| dietary glucosinolates sulforaphane, phenethyl isothiocyanate, indole-3-carbinol/3,3'-diindolylmethane: anti-oxidative stress/inflammation, nrf2, epigenetics/epigenomics and in vivo cancer chemopreventive efficacy. | glucosinolates are a group of sulfur-containing glycosides found in many plant species, including cruciferous vegetables such as broccoli, cabbage, brussels sprouts, and cauliflower. accumulating evidence increasingly supports the beneficial effects of dietary glucosinolates on overall health, including as potential anti-cancer agents, because of their role in the prevention of the initiation of carcinogenesis via the induction of cellular defense detoxifying/antioxidant enzymes and their epigen ... | 0 | 26457242 |
| ethyl propiolate as a post-column derivatization reagent for thiols: development of a green liquid chromatographic method for the determination of glutathione in vegetables. | the present study reports the development, validation and application of a new green liquid chromatographic method for the determination of glutathione (gsh) in vegetable samples. in this work we introduce-for the first time-ethyl propiolate (ep) as an advantageous post-column derivatization reagent for thiolic compounds. gsh (t(r)=6.60 min) and n-acetylcysteine (nac, internal standard) (t(r)=11.80 min) were separated efficiently from matrix endogenous compounds by using a 100% aqueous mobile ph ... | 2011 | 21414445 |
| the brassica epithionitrile 1-cyano-2,3-epithiopropane triggers cell death in human liver cancer cells in vitro. | glucosinolates are secondary metabolites present in brassica vegetables. alkenyl glucosinolates are enzymatically degraded forming nitriles or isothiocyanates, but in the presence of epithiospecifier protein, epithionitriles are released. however, studies on the occurrence of epithionitriles in brassica food and knowledge about their biological effects are scarce. | 0 | 26251050 |
| the table maneuver: a procedure used with success in four cases of unconscious choking older subjects. | confronted with an unconscious choking victim, it is recommended to call an ambulance and start mouth-to-mouth and cardiopulmonary resuscitation (cpr). we describe a procedure called the "table maneuver" that was successful in relieving foreign-body airway obstruction in 4 cases of choking in unconscious elderly patients over a 6-year period in the same long-term care facility. | 2010 | 20870197 |
| quantitative determination of glucoraphanin in brassica vegetables by micellar electrokinetic capillary chromatography. | glucoraphanin, a glucosinolate, is found naturally in plants and is present in relatively high concentrations in broccoli. glucosinolates have received much attention as studies have indicated that a diet rich in them may provide some protection from certain cancers. a micellar electrokinetic chromatography (mekc) method using sodium cholate as the micellar phase has been developed to quantify for glucoraphanin in broccoli (seeds and florets) and brussels sprouts. the glucoraphanin peak elutes j ... | 2010 | 20172104 |
| effect of spray application technology on the biological control of aphids in brussels sprouts. | a field trial was carried out to evaluate different application techniques for crop penetration and biological efficacy of aphid control in brussels sprouts. six different application techniques were tested at a pressure of 4.0 bar in a field trial in 3 parallels at the provincial vegetable research centre in kruishoutem (pcg): a standard iso 02 flat fan nozzle (at 200 l/ha), an iso 04 twin air inclusion nozzle (at 800 l/ha), an iso 03 drift reducing nozzle, an air injection nozzle (airjet,) dro ... | 2010 | 21542477 |
| the antioxidant properties of organosulfur compounds (sulforaphane). | sulforaphane (sfn) is a molecule within the isothiocyanate (itc) group of organosulfur compounds. sfn is a phytochemical commonly found in cruciferous vegetables such as broccoli, brussels sprouts and cabbages. it has been widely studied in order to evaluate its chemopreventive properties and some of those have already been established by means of animal and human models. the sfn induces phase i and ii enzymes involved in detoxification processes of chemical carcinogens in order to prevent the s ... | 0 | 25944116 |
| efficient synthesis of brussalexin a, a remarkable phytoalexin from brussels sprouts. | the synthesis of brussalexin a, the first phytoalexin containing an allyl thiolcarbamate group, and its selective inhibitory activity against fungal plant pathogens is described. | 2007 | 17406713 |
| effect of storage, processing and cooking on glucosinolate content of brassica vegetables. | epidemiological studies have shown that consumption of brassica vegetables decrease the risk of cancer. these associations are linked to dietary intake of glucosinolates and their metabolism to cancer preventive isothiocyanates. bioavailability of glucosinolates and related isothiocyanates are influenced by storage and culinary processing of brassica vegetables. in this work, the content of the 7 major glucosinolates in broccoli, brussels sprouts, cauliflower and green cabbage and their stabilit ... | 2007 | 17011103 |
| bitter taste markers explain variability in vegetable sweetness, bitterness, and intake. | intake of vegetables falls short of recommendations to lower risk of chronic diseases. most research addresses bitterness as a sensory deterrent to consuming vegetables. we examined bitter and sweet sensations from vegetables as mediators of vegetable preference and intake as well as how these tastes vary with markers of genetic variation in taste (3.2 mm 6-n-propylthiouracil bitterness) and taste pathology (1.0 mm quinine bitterness, chorda tympani nerve relative to whole mouth). seventy-one fe ... | 2006 | 16368118 |
| low levels of 3,3'-diindolylmethane activate estrogen receptor α and induce proliferation of breast cancer cells in the absence of estradiol. | 3,3'-diindolylmethane (dim) is an acid-catalyzed dimer of idole-3-carbinol (i3c), a phytochemical found in cruciferous vegetables that include broccoli, brussels sprouts and cabbage. dim is an aryl hydrocarbon receptor (ahr) ligand and a potential anticancer agent, namely for the treatment of breast cancer. it is also advertised as a compound that regulates sex hormone homeostasis. | 2014 | 25048790 |
| impact of selenium supply on se-methylselenocysteine and glucosinolate accumulation in selenium-biofortified brassica sprouts. | brassica sprouts are widely marketed as functional foods. here we examined the effects of se treatment on the accumulation of anticancer compound se-methylselenocysteine (semscys) and glucosinolates in brassica sprouts. cultivars from the six most extensively consumed brassica vegetables (broccoli, cauliflower, green cabbage, chinese cabbage, kale, and brussels sprouts) were used. we found that se-biofortified brassica sprouts all were able to synthesize significant amounts of semscys. analysis ... | 2014 | 25038715 |
| the antiproliferative response of indole-3-carbinol in human melanoma cells is triggered by an interaction with nedd4-1 and disruption of wild-type pten degradation. | human melanoma cells displaying distinct pten genotypes were used to assess the cellular role of this important tumor-suppressor protein in the antiproliferative response induced by the chemopreventative agent indole-3-carbinol (i3c), a natural indolecarbinol compound derived from the breakdown of glucobrassicin produced in cruciferous vegetables such as broccoli and brussels sprouts. i3c induced a g1-phase cell-cycle arrest and apoptosis by stabilization of pten in human melanoma cells that exp ... | 2014 | 25009292 |
| attenuation of carcinogenesis and the mechanism underlying by the influence of indole-3-carbinol and its metabolite 3,3'-diindolylmethane: a therapeutic marvel. | rising evidence provides credible support towards the potential role of bioactive products derived from cruciferous vegetables such as broccoli, cauliflower, kale, cabbage, brussels sprouts, turnips, kohlrabi, bok choy, and radishes. many epidemiological studies point out that brassica vegetable protects humans against cancer since they are rich sources of glucosinolates in addition to possessing a high content of flavonoids, vitamins, and mineral nutrients. indole-3-carbinol (i3c) belongs to th ... | 2014 | 24982671 |
| environmental and other risk factors for colorectal carcinogenesis. | diet plays a role in the risk of colon cancer, but exactly how it affects risk is unknown. in western countries diet is low in fibre and high in animal protein, fats and refined carbohydrates such as sugar. risk seems to be reduced by a diet high in calcium, vitamin d and vegetables such as brussels sprouts, cabbage and broccoli. familial polyposis has been studied sufficiently and increases the risk of colon cancer. moreover, in relatives there is frequently a familial history of an increased i ... | 2004 | 15655649 |
| cutting brussels sprouts: collaboration involving persons with dementia. | how people with dementia collaborate with other people is an area in need of more research and conceptualizations. collaboration introduces a number of new possibilities and demands concerning cognitive and linguistic abilities and it is suggested that a theoretical framework that emphasize that cognitive resources are not exclusively individual, but are part of cognitive and communicative context. in this article focus is on joint activities and their collaborative organization is analyzed usin ... | 2014 | 24655679 |
| associative conditioning can increase liking for and consumption of brussels sprouts in children aged 3 to 5 years. | pairing foods with liked flavors repeatedly can increase preferences for those foods. we compared the effectiveness of associative conditioning (pairing vegetables with sweetened and unsweetened cream cheese) and exposure (presenting vegetables alone) in increasing liking and consumption of bitter and nonbitter vegetables. twenty-nine children (aged 3 to 5 years) participated in the study. one group of children received brussels sprouts (bitter) with sweetened cream cheese and cauliflower (nonbi ... | 2014 | 24439970 |
| urinary 3,3'-diindolylmethane: a biomarker of glucobrassicin exposure and indole-3-carbinol uptake in humans. | brassica vegetable consumption may confer a protective effect against cancer, possibly attributable to their glucosinolates. glucobrassicin is a predominant glucosinolate and is the precursor of indole-3-carbinol (i3c), a compound with anticancer effects. however, objective assessments of i3c uptake from brassica vegetables have not been successful. | 2014 | 24357105 |
| diet and toenail arsenic concentrations in a new hampshire population with arsenic-containing water. | limited data exist on the contribution of dietary sources of arsenic to an individual's total exposure, particularly in populations with exposure via drinking water. here, the association between diet and toenail arsenic concentrations (a long-term biomarker of exposure) was evaluated for individuals with measured household tap water arsenic. foods known to be high in arsenic, including rice and seafood, were of particular interest. | 2013 | 24237880 |
| effects of brussels sprouts and their phytochemical components on oxidative stress-induced neuronal damages in pc12 cells and icr mice. | in this study, the protective effects of brussels sprouts extract and its major constituents against oxidative stress-induced damages were investigated in rat pheochromocytoma cells and institute of cancer research mice. the major constituents of brussels sprouts (3,4',5,7-tetrahydroxyflavone (kaempferol), indole-3-carbinol, and phenethyl isothiocyanate) were selectively tested. of these, the flavonoid compound, kaempferol exhibited the highest potency in radical scavenging activity (1,1-dipheny ... | 2013 | 24175656 |
| sinigrin inhibits production of inflammatory mediators by suppressing nf-κb/mapk pathways or nlrp3 inflammasome activation in macrophages. | sinigrin (2-propenyl glucosinolate) is found mainly in broccoli, brussels sprouts, and black mustard seeds. recently, sinigrin has received attention for its role in disease prevention and health. this study investigated the effect of sinigrin on macrophage function, including the activity of nod-like receptor protein 3 (nlrp3) inflammasome. in a concentration-dependent manner, sinigrin inhibited lipopolysaccharide (lps)-induced nitric oxide (no) production and the expression of cox-2 and prosta ... | 2017 | 28219839 |
| pesticide usage in some vegetable crops in great britain: real on-farm applications. | the last decade has seen an increasing requirement throughout the united kingdom (uk) for accurate, timely information on pesticide usage on fresh produce such as vegetables to satisfy government legislation and provide data as part of the registration and review process of pesticides. these data, collected by the department for environment, food and rural affair's pesticide usage survey group (pusg), provide information on current and past usage patterns and allow the impact of use on the envir ... | 2003 | 12741528 |
| sinigrin and its therapeutic benefits. | sinigrin (allyl-glucosinolate or 2-propenyl-glucosinolate) is a natural aliphatic glucosinolate present in plants of the brassicaceae family, such as broccoli and brussels sprouts, and the seeds of brassica nigra (mustard seeds) which contain high amounts of sinigrin. since ancient times, mustard has been used by mankind for its culinary, as well as medicinal, properties. it has been systematically described and evaluated in the classical ayurvedic texts. studies conducted on the pharmacological ... | 2016 | 27043505 |
| relationship between food preferences and prop taster status of college students. | how food tastes plays a key role in our food choices and eating behavior, with important implications for health and nutrition. the negative relationship of genetically predisposed sensitivity to 6-n-propylthiouracil (prop) and food preferences for bitter, creamy, and spicy foods, and alcohol is often reported in both scholarly and popular literature. our review of research indicates the empirical results are far from conclusive. we conducted a questionnaire-based study to examine enjoyment rati ... | 2013 | 23648895 |
| nutritional quality of sous vide cooked carrots and brussels sprouts. | phytochemicals (carotenoids, phenolic compounds, and ascorbic acid) and antioxidant capacity (measured by teac, frap, and trap assays) were evaluated on carrots and brussels sprouts sous vide processed and then stored refrigerated for 1, 5, and 10 days and compared with the corresponding raw and oven-steamed products. data showed that sous vide cooked carrots had higher amounts of carotenoids, phenolic compounds, and ascorbic acid than steamed products, and only a slight decrease of phenolic com ... | 2012 | 22568492 |
| modeling the impact of plant structure on host-finding behavior of parasitoids. | for many parasitoid species, the final step of host location occurs on plants whose structure varies in time and space, altering the capacity of parasitoids to exploit hosts. plant structure can be defined by its size, heterogeneity and connectivity. we tested the hypothesis that these three components and all possible interactions affect the level of parasitism of trichogramma evanescens and that parasitism can be predicted if the structure of a plant is measured. we quantified and varied the s ... | 2002 | 28547046 |
| sulforaphane, a natural constituent of broccoli, prevents cell death and inflammation in nephropathy. | cisplatin (cis-diamminedichloroplatinum ii, cis) is a potent and widely used chemotherapeutic agent to treat various malignancies, but its therapeutic use is limited because of dose-dependent nephrotoxicity. cell death and inflammation play a key role in the development and progression of cis-induced nephropathy. sulforaphane (sfn), a natural constituent of cruciferous vegetables such as broccoli, brussels sprouts, etc., has been shown to exert various protective effects in models of tissue inju ... | 2012 | 21684138 |
| broccoli, pten deletion and prostate cancer: where is the link? | the concept that vegetables and fruits are relevant sources of cancer-preventive substances is strongly supported by population studies. among others, cruciferous vegetables like broccoli, cabbage, cauliflower and brussels sprouts are thought to affect the development of various types of cancers and especially prostate tumors. yet, the identification of the molecular mechanisms by which the 'active' compounds contained in these vegetables mediate their anticancer activity has historically lagged ... | 2010 | 21122140 |
| dietary intake of individual glucosinolates in participants of the epic-heidelberg cohort study. | to compile a database on content of individual glucosinolates in food and to describe the dietary intake of individual glucosinolates in a german population. | 2009 | 19295191 |
| role of large cabbage white butterfly male-derived compounds in elicitation of direct and indirect egg-killing defenses in the black mustard. | to successfully exert defenses against herbivores and pathogens plants need to recognize reliable cues produced by their attackers. up to now, few elicitors associated with herbivorous insects have been identified. we have previously shown that accessory reproductive gland secretions associated with eggs of cabbage white butterflies (pieris spp.) induce chemical changes in brussels sprouts plants recruiting egg-killing parasitoids. only secretions of mated female butterflies contain minute amoun ... | 2015 | 26483811 |
| young women's food preferences and taste responsiveness to 6-n-propylthiouracil (prop). | this study examined links between taste responsiveness to 6-n-propylthiouracil (prop), a heritable trait, and sensory responses to six common foods. sixty-three young women subjects were divided into prop tasters (n = 25) and nontasters (n = 25), based on their responses to prop-impregnated filter paper and mean bitterness intensity ratings for seven prop solutions. thirteen subjects were excluded as unclassifiable. the 50 subjects sampled brussels sprouts, broccoli, spinach, black coffee, soy m ... | 2000 | 10764899 |
| taste and food preferences as predictors of dietary practices in young women. | to investigate links between taste responses, self-reported food preferences and selected dietary outcomes in young women. | 1999 | 10656470 |
| in vitro bile acid binding capacities of red leaf lettuce and cruciferous vegetables. | in the present study, we tested the bile acid binding capacity of red leaf lettuce, red cabbage, red kale, green kale, and brussels sprouts through in vitro digestion process by simulating mouth, gastric, and intestinal digestion using six bile acids at physiological ph. green and red kale exhibited significantly higher (86.5 ± 2.9 and 89.7 ± 0.9%, respectively) bile acid binding capacity compared to the other samples. further, three different compositions of bile acids were tested to understand ... | 2017 | 28812344 |
| assessment of heterogeneity in types of vegetables served by main household food preparers and food decision influencers. | while vegetables are often studied as one food group, global measures may mask variation in the types and forms of vegetables preferred by different individuals. to explore preferences for and perceptions of vegetables, we assessed main food preparers based on their preparation of eight specific vegetables and mushrooms. | 2015 | 25850676 |
| the epigenetic impact of cruciferous vegetables on cancer prevention. | the answer to chemoprevention has perhaps been available to the general public since the dawn of time. the epigenetic diet is of extreme interest, for research suggests that cruciferous vegetables are not only an important source of nutrients, but perhaps a key to eliminating cancer as life threatening disease. cruciferous vegetables such as kale, cabbage, brussels sprouts, and broccoli sprouts contain chemical components, such as sulforaphane (sfn) and indole-3-carbinol (i3c), which have been r ... | 2015 | 25774338 |
| brussels sprouts: an exceptionally rich source of ambiguity for anticancer strategies. | | 1998 | 9852997 |
| do dietary phytochemicals with cytochrome p-450 enzyme-inducing activity increase high-density-lipoprotein concentrations in humans? | low plasma concentrations of high-density lipoprotein (hdl) are associated with increased risk of coronary heart disease. several drugs that induce the microsomal cytochrome p-450-dependent enzyme system in liver and intestine, the sites of hdl apolipoprotein (apo) a-i and a-ii synthesis, raise plasma hdl concentrations in humans. to test the hypothesis that phytochemicals with cytochrome p-450-inducing activity may also increase plasma hdl concentrations, two controlled dietary trials were unde ... | 1996 | 8901789 |
| isothiocyanate synthetic analogs: biological activities, structure-activity relationships and synthetic strategies. | sulforaphane is a natural product that is constantly under biological investigation for its unique biological properties. this naturally occurring isothiocyanate (itc) and its analogs are the main components of cruciferous vegetables, such as cauliflower, watercress, broccoli, cabbage, brussels sprouts, widely used as chemopreventive agents. due to their interesting biological profiles, natural itcs have been exploited as starting point to develop new synthetic analogs. the present mini-review b ... | 2014 | 25373847 |
| rapeseed phosphatidylcholine hydrolysis to phosphatidic acid using plant extracts with phopspholipase d. | phosphatidic acid (pa) has a crucial role in cell membrane structure and function. for that reason it has a possible application in the treatment of some health disorders in humans, can be used as a natural and non toxic emulsifier and the component of drug carriers in pharmaceuticals and cosmetics as well as a component for synthesis of some new phospholipids. pa is short-lived in the cell and is difficult to extract directly from the biological material. pa may be easily prepared by hydrolysis ... | 2015 | 26642684 |
| liquid chromatography-mass spectrometry coupled with multivariate analysis for the characterization and discrimination of extractable and nonextractable polyphenols and glucosinolates from red cabbage and brussels sprout waste streams. | nonextractable polyphenol (nep) fractions are usually ignored because conventional extraction methods do not release them from the plant matrix. in this study, we optimized the conditions for sonicated alkaline hydrolysis to the residues left after conventional polyphenol extraction of brussels sprouts top (80°c, 4m naoh, 30min) and stalks (60°c, 4m naoh, 30min), and red cabbage waste streams (80°c, 4m naoh, 45min) to release and characterize the nep fraction. the nep fractions of brussels sprou ... | 2015 | 26008597 |
| effect of polyphenols extracts from brassica vegetables on erythrocyte membranes (in vitro study). | the aim of this work was to estimate the in vitro effects of polyphenol extracts from brassica vegetables (brussels sprouts and red cabbage) on erythrocyte membranes with normal and high concentration of cholesterol. to determine the effect of phenolic compounds we prospectively studied cholesterol concentration, lipid peroxidation, membrane fluidity and atpase activity. polyphenol extracts from brassica vegetables resulted in statistically significant reductions in cholesterol concentrations in ... | 2012 | 23044092 |
| [increased consumption of fruits and vegetables reduces the risk of ischemic heart disease]. | in denmark it is recommended to eat 600 g of fruit and vegetables daily. this recommendation has to a large extent been derived from the demonstrated inverse association with the risk of certain major cancer diseases, while the focus with respect to prevention of ischemic heart disease (ihd) has been directed primarily towards a reduced intake of ''hard'' fats. this systematic review includes prospective studies which have examined the association between the intake of fruit and vegetables, as w ... | 2005 | 16014256 |
| aba promotion of ethylene production in anther culture of brussels sprouts (brassica oleracea var. gemmifera) and its relevance to embryogenesis. | abscisic acid (aba) inhibited embryogenesis in anther culture of brussels sprouts. this was accompanied by enhanced ethylene production during the first half of the anther culture period followed by a reduction in ethylene during the latter half, when compared to anthers not treated with aba. the enhancement of ethylene production by aba 6 h and 48 h after the start of the culture period was counteracted by the ethylene biosynthesis inhibitor aminoethoxyvinylglycine (avg). both avg and the ethyl ... | 1993 | 28741775 |
| quantitative determination of intact glucosinolates in broccoli, broccoli sprouts, brussels sprouts, and cauliflower by high-performance liquid chromatography-electrospray ionization-tandem mass spectrometry. | many methods have been proposed to analyze glucosinolates, a class of phytochemicals whose breakdown products are thought to be responsible for an improvement in health; however, few are quantitative and many are time consuming. a selective and sensitive quantitative method for direct determination of intact glucosinolates was developed using liquid chromatography coupled to electrospray ionization tandem mass spectrometry with selected reaction monitoring detection. detection limits for glucoib ... | 2005 | 15963940 |
| eat your broccoli (and brussels sprouts) | | 1992 | 1557112 |
| taste preference for brussels sprouts: an informal look. | an inquiry of the taste preference of 442 business students for brussels sprouts showed about a 50% dislike of the vegetable, 40% indifference, and a 10% like. some implications of the findings are suggested. | 1991 | 1792285 |
| diet and the irritable bowel syndrome. | food intake plays a key role in triggering or perpetuating symptoms in patients with ibs. evaluation of the impact of diet in the individual patient requires a precise dietary history and a 7-day prospective dietary analysis, which should include the quality and quantity of food consumed, chronologic sequence and nature of symptoms, and the frequency and consistency of bowel movements. the caloric density of the meal, total fat intake, the quantity and quality of lactose-containing foods, sorbit ... | 1991 | 2066155 |
| i don't like it because it eats sprouts: conditioning preferences in children. | although little is known about how preferences develop in childhood, work in adults suggests that evaluative responses to stimuli can be acquired through classical conditioning. in two experiments children were exposed to novel cartoon characters, that were either consistently paired with a picture of a disliked food (brussels sprouts) or a liked food (ice cream). relative preferences for these stimuli (and others) were measured before and after these paired presentations (experiment 1): prefere ... | 2006 | 15885655 |
| metabolism of chlorfenvinphos in both soil and plant of cauliflower and brussels sprouts field crops. | | 1989 | 2597799 |
| [effect of the variety and size of fresh and frozen brussels sprouts on the vitamin c level]. | the content of vitamin c was determined in the following varieties of brussels sprouts: maczuga, citadel f1, lancelot f1 and valiant f1 with diameter 15, 20, 25, 30 and 35 mm. the raw vegetable, the blanched raw sprouts, frozen sprouts immediately after freezing and after 2, 4 and 6 months of frozen storage, and sprouts kept frozen for 6 months and boiled then. the content of vitamin c in the raw vegetable, in the frozen semiproduct, and in the product ready for consumption depended on the varie ... | 1989 | 2634300 |
| nutrient sources in the english diet: quantitative data from three english towns. | diet records from 2402 middle-aged men and women in three english towns have been used to derive food lists which indicate the percentage contribution each food, or group of foods, makes to the intake of specific nutrients. comparison of these food lists with those based on the american diet show differences in sources of nutrients; for example, brussels sprouts provide 5% of the vitamin c intake in our english towns, whereas in the us they provide only 0.3%. it would not be appropriate, therefo ... | 1988 | 3225094 |
| pilot study: effect of 3,3'-diindolylmethane supplements on urinary hormone metabolites in postmenopausal women with a history of early-stage breast cancer. | dietary indoles, present in brassica plants such as cabbage, broccoli, and brussels sprouts, have been shown to provide potential protection against hormone-dependent cancers. 3,3'-diindolylmethane (dim) is under study as one of the main protective indole metabolites. postmenopausal women aged 50-70 yr from marin county, california, with a history of early-stage breast cancer, were screened for interest and eligibility in this pilot study on the effect of absorbable dim (bioresponse-dim) supplem ... | 2004 | 15623462 |
| abnormal n-nonacosane storage in humans: detection by gas chromatography/mass spectrometry of tissue extracts. | we report a case of n-nonacosane storage disease, which went undiagnosed until the death of a 55-year-old farmer. clinical, histological, and biochemical features are discussed. n-nonacosane storage was identified by gas chromatographic-mass spectrometric analysis of different tissue extracts, n-nonacosane concentration reaching 1.2 mg g-1 of lung tissue and 0.32 mg g-1 of liver tissue. it was possible to rule out a work-induced intoxication, and n-nonacosane storage appeared to be accounted for ... | 1987 | 2960393 |
| a comparative study of the egg-laying behaviour and larval development of pieris rapae l. and p. brassicae l. on the same host plants. | pieris rapae and p. brassicae feed on the same host plants and have synchronized seasons. p. brassicae, whose larvae are twice the size of p. rapae, lays eggs in clusters of 40-100 eggs whereas p. rapae lays single eggs. in this paper we examine how egg clustering may be advantageous for p. brassicae. the larval development of each species was studied, and found not to differ significantly. p. brassicae larvae were observed to migrate from their host plant after defoliating it. a comparison of t ... | 1985 | 28311324 |
| increased green and yellow vegetable intake and lowered cancer deaths in an elderly population. | in a prospective cohort study of 1271 massachusetts residents 66 years of age or older, we examined the association between consumption of carotene-containing vegetables and subsequent five year mortality. dietary information was obtained by food frequency questionnaire in 1976. the relative risk of cancer mortality was examined within quintiles of green and yellow vegetable score (calculated from intake of carrots or squash, tomatoes, salads or leafy vegetables, dried fruits, fresh strawberries ... | 1985 | 3966422 |
| determination of triazamate in apples, peas and brussels sprouts using high-performance liquid chromatography with tandem mass spectrometry. | a rapid method was developed to allow the analysis of triazamate and the hydrolysis product triazamate acid in apples, peas and brussels sprouts. the procedure was based on acidified methanol extraction with quantification by liquid chromatography coupled with tandem mass spectrometry detection. the detection limit, based on the lowest calibration level, was 0.005 mg kg(-1). the method was validated at 0.05 and 0.01 mg kg(-1), and was used for screening of triazamate acid in the surveillance of ... | 2004 | 15204546 |
| [hydroxycinnamic acid esters in brassicaceous vegetables and garden cress]. | the esters of caffeic, p-coumaric and ferulic acid with glucose or quinic acid and sinapoylglucose were determined in cauliflower, kale, brussel sprouts, red, white, savoy and chinese cabbage and in garden cress by two different hplc methods with gradient elution. in addition the occurrence of sinapin (sinapoylcholin) was checked. the pattern of hydroxycinamic acid esters in the brassica species varied appreciably. in garden cress besides sinapin only sinapoylglucose was found. sinapoylglucose i ... | 1983 | 6613360 |
| the inheritance of node number and rate of node production in brussels sprouts. | the total vegetative node number, rate of node production and number of sprouts over 13 mm diameter were recorded for 10 f1 brussels sprout cultivars and 45 progenies derived by intercrossing and selfing them. significant differences, resulting from additive gene action, were found between the 10 cultivars and between their progenies for both characters. for total node number there was also evidence of dominant gene action. total node number and rate of node production were closely correlated as ... | 1981 | 24276384 |
| cruciferous vegetable consumption alters the metabolism of the dietary carcinogen 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine (phip) in humans. | consumption of red meat is associated with an increased risk of colorectal cancer, whereas cruciferous vegetable consumption reduces cancer risk. while the mechanisms remain to be determined, cruciferous vegetables may act by altering the metabolism of carcinogens present in cooked food, such as the heterocyclic amine 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine (phip). the aim of this study was to evaluate the effect of cruciferous vegetable consumption on the metabolism of phip in 20 non-sm ... | 2004 | 15073045 |
| [changes in weight of fresh and dried vegetables on cooking]. | the present study represents part of a more important work relative to normal food refuse and change of weight of varied food according to different ways of cooking. the study has been realized on vegetables and some fruits of frequent utilization in the population. it was accomplished by 25 voluntary housekeepers from paris and marseille during a whole year according to precise instructions about the method of weighings, every vegetable having to be weighed, three times at different intervals, ... | 1976 | 970838 |
| glucoraphanin and 4-hydroxyglucobrassicin contents in seeds of 59 cultivars of broccoli, raab, kohlrabi, radish, cauliflower, brussels sprouts, kale, and cabbage. | the importance of dietary sulforaphane in helping maintain good health continues to gain support within the health-care community and awareness among u.s. consumers. in addition to the traditional avenue for obtaining sulforaphane, namely, the consumption of appropriate cruciferous vegetables, other consumer products containing added glucoraphanin, the natural precursor to sulforaphane, are now appearing in the united states. crucifer seeds are a likely source for obtaining glucoraphanin, owing ... | 2004 | 14969551 |
| the use of folic acid for the prevention of neural tube defects and other congenital anomalies. | to provide information regarding the use of folic acid for the prevention of neural tube defects (ntds) and other congenital anomalies, in order that physicians, midwives, nurses, and other health-care workers can assist in the education of women in the preconception phase of their health care. option: folic acid supplementation is problematic, since 50% of pregnancies are unplanned and the health status of women may not be optimal. | 2003 | 14608448 |
| efficacy of steinernematid nematodes against three insect pests of crucifers in quebec. | steinernematid nematodes were evaluated against the three major cruciferous insect pests: the imported cabbageworm artogeia rapae, the diamondback moth plutella xylostella, and the cabbage looper trichoplusia ni. lc(50) values of s. carpocapsae all, s. feltiae uk, s. feltiae 27, and s. riobrave 335 were 18.2, 3.6, 5.7, and 8.3 on a. rapae l(2); 24.5, 2.3, 6.0, and 15.5 on p. xylostella l(3); and 10.1, 4.7, 9.5, and 7.8 on t. ni l(2), respectively. insect mortality from the nematode species and i ... | 2003 | 19262759 |
| an adenosine hydrolase from brussels sprouts. | | 1963 | 14085386 |
| [not available]. | | 1947 | 18910906 |
| relation of hydrophilic colloids to hardiness in cabbage, brussels sprouts, and alfalfa plants as shown by the dye adsorption test. | | 1933 | 16652832 |
| using a correction factor to correct for overreporting in a food-frequency questionnaire does not improve biomarker-assessed validity of estimates for fruit and vegetable consumption. | to correct for overreporting of fruit and vegetable (fv) consumption in a food-frequency questionnaire, summary questions about consumption of main fv groups are often used to calculate correction factors. this study compared the ability to rank people according to their fv intake of those summary questions and the sum of questions on individual fv items within categories, and of corrected or uncorrected estimates of specific sorts of fv. healthy middle-age women (n = 161) completed a food-frequ ... | 2003 | 12672945 |
| effect of chemopreventive compounds from brassica vegetables on nad(p)h:quinone reductase and induction of dna strand breaks in murine hepa1c1c7 cells. | we have compared the effects of aqueous extracts of cooked brussels sprouts, isolated glucosinolates and their breakdown products on the activity of quinone reductase [nadph:quinone-reductase] (qr) and on dna strand breaks induced by hydrogen peroxide in murine hepa1c1c7 cells. qr activity was not significantly altered after incubation of the cells with brussels sprouts extracts. however, some of the glucosinolates and in particular their myrosinase-catalysed hydrolysis products and the degradat ... | 2003 | 12615118 |
| effect of vegetables, tea, and soy on endogenous n-nitrosation, fecal ammonia, and fecal water genotoxicity during a high red meat diet in humans. | red meat increases colonic n-nitrosation, and this may explain the positive epidemiological relationship between red meat intake and colorectal cancer risk. vegetables, tea, and soy have been shown to block n-nitroso compound (noc) formation and are associated with protection against colorectal cancer. to determine whether these supplements affect fecal noc excretion during consumption of a high red meat (420 g/day) diet, 11 male volunteers were studied over a randomized series of 15-day dietary ... | 2002 | 12235653 |
| applying science to changing dietary patterns. | the intake of 400-600 g/d of fruits and vegetables is associated with reduced incidence of many common forms of cancer. these foods contain phytochemicals that can modulate gene expression to inhibit carcinogenesis via multiple pathways. many phytochemicals are colorful, providing an easy way to communicate increased diversity of fruits and vegetables to the public. red foods contain lycopene, the pigment in tomatoes, which is localized in the prostate gland and may be involved in maintaining pr ... | 2001 | 11694651 |
| the alpha-linolenic acid content of green vegetables commonly available in australia. | green vegetable consumption has long been considered to have health benefits mainly due to the vitamins, minerals and phytonutrients (such as vitamin c, folate, antioxidants etc) contained in a vegetable-rich diet. additionally, green vegetables are known to contain a relatively high proportion of omega-3 polyunsaturated fatty acids (pufas), primarily in the form of alpha-linolenic acid (18:3n-3). however, there are no data available on the fatty acid composition and concentration of green veget ... | 2001 | 11582857 |
| genetic taste markers and food preferences. | sensitivity to the bitter taste of 6-n-propylthiouracil (prop) is an inherited trait. although some people find prop to be extremely bitter, others cannot distinguish prop solutions from plain water. in a series of studies, greater prop sensitivity was linked with lower acceptability of other bitter compounds and with lower reported liking for some bitter foods. women, identified as "super-tasters" of prop, had lower acceptance scores for grapefruit juice, green tea, brussels sprouts, and some s ... | 2001 | 11259346 |
| quantitative determination of the glucosinolates sinigrin and progoitrin by specific antibody elisa assays in brussels sprouts. | glucosinolates from brussels sprout samples were extracted using an effective concentration of 2% phosphoric acid followed by a neutralization step and heat treatment for removal of inactivated protein. the (potentially) bitter glucosinolates sinigrin and progoitrin were found to be stable during this new extraction protocol. antisera, as raised against hemisuccinate-linked glucosinolate conjugates, were very specific in sandwich elisa assays for their corresponding substrates. the elisa assays ... | 1998 | 10554317 |
| effect of cruciferous vegetables on lung cancer in patients stratified by genetic status: a mendelian randomisation approach. | whether consumption of cruciferous vegetables protects against lung cancer is unclear, largely because of potential confounding factors. we therefore studied the role of cruciferous vegetables in lung cancer after stratifying by gstm1 and gstt1 status, two genes implicated in the elimination of isothiocyanates, the likely chemopreventative compound. in 2141 cases and 2168 controls, weekly consumption of cruciferous vegetables protected against lung cancer in those who were gstm1 null (odds ratio ... | 2015 | 16257343 |
| large scale determination of glucosinolates in brussels sprouts samples after degradation of endogenous glucose. | a method was developed for the determination of the glucosinolate content in glucose-rich samples of brassica vegetables such as brussels sprouts. glucose in the samples was enzymatically degraded by the enzyme glucose oxidase (god). the resulting hydrogen peroxide and the enzyme god were thereafter respectively dissociated and inactivated by a heat treatment at 100 degrees c. after the degradation of endogenous glucose the glucosinolates were converted into glucose and related metabolites with ... | 1999 | 10552411 |
| chemoprevention of breast cancer. | a critical question is, why do the european studies fail to confirm the us study? clearly, the answers are complex and uncertain. differences in power, age, risk, compliance, the use of ert, and follow-up in the european studies may all be relevant. the efficacy of tamoxifen in brca 1 or 2 carriers is an important issue; recent data have shown a dna repair defect in those with brca 1 gene alterations. this finding, coupled with the potential genotoxicity of tamoxifen, is of concern, but the nsab ... | 1999 | 10572559 |
| plant sterols in vegetables and fruits commonly consumed in sweden. | plant sterols are known to have serum cholesterol lowering effects. a high dietary intake might therefore have a positive impact on health. all food items of vegetable origin contain some amount of plant sterols. the aim of this study was to analyse the plant sterol content of vegetables and fruits commonly consumed in sweden, and to compare fresh and cooked samples of the same items. altogether 20 different vegetables and 14 fruits were analysed. all vegetables and fruits were purchased in two ... | 1999 | 10352947 |
| epidemiological studies on brassica vegetables and cancer risk. | this paper gives an overview of the epidemiological data concerning the cancer-preventive effect of brassica vegetables, including cabbage, kale, broccoli, brussels sprouts, and cauliflower. the protective effect of brassicas against cancer may be due to their relatively high content of glucosinolates. certain hydrolysis products of glucosinolates have shown anticarcinogenic properties. the results of 7 cohort studies and 87 case-control studies on the association between brassica consumption an ... | 1996 | 8877066 |
| effects of consumption of brussels sprouts on intestinal and lymphocytic glutathione s-transferases in humans. | a high intake of glucosinolate-containing cruciferous vegetables, such as brussels sprouts (brassica oleraceae), has been linked to a decreased cancer risk, but the underlying mechanism is still unclear. the aim of this study was to reveal possible modulating effects of consumption of brussels sprouts on duodenal, rectal and lymphocytic (i) glutathione s-transferase (gst) enzyme activity, (ii) gst isozyme levels and (iii) glutathione (gsh) content. ten healthy non-smoking volunteers were randoml ... | 1995 | 7554064 |
| effects of consumption of brussels sprouts on plasma and urinary glutathione s-transferase class-alpha and -pi in humans. | the effects of consumption of glucosinolate-containing brussels sprouts on plasma and urinary glutathione s-transferase (gst) class-alpha and -pi were investigated. five male and five female non-smoking volunteers were randomly assigned to two groups in a crossover design. five persons started on a glucosinolate-free diet (control period), while the other five consumed 300 g of cooked brussels sprouts per day, at the expense of 300 g of glucosinolate-free vegetables (sprouts period). dietary reg ... | 1995 | 7728980 |
| effects of different vegetables in mixed meals on glucose homeostasis and satiety. | different vegetables--carrots, peas, brussels sprouts and spinach--were added to a typical swedish lunch test meal in portions of 96-164 g. the test and the control meals without vegetables were balanced with respect to digestible carbohydrates (59.7 g) and energy (2000 kj, 475 kcal), and as far as possible also concerning protein and fat. the added vegetables contained 4.4 g dietary fibre. the meals were prepared by microwave heating and served in the morning after an overnight fast to 10 healt ... | 1993 | 8384548 |
| modification of carcinogen metabolism by indolylic autolysis products of brassica oleraceae. | cruciferous plant foods contain large quantities of secondary plant metabolites that have been shown to inhibit chemically induced carcinogenesis in animals. one mechanism by which these chemicals may inhibit carcinogenesis is through the induction of enzymes, such as cytochrome p-450-dependent monooxygenases, glutathione s-transferases (gst) or epoxide hydrolases (eh), which metabolize carcinogens to more polar and excretable forms. cruciferous vegetables of the brassica genus (e.g. brussels sp ... | 1991 | 1897390 |
| the effect of a diet rich in brussels sprouts on warfarin pharmacokinetics. | ten healthy subjects were given 20 mg of warfarin orally before, and after a daily intake of 400 g of brussels sprouts for 2 weeks. the brussels sprouts diet stimulated warfarin disposal as evidenced by a 29% increase in mean elimination rate constant, accompanied by a 27% increase in metabolic clearance rate and a 16% decrease in plasma auc. it is concluded that a high intake of brussels sprouts, a cruciferous vegetable, accelerates warfarin disposal, and thereby might contribute to less antico ... | 1988 | 3203715 |
| effect of brussels sprouts and cabbage on drug conjugation. | ten healthy subjects were fed three diets for 10 days each: a control diet, a cabbage and brussels sprouts--containing diet, and the control diet a second time. oxazepam was taken on day 7 and acetaminophen on day 10 of each dietary regimen. the test diet stimulated the metabolism of acetaminophen, at least in part by enhanced glucuronidation, as evidenced by a 16% decrease in mean plasma auc, a 17% increase in mean metabolic clearance rate, an increased ratio of acetaminophen glucuronide to ace ... | 1984 | 6692645 |
| [vitamin concentration in different varieties and grades of cabbage]. | examinations covered 8 varieties (28 grades) of cabbage for the content therein of c, b6 vitamins, beta-carotene, thiamine, riboflavin, niacin and folacin. all the cabbage specimens were analyzed right after picking. in 2 grades of the cabbage vitamins were determined after picking and repeatedly after storage (9 months in a vegetable storehous). it was found that there existed a significant difference in the quantitative content of vitamins between individual varieties of cabbage. the proportio ... | 2013 | 982952 |
| effects of dietary constituents on the metabolism of chemical carcinogens. | dietary constituents of 2 types have been shown to affect the metabolism of chemical carcinogens by the microsomal mixed-function oxidase system. naturally occurring inducers of increased activity of this system are present in plants. cruciferous vegetables including brussels sprouts, cabbage, and cauliflower are relatively potent in this regard. from these vegetables, three indoles with inducing activity have been identified. these are indole-3-acetonitrile, indole-3-carbinol, and 3,3'-diindoly ... | 1975 | 1104144 |
| pesticide residues in foodstuffs in great britain. vii. demeton-methyl and dimethoate residues in brussels sprouts, lettuce, green peas and french beans, potatoes and strawberries. | | 1968 | 5678489 |
| the mineral composition of brussels sprouts. | | 1966 | 5911855 |
| review article: omeprazole and the cytochrome p450 system. | enzymes of the cytochrome p450 superfamily play a key role in xenobiotic metabolism. their properties and significance are discussed with particular reference to interactions with the h+,k(+)-atpase blocker, omeprazole. such interactions include both inhibitory (subfamily 2c) and inducing effects (subfamily 1a). delayed metabolic elimination of diazepam, warfarin, carbamazepin and phenytoin is probably due to omeprazole competition for the concerned isoform of subfamily 2c; however, these effect ... | 1995 | 7766737 |
| [omeprazole and the cytochrome p450 system of the liver]. | enzymes of the cytochrome p450 family play a key role in xenobiotic and thus drug metabolism. the h+,k(+)-atpase blocker, omeprazole, has been reported to inhibit (subfamily p450iic) or induce (p450ia) this system. the slower metabolic elimination of diazepam, warfarin und phenytoin is probably due to omeprazole competition for p450iic; however, this effect was rather negligible in magnitude and not reproducible in each case. also induction of p450ia was only minor; it resulted in no (theophylli ... | 1993 | 8412467 |