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wu polyomavirus in children with acute lower respiratory tract infections, south korea.in south korea, wu polyomavirus (wupyv) was detected in 34 (7%) of 486 children with acute lower respiratory tract infections, 3 (4.2%) of 72 asymptomatic children, and as coinfection with other respiratory viruses in 23 (67.6%) children. although wupyv was frequently detected, its clinical role has not been distinguished from that of coinfecting viruses.200718217567
[discovery and identification of wu polyomavirus in children from zhejing region].wu polyomavirus, which was firstly discovered in 2007, is a new human polyomavirus belonging to polyomaviridae and containing circular double-stranded genomic dna. in this study, the 278 clinical sputum specimens from children under 5 years old were collected from wenzhou medical college affiliated wenling first hospital, zhejiang province. based on identification assay of wu polyomavirus previously reported, a wu polyomavirus was identified from clinical samples successfully, the positive rate ...200818320826
wu polyomavirus in children, canada.wu polyomavirus was detected in nasopharyngeal aspirates in 2 (2.5%) of 79 children with respiratory infections (both infected with respiratory syncytial virus) and in 5 (6.4%) of 78 asymptomatic children during the same winter season in canada. the strains were closely related to australian and american viruses based on analysis of large t antigen (tag) and vp2 genes. the pathogenic role of wu virus is still uncertain.200718258053
clinical and epidemiologic characterization of wu polyomavirus infection, st. louis, missouri.wu polyomavirus is a recently described polyomavirus found in patients with respiratory infections. of 2,637 respiratory samples tested in st. louis, missouri, 2.7% were positive for wu polyomavirus by pcr, and 71% were coinfected with other respiratory viruses. persistent human infection with wu polyomavirus is described.200718258052
wu polyomavirus in children with acute lower respiratory tract infections, china.wu polyomavirus (wupyv), a new member of the genus of polyomavirus in the family polyomaviridae, has been found and associated with respiratory tract infections recently. however, its clinical role and pathogenicity has not been known.200818242126
dna from bk virus and jc virus and from ki, wu, and mc polyomaviruses as well as from simian virus 40 is not detected in non-uv-light-associated primary malignant melanomas of mucous membranes.the single most important causative factor for malignant melanomas of the skin is uv radiation. however, this is not true for melanomas on body surfaces sheltered from the sun; thus, it is important to seek new causative factors of melanoma genesis. human papillomaviruses and gammaherpesviruses are associated with human skin cancer; for example, human papillomavirus types 5 and 8 are associated with epidermodysplasia verruciformis, and human herpesvirus 8 is associated with kaposi's sarcoma. rec ...200818768658
wu polyomavirus infection in children, germany. 200818394299
[wu polyomavirus and ki polyomavirus detected in specimens from children with acute respiratory tract infection in china].to investigate newly identified polyomavirus wuv and wuv and kipyv are associated with acute respiratory infections in china, tests were developed to detect wuv and kipyv gene fragments from nasopharyngeal aspirates collected from children with ari fron nov. 2006 to oct. 2007.200818414691
age-related pattern of ki and wu polyomavirus infection.the role of two recently identified polyomaviruses, ki and wu, in the causation of respiratory disease has not been established.200818573691
detection of wu polyomavirus dna by real-time pcr in nasopharyngeal aspirates, serum, and stool samples.the human wu polyomavirus (wupyv) has been recently described as a novel virus in respiratory tract samples.200919157970
wu polyomavirus in patients infected with hiv or hepatitis c virus, connecticut, usa, 2007.wu polyomavirus (wupyv) was detected in 10 (8.3%) of 121 hiv-positive plasma specimens, 0 (0%) of 120 hiv-negative serum specimens, and 2 (2.5%) of 79 hepatitis c virus (hcv)-positive serum specimens. ki polyomavirus was not detected in hiv-positive plasma or hcv-positive serum specimens. hiv-infected persons may be susceptible to systemic wupyv infection.200919624928
wu polyomavirus in fecal specimens of children with acute gastroenteritis, china. 200919116080
detection of wu polyomavirus in cerebrospinal fluid specimen from a patient with aids and suspected progressive multifocal leukoencephalopathy. 200919530941
human ki and wu polyomavirus infection in immunocompromised subjects. 200919560964
no evidence for wu polyomavirus infection in chronic obstructive pulmonary disease.human polyomaviruses are known to cause persistent or latent infections, which are reactivated under immunosuppression. polyomaviruses have been found to immortalize cell lines and to possess oncogenic properties. moreover, the recently discovered merkel cell polyomavirus shows a strong association with human merkel cell carcinomas. another novel human polyomavirus, wu polyomavirus (wupyv), has been identified in respiratory specimens from patients with acute respiratory tract infections (arti). ...200919715607
serologic evidence of frequent human infection with wu and ki polyomaviruses.wu polyomavirus (wupyv) and ki polyomavirus (kipyv) are novel human polyomaviruses. they were originally identified in human respiratory secretions, but the extent of human infection caused by these viruses has not been described to date. to determine the seroepidemiology of wupyv and kipyiv, we used an elisa to screen serum samples from 419 patients at the st. louis children's hospital and barnes-jewish hospital during 2007-2008. the age-stratified deidentified samples were examined for antibod ...200919751580
association of merkel cell polyomavirus-specific antibodies with merkel cell carcinoma.merkel cell polyomavirus (mcpyv) has been detected in approximately 75% of patients with the rare skin cancer merkel cell carcinoma. we investigated the prevalence of antibodies against mcpyv in the general population and the association between these antibodies and merkel cell carcinoma.200919776382
identification of wu polyomavirus from pediatric patients with acute respiratory infections in beijing, china.a novel polyomavirus (wu virus) has been identified in pediatric patients with acute respiratory tract infections (ari), but its role as a respiratory pathogen has not yet been demonstrated. to investigate if wu virus is related to acute respiratory infections in infants and children in beijing, specimens collected from 674 pediatric patients with ari from april 2007 to may 2008 and from 202 children without ari were used for this investigation. common respiratory viruses were tested by virus is ...201019946716
ki polyomavirus detected in respiratory tract specimens from patients in st. louis, missouri.studies have reported the presence of ki polyomavirus (kipyv) and wu polyomavirus (wupyv) in respiratory secretions of young patients. so far, evidence has not supported a link between infections with either virus and respiratory tract disease; however, there has not been a large comparison of kipyv-infected patients to age-matched patient groups.201019949359
whole-genome characterization and genotyping of global wu polyomavirus strains.exploration of the genetic diversity of wu polyomavirus (wuv) has been limited in terms of the specimen numbers and particularly the sizes of the genomic fragments analyzed. using whole-genome sequencing of 48 wuv strains collected in four continents over a 5-year period and 16 publicly available whole-genome sequences, we identified three main wuv clades and five subtypes, provisionally termed ia, ib, ic, ii, iiia, and iiib. overall nucleotide variation was low (0 to 1.2%). the discriminatory p ...201020357093
[detection and clinical characterization of wu polyomavirus in acute respiratory tract infection in children].wu polyomavirus (wupyv), a new member of the genus polyomavirus in the family polyomaviridae, has been found to be associated with respiratory tract infections recently. but the role of the wupyv as agents of human disease remains uncertain. we sought to describe the detection and clinical characterization of wupyv in acute respiratory tract infection in children.201020426930
ki and wu polyomaviruses and cd4+ cell counts in hiv-1-infected patients, italy.to investigate an association between ki and wu polyomavirus (kipyv and wupyv) infections and cd4+ cell counts, we tested hiv-1-positive patients and blood donors. no association was found between cell counts and virus infections in hiv-1-positive patients. frequency of kipyv infection was similar for both groups. wupyv was more frequent in hiv-1-positive patients.201020735940
[progress in studies on human wu polyomavirus]. 201021055301
[genomic characterization of wu polyomavirus identified from pediatric patients with acute respiratory infections in beijing, china].to characterize the genomic sequence and arrangement of wu polyomavirus (wu virus) identified in clinical specimens collected from children with acute respiratory infections in beijing, china, the sequences of capsid proteins vp1, vp2, and the large tumor antigen (ltag), as well as the 5'-terminal sequence of wu virus, were amplified from the clinical specimen with id number of bjf5276 which was determined as wu virus positive by pcr amplification. the pcr amplicons were sequenced, and genomic s ...201021344748
[sequencing and analysis of the complete genome sequence of wu polyomavirus in fuzhou, china].wu polyomavirus (wupyv), a new member of the genus polyomavirus in the family polyomaviridae, is recently found in patients with respiratory tract infections. in our study, the complete genome of the two wupyv isolates (fz18, fztf) were sequenced and deposited in genbank (accession nos. fj890981, fj890982). the two sequences of the wupyv isolates in this study varied little from each other. compared with other complete genome sequences of wupyv in genbank (strain b0, s1-s4, clff, accession nos. ...201121528542
detection of ki polyomavirus and wu polyomavirus dna by real-time pcr in nasopharyngeal swabs and in normal lung and lung adenocarcinoma tissues.polyomaviruses ki (kipyv) and wu (wupyv) were detected from 7 (3.0%) and 38 (16.4%) of 232 children with respiratory tract infections by real-time pcr. the rates of single infection of kipyv and wupyv were 3 (42.9%) of 7 and 20 (52.6%) of 38, respectively. in other samples, various viruses (human respiratory syncytial virus, human metapneumovirus (hmpv), human rhinovirus, parainfluenza virus 1 and human bocavirus) were detected simultaneously. one case was positive for kipyv and wupyv and also f ...201121545509
wu polyomavirus infection among children in south china.this study aimed at investigating the prevalence and clinical characteristics of children with respiratory infection by wu polyomavirus (wupyv) in southern china. nasopharyngeal aspirate samples were collected from 771 children with acute respiratory tract infection admitted to hospital and 82 samples from healthy subjects for routine examination at the outpatient service at the second affiliated hospital of shantou university, medical college from july 2008 to june 2009. wupyv was detected by t ...201121678448
secondary lymphoid tissue as an important site for wu polyomavirus infection in immunocompetent children.the polyomaviruses ki and wu (kipyv and wupyv) have been identified in respiratory specimens from children with acute respiratory infections, which suggests the respiratory tract as a possible site of infection. however, the persistence of infection in the lymphoid system is unknown. fresh samples (n = 211) of tonsils, adenoids, and peripheral blood mononuclear cells (pbmcs) from 83 immunocompetent children (mean age 4.8 years) were tested for amplification of the kipyv vp1 and wupyv vp2 genes. ...201121678449
Seroepidemiology of WU polyomavirus among children exposed perinatally to HIV-1.WU polyomavirus (WUPyV), a new member of the genus wukipolyomavirus in the family Polyomaviridae, has been detected in serum and tissues of individuals infected with HIV. However, the epidemiology of WUPyV among children exposed perinatally to HIV-1 is unknown. To investigate the epidemiology of WUPyV in children exposed to and infected perinatally with HIV, serum samples from 150 children exposed to HIV and 114 children infected with HIV were screened for IgG antibodies to WUPyV. A subset was s ...201222170536
wu polyomavirus infection confirmed by genetic and serologic tests in an infant with bronchitis. 201121915023
wu polyomavirus (wupyv): a recently detected virus causing respiratory disease?the wu polyomavirus (wupyv) is a novel member of the family polyomaviridae recently detected in respiratory tract specimens by shotgun sequencing. intriguingly, viral genome has been detected in 0.4% to 11.5% of respiratory tract specimens from children with respiratory disease. the levels of co-infection with established respiratory viruses were in the range between 30.8% and 91.7%. moreover, some studies report detection of wupyv in stool or serum. so far, wupyv infections can not be distingui ...200921994565
a naturally transmitted epitheliotropic polyomavirus pathogenic in immunodeficient rats: characterization, transmission, and preliminary epidemiologic studies.we report the identification, pathogenesis, and transmission of a novel polyomavirus in severe combined immunodeficient f344 rats with null prkdc and interleukin 2 receptor gamma genes. infected rats experienced weight loss, decreased fecundity, and mortality. large basophilic intranuclear inclusions were observed in epithelium of the respiratory tract, salivary and lacrimal glands, uterus, and prostate gland. unbiased viral metagenomic sequencing of lesioned tissues identified a novel polyomavi ...201728782456
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