Publications

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the complete life cycle of a new strain of plasmodium gonderi from the drill (mandrillus leucophaeus), including its sporogony in anopheles aztecus and its pre-erythrocytic schizogony in the rhesus monkey. 195813625369
blood loss and replacement in plasmodial infections. iii. plasmodium cynomolgi, plasmodium gonderi and plasmodium knowlesi in macaca mulatta mulatta, the rhesus monkey. 196013847844
the blood-stages of plasmodium georgesi, p. gonderi and p. petersi: course of untreated infection in their natural hosts and additional morphological distinctive features.in the blood of a cercocebus albigena and of a c. galeritus agilis monkey, the infection with plasmodium gonderi was found to follow its well-known chronic course; p. georgesi seemed to occur as a relapsing type of malaria parasite; p. petersi was found for only a few days and at a low level in c. albigena (end of an attack?). as shown by using polarized light, the pigment granules appeared mostly as fine dots in p. georgesi, short rods in p. gonderi and long needles in p. petersi. the three spe ...19958559586
infection and transmission studies with plasmodium gonderi in the macaca mulatta monkey.eight different anophelines--anopheles freeborni, an. maculatus, an. dirus, an. stephensi, an. atroparvus, an. sundaicus, an. quadrimaculatus, and an. albimanus--were shown to be susceptible to infection with a strain of plasmodium gonderi from the drill. mandrillus leucophaeus. transmission was obtained via the bites of an. freeborni, an. maculatus, an. stephensi, and an. dirus mosquitoes to macaca mulatta. prepatent periods in macaca mulatta monkeys following sporozoite inoculation ranged from ...19807218123
the in vitro cultivation of plasmodium gonderi.plasmodium gonderi, one of the vivax-type simian parasites, has been cultured in vitro by the candle jar method and by the sealed flask method. it showed a 48-hour asexual cycle and maintained its morphologic integrity. the effect of different sera (human, rabbit, and horse) was tested in culture and compared with results using rhesus serum. growth was lower in rabbit and horse serum, but higher in human serum. compared with individual human and rhesus serum, the multiplication rate in combined ...19836859396
draft genome sequence of plasmodium gonderi, a malaria parasite of african old world monkeys.plasmodium gonderi is a primate parasite whose natural host is the african old world monkeys. here, we report the draft genome sequence for p. gonderi the data are useful not only for understanding the evolution of malaria but also for allowing the comparative genomics of malaria parasites.201728705975
african monkeys are infected by plasmodium falciparum nonhuman primate-specific strains.recent molecular exploration of the plasmodium species circulating in great apes in africa has revealed the existence of a large and previously unknown diversity of plasmodium. for instance, gorillas were found to be infected by parasites closely related to plasmodium falciparum, suggesting that the human malignant malaria agent may have arisen after a transfer from gorillas. although this scenario is likely in light of the data collected in great apes, it remained to be ascertained whether p. f ...201121730135
absence of cross-immunity between plasmodium cynomolgi and plasmodium gonderi. 195513306283
the development of exoerythrocytic stages of plasmodium inui shortti in new world monkeys.attempts are being made to adapt old world monkey malarial parasites to new world monkeys for vaccine and molecular studies. several of these (plasmodium cynomolgi berok, plasmodium fragile, and plasmodium knowlesi) grow readily but have failed to produce infective gametocytes. plasmodium gonderi and plasmodium fieldi develop in the liver after sporozoite inoculation but have failed to establish infection in the erythrocyte. anopheles dirus mosquitoes infected with plasmodium inui shortti by fee ...200312880277
infection of aotus and saimiri monkeys with plasmodium gonderi.attempts were made to infect 4 species of new world monkeys (saimiri boliviensis, aotus nancymai, a. vociferans, a. azarae boliviensis) with plasmodium gonderi, a malaria parasite of african monkeys. sporozoites were obtained from anopheles dirus or a. stephensi mosquitoes that fed on an infected rhesus monkey (macaca mulatta). inoculation of sporozoites was by injection of dissected sporozoites by either the intravenous or intrahepatic routes, or by mosquito bite. liver biopsies done 7 or 8 day ...200212054031
non-human primate malaria parasites: out of the forest and into the laboratory.the study of malaria in the laboratory relies on either the in vitro culture of human parasites, or the use of non-human malaria parasites in laboratory animals. in this review, we address the use of non-human primate malaria parasite species (nhpmps) in laboratory research. we describe the features of the most commonly used nhpmps, review their contribution to our understanding of malaria to date, and discuss their potential contribution to future studies.201627748213
the evolution and diversity of a low complexity vaccine candidate, merozoite surface protein 9 (msp-9), in plasmodium vivax and closely related species.the merozoite surface protein-9 (msp-9) has been considered a target for an anti-malarial vaccine since it is one of many proteins involved in the erythrocyte invasion, a critical step in the parasite life cycle. orthologs encoding this antigen have been found in all known species of plasmodium parasitic to primates. in order to characterize and investigate the extent and maintenance of msp-9 genetic diversity, we analyzed dna sequences of the following malaria parasite species: plasmodium falci ...201324044894
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