Publications

TitleAbstractYear
Filter
PMID
Filter
bacillary angiomatosis. clinical and histologic features, diagnosis, and treatment.bacillary angiomatosis is a relatively new infection affecting primarily patients with human immunodeficiency virus or others with impaired host defenses. it presents most commonly with multiple red skin lesions, but visceral involvement may also occur, including involvement of the liver and spleen. because of the dermatologic manifestations, bacillary angiomatosis may be mistaken for kaposi's sarcoma. the diagnosis is made by identification of the characteristic histologic findings or genetic a ...19948122945
rochalimaea henselae infections: newly recognized zoonoses transmitted by domestic cats. 19948144389
rochalimaea henselae organisms possess an elevated capacity of binding to peripheral blood lymphocytes from patients with cat scratch disease.cat scratch disease (csd) is a clinical condition whose aetiological agent, according to recent findings, is of bacterial origin. two gram-negative bacteria are invoked as causative agents of csd, namely afipia felis and rochalimaea henselae. in this paper, five patients with suspected csd were studied in terms of binding capacity of a. felis and r. henselae to their own peripheral blood lymphocytes (pbl). this parameter was correlated with serum antibody titres to both a. felis and r. henselae, ...19948152395
atypical cat-scratch disease: diagnosis by a serologic test for rochalimaea species.three patients with atypical manifestations of cat-scratch disease (csd) had the diagnosis supported by a newly available serologic assay for antibodies to rochalimaea henselae. previously, csd has been a diagnosis of exclusion because no confirmatory test was readily available. atypical or severe cases of csd have often required detailed (and expensive) clinical and laboratory investigation. the use of rochalimaea-specific serologic tests may help avoid extensive diagnostic testing or invasive ...19948153776
bacillary angiomatosis of the spleen.bacillary angiomatosis is a recently described vasoproliferative lesion associated with infection by a newly characterized rickettsial organism, rochalimaea henselae. most previous reports have described skin lesions in immunocompromised patients infected with human immunodeficiency virus. this is the first case report detailing the features of bacillary angiomatosis of the spleen occurring in a patient undergoing cytotoxic chemotherapy for disseminated ovarian carcinoma.19938165007
neuroretinitis, aseptic meningitis, and lymphadenitis associated with bartonella (rochalimaea) henselae infection in immunocompetent patients and patients infected with human immunodeficiency virus type 1.bartonella (rochalimaea) henselae causes a variety of diseases, including bacillary angiomatosis, peliosis hepatis, lymphadenitis, aseptic meningitis with bacteremia, and cat-scratch disease (csd). cases of b. henselae-related disease were collected from september 1991 through november 1993. patients with suspected csd, unexplained fever and lymphadenitis, or suspected b. henselae infection who were seen in the infectious diseases clinic at wilford hall medical center (lackland air force base, t ...19958562744
[bartonella (rochalimaea) infections: cat-scratch disease and bacillary angiomatosis]. 19968565812
intracellular location of bartonella henselae cocultivated with vero cells and used for an indirect fluorescent-antibody test.bartonella henselae, the major causative agent of cat scratch disease, was cocultivated with vero cells on chamber slides and visualized by indirect immunofluorescence by using a patient serum containing specific antibodies. confocal microscopy localized the granular b. henselae-specific fluorescence mainly around the nuclei of vero cells. by transmission electron microscopy, these granules were identified as clusters of multiple intracellular organisms. fixed slides with the monolayers of vero ...19958574831
cat-scratch disease simulating lymphoma. 19968576472
serology to bartonella (rochalimaea) henselae may replace traditional diagnostic criteria for cat-scratch disease.bartonella (rochalimaea) henselae has been identified as causative agent of cat-scratch disease (csd). employing an indirect fluorescence antibody test we found that 20 (100%) out of 20 children with suspected csd had serum titres to b. henselae of > or = 512. by contrast, in all but one of the controls (n = 332) including subjects exposed to the same cats, patients with diseases other than csd, and blood donors the antibody titres were < or = 256 (p < 0.001). however, significant regional diffe ...19958582404
cat-scratch disease, bartonella henselae, and the usefulness of routine serological testing for afipia felis. 19958645822
[cat scratch disease caused by bartonella henselae].bartonella henselae is an etiologic agent of cat-scratch disease and, in immunocompromised patients, of bacillary angiomatosis and other severe syndromes. cat-scratch disease usually presents as lymphadenopathy, which resolves spontaneously within 2-4 months. the utility of antibiotic therapy remains controversial. in tyrol four cases of human cat-scratch disease were diagnosed in children in 1994, yielding a prevalence of 0.7/100,000 per year. a 3-year-old boy had lymphadenitis coli since one y ...19958582740
detection of rochalimaea henselae in cat-scratch disease skin test antigens.one of the diagnostic criteria for cat-scratch disease is a positive delayed-type hypersensitivity skin test reaction to an antigen prepared from purulent material aspirated from a cat-scratch disease-involved lymph node. polymerase chain reaction coupled with dna sequence analysis was used to identify organisms found in these skin test antigen preparations that may be responsible for eliciting this response. two independent sources of cat-scratch disease skin test antigens yielded dna sequences ...19938376816
endocarditis caused by rochalimaea henselae.a case of community-acquired, culture-negative, infective endocarditis was diagnosed in a 57-year-old construction worker. small, pleomorphic gram-negative rods were seen in brown-hopps tissue gram stains and warthin-starry silver stains. the organism was identified as rochalimaea henselae by polymerase chain reaction amplification and sequencing of the 16s rdna gene sequence. this is the first report of infective endocarditis caused by r henselae.19938406424
bacteremia due to rochalimaea henselae in a child: practical identification of isolates in the clinical laboratory.two closely related species of rochalimaea, rochalimaea quintana and rochalimaea henselae, are nutritionally fastidious but can be cultivated on bacteriologic media from the blood of patients with diverse clinical presentations. we report a case of culture-proven r. henselae bacteremia in a child with persistent fever. serologic evidence of infection by r. henselae was ascertained by testing sera at two intervals for immunoglobulin g or immunoglobulin m antibodies by enzyme immunoassay and immun ...19938408560
syndrome of rochalimaea henselae adenitis suggesting cat scratch disease.to describe a clinical syndrome of cat scratch disease caused by rochalimaea henselae, including methods for isolation of the organism from tissue and for identification.19938430978
endocarditis caused by rochalimaea quintana in a patient infected with human immunodeficiency virus.rochalimaea quintana and rochalimaea henselae are closely related, fastidious, gram-negative rickettsiae. thus far, the spectrum of human rochalimaea sp. infections has not included endocarditis. we describe a 50-year-old human immunodeficiency virus-positive man who developed endocarditis caused by r. quintana. dna relatedness studies, which compared our patient's blood culture isolate with known rochalimaea species, identified the organism as r. quintana. our report expands the spectrum of roc ...19938458964
eia for detection of rochalimaea henselae-reactive igg, igm, and iga antibodies in patients with suspected cat-scratch disease. 19938501350
[rochalimaea henselae infection. febrile pancytopenia and hepatic peliosis in a patient with hiv infection].a case of rochalimaea henselae infection in an aids patient is reported. the r. henselae infection was revealed by febrile pancytopenia associated with liver and spleen enlargement. the diagnosis was made on the finding at histology of hepatic peliosis lesions. within these lesions warthin starry staining displayed bacilli that were identified as r. henselae. this case shows that all hiv-infected patients with these symptoms might be infected with this organism.19938511079
fever, abdominal pain and an intracranial mass. 19958532442
lack of bactericidal effect of antibiotics except aminoglycosides on bartonella (rochalimaea) henselae.bartonella (rochalimaea) henselae is a cause of peliosis hepatis and bacillary angiomatosis, and one of the putative agents of cat scratch disease. specific therapy for b. henselae infections is not available. treatment failures and relapses are frequent, especially following brief antibiotic courses, and this contrasts with the in-vitro susceptibility of b. henselae to most antibiotics. we decided to test the antibiotic susceptibility of b. henselae associated with murine macrophage-like cells ...19958537257
[encephalopathy in cat scratch disease]. 19958545389
imaging manifestations of cat-scratch disease.cat-scratch disease affects an estimated 22,000 people in the united states each year, more than half of whom are children or adolescents [1]. it is caused by bartonella henselae, a gram-negative bacillus usually introduced by the scratch of a cat [2]. in the past, diagnosis was made if three of the following four criteria were met: (1) history of cat exposure with inoculation, (2) positive skin test: (3) absent laboratory and histopathologic evidence of other diseases, and (4) biopsy findings o ...19968553962
granulomatous hepatitis and necrotizing splenitis due to bartonella henselae in a patient with cancer: case report and review of hepatosplenic manifestations of bartonella infection.bacillary angiomatosis and the related disorders of bacillary peliosis hepatis and bacillary splenitis are manifestations of infection with bartonella henselae and bartonella quintana in immunocompromised persons. b. henselae infection, but not b. quintana infection, is linked to contact with cats and is presumed to cause visceral cat-scratch disease. we reports a case of visceral infection by b. henselae in an adult patient with cancer who was receiving chemotherapy and had had no contact with ...19968783692
cat-scratch disease: single or multiple causative microorganisms? 19958559644
cluster of five children with acute encephalopathy associated with cat-scratch disease in south florida.between august 12 and september 27, 1994, five children in south florida were hospitalized at a single hospital because of encephalopathy, presenting as status epilepticus, associated with cat-scratch disease (csd). diagnoses were confirmed by using an indirect fluorescent antibody test to detect antibody to bartonella henselae, the causative agent of csd. these cases represent the first cluster of csd encephalopathy cases to be recognized in the united states. the patients lived within 7 miles ...19958584313
prolonged bartonella bacteremia in cats associated with cat-scratch disease patients.recent evidence supports a causal relationship between bartonella (rochalimaea) henselae, cat-scratch disease (csd), and bacillary angiomatosis. cats appear to be the primary reservoir. blood from 19 cats owned by 14 patients diagnosed with csd was cultured. blood samples from cats owned by veterinary students (n = 25) having no association with csd or bacillary angiomatosis were cultured as controls. eighty-nine percent (17 of 19) of cats associated with csd patients and 28% (7 of 25) of contro ...19958586710
bartonella henselae is a causative agent of cat scratch disease in australia.we report the first isolation of bartonella henselae from the blood and fleas of a cat of a patient with cat scratch disease (csd) in australia. a 49-year-old man presented with a history that 3 weeks after he had removed fleas from his cat he had developed fever, lethargy and anorexia for 3 days. this was followed by the appearance of axillary lymphadenopathy. there was no history of a bite or scratch and no primary lesion on the skin. two fine needle aspirates of the axillary lymph node showed ...19958586847
cat-scratch disease diagnosed serologically using an enzyme immunoassay in a patient with neuroretinitis. 19968602794
seroprevalence to bartonella quintana among patients at a community clinic in downtown seattle.in 1993, an outbreak of 10 cases of bartonella quintana bacteremia occurred among homeless, alcoholic, human immunodeficiency virus (hiv)-negative persons in seattle. to estimate the prevalence of past exposure b. quintana among this population, a serosurvey was conducted in 1994 among patients at a downtown seattle clinic. microimmunofluorescent titers to b. quintana in 192 clinic patients were compared with titers in 199 age- and sex-matched seattle volunteer blood donors. titers > or = 64 wer ...19968603944
[cat-scratch disease and other infections caused by bartonella species].bartonella henselae, the causative agent of cat-scratch disease, was identified recently by dna amplification techniques. several other bartonellae (most of which were called rochalimaea before) cause disease in humans: b. bacilliformis (carrion's disease), b. elizabethae (endocarditis) and b. quintana (bacillary angiomatosis and peliosis, chronic bacteraemia and endocarditis, trench fever). b. henselae is transmitted to humans by scratch or bite of a bacteraemic, but asymptomatic, cat, which ev ...19968618634
[cat scratch disease. bartonella henselae antibodies and dna detection in regional lymphadenopathy].history and clinical findings: two hard, pressure-sensitive nodules developed in the lower jaw of a 22-year-old woman. after a dental cause had been excluded, she was treated for suspected tonsillitis with ceftibuten. erythrocyte sedimentation rate was increased to 18 mm in the first hour. there were no other significant biochemical findings and fine-needle biopsy of one of the nodules showed nonspecific inflammatory reaction. investigations: sonography revealed two lymph nodes, 7 and 22 mm in d ...19968631227
isolation of bartonella henselae from domestic cats in japan.during the period from january to march 1995, the authors first isolated bartonella henselae from the blood of three (9.1%) of 33 domestic cats in japan. the three cats were a 1.5-year male pet cat-old with urinary retention, and 6-year-old female pound and age-unknown female pet cats with no abnormalities. the blood was taken in a lysis-centrifugation tube (wampole isolator tube) and cultured on 5% rabbit-blood heart infusion agar plates at 35 degrees c in the 5% co2 atmosphere. visible tiny ro ...19968645765
bartonella henselae endocarditis in an immunocompetent adult.we describe a case of aggressive bartonella henselae endocarditis in an immunocompetent man who owned a cat. aortic valve replacement was required, and his infection was diagnosed by histology, serology, and polymerase chain reaction analysis. the manifestations of his disease included mediastinal lymphadenopathy, glomerulonephritis, myocarditis, and a petechial rash; the unusual finding of a positive titer of c-antineutrophil cytoplasmic antibodies was noted. serological titers were markedly el ...19958645787
image cytometry and topographical analysis of proliferation of endothelial cells in vitro during bartonella (rochalimaea) infection.bartonella quintana and bartonella henselae are clinically associated with proliferative neovascular lesions. the effect of bartonella infection on human endothelial cells was evaluated in vitro by quantitative image analysis. particular emphasis is placed on reporting the methodologies employed. human umbilical vein endothelial cells were infected in vitro with the two bartonella species. cell proliferation (cell density), cell morphology (cell surface, form and elongation factors) and spatial ...19968844102
bartonella (rochalimaea) antibodies, dementia, and cat ownership among men infected with human immunodeficiency virus.to determine the association between recent human immunodeficiency virus (hiv)-associated dementia and serum antibodies to bartonella (rochalimaea) henselae, we performed a nested case control study within the multicenter aids cohort study in los angeles. we measured serum igg and igm antibodies to b. henselae with use of enzyme immunoassay in 369 hiv-seropositive and hiv-seronegative participants with and without recent neuropsychological deterioration. data on pet ownership were also collected ...19958645846
acquisition of the cat scratch disease agent bartonella henselae by cat fleas (siphonaptera:pulicidae).we assayed the ability of cat fleas to become infected with bartonella henselae, using an artificial feeding device. fleas fed a concentration of 1 x 10(5) cfu/ml in blood were examined using immunofluorescent antibody assay and polymerase chain reaction. bacteria were present in the gut at 3 h, and persisted up to 9 d after infection. qualitatively, the density of b. henselae was greater in the flea gut at 9 d, indicating that replication was occurring in the gut. b. henselae also was detected ...19968667399
[cat scratch disease. atypical forms].first described by robert debré in 1950, cat scratch disease, usually observed in children and young adults (80% of the case occur in subjects under 18), is the principal cause of chronic benign lymph node enlargement. the centers for disease control at atlanta currently recognize afipia felis and rochalimaea henselae as the causal agents of cat scratch disease. cats transmit the disease to humans by skin scratches or by licking open wounds. the bacilli can also be transmitted by dogs, monkeys, ...19968685112
bilateral optic disc edema and multifocal retinal lesions without loss of vision in cat scratch disease. 19968694710
bacillary angiomatosis: microbiology, histopathology, clinical presentation, diagnosis and management.bacillary angiomatosis is known to be caused by a rickettsial organism; rochalimaea henselae. this causative agent has been compared with different microorganisms and clinical conditions that appear in similar settings buy have been clearly differentiated from them; e.i. cat-scratch disease (afipia felis), bartonella bacilliformis, other rochalimaea sp., kaposi's sarcoma, lobular capillary hemangioma, angiosarcoma, and epithelioid hemangioma. clinically the bacillary angiomatosis (ba) skin lesio ...19958703269
evaluation of an extended blood culture protocol to isolate fastidious organisms from patients with aids.recent reports of fastidious pathogens suggest the need for special blood cultures for immunocompromised patients. blood cultures from 45 human immunodeficiency virus (hiv)-infected patients with unexplained fever (> or = 38.0 degrees c) and cd4 counts of < 125 cells per mm3 were collected into a vacuum tube with sodium polyanetholsulfonate, an isolator tube, and bactec aerobic and anaerobic bottles. blood from the sodium polyanethosulfonate tube was inoculated into bactec 13a bottles, which wer ...19968880497
cat-scratch disease and bartonella henselae infections in children. 19968880885
new pathogens, and diseases old and new. i) afipia felis and rochalimaea. ii) parvovirus b 19. iii) herpesvirus 6.the paper describes events that in the last fifteen years, have led to the identification of the aetiological agents of three widely known diseases: cat scratch disease, erythema infectiosum and exanthem subitum. the particular features of afipia felis and rochalimaea, parvovirus b 19 and herpesvirus 6 are presented. the paternity of new diseases (i.e. bacillary angiomatosis, bacillary peliosis hepatitis, les-like syndrome, chronic fatigue syndrome, petechial glove and sock syndrome, etc.) has a ...19958710408
bartonella (rochalimaea) infections: beyond cat scratch.five species of bartonella have been found to infect humans, henselae, quintana, elizabethae, bacilliformis, and vinsonii. the most common of these in north america are bartonella quintana and bartonella henselae, the agents of trench fever, bacillary angiomatosis, and parenchymal peliosis, and in the case of b. henselae cat-scratch disease. b. bacilliformis is endemic in peru and ecuador, where it causes oroya fever or carrion's disease. new methods of diagnosing bartonella infections have resu ...19968712787
unraveling mysteries associated with cat-scratch disease, bacillary angiomatosis, and related syndromes.the search for the infectious agents responsible for cat-scratch disease, bacillary angiomatosis, and related syndromes has a long and often circuitous history. recognition of the etiologic agents and a new understanding of the fundamental features of the epidemiology and natural history of modern day bartonella (formerly rochalimaea)-associated diseases culminate a multipartite story that combines clinical medicine, traditional microbiology, and novel technological approaches to solve a long-st ...19958903149
[detection of bartonella (rochalimaea) henselae/b. quintana by polymerase chain reaction (pcr)].bartonella (rochalimaea) henselae and/or b. quintana are the causative agents of a variety of infections such as trench fever, bacillary angiomatosis, septicemia, peliosis hepatis and endocarditis. recently, b. henselae has been identified as a major cause of cat scratch disease. diagnosis of such infections is based on clinical information, histopathology, culture and serology. however, none of these methods alone is sufficiently sensitive or specific. we have used the pcr to search for dna spe ...19968720724
bartonella (rochalimaea) henselae hepatosplenic infection occurring simultaneously in two siblings. 19968729220
[visceral localizations of cat-scratch disease in an immunocompetent patient].locoregional expression of cat scratch disease is well known, but despite advances in microbiology over the last 10 years leading to the description of two new bacteria (afipia felis, bartonella henselae) the infective agent responsible for cat scratch syndrome remains unknown. until the 80s, only one systemic disease was attributed to infection with a germ in the bartonella genus: trench fever. with the onset of the aids epidemic, new clinical syndromes caused by bartonella bacteria have been d ...19968729380
an analysis of lymph node dna for possible bacterial agents of cat-scratch disease.recent investigations have implicated afipia felis and rochalimaea henselae as possible agents of cat-scratch disease (csd). we studied lymph nodes with necrotizing granulomas characteristic of csd for a. felis and r. henselae dna so that the relationship of these organisms to lymph nodes with necrotizing granulomas of unknown etiology might be better defined. we examined formalin-fixed, paraffin-embedded lymph node biopsies with necrotizing granulomas suggestive of csd from 28 children obtained ...19958736593
prevalence of bartonella henselae bacteremia, the causative agent of cat scratch disease, in an australian cat population.in order to determine the prevalence of bartonella henselae becteremia in an australian cat population we examined blood cultures on a group of sydney cats. cats referred to the concord animal hospital for euthanasia were selected randomly for blood culture and serum sampling. blood samples were lysed and centrifuged and then cultured for up to five weeks. suspicious colonies were identified biochemically as probable b. henselae. selected isolates were confirmed as b. henselae using the polymera ...19968912359
an unusual presentation of cat scratch encephalitis.cat scratch disease is an infectious illness that has been recognized since the 1880s; however, our understanding and knowledge of it is still evolving (1). it was not until 1991 that the etiologic species, rochalimaea, was finally confirmed (2,3). only recently have the breadth of its clinical spectrum and the population at risk been appreciated. we now realize that signs and symptoms that had been considered cardinal for diagnosis may be absent. cat scratch disease was known to afflict primari ...19958747625
bartonella henselae infection in cats: evaluation during primary infection, treatment, and rechallenge infection.bartonella henselae infection was established in eight cats of various ages by experimental inoculation. all cats remained persistently bacteremic until they were treated 4 to 7 weeks after primary inoculation. antibody titers increased and peaked between 4 and 12 weeks for all cats. treatment with doxycycline for 1 week was effective in suppressing bacteremia in all cats but was effective in clearing infection from only four cats. amoxicillin, given subsequently, was effective in clearing the i ...19968784569
predominance of two bartonella henselae variants among cat-scratch disease patients in the netherlands.restriction endonuclease analysis of the pcr-amplified 16s-23s rrna gene spacer region was used to investigate the prevalence of bartonella henselae variants in samples from cat-scratch disease (csd) patients. analysis of spacer pcr fragments from 27 bartonella dna-positive samples from dutch patients with csd with alui revealed two restriction fragment length polymorphism (rflp) patterns, patterns a and b. twenty samples yielded b. henselae pattern a, and 7 samples yielded b. henselae pattern b ...19968788996
cat-scratch disease. 19968794184
mr imaging of the knee: findings in cat-scratch disease. 19968615286
experimentally induced bartonella henselae infections followed by challenge exposure and antimicrobial therapy in cats.to elucidate kinetics of bartonella henselae bacteremia and igg response, evaluate antibiotic therapy, and investigate challenge exposure in cats.19968950424
new serotype of bartonella henselae in endocarditis and cat-scratch disease.the fastidious nature of bartonella henselae is such that demonstration of clinical infection relies mainly on serological or molecular biological methods. only five isolates have been obtained from patients with cat-scratch disease (csd) and none from endocarditis.19968618486
[cat scratch disease in a 14-year-old boy]. 19968975226
[cat-scratch disease as a diagnostic problem of lymphadenopathy].the diagnosis of cat-scratch disease is based on history and clinical symptoms. we present a case of a 4-year-old girl admitted to our unit with suspicion of histiocytosis x after histologic evaluation of a submandibular lymph node biopsy. on the basis of history, clinical features and histologic reevaluation, the diagnosis of cat-scratch disease was made.19968975227
the histologic spectrum of hepatic cat scratch disease. a series of six cases with confirmed bartonella henselae infection.cat scratch disease (csd), a common cause of regional lymphadenitis, has been linked to bartonella henselae infection. although rare, dissemination with hepatic involvement has been documented. six cases of hepatic csd were retrieved and probed for b. henselae dna. hematoxylin-eosin, trichrome, methenamine silver, gram, ziehl-neelsen, and warthin-starry stained slides were reviewed by all authors, and the histologic findings were recorded. b. henselae infection was confirmed in all cases using c ...19968827032
bacillary angiomatosis of the cervix and vulva in a patient with aids.bacillary angiomatosis is a clinicopathologic entity that most often is identified in the skin of patients with aids. this report presents an example of bacillary angiomatosis of the female genital tract.19968841262
prevalence of bartonella henselae antibodies among human immunodeficiency virus-infected patients from bahrain. 19968842286
bacillary angiomatosis associated with extensive esophageal polyposis: a new mucocutaneous manifestation of acquired immunodeficiency disease (aids).bacillary angiomatosis is a rare infection that has been associated with human immunodeficiency virus infection. the causative organism is rochalimaea henselae and contact with cats is a risk factor. we present a case of a 37-yr-old man who had recent prolonged exposure to a cat and presented with fever, iron deficiency anemia, and guaiac-positive stools who had biopsy-proven bacillary angiomatosis skin lesions and on esophagogastroduodenoscopy had multiple, diffuse, friable, polypoid lesions in ...19968855753
unsuspected hepatosplenic involvement in patients hospitalized with cat-scratch disease. 19968858685
intermediate uveitis and retinal vasculitis as manifestations of cat scratch disease.to study the ocular manifestations of systemic rochalimaea infection.19968862061
cat-scratch disease and bacillary angiomatosis.cat-scratch disease (csd) was first described by debré in 1950, yet the causative bacterial agent of csd remained obscure until 1992, when bartonella (formerly rochalimaea) henselae was implicated in csd by serological and microbiological studies. b. henselae had initially been linked to bacillary angiomatosis (ba), a vascular proliferative disease most commonly associated with long-standing human immunodeficiency virus (hiv) infection or other significant immunosuppression. b. henselae has also ...19969025151
serological cross-reactions between bartonella quintana, bartonella henselae, and coxiella burnetii.the clinical manifestations of q fever and bartonelloses can be confused, especially in cases of infectious endocarditis. differential diagnosis of the diseases is important because the treatments required for q fever and bartonelloses are different. laboratory confirmation of a suspected case of either q fever or bartonelloses is most commonly made by antibody estimation with an indirect immunofluorescence assay. with an indirect immunofluorescence assay, 258 serum samples from patients with q ...19968862597
pathogenic mechanisms of bartonella henselae infections. 19968866818
portal triad involvement in cat-scratch disease. 19968888205
evaluation of serological response to bartonella henselae, bartonella quintana and afipia felis antigens in 64 patients with suspected cat-scratch disease.the serological response to bartonella henselae, b. quintana, and afipia felis was assessed by an indirect fluorescence antibody test (ifat) in 64 patients with suspected cat-scratch disease (csd) recruited from the bordeaux area in france. blood samples were collected from 57 patients with chronic lymphadenopathy who underwent lymph-node biopsy with suggestive histopathologic features of csd, and from an additional 7 patients with suspected csd who underwent surgical incision and drainage becau ...19968893399
will the real agent of cat-scratch disease please stand up?cat-scratch disease has been recognized since 1889 in association with the oculoglandular syndrome of parinaud. the epidemiologic association with cats was first made in 1931 and further substantiated throughout the years, refining the interaction predominantly to kittens. putative infectious agents have included numerous species of bacteria, chlamydiae, and viruses. the cultivation of afipia spp. in the late 1980s appeared to answer the mystery of the identity of the agent. however, even more r ...19968905096
does coinfection of bartonella henselae and fiv induce clinical disorders in cats?it was found that bartonella henselae (b. henselae) may induce clinical disorders in cats in natural conditions from a comparison of the serological status for b. henselae with the serostatus for feline immunodeficiency virus (fiv) and several clinical characteristics in 170 domestic cats. seropositivity for b. henselae was not significantly different between fiv antibody-positive and -negative cats (18.4% vs 16.0%). the incidence of clinical characteristics were compared among four cat groups d ...19968908605
serological study of bartonella henselae in cat scratch disease in japan.it has become clear that bartonella henselae is a common cause of cat scratch disease (csd). the indirect fluorescence antibody (ifa) test for detection of igg and igm antibodies to b. henselae concerning csd showed that 5 (50%) of 10 patients with csd had a serum igg antibody titer of 1:128 or more and that 2 (20%) patients had a serum igm antibody titer of 1:20 or more. one of 7 asymptomatic members of patients' families (14%) had igg antibody to b. henselae at a titer of 1:256. igm antibody t ...19968908613
re: imaging features of cat-scratch disease. 19968911215
bacillary angiomatosis: microbiology, histopathology, clinical presentation, diagnosis and management.bacillary angiomatosis is known to be caused by a rickettsial organism; rochalimaea henselae. this causative agent has been compared with different microorganisms and clinical conditions that appear in similar settings but that have been clearly differentiated from them; e.i. cat-scratch disease (afipia felis), bartonella bacilliformis, other rochalimaea sp., kaposi;s sarcoma, lobular capillary hemangioma, angiosarcoma, and epithelioid hemangioma. clinically the bacillary angiomatosis (ba) skin ...19968916440
cloning, expression and sequence analysis of the bartonella henselae gene encoding the htra stress-response protein.a cloned fragment of bartonella (rochalimaea) henselae (bh) dna was found to direct synthesis of an immunoreactive protein in escherichia coli (ec). sequence analysis revealed an open reading frame of 1509 nucleotides encoding a protein of 503 amino acids that exhibited extensive identity (over the entire protein) with the htra stress-response proteins of brucella abortus (59%), ec (37%) and salmonella typhimurium (36%). when the putative htra gene was amplified by polymerase chain reaction and ...19968921888
generalized infection with bartonella henselae following infection due to epstein-barr virus. 19968922830
[cat scratch disease. an overview for the ent physician].background: cat scratch disease (csd) is a relatively common cause of chronic lymphadenopathy in the usa. in the present paper the authors describe recent advances in the understanding of this disorder focusing on etiology, clinical aspects, diagnostic management, and therapy. etiology: rochalimaea henselae and afipia felis, two gram-negative bacteria, have recently been isolated from lymph node tissue of patients suffering from csd. the current literature reveals that rochalimaea henselae seems ...19968924168
antibodies to bartonella species in inner-city intravenous drug users in baltimore, md.bartonella quintana has recently been associated with homeless alcoholic men. both b quintana and bartonella henselae have been shown to be opportunistic pathogens of people with acquired immunodeficiency syndrome. the reservoirs and modes of transmission of these infections are incompletely known.19968944742
comparative seroreactivity to bartonella henselae and bartonella quintana among cats from israel and north carolina.bartonella henselae, the predominant cause of cat scratch disease, and bartonella quintana, the cause of trench fever, are closely related bartonella species that induce cross-reactivity when cat or human sera are tested using an indirect immunofluorescence antibody (ifa) test. cats are the natural reservoir for b. henselae, whereas a mammalian reservoir host for b. quintana has not been identified. serum samples from 114 cats from israel and 114 cats from north carolina were tested by ifa for s ...19968810011
identification of bartonella henselae and b. quintana 16s rdna sequences by branch-, genus- and species-specific amplification.given the controversy surrounding the aetiology of cat scratch disease and the association of both bartonella henselae and b. quintana with bacillary angiomatosis, a method for the direct detection in clinical samples of 16s rrna from the proteobacteria alpha subgroup was developed. the primary structure of amplified 16s rdna was determined by cloning and sequencing. three sequences were identified: one corresponded exactly to genbank accession number m73229 (b. henselae); the second was related ...19968810946
experimental transmission of bartonella henselae by the cat flea.bartonella henselae is an emerging bacterial pathogen, causing cat scratch disease and bacillary angiomatosis. cats bacteremic with b. henselae constitute a large reservoir from which humans become infected. prevention of human infection depends on elucidation of the natural history and means of feline infection. we studied 47 cattery cats in a private home for 12 months to determine the longitudinal prevalence of b. henselae bacteremia, the prevalence of b. henselae in the fleas infesting these ...19968818889
bartonella henselae infection mimicking systemic onset juvenile chronic arthritis in a 2 1/2-year-old girl. 19968823702
cat scratch disease: detection of bartonella henselae dna in archival biopsies from patients with clinically, serologically, and histologically defined disease.serological and epidemiological studies suggest that bartonella henselae is the etiological agent of cat scratch disease. we designed a study to detect b. henselae in archival biopsies by polymerase chain reaction amplification of the 16s rrna gene followed by southern blot hybridization. forty-two histologically defined cat scratch disease biopsies and eighteen controls were selected for blinded analysis. after testing, charts were reviewed for clinical, immunological, and microbial evidence of ...19968952548
parinaud's oculoglandular conjunctivitis and cat-scratch disease. 19968989598
maintenance of broad-host-range incompatibility group p and group q plasmids and transposition of tn5 in bartonella henselae following conjugal plasmid transfer from escherichia coli.the first demonstration of conjugal plasmid transfer from escherichia coli to bartonella henselae is reported. transconjugants bearing plasmids of incompatibility groups p (incp) and q (incq), expressing various resistance markers, were generated. tn5 transposons delivered on suicide plasmids by conjugation showed transpositional insertion into random chromosomal sites.19978990308
diagnostic value of the indirect immunofluorescence assay in cat scratch disease with bartonella henselae and afipia felis antigens.serum samples from 35 cat scratch disease (csd) patients, 180 control patients (123 without lymph node enlargement and 57 with lymph node enlargement not evoking csd), and 102 nonpatient subjects (35 with cat contact and 67 without cat contact) were tested by semiquantitative indirect immunofluorescence assay for the presence of antibodies directed to afipia felis (atcc 53690t) or bartonella henselae (atcc 49882t). the csd group had statistically higher antibody titers against b. henselae than t ...19968991636
experimental and natural infection with bartonella henselae in domestic cats.domestic cats were experimentally infected with culture propagated bartonella henselae by intradermal (i.d.) and intravenous (i.v.) routes. cats were more efficiently infected by the i.d. (8/8 cats) than by the i.v. (2/16) route. bacteremia was detected 1-3 weeks following inoculation and lasted for most cats for 1-8 months. however, one naturally infected cat was observed for 24 months and was found to be cyclically bacteremic, with bacterial levels varying one hundred fold or more from one per ...19979023040
the etest for antimicrobial susceptibility testing of bartonella henselae.the in-vitro susceptibility of 10 isolates of bartonella henselae was assessed using the etest. the organisms, one reference human strain and nine feline isolates, were grown on chocolate agar and the etests read at days 5, 8 and 11. six antibiotics, erythromycin, azithromycin, doxycycline, ciprofloxacin, rifampicin and vancomycin were evaluated. the results correlated well with published results using agar dilution. the results confirmed the high in-vitro susceptibility of b. henselae to erythr ...19969023643
isolation of bartonella (rochalimaea) henselae: effects of methods of blood collection and handling.bartonella (rochalimaea) henselae causes cat-scratch disease, bacillary angiomatosis, peliosis hepatis, and fever in humans. b. henselae can be difficult to culture axenically, and as many as 5 weeks may be required before colonies are visible. we compared how different methods of blood collection and handling affect isolation of this pathogen. blood specimens from b. henselae-infected cats were collected in both edta and isolator blood-lysis tubes and were subsequently plated onto rabbit blood- ...19979041385
detection and identification of two bartonella henselae variants in domestic cats in germany.to determine the prevalence of bacteremia caused by bartonella henselae in domestic cats in the region of freiburg, germany, we investigated culture of blood from 100 cats from 89 different households over a 12-month period. b. henselae could be isolated from 13% (13 of 100) of these cats. in eight households with two cats each and in one household with three cats, b. henselae bacteremia was found either in all of the animals or in none of the animals. positive cultures were more likely to be fo ...19979041393
the expanding spectrum of bartonella infections: ii. cat-scratch disease.recent advancements and developments in molecular biotechnology have allowed more precise reclassification of many microorganisms. with the use of these new taxonomy tools, several organisms previously thought to belong to other genera have been recently described as bartonellae. of the 11 organisms now described as bartonella spp., only four have been shown to be pathogenic for humans. table 1 lists the four bartonella human pathogens along with the their known epidemiology and the scope and ra ...19979041596
in vitro susceptibilities of bartonella henselae, b. quintana, b. elizabethae, rickettsia rickettsii, r. conorii, r. akari, and r. prowazekii to macrolide antibiotics as determined by immunofluorescent-antibody analysis of infected vero cell monolayers.the in vitro susceptibilities of bartonella (rochalimaea) henselae, b. quintana, b. elizabethae, rickettsia akari, r. conorii, r. prowazekii, and r. rickettsii to different concentrations of azithromycin, clarithromycin, dirithromycin, erythromycin, and roxithromycin in vero cell cultures were evaluated. bartonella and rickettsia spp. were allowed to initiate infection of the antibiotic-free vero cell monolayers, which were maintained in 16-chamber microscope slides in the absence of antibiotics ...19979055996
survey of veterinary professionals and other veterinary conference attendees for antibodies to bartonella henselae and b quintana.to determine serologic and epidemiologic characteristics of an occupational group potentially at risk for bartonella sp infection.19979057914
acute multifocal retinitis.to describe the clinical presentation, ophthalmoscopic and fluorescein angiographic findings, and natural history of 14 eyes in nine otherwise healthy, young-to-middle-age adults with idiopathic, acute, multifocal retinitis.19979063244
hepatosplenic cat-scratch disease and abdominal pain.there have been several recent reports that cat-scratch disease (csd) causes a multiplicity of atypical clinical syndromes. we recently diagnosed hepatosplenic csd in a child who was seen with fever and abdominal pain. we report this case and 10 other patients with hepatosplenic csd and highlight the importance of abdominal pain in this clinical entity.19979076813
[cat-scratch disease. a report of 4 cases and a review of the literature].four cases of cat-scratch diseases are here reported and a review of the literature is made. the disease, apart from its typical presentation form as a usually self-limited regional lymph node enlargement, can occasionally spread and involve several organs systems. indirect immunofluorescence serological tests have been of help for its diagnosis and should be included among the diagnostic criteria for the disease. in particular cases, nuclear magnetic resonance can be useful to suggests the diag ...19979102668
cat-scratch disease and related clinical syndromes.bartonella (rochalimaea) henselae is a common cause of cat-scratch disease. this newly identified bacterium is also the cause of several other clinical syndromes, including bacillary angiomatosis, bacillary peliosis hepatitis and splenitis, and acute and relapsing bacteremia. a high percentage of young cats carry b. henselae. fortunately, serious complications of b. henselae infections are rare in immunocompetent patients. cat-scratch disease is usually a self-limited illness that does not neces ...19979105205
pathogenetic role of phagocytic abnormalities in human virus immunodeficiency infection: possible therapeutical approaches. a review.polymorphonuclear cells (pmn) and monocytes/macrophages (m/m) represent the first defence line against invading microorganisms. both phagocytic cell functions are precociously compromised in human immunodeficiency virus (hiv)-infected subjects, thus leading to infectious and neurological complications in the late stages of disease. among intracellular pathogens, emerging bacteria such as bartonella henselae and rhodococcus equi can cause peculiar clinical pictures, i.e. the bacillary parenchimal ...19979130002
coinfection with bartonella clarridgeiae and bartonella henselae and with different bartonella henselae strains in domestic cats.bartonella clarridgeiae and several strains of bartonella henselae, the agent of cat scratch disease, with variations in the 16s rrna gene have been found to infect the blood of cats. an epidemiologic study of bartonella infection in domestic french cats revealed that of 436 cats sampled, 5 cats (1.1%) were coinfected with b. henselae and b. clarridgeiae and 2 cats (0.5%) were coinfected with two strains of b. henselae with variations in the 16s rrna gene, b. henselae type i and type ii. in an i ...19979230394
Displaying items 101 - 200 of 1673