osteomyelitis caused by neosartorya pseudofischeri.the first case of osteomyelitis caused by neosartorya pseudofischeri is reported. the patient, a 77-year-old male with a history of silicosis and tuberculosis, on x-ray examination revealed lytic lesions of l2 and l3 vertebrae suspicious for metastatic lesions. histologic examination of biopsy specimens from vertebral bodies showed short, distorted, extra- and intracellular, hyaline hyphal fragments. the culture from the biopsy tissue produced numerous, evanescent asci containing eight ellipsoid ...19947852580
isolation of neosartorya pseudofischeri from blood: first hint of pulmonary aspergillosis.we report a case of invasive pulmonary aspergillosis caused by neosartorya pseudofischeri s. w. peterson [anamorph aspergillus thermomutatus (paden) s. w. peterson]. the diagnosis was initially based on a positive blood culture for a strain isolated from a neutropenic patient by means of a bactec 9050 blood culture system. the final diagnosis was established based on x-ray and computer tomography scan results as well as the detection of aspergillus antigen in the patient's serum.200414766893
mistaken identity: neosartorya pseudofischeri and its anamorph masquerading as aspergillus fumigatus.invasive fungal infections caused by neosartorya pseudofischeri s. w. peterson [anamorph aspergillus thermomutatus (paden) s. w. peterson] are extremely rare. phenotypically, the anamorphic state of n. pseudofischeri resembles aspergillus fumigatus, the predominant agent of invasive aspergillosis in immunocompromised hosts. we report the recovery of three clinical isolates of n. pseudofischeri, all initially misidentified by morphological characteristics as a. fumigatus. all three isolates were ...200516333088
aspergillus section fumigati: antifungal susceptibility patterns and sequence-based identification.this study analyzed 28 aspergillus strains belonging to the section fumigati that were isolated from clinical samples in spain. all isolates sporulated slowly and were unable to grow at 48 degrees c. phylogenetic analysis based on sequencing of partial sequences of the beta-tubulin and rodlet a genes was used to classify the 28 strains into six different clades (neosartorya hiratsukae, neosartorya pseudofischeri, aspergillus viridinutans, aspergillus lentulus, aspergillus fumigatiaffinis, and as ...200818212093
peritonitis due to neosartorya pseudofischeri in an elderly patient undergoing peritoneal dialysis successfully treated with voriconazole.aspergillus peritonitis is a rare life-threatening complication of peritoneal dialysis (pd). we report a case of symptomatic neosartorya pseudofischeri peritonitis in a 60-year-old woman treated by continuous ambulatory peritoneal dialysis (capd) for 13 months, who performed peritoneal exchanges independently. this is believed to be the first published case of n. pseudofischeri in an elderly patient. comprehensive treatment included early removal of the pd catheter and the use of voriconazole (2 ...200919369533
unusual aspergillus species in patients with cystic fibrosis.poorly sporulating aspergillus isolates from patients with cystic fibrosis (cf) are generally identified in routine procedures as aspergillus spp. in this study, we identified and characterized 11 isolates belonging to two unusual aspergillus species of the section fumigati (a. lentulus and neosartorya pseudofischeri) recovered from four different patients. aspergillus lentulus was found occasionally during a 10-year follow-up study of one cf patient colonized by a. fumigatus. neosartorya pseudo ...201021067321
rapid identification of aspergillus fumigatus within the section fumigati.abstract:201121510879
multi-resistant aspergillosis due to cryptic species.reports of cryptic species causing aspergillosis in humans are increasing in the literature. cryptic species are defined as those which are morphologically indistinguishable, although their identifications can be confirmed using molecular or other techniques which continue to become more widely available in the clinical setting. antifungal resistance has often been noted in these cases, and indeed there does appear to be a higher prevalence of reduced susceptibility in cryptic species. many of t ...201424969615
aspergillus fumigatus-related species in clinical practice.aspergillus fumigatus is the main etiologic agent of invasive aspergillosis (ia). other aspergillus species belonging to the section fumigati (a. fumigatus complex) may occasionally be the cause of ia. these strains are often misidentified, as they cannot be distinguished from a. fumigatus by conventional morphological analysis and sequencing methods. this lack of recognition may have important consequences as these a. fumigatus-related species often display some level of intrinsic resistance to ...201627242710
diversity and specificity of microsatellites within aspergillus section fumigati.microsatellites (or short tandem repeats, strs) are the genetic markers of choice for studying aspergillus fumigatus molecular epidemiology due to its reproducibility and high discrimination power. however, the specificity of these markers must be investigated in a group of isolates from closely related species. the aim of this work was to test a microsatellite-based pcr multiplex previously designed for a. fumigatus in a set of species belonging to section fumigati, namely aspergillus fumigatia ...201222838495
detection of aspergillus-specific antibodies by agar gel double immunodiffusion and igg elisa in feline upper respiratory tract aspergillosis.feline upper respiratory tract aspergillosis (urta) is an emerging infectious disease. the aims of this study were: (1) to assess the diagnostic value of detection of aspergillus-specific antibodies using an agar gel double immunodiffusion (agid) assay and an indirect immunoglobulin g (igg) elisa; and (2) to determine if an aspergillin derived from mycelia of aspergillus fumigatus, aspergillus niger and aspergillus flavus can be used to detect serum antibodies against cryptic aspergillus spp. in ...201525634077
misidentification of neosartorya pseudofischeri as aspergillus fumigatus in a lung transplant patient.we present a case of disseminated neosartorya pseudofischeri infection in a bilateral lung transplant patient with cystic fibrosis. the organism was originally misidentified from respiratory specimens as aspergillus fumigatus using colonial and microscopic morphology. dna sequencing subsequently identified the organism correctly as n. pseudofischeri.201424829237
restriction analysis of an amplified roda gene fragment to distinguish aspergillus fumigatus var. ellipticus from aspergillus fumigatus var. fumigatus.a previous multidisciplinary study indicated that gliotoxin-producing aspergillus fumigatus fresen. isolates from silage commodities mostly belonged to its variant a. fumigatus var. ellipticus raper & fennell. sequence analysis revealed the presence of a single nucleotide polymorphism at five positions in a fragment of the roda gene (coding for a hydrophobin rodleta protein) between aspergillus fumigatus var. fumigatus and aspergillus fumigatus var. ellipticus. a method was developed to distingu ...201222670589
screening of thermotolerant and thermophilic fungi aiming β-xylosidase and arabinanase production.plant cell wall is mainly composed by cellulose, hemicellulose and lignin. the heterogeneous structure and composition of the hemicellulose are key impediments to its depolymerization and subsequent use in fermentation processes. thus, this study aimed to perform a screening of thermophilic and thermotolerant filamentous fungi collected from different regions of the são paulo state, and analyze the production of β-xylosidase and arabinanase at different temperatures. these enzymes are important ...201425763055
aspergilli with neosartorya-type ascospores: heat resistance and effect of sugar concentration on growth and spoilage incidence in berry products.this study focused on four different heat resistant aspergilli: two strains of aspergillus hiratsukae (≡neosartorya hiratsukae), one strain of aspergillus neoglaber (≡neosartorya glabra), and one strain of aspergillus thermomutatus (≡neosartorya pseudofischeri), all isolated from spoiled pasteurized products. their heat-resistance, the sugar concentration limiting their germination and growth in berry-based media, and a possible relation between the contamination levels of the raw materials used ...201728772258
cryptic and rare aspergillus species in brazil: prevalence in clinical samples and in vitro susceptibility to triazoles.aspergillus spp. are among the most common causes of opportunistic invasive fungal infections in tertiary care hospitals. little is known about the prevalence and in vitro susceptibility of aspergillus species in latin america, because there are few medical centers able to perform accurate identification at the species level. the purpose of this study was to analyze the distribution of cryptic and rare aspergillus species among clinical samples from 133 patients with suspected aspergillosis admi ...201425078909
five new cytotoxic metabolites from the marine fungus neosartorya pseudofischeri.the marine fungus neosartorya pseudofischeri was isolated from acanthaster planci from the south china sea. in a preliminary bioactivity screening, the crude methanol extract of the fungal mycelia showed significant inhibitory activity against the sf9 cell line from the fall armyworm spodoptera frugiperda. five novel compounds, including 5-olefin phenylpyropene a (1), 13-dehydroxylpyripyropene a (4), deacetylsesquiterpene (7), 5-formyl-6-hydroxy-8-isopropyl-2- naphthoic acid (9) and 6,8-dihydrox ...201626771621
exploring the chemodiversity and biological activities of the secondary metabolites from the marine fungus neosartorya pseudofischeri.the production of fungal metabolites can be remarkably influenced by various cultivation parameters. to explore the biosynthetic potentials of the marine fungus, neosartorya pseudofischeri, which was isolated from the inner tissue of starfish acanthaster planci, glycerol-peptone-yeast extract (glypy) and glucose-peptone-yeast extract (glupy) media were used to culture this fungus. when cultured in glypy medium, this fungus produced two novel diketopiperazines, neosartins a and b (1 and 2), toget ...201425421322
successful treatment of aspergillus peritonitis in a peritoneal dialysis patient.aspergillus peritonitis is a rare, potentially fatal complication of continuous ambulatory peritoneal dialysis (capd). we report the successful treatment of refractory fungal peritonitis in an 8-year-old girl treated by peritoneal dialysis for 3.3 years. this is the second report of aspergillus thermomutatus(telemorph: neosartorya pseudofischeri) in humans. comprehensive treatment included early removal of the capd catheter, the use of liposomal amphotericin b, and the use of itraconazole.200211956874
secondary metabolites from a culture of the fungus neosartorya pseudofischeri and their in vitro cytostatic activity in human cancer cells.four known (1, 2, 3, and 6) and three new compounds including a 1,4-diacetyl-2,5-dibenzylpiperazine derivative (4), a quinazolinone-containing indole derivative (5), and a new ester of 2,4-dihydroxy-6-methylbenzoic acid (7) were isolated from the fungus neosartorya pseudofischeri s. w. peterson. compound 2 displayed in vitro growth inhibitory activity that ranged between the activities of etoposide and carboplatin, chosen as reference compounds, in six distinct cancer cell lines. compound 1 disp ...201222976482
invasive mould disease involving the gastrointestinal tract caused by neosartorya pseudofischeri in a haematological patient. 201323356572
neosartorya pseudofischeri cellulitis in an extremely low birth weight preterm baby. 201525280780
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