[immunization of papio papio monkeys by subcutaneous or respiratory route by means of hemagglutinating subunits of human grippe virus]. 19694979396
the role of visual reafferents during a pointing movement: comparative study between open-loop and closed-loop performances in monkeys before and after unilateral electrolytic lesion of the substantia order to elucidate the compensatory role of visual feedback during movement, two experiments were designed to compare the motor performances of papio papio baboons depending on whether the animals were able to visually control the limb trajectory (visual closed-loop condition) or not (visual open-loop condition). the visuomotor task used consisted of making trained pointing movements towards a stationary target. in experiment a, the baboons were successively presented with these two experimen ...19873556467
[stereological analysis of normal papio papio liver parenchymal cells (author's transl)].stereological analysis of normal papio papio liver parenchymal cells has been performed according to the method of weibel (1969). the study was carried out on liver samples collected from 3 males and 3 females. sampling was done at three levels of magnification (x 250, x 5 000, x 15 000) without taking into consideration the lobular variations. the lobular stereological model included the hepatocyte, all the cellular organelles and the extra-hepatocytic space compartment. surface and volume dens ...19807212697
initiation of a goal-directed movement in the monkey. role of the cerebellar dentate nucleus.the participation of the dentate nucleus (dn) in the initiation of a voluntary movement was investigated in five baboons (papio papio). in these experiments, we have analyzed the effects of excluding the dn on the latency (reaction time, rt) of a learned goal-directed movement. two techniques were for excluding the dn. in three animals, the structure was cooled with a probe, stereotaxically implanted on the side ipsilateral to the active hand. in two others, a partial electrolytic destruction of ...19807428885
conservation of the human col1a1-tk-gaa synteny and homoeologous assignment in the african green monkey and the baboon (cercopithecoidae).the pro alpha 1 (i) collagen structural gene (col1a1), the acid alpha-glucosidase (gaa), and the thymidine kinase (tk) genes, known to be closely linked in man (hsa) and mapped to hsa17, were found syntenic in two cercopithecoidae species, the baboon (papio papio, ppa) and the african green monkey (cercopithecus aethiops, cae) and assigned to homoeologous chromosomes, ppa16 and cae19, respectively. the assignment of col1a1 was obtained using two human cdna probes. hind iii restriction sites foun ...19846096258
assessment of cell-mediated immunity against coxsackievirus b3-induced myocarditis in a primate model (papio papio).delayed hypersensitivity and myocarditis were induced in five baboons (papio papio) after inoculation with myocarditic murine coxsackievirus b3 (cvb3m). by means of the [3h]thymidine incorporation assay and the agarose droplet cell migration inhibition assay, specific cell-mediated immunity was detected in all five animals against viral antigens and/or kcl-extractable soluble antigens extracted from the heart of a cvb3m-inoculated baboon. kcl-extracted antigens from normal baboon heart tissues, ...19816260666
seed-eating by west african cercopithecines, with reference to the possible evolution of bilophodont on tooth use in eating fruits and seeds were collected on 12 west african monkeys representing five species of cercopithecines, cercopithecus aethiops, cercopithecus campbelli, cercocebus atys, erythrocebus patas, and papio papio. field observations and information in the published literature were used to select fruits for captive feeding trials. a total of over 27,000 tests were conducted to determine the preferences of the monkeys for 78 fruits. data were collected on the selection of fru ...19883364545
processing of global and local visual information and hemispheric specialization in humans (homo sapiens) and baboons (papio papio).global precedence was examined in 8 baboons and 14 humans using compound stimuli presented in the left visual hemifield (lvf) or the right visual hemifield (rvf). humans showed a global advantage and global-to-local interference. baboons showed a local advantage and no interference. for humans and baboons, a lvf advantage appeared for global matching and an unsignificant rvf advantage appeared for local matching. the local advantage in baboons still emerged when the memory load of the task was r ...19979104003
heterogeneity of hepatic microsomal udp-glucuronosyltransferase(s) activities: comparison between human and mammalian species activities.the first comparative profiles of udp-glucuronosyltransferase(s) (udpgt) activities obtained under standard conditions in vitro in mammals (man, rat [wistar and gunn], mouse, monkey [papio papio and cynomolgus], pig, guinea pig, rabbit, dog) are presented for 16 aglycones. a decreasing scale of these activities was obtained from planar to bulky molecules. the scale was identical for each of the mammals studied, including man. statistical analysis of the results revealed a division of the aglycon ...19846439424
[action of psilocybine on visual evoked potentials in a cercopithecidae papio papio]. 19664228389
[saccharomyes telluria, a yeast of the animal digestive flora, particularly common in the baboon, papio papio (author's transl)]. 19744467778
heredofamilial retinal dystrophy in guinea baboons. i. a histopathologic study.we performed a histopathologic study of a heredofamilial retinal dystrophy in a colony of guinea baboons. a bull's-eye appearance was noted in the maculas of six baboons of three generations. histologic examination of 13 eyes from this colony showed primary degeneration of both rod and cone cells initially in the parafoveal region, which subsequently involved the photoreceptor cells of the equator and periphery of the retina. the retinal pigment epithelium and choriocapillaris showed mild change ...19836626015
physostigmine antagonizes benzodiazepine-induced myoclonus in the baboon, papio papio.the antagonism of some benzodiazepine (bz) actions by physostigmine was investigated in 4 papio papio baboons. as a model of these actions, the myoclonus induced in this species by clonazepam i.m. administration was used. the baboon develops, 20-30 min after bz i.m. injection, a non-epileptic myoclonus characterized by clinical symptomatology (jerks involving mainly the neck and the trunk bilaterally), by the absence of any correlative eeg discharge, and by its facilitation during movement. this ...19846527840
[thymosin-testosterone interaction in spontaneous rosette formation in the baboon monkey (papio papio)].thymosine fraction v was shown to exert a stimulation activity on t lymphocytes from papio papio, as determined by e. rosette and active e. rosette formation. testosterone inhibited this effect of thymosin.19836627910
synthetic peptide strategy for the detection of and discrimination among highly divergent primate lentiviruses.we developed a simple, rapid, inexpensive, and highly sensitive and specific strategy for the detection and lineage differentiation of primate lentiviruses (piv-elisa). it is based on the use of two indirect elisa methods using synthetic peptides mapping the gp41/36 region (detection component) and the v3 region (differentiation component) of four lentivirus lineages, namely sivcpz/hiv-1 (groups m, o, n, and sivcpz-gab), sivmnd, sivagm, and sivsm/sivmac/hiv-2. this strategy was evaluated with pa ...200111461679
comparison of phospholipid indicators of fetal lung maturity in the amniotic fluid of the monkey (macaca mulatta) and baboon (papio papio). 19744412536
the influence of d-penicillamine treatment upon seizure activity and trace metal status in the senegalese baboon, papio papio.reports suggesting participation of trace metals in processes of seizure initiation and propagation in humans and experimental animals prompted an investigation of the relationship between copper and zinc status and seizure activity in the senegalese baboon, papio papio. an evaluation of serum trace metal concentrations in three species of nonhuman primates revealed the presence of elevated zinc levels in p. papio moderately sensitive to photically induced seizures, compared with mildly seizure- ...19817205648
[connections of the laterodorsal nucleus of the thalamus in the monkey. study of efferents].efferent pathways of the ld nucleus of the thalamus were studied in 6 papio-papio baboons with the retrograde transport technique utilizing hrp. injections were made in cingular and parietal cortex and hippocampal formation. large projection from the ld to the cingular and subicular cortex were visualized as reciprocal connections. no pathway to parietal area 7 was found. the course of the fibers is via the fornix, the cingular bundle and the retro-lenticular portion of the internal capsule. the ...19846505490
[the problem of the use of mercurials cosmetics in senegal (author's transl)].the use of skin-lightening preparations appears to be a problem for the coloured women in africa as well as for the black people in general. the mercurial creams occupy a place of choice into the most useful products for the skin depigmentation. an epidemiological study from twenty senegalese women using mercurials cosmetics has permitted to determine a mean value of 155,75 +/- 75,38 ppm hg in scalp hair while the normal level is less than 10 ppm. an experimental study was realised with monkeys ...19817302943
[on the chromosomes of cercopithecidae papio-papio, macaca mulatta, cercopithecus aethiops, erythrocebus patas]. 196414210582
[chromosome study of the monkey, papio papio]. 196414228194
cloning and sequencing of baboon and cynomolgus monkey intra-acrosomal protein sp-10: homology with human sp-10 and a mouse sperm antigen (msa-63).in this study, cdnas encoding the intraacrosomal protein sp-10 were cloned and sequenced from baboon (papio papio) and macaque (macaca fascicularis) testis libraries and the sequence compared to that of human sp-10. two alternatively spliced sp-10 cdnas were obtained from both baboon and macaque testis libraries. the two cdnas in each species contained open reading frames encoding proteins of exactly 285 and 251 amino acids. a 98% homology between baboon and macaque sp-10 was found at the protei ...19938442953
production of 18f-labelled 2-deoxy-2-fluoro-d-glucose and preliminary imaging allow an additional approach to the study of brain metabolism in our laboratory, the synthesis of 18f-2-deoxy-2-fluoro-d-glucose (18fdg) has been adapted by the development of simple, reliable control techniques for routine use. by positron emission computed tomography, it has been established, in the baboon papio papio, that there was a correlation between an epileptic focus and an increase in glucose incorporation. on the other hand, in man, a comparison between the local glucose utilizatio ...19826981509
intronic sequence motifs of hla-dqb1 are shared between humans, apes and old world monkeys, but a retroviral ltr element (dqltr3) is human specific.long terminal repeats (ltrs) of the human endogenous retrovirus k (herv-k) family have been found at several sites within the human genome, of which one is located in the vicinity of hla-dqb1. since this dqltr3 is only present on some haplotypes, we performed a linkage analysis in 130 caucasian families. in order to date the integration event we also investigated the presence of this dqltr3 in apes and old world monkeys. additionally, we sequenced the adjacent region of dqltr3-positive and -nega ...199910395105
control of the corridor illusion in baboons (papio papio) by gradient and linear-perspective depth cues.the corridor illusion was recently demonstrated in baboons with background pictures containing rich depth information (barbet and fagot 2002, behavioural brain research 132 111-115). in the current research we determined the contribution of gradient texture and perspective lines to that illusion. in experiment 1, the corridor illusion was tested in two baboons, with pictures of a hallway as backgrounds, or the same image of the hallway represented by perspective lines. findings confirmed that th ...200717455754
control of lipolysis in intra-abdominal fat cells of nonhuman primates: comparison with humans.the mechanisms that control lipolysis in intra-abdominal fat cells from various primate species, the marmoset (callithrix jacchus), the baboon (papio papio), and the macaque (macaca fascicularis), were compared to those of human intraabdominal fat cells. selective beta 1- or beta 2-adrenoceptor agonists induced lipolysis in all species. selective beta 3-agonists (brl 37344, cl 316243, and sr 58611) acted as partial agonists in marmoset but were inefficient in other primates, including humans. al ...19957775857
beta-adrenergic control of lipolysis in primate white fat cells: a comparative study with nonprimate mammals.the beta-adrenoceptor subtypes involved in the control of lipolysis in white fat cells of rat, dog, marmoset (callithrix jacchus), baboon (papio papio), macaque (macaca fascicularis), and human were compared. in all species [3h]cgp-12177 binding (up to 3 nm) indicated the existence of a homogeneous population of binding sites in fat cell membranes, and competition studies showed that beta 1- and beta 2-adrenoceptors were present. selective beta 1 or beta 2-adrenoceptor agonists induced lipolysis ...19947914069
a review of the preclinical pharmacology of tiagabine: a potent and selective anticonvulsant gaba uptake inhibitor.we review the neurochemical and behavioral profile of the selective gamma-aminobutyric acid (gaba) uptake inhibitor, (r)-n-(4,4-di-(3-methylthien-2-yl)but-3-enyl) nipecotic acid hydrochloride [tiagabine (tgb), previously termed nnc 05-0328, no 05-0328, and no-328], which is currently in phase iii clinical trials for epilepsy. tgb is a potent, and specific gaba uptake inhibitor. tgb lacks significant affinity for other neurotransmitter receptor binding sites and/or uptake sites. in electrophysiol ...19957555976
primary (idiopathic) generalized epilepsy and underlying mechanisms.primary generalized epilepsy (pge) has been more hotly debated over the past decades than other forms of epileptic seizure disorder. the sudden synchronous appearance of bilateral spikes and spike-waves (mainly with myoclonus resp. absence) used to perplex the earliest generation of electroencephalographers, and the enigmatic genesis of these discharges (and seizures) has not ceased to fascinate the investigators of this phenomenon. a "centrencephalic" concept with paroxysmal discharges arising ...19968719497
comparative analysis of muscle architecture in primate arm and forearm.a comparative study of myological morphology, i.e. muscle mass (mm), muscle fascicle length and muscle physiological cross-sectional area (an indicator of the force capacity of muscles), was conducted in nine primate species: human (homo sapiens), chimpanzee (pan troglodytes), gibbon (hylobates spp.), papio (papio hamadryas), lutong (trachypithecus francoisi), green monkey (chlorocebus aethiops), macaque monkey (macaca spp.), capuchin monkey (cebus albifrons) and squirrel monkey (saimiri sciureu ...201019958344
genetic animal models of epilepsy as a unique resource for the evaluation of anticonvulsant drugs. a review.genetic animal models of epilepsy comprise genetically predisposed animal species in which seizures either occur spontaneously or in response to sensory stimulation. the major advantage of these naturally occurring epilepsies in animals as models of human epilepsy is that they simulate the clinical situation more closely than any other experimental epilepsy. models with idiopathic spontaneous recurrent seizures are epileptic dogs, tottering mice, and rats with spike-wave absence (petit mal) seiz ...19846439966
reflex epilepsy in the papio-papio baboon, particularly photosensitive epilepsy.papio-papio baboons may present two types of reflex paroxysmal manifestations: --myoclonia and generalized seizures are induced by intermittent light stimulation in predisposed animals; this photosensitive epilepsy resembles that observed in some human patients; it involves mainly the cerebral cortex during myoclonia which are accompanied by eeg paroxysmal discharges, and the mesencephalic reticular formation during seizures; --myoclonia of a different type, never accompanied by eeg paroxysmal d ...19957642345
behavioural and convulsant actions of two methyl esters of beta-carboline-3-carboxylic acid in photosensitive baboons and in dba/2 mice.the proconvulsant and convulsant actions of methyl 6,7-dimethoxy-4-ethyl-beta-carboline-3-carboxylate (dmcm) and of methyl-beta-carboline-3-carboxylate (beta-ccm) have been evaluated in two animal models of reflex epilepsy, the photosensitive baboon, papio papio, and the audiogenic seizure prone dba/2 mouse. in baboons, myoclonic responses to photic stimulation are markedly enhanced 1 min after dmcm, 0.25 mg/kg i.v. in the absence of photic stimulation dmcm, 0.5 mg/kg i.v. induces a single brief ...19846499918
new gene assignments in the baboon and new chromosome homoeologies with man.eight new gene assignments were demonstrated in the baboon (papio papio, ppa) by cosegregation analysis of twelve hybrid clones obtained by fusion between ppa fibroblasts and a mouse cell line deficient in thymidine kinase. the following markers and syntenic groups were assigned: sod1 to ppa3, glo-me1 to ppa-4, pgm2 to ppa5, ckbb-sord to ppa7, ldhb to ppa11 and ldha to ppa14. these localizations are in agreement wit hthe following homoeologies with the human karyotype: ppa3-hsa21, ppa4-hsa6, ppa ...19836604489
patterns of gastro-intestinal parasites and commensals as an index of population and ecosystem health: the case of sympatric western chimpanzees (pan troglodytes verus) and guinea baboons (papio hamadryas papio) at fongoli, senegal.the exponential decline of great apes over the past 50 years has resulted in an urgent need for data to inform population viability assessment and conservation strategies. health monitoring of remaining ape populations is an important component of this process. in support of this effort, we examined endoparasitic and commensal prevalence and richness as proxies of population health for western chimpanzees (pan troglodytes verus) and sympatric guinea baboons (papio hamadryas papio) at fongoli, se ...201120853397
globus pallidus and motor initiation: the bilateral effects of unilateral quisqualic acid-induced lesion on reaction times in monkeys.the results of many experimental studies have shown that the globus pallidus (gp) is involved in the control of motor activities, particularly during motor execution. whether or not the gp is involved in the initiation phase is still a matter of controversy, however. this question was investigated in the present study in papio papio monkeys after gp lesion using a simple reaction time (rt) task, focusing particularly on the initiation phase. the monkeys were trained to perform this task, which c ...19947925805
comparative gene mapping of the baboon (papio papio) and new gene assignments were demonstrated in the baboon (papio papio) by cosegregation analysis of twelve cell hybrids obtained between ppa fibroblasts and a mouse cell line deficient in thymidine kinase. the following markers and syntenic groups were localized : gusb on ppa3 ; np-mpi-pkm2-idh2 on ppa7; ada on ppa10 and idh1 on ppa12. these results are consistent with the following homoeologies of ppa and hsa chromosomes : ppa3-hsa7 ; ppa7-hsa14 and 15 ; ppa10-hsa20 and ppa12-hsa2q19826979294
okt8 human phenotype expressed by papio papio monkey lymphocytes.the potential cross-reactivity between human and papio papio monkey lymphocyte antigens was investigated using various monoclonal antibodies specific for human t cell subsets and hla-dr antigens. monkey circulating lymphocytes expressed the okt8 antigen, specific for the suppressor/cytotoxic t cell population and the htla antigens. these reactivities were also detected on lymphoid cells in the thymus and lymph nodes of the papio monkey.19826982277
transient abolition of generalized photosensitive epileptic discharge in humans by apomorphine, a dopamine-receptor agonist.apomorphine, an agonist of dopamine receptors, blocks or significantly reduces photically induced seizures in the baboon (papio papio). we therefore studied the effect of subcutaneously administered apomorphine in 11 patients with generalized photosensitive epilepsy. visual evoked potentials were not altered by apomorphine, but in nine patients apomorphine transiently blocked the epileptic photosensitivity for an average of 45 minutes. therefore, dopaminergic mechanisms play a role in the pathop ...19807191513
spontaneous isolated lipoma of the choroid plexus in the baboon.a case of symptomless, solitary lipoma of the choroid plexus is described. the tumour was found in the left lateral ventricle of an adult female baboon (papio papio) in the course of post-mortem examination. routine histological investigation showed that the tumour was composed exclusively of characteristic adipose cells with scarce collagen septa and without other hamartoma-like constituents, such as glial cells, neurons, cartilage or muscle fibres. the tumour mass was lined by a typical single ...19948056876
irregular xenoantibodies against human red blood cells in papio anubis, p ursinus, p hamadryas, p papio, saimiri sciureus, and macaca mulatta: possible effect on xenotransplantation assess the presence of irregular xenoantibodies against human red blood cells (rbcs) in 6 primate species used in xenotransplantation and other experimental procedures.201020172355
[enumeration of keratinophilic fungi in a population of cynocephalus monkeys (papio papio)]. 19665987836
pictorial gaze cues do not enhance long-tailed macaques' performance on a computerised object-location task.the perception of pictorial gaze cues was examined in long-tailed macaques (macaca fascicularis). a computerised object-location task was used to explore whether the monkeys would show faster response time to locate a target when its appearance was preceded with congruent as opposed to incongruent gaze cues. despite existing evidence that macaques preferentially attend to the eyes in facial images and also visually orient with depicted gaze cues, the monkeys did not show faster response times on ...200616962253
manual and hemispheric specialization in the manipulation of a joystick by baboons (papio papio).manual performance asymmetries were examined in 8 baboons (papio papio). using a joystick, monkeys had to track and hit with a cursor a randomly moving target on a monitor. the left or right hand was tested first, depending on group assignment, followed by a transfer to the other hand. a transfer effect is reported for the total number of trials to criterion and total number of successful trials. no effect was found for response time. however, for both test and transfer, the group initially test ...19938447954
a study of the periocular projections towards the frontal cortex in papio papio. 20144129628
sequence and characterization of the sperm protein sp17 from the this study, cdnas encoding the sperm protein sp17 from the baboon (papio papio) have been cloned and sequenced. three clones, differing in the lengths of their 3' untranslated regions, were identified, which were encoded by mrna transcripts of 0.8-1.35 kb. the open reading frame encodes 163 amino acids with a predicted molecular mass of 18.8 kda. the baboon sp17 protein sequence is 97% identical to human sp17 but differs significantly by the addition of 12 amino acids at the c-terminal, provi ...19979110316
co-localization of glycine and gaba immunoreactivity in interneurons in macaca monkey cerebellar cortex.previous work demonstrates that the cerebellum uses glycine as a fast inhibitory neurotransmitter [ottersen op, davanger s, storm-mathisen j (1987) glycine-like immunoreactivity in the cerebellum of rat and senegalese baboon, papio papio: a comparison with the distribution of gaba-like immunoreactivity and with [3h]glycine and [3h]gaba uptake. exp brain res 66(1):211-221; ottersen op, storm-mathisen j, somogyi p (1988) colocalization of glycine-like and gaba-like immunoreactivities in golgi cell ...200616784818
blockade of photically induced epilepsy by 'dopamine agonist' ergot alkaloids.the effect of the intravenous administration of ergot alkaloids on epileptic responses to intermittent photic stimulation )ips) has been studied in adolescent baboons, papio papio, from senegal. ergocornine, 1--2 mg/kg, produced marked autonomic and behavioural effects, slowed the eeg, and abolished myoclonic responses to ips for 30--90 min. ergometrine, 1 mg/kg, activated the eeg and blocked the induction of myoclonic responses for 1--3 h. bromocriptine, 0.5--4 mg/kg, did not consistently preve ...199996470
the effect of acth and hcg on adrenal steroidogenesis in the neonatal baboon (papio papio). 1992206082
Age-dependant behavioral strategies in a visual search task in baboons (Papio papio) and their relation to inhibitory control.A computerized visual search task was presented to 18 guinea baboons (Papio papio) ranging from 2.7 to 14.3 years of age. The task, inspired from Hick's (1952) task, required detection of a target among a variable number of distractors equidistant to a start button. The reaction times (RTs) and movement times both increased with the number of distractors expressed in bits of information. However, the slope of RT per bit function correlated positively with age, whereas a negative correlation was ...201122142038
preliminary lack of evidence for simian odour preferences of savanna populations of anopheles gambiae and other malaria vectors.the behavioural response to several culicine and anopheline mosquitoes to the odour of alternative hosts (human vs monkey) arranged in a choice set-up using odour-baited entry traps (obets) was assessed in a field experiment in south-eastern senegal. the experimental protocol followed procedures analogous to those adopted in olfactometer laboratory tests. two adult cercopithecus aethiops and a child of similar mass slept inside separate tents and their odours were drawn to each one of two paired ...200112402527
[presence of anti-a or anti-b agglutinins in serums of monkeys papio papio desm]. 195613302881
comparison of grouping abilities in humans (homo sapiens) and baboons (papio papio) with the ebbinghaus illusion.this research comparatively assessed grouping mechanisms of humans (n = 8) and baboons (n = 8) in an illusory task that employs configurations of target and surrounding circles arranged to induce the ebbinghaus (titchener) illusion. analyses of response behaviors and points of subjective equality demonstrated that only humans misjudged the central target size under the influence of the ebbinghaus illusion, whereas baboons expressed a more veridical perception of target sizes. it is argued that h ...200718085924
localization of fcgr1 encoding fcgamma receptor class i in primates: molecular evidence for two pericentric inversions during the evolution of human chromosome 1.the human high-affinity receptor for immunoglobulin g, fcgammari (fcgr1), is encoded by a family of three genes that share over 95% sequence homology. curiously, the three genes in this recently duplicated gene family flank the centromere of human chromosome 1, with fcgr1b located at 1p12 and both fcgr1a and fcgr1c located at 1q21. we have previously speculated that a pericentric inversion could account for the separation of the genes in the fcgr1 family and explain their current chromosomal loc ...19989763663
synthesis of a fluorine-18 labeled derivative of epibatidine for in vivo nicotinic acetylcholine receptor pet imaging.epibatidine (exo-2-(2'-chloro-5'-pyridyl)-7-azabicyclo[2.2.1]heptane), a natural compound isolated from the skin of the ecuadorian poison frog epipedobates tricolor, is the most potent nicotinic acetylcholine receptor (nachr) agonist reported to date. in order to visualize and quantify in vivo these receptors in human brain using positron emission tomography (pet), [18f]norchlorofluoroepibatidine (exo-2-(2'-[18f]fluoro-5'-pyridyl)-7-azabicyclo[2.2.1]heptane), a fluorine-18 (t(1/2): 110 min) radi ...199910220033
[stereotaxic anatomy of the cerebellar nuclei of the baboon (papio papio)]. 20165004900
[preliminary results of electrographic effects on the section of the corpus callosum in photosensitive papio papio]. 20164995954
delta9-tetrahydrocannabinol and epilepsy in the photosensitive baboon, papio papio. 20154525183
photosensitive epilepsy of the baboon papio papio. 20165085037
automated testing of cognitive performance in monkeys: use of a battery of computerized test systems by a troop of semi-free-ranging baboons (papio papio).fagot and paleressompoulle (2009) published an automated learning device for monkeys (aldm) to test the cognitive functions of nonhuman primates within their social groups, but the efficiency of the aldm procedure with large groups remains unknown. in the present study, 10 aldm systems were provided ad lib to a troop of 26 semi-free-ranging baboons that were initially naive with computerized testing. the test program taught baboons to solve two-alternative forced choice (2afc) and matching-to-sa ...201020479182
comparative assessment of distance processing and hemispheric specialization in humans and baboons (papio papio).this comparative study explored the ability to process distance and its lateralization in humans and baboons. using a conditional matching-to-sample procedure in a divided-field format, subjects had to decide whether or not the distance between a line and a dot belonged to a short- or a long-distance category. experiments 1, 2, and 4 demonstrated the ability of baboons to process and categorize distances. moreover, humans showed better distance processing for right visual field/left hemisphere p ...19989853095
discriminating the relation between relations: the role of entropy in abstract conceptualization by baboons (papio papio) and humans (homo sapiens).two baboons (papio papio) successfully learned relational matching-to-sample: they picked the choice display that involved the same relation among 16 pictures (same or different) as the sample display, although the sample display shared no pictures with the choice displays. the baboons generalized relational matching behavior to sample displays created from novel pictures. further experiments varying the number of sample pictures and the mixture of same and different sample pictures suggested th ...200111676083
relative digit lengths and testosterone levels in guinea baboons.a growing body of literature suggests that the ratio of the lengths of the second to fourth digits (2d:4d) on human hands is sexually dimorphic and associated with prenatal exposure to gonadal hormones, circulating serum testosterone, and a number of psychological and behavioral measures. little research has investigated digit ratios in nonhuman species. in the present study, we investigated sex differences in digit ratios and their possible association with serum testosterone in a captive group ...200415053945
anticonvulsant action of a 1,5-benzodiazepine, clobazam, in reflex epilepsy.clobazam, an anxiolytic 1,5-benzodiazepine, has been evaluated as an anticonvulsant in 2 animal models. in mice showing sound induced seizures, clobazam, 1--4 mg/kg, i.p., blocked seizure responses for 1--2 hr. in senegalese baboons papio papio showing photically induced myoclonus or seizures, clobazam, 2--12 mg/kg, i.v., totally prevented such responses for up to 6 hr. in baboons pretreated with allylglycine, 170--185 mg/kg, a similar but briefer protection was induced by clobazam. neurological ...200198317
Hair cortisol levels track phylogenetic and age related differences in hypothalamic-pituitary-adrenal (HPA) axis activity in non-human primates.Hair has been shown to archive a uniquely time averaged signal of endocrine activity, and holds attractive advantages for both laboratory and field research. Prior research has explored the potential of hair hormone analysis to examine hormone-behavior relationships. To date, no research has focused on the potential of the technique to investigate age-related changes or taxon differences in endocrine function. It is known that non-human primate infants of many taxa exhibit high cortisol levels a ...201121893059
the influence of cortisone on eeg and seizure activity in the baboon papio papio.the ability of cortisone to modify eeg and seizure activity was investigated in the baboon, papio papio. acute intramuscular doses (0.5-4 mg/kg) caused a dose-dependent increase in seizure response to a flashing light stimulus. this increase in seizure response was apparent in both seizure duration and the spread of convulsive activity. along with enhancement of seizures, cortisone was found to cause marked changes in the eeg, ranging from the appearance of interictal paroxysmal activity to alte ...200089944
chimpanzees routinely fish for algae with tools during the dry season in bakoun, guinea.wild chimpanzees regularly use tools, made from sticks, leaves, or stone, to find flexible solutions to the ecological challenges of their environment. nevertheless, some studies suggest strong limitations in the tool-using capabilities of chimpanzees. in this context, we present the discovery of a newly observed tool-use behavior in a population of chimpanzees (pan troglodytes verus) living in the bakoun classified forest, guinea, where a temporary research site was established for 15 months. b ...201727813136
long-term associative memory capacity in man.long-term episodic memory depends on the retention of associative information, such as the relationship between a friend's face and his name, a home and its neighborhood, and a mint and its odor. how many of these associative links can be stored and recalled? many have considered memory's capacity, but relevant data are scant. some previous experiments on humans have assessed the retention of thousands of visual impressions using forced-choice picture recognition and have concluded that there ar ...200919966258
relational matching in baboons (papio papio) with reduced grouping requirements.analogical reasoning is a corner stone of human cognition, but the phylogenetic origins of this skill are still unknown. recent animal studies have suggested that only apes can solve the 2- by 2-item relational matching (rmts) analogy problem, with potential benefits of language- (premack, 1983) or token-training procedures (thompson, oden, & boysen, 1997). in this study, 6 baboons were initially trained in an rmts task in which the same and different relations were exemplified by compound stimu ...201020384399
observations on the susceptibility of sooty mangabeys (cerococebus fuliginosus) and a baboon (papio papio) to poliomyelitis. 194720255498
centre-embedded structures are a by-product of associative learning and working memory constraints: evidence from baboons (papio papio).influential theories have claimed that the ability for recursion forms the computational core of human language faculty distinguishing our communication system from that of other animals (hauser, chomsky, & fitch, 2002). in the present study, we consider an alternative view on recursion by studying the contribution of associative and working memory processes. after an intensive paired-associate training with visual shapes, we observed that baboons spontaneously ordered their responses in keeping ...201222225966
bloodfeeding patterns of sylvatic arbovirus vectors in southeastern senegal.dengue (denv), yellow fever (yfv) and chikungunya (chikv) viruses circulate in sylvatic, enzootic transmission cycles in southeastern senegal, but understanding of the vector-host interactions involved is limited.023423342
calcification of thymic hassal's corpuscles in prenatal and postnatal nonhuman primates.calcification of thymic hassal's corpuscles was found in three prematurely delivered fetuses, one each of the species papio papio, macaca mulatta, and saimiri sciureus. the cause of these lesions was not determined.19807464030
proconvulsant, convulsant and other actions of the d- and l-stereoisomers of allylglycine in the photosensitive baboon, papio papio.the effects of the intravenous or intracerebroventricular injection of the stereoisomers, and the racemic mixture, of allylglycine (2-amino-pent-4-enoic acid) have been studied in baboons, papio papio, with photosensitive epilepsy. enhancement of the natural syndrome of photosensitivy epilepsy is seen 1-12 h (maximally at 3-8 h) after l-allyglycine, 100 mg/kg, intravenously, or d,l-allyglycine, 200 mg/kg, intravenously. such enhancement is seen with a slower onset, and to a lesser, and more vari ...200089942
[observation of a photosensitive syndrome in macaca nemestrina (author's transl)].out of a group of 12 m. nemestrina (originating from malaysia), 9 adults had shown clinical signs induced by ils at 25 c/sec. six of them (3 males, 3 females) were very photosensitive; however, only 2 presented eyelid and/or head jerks after the end of ils (level 4), but never a generalized seizure. tactile periorbital stimuli favoured myoclonus. in all but the two of level 4, the intensity of clinical signs varied from one day to the next. in all implanted adult macaques, spontaneous paroxysmal ...19817323374
processing of biological motion point-light displays by baboons (papio papio).humans apply complex conceptual judgments to point-light displays (plds) representing biological motion (bm), but how animals process this kind of display remains uncertain. four baboons (papio papio) were trained to discriminate bm from nonbiological motion plds using an operant computerized test system. transfer tests were given after training with novel bm stimuli representing humans or baboons (experiment 1), with inverted plds (experiment 2), and with bm stimuli in which body parts had been ...200717924787
[electrophysiological effects of psilocybin in a cercopithecinae, papio papio]. 20144182890
drugs modifying dopaminergic activity and behaviour, the eeg and epilepsy in papio papio.acute changes in spontaneous motor activity, the eeg and photically induced epileptic responses have been observed in baboons (papio papio) following the i.v. injection of drugs acting on dopaminergic transmission. apomorphine hydrochloride, 0.5-1.0 mg/kg, produced a phase of acute excitement with accentuated vigilance and abnormal buccal motor activity lasting 30-40 min; during this phase myoclonic responses to intermittent photic stimulation were absent. after piribedil (et 495, 1,2'' -pyrimid ...19911149807
[photosensitive epilepsy in papio papio. a model of photosensitive epilepsy in humans]. 197318847049
discrimination of contour-deleted images in baboons (papio papio) and chimpanzees (pan troglodytes).humans readily group component elements into a coherent perceptual whole and perceive the global form of visual patterns in priority over local features, which stands in contrast to at least some data from the animal literature, suggesting possible species differences in perceptual processes. in this study, chimpanzees and baboons were required to match intact and partially contour-deleted line-drawings in a computerized task in order to further explore the ability of nonhuman primates to group ...201121225440
baboons (papio papio) spontaneously process the first-order but not second-order configural properties of faces.a two-alternative forced-choice discrimination task was used to assess whether baboons (n=7) spontaneously process qualitative (i.e., first-order) or quantitative (i.e., second-order) variations in the configural arrangement of facial features. experiment 1 used as test stimuli second-order pictorial faces of humans or baboons in which the mouth and the eyes were rotated upside down relative to the normal face. baboons readily discriminated two different normal faces but did not discriminate a n ...200818027865
conceptual thresholds for same and different in old-(macaca mulatta) and new-world (cebus apella) monkeys.learning of the relational same/different (s/d) concept has been demonstrated to be largely dependent upon stimulus sets containing more than two items for pigeons and old-world monkeys. stimulus arrays containing several images for use in same/different discrimination procures (e.g. 16 identical images vs. 16 nonidentical images) have been shown to facilitate and even be necessary for learning of relational concepts (flemming et al., 2007; wasserman et al., 2001; young et al., 1997). in the pre ...201121238555
mfasat: a new alphoid dna sequence isolated from macaca fascicularis (cercopithecidae, primates).a new highly repeated dna fragment isolated from macaca fascicularis (mfasat) is described. our findings obtained by sequencing, southern blot analysis, and fluorescent in situ hybridization (fish) on metaphasic chromosomes strongly suggest that mfasat can be considered as a member of the alphoid dna family characteristic of old world monkeys. the chromosomal localization of mfasat, obtained by fish, showed that this alphoid dna is present in the peri-centromeric area of all the chromosomes. mfa ...199910659771
alterations in learning performance in the seizure-prone baboon: effects of elicited seizures and chronic treatment with diazepam and phenobarbital.a comparison was made of the effects of chronically administered diazepam and phenobarbital with those of elicited seizures on repeated acquisition learning in 3 prepubertal papio papio. the learning task required the baboons each day to perform different sequences of lever presses on a three-lever behavior panel. middle dose levels of both diazepam and phenobarbital were found to improve learning performance relative to base-line control levels, as measured by total errors, efficiency, and time ...200198318
generalized relational matching by guinea baboons (papio papio) in two-by-two-item analogy problems.analogical reasoning is considered the hallmark of human reasoning, but some studies have demonstrated that language- and symbol-trained chimpanzees can also reason analogically. despite the potential adaptive value of this ability, evidence from other studies strongly suggests that other nonhuman primates do not have this capacity for analogical reasoning. in our three experiments, 6 of 29 baboons acquired the ability to perform a relational matching-to-sample (rmts) task in which pairs of shap ...201121934135
contrasted patterns of variation and evolutionary convergence at the antiviral oas1 gene in old world primates.the oligoadenylate synthetase 1 (oas1) enzyme acts as an innate sensor of viral infection and plays a major role in the defense against a wide diversity of viruses. polymorphisms at oas1 have been shown to correlate with differential susceptibility to several infections of great public health significance, including hepatitis c virus, sars coronavirus, and west nile virus. population genetics analyses in hominoids have revealed interesting evolutionary patterns. in central african chimpanzee, oa ...201526156123
divergent simian t-cell lymphotropic virus type 3 (stlv-3) in wild-caught papio hamadryas papio from senegal: widespread distribution of stlv-3 in africa.among eight samples obtained from a french primatology research center, six adult guinea baboons (papio hamadryas papio), caught in the wild in senegal, had a peculiar human t-cell leukemia virus type 2 (htlv-2)-like western blot seroreactivity (p24(+), gd21(+), k55(+/-)). partial sequence analyses of the tax genes (433 bp) indicated that these baboons were infected by a novel divergent simian t-cell lymphotropic virus (stlv). analyses of the complete proviral sequence (8,892 bp) for one of thes ...200312477886
[identity of karyotypes of papio papio and macaca mulatta in r, g, c banding and ag-nor]. 1978115371
[correlation between the regional blood volume and epileptic seizures in papio papio].the method of labelling red cells with technetium-99m was used to measured regional blood volume auring different types of epileptic seizures induced in the baboon papio papio. during seizures the cerebral blood volume increases and there is simultaneously a decrease of blood volume in nasal and hepatic regions, and a transitory increase of blood volume in the forepaws.2002117933
photically induced seizures in the yellow baboon, papio cynocephalus.significant susceptibility to photically induced seizures has in the past been observed only in senegales baboons (papio papio) and epileptic humans. however, we have unexpectedly observed a photomyoclonic response to intermittent photic stimulation in 5 of a sample of 6 yellow baboons (papio cynocephalus).2001114296
frequent attacks and anatomical lesions in the photosensitive papio papio. 20124103565
high prevalence of antibodies against the bacterium treponema pallidum in senegalese guinea baboons (papio papio).the bacterium treponema pallidum is known to cause syphilis (ssp. pallidum), yaws (ssp. pertenue), and endemic syphilis (ssp. endemicum) in humans. nonhuman primates have also been reported to be infected with the bacterium with equally versatile clinical manifestations, from severe skin ulcerations to asymptomatic. at present all simian strains are closely related to human yaws-causing strains, an important consideration for yaws eradication. we tested clinically healthy guinea baboons (papio p ...201526588087
a primate apol1 variant that kills trypanosoma brucei gambiense.humans are protected against infection from most african trypanosomes by lipoprotein complexes present in serum that contain the trypanolytic pore-forming protein, apolipoprotein l1 (apol1). the human-infective trypanosomes, trypanosoma brucei rhodesiense in east africa and t. b. gambiense in west africa have separately evolved mechanisms that allow them to resist apol1-mediated lysis and cause human african trypanosomiasis, or sleeping sickness, in man. recently, apol1 variants were identified ...201627494254
male tolerance and male-male bonds in a multilevel primate society.male relationships in most species of mammals generally are characterized by intense intrasexual competition, with little bonding among unrelated individuals. in contrast, human societies are characterized by high levels of cooperation and strong bonds among both related and unrelated males. the emergence of cooperative male-male relationships has been linked to the multilevel structure of traditional human societies. based on an analysis of the patterns of spatial and social interaction in comb ...201425201960
differences between chimpanzee and baboon gastrointestinal parasite communities.cross-species infection among humans, chimpanzees (pan troglodytes) and baboons (papio spp.) is potentially a significant public health issue in africa, and of concern in the conservation of p. troglodytes. however, to date, no statistical comparisons have been made between the prevalence, richness and composition of parasite communities in sympatric populations of baboons and p. troglodytes. we compared parasite communities in sympatric p. troglodytes and papio papio living in a wilderness site ...201525731985
demonstration of gaba immunoreactive cells in the inferior olive of baboons (papio papio and papio anubis).the distribution of gamma-aminobutyric acid (gaba)-like immunoreactivity was studied in semithin sections through the inferior olivary complex in two baboon species. about 5% of the olivary neurons were gaba-immunoreactive. the gaba-immunoreactive neurons differed from the large majority of olivary neurons by their smaller size and their lower contents of aspartate, as judged by analysis of alternate sections labelled with an aspartate antiserum. the present observations raise the possibility th ...19892671810
proceedings: examination of neural mechanism involved in photogenic seizure susceptibility in epileptic senegalese baboon: papio papio. 20154680334
the influence of social systems on patterns of mitochondrial dna variation in baboons.behavior is influenced by genes but can also shape the genetic structure of natural populations. investigating this link is of great importance because behavioral processes can alter the genetic diversity on which selection acts. gene flow is one of the main determinants of the genetic structure of a population and dispersal is the behavior that mediates gene flow. baboons (genus papio) are among the most intensely studied primate species and serve as a model system to investigate the evolution ...201424523566
distribution of distinct arachidonoyl-specific and non-specific isoenzymes of diacylglycerol kinase in baboon (papio cynocephalus) tissues.we investigated the diacyglycerol kinase species present in several baboon tissues using the substrates sn-1-stearoyl-2-arachidonoyl diacylglycerol and sn-1,2-didecanoyl diacylglycerol. chromatography of octyl glucoside extracts of the baboon (papio cynocephalus papio) tissues on hydroxyapatite columns revealed the presence of three diacylglycerol kinase species with different substrate preferences. one species markedly 'preferred' the substrate sn-1-stearoyl-2-arachidonoylglycerol, the two othe ...19902155609
effects of melatonin on the photosensitive epilepsy of the baboon, papio papio.the acute pharmacological effects of melatonin (5-methoxy-n-acetyl-tryptamine) were evaluated on behaviour and electrographic signs in the photosensitive baboon (papio papio), including visually evoked potentials veps). doses of 5 and 10 mg/kg i.v. had little effect, contrasting with the enhancement of spontaneous paroxysmal activity and latency of clinical signs elicited by intermittent light stimulation (ils) produced by the 20 and 50 mg/kg doses. moreover, a modification of the electrographic ...200160219
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