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molecular characterization and phylogenetic analysis of quinolone resistance-determining regions (qrdrs) of gyra, gyrb, parc and pare gene loci in viridans group streptococci isolated from adult patients with cystic fibrosis.ciprofloxacin is the most frequently used member of the fluoroquinolones during initial eradication therapy of pseudomonas aeruginosa, as well as during acute pulmonary exacerbations. however, its long-term effect on the susceptibility of the commensal flora within the cystic fibrosis (cf) airways has not yet been examined. the aim of this study was therefore to examine the consequence of oral ciprofloxacin usage on the resistance of the commensal viridans group streptococci (vgs), in terms of m ...201021193474
molecular characterization of macrolide resistance determinants [erm(b) and mef(a)] in streptococcus pneumoniae and viridans group streptococci (vgs) isolated from adult patients with cystic fibrosis (cf).although long-term use of azithromycin has shown a significant clinical improvement for patients with cystic fibrosis (cf), its long-term effect on the susceptibility of commensal flora within cf airways has not yet been examined. we therefore suggest that long-term use of azithromycin increases macrolide resistance in commensal streptococci.200919584106
streptococcus australis sp. nov., a novel oral streptococcus.strains of streptococci were isolated from the mouths of children attending the united dental hospital, sydney, australia. these strains were analysed biochemically using the rapid id32 strep microsystem, were subjected to dna-dna hybridization with other members of the oral streptococci and had their 165 rrna analysed. on the basis of dna-dna hybridization, their nearest relative was streptococcus parasanguinis, whereas, on the basis of 16s rrna analysis, it was streptococcus infantis. the name ...200111491323
streptococcus australis meningitis.we report a case of meningitis due to streptococcus australis, a newly described species of oral streptococcus. accurate identification was performed by various molecular techniques.201121737544
a highly arginolytic streptococcus species that potently antagonizes streptococcus mutans.the ability of certain oral biofilm bacteria to moderate ph through arginine metabolism by the arginine deiminase system (ads) is a deterrent to the development of dental caries. here, we characterize a novel streptococcus strain, designated strain a12, isolated from supragingival dental plaque of a caries-free individual. a12 not only expressed the ads pathway at high levels under a variety of conditions but also effectively inhibited growth and two intercellular signaling pathways of the denta ...201626826230
streptococcus rubneri sp. nov., isolated from the human throat.the novel, gram-stain-positive, ovoid, lactic acid bacterial isolates lmg 27205, lmg 27206, lmg 27207(t) and mri-f 18 were obtained from throat samples of healthy humans. 16s rrna gene sequence analyses indicated that these isolates belong to the genus streptococcus, specifically the streptococcus mitis group, with streptococcus australis and streptococcus mitis as the nearest neighbours (99.45 and 98.56 % 16s rrna gene sequence similarity to the respective type strains). genotypic fingerprintin ...201323749274
impact of periodontal therapy on the subgingival microbiota of severe periodontitis: comparison between good responders and individuals with refractory periodontitis using the human oral microbe identification microarray.this study compares the changes to the subgingival microbiota of individuals with "refractory" periodontitis (rp) or treatable periodontitis (good responders [gr]) before and after periodontal therapy by using the human oral microbe identification microarray (homim) analysis.201222324467
tetab46, a predicted heterodimeric abc transporter conferring tetracycline resistance in streptococcus australis isolated from the oral cavity.to identify the genes responsible for tetracycline resistance in a strain of streptococcus australis isolated from pooled saliva from healthy volunteers in france. s. australis is a viridans streptococcus, originally isolated from the oral cavity of children in australia, and subsequently reported in the lungs of cystic fibrosis patients and as a cause of invasive disease in an elderly patient.201322941900
the microbiome in populations with a low and high prevalence of caries.the oral microbiota was compared between romanian adolescents with a high prevalence of caries and no dental care and swedish caries-active and caries-free adolescents in caries prevention programs and with a low prevalence of caries. biofilm samples were analyzed by flx+ pyrosequencing of the v1 to v4 hypervariable regions of the 16s rrna gene and polymerase chain reaction (pcr)/quantitative pcr (qpcr) for streptococcus mutans and streptococcus sobrinus. sequences obtained blasted to 9 phyla, 6 ...201626442950
uv-c-irradiation sublethal stress does not alter antibiotic susceptibility of the viridans group streptococci to β-lactam, macrolide, and fluoroquinolone antibiotic agents.previous work has indicated that environmental stresses on bacteria might lead to an upregulation of stress response. led curing lights (315-400 nm) and other uv lights used in tooth whitening cosmetic procedures might act as stresses. we examined the effect of uv-c light, as a high-energy surrogate to the lower-energy uv-a light used in such instruments, to examine its effect on the antibiotic susceptibility of viridans group streptococci.201122887906
the oral bacterial microbiome of occlusal surfaces in children and its association with diet and caries.dental caries is the most prevalent disease in humans globally. efforts to control it have been invigorated by an increasing knowledge of the oral microbiome composition. this study aimed to evaluate the bacterial diversity in occlusal biofilms and its relationship with clinical surface diagnosis and dietary habits. anamneses were recorded from thirteen 12-year-old children. biofilm samples collected from occlusal surfaces of 46 permanent second molars were analyzed by 16s rrna amplicon sequenci ...201728678838
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