Publications
| Title | Abstract | Year Filter | PMID(sorted ascending) Filter |
|---|
| ontogenetical and histochemical studies on the translator apparatus in calotropis procera r. br. i. the retinaculum. | translator apparatus consists of 2 parts--the corpusculum, which is attached to the margin of the stigmatic head between the anthers, and a pair of arms by which the corpusculum is attached to the pollinia of the adjacent anther halves. retinaculum spans the lateral blade of the corpusculum to the acellular beak of the pollinium. ontogenetically, it is the secretory product of the stigma along the secondary stigmatic groove. histochemically, it is composed of lipid, lignin, cutin and a little am ... | 1978 | 411312 |
| the effects of calotropis procera on small ruminants. i. effects of feeding sheep with the plant. | 1979 | 457943 | |
| the effects of calotropis procera on small ruminants. ii. effects of administration of the latex to sheep and goats. | 1979 | 457944 | |
| effect of ak calotropis procera (ait.) r. br. flower extract on testicular function of the indian desert male gerbil meriones hurrianae jerdon: a biochemical & histological study. | 1979 | 544463 | |
| seed germination as a thermobiological problem. | thermal effects on seed germination are considered through the changes brought about by temperature in the germination capacity, in the germination rate, and in the distribution of the relative frequency of germination along the incubation times. a number of questions of general thermobiological interest are thus raised, entailing the need of an analysis of the temperature dependence of the seed germination rate. a treatment of these rates by the activation-energy approach cannot be general, for ... | 1978 | 756055 |
| calotropis procera (sodom apple) latex keratoconjunctivitis. | 1977 | 924767 | |
| calotropis procera: feed potential for arid zones. | 1992 | 1529520 | |
| pharmacological studies on aerial parts of calotropis procera. | the decoction of the aerial part of calotropis procera is commonly used in saudi arabian traditional medicine for the treatment of variety of diseases including fever, joint pain, muscular spasm and constipation. the present investigation was undertaken to confirm its claimed activity in traditional medicine. the ethanol extract of the plant was tested on laboratory animals for its antipyretic, analgesic, anti-inflammatory, antibacterial, purgative and muscle relaxant activities. the results of ... | 1991 | 1767794 |
| preliminary studies on the antiinflammatory and analgesic activities of calotropis procera root extract. | a chloroform-soluble fraction from calotropis procera roots showed significant dose-related antiinflammatory activity in rats using the pharmacologic models of carrageenin-induced pedal oedema, cotton pellet granuloma and formaldehyde-induced arthritis. in addition, significant analgesic potential was demonstrated using acetic acid-induced writhing in mice. | 1991 | 2056759 |
| the activities of drug-metabolizing enzymes in goats treated orally with the latex of calotropis procera and the influence of dieldrin pretreatment. | the effects of oral administration of different doses of the latex of calotropis procera on the activities of drug-metabolizing enzymes in the liver, kidneys and duodenal mucosa of nubian goats were investigated. lesions and changes in total plasma protein concentration and in the activities of plasma sorbitol dehydrogenase (sd), glutamate dehydrogenase (gd) and aspartate aminotransferase (ast) were studied. the daily oral administration of the latex at dose rates of 0.4 and 0.8 ml per kg for 7 ... | 1991 | 2061426 |
| naturally occurring cardiac glycosides. | cardiac glycoside poisoning from the ingestion of plants, particularly of oleanders, occurs with reasonable frequency in tropical and subtropical areas. we have assessed a variety of plant specimens for their cardiac glycoside content by means of radioimmunoassays with antibodies that differ in their specificity for cardiac glycosides. significant amounts of immunoreactive cardiac glycoside were found to be present in the ornamental shrubs: yellow oleander (thevetia peruviana); oleander (nerium ... | 1986 | 3086679 |
| the toxicity of indian calotropis procera rbr latex in the black rat, rattus rattus linn. | toxicity studies with latex of calotropis procera rbr were conducted in the black rat, rattus rattus. the latex was fed through bait prepared from wheat flour, ground nut oil and sugar at concentrations of 5, 7.5 or 10% (w/w). the bait was fed up to mortality and for a maximum of 10 days. the signs produced were passivity, sluggishness, sedation, dyspnea, weakness, reduction in weight, anorexia, diarhhea, hematuria, bleeding from nose, eyes and anus, eye lens opacity, mild tetanic convulsions, c ... | 1988 | 3176304 |
| ethnopharmacology of calotropis procera flowers. | an ethanolic extract of the flowers of calotropis procera was investigated for anti-inflammatory, antipyretic, analgesic and antimicrobial activities. the plant extract reduced the paw swelling induced by carrageenan by 37%, fever in rats by 40% and showed some weak effect in rats on the writhing induced by acetic acid. the growth of both gram-positive and gram-negative bacteria was significantly inhibited. a dose-dependent effect on prostaglandin release was also observed. | 1988 | 3259655 |
| [toxicity of calotropis procera. effect of a calotropis procera-based feed on embryonic and neonatal mortality in laboratory mice]. | 1985 | 3837927 | |
| antagonism between plant growth regulators in pollen tube elongation of calotropis procera. | 1974 | 4833670 | |
| [glycosides of calotropis procera r.br. glycosides and aglycones. 320]. | 1969 | 5361916 | |
| feeding rubberbush (calotropis procera) to cattle and sheep. | 1984 | 6497815 | |
| allergic contact dermatitis due to the plant calotropis procera (vern: ak). a case report. | 1984 | 6545244 | |
| nutrient and cardenolide composition of unextracted and solvent-extracted calotropis procera. | 2008 | 6886206 | |
| ayurvedic herbal drugs with possible cytostatic activity. | ayurveda is considered to be the traditional science of health in india and is based on the principle of subjectivity. all matter is composed of five basic elements, which can be perceived by the five sense organs. all food and drugs are classified according to their pharmacological properties, which are derived from these five elements. to investigate which ayurvedic plants might have cytostatic activity, an ayurvedic model for the pathogenesis of cancer was made. based on this, selection crite ... | 1995 | 7500639 |
| [traditional therapy of dracunculiasis in the state of bauchi - nigeria]. | traditional medicinal treatments of guinea worm being applied in various parts of bauchi state were investigated. extracts of leaves of a number of plants were universally applied topically. users perceived relief of pain and accelerated expulsion of worms and healing process. in particular, tamarindus indica, adansonia digitata, calotropis procera, ziziphus jaozeiro and moringa olifera are known in nature to have relevant medicinal properties especially lessening of inflammation, relief of pain ... | 1993 | 7758381 |
| anti-inflammatory activity of the latex of calotropis procera. | the anti-inflammatory property of the latex of calotropis procera was studied on carrageenin- and formalin-induced rat paw oedema model. a single dose of the aqueous suspension of the dried latex was effective to a significant level against the acute inflammatory response. | 1994 | 7853863 |
| [senegalese pharmacopoeia: study of acute toxicity and antitussive activity of calotropis procera ait (asclepiadaceae)]. | we confirmed the innocuity of different extracts (leaves and stem bark) of calotropis procera (asclepiadaceae), a plant widely used in asian and west african traditional therapy in dermatological and bronchal affections. we proved the against cough activity of the aqueous stem bark extract after administration, per os, upon bronchal irritation by ammoniac on guinea pig. | 1993 | 7882852 |
| insecticidal activity of calotropis procera extracts of the flesh fly, sarcophaga haemorrhoidalis fallen. | the insecticidal activity, expressed by ld50 values, of acetone, ethanol, petroleum ether and water extracts of calotropis procera leaves against the flesh fly, sarcophaga haemorrhoidalis fallen was evaluated in the laboratory. based on ld50 values, ethanol extract was nearly 1.7, 1.3 and 1.3 times more toxic to larvae than water, petroleum ether and acetone extracts, respectively. it was 1.9, 1.4 and 1.2 times more toxic to pupae than water, acetone and petroleum ether extracts, respectively. i ... | 1997 | 9257990 |
| studies on the possible mechanism of the gastric mucosal protection by calotropis procera--involvement of 5-lipoxygenase pathway. | the role of chloroform fraction of calotropis procera root extract on different experimental ulcer models in rats was investigated. the extract demonstrated significant anti-ulcer activity against aspirin, indomethacin, ethanol, indomethacin + ethanol, or stress-induced ulcerations. significant inhibition of gastric secretory volume and total acidity in pylorus ligated rats were observed to occur with the extract. it was also observed that the root extract significantly inhibited arachidonic aci ... | 1998 | 9523189 |
| studies on laticiferous plants: toxic effects in goats of calotropis procera latex given by different routes of administration. | the effects on goats of calotropis procera latex given by different routes of administration were investigated. the administration of latex at 1 ml/kg body weight via the oral route or at 0.005 ml/kg body weight/day via the intravenous or intraperitoneal route caused death of the goats between 20 minutes and 4 days. when the small dose of latex (0.005 ml/kg body weight/day) was given by the oral route or intramuscular route no death among the goats occurred. nervous signs, frequent urination, fr ... | 1998 | 9857566 |
| [poisoning with toxic plants in curacao in 1766]. | in the spring of 1766 a black supervisor in curaçao was the victim of attempted poisoning by a black practitioner or curador, engaged by two persons caught stealing by the supervisor. data on the case were preserved in a letter from the curaçao director to the managers of the west-indian company in amsterdam. in retrospect, the symptoms of the intoxication indicate that a similar mixture of toxic plants was used as described in 890 a.d. by the arabic medical writer wahshiya in his 'book of poiso ... | 1998 | 10065248 |
| evaluation of in vitro schizontocidal activity of plant parts of calotropis procera--an ethnobotanical approach. | calotropis procera (ait.) r.br. commonly known, as 'arka' is a popular medicinal plant found throughout the tropics of asia and africa and is used in many traditional systems of medicine. important factors of the various parts of this plant have been widely reported. good record keeping of subjective and objectively recorded cures by practitioners of traditional medicinal system will help in the establishment of the use of c. procera as an antimalarial plant. it has been attempted to see the eff ... | 1999 | 10624866 |
| healing potential of calotropis procera on dermal wounds in guinea pigs. | calotropis procera (asclepiadaceae) is a well known plant in the ayurvedic system of medicine. based on its traditional use this plant was selected for evaluation of its wound healing potential. for this purpose four full thickness excisional wounds of 8.0 mm diameter were inflicted on the back of guinea pigs. topical application of 20 microl of 1.0% sterile solution of the latex of c. procera twice daily was followed for 7 days. the latex significantly augmented the healing process by markedly ... | 1999 | 10624886 |
| screening of antibacterial and antiparasitic activities of six moroccan medicinal plants. | the extracts of six plants selected on the basis of folk-medicine reports were examined for their antibacterial effects against eight pathogenic bacteria. the results showed that n-butanol extract of calotropis procera proved to be the most effective against the bacteria tested using the paper disc diffusion method. the antiprotozoal activity was also examined and showed that ethyl ether extract of sium nodiflorum exhibits a parasiticidal effect against trichomonas intestinalis and vaginalis. | 1999 | 10709454 |
| evaluation of some moroccan medicinal plant extracts for larvicidal activity. | the larvicidal properties of 16 extracts of four moroccan medicinal plants: calotropis procera (wild.), cotula cinerea (l.), solanum sodomaeum (l.) and solanum elaeagnifolium (cav.) were tested against anopheles labranchiae mosquito larvae. among the extracts tested, nine exhibited high larvicidal activity with lc(50) (24 h) ranging from 28 to 325 ppm. | 2000 | 11025168 |
| preliminary studies on the analgesic activity of latex of calotropris procera. | in this study we have evaluated the analgesic activity of dry latex (dl) of calotropis procera. a single oral dose of dl ranging from 165 to 830 mg/kg produced a significant dose dependent analgesic effect against acetic acid induced writhings. the effect of dl at a dose of 415 mg/kg was more pronounced as compared to a 100 mg/kg oral dose of aspirin. on the other hand dl (830 mg/kg) produced marginal analgesia in a tail-flick model which was comparable to aspirin. the analgesic effect of dl was ... | 2000 | 11025170 |
| screening of yemeni medicinal plants for antibacterial and cytotoxic activities. | ethanolic extracts of 20 selected plant species used by yemeni traditional healers to treat infectious diseases were screened for their antibacterial activity against both gram-positive and gram-negative bacteria, as well as for cytotoxic activity. fourteen of the ethanolic extracts showed variable degrees of antibacterial activity. the active ethanolic extracts were partitioned between ethyl acetate and water for a first separation. the ethyl acetate extract of lawsonia inermis was found to be ... | 2001 | 11167035 |
| a preliminary study on the anthelmintic activity of calotropis procera latex against haemonchus contortus infection in najdi sheep. | the anthelmintic activity of calotropis procera latex was investigated in sheep that had been infected with single oral doses of 12000 infective haemonchus contortus larvae. inappetence, dullness, erosive abomasitis, decreased haemoglobin concentration and increased eosinophils were the main features of haemonchosis in the sheep. in the sheep treated with single oral doses of 0.01 ml or 0.02 ml/kg body weight of c. procera latex, egg production was significantly reduced, but not completely suppr ... | 2001 | 11214673 |
| norditerpenic ester and pentacyclic triterpenoids from root bark of calotropis procera (ait) r. br. | a new norditerpenyl ester, named calotropterpenyl ester, and two unknown pentacyclic triterpenoids, namely calotropursenyl acetate and calotropfriedelenyl acetate have been isolated from the root bark of calotropis procera. their structures have been established as 6,10,14-trimethylpentadec-6-enyl-2',4',8',12',16'-pentamethyl nonadecane ester, urs-12,19(29)-diene-3 beta-yl acetate and friedelin-1-ene-3 beta-yl acetate, respectively, on the basis of spectral data analyses and chemical reactions. | 2001 | 11234349 |
| inflammation induced by latex of calotropis procera--a new model to evaluate anti-inflammatory drugs. | latex of calotropis procera was studied for its inflammatory reactions using pedal oedema and air pouch models of inflammation in rats. subcutaneous injection of aqueous solution (0.1 ml of 1%) of dry latex (dl) into the plantar surface of paw produced significant inflammation. maximum inflammatory response was obtained 1 h after the injection and was maintained for a further 1 h. the inflammatory response was accompanied by an increase in vascular permeability that reached its maximum within 15 ... | 2000 | 11257487 |
| in vitro hemolysis of human erythrocytes -- by plant extracts with antiplasmodial activity. | human erythrocytes were exposed in a dose dependent manner to various ethanolic plant extracts, and fractions obtained from plant parts of calotropis procera (ait.) r. br. and the gum--oleo resin of commiphora wightii (arnott.) bhand. these have been screened for in vitro schizontocidal activity and graded with respect to their 50% inhibitory concentration (ic(50)) derived from the twofold serial dilution of the dose range 0.0625--2 mg/ml. an attempt had been made to relate their antiplasmodial ... | 2001 | 11274824 |
| antibacterial activity of some moroccan medicinal plants. | the extracts of 12 plants selected on the basis of the folk-medicine reports were examined for their antibacterial effects against eight pathogenic bacteria. the n-butanol extract of calotropis procera flowers and the aqueous extract of eugenia caryophyllata proved to be the most effective against the bacteria tested. | 2001 | 11351362 |
| anti-diarrhoeal activity of the latex of calotropis procera. | the dry latex (dl) of calotropis procera (asclepiadaceae), a potent anti-inflammatory agent has been evaluated for anti-diarrhoeal activity. like atropine and phenylbutazone (pbz), a single oral dose of dl (500 mg/kg) produced a significant decrease in frequency of defecation, severity of diarrhoea and afforded protection from diarrhoea in 80% rats treated with castor oil. to understand the mechanism of its anti-diarrhoeal activity, we further evaluated its effect on intestinal transit, castor o ... | 2001 | 11378292 |
| in-vitro schizonticidal screening of calotropis procera. | following an ethnobotanical approach, the ethanol extracts of calotropis procera leaves, stems, roots, flowers and buds have been screened in vitro for antimalarial activity against chloroquine (cq)-sensitive and cq-resistant plasmodium falciparum strains. | 2000 | 11449477 |
| effects of calotropis procera on oestrous cycle and on oestrogenic functionality in rats. | effects of ethanolic and aqueous extracts of calotropis procera (ait.) r.br. roots, have been studied on oestrous cycle and on some parameters of oestrogenic functionality in rats. both extracts have been shown to interrupt the normal oestrous cycle in 60 and 80%, respectively, of rats treated. the rats exhibited prolonged dioestrous stage of the oestrous cycle with consequent temporary inhibition of ovulation. the contemporary administration of commercial oestro-progestinic preparation exhibite ... | 2001 | 11482761 |
| the antipyretic activity of some moroccan medicinal plants. | the antipyretic activity of different extracts from calotropis procera, cotula cinerea and zygophyllum gaetulum was investigated experimentally in rats. the antipyretic effect was retained in all extracts tested and was comparable to that of acetylsalicylic acid used as the standard drug. | 2002 | 11933154 |
| preliminary study on antifertility activity of calotropis procera roots in female rats. | the effect of ethanolic extract of the roots of calotropis procera has been studied in albino rats to explore its antifertility and hormonal activities. a strong antiimplantation (inhibition 100%) and uterotropic activity was observed at the dose level of 250 mg/kg (1/4 of ld(50)). no antiestrogenic activity could be detected. | 2002 | 11978424 |
| organic carbonate from calotropis procera leaves. | the leaves of calotropis procera yielded an organic carbonate (1), along with stigmasterol and beta-sitosterol, identified by spectroscopic methods. | 2002 | 12048023 |
| current status of plant products reported to inhibit sperm. | this report reviews research on plant-derived agents that prevent sperm production if taken orally by the male or that incapacitate or kill sperm on contact if used vaginally by the female. it would be of great value to develop fertility inhibitors that are totally selective for reproductive systems and enzymes, and there is a possibility that a plant-derived drug may have this effect. plants that have been studied for their fertility inhibiting effects in the male include: aristolochia indica l ... | 1982 | 12179631 |
| control of musca domestica third instar larvae by the latex of calotropis procera (family: asclepiadaceae). | calotropis procera (family: asclepiadaceae) is known to contain alkaloids, steroids and resinous substance. different concentrations of its latex were topically applied to the 3rd stage larvae of musca domestica. a dose of 3 ul (5% of the latex) killed and partially digested the larvae in three hours. the effect of this latex is most probably enzymatic in nature. no doubt, the shift to plant extracts in controlling insect-vectors or pests in general, pave the way to a health environment. | 2001 | 12557934 |
| procerain, a stable cysteine protease from the latex of calotropis procera. | a protease was purified to homogeneity from the latex of medicinal plant calotropis procera (family-asclepiadaceae). the molecular mass and isoelectric point of the enzyme are 28.8 kda and 9.32, respectively. hydrolysis of azoalbumin by the enzyme was optimal in the range of ph 7.0-9.0 and temperature 55-60 degree c. the enzyme hydrolyses denatured natural substrates like casein, azoalbumin, and azocasein with high specific activity. proteolytic and amidolytic activities of the enzyme were activ ... | 2003 | 12591258 |
| calotropis procera (sodom apple)--a potential material for enzyme purification. | a simple method based on precipitation with calotropis procera latex was developed for the purification of crude enzyme from fermentation broth. c. procera latex (10(-2) dilution) clarified and concentrated the crude amylase of aspergillus oryzae 4-fold with 97% recovery of the initial amylase activity in the filtrate in a single step operation. the latex was stable at ph < or = 4.5 and there was no significant difference (p < or = 0.05) in the purification potential of the latex at 4 and 28 deg ... | 2003 | 12733587 |
| the latex of calotropis procera (family: asclepiadeceae), a new substance having an ascaricidal effect in-vitro. | 1959 | 14425779 | |
| differences in the unfolding of procerain induced by ph, guanidine hydrochloride, urea, and temperature. | the structural and functional aspects along with equilibrium unfolding of procerain, a cysteine protease from calotropis procera, were studied in solution. the energetic parameters and conformational stability of procerain in different states were also estimated and interpreted. procerain belongs to the alpha + beta class of proteins. at ph 2.0, procerain exists in a partially unfolded state with characteristics of a molten globule-like state, and the protein is predominantly a beta-sheet confor ... | 2003 | 14567690 |
| acaricidal effects of cardiac glycosides, azadirachtin and neem oil against the camel tick, hyalomma dromedarii (acari: ixodidae). | the cardiac glycoside, digitoxin, from digitalis purpurea l (scrophulariaceae), a cardiac glycosidal (cardenolide) extract from calotropis procera (ait) r br (asclepiadaceae), azadirachtin and neem oil from azadirachta indica a juss (meliaceae) were tested for their effects against larvae and adult stages of the camel tick, hyalomma dromedarii koch (acari: ixodidae). the contact lc50 values of the first three materials against adults were 4.08, 9.63 and >40.7 microg cm(-2), respectively, whereas ... | 2003 | 14620053 |
| histamine mediates the pro-inflammatory effect of latex of calotropis procera in rats. | introduction: calotropis procera is known to produce contact dermatitis and the latex of this plant produces intense inflammation when injected locally. however, the precise mode of its pro-inflammatory effect is not known. in present study we have pharmacologically characterized the inflammation induced by latex of c. procera in a rat paw edema model and determined the role of histamine in latex-induced inflammation. | 2003 | 14760937 |
| chemical constituents and energy content of some latex bearing plants. | the latex bearing plants plumeria alba, calotropis procera, euphorbia nerrifolia, nerium indicum and mimusops elengi were evaluated as potential renewable sources of energy and chemicals. plant parts (leaf, stem, bark) and also whole plants were analyzed for elemental composition, oil, polyphenol, hydrocarbons, crude protein, alpha-cellulose, lignin and ash. the dry biomass yields were between 4.47 and 13.74 kg/plant. the carbon contents in whole plants varied from 38.5% to 44.9%, while hydrogen ... | 2004 | 14766154 |
| biochemical aspects (antioxidants) for development of tolerance in plants growing at different low levels of ambient air pollutants. | the role of antioxidants, which are thought to scavenge the oxygen-free radicals in plants exposed to relatively low concentrations of ambient air pollutants for long durations, was studied for a year. increases were observed in superoxide dismutase peroxidase activity, sulphate and leaf area to dry weight ratio, and decreases in stomatal conductance, ascorbic acid, protein content and total lipids, as a general response of all the plants in the polluted area. the results indicate that high pero ... | 1990 | 15092307 |
| effect of calotropis procera latex on isoproterenol induced myocardial infarction in albino rats. | the alcoholic extract of the latex obtained from calotropis procera (asclepidaceae) was evaluated for protection against isoproterenol (20 mg/100 g body wt., s.c.)-induced myocardial infarction in albino rats. the heart damage induced by isoproterenol was indicated by elevated levels of the marker enzymes such as creatine kinase-isoenzyme (ck-mb), lactate dehydrogenase (ldh), serum glutamate oxaloacetic transaminase (sgot) and serum glutamate pyruvate transaminase (sgpt) in serum with increased ... | 2004 | 15185846 |
| involvement of prostaglandins in inflammation induced by latex of calotropis procera. | the aerial parts of the plant calotropis procera produce milky white latex that causes inflammation of the skin and mucous membranes. prostaglandins are one of the mediators released in an inflammatory response following induction of cyclooxygenase (cox). in the present study, we have evaluated the role of prostaglandins in inflammatory response elicited by the latex of c. procera. | 2004 | 15223605 |
| effect of anti-inflammatory drugs on pleurisy induced by latex of calotropis procera in rats. | in present study, we have characterized the inflammation induced by latex of calotropis procera in the rat pleurisy model and evaluated the effect of various inhibitors of inflammatory mediators. injection of dried latex (dl) into the pleural cavity elicited an acute inflammatory response characterized by protein rich fluid accumulation and leucocyte (polymorphonuclear cells, and mononuclear cells) infiltration in the pleural cavity. the peak inflammatory response was obtained at 6h when the flu ... | 2004 | 15225678 |
| in vivo and in vitro effect of latex of calotropis procera on gastrointestinal smooth muscles. | the present study was carried out to evaluate the effect of dry latex (dl) of calotropis procera on smooth muscles of gastrointestinal tract. oral administration of dl to rats (50-1000 mg/kg) produced a dose-dependent decrease in intestinal transit along with a decrease in intestinal content as compared to control group. at lower doses dl produced dose-dependent contractions of gastrointestinal smooth muscles in vitro (rabbit ileum and fundus of rat stomach) that was followed by desensitization ... | 2004 | 15234780 |
| anti-inflammatory effect of the latex from calotropis procera in three different experimental models: peritonitis, paw edema and hemorrhagic cystitis. | latex from calotropis procera is widely used in folk medicine as a rich source of biologically active compounds capable of promoting diverse benefits such as control of dermal fungal infections, antimicrobial activities and pain relief among other useful properties. the aim of this work was to characterize the anti-inflammatory effect of a non-dialysable protein fraction recovered from the rubber-free latex using three different experimental models when administrated intravenously. in vivo neutr ... | 2004 | 15643548 |
| calotropis procera (ushaar) keratitis. | to report a case of permanent endothelial cell injury after intracorneal penetration of milky latex from calotropis procera (ushaar). | 2005 | 15652855 |
| identification of a novel cardenolide (2''-oxovoruscharin) from calotropis procera and the hemisynthesis of novel derivatives displaying potent in vitro antitumor activities and high in vivo tolerance: structure-activity relationship analyses. | analysis of the methanolic extract of calotropis procera root barks enabled the identification of a novel cardenolide (2''-oxovoruscharin) to be made. of the 27 compounds that we hemisynthesized, one (23) exhibited a very interesting profile with respect to its hemisynthetic chemical yield, its in vitro antitumor activity, its in vitro inhibitory influence on the na+/k+-atpase activity, and its in vivo tolerance. compound 23 displayed in vitro antitumor activity on a panel of 57 human cancer cel ... | 2005 | 15689169 |
| in vitro spasmolytic effect of aqueous extract of calotropis procera on guinea-pig trachea smooth muscle chain. | the aqueous extract of calotropis procera was evaluated for its spasmolytic effect using in vitro trachea smooth muscle chain of guinea-pig. the extract (50, 100 and 200 microg/ml) showed a dose-dependent relaxant activity probably exhibited through the direct relaxant action on the smooth muscle. | 2005 | 15752643 |
| antinociceptive activity of calotropis procera latex in mice. | this work evaluated the antinociceptive effect of proteins from the calotropis procera (asclepiadaceae) latex using three different experimental models of nociception in mice. the latex protein fraction administered intraperitoneally in male mice at the doses of 12.5, 25 and 50 mg/kg showed the antinociceptive effect in a dose dependent manner compared to the respective controls in all assays. inhibitions of the acetic acid-induced abdominal constrictions were observed at the doses of 12.5 (67.9 ... | 2005 | 15848031 |
| interleukin-1beta inhibits paw oedema induced by local administration of latex of calotropis procera extracts. | interleukin-1beta (il-1beta), a pro-inflammatory cytokine, has been reported to exhibit anti-inflammatory properties in the carrageenan-induced paw oedema model. in the present study, we have evaluated the anti-inflammatory activity of il-1beta against inflammation induced by local administration of the methanol extract of dried latex of calotropis procera (medl) and compared it with that against carrageenan. the anti-inflammatory activity of standard anti-inflammatory drugs, phenylbutazone (pbz ... | 2004 | 15901416 |
| antioxidant and protective effect of latex of calotropis procera against alloxan-induced diabetes in rats. | in the present study, dry latex (dl) of calotropis procera possessing potent anti-inflammatory activity was evaluated for its antioxidant and anti-hyperglycemic effects against alloxan-induced diabetes in rats. daily oral administration of dl at 100 and 400 mg/kg doses produced a dose-dependent decrease in the blood glucose and increase in the hepatic glycogen content. dl also prevented the loss of body weight in diabetic rats and brought down the daily water consumption to values comparable to ... | 2005 | 16054794 |
| anthelmintic activity of calotropis procera (ait.) ait. f. flowers in sheep. | the anthelmintic activity of calotropis (c.) procera flowers in comparison with levamisole was evaluated through in vitro and in vivo studies. in vitro studies revealed anthelmintic effects (p<0.05) of crude aqueous (cae) and crude methanolic extracts (cme) of calotropis procera flowers on live haemonchus (h.) contortus as evident from their mortality or temporary paralysis. for in vivo studies, calotropis procera flowers were administered as crude powder (cp), cae and cme to sheep naturally inf ... | 2005 | 16085379 |
| calotropis procera latex-induced inflammatory hyperalgesia--effect of antiinflammatory drugs. | the milky white latex of plant calotropis procera produces inflammation of the skin and mucous membranes on accidental exposure. it produces edema on local administration due to the release of histamine and prostaglandins and is associated with hyperalgesia. in the present study we have evaluated the antiedematous and analgesic activity of antiinflammatory drugs against inflammatory response induced by dried latex (dl) of c procera in rat paw edema model. an aqueous extract of dl of c procera wa ... | 2005 | 16192671 |
| antiinflammatory efficacy of extracts of latex of calotropis procera against different mediators of inflammation. | the latex of the plant calotropis procera has been reported to exhibit potent antiinflammatory activity against carrageenin and formalin that are known to release various mediators. in the present study, we have evaluated the efficacy of extracts prepared from the latex of c procera against inflammation induced by histamine, serotonin, compound 48/80, bradykinin (bk), and prostaglandin e2 (pge2) in the rat paw oedema model. the paw oedema was induced by the subplantar injection of various inflam ... | 2005 | 16192673 |
| inhibition of calotropis procera latex-induced inflammatory hyperalgesia by oxytocin and melatonin. | the latex of the wild growing plant calotropis procera produces inflammation of the skin and mucous membranes upon accidental exposure. on local administration it elicits an intense inflammatory response due to the release of histamine and prostaglandins that is associated with hyperalgesia. in the present study we have evaluated the anti-inflammatory and antinociceptive activity of oxytocin and melatonin against rat paw edema induced by dried latex (dl) of c procera and compared it with that ag ... | 2005 | 16489256 |
| latex proteins from the plant calotropis procera are partially digested upon in vitro enzymatic action and are not immunologically detected in fecal material. | soluble proteins from the latex of calotropis procera (lp) were investigated in vitro and in vivo for digestibility as the latex has previously been shown to produce considerable toxic effects on animals. the latex is also an important biologically active compound that displays antiinflammatory and antidiarrhea properties. the proteins were digested by the action of trypsin, pepsin or chemotrypsin as revealed by gel filtration and sds-page analysis. furthermore, the full lp digestion was easily ... | 2006 | 16581200 |
| anticancer and cytotoxic properties of the latex of calotropis procera in a transgenic mouse model of hepatocellular carcinoma. | to evaluate the anticancer property of the dried latex (dl) of calotropis procera, a tropical medicinal plant, in the x15-myc transgenic mouse model of hepatocellular carcinoma and to elucidate its mechanism of action in cell culture. | 2006 | 16688796 |
| laboratory study on larvicidal properties of leaf extract of calotropis procera (family-asclepiadaceae) against mosquito larvae. | fresh leaf extract of milkweed (calotropis procera) showed larvicidal properties against mosquito larvae of anopheles stephensi, culex quinquefasciatus and aedes aegypti. methanolic extracts of the same plant were, however, more effective as larvicide. c. procera is a weed growing in uncultivated soils as well as in dry, arid zones in indian subcontinent throughout the year. the results of this study suggest the utility of milkweed as potential technology for control of mosquito larvae. | 2005 | 16749273 |
| a comparative study on the efficacy of rofecoxib in monoarticular arthritis induced by latex of calotropis procera and freund's complete adjuvant. | the role of prostaglandins in calotropis procera latex induced inflammation and hyperalgesia has been well established. the acute inflammation induced by the dried latex (dl) of this plant could be effectively ameliorated by standard anti-inflammatory drugs. in present study we have evaluated the efficacy of rofecoxib, a cox-2 inhibitor in monoarthritis induced by intra-articular injection of dl and compared it with that against freund's complete adjuvant (fca). dl and fca were injected into the ... | 2006 | 16835708 |
| effect of organic solvents on the molten globule state of procerain: beta-sheet to alpha-helix switchover in presence of trifluoroethanol. | the effect of methanol and trifluoroethanol (tfe) on the structure and folding of molten globule state of procerain, a cysteine protease from calotropis procera, was studied by circular dichroism spectroscopy. the magnitude of ellipticity at 215 nm, as a measure of beta-sheet content, is dependent on the concentration of the tfe. interestingly, a switch over from the beta-sheet structure of the molten globule state to alpha-helix was observed at 60% tfe and the ellipticity at 222 nm increased as ... | 2006 | 16842106 |
| evaluation of cytotoxic potential of latex of calotropis procera and podophyllotoxin in allium cepa root model. | in the present study we have utilized the allium cepa root tip meristem model to evaluate the cytotoxic and anti-mitotic activities of latex of calotropis procera (dl) and podophyllotoxin. standard cytotoxic drug cyclophosphamide and non-cytotoxic drugs cyprohcptadine and aspirin served as controls. like cyclophosphamide, both dl and podophyllotoxin significantly inhibited the growth of roots and mitotic activity in a dose-dependent manner. however, podophyllotoxin was more potent in this regard ... | 2006 | 16845823 |
| phytoextraction capacity of the plants growing on tannery sludge dumping sites. | the study was undertaken to assess the phytoremediation potential of four plants (sida acuta, ricinus communis, calotropis procera, cassia fistula) growing at a tannery sludge disposal site. results showed that maximum amount of k, fe and ni was associated with residual fraction, whereas, zn, mn, cr, pb, cd and co was found in fe-mn oxide fraction. cu and na were mostly associated with organic matter and carbonate fraction, respectively. the results demonstrated that the levels of accumulation o ... | 2007 | 16973356 |
| latex constituents from calotropis procera (r. br.) display toxicity upon egg hatching and larvae of aedes aegypti (linn.). | calotropis procera r. br. (asclepiadaceae) is a well-known medicinal plant with leaves, roots, and bark being exploited by popular medicine to fight many human and animal diseases. this work deals with the fractionation of the crude latex produced by the green parts of the plant and aims to evaluate its toxic effects upon egg hatching and larval development of aedes aegypti. the whole latex was shown to cause 100% mortality of 3rd instars within 5 min. it was fractionated into water-soluble dial ... | 2006 | 17072453 |
| immunological and allergenic responses induced by latex fractions of calotropis procera (ait.) r.br. | immunological and allergenic responses against the latex of calotropis procera were investigated in mice by oral and subcutaneous routes. the latex was fractionated according to water solubility and molecular size of its components. the fractions were named as non-dialyzable latex (ndl) corresponding to the major latex proteins, dialyzable latex (dl) corresponding to low molecular size substances and rubber latex (rl) which was highly insoluble in water. anti-sera against these fractions were as ... | 2007 | 17141437 |
| pro- and anti-inflammatory activities of the latex from calotropis procera (ait.) r.br. are triggered by compounds fractionated by dialysis. | previous studies have described pro- and anti-inflammatory activities displayed by the latex from calotropis procera. this report aims to clarify these observations and shows that such activities can be segregated from the whole latex. | 2006 | 17221170 |
| hepatoprotective and antioxidant activities of flowers of calotropis procera (ait) r. br. in ccl4 induced hepatic damage. | hepatoprotective activity of 70% ethanolic extract of flowers of c. procera was studied against ccl4 induced hepatic injury in albino rats and mice. in addition, antioxidant activity was studied by in vitro models. pre-treatment with 70% ethanolic extract (cpa) reduced the biochemical markers of hepatic injury like serum glutamate pyruvate transaminase, serum glutamate oxaloacetate transaminase, alkaline phosphatase, bilirubin, cholesterol, hdl and tissue glutathione (gsh) levels. similarly pret ... | 2007 | 17373378 |
| commonly used tropical medicinal plants exhibit distinct in vitro antioxidant activities against hepatotoxins in rat liver. | lipid peroxidation in biological systems has been considered as one of the major mechanisms of cell injury in aerobic organisms subjected to oxidation stress. plants, among other functions, are considered to act as free radical scavengers and as antioxidants. iron ii (fe(2+)), sodium nitroprusside (snp) and nitropropionic acid stimulate the production of free radicals and lipid peroxidation. in this study, four commonly used tropical medicinal plants (kigelia africana, calotropis procera, hibisc ... | 2007 | 17395447 |
| effect of railway engines emission on the micromorphology of some field plants. | plant species as indicator is the most common method used to indicate the effects of pollution on plants. however, the present study explores the usage of micromorphological parameters of the plant species as the indicators. the plants selected for the present studies included croton bonplandianum, cannabis sativa and calotropis procera. the parameters examined were (1) abnormalities of stomata, (2) number of stomata per unit area, (3) number of epidermal cells per unit area, (4) stomatal index. ... | 2006 | 17436526 |
| calotropis procera latex extract affords protection against inflammation and oxidative stress in freund's complete adjuvant-induced monoarthritis in rats. | in view of the well-established anti-inflammatory properties of latex of calotropis procera (dl), the present study was carried out to evaluate the protective effect of its methanol extract (medl) against inflammation and oxidative stress in monoarthritis induced by freund's complete adjuvant (fca) in rats. intra-articular injection of fca produced inflammation of the joint with a peak effect occurring on day 4 where a maximum increase in the levels of myeloperoxidase and inflammatory mediators ... | 2007 | 17497032 |
| calotropis procera latex-induced inflammatory hyperalgesia - effect of bradyzide and morphine. | 1 the milky white latex of the plant calotropis procera induces inflammatory response upon accidental exposure and on local administration that could be effectively ameliorated by antihistaminic and standard anti-inflammatory drugs. 2 the aim of the present study was to evaluate the anti-oedematogenic and analgesic effect of the bradykinin antagonist, bradyzide (bdz) and the opioidergic analgesic, morphine (mor) against inflammatory hyperalgesia induced by the dried latex (dl) of c. procera in t ... | 2007 | 17584444 |
| hepatoprotective activity of calotropis procera flowers against paracetamol-induced hepatic injury in rats. | hydro-ethanolic extract (70%) of calotropis procera flowers was prepared and tested for its hepatoprotective effect against paracetamol-induced hepatitis in rats. alteration in the levels of biochemical markers of hepatic damage like sgpt, sgot, alp, bilirubin, cholesterol, hdl and tissue gsh were tested in both treated and untreated groups. paracetamol (2 g/kg) has enhanced the sgpt, sgot, alp, bilirubin and cholesterol levels and reduced the serum levels of hdl and tissue level of gsh. treatme ... | 2007 | 17600635 |
| in vitro cytotoxicity against different human cancer cell lines of laticifer proteins of calotropis procera (ait.) r. br. | this work evaluated the in vitro cytotoxic activity of laticifer proteins (lp) recovered from the latex of the medicinal plant calotropis procera. the lp displayed considerable cytotoxicity with ic(50) values ranging from 0.42 to 1.36 microg/ml to sf295 and mda-mb-435 cell lines, respectively. in healthy peripheral blood mononuclear cells exposed to lp (10 microg/ml) for 72 h, no noticeable effects on viability or cell morphology were seen. the fractionating of lp on an ion exchange chromatograp ... | 2007 | 17604595 |
| bullous eruption with calotropis procera--a medicinal plant used in india. | 2007 | 17656917 | |
| calotropis procera latex affords protection against carbon tetrachloride induced hepatotoxicity in rats. | in the present study, latex of calotropis procera possessing potent antioxidant and anti-inflammatory properties was evaluated for its hepatoprotective effect against carbon tetrachloride (ccl(4)) induced hepatotoxicity in rats. subcutaneous injection of ccl(4,) administered twice a week, produced a marked elevation in the serum levels of aspartate transaminase (ast), alanine transaminase (alt) and tumor necrosis factor alpha (tnf-alpha). histological analysis of the liver of these rats revealed ... | 2007 | 17706384 |
| genetic diversity in some perennial plant species with-in short distances. | distinct morphophysiological variations observed for over 2 years with-in short distances among four perennial plants indicated genetic diversity among the lines growing at three places. the isozyme and sds polyacrylamide gel banding patterns as genetic markers were used to investigate four perennial species, namely dalbergia sissoo roxb., delonix regia (boj.) refin., cassia fistula l. and calotropis procera r. br. plant materials collected from three locations (agra, gwalior and lucknow) differ ... | 2007 | 17717991 |
| enzymatic activities and protein profile of latex from calotropis procera. | the laticifer fluid of calotropis procera is rich in proteins and there is evidence that they are involved in the pharmacological properties of the latex. however, not much is known about how the latex-containing proteins are produced or their functions. in this study, laticifer proteins of c. procera were pooled and examined by 1d and 2d electrophoresis, masses spectrometry (maldi-tof) and characterized in respect of proteolytic activity and oxidative enzymes. soluble laticifer proteins were pr ... | 2016 | 17888673 |
| biosorptive removal of cadmium from contaminated groundwater and industrial effluents. | the cadmium removing capacity of a biosorbent calotropis procera, a perennial wild plant, is reported here. the biomass was found to possess high uptake capacity of cd(ii). adsorption was ph dependent and the maximum removal was obtained at two different ph i.e. ph 5.0 and 8.0. maximum biosorption capacity in batch and column mode was found to be 40 and 50.5 mg/g. the adsorption equilibrium (> or =90% removal) was attained within 5 min irrespective of the cadmium ion concentration. interfering i ... | 2008 | 17892931 |
| decontamination and/or revegetation of fly ash dykes through naturally growing plants. | present study is focused on the decontamination and/or revegetation of fly ash dykes through naturally growing plants, namely calotropis procera, cassia tora, chenopodium album, sida cardifolia, blumea lacera. the results of sequential extraction study showed that maximum amount of metals (na, k, fe, mn, cr, pb, ni, cd) were associated with residual and fe-mn fractions. diethylenetriamine penta acetic acid (dtpa)-triethanolamine (tea) extraction assessed the bioavailability of the metals. the to ... | 2008 | 17964714 |
| acetaminophen-induced liver damage in mice: effects of some medicinal plants on the oxidative defense system. | paracetamol (acetaminophen, pcm) is widely used as an over-the-counter analgesic and antipyretic drug. intake of a large dose of pcm may result in severe hepatic necrosis. oxidative stress mediated by oxidative capacities of the pcm metabolite (n-acetyl-p-benzoquinoneimine (napqi), is considered as the main cause of hepatotoxicity of pcm. this work therefore seeks to induce liver damage in mice using single dose (25 0mg/kg) of acetaminophen and to evaluate the possible protective effects of admi ... | 2008 | 18054472 |
| biosorptive removal of ni(ii) from wastewater and industrial effluent. | the objective of the present work was to investigate the removal of ni(ii) by the fresh biomass (fbm) and chemically treated leached biomass (lbm) of calotropis procera. the scope of the work included screening of the biosorbents for their metal uptake potential, batch equilibrium, column mode removal studies and kinetic studies at varying ph (2-6), contact time, biosorbent dosages (1-25 g/l) and initial metal ion concentration (5-500 mg/l). the development of batch kinetic model and determinati ... | 2007 | 18180544 |
| tuareg ethnoveterinary treatments of camel diseases in agadez area (niger). | for generations, nomadic herders have been learning to manage herd health, particularly in dromedaries because of their great value. owing to the unavailability of veterinary services, camel herders in remote areas have been developing their own pharmacopoeia and veterinary techniques. the bleeding of sick animals is a common treatment, as tuareg herders believe that 'tainted blood' (izni) is the cause of many conditions. several surgical techniques are also used, such as excision of calcified s ... | 2007 | 18318345 |
| corneal endothelial cytotoxicity of the calotropis procera (ushaar) plant. | to report 6 eyes of 5 patients with transient corneal edema after exposure to the milky latex of calotropis procera (ushaar). | 2008 | 18434859 |
| heavy metal accumulation in medicinal plants collected from environmentally different sites. | to estimate the heavy metal content in soil and selected medicinal plants procured from environmentally different sites of the same city. | 2008 | 18837296 |
| molecular and biochemical evaluation of genetic effect of calotropis procera (ait.) latex on aspergillus terreus (thom). | the present study was conducted to observe the genotoxic effect of latex of calotropis procera. dense conidial suspensions of aspergillus terreus thorn were treated with different concentrations of calotropis latex and assayed for percentage survival, auxotrophic mutants, dna and total protein contents and further subjected to rapd and sds-page tests. it was found that latex of calotropis procera had potent lethal and mutagenic activities. percentage survival decreased as concentration or time o ... | 2008 | 19024171 |
| protective effect of latex of calotropis procera in freund's complete adjuvant induced monoarthritis. | the protective effect of latex of calotropis procera in freund's complete adjuvant (fca) induced monoarticular arthritis was evaluated in rats. arthritis was induced by a single intra-articular injection of 0.1 ml of 0.1% fca in the right ankle joint. the effect of dried latex (dl, 200 and 400 mg/kg) and its methanol extract (medl, 50 and 500 mg/kg) following oral administration was evaluated on joint inflammation, hyperalgesia, locomotor function and histology at the time of peak inflammation. ... | 2009 | 19048609 |
| calotropis procera -induced keratitis. | calotropis procera produces copious amounts of latex, which has been shown to possess several pharmacological properities. its local application produces intense inflammatory response. in the 10 cases of calotropis procera -induced keratitis reported here, the clinical picture showed corneal edema with striate keratopathy without any evidence of intraocular inflammation. the inflammation was reversed by the local application of steroid drops. | 2014 | 19075415 |