structure of methyl adenophorate and triphyllol, triterpenoids of adenophora triphylla var. japonica roots. | from the crude drug "shajin", the roots of adenophora triphylla var. japonica, two novel triterpenoids, methyl adenophorate and triphyllol, have been isolated and these structures have been determined as those represented by formula i and ii, respectively, on the basis of chemical and physical evidence. | 1981 | 17401973 |
polyhydroxylated pyrrolidine and piperidine alkaloids from adenophora triphylla var. japonica (campanulaceae). | adenophora triphylla var. japonica (campanulaceae) yielded two new alkaloids, the 6-c-butyl derivative of 2r,5r-bis(hydroxymethyl)-3r,4r-dihydroxypyrrolidine (dmdp) and alpha-1-c-ethyl-fagomine, together with the known alkaloids 1,4-dideoxy-1,4-imino-d-arabinitol, 1-deoxynojirimycin, and 1-deoxymannojirimycin. 6-c-butyl-dmdp showed inhibitory activity toward almond beta-glucosidase (ic50 = 68 microm), whereas alpha-1-c-ethyl-fagomine inhibited bovine liver beta-galactosidase (ic50 = 29 microm). | 2000 | 10703061 |