from aged sjl/j mice. both the induced and spontaneous forms were similar in their size, immunological reactivity, peptide maps and in the susceptibility of histological sections to oxidizing agents with or without trypsin digestion. since case-induced murine amyloid resembles the noni ...	1979	87374