use of linezolid to treat mrsp bacteremia and discospondylitis in a dog. | a 1.5 yr old male german shepherd dog was evaluated for recurrent intermittent episodes of fever and lethargy. clinicopathologic abnormalities were suggestive of a discospondylitis at the seventh and eighth thoracic vertebrae. blood and urine cultures yielded growth of methicillin-resistant staphylococcus pseudintermedius (mrsp) that was resistant to all commonly used antibiotics. extralabel antibiotic susceptibility testing demonstrated susceptibility of both blood and urine isolates to linezol ... | 2015 | 24216492 |
adverse effects of rifampicin in dogs and serum alanine aminotransferase monitoring recommendations based on a retrospective study of 344 dogs. | rifampicin has been reported to have potent activity against staphylococci, including meticillin-resistant staphylococcus pseudintermedius. there is limited documented information regarding adverse effects and recommendations for serum biochemistry monitoring. | 2013 | 24164464 |
an in vitro study to determine the minimal bactericidal concentration of sodium hypochlorite (bleach) required to inhibit meticillin-resistant staphylococcus pseudintermedius strains isolated from canine skin. | meticillin-resistant staphylococcus pseudintermedius (mrsp) is becoming a more common pathogen in animals treated in veterinary hospitals, raising concerns for transmission and possible contamination of the hospital itself. the identification of effective agents for the decontamination of veterinary patients and hospitals is crucial. sodium hypochlorite (6.15%) or 'bleach' is an inexpensive and frequently used decontamination agent in human and veterinary hospitals and an adjunctive treatment fo ... | 2013 | 24118401 |
incidence of inducible clindamycin resistance in staphylococcus pseudintermedius from dogs. | clindamycin is increasingly used to treat canine pyoderma. eight of 608 staphylococcus pseudintermedius isolates were positive for inducible clindamycin resistance by double-disk diffusion testing and pcr detection of ermb. staphylococcus pseudintermedius isolates that are erythromycin resistant but clindamycin susceptible by in vitro antimicrobial susceptibility testing should be tested for inducible clindamycin resistance. | 2013 | 24025915 |
a novel fexa variant from a canine staphylococcus pseudintermedius isolate that does not confer florfenicol resistance. | transposon tn558 integrated in the chromosomal radc gene was detected for the first time in staphylococus pseudintermedius. it carried a novel fexa variant (fexav) that confers only chloramphenicol resistance. the exporter fexav exhibited two amino acid substitutions, gly33ala and ala37val, both of which seem to be important for substrate recognition. site-directed mutagenesis that reverted the mutated base pairs to those present in the original fexa gene restored the chloramphenicol-plus-florfe ... | 2013 | 23979755 |
novel pseudo-staphylococcal cassette chromosome mec element (ψsccmec57395) in methicillin-resistant staphylococcus pseudintermedius cc45. | genetic characterization of methicillin-resistant staphylococcus pseudintermedius (mrsp) from thailand and israel revealed the presence of a predominant atypical clonal lineage which was not typeable by smai-pfge and sccmec typing. all the atypical isolates (n = 34) belonged to cc45 (30 st45 and 2 st179 isolates, 1 st57 isolate, and 1 st85 isolate). the isolates originated from healthy and diseased dogs and cats, as well as from the environment of one clinic. cfr9i-pulsed-field gel electrophores ... | 2013 | 23979735 |
pharmacodynamics of doxycycline and tetracycline against staphylococcus pseudintermedius: proposal of canine-specific breakpoints for doxycycline. | doxycycline is a tetracycline that has been licensed for veterinary use in some countries, but no clinical breakpoints are available for veterinary pathogens. the objectives of this study were (i) to establish breakpoints for doxycycline and (ii) to evaluate the use of tetracycline as a surrogate to predict the doxycycline susceptibility of staphylococcus pseudintermedius isolates. mics and inhibition zone diameters were determined for 168 canine s. pseudintermedius isolates according to clinica ... | 2013 | 23966509 |
in vitro adherence of staphylococcus pseudintermedius to canine corneocytes is influenced by colonization status of corneocyte donors. | the current knowledge of in vitro adherence of staphylococcus pseudintermedius to canine corneocytes is limited to comparative analyses between strains, staphylococcal species or corneocytes collected from different breeds, body sites and hosts. however, the role played by colonization status of corneocyte donors remains unknown. the aim of this study was to evaluate the adherence properties of commensal s. pseudintermedius strains to corneocytes collected from dogs with different colonization s ... | 2013 | 23834238 |
genetic relatedness, antimicrobial and biocide susceptibility comparative analysis of methicillin-resistant and -susceptible staphylococcus pseudintermedius from portugal. | forty methicillin-resistant and -susceptible staphylococcus pseudintermedius (mrsp and mssp, respectively) from colonization and infection in dogs and cats were characterized for clonality, antimicrobial, and biocide susceptibility. mssp were genetically more diverse than mrsp by multi-locus sequence typing and pulsed-field gel electrophoresis. three different spa types (t06, t02, t05) and two sccmec types (ii-iii and v) were detected in the mrsp isolates. all mrsp and two mssp strains were mult ... | 2014 | 23819785 |
molecular characterization of the multiple interactions of spsd, a surface protein from staphylococcus pseudintermedius, with host extracellular matrix proteins. | staphylococcus pseudintermedius, a commensal and pathogen of dogs and occasionally of humans, expresses surface proteins potentially involved in host colonization and pathogenesis. here, we describe the cloning and characterization of spsd, a surface protein of s. pseudintermedius reported as interacting with extracellular matrix proteins and corneocytes. a ligand screen and western immunoblotting revealed that the n-terminal a domain of spsd bound fibrinogen, fibronectin, elastin and cytokerati ... | 2013 | 23805283 |
genome sequence of methicillin-resistant staphylococcus pseudintermedius sequence type 233 (st233) strain k7, of human origin. | we report the genome sequence of the methicillin-resistant staphylococcus pseudintermedius strain k7, isolated from the nares of a veterinarian in seoul, south korea. | 2013 | 23788539 |
in vitro efficacy of the essential oil from leptospermum scoparium (manuka) on antimicrobial susceptibility and biofilm formation in staphylococcus pseudintermedius isolates from dogs. | staphylococcus pseudintermedius is a common pathogen of skin and ear infections in dogs. the widespread and rapid emergence of meticillin-resistant s. pseudintermedius (mrsp) has created therapeutic challenges in veterinary medicine and the need for alternative treatments. | 2013 | 23772881 |
methicillin-resistant staphylococcus pseudintermedius as causative agent of dairy cow mastitis. | | 2013 | 23723102 |
multi-drug and methicillin resistance of staphylococci from canine patients at a veterinary teaching hospital (2006-2011). | over the past 10 years, an increase in methicillin and multi-drug resistant staphylococcal species has been identified worldwide and anecdotally reported within our veterinary teaching hospital. | 2013 | 23721478 |
antimicrobial resistance, virulence genes, and genetic lineages of staphylococcus pseudintermedius in healthy dogs in tunisia. | nasal swabs of 100 healthy dogs were obtained in 2011 in tunisia and tested for staphylococcus pseudintermedius recovery. antimicrobial resistance profile and virulence gene content were determined. multilocus-sequence-typing (mlst) and smai-pulsed-field gel electrophoresis (pfge) were investigated. s. pseudintermedius was recovered in 55 of the 100 tested samples (55 %), and one isolate per sample was further studied. all 55 s. pseudintermedius isolates were susceptible to methicillin (mssp) bu ... | 2013 | 23686400 |
prevalence of staphylococcal enterotoxins in staphylococcus pseudintermedius isolates from dogs with pyoderma and healthy dogs. | to investigate the role of staphylococcal enterotoxins (ses) produced by staphylococcus pseudintermedius in the pathogenesis of pyoderma, isolates from dogs with pyoderma and healthy dogs were analyzed. according to reverse passive latex agglutination, 14/184 isolates (7.6%) from dogs with pyoderma and 9/87 (10.3%) from healthy dogs produced ses (sea, sec or sed). according to multiplex pcr, 99 isolates (53.7%) from dogs with pyoderma and 97 (90.8%) from healthy dogs possessed one or more se gen ... | 2013 | 23659343 |
staphylococcus pseudintermedius heterogeneously expresses the meca gene. | | 2013 | 23642412 |
characterization of the biofilm forming ability of staphylococcus pseudintermedius from dogs. | staphylococcus pseudintermedius is an opportunistic pathogen of dogs and has emerged as a leading cause of skin, wound and surgical site infections worldwide. methicillin resistance is common and clinical infections as a result of methicillin-resistant s. pseudintermedius (mrsp) pose a clinical challenge. in other staphylococci, biofilm formation has been shown to be a virulence factor for infection, however, it has received little attention in s. pseudintermedius. the objectives of this study w ... | 2013 | 23641755 |
may staphylococcus pseudintermedius be non-haemolytic? | | 2013 | 23618797 |
characterization of methicillin-resistant staphylococcus pseudintermedius isolated from dogs and cats. | the aim of this study was to explore the presence of methicillin-resistant staphylococcus pseudintermedius (mrsp) in a collection of s. pseudintermedius strains isolated from dogs and cats with dermatitis in japan and to compare their genotypic and phenotypic characteristics. clonal relationships were determined by pulse field gel electrophoresis (pfge), staphylococcal chromosomal cassette mec (sccmec) typing, and multilocus sequence typing (mlst). biofilm formation assay was performed using saf ... | 2013 | 23607810 |
genome sequence of staphylococcus pseudintermedius strain e140, an st71 european-associated methicillin-resistant isolate. | we report the first genome sequence of the methicillin-resistant staphylococcus pseudintermedius (mrsp) strain e140, isolated from a canine bite wound infection in denmark. this strain represents the dominant clonal lineage associated with canine mrsp infections in europe. | 2013 | 23516230 |
methicillin-resistant staphylococcus pseudintermedius infection in a bone marrow transplant recipient. | staphylococcus pseudintermedius is a veterinary pathogen that has seldom been described as an agent of human disease. features of this probably underreported coagulase-positive staphylococcus species are depicted here through the description of a graft-versus-host disease-related wound infection caused by a multidrug-resistant strain. | 2013 | 23486715 |
successful treatment of encrusted cystitis associated with staphylococcus pseudintermedius infection in the urinary bladder of a dog. | a 5-year-old female spayed mixed-breed dog was examined because of signs of persistent stranguria following treatment for urethral obstruction. | 2013 | 23445291 |
residual antibacterial activity of dog hairs after therapy with antimicrobial shampoos. | topical antimicrobial treatment for canine pyoderma is becoming increasingly important, but little is known about the mechanism of action and persistence of activity of antimicrobial shampoos. | 2013 | 23432432 |
usefulness of cefovecin disk-diffusion test for predicting meca gene-containing strains of staphylococcus pseudintermedius and clinical efficacy of cefovecin in dogs with superficial pyoderma. | cefovecin has been widely used to treat skin infections in dogs. the relationship of the cefovecin disk-diffusion test results to the presence of the meca gene and the clinical efficacy of cefovecin have not been fully evaluated. | 2013 | 23331693 |
in vitro antiseptic susceptibilities for staphylococcus pseudintermedius isolated from canine superficial pyoderma in japan. | topical therapy, particularly with chlorhexidine, is becoming increasingly common as a treatment option for canine pyoderma; however, there are limited studies on the susceptibility of staphylococcus pseudintermedius to chlorhexidine compounds. | 2013 | 23331688 |
serum anti-staphylococcus pseudintermedius ige and igg antibodies in dogs with atopic dermatitis and nonatopic dogs. | dogs and humans with atopic dermatitis (ad) are predisposed to colonization and recurrent infection with staphylococcus spp. studies in humans suggest that staphylococcus-specific immunoglobulin e (ige) plays a key role in disease pathogenesis. few such studies have been undertaken in dogs. | 2013 | 23331675 |
pathogenicity potential of staphylococcus pseudintermedius strains isolated from canine carriers and from dogs with infection signs. | | 2013 | 23328490 |
methicillin-resistant staphylococcus pseudintermedius in rats. | | 2013 | 23260061 |
feasibility of magnetic resonance electrical impedance tomography (mreit) conductivity imaging to evaluate brain abscess lesion: in vivo canine model. | to show the feasibility of magnetic resonance electrical impedance tomography (mreit) conductivity imaging in terms of its capability to provide new contrast information of abscess lesion and characterize time-course variations before and after the induction of brain abscess. | 2013 | 23239506 |
multilocus sequence typing for characterization of staphylococcus pseudintermedius. | staphylococcus pseudintermedius is an opportunistic pathogen in dogs. four housekeeping genes with allelic polymorphisms were identified and used to develop an expanded multilocus sequence typing (mlst) scheme. the new seven-locus technique shows s. pseudintermedius to have greater genetic diversity than previous methods and discriminates more isolates based upon host origin. | 2013 | 23115265 |
evaluation of minocycline susceptibility of methicillin-resistant staphylococcus pseudintermedius. | methicillin-resistant staphylococcus pseudintermedius (mrsp) is an increasingly important cause of opportunistic infections in dogs and cats. treatment options are often limited because of the high level of antimicrobial resistance. doxycycline resistance is common, but variable mechanisms of doxycycline resistance exist, with some conferring resistance to doxycycline but not minocycline. however, there has been limited study of minocycline susceptibility in clinical mrsp isolates nor has the as ... | 2013 | 23107659 |
transcription of canine toll-like receptor 2, β-defensin 1 and β-defensin 103 in infected atopic skin, non-infected atopic skin, healthy skin and the cpek cell line. | dogs and humans with atopic dermatitis (ad) have a high prevalence of recurrent staphylococcal pyoderma. β-defensins (bds) and toll-like receptors (tlrs) are important in innate immunity against bacterial skin infections, and decreased bd and tlr2 expression has been associated with human ad. however, findings from recent studies of bd expression in human and canine ad have been variable and contradictory. the aim of this study was to further our understanding of the role of antimicrobial protei ... | 2013 | 23067725 |
in vitro evaluation of topical biocide and antimicrobial susceptibility of staphylococcus pseudintermedius from dogs. | staphylococcus pseudintermedius is an important canine pathogen, and the emergence and widespread dissemination of meticillin-resistant strains (mrsp) is of significant concern. multidrug-resistant infections may require alternative approaches, such as the use of topical therapy. there is minimal information about the in vitro susceptibility of meticillin-susceptible s. pseudintermedius (mssp) and mrsp to biocides and topical antimicrobials. | 2012 | 23050904 |
multi-resistant staphylococcus pseudintermedius: a wake-up call in our approach to bacterial infection. | | 2012 | 22931397 |
methicillin-resistant staphylococcus pseudintermedius in sweden. | staphylococcus pseudintermedius is an opportunistic pathogen that is one of the most frequent causes of infections in dogs. in europe, there are increasing reports of methicillin-resistant s. pseudintermedius (mrsp), and in sweden, mrsp has also been more frequently isolated during recent years. however, there is limited knowledge regarding the epidemiology and genetic relationship among the swedish isolates. this study therefore investigated the genetic relationship of mrsp isolated from compan ... | 2012 | 22931056 |
prevalence and characterization of methicillin-resistant staphylococcus pseudintermedius in pets from south china. | the aim of this study was to determine the presence of and characterize methicillin-resistant staphylococcus pseudintermedius (mrsp) isolated from pets in south china. from 2007 to 2009, 898 samples were collected from 785 pets in guangdong province. the identity of staphylococcal species and the presence of methicillin resistance were confirmed by phenotypic and genotypic assays. the genetic relationships of mrsp isolates were determined by multilocus sequence typing (mlst), pfge and spa typing ... | 2012 | 22770517 |
staphylococcus pseudintermedius colonization patterns and strain diversity in healthy dogs: a cross-sectional and longitudinal study. | this is the first large-scale study of staphylococcus pseudintermedius colonization and diversity in healthy dogs where samples were collected over a long time and strains were identified by pcr according to the current taxonomy of the s. intermedius group and typed by a highly discriminatory method such as pulsed field gel electrophoresis (pfge). a cross-sectional study of nasal, oral, perineal and inguinal carriage in 119 healthy dogs was followed by a longitudinal study where oral and perinea ... | 2012 | 22770516 |
factors associated with methicillin-resistant versus methicillin-susceptible staphylococcus pseudintermedius infection in dogs. | to compare methicillin-resistant staphylococcus pseudintermedius (mrsp) and methicillin-susceptible s pseudintermedius (mssp) infections in dogs. | 2012 | 22657928 |
misuse of antimicrobials and selection of methicillin-resistant staphylococcus pseudintermedius strains in breeding kennels: genetic characterization of bacteria after a two-year interval. | methicillin-resistant staphylococcus pseudintermedius (mrsp) strains have been isolated from dogs with increasing frequency; prolonged or excessive use of antimicrobials is associated with the selection of mrsp, and misuse of antimicrobials is frequent in breeding kennels. this study was carried out in two breeding kennels (a and b) in which we had isolated mrsp in 2008: the aim was to assess colonization of previously positive bitches and of other bitches sharing the same environment and to ass ... | 2013 | 22551469 |
meticillin-resistant staphylococcus pseudintermedius: clinical challenge and treatment options. | meticillin-resistant staphylococcus pseudintermedius (mrsp) has emerged as a major therapeutic challenge for small animal veterinarians over the past 10 years and continues to spread worryingly in many countries. this review focuses on the clinical aspects of mrsp infections seen in patients with skin disease and on currently available treatment options. in addition, it discusses the implications for in-contact people, other animals and the environment, because infection control strategies are l ... | 2012 | 22486942 |
carriage of methicillin-resistant staphylococcus pseudintermedius in dogs--a longitudinal study. | methicillin-resistant s. pseudintermedius strains (mrsp) are reported with increasing frequency in bacterial cultures from dogs. the objectives of this study were to determine whether mrsp could be found in dogs several months after a clinically apparent infection and whether the length of carriage varied depending on systemic antimicrobial treatment, diagnosis at time of the first positive mrsp culture and the presence of skin disease or wounds. thirty-one dogs previously diagnosed with a clini ... | 2012 | 22444911 |
comparative mutant prevention concentration and mechanism of resistance to veterinary fluoroquinolones in staphylococcus pseudintermedius. | the problem of antibacterial drug resistance is increasing worldwide, in part due to the therapeutic concentrations currently used based on the minimal inhibitory concentration (mic) as a measure of potency are often the very concentrations required to selectively enrich the resistant mutant portion of the population. a mutant prevention concentration (mpc)-based dosing strategy is suggested to improve the therapeutic outcome based on the mic. | 2012 | 22409306 |
antibiotic treatments of a methicillin-resistant staphylococcus pseudintermedius infection in a dog: a case presentation. | | 2012 | 22378055 |
treatment outcome of dogs with meticillin-resistant and meticillin-susceptible staphylococcus pseudintermedius pyoderma. | the prevalence of meticillin- and multidrug-resistant staphylococcus pseudintermedius (mrsp) in canine pyoderma has been increasing in recent years; thus, treatment of these cases has become challenging. | 2012 | 22364681 |
clonal diversity and biofilm-forming ability of methicillin-resistant staphylococcus pseudintermedius. | the aim of this study was to investigate the clonal epidemiology of methicillin-resistant staphylococcus pseudintermedius (mrsp) isolates from dogs in norway and to evaluate the antimicrobial resistance patterns and determine the biofilm-forming abilities of the isolates. | 2012 | 22258925 |
validity of somatic cell count as indicator of pathogen-specific intramammary infections. | the objective of this study was to determine whether somatic cell count (scc) was an effective test, with a sensitivity exceeding 85%, to determine species-specific bacterial infections. in addition, the relation between the scc and various udder pathogen groups was investigated. scc thresholds of greater than 200 000 cells/ml were used in quarter and greater than 150 000 cells/ml in composite milk samples. a retrospective study was conducted on a data set for 89 635 quarter and 345 467 composit ... | 2017 | 28470079 |
skin infection caused by a novel strain of staphylococcus pseudintermedius in a siberian husky dog owner. | introduction.staphylococcus pseudintermedius, an opportunistic pathogen of dogs and cats, is rarely reported to cause infection in humans. here, we describe a case of severe skin infection caused by s. pseudintermedius, in a 47-year-old male, a dog owner; to the best of our knowledge, this is the first such case reported from scotland. case presentation. the patient presented with a short history of a severe ecthyma-like lesion on his forehead, with smaller lesions on his abdomen and legs. bacte ... | 2017 | 28663821 |
the in vitro antibacterial activity of incomplete iron salt of polyacrylic acid against pseudomonas aeruginosa, meticillin-resistant staphylococcus pseudintermedius and meticillin-resistant s. aureus. | the incomplete iron salt of polyacrylic acid (iis-paa) has been used for its haemostatic, wound healing and antibacterial properties in human patients. iis-paa is a water-soluble, acidic, hydrophilic polymer that is active at ph 2.9-4.0. | 2017 | 28833656 |
bacterial recovery using sonication versus swabbing of titanium and stainless steel implants inoculated with staphylococcus pseudintermedius or pseudomonas aeruginosa. | to evaluate the use of sonication to improve recovery of bacteria from metal discs infected with bacteria commonly associated with implant infections in veterinary medicine. | 2017 | 28763526 |
a spinal infection with staphylococcus pseudintermedius. | we present a case of a 60-year-old woman with an invasive spinal infection with staphylococcus pseudintermedius associated with a 15-year-old spinal fixation device and epidemiological contact with dogs. it was confirmed on blood culture and culture from pus from the epidural abscess and successfully treated using similar treatment as for a staphylococcus aureus infection - 6 weeks of intravenous flucloxacillin 2 g four times daily with a 6 week follow-on course of oral clindamycin 450 mg three ... | 2017 | 28784907 |
prevalence of methicillin-resistant staphylococcus aureus from equine nasopharyngeal and guttural pouch wash samples. | methicillin-resistant staphylococcus aureus (mrsa) is recognized as a cause of nosocomial infections in both human and veterinary medicine. studies that examine the nasopharynx and guttural pouches of the horse as carriage sites for mrsa have not been reported. | 2017 | 28661019 |
in vitro bactericidal activity of blue light (465 nm) phototherapy on meticillin-susceptible and meticillin-resistant staphylococcus pseudintermedius. | staphylococcus pseudintermedius is the most common cause of bacterial skin infections in dogs. meticillin-resistant infections have become more common and are challenging to treat. blue light phototherapy may be an option for treating these infections. | 2017 | 28543810 |
patterns and predictors of antimicrobial resistance among staphylococcus spp. from canine clinical cases presented at a veterinary academic hospital in south africa. | antimicrobial resistance in staphylococci, often associated with treatment failure, is increasingly reported in veterinary medicine. the aim of this study was to investigate patterns and predictors of antimicrobial resistance among staphylococcus spp. isolates from canine samples submitted to the bacteriology laboratory at the university of pretoria academic veterinary hospital between 2007 and 2012. retrospective data of 334 staphylococcus isolates were used to calculate the proportion of sampl ... | 2017 | 28454567 |
development of a real-time pcr for detection of staphylococcus pseudintermedius using a novel automated comparison of whole-genome sequences. | staphylococcus pseudintermedius is an opportunistic pathogen in dogs and cats and occasionally causes infections in humans. s. pseudintermedius is often resistant to multiple classes of antimicrobials. it requires a reliable detection so that it is not misidentified as s. aureus. phenotypic and currently-used molecular-based diagnostic assays lack specificity or are labour-intensive using multiplex pcr or nucleic acid sequencing. the aim of this study was to identify a specific target for real-t ... | 2017 | 28859126 |
taurolidine susceptibility of methicillin-resistant staphylococcus pseudintermedius isolates. | infections caused by methicillin-resistant staphylococcus pseudintermedius (mrsp) can be challenging to treat because they are often resistant to many other antimicrobial agents. we assessed the susceptibility of 29 mrsp isolates from dogs to taurolidine in vitro. there was no growth at 0.12% taurolidine and light growth at 0.06% for all isolates. taurolidine was reliable at inhibiting growth of mrsp at a concentration of 1,200 µg/ml. | 2017 | 28754087 |
direct repeat unit (dru) typing and antimicrobial resistance of methicillin-resistant staphylococcus pseudintermedius isolated from dogs in atlantic canada. | there are few reports investigating the characterization of methicillin-resistant staphylococcus pseudintermedius (mrsp) in dogs in canada and none from atlantic canada. the objectives of this study were to strain type mrsp isolates cultured at a regional diagnostic laboratory using direct repeat unit (dru) typing and to describe their antimicrobial resistance profiles. ninety-four isolates recovered from dogs between 2010 and 2012 had dru typing, cluster analysis, and antimicrobial susceptibili ... | 2017 | 28725109 |
molecular characteristics of clinical methicillin-resistant staphylococcus pseudintermedius harboring arginine catabolic mobile element (acme) from dogs and cats. | this study aimed to investigate the presence of arginine catabolic mobile element (acme) and its associated molecular characteristics in methicillin-resistant staphylococcus pseudintermedius (mrsp). among the 72 s. pseudintermedius recovered from various infection sites of dogs and cats, 52 (72.2%) were mrsp. acme-arca was detected commonly (69.2%) in these mrsp isolates, and was more frequently detected in those from the skin than from other body sites (p=0.047). there was a wide genetic divers ... | 2017 | 28697875 |
high-resolution melting analysis of gyra codon 84 and grla codon 80 mutations conferring resistance to fluoroquinolones in staphylococcus pseudintermedius isolates from canine clinical samples. | staphylococcus pseudintermedius is an opportunistic pathogen of dogs and cats. a high-resolution melting analysis (hrma) protocol was designed and tested on 42 clinical isolates with known fluoroquinolone (fq) susceptibility and gyra codon 84 and grla codon 80 mutation status. the hrma approach was able to discriminate between fq-sensitive and fq-resistant strains and confirmed previous reports that the main mutation site associated with fq resistance in s. pseudintermedius is located at positio ... | 2017 | 28578596 |
clonal complexes and antimicrobial susceptibility profiles of staphylococcus pseudintermedius isolates from dogs in the united states. | staphylococcus pseudintermedius is the primary cause of canine pyoderma and has been associated with diseases in other animals, including human beings. a high prevalence of methicillin and multidrug resistance has been reported in this bacterium in some geographic regions of the united states. multilocus sequence type (mlst) 68 was implicated, initially, as the major clonal genotype based on a limited number of samples. the objectives of this study were to determine the population genetics of s. ... | 2017 | 28504897 |
in vitro comparison of the dermal penetration of three different topical formulations containing lasalocid. | topical antimicrobial preparations are of utmost importance in treating suspected and confirmed meticillin-resistant staphylococcus pseudintermedius (mrsp) infections due to the increasing incidence of widespread resistance to systemic antimicrobials. lasalocid is active against mrsp in vitro and this may become an important topical antimicrobial for the treatment of canine pyoderma. | 2017 | 28470877 |
survival of staphylococcus pseudintermedius in modified romanowsky staining solutions. | stains that are used regularly for patient-side diagnosis to rapidly identify bacterial and fungal infections could become contaminated by common pathogens, such as staphylococcus pseudintermedius, during slide immersion. | 2017 | 28470871 |
antimicrobial resistance in coagulase-positive staphylococci isolated from companion animals in australia: a one year study. | methicillin-resistant coagulase-positive staphylococci (cops) have become increasingly recognised as opportunistic pathogens that limit therapeutic options in companion animals. the frequency of methicillin resistance amongst clinical isolates on an australia-wide level is unknown. this study determined antimicrobial susceptibility patterns for cops isolated from clinical infections in companion animals (dogs, cats and horses) as part of the first nation-wide survey on antimicrobial resistance i ... | 2017 | 28430811 |