Publications
Title | Abstract | Year(sorted ascending) Filter | PMID Filter |
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zaragozic acids: a family of fungal metabolites that are picomolar competitive inhibitors of squalene synthase. | three closely related fungal metabolites, zaragozic acids a, b, and c, that are potent inhibitors of squalene synthase have been isolated and characterized. zaragozic acids a, b, and c were produced from an unidentified sterile fungal culture, sporormiella intermedia, and leptodontium elatius, respectively. the structures of the zaragozic acids and their trimethyl esters were determined by a combination of physical and chemical techniques. the zaragozic acids are characterized by a novel 2,8-dio ... | 1993 | 8419946 |