Publications
| complete nucleotide sequences and genome organization of four chimpanzee adenoviruses. | the complete nucleotide sequences for four adenoviruses-simian adenoviruses 21, 22, 23, and 24, originally isolated from chimpanzees, were determined. the genome organization of the chimpanzee adenoviruses was found to be similar to that of other adenoviruses. the viral gene products of the adenoviruses simian adenoviruses 22, 23, and 24 are very closely related to those of the (previously sequenced) chimpanzee adenovirus simian adenovirus 25. simian adenovirus 21 is most similar to human subgro ... | 2004 | 15207622 |
| generation of an adenoviral vaccine vector based on simian adenovirus 21. | adenoviral vectors can be used to generate potent humoral and cellular immune responses to transgene products. use of adenoviral vectors based on non-human isolates may allow for their utilization in populations harbouring neutralizing antibodies to common human serotypes. a vector chimera was constructed using simian adenovirus 22 (a serotype belonging to the species human adenovirus e) and simian adenovirus 21 (a serotype belonging to the species human adenovirus b) expressing the ebola (zaire ... | 2006 | 16894185 |