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genetic characteristics of canine distemper viruses circulating in wildlife in the united states.canine distemper virus (cdv) is a highly contagious disease of wild and domestic mammals. maintenance of cdv among wildlife plays an important role in the disease epidemiology. wild animals, including raccoons (procyon lotor) and gray foxes (urocyon cinereoargenteus), serve as reservoirs of cdv and hamper the control of the disease. recently, we discovered that at least three different cdv lineages (america-3 [edomex], america-4, and america-5] that are genetically different from the available v ...202031926508
infection of eight mesocarnivores in new hampshire and vermont with a distinct clade of canine distemper virus in 2016-2017.three fishers (martes pennanti), 2 gray foxes (urocyon cinereoargenteus), 1 mink (neovison vison), 1 skunk (mephitis mephitis), and 1 raccoon (procyon lotor), from vermont and new hampshire, had lesions on autopsy consistent with canine distemper virus (cdv) infections diagnosed in a 12-mo period in 2016-2017. lesions of cdv infection were most commonly noted in the lungs (8 of 8 animals), urothelium (5 of 8), biliary tract (5 of 8), gastrointestinal tract (4 of 7), and brain (4 of 6). splenic l ...201931023162
clinical and angiographic outcomes following endovascular treatment of very small (3 mm or smaller) intracranial aneurysm: a single-center experience.treatments for very small (3 mm or smaller) intracranial aneurysms (vsas) remain controversial. the aim of this study was to evaluate the efficacy of endovascular treatment for vsas and to evaluate clinical risk factors associated with complications.this retrospective study enrolled 82 vsa patients who underwent coil embolization in our institution. angiographic outcomes were assessed according to the meyers classification. the clinical results were evaluated using the modified rankin scale (mrs ...201728906352
winter bait stations as a multispecies survey tool.winter bait stations are becoming a commonly used technique for multispecies inventory and monitoring but a technical evaluation of their effectiveness is lacking. bait stations have three components: carcass attractant, remote camera, and hair snare. our 22,975 km(2) mountainous study area was stratified with a 5 × 5 km sampling grid centered on northern idaho and including portions of washington, montana, and british columbia. from 2010-14, we conducted 563 sampling sessions at 497 bait statio ...201728904763
potential effects of hormone therapy in type 2 idiopathic macular telangiectasia.to investigate the influence of hormone therapy with tamoxifen or estrogens on morphological changes in macular telangiectasia (mactel) type 2 patients as revealed clinically in multiple imaging modalities.201728903123
morphometric characteristics and coi haplotype diversity of arctodiaptomus spinosus (copedoda) populations in soda pans in hungary.arctodiaptomus spinosus (daday, 1891) is a characteristic species of the soda pan zooplankton in the great hungarian plain. the biogeographical distribution of the species is interesting, since its range expands from the pannonian biogeographic region to the other side of the carpathians, occurring in saline lakes in eastern anatolia, armenia, iran and in temporary waters in ukraine. our investigations focused on the morphometric characteristics and the coi haplotype diversity of four hungarian ...201728901808
characterization of differences between prostate cancer patients presenting with de novo versus primary progressive metastatic disease.men who present with metastatic disease can have de novo or primary progressive disease. we characterized and compared the outcomes between these 2 groups.201728899723
predicting preschool children's eating in the absence of hunger from maternal pressure to eat: a longitudinal study of low-income, latina mothers.early work by klesges et al. (1983, 1986) suggested that mothers who frequently prompt their children to eat have children at greater risk for obesity. this is consistent with the hypothesis that controlling feeding practices override children's responsiveness to their internal fullness cues, increasing the risk of overeating and obesity (e.g., johnson & birch, 1994). subsequent cross-sectional research on pressure to eat, however, has been inconsistent. most studies have shown that maternal sel ...201728899652
[miller fisher syndrome following treatment with certolizumab in a patient with rheumatoid arthritis].sindrome de miller fisher tras tratamiento con certolizumab en una paciente con artritis reumatoide.201728896005
splenectomy vs. rituximab as a second-line therapy in immune thrombocytopenic purpura: a single center experience.immune thrombocytopenic purpura (itp) is a common hematological disease treated primarily by corticosteroids. the aim of the present study was to compare response rate between patients, underwent splenectomy vs. rituximab as second-line therapy. adult patients diagnosed with itp who did not respond to corticosteroids or relapsed during the period 1990-2014 were included in a quasi-experimental study. categorical variables were compared using fisher exact test. response to treatment was compared ...201728895035
new prognostic factor telomerase reverse transcriptase promotor mutation presents without mr imaging biomarkers in primary glioblastoma.magnetic resonance (mr) imaging biomarkers can assist in the non-invasive assessment of the genetic status in glioblastomas (gbms). telomerase reverse transcriptase (tert) promoter mutations are associated with a negative prognosis. this study was performed to identify mr imaging biomarkers to forecast the tert mutation status.201728894890
a pilot study on the impact of dopamine, serotonin, and brain-derived neurotrophic factor genotype on long-term functional outcomes after subarachnoid hemorrhage.many that survive an aneurysmal subarachnoid hemorrhage experience lasting physical disability, which might be improved by medications with effects on the dopaminergic, serotonergic, and brain-derived neurotrophic factor neurotransmitter systems. but it is not clear which patients are most likely to benefit from these therapies. the purpose of this pilot study was to explore the relationship of genetic polymorphisms in these pathways with 12-month functional outcomes after aneurysmal subarachnoi ...201728894586
association of gastrointestinal functional disorders and migraine headache: a population base study.background migraine is one of the prevalent headaches. many of patients with migraine, complain of gastrointestinal symptoms. there is limited studies on relation of gastrointestinal symptoms and migraine headache at population level. methods in this population-based study, 1038 subjects older than 15 year from a rural area in fars province, south of iran. were investigated for functional gastrointestinal disorders. by cluster random sampling, 160 of these persons invited to receive endoscopy al ...201728894515
proptosis: a forgotten observation by miller fisher on his syndrome. 201728894030
diffusion tensor magnetic resonance imaging driven growth modeling for radiotherapy target definition in glioblastoma.the clinical target volume (ctv) in radiotherapy is routinely based on gadolinium contrast enhanced t1 weighted (t1w + gd) and t2 weighted fluid attenuated inversion recovery (t2w flair) magnetic resonance imaging (mri) sequences which have been shown to over- or underestimate the microscopic tumor cell spread. gliomas favor spread along the white matter fiber tracts. tumor growth models incorporating the mri diffusion tensors (dti) allow to account more consistently for the glioma growth. the a ...201728893125
diagnostic accuracy and surgical utility of mri in complicated diabetic foot.diabetic foot complications pose a significant public health hazard and have negative effect on life quality. these complications are associated with increased risk of amputations and premature death. so focus is increasing on early treatment of complicated diabetic foot.201728892986
distribution of sccmec elements and presence of panton-valentine leukocidin in methicillin-resistant staphylococcusepidermidis isolated from clinical samples in a university hospital of isfahan city, iran.coagulase negative staphylococcus (cons) is considered as a major pathogen of nosocomial infections among immunosuppressed patients.201728892893
active surveillance of health care associated infections in neurosurgical patients.health care associated infections (hcai) are frequent complications in neurosurgery. there is limited data available on the incidence and burden of hcai in neurosurgical patients of southeast asian region.201728892887
polytrauma defined by the new berlin definition: a validation test based on propensity-score matching approach.background: polytrauma patients are expected to have a higher risk of mortality than that obtained by the summation of expected mortality owing to their individual injuries. this study was designed to investigate the outcome of patients with polytrauma, which was defined using the new berlin definition, as cases with an abbreviated injury scale (ais) ≥ 3 for two or more different body regions and one or more additional variables from five physiologic parameters (hypotension [systolic blood press ...201728891977
[overall survival and renal function after partial and radical nephrectomy in malignant localized renal tumors.]to evaluate the overall survival rate and renal function in our series after radical nephrectomy (rn) and partial nephrectomy (pn) in renal tumors in an early stage.201728891797
caloric restriction promotes rapid expansion and long-lasting increase of lactobacillus in the rat fecal microbiota.previous studies indicated that caloric restricted diet enables to lower significantly the risk of cardiovascular and metabolic diseases. in experimental animal models, life-long lasting caloric restriction (cr) was demonstrated to induce changes of the intestinal microbiota composition, regardless of fat content and/or exercise. to explore the potential impact of short and long-term cr treatment on the gut microbiota, we conducted an analysis of fecal microbiota composition in young and adult f ...201728891744
prevalence of endometriosis and its symptoms among young jordanian women with chronic pelvic pain refractory to conventional therapy.this study sought to explore the prevalence and clinical manifestations of endometriosis in young women with chronic pelvic pain (cpp) refractory to conventional medical therapy.201728890178
yamamoto new scalp acupuncture for postoperative pain management in cats undergoing ovariohysterectomy.to evaluate the analgesic efficacy of yamamoto new scalp acupuncture (ynsa) as an adjuvant for postoperative pain management in cats.201728888802
early electrophysiological findings in fisher-bickerstaff syndrome.the term fisher-bickerstaff syndrome (fbs) has been proposed to describe the clinical spectrum encompassing miller-fisher syndrome (mfs) and bickerstaff brainstem encephalitis. the pathophysiology of fbs and the nature of the underlying neuropathy (demyelinating or axonal) are still subject to debate. this study describes the main findings of an early neurophysiological study on 12 patients diagnosed with fbs.201728888467
safety and effectiveness of oral misoprostol for induction of labour in a resource-limited setting: a dose escalation study.oral misoprostol as an induction of labour (iol) agent is rapidly gaining popularity in resource-limited settings because it is cheap, stable at ambient temperatures, and logistically easier to administer compared to dinoprostone and oxytocin. we aim to investigate the safety and effectiveness of a regimen of oral misoprostol in papua new guinean women undergoing iol.201728886702
a retrospective volume matched analysis of the submental artery island pedicled flap as compared to the forearm free flap: is it a good alternative choice for the reconstruction of defects of the oral cavity and oropharynx?the submental artery island pedicled flap (smif) is an underused alternative for reconstruction of head and neck defects after tumor ablation. the purpose of this study was to perform a comparative evaluation of reconstructive outcomes based on surgical site and ablative defect volume in patients who underwent reconstruction with the smif versus the forearm free flap (fff).201728886357
outcomes of abdominal surgery in patients with mechanical ventricular assist devices: a multi-institutional study.the aim of this study was to examine the outcomes of elective and emergent abdominal operations performed in end-stage heart failure patients supported with ventricular assist devices (vads).201728885501
ridge preservation after maxillary third molar extraction using 30% porosity plga/ha/β-tcp scaffolds with and without simvastatin: a pilot randomized controlled clinical trial.to evaluate clinically and radiographically, in humans, the healing of maxillary third molars postextraction sockets after application of different ridge preservation techniques 3 months after tooth extraction.201728885317
is infantile colic an early life expression of childhood migraine?migraine is the mosyndrome and infantile colic is a common cause of infantile cry. the pathogenesis of migraine and colic has not been well established and different factors may cause them. there is an association between infantile colic and the occurrence of childhood migraine. we aimed to assess whether infantile colic could be noted as an early life expression of childhood migraine or not.201728883875
patient outcomes and cerebral infarction after ruptured anterior communicating artery aneurysm treatment.anterior communicating artery aneurysm rupture and treatment is associated with high rates of dependency, which are more severe after clipping compared with coiling. to determine whether ischemic injury might account for these differences, we characterized cerebral infarction burden, infarction patterns, and patient outcomes after surgical or endovascular treatment of ruptured anterior communicating artery aneurysms.201728882863
more fishers and fewer martens due to cumulative effects of forest management and climate change as evidenced from local knowledge.monitoring of fur-bearing species populations is relatively rare due to their low densities. in addition to catch data, trappers' experience provides information on the ecology and status of the harvested species. fisher (pekania pennanti) and american marten (martes americana) are mustelids that are sensitive to forest management and therefore considered to be ecological indicators of forest health. fisher populations have increased in eastern north america since the early 2000s and this could ...201728882186
are orthodontic systematic reviews registered a priori in prospero?aim of this study was to assess the registration of orthodontic systematic reviews in prospero.201728881169
neonatal rat age, sex and strain modify acute antioxidant response to ozone.chronic obstructive pulmonary disease (copd) is the third leading cause of death in the us and its impact continues to increase in women. oxidant insults during critical periods of early life appear to increase risk of copd through-out the life course. to better understand susceptibility to early life exposure to oxidant air pollutants we used fisher (f344), sprague-dawley (sd) and wistar (wis) male and female neonatal rat pups to assess: (a) if strain (i.e. genetics), sex, or stage of early lif ...201728880688
outcome of appendicitis in the elderly in universitas and pelonomi hospitals.in the elderly population, appendicitis still poses a high mortality and morbidity. morbidity rates of 28-60% and mortality rates of 5-10% have been reported. the mortality rate is even higher in the presence of perforated appendicitis. various factors have been pointed out to contribute to this trend.201728876653
[correspondence analysis between traditional commercial specifications and quantitative quality indices of notopterygii rhizoma et radix].this paper aims to explore a comprehensive assessment method combined traditional chinese medicinal material specifications with quantitative quality indicators. seventy-six samples of notopterygii rhizoma et radix were collected on market and at producing areas. traditional commercial specifications were described and assigned, and 10 chemical components and volatile oils were determined for each sample. cluster analysis, fisher discriminant analysis and correspondence analysis were used to est ...201628875629
[analysis of commercial specifications and grades of wild and cultivated gentianae macrophyllae radix based on multi-indicative constituents].the study is aimed to analyze the commercial specifications and grades of wild and cultivated gentianae macrophllae radix based on multi-indicative constituents. the seven kinds of main chemical components containing in gentianae macrophyllae radix were determined by uplc, and then the quality levels of chemical component of gentianae macrophyllae radix were clustered and classified by modern statistical methods (canonical correspondence analysis, fisher discriminant analysis and so on). the qua ...201628875628
one hundred twenty five fat myringoplasties: does marginal perforation matter?to evaluate if calcified plaques adjacent to the perforation and marginal perforations are real contraindications to the fat graft myringoplasty.201728872767
penalized estimation for proportional hazards models with current status data.we provide a simple and practical, yet flexible, penalized estimation method for a cox proportional hazards model with current status data. we approximate the baseline cumulative hazard function by monotone b-splines and use a hybrid approach based on the fisher-scoring algorithm and the isotonic regression to compute the penalized estimates. we show that the penalized estimator of the nonparametric component achieves the optimal rate of convergence under some smooth conditions and that the esti ...201728872695
in-hospital complications following ankle arthrodesis versus ankle arthroplasty: a matched cohort study.ankle arthrodesis has been the traditional surgical treatment for end-stage hindfoot arthritis. however, utilization of total ankle arthroplasty (taa) is increasing as surgical techniques and implants have substantially improved. the purpose of this study was to compare the u.s. national rates of perioperative (in-hospital) complications between a statistically matched cohort of patients who underwent either an ankle arthrodesis or a taa.201728872529
asymptotic confidence intervals for the pearson correlation via skewness and kurtosis.when bivariate normality is violated, the default confidence interval of the pearson correlation can be inaccurate. two new methods were developed based on the asymptotic sampling distribution of fisher's z' under the general case where bivariate normality need not be assumed. in monte carlo simulations, the most successful of these methods relied on the (vale & maurelli, 1983, psychometrika, 48, 465) family to approximate a distribution via the marginal skewness and kurtosis of the sample data. ...201728872186
[clinical efficacy of enhanced recovery after surgery in atrial caval shunting for type ⅱ budd-chiari syndrome].objective: to investigate the clinical efficacy of enhanced recovery after surgery(eras) in atrial caval shunting (acs) for type ⅱ budd-chiari syndrome(bcs). methods: the clinical data of patients underwent acs for type ⅱ bcs in the henan province people's hospital from january 2014 to june 2016 were prospectively analyzed.randomized and single-blind, controlled study was performed among the patients, and all of them underwent acs and were divided into control group (patients underwent tradition ...201728870052
should subclinical hypothyroidism be an exclusion criterion for the diagnosis of polycystic ovary syndrome?the purpose of the study was to examine whether patients with subclinical hypothyroidism (sch) should be excluded before making a diagnosis of polycystic ovary syndrome (pcos).201728868249
personality traits in recent-onset-of-psychosis patients compared to a control sample by gender.personality traits in recent onset of psychosis (rop) patients are an under-researched area. our aim was to examine clinical and clinically significant personality traits in rop patients compared with a healthy control sample by gender. data were obtained from 94 rop patients and a control sample matched in gender and age. the millon clinical multiaxial inventory and a sociodemographic scale were used. t for independent samples, u-mann-whitney and fisher tests were applied to make comparisons. a ...201728867518
effects of patients' affect on adverse procedural events during image-guided interventions.to assess how a patient's affect on presentation relates to the likelihood of adverse events during their subsequent interventional image-guided procedures.201728867310
a multi-modal, discriminative and spatially invariant cnn for rgb-d object labeling.while deep convolutional neural networks have shown a remarkable success in image classification, the problems of inter-class similarities, intra-class variances, the effective combination of multimodal data, and the spatial variability in images of objects remain to be major challenges. to address these problems, this paper proposes a novel framework to learn a discriminative and spatially invariant classification model for object and indoor scene recognition using multimodal rgb-d imagery. thi ...201728866483
frail questionnaire screening tool and short-term outcomes in geriatric fracture patients.there are limited screening tools to predict adverse postoperative outcomes for the geriatric surgical fracture population. frailty is increasingly recognized as a risk assessment to capture complexity. the goal of this study was to use a short screening tool, the frail scale, to categorize the level of frailty of older adults admitted with a fracture to determine the association of each frailty category with postoperative and 30-day outcomes.201728866353
phenograph and visne facilitate the identification of abnormal t-cell populations in routine clinical flow cytometric data.flow cytometric identification of neoplastic t-cell populations is complicated by the wide range of phenotypic abnormalities in t-cell neoplasia, and the diverse repertoire of reactive t-cell phenotypes. we evaluated whether a recently described clustering algorithm, phenograph, and dimensionality-reduction algorithm, visne, might facilitate the identification of abnormal t-cell populations in routine clinical flow cytometric data.201728865188
charlson comorbidity index, inappropriate medication use and cognitive impairment : bermuda triangle.the aim is to evaluate the association between the charlson comorbidity index (cci), polypharmacy, inappropriate medication use and cognitive impairment in long-term care facility patients.201728864869
toxicity and outcomes in patients with and without esophageal stents in locally advanced esophageal cancer.esophageal stenting is often considered to relieve dysphagia in patients with locoregionally advanced esophageal cancer. we sought to determine the effects of stenting on the incidence of acute toxicity and oncologic outcomes in patients undergoing chemoradiation therapy (crt).201728864404
regenerative endodontics versus apexification in immature permanent teeth with apical periodontitis: a prospective randomized controlled study.the aim of the study was to compare the outcomes of regenerative endodontic treatment (ret) and apexification on immature permanent teeth with pulp necrosis and apical periodontitis.201728864219
very early onset inflammatory bowel disease: investigation of the il-10 signaling pathway in iranian children.comparing to adult inflammatory bowel disease (ibd), those with early onset manifestations have different features in terms of the underlying molecular pathology, the course of disease and the response to therapy. we investigated the il-10 signaling pathway previously reported as an important cause of infantile (very early onset) ibd to find any possible variants.201728864178
clinicopathologic and surgical study of pleomorphic adenoma of the parotid gland: analysis of risk factors for recurrence and facial nerve dysfunction.to determine whether clinicopathologic or surgical features are risk factors for recurrence and facial nerve dysfunction in pleomorphic adenoma (pa) of the parotid gland.201728863883
regulation of trophic factor expression by innervating target regions in intraocular double transplants.trophic factors have been found to play a significant role both in long-term survival processes and in more rapid and dynamic processes in the brain and spinal cord. however, little is known regarding the regulation of expression of growth factors, and how these proteins interact on a cell-to-cell basis. we have studied protein levels of one growth factor known to affect the noradrenergic innervation of the hippocampal formation, namely brain-derived neurotrophic factor (bdnf). the purpose of th ...200528863735
isolated abducens nerve palsy associated with subarachnoid hemorrhage: a localizing sign of ruptured posterior inferior cerebellar artery aneurysms.objective compressive cranial nerve syndromes can be useful bedside clues to the diagnosis of an enlarging intracranial aneurysm and can also guide subsequent evaluation, as with an acute oculomotor nerve (cranial nerve [cn] iii) palsy that is presumed to be a posterior communicating artery aneurysm and a surgical emergency until proven otherwise. the cn vi has a short cisternal segment from the pontomedullary sulcus to dorello's canal, remote from most pica aneurysms but in the hemodynamic path ...201728862551
sex differences in delayed cerebral ischemia after subarachnoid hemorrhage.objective in this study the authors sought to investigate the sex differences in the risk of delayed cerebral ischemia (dci), delayed cerebral infarction, and the role of hormonal status. methods ten studies included in the sahit (sah international trialists) repository were analyzed using a fitting logistic regression model. heterogeneity between the studies was tested using i(2) statistics, and the results were pooled using a random-effects model. multivariable analysis was adjusted for the ef ...201728862545
[biological parameters of pseudocurimata boulengeri (characiformes: curimatidae) inhabiting the chongón dam, ecuador].pseudocurimata boulengeri is an endemic species of ecuador, which sustains a large group of fisher families. the biological data of this species correspond to reports from lotic systems of los ríos province; nevertheless, their trend in a lentic system is not yet known. this paper describes the sex ratio, length-weight relationship, gonad development, spawning season and size at reproductive maturity of p. boulengeri, inhabiting the lentic system of chongón dam, ecuador. fish were caught between ...201628862411
refractive changes after lens-sparing vitrectomy for macular hole and epiretinal membrane.cataract progression after lens-sparing vitrectomy might differ according to original posterior segment diseases. our objective was to analyze the refractive values after lens-sparing vitrectomy for macular hole (mh) and epiretinal membrane (erm).201728860703
circumferential trabeculotomy versus conventional angle surgery: comparing long-term surgical success and clinical outcomes in children with primary congenital glaucoma.this study compares the long-term efficacy of circumferential trabeculotomy to that of conventional angle surgeries in primary congenital glaucoma (pcg), as judged by glaucoma and visual outcomes.201728860043
a novel and robust bayesian approach for segmentation of psoriasis lesions and its risk stratification.the need for characterization of psoriasis lesion severity is clinically valuable and vital for dermatologists since it provides a reliable and precise decision on risk assessment. the automated delineation of lesion is a prerequisite prior to characterization, which is challenging itself. thus, this paper has two major objectives: (a) design of a segmentation system which can model by learning the lesion characteristics and this is posed as a bayesian model; (b) develop a psoriasis risk assessm ...201728859832
a probabilistic active learning algorithm based on fisher information ratio.the task of labeling samples is demanding and expensive. active learning aims to generate the smallest possible training data set that results in a classifier with high performance in the test phase. it usually consists of two steps of selecting a set of queries and requesting their labels. among the suggested objectives to score the query sets, information theoretic measures have become very popular. yet among them, those based on fisher information (fi) has the advantage of considering the div ...201728858784
isolated main pancreatic duct dilatation: ct differentiation between benign and malignant causes.the purpose of this study is to retrospectively evaluate the differential ct features of isolated benign and malignant main pancreatic duct (mpd) dilatation and to investigate whether the diagnostic performance of radiologists can be improved with knowledge of these differential ct features.201728858540
spiritual transcendence and psychological adjustment: the moderating role of personality in burn patients.the current study examined the moderating role of personality traits (neuroticism and extraversion) on the relationship between spiritual transcendence and positive change, and spiritual transcendence and distress in burn patients. the sample (n = 98) comprised adult burn patients (age = 25-50) admitted to three hospitals in lahore, pakistan. they were assessed according to a demographic information sheet, the neo personality inventory (mccrae and costa in j personal soc psychol 52:81-90, 1987), ...201728856506
a new sensitive automated assay for procalcitonin detection: liaison(®) brahms pct(®) ii gen.to assess the performance of liaison(®) brahms pct(®) ii gen (diasorin, saluggia, italy) in procalcitonin (pct) determination by comparing it to the assay reference method b·r·a·h·m·s pct kryptor (thermo fisher scientific clinical diagnostics, hennigsdorf, germany) and assessing its ability to discriminate between healthy subjects and patients with suspected infection.201628856207
hirschsprung disease diagnosis: calretinin marker role in determining the presence or absence of ganglion cells.hirschsprung disease is a complex genetic disorder of the enteric nervous system (ens), often called congenital aganglionic megacolon and characterized by the absence of enteric neurons along a variable length of the intestine. the definitive diagnosis of hirschsprung disease relies on histologic and/or histochemical staining of sections from suction rectal biopsies. calretinin immunohistochemistry (ihc) may be a useful in its diagnosis. this study aimed to proof the usefulness of immunohistoche ...201628855933
higher flow is present in unruptured arteriovenous malformations with silent intralesional microhemorrhages.silent microhemorrhage (hemosiderin) has been observed in resected brain arteriovenous malformations (bavm) tissue and may represent a subgroup at increased risk for clinical hemorrhage. previous studies suggest that ruptured bavms have faster flow and shorter mean transit time of contrast in blood vessels than unruptured bavms. we hypothesized that flow would be faster in unruptured avms with hemosiderin compared with those without hemosiderin.201728855391
differentiation of hepatocellular carcinoma from other hepatic malignancies in patients at risk: diagnostic performance of the liver imaging reporting and data system version 2014.purpose to evaluate the diagnostic performance and interrater reliability of the liver imaging reporting and data system (li-rads) version 2014 in differentiating hepatocellular carcinoma (hcc) from non-hcc malignancy in a population of patients at risk for hcc. materials and methods this retrospective hipaa-compliant institutional review board-approved study was exempt from informed consent. a total of 178 pathology-proven malignant liver masses were identified in 178 patients at risk for hcc b ...201728853673
isolated single umbilical artery and fetal echocardiography: a 25-year experience at a tertiary care city hospital.to review our 25-year experience with a single umbilical artery and fetal echocardiography to estimate the need for this test in cases of an isolated single umbilical artery.201728850695
utility and safety of repeated ultrasound-guided core needle biopsy of focal liver masses.to evaluate the accuracy and safety of repeated ultrasound-guided core needle biopsy (cnb) for hepatic focal lesions and to assess the predictive factors for success of repeated cnb.201728850692
risk factors associated with neural tube defects in infants referred to western iranian obstetrical centers; 2013-2014.neural tubes defects (ntds) are known to be the second most prevalent congenital disorder worldwide whose risk factors have not been explicitly addressed yet.201728848641
utilisation of early intervention services in young children with hypoplastic left heart syndrome.children with hypoplastic left heart syndrome are at a risk for neurodevelopmental delays. current guidelines recommend systematic evaluation and management of neurodevelopmental outcomes with referral for early intervention services. the single ventricle reconstruction trial represents the largest cohort of children with hypoplastic left heart syndrome ever assembled. data on life events and resource utilisation have been collected annually. we sought to determine the type and prevalence of ear ...201728847329
the future of tissue engineering and regenerative medicine in africa.following the successful hosting of the first international conference on tissue engineering and regenerative medicine (icterm) in 2014, we are delighted to report that the second icterm in 2017 was a greater success. the conference was held in vanderbijlpark, south africa, july 26-30, 2017 and was co-hosted by the vaal university of technology, tshwane university of technology of south africa, and rice university of the usa. the conference was attended by policy makers as well as distinguished ...201728847204
prevalence of the mthfr c677t mutation in fertile and infertile women.introduction the importance of the c677t mutation in the methylenetetrahydrofolate reductase (mthfr) gene in infertile women remains controversial. objective to evaluate if the mthfr c677t mutations are more frequent in infertile women, and if they can be associated with the occurrence of infertility in the brazilian population. methods this case-control study included 130 infertile women consulting at a private clinic between march 2003 and march 2005 (data previously published), and 260 fertil ...201728847029
association between preoperative cardiac left ventricular dysfunction and perioperative intraaortic balloon pump in patients undergoing off-pump coronary artery bypass surgery.prophylactic use of intraaortic balloon pump (iabp) reduces hospital mortality in patients with left ventricular (lv) systolic dysfunction undergoing coronary artery bypass surgery (cabg); however, its association in patients with lv diastolic dysfunction is unclear. this retrospective study investigated the association between preoperative lv function and perioperative use of iabp in patients undergoing off-pump cabg (opcab) at a university hospital.201728846529
[early diagnosis of risk for developing calcium oxalate urolithiasis].to identify risk groups for calcium oxalate urolithiasis among healthy individuals and patients with urolithiasis in the russian population using molecular genetics.201728845932
clinical evidence for regenerative endodontic procedures: immediate versus delayed induction?clinicians face many challenges when treating immature permanent teeth in young patients. immediate blood clot induction can be a successful option as described by some case reports. no experimental studies or clinical trials have addressed this question. we have designed a clinical trial in which we hypothesized that there is no difference in success between immediate or delayed induction protocols. after confirmation of pulpal necrosis, patients were randomized. in the delayed group, 15 teeth ...201728844307
the effect of glass fiber posts and ribbons on the fracture strength of teeth with flared root canals restored using composite resin post and cores.this study evaluated the fracture strength and mode of failure of structurally compromised teeth with flared root canals restored using composite resin with four different systems.201728843642
prevalence of borrelia miyamotoi and borrelia burgdorferi sensu lato in questing ticks from a recreational coniferous forest of east saxony, germany.the hard tick ixodes ricinus is the most important vector of tick-transmitted pathogens in europe, frequently occurring in urban parks and greenbelts utilized for recreational activities. this species is the most common vector of the causative agents of lyme borreliosis in europe. similarly, the species spreads borrelia miyamotoi, causing a relapsing-fever like illness. a total of 1774 ixodes ricinus (50 females, 68 males, 840 nymphs and 818 larvae) were collected with flagging between march and ...201728843481
relationship between vitamin d deficiency and markers of metabolic syndrome among overweight and obese adults.in recent years, metabolic syndrome, obesity, diabetes and cardiovascular disease has had a tremendous elevation growth. many studies have demonstrated negative correlation between vitamin d deficiency and indexes of metabolic syndrome in obese patients. this study was designed to find the relation between vitamin d deficiency and markers of metabolic syndrome among overweight and obese adults referred to obesity center of shahid sadoughi hospital in 2014. eighty-nine overweight and obese adults ...201728843242
evaluation of the precision id identity panel for the ion torrent(™) pgm(™) sequencer.in cases where only a partial or incomplete str profile is obtained from a sample, information contained in single nucleotide polymorphisms (snps) can prove informative for human identification. thermo fisher scientific, which developed the high throughput ion torrent(™) pgm(™) sequencer, released the precision id identity panel, a multiplex snp panel for human identity. we evaluated the reproducibility and sensitivity of this multiplex, which contains primers for the amplification of 90 autosom ...201728843089
factors predicting ventricle volume increase after aneurysmal clipping in patients with subarachnoid hemorrhage.while many studies have evaluated risk factors associated with hydrocephalus after aneurysmal subarachnoid hemorrhage, specific ventricle volume changes after subarachnoid hemorrhage have not been evaluated. to evaluate factors predicting ventricle volume enlargement in patients with aneurysmal subarachnoid hemorrhage by measuring ventricle volume with a validated semi-automated tool.201728842230
[development of tianma hplc fingerprint and discriminant analysis].tianma(the tuber of gastrodia eleta) is a widely used and pricy chinese herb. its counterfeits are often found in herbal markets, which are the plant materials with similar macroscopic characteristics of tianma. moreover, the prices of winter tianma(cultivated tianma) and spring tianma(mostly wild tianma) have significant difference. however, it is difficult to identify the true or false, good or bad quality of tianma samples. thus, a total of 48 tianma samples with different characteristics(inc ...201728840694
identifying pleiotropic genes in genome-wide association studies from related subjects using the linear mixed model and fisher combination function.a multivariate genome-wide association test is proposed for analyzing data on multivariate quantitative phenotypes collected from related subjects. the proposed method is a two-step approach. the first step models the association between the genotype and marginal phenotype using a linear mixed model. the second step uses the correlation between residuals of the linear mixed model to estimate the null distribution of the fisher combination test statistic.201728836938
commentary: the importance of exploring dose-dependent, subtype-specific, and age-related effects of maltreatment on the hpa axis and the mediating link to psychopathology. a response to fisher (2017).we greatly appreciate dr. fisher's commentary that provides an excellent backdrop and well-considered perspective on our findings. we agree that our results mesh well with previous work documenting hypocortisolism among youth who experienced early adversity, especially neglect. moreover, as also perceptively noted by dr. fisher, our cross-sectional data provide support for the notion that hypocortisolism is not simply a transient phenomenon, but, rather, a persistent pattern characterizing maltr ...201728836675
the coexistence of psychiatric and gastrointestinal problems in children with restrictive eating in a nationwide swedish twin study.restrictive eating problems are rare in children but overrepresented in those with neurodevelopmental problems. comorbidities decrease wellbeing in affected individuals but research in the area is relatively scarce. this study describes phenotypes, regarding psychiatric and gastrointestinal comorbidities, in children with restrictive eating problems.201728835820
the changing epidemiological characteristics of severe fever with thrombocytopenia syndrome in china, 2011-2016.severe fever with thrombocytopenia syndrome (sfts) is emerging and the number of sfts cases increased year by year in china. in order to explore the epidemiology trend, we analyzed the changing epidemiological characteristics of sfts cases in different years and compare characteristics in different provinces. from 2011 to 2016, a total of 5360 laboratory-confirmed sfts cases were reported and annual case numbers increased year by year. most sfts cases occurred in individuals aged between 40 year ...201728835633
paranasal sinus disease in children with headache.sinus headache is one of the most frequent misdiagnosis given to children with headache. the objective of this study is to evaluate the frequency of sinus disease in children with headache that do not fulfill the criteria for headache attributed to disorder of the nose or paranasal sinuses.201728831857
increased plasma galectin-3 preceding the development of delayed cerebral infarction and eventual poor outcome in non-severe aneurysmal subarachnoid hemorrhage.a matricellular protein galectin-3 is involved in tissue injury and inflammation, but the role of galectin-3 remains unclear in aneurysmal subarachnoid hemorrhage (sah). the purpose of this study was to assess whether acute-stage galectin-3 levels were associated with the subsequent development of neurovascular events and outcome after sah. this study included 83 consecutive patients diagnosed with aneurysmal sah of resuscitated world federation of neurological surgeons (wfns) grades 1-3. plasma ...201728831694
feature ranking and rank aggregation for automatic sleep stage classification: a comparative study.nowadays, sleep quality is one of the most important measures of healthy life, especially considering the huge number of sleep-related disorders. identifying sleep stages using polysomnographic (psg) signals is the traditional way of assessing sleep quality. however, the manual process of sleep stage classification is time-consuming, subjective and costly. therefore, in order to improve the accuracy and efficiency of the sleep stage classification, researchers have been trying to develop automat ...201728830438
anatomic reasons for failure to visualize the appendix with graded compression sonography: insights from contemporaneous ct.the purpose of this study is to identify the anatomic locations of appendixes on ct when graded compression sonography fails to visualize the appendix.201728829172
programmed death ligand-1 (pd-l1) expression in either tumor cells or tumor-infiltrating immune cells correlates with solid and high-grade lung adenocarcinomas.- programmed death ligand-1 (pd-l1) expression in non-small cell lung carcinoma (nsclc) is heterogeneous and known to be underestimated on small biopsies. correlation of pd-l1 expression with clinicopathologic features may provide additional useful information. to our knowledge, the clinicopathologic features of nsclc have not been reported for subsets defined by pd-l1 expression in either tumor cells or tumor-infiltrating immune cells.201728829153
the xp-endo finisher for the removal of calcium hydroxide paste from root canals and from the apical third.the aim was to compare the efficacy of the passive ultrasonic irrigation pui and the xp-endo finisher (fkg-dentaire, la-chaux-de-fonds, switzerland) in removing the calcium hydroxide paste from root canals and from the apical third.201728828150
risk factors for erectile dysfunction in men with htlv-1.erectile dysfunction (ed) occurs in more than 50% of patients with human t-cell lymphotropic virus type 1 (htlv-1) infection. in the general population, atherosclerosis is the main risk factor related to ed.201728827086
diagnostic performance of ultrasonography for pediatric appendicitis: a night and day difference?for imaging pediatric appendicitis, ultrasonography (us) is preferred because of its lack of ionizing radiation, but is limited by operator dependence. this study investigates the us diagnostic performance during night shifts covered by radiology trainees compared to day shifts covered by attending radiologists.201728826614
analysis of ancestry informative markers in three main ethnic groups from ecuador supports a trihybrid origin of ecuadorians.ancestry inference is traditionally done using autosomal snps that present great allele frequency differences among populations from different geographic regions. these ancestry informative markers (aims) are useful for determining the most likely biogeographic ancestry or population of origin of an individual. due to the growing interest in aims and their applicability in different fields, commercial companies have started to develop aim multiplexes targeted for massive parallel sequencing plat ...201728826061
macrophage migration inhibitory factor as a serum prognostic marker in patients with aneurysmal subarachnoid hemorrhage.macrophage migration inhibitory factor (mif) has been implicated in inflammation. we clarified whether serum mif could be used as a marker of inflammation, brain damage and outcome after aneurysmal subarachnoid hemorrhage (asah).201728823650
porcine dermis patch augmentation of supraspinatus tendon repairs: a pilot study assessing tendon integrity and shoulder function 2 years after arthroscopic repair in patients aged 60 years or older.to investigate the 2-year postoperative clinical and subjective outcomes after arthroscopic rotator cuff repair (arcr) with xenologous porcine dermal patch augmentation compared with arcr alone.201728822637
impact of processing methods on urinary biomarkers analysis in neonates.in neonates, the validation of urinary biomarkers to diagnose acute kidney injury is a rapidly evolving field. the neonatal population poses unique challenges when assessing the collection, storage, and processing of urinary samples for biomarker analysis. given this, establishing optimal and consistent sample processing in this population for meaningful use in ongoing clinical trials is important.201728821985
transcriptomic and epigenetic regulation of disuse atrophy and the return to activity in skeletal muscle.physical inactivity and disuse are major contributors to age-related muscle loss. denervation of skeletal muscle has been previously used as a model with which to investigate muscle atrophy following disuse. although gene regulatory networks that control skeletal muscle atrophy after denervation have been established, the transcriptome in response to the recovery of muscle after disuse and the associated epigenetic mechanisms that may function to modulate gene expression during skeletal muscle a ...201728821632
il-17a deficiency mitigates bleomycin-induced complement activation during lung fibrosis.interleukin 17a (il-17a) and complement (c') activation have each been implicated in the pathogenesis of idiopathic pulmonary fibrosis (ipf). we have reported that il-17a induces epithelial injury via tgf-β in murine bronchiolitis obliterans; that tgf-β and the c' cascade present signaling interactions in mediating epithelial injury; and that the blockade of c' receptors mitigates lung fibrosis. in the present study, we investigated the role of il-17a in regulating c' in lung fibrosis. microarra ...201728821630
association between patient factors and outcome of synthetic cartilage implant hemiarthroplasty vs first metatarsophalangeal joint arthrodesis in advanced hallux rigidus.we evaluated data from a clinical trial of first metatarsophalangeal joint (mtpj1) implant hemiarthroplasty and arthrodesis to determine the association between patient factors and clinical outcomes.201728820949
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