Publications
Title | Abstract | Year(sorted ascending) Filter | PMID Filter |
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surveys on seroprevalence of canine monocytic ehrlichiosis among dogs living in the ivory coast and gabon and evaluation of a quick commercial test kit dot-elisa. | canine monocytic ehlichiosis (cme), an enzootic disease in africa, has been studied in canine blood samples (serum). these dogs, without any clinical sign of disease, were living in abidjan (ivory coast) and in several small villages located in northeasst gabon (ogooué ivindo). the results obtained by indirect fluorescent antibody (ifa) test, used as a point of reference, and by a quick test dot-elisa were compared. blood samples taken from 390 asymptomatic dogs in 2003 (137 in ivory coast and 2 ... | 2006 | 17114755 |
an investigation into the distribution, host-preference and population density of ixodid ticks affecting domestic animals in bangladesh. | to study the distribution, host-preference and population density of ixodid ticks in bangladesh, an attempt was made to collect adult ticks from various host animals in three distinct topographic zones, viz. flood plains, hills and steppe 'barind'. five species of ixodid ticks were recorded, namely, boophilus microplus (56.3%), haemaphysalis bispinosa (11.3%), rhipicephalus sanguineus (14.7%), hyalomma anatolicum anatolicum (15.0%) and amblyomma testudinarium (2.8%). the data showed that b. micr ... | 2006 | 17243476 |
developmental profiles in tick water balance with a focus on the new rocky mountain spotted fever vector, rhipicephalus sanguineus. | recent reports indicate that the common brown dog tick, or kennel tick, rhipicephalus sanguineus (latreille) (acari: ixodidae) is a competent vector of rocky mountain spotted fever in the u.s.a. this tick is of concern to public health because of its high frequency of contact, as it has a unique ability to thrive within human homes. to assess the moisture requirements necessary for survival, water balance characteristics were determined for each developmental stage, from egg to adult. this is th ... | 2006 | 17199747 |
epidemiology of rickettsioses in north africa. | the first description of mediterranean spotted fever (msf) was made by conor and brush in 1910 in tunisia, where, at the same time, nicolle described the role of lice in transmission of epidemic typhus. however, along this century, there have been few and fragmentary reports about ecology and epidemiology of rickettsioses in north africa. this region was always considered, for these diseases, like other mediterranean regions. the most human tick-borne rickettsiosis known to occur in north africa ... | 2006 | 17114678 |
rickettsial agents in egyptian ticks collected from domestic animals. | to assess the presence of rickettsial pathogens in ticks from egypt, we collected ticks from domestic and peridomestic animals between june 2002 and july 2003. dna extracts from 1019 ticks were tested, using pcr and sequencing, for anaplasma spp., bartonella spp., coxiella burnetii, ehrlichia spp., and rickettsia spp. ticks included: 29 argas persicus, 10 hyalomma anatolicum anatolicum, 55 hyalomma anatolicum excavatum, 174 hyalomma dromedarii, 2 hyalomma impeltatum, 3 hyalomma marginatum rufipe ... | 2006 | 17004028 |
babesia spp. identified by pcr in ticks collected from domestic and wild ruminants in southern switzerland. | concurrent infections with vector-borne pathogens affected a cattle herd in switzerland, and one of the pathogens was identified as babesia bigemina, which had never been observed in this country before. therefore, a survey of the occurrence of ruminant babesia spp. and their tick vectors in switzerland was conducted. a total of 2,017 ticks were collected from sheep, goats, cattle, and wild ruminants (deer, roe deer, and chamois) in southern parts of switzerland and identified morphologically. t ... | 2006 | 17021198 |
molecular characterization of anaplasma platys strains from dogs in sicily, italy. | the genetic diversity of anaplasma platys (rickettsiales: anaplasmataceae) strains is currently poorly defined. the present study was designed to characterize a. patys strains in dogs from palermo, sicily, italy, using a combination of pcr and sequence analysis of the 16s rdna, heat shock operon groesl and citrate synthase (glta) genes. | 2006 | 16872489 |
evaluation of an imidacloprid (8.8% w/w)--permethrin (44.0% w/w) topical spot-on and a fipronil (9.8% w/w)--(s)-methoprene (8.8% w/w) topical spot-on to repel, prevent attachment, and kill adult rhipicephalus sanguineus and dermacentor variabilis ticks on dogs. | this study evaluated the effectiveness of two topical spot-on formulations, imidacloprid (8.8% w/w)--permethrin (44.0% w/w) and fipronil (9.8% w/w)--(s)-methoprene (8.8% w/w), to repel, prevent the attachment of, and kill adult rhipicephalus sanguineus and dermacentor variabilis on dogs. twelve purpose-bred beagles were distributed into three groups of four dogs each; one group served as untreated controls and each of the other two groups received one of the test products. dogs were exposed to 2 ... | 2006 | 17039441 |
[characterization of rickettsia spp. circulating in a silent peri-urban focus for brazilian spotted fever in caratinga, minas gerais, brazil]. | the present study was intended to characterize rickettsia spp. circulating in arthropod vectors in caratinga, minas gerais, brazil, by pcr and to investigate the presence of antibodies against the spotted fever rickettsiae group (sfrg) in dogs and horses. 2,610 arthropods were collected and taxonomically identified. dna samples obtained from these vectors were submitted to pcr and cycle-sequenced. ctenocephalides and amblyomma cajennense showed sequences presenting 100.0% homology with r. felis. ... | 2006 | 16583093 |
canine babesiosis in france. | canine babesiosis has a high prevalence in france and continues to constitute a diagnostic challenge. this paper presents essential data derived from epidemiological surveys in order to define the main features of this disease. atypical forms are frequent, the diagnosis must be confirmed by blood smears and treatment is based on the use of imidocarb. prophylaxis currently remains insufficient. | 2006 | 16507334 |
prevalence, risk factor analysis, and follow-up of infections caused by three feline hemoplasma species in cats in switzerland. | recently, a third novel feline hemotropic mycoplasma sp. (aka hemoplasma), "candidatus mycoplasma turicensis," in a cat with hemolytic anemia has been described. this is the first study to investigate the prevalence, clinical manifestations, and risk factors for all three feline hemoplasma infections in a sample of 713 healthy and ill swiss cats using newly designed quantitative real-time pcr assays. "candidatus mycoplasma haemominutum" infection was detected in 7.0% and 8.7% and mycoplasma haem ... | 2006 | 16517884 |
infection of human endothelial cells with spotted fever group rickettsiae stimulates cyclooxygenase 2 expression and release of vasoactive prostaglandins. | rickettsiae, a diverse group of obligately intracellular gram-negative bacteria, include etiologic agents of the spotted fever and typhus groups of diseases. rocky mountain spotted fever and boutonneuse fever, due to rickettsia rickettsii and r. conorii, respectively, are characterized by widespread infection of the vascular endothelium, microvascular injury, and vasculitis. cultured human endothelial cells (ec) are highly susceptible to infection and respond by altering the expression of adhesi ... | 2006 | 16926398 |
ticks, ivermectin, and experimental chagas disease. | following an infestation of dogticks in kennels housing dogs used for long-term studies of the pathogenesis of chagas disease, we examined the effect of ivermectin treatment on the dogs, ticks, trypanosome parasites, and also on triatomine vectors of chagas disease. ivermectin treatment was highly effective in eliminating the ticks, but showed no apparent effect on the dogs nor on their trypanosome infection. triatominae fed on the dogs soon after ivermectin treatment showed high mortality, but ... | 2006 | 16444412 |
novel acetylcholinesterase target site for malaria mosquito control. | current anticholinesterase pesticides were developed during world war ii and are toxic to mammals because they target a catalytic serine residue of acetylcholinesterases (aches) in insects and in mammals. a sequence analysis of aches from 73 species and a three-dimensional model of a malaria-carrying mosquito (anopheles gambiae) ache (agache) reported here show that c286 and r339 of agache are conserved at the opening of the active site of aches in 17 invertebrate and four insect species, respec ... | 2006 | 17183688 |
national assessment of human health effects of climate change in portugal: approach and key findings. | in this study we investigated the potential impact of climate change in portugal on heat-related mortality, air pollution-related health effects, and selected vectorborne diseases. the assessment used climate scenarios from two regional climate models for a range of future time periods. the annual heat-related death rates in lisbon may increase from between 5.4 and 6 per 100,000 in 1980-1998 to between 8.5 and 12.1 by the 2020s and to a maximum of 29.5 by the 2050s, if no adaptations occur. the ... | 2006 | 17185290 |
serologic evidence for exposure to rickettsia rickettsii in eastern arizona and recent emergence of rocky mountain spotted fever in this region. | during 2002 through 2004, 15 patients with rocky mountain spotted fever (rmsf) were identified in a rural community in arizona where the disease had not been previously reported. the outbreak was associated with rickettsia rickettsii in an unexpected tick vector, the brown dog tick (rhipicephalus sanguineus), which had not been previously associated with rmsf transmission in the united states. we investigated the extent of exposure to r. rickettsii in the local area through serologic evaluations ... | 2006 | 17187578 |
boutonneuse fever and climate variability. | researchers have long appreciated the role of climate in vector-borne diseases, including the resurgence of boutonneuse fever (bf). portugal usually is classified as having temperate mediterranean climate. in this new century, in analyzing the data from the meteorology institute, this pattern has changed and an accentuated variability in climate is being observed. bf (febre escaro nodular) is endemic and high season is from late spring and summer. the brown dog tick rhipicephalus sanguineus. is ... | 2006 | 17114701 |
prevalence of spotted fever group rickettsia species detected in ticks in la rioja, spain. | our objective was to learn the prevalence of spotted fever group (sfg) rickettsia detected in ticks in la rioja, in the north of spain. from 2001 to 2005, 496 ticks representing 7 tick species were analysed at the hospital de la rioja. ticks were removed from humans with or without rickettsial syndrome (n = 59) or collected from mammals (n = 371) or from vegetation by dragging (n = 66). the presence of sfg rickettsia in these ticks was investigated by semi-nested pcr (ompa gene) and sequencing. ... | 2006 | 17114730 |
spotted fever group rickettsiae in ticks feeding on humans in northwestern spain: is rickettsia conorii vanishing? | during a 7-year study, we identified and analyzed by pcr 4,049 ticks removed from 3,685 asymptomatic patients in castilla y león (northwestern spain). a total of 320 ticks (belonging to 10 species) were pcr-positive for rickettsiae. comparison of amplicon sequences in databases enabled us to identify eight different spotted fever group (sfg) rickettsiae: rickettsia slovaca, rickettsia sp. irs3/irs4, r. massiliae/bar29, r. aeschlimannii, rickettsia sp. rpa4/dns14, r. helvetica, rickettsia sp. dms ... | 2006 | 17114733 |
rocky mountain spotted fever in arizona: documentation of heavy environmental infestations of rhipicephalus sanguineus at an endemic site. | a recent epidemiologic investigation identified 16 cases and 2 deaths from rocky mountain spotted fever (rmsf) in two eastern arizona communities. prevalence studies were conducted by collecting free-living ticks (acari: ixodidae) from the home sites of rmsf patients and from other home sites within the community. dry ice traps and flagging confirmed heavy infestations at many of the home sites. only rhipicephalus sanguineus ticks were identified and all developmental stages were detected. it is ... | 2006 | 17114735 |
an outbreak of rocky mountain spotted fever associated with a novel tick vector, rhipicephalus sanguineus, in arizona, 2004: preliminary report. | this study describes preliminary results of an investigation of rmsf in arizona associated with the brown dog tick, rhipicephalus sanguineus. high numbers of dogs and heavy infestations of ticks created a situation leading to human disease. | 2006 | 17114736 |
first molecular detection of r. conorii, r. aeschlimannii, and r. massiliae in ticks from algeria. | ticks collected in northern algeria between may 2001 and november 2003 were tested by pcr for the presence of rickettsia spp. dna using primer amplifying glta and ompa genes. three different spotted fever group rickettsias were amplified from these ticks: r. conorii subsp. p. conorii strain malish in rhipicephalus sanguineus, r. aeschlimannii in hyalomma marginatum, and r. massiliae in rhipicephalus turanicus. our results confirm the presence of r. conorii in ticks in algeria and provide the fir ... | 2006 | 17114743 |
an unexpected inhibitory activity of kunitz-type serine proteinase inhibitor derived from boophilus microplus trypsin inhibitor on cathepsin l. | several bpti-kunitz-type serine proteinase inhibitors were described in tick boophilus microplus and rhipicephalus sanguineus species. in this work, we present a synthetic gene based on two tick bpti-kunitz-type serine proteinase inhibitors, the first domain of b. microplus trypsin inhibitor-a (bmti-a) and the carrapatin, the inhibitors were named bmtisint and bmtisint mut. our present results showed that bmtisint and bmtisint mut inhibited trypsin (k(i) 3.3 and 1.0 nm) and human plasma kallikre ... | 2006 | 16414023 |
spotted fever group rickettsial infection in dogs from eastern arizona: how long has it been there? | a serosurvey of free-roaming dogs for antibodies to spotted fever group rickettsiae was conducted using archival samples that had been collected in the white mountain region of eastern arizona during a plague study in 1996. immunoglobulin g antibodies to rickettsia rickettsii (5.1%) and to r. rhipicephali (3.6%) were demonstrated, and no cross-reactive samples were identified. this study indicates that r. rickettsii was likely present in the dog populations in this area prior to the recognition ... | 2006 | 17114769 |
molecular typing of novel rickettsia rickettsii isolates from arizona. | seven isolates of rickettsia rickettsii were obtained from a skin biopsy, two whole-blood specimens, and from rhipicephalus sanguineus ticks from eastern arizona. molecular typing of seven isolates of r. rickettsii and dna samples from two other rh. sanguineus ticks infected with r. rickettsii was conducted by pcr and dna sequencing of rompa and 12 variable-number tandem repeat regions (vntrs). all dna specimens from arizona were identical to each other and to reference human and dermacentor and ... | 2006 | 17114781 |
[evaluation of ectoparasites and hemoparasites in dogs kept in apartments and houses with yards in the city of juiz de fora, minas gerais, brazil]. | fleas and ticks transmit various pathogens while feeding on the blood of dogs. this study sought to verify the occurrence of ectoparasitism and hemoparasitism in dogs from two urban areas in the city of juiz de fora, minas gerais, brazil. between february and august 2003, 101 dogs were studied: 50 came from apartments in the downtown region and 51 from houses with grassy yards. the ectoparasites were collected and conserved in etanol 70%. the occurrence of hemoparasites was verified by examining ... | 2006 | 16646996 |
molecular method for identification of rickettsia species in clinical and environmental samples. | we present a pcr method targeting the 23s-5s internal transcribed spacer coupled with reverse line blotting that allows rickettsia species detection and identification in a single step. the method is highly sensitive and specific in identifying rickettsia species from both patient and environmental samples. the generic approach used allowed us to identify new pathogens. | 2006 | 17035495 |
phylogenetic analysis of "candidatus mycoplasma turicensis" isolates from pet cats in the united kingdom, australia, and south africa, with analysis of risk factors for infection. | two hemotropic mycoplasmas have been recognized in cats, mycoplasma haemofelis and "candidatus mycoplasma haemominutum." we recently described a third feline hemoplasma species, designated "candidatus mycoplasma turicensis," in a swiss cat with hemolytic anemia. this isolate induced anemia after experimental transmission to two specific-pathogen-free cats and analysis of the 16s rrna gene revealed its close relationship to rodent hemotropic mycoplasmas. the agent was recently shown to be prevale ... | 2006 | 17035497 |
rickettsia africae in the west indies. | rickettsia africae is the agent of african tick-bite fever, a mild but common disease of local persons and tourists in africa. the major vector of this spotted fever group rickettsia is most likely amblyomma variegatum, the tropical bont tick, which has become widely distributed through the west indies in the last 30 years. this report reviews all available information on r. africae in the west indies. | 2006 | 16494746 |
dog tick-borne diseases in sicily. | in sicily many tick borne diseases are endemic, in particular way those that see like main carrier ticks that prefer, for their vital cycle, climatic conditions characterized by high temperatures and a warmth-humid atmosphere. the more important pathologies transmitted by ticks causing diseases in dogs are babesiosis and ehrlichiosis. borrelia burgdorferi, anaplasma phagocytophilum, rickettsia conorii, coxiella burnetii and tick transmitted encephalitis virus assume particular relevance because ... | 2006 | 16881419 |
the environmental-endocrine basis of gynandromorphism (intersex) in a crustacean. | commensurate with the decline in many crustacean populations has been an accumulation in reports of sexually ambiguous individuals within these populations. the cause of gynandromorphism or intersex among crustaceans is unknown. we show that gynandromorphism in the branchiopod crustacean daphnia magna is initiated by the sex-determining hormone methyl farnesoate when levels of the hormone are intermediate between low levels that stimulate the production of broods containing all female offspring ... | 2006 | 17205107 |
the complete mitochondrial genome of the sea spider nymphon gracile (arthropoda: pycnogonida). | mitochondrial genomes form units of genetic information replicating indepentently from nuclear genomes. sequence data (most often from protein-coding genes) and other features (gene order, rna secondary structure) of mitochondrial genomes are often used in phylogenetic studies of metazoan animals from population to phylum level. pycnogonids are primarily marine arthropods, often considered closely related to chelicerates (spiders, scorpions and allies). however, due to their aberrant morphology ... | 2006 | 17087824 |
a case of histologically diagnosed tick infestation on the scalp of a korean child. | a scalp mass surgically excised from a 4-year-old korean boy was identified as a tick through histological observations. in sections of the mass, characteristic features of a tick, including its gross contour, cuticular structures, well developed musculature and salivary glands, and the capitulum, were discovered. in particular, the capitulum is anteriorly protruded, which strongly suggests that the specimen be a hard tick of family ixodidae. however, the present histological features were not e ... | 2006 | 16809965 |
outbreak of canine monocytic ehrlichiosis in saudi arabia. | canine monocytic ehrlichiosis (cme) is a widespread tickborne infection of canids caused by ehrlichia canis, a gram-negative obligatory intracellular bacteria belonging to the family anaplasmataceae. cme is reported to have worldwide distribution, but its presence in a region requires the presence of the vector, the brown dog tick rhipicephalus sanguineus. | 2007 | 18041697 |
[influence of aggregation on the molting process of rhipicephalus sanguineus, (latreille, 1806) (acari: ixodidae) under laboratory conditions]. | the objective of this experiment was to evaluate the influence of different aggregations on the molting process of rhipicephalus sanguineus (latreille, 1806). tick-naïve domestic rabbits (oryctolagus cuniculus) were used as experimental hosts for the parasitic phase. a total of 10 rabbits were used on the experiment. all tick free-living phases were kept in incubator at 27+/-1 degrees c, 80+/-5% relative humidity and scotophase. the periods of pre-molt, molt, percentage of ecdisis and molt rhyth ... | 2007 | 18373896 |
the complete mitochondrial genome of pseudocellus pearsei (chelicerata: ricinulei) and a comparison of mitochondrial gene rearrangements in arachnida. | mitochondrial genomes are widely utilized for phylogenetic and population genetic analyses among animals. in addition to sequence data the mitochondrial gene order and rna secondary structure data are used in phylogenetic analyses. arachnid phylogeny is still highly debated and there is a lack of sufficient sequence data for many taxa. ricinulei (hooded tickspiders) are a morphologically distinct clade of arachnids with uncertain phylogenetic affinities. | 2007 | 17961221 |
the complete mitochondrial genome of the sea spider achelia bituberculata (pycnogonida, ammotheidae): arthropod ground pattern of gene arrangement. | the phylogenetic position of pycnogonids is a long-standing and controversial issue in arthropod phylogeny. this controversy has recently been rekindled by differences in the conclusions based on neuroanatomical data concerning the chelifore and the patterns of hox expression. the mitochondrial genome of a sea spider, nymphon gracile (pycnogonida, nymphonidae), was recently reported in an attempt to address this issue. however, n. gracile appears to be a long-branch taxon on the phylogenetic tre ... | 2007 | 17908292 |
differential clearance and immune responses to tick cell-derived versus macrophage culture-derived ehrlichia chaffeensis in mice. | human monocytic ehrlichiosis is caused by a tick-transmitted rickettsia, ehrlichia chaffeensis. we recently reported that e. chaffeensis grown in tick cells expresses different proteins than bacteria grown in macrophages. therefore, we tested the hypothesis that immune responses against e. chaffeensis would be different if the mice are challenged with bacteria grown in macrophages or tick cells. we assessed the e. chaffeensis clearance from the peritoneum, spleen, and liver by c57bl/6j mice usin ... | 2007 | 17060466 |
infection of ixodes scapularis ticks with rickettsia monacensis expressing green fluorescent protein: a model system. | ticks (acari: ixodidae) are ubiquitous hosts of rickettsiae (rickettsiaceae: rickettsia), obligate intracellular bacteria that occur as a continuum from nonpathogenic arthropod endosymbionts to virulent pathogens of both arthropod vectors and vertebrates. visualization of rickettsiae in hosts has traditionally been limited to techniques utilizing fixed tissues. we report epifluorescence microscopy observations of unfixed tick tissues infected with a spotted fever group endosymbiont, rickettsia m ... | 2007 | 17125789 |
gene silencing of the tick protective antigens, bm86, bm91 and subolesin, in the one-host tick boophilus microplus by rna interference. | the use of rna interference (rnai) to assess gene function has been demonstrated in several three-host tick species but adaptation of rnai to the one-host tick, boophilus microplus, has not been reported. we evaluated the application of rnai in b. microplus and the effect of gene silencing on three tick-protective antigens: bm86, bm91 and subolesin. gene-specific double-stranded (dsrna) was injected into two tick stages, freshly molted unfed and engorged females, and specific gene silencing was ... | 2007 | 17196597 |
species diversity and seasonality of free-living ticks (acari: ixodidae) in the natural habitat of wild marsh deer (blastocerus dichotomus) in southeastern brazil. | this study evaluated the presence and seasonal activity of free-living ticks in remaining marsh areas by the paraná river, in brazil. eight field trips (once per season) for collection of ticks were performed during 2 years. using co2 traps, dragging, and visual inspection of vegetation, five free-living tick species were collected, in the following order of abundance: amblyomma cajennense, amblyomma dubitatum, amblyomma triste, amblyomma coelebs, and amblyomma nodosum. the seasonal pattern of a ... | 2007 | 16962241 |
highly prevalent coxiella sp. bacterium in the tick vector amblyomma americanum. | laboratory-reared and field-collected amblyomma americanum ticks were hosts of a coxiella sp. and a rickettsia sp. while the coxiella sp. was detected in 50 of 50 field-collected ticks, the rickettsia sp. was absent from 32% of ticks. the coxiella sp. showed evidence of a reduced genome and may be an obligate endosymbiont. | 2007 | 17085709 |
hyalomma aegyptium as dominant tick in tortoises of the genus testudo in balkan countries, with notes on its host preferences. | collection of 1327 ticks sampled throughout greece, bulgaria, romania and croatia, from 211 tortoises belonging to three species, testudo marginata schoepff, t. graeca linnaeus, and t. hermanni gmelin, revealed the presence of four species of ixodid ticks, namely hyalomma aegyptium (linnaeus), haemaphysalis sulcata canestrini and fanzago, h. inermis birula and rhipicephalus sanguineus (latreille). study confirmed the strong dominance of all life stages of h. aegyptium among ticks parasitizing we ... | 2007 | 17237970 |
rickettsia infection in five areas of the state of são paulo, brazil. | this study investigated rickettsial infection in animals, humans, ticks, and fleas collected in five areas of the state of são paulo. eight flea species (adoratopsylla antiquorum antiquorum, ctenocephalides felis felis, polygenis atopus, polygenis rimatus, polygenis roberti roberti, polygenis tripus, rhopalopsyllus lugubris, and rhopalopsyllus lutzi lutzi), and five tick species (amblyomma aureolatum, amblyomma cajennense, amblyomma dubitatum, ixodes loricatus, and rhipicephalus sanguineus) were ... | 2007 | 18094887 |
prevalence of ixodid ticks on cattle in mazandaran province, iran. | a survey was carried out to investigate the prevalence of hard tick species (acari: ixodidae) on cattle in mazandaran province, iran. a total of 953 ticks were collected from 86 infested cattle during activating seasons of ticks during 2004-2005. nine species were identified: boophilus annulatus (51.3%), rhipicephalus bursa (16.8%), haemaphysalis punctata (6.3%), ixodes ricinus (6.8%), hyalomma marginatum (12.5%), hyalomma anatolicum excavatum (5.2%), hyalomma asiaticum (0.6%), hyalomma detritum ... | 2007 | 18165714 |
sero-prevalence and risk indicators for canine ehrlichiosis in three rural areas of brazil. | ehrlichia canis has a worldwide geographic distribution, occurring particularly in tropical and subtropical areas. in brazil, the main vector in urban areas is believed to be the brown dog tick rhipicephalus sanguineus, but little is known about the occurrence, transmission and other epidemiological aspects of canine ehrlichiosis in rural areas, where amblyomma ticks are found more frequently than r. sanguineus. a sero-prevalence study of canine ehrlichiosis was carried out in three distinct rur ... | 2007 | 17204439 |
rocky mountain spotted fever, colombia. | we investigated 2 fatal cases of rocky mountain spotted fever that occurred in 2003 and 2004 near the same locality in colombia where the disease was first reported in the 1930s. a retrospective serosurvey of febrile patients showed that > 21% of the serum samples had antibodies aaainst spotted fever group rickettsiae. | 2007 | 18214179 |
life cycle of hepatozoon canis (apicomplexa: adeleorina: hepatozoidae) in the tick rhipicephalus sanguineus and domestic dog (canis familiaris). | the life cycle of the apicomplexan protozoon hepatozoon canis in its natural hosts rhipicephalus sanguineus (tick) and canis familiaris (domestic dog) was studied in an experimental infection. tick nymphs were fed on a naturally infected dog, or they were infected by percutaneous injection of blood. dogs were inoculated by ingestion of adult ticks containing mature oocysts. gamonts were in syzygy 24 hr after percutaneous injection of ticks. early oocysts were detected 96 hr after nymph repletion ... | 2007 | 17539411 |
anaplasma platys in dogs, chile. | we conducted a 16s rrna nested pcr for the genus ehrlichia and ehrlichia spp. with blood samples from 30 ill dogs in chile. phylogenetic analysis was performed by using groesl gene amplification. we identified anaplasma platys as 1 of the etiologic agents of canine ehrlichiosis. | 2007 | 18252119 |
rickettsia monacensis and human disease, spain. | we identified rickettsia monacensis as a cause of acute tickborne rickettsiosis in 2 humans. its pathogenic role was assessed by culture and detection of the organism in patients' blood samples. this finding increases the number of recognized human rickettsial pathogens and expands the known geographic distribution of mediterranean spotted fever-like cases. | 2007 | 18252123 |
isolation of rickettsia rhipicephali and rickettsia bellii from haemaphysalis juxtakochi ticks in the state of são paulo, brazil. | in the present study, attempts to isolate rickettsia in cell culture were performed individually in seven specimens of haemaphysalis juxtakochi ticks collected in the state of são paulo (southeastern brazil). rickettsia was successfully isolated by the shell vial technique and established in vero cell culture from six ticks (six isolates). dna extracted from infected cells of these isolates was tested by pcr and dna sequencing, using genus-specific rickettsia primers targeting the genes glta, ht ... | 2007 | 17142361 |
molecular cloning and characterization of a highly selective chemokine-binding protein from the tick rhipicephalus sanguineus. | ticks are blood-feeding parasites that secrete a number of immuno-modulatory factors to evade the host immune response. saliva isolated from different species of ticks has recently been shown to contain chemokine neutralizing activity. to characterize this activity, we constructed a cdna library from the salivary glands of the common brown dog tick, rhipicephalus sanguineus. pools of cdna clones from the library were transfected into hek293 cells, and the conditioned media from the transfected c ... | 2007 | 17640866 |
hepatozoon canis infection in slovakia: imported or autochthonous? | tissue samples from nine red foxes (four samples of striated muscle tissue and five samples of heart tissue) that originated from the michalovce district (slovakia), an area with endemic occurrence of canine babesiosis were examined by pcr method using primers amplifying a fragment of the 18s rrna spanning the v4 region of babesia and theileria. an unexpected determination of 450 bp dna fragment of hepatozoon canis was found in four samples. partial sequences of the 18s rrna gene from the h. can ... | 2007 | 17627439 |
identification of rickettsial isolates at the species level using multi-spacer typing. | in order to estimate whether multi-spacer typing (mst), based on the sequencing of variable intergenic spacers, could serve for the identification of rickettsia at the species level, we applied it to 108 rickettsial isolates or arthropod amplicons that include representatives of 23 valid rickettsia species. | 2007 | 17662158 |
detection of "rickettsia sp. strain uilenbergi" and "rickettsia sp. strain davousti" in amblyomma tholloni ticks from elephants in africa. | to date, 6 tick-borne rickettsiae pathogenic for humans are known to occur in africa and 4 of them were first identified in ticks before being recognized as human pathogens. | 2007 | 17683629 |
ehrlichia species in rhipicephalus sanguineus ticks in cameroon. | ehrlichia and anaplasma species are tick-transmitted obligately intracellular bacteria that commonly cause disease in dogs worldwide. in addition to causing disease in canines, ehrlichia chaffeensis, ehrlichia ewingii, and anaplasma phagocytophilum are responsible for emerging and life-threatening human zoonoses in the united states. we previously reported a high prevalence of e. canis infection in cameroonian dogs based on serologic and molecular evidence. this study was undertaken to determine ... | 2007 | 17627442 |
molecular typing of isolates of rickettsia rickettsii by use of dna sequencing of variable intergenic regions. | rickettsia rickettsii, the causative agent of rocky mountain spotted fever, is found throughout the americas, where it is associated with different animal reservoirs and tick vectors. no molecular typing system currently exists to allow for the robust differentiation of isolates of r. rickettsii. analysis of eight completed genome sequences of rickettsial species revealed a high degree of sequence conservation within the coding regions of chromosomes in the genus. intergenic regions between codi ... | 2007 | 17553977 |
francisella tularensis, portugal. | 2007 | 17561575 | |
q fever (coxiella burnetii) among man and farm animals in north sinai, egypt. | antibodies against coxiella burnetii were estimated among sheep, goats and camels (190), their owners (150 patients with pyrexia of unknown origin) and 30 normal individuals in north sinai over the 2006 by indirect immounofluorescence assay. nested polymerase chain reaction was used to detect com-1 gene (genetic target of c. burnetii) encoding a 27-kda outer membrane protein in the samples. c. burnetii ifa antibodies (igm & igg) in patients were 8 (5.3%) and a healthy control (3.3%). the overall ... | 2007 | 17580573 |
tick acquisition of ehrlichia canis from dogs treated with doxycycline hyclate. | doxycycline generally alleviates clinical monocytic ehrlichiosis, but its efficacy in the control of monocytotropic ehrlichial pathogens requires further investigation. in this study, ehrlichia canis was detected in dogs treated with doxycycline for 14 days and in ticks fed on these dogs, suggesting that treated dogs can remain reservoirs for e. canis. | 2007 | 17606682 |
coinfection with multiple tick-borne and intestinal parasites in a 6-week-old dog. | coinfection with ehrlichia canis, babesia canis, hepatozoon canis, isospora spp., giardia spp., and dipylidium caninum were detected in a 6-week-old dog. the effect of multi-pathogen infection was a fatal combination of gastrointestinal and hematologic abnormalities, including diarrhea, vomiting, anorexia, distended painful abdomen, intussusception, severe thrombocytopenia, anemia, and hypoproteinemia. | 2007 | 17616060 |
prevalence of ehrlichia canis (rickettsiales: anaplasmataceae) in dogs and rhipicephalus sanguineus (acari: ixodidae) ticks from brazil. | the current study evaluated the prevalence of ehrlichia canis donatien and lestoquard in domestic dogs, canis familiaris l., and rhipicephalus sanguineus (latreille) (acari: ixodidae) ticks from different areas of brazil. in monte negro county (state of rondônia, brazilian western amazon), the indirect immunofluorescence assay detected e. canis-reactive antibodies (titer > or = 40) in 58/153 (37.9%) and 40/161 (24.8%) dogs from the urban and rural areas, respectively. these values were significa ... | 2007 | 17294930 |
detection of rickettsia rickettsii and bartonella henselae in rhipicephalus sanguineus ticks from california. | sixty-two questing adult rhipicephalus sanguineus (latreille) ticks were collected by direct removal from blades of turfgrass and adjacent concrete walkways at a suburban home in riverside county, ca, and tested for the presence of rickettsia, bartonella, and ehrlichia dna. polymerase chain reaction (pcr) was used to amplify fragments of the 17-kda antigen gene and the rompa gene of the spotted fever group rickettsiae. one male tick contained r. rickettsii dna; its genotype differed from r. rick ... | 2007 | 17294935 |
uninfected mosquito bites confer protection against infection with malaria parasites. | despite decades of research and multiple initiatives, malaria continues to be one of the world's most debilitating infectious diseases. new insights for malaria control and vaccine development will be essential to thwart the staggering worldwide impact of this disease (a. bjorkman and a. bhattarai, acta trop. 94:163-169, 2005); ultimately successful vaccine strategies will undoubtedly be multifactorial, incorporating multiple antigens and targeting diverse aspects of the malaria parasites' biolo ... | 2007 | 17339356 |
differential interaction of dendritic cells with rickettsia conorii: impact on host susceptibility to murine spotted fever rickettsiosis. | spotted fever group rickettsioses are emerging and reemerging infectious diseases, some of which are life-threatening. in order to understand how dendritic cells (dcs) contribute to the host resistance or susceptibility to rickettsial diseases, we first characterized the in vitro interaction of rickettsiae with bone marrow-derived dcs (bmdcs) from resistant c57bl/6 (b6) and susceptible c3h/hen (c3h) mice. in contrast to the exclusively cytosolic localization within endothelial cells, rickettsiae ... | 2007 | 17403875 |
real-time pcr investigation of potential vectors, reservoirs, and shedding patterns of feline hemotropic mycoplasmas. | three hemotropic mycoplasmas have been identified in pet cats: mycoplasma haemofelis, "candidatus mycoplasma haemominutum," and "candidatus mycoplasma turicensis." the way in which these agents are transmitted is largely unknown. thus, this study aimed to investigate fleas, ticks, and rodents as well as saliva and feces from infected cats for the presence of hemotropic mycoplasmas, to gain insight into potential transmission routes for these agents. dna was extracted from arthropods and from rod ... | 2007 | 17468284 |
experimental infection of dairy calves with ehrlichia chaffeensis. | human monocytic ehrlichiosis (hme) is a zoonotic emerging tick-borne disease with clinical signs that range from mild symptoms to multiple organ failure and death. ehrlichia chaffeensis, the aetiologic agent of hme, is reported to infect a divergent range of mammals. although cattle are common hosts of the primary vector of this pathogen, the susceptibility of this host to e. chaffeensis has not been reported to date. this study was undertaken to determine if cattle could provide a useful infect ... | 2007 | 18033836 |
lateral gene transfer between obligate intracellular bacteria: evidence from the rickettsia massiliae genome. | rickettsia massiliae is a tick-borne obligate intracellular alpha-proteobacteria causing spotted fever in humans. here, we present the sequence of its genome, comprising a 1.3-mb circular chromosome and a 15.3-kb plasmid. the chromosome exhibits long-range colinearity with the other spotted fever group rickettsia genomes, except for a large fragment specific to r. massiliae that contains 14 tra genes presumably involved in pilus formation and conjugal dna transfer. we demonstrate that the tra re ... | 2007 | 17916642 |
confirmation of the efficacy of a novel formulation of metaflumizone plus amitraz for the treatment and control of fleas and ticks on dogs. | a novel spot-on formulation containing metaflumizone plus amitraz (promeris/promeris duo for dogs, fort dodge animal health, overland park, ks) was evaluated in four laboratory studies to confirm efficacy against fleas and ticks on dogs for 1 month. three different strains of cat flea (ctenocephalides felis felis) and four tick species were used. rhipicephalus sanguineus and dermacentor variabilis were evaluated concurrently in two studies and ixodes scapularis and amblyomma americanum in one st ... | 2007 | 17923330 |
dose determination of a novel formulation of metaflumizone plus amitraz for control of cat fleas (ctenocephalides felis felis) and brown dog ticks (rhipicephalus sanguineus) on dogs. | a novel spot-on formulation containing metaflumizone and amitraz (promeris/promeris duo for dogs, fort dodge animal health, overland park, ks) was evaluated in a laboratory study to determine the appropriate dose for efficacy against fleas and ticks on dogs for 1 month. thirty-six beagles were randomly allocated to six equal groups and individually housed. one group remained nontreated. another was treated with a placebo formulation (solvents with no active ingredients). three groups of dogs wer ... | 2007 | 17931781 |
ticks and associated pathogens collected from domestic animals in the netherlands. | following an outbreak of autochthonous canine babesiosis in the netherlands, a request made to veterinarians and the public to collect ticks from companion animals resulted in 4298 ticks submitted between july 2005 and october 2006 to our center. ticks were identified as ixodes ricinus adults (2907/4298, 67.6%), ixodes sp. nymphs (529/4298, 12.3%) and ixodes sp. larvae (385/4298, 9.0%), i. hexagonus adults (328/4298, 7.6%), dermacentor reticulatus (72/4298, 1.7%), and several other exotic tick s ... | 2007 | 17979540 |
localization and visualization of a coxiella-type symbiont within the lone star tick, amblyomma americanum. | a coxiella-type microbe occurs at 100% frequency in all amblyomma americanum ticks thus far tested. using laboratory-reared ticks free of other microbes, we identified the amblyomma-associated coxiella microbe in several types of tissue and at various stages of the life cycle of a. americanum by 16s rrna gene sequencing and diagnostic pcr. we visualized amblyomma-associated coxiella through the use of a diagnostic fluorescence in situ hybridization (fish) assay supplemented with pcr-based detect ... | 2007 | 17720830 |
rickettsia conorii israeli tick typhus strain isolated from rhipicephalus sanguineus ticks in portugal. | this report describes the first establishment of five isolates of r. conorii israeli tick typhus (itt) strain from rhipicephalus sanguineus ticks in different regions of portugal. ticks were collected on two separate expeditions that took place in bragança, montesinho natural park, and portalegre city. | 2007 | 17767403 |
screening dogs in ontario for borrelia burgdorferi and ehrlichia canis should be selective rather than routine. | 2007 | 17824154 | |
anaphylactic shock caused by tick (rhipicephalus sanguineous). | 2007 | 17694706 | |
man-threatening viruses isolated from ticks in saudi arabia. | to determine tick viruses transmissible to man in saudi arabia. | 2007 | 18060218 |
tick fauna from two locations in the brazilian savannah. | the cerrado is brazil's tropical savannah, which is arguably under greater threat than the amazon rainforest. the cerrado biome of tropical south america covers about 2 million km(2) and is considered a biodiversity hot spot which means that it is especially rich in endemic species and particularly threatened by human activities. the cerrado is increasingly exposed to agricultural activities which enhance the likelihood of mixing parasites from rural, urban and wildlife areas. information about ... | 2007 | 17828441 |
movement of rhipicephalus sanguineus adults between co-housed dogs during active feeding. | adult male ticks have been shown capable of experimental acquisition and transmission of tick-borne pathogens without requiring a molt. to determine the ecological relevance of this intrastadial transmission route, we evaluated the extent to which actively feeding male rhipicephalus sanguineus move naturally between co-housed infested dogs. dogs (n=4) were infested with single color-coded ticks, individually housed in tick-confinement cages for 48 h while infestations established, and then each ... | 2007 | 17904292 |
life cycles of seven ixodid tick species (acari: ixodidae) under standardized laboratory conditions. | studies of transmission, maintenance, infectivity, virulence, and pathogenicity of tick-borne agents require the use of large numbers of live laboratory-raised ticks. colonies of ixodes scapularis say, ixodes pacificus cooley & kohls, amblyomma americanum (l.), dermacentor occidentalis marx, dermacentor variabilis (say), hemaphysalis leporispalustris (packard), and rhipicephalus sanguineus (latrielle) have been maintained in our laboratory at the centers for disease control and prevention for fi ... | 2007 | 17915502 |
[a descriptive epidemiological study on canine babesiosis in the lake geneva region]. | a descriptive study was carried out in the district of the lake geneva between march 1, 2005 and august 31,2006 to assess the incidence and prevalence of canine babesiosis, to genotype the babesia species occurring, to assess the most frequently clinical signs found and to address the potential of autochthonous transmission. this included a data assessment on the different tick-populations occurring in the area and on the prevalence of babesia-dna in these ticks. a total of 56 veterinary practic ... | 2007 | 17983018 |
animal babesiosis: an emerging zoonosis also in italy? | in italy, babesiosis is widespread in several central and southern regions, but few data are available on its presence in most italian areas. in 2004 a project was financed by the miur to investigate on the babesiosis epidemiology in vertebrate and invertebrate hosts, and on the transmission risk for humans in central and northern regions of the country. microscopy and/or molecular tools were applied to blood samples of wild animals, livestock and pets, and to 1,677 ticks collected on animals or ... | 2007 | 17691605 |
epidemiological features of mediterranean spotted fever, murine typhus, and q fever in split-dalmatia county (croatia), 1982-2002. | we determined the epidemiological features of three zoonoses in hospitalized patients in southern croatia. patients were diagnosed by serological testing. clinical and epidemiological data were also collected. between 1982 and 2002, mediterranean spotted fever (msf) was diagnosed in 126 (incidence rate 1.27/100,000 per year), murine typhus (mt), in 57 (incidence rate 0.57/100,000 per year), and q fever in 170 (incidence rate 1.7/100,000 per year) patients. msf and q fever were characterized by a ... | 2007 | 17850690 |
in vitro isolation and molecular characterization of an ehrlichia canis strain from são paulo, brazil. | an ehrlichia canis isolate was obtained from an naturally infected dog exhibiting clinical signs of ehrlichiosis in são paulo municipality, state of são paulo, brazil. the isolate was characterized by pcr and dna sequencing of portions of the ehrlichial genes dsb, 16srrna, and p28. partial dsb and 16s rrna sequences were identical to three and five other e. canis strains, respectively, from different countries and continents (including north america, africa, asia and europe). conversely, the p28 ... | 2008 | 24031251 |
reliminary survey of ticks (acari: ixodidae) on cattle in central equatoria state, southern sudan. | in a preliminary survey conducted in 2005, the species composition and seasonality of ticks infesting cattle in central equatoria state, southern sudan was determined. three locations were selected (gumbo, khor rumla and nyaing) and surveyed every 3 months. two cattle herds in each of the three locations were visited four times during the study period. total body collections of ticks were made from each of five cattle (nilotic zebu breed) kept in six different herds. four tick genera and ten spe ... | 2008 | 18575063 |
efficacy of a single application of a 12.5% pyriprole topical solution against laboratory infestations with ticks (ixodes ricinus, dermacentor reticulatus, and rhipicephalus sanguineus) on dogs. | in three separate studies, the efficacy of a single treatment with a 12.5% pyriprole spot-on solution was investigated against induced infestation with ixodes ricinus, dermacentor reticulatus and rhipicephalus sanguineus on dogs (both sexes; beagles in studies 1 and 2, mixed-breed in study 3). for each tick species, one group of 8 dogs left untreated (studies 1 and 2) or treated with a placebo solution (study 3) was compared with another group treated once with the spot-on solution at a dose rat ... | 2008 | 18455315 |
genetic and antigenic diversities of major immunoreactive proteins in globally distributed ehrlichia canis strains. | the extent of knowledge regarding the diversity of globally distributed ehrlichia canis strains has been limited to information gained from a few evolutionarily conserved genes. in this study, e. canis strains from the united states (strain jake [us]), brazil (strain são paulo [br]), and israel (strain 611 [is] and ranana [is-r]) were used to examine the antigenic and genetic diversities of four well-characterized major immunoreactive protein genes/proteins. gp36 and gp200 were the most divergen ... | 2008 | 18480237 |
[control of rhipicephalus sanguineus (latrielle, 1806) (acari: ixodidae) in the kennel of the ufmg veterinary school, belo horizonte, minas gerais, brazil]. | the present work was aimed at proposing a control measure for rhipicephalus sanguineus in a naturally infected kennel of 72 m(2) of the ufmg veterinary school with 25 dogs of different breeds. a sensitivity test to acaricide products was applied in a sample of r. sanguineus. out of the acaricide products tested: 12.5% amitraz (product 1); 2% alfamethrin and 60% dichlorvos association (product 2); 5% deltamethrin (product 3) and the association between 77.6% trichlorfon, 1.0% coumaphos and 1.0% c ... | 2008 | 18554440 |
ticks infesting domestic animals in northern greece. | the tick species infesting grazing animals in the countryside of 11 prefectures in northern greece were investigated during april-july and september-december of consecutive years 2003-2006. a total of 3,249 (1,952 males, 1,297 females) adult ticks were collected from goats, sheep, cattle and dogs. ticks were identified as ixodes ricinus (44.57%), ixodes gibbosus (4.09%), rhipicephalus bursa (19.14%), rhipicephalus sanguineus, rhipicephalus turanicus (5.79%), hyalomma marginatum marginatum (12.40 ... | 2008 | 18563592 |
anaphylactic shock caused by tick bites. | 2008 | 18564642 | |
molecular survey of rickettsia spp. in sick dogs in italy. | the aim of this retrospective study was to investigate the prevalence of rickettsia spp. dna in the blood of sick dogs from italy. canine blood samples (n=650) submitted for molecular testing of rickettsia spp. to a diagnostic laboratory from february 2003 to march 2006 were studied. the rickettsia spp. dna detection was performed by light cycler real-time pcr using hybridization probes separately conducted with specific primers and probes. the total percentage of rickettsia spp.-positive dog sa ... | 2008 | 18631232 |
[characterization of ectoparasites on dogs in the nucleus of urban expansion of juiz de fora, minas gerais, brazil]. | the present work studied the characterization of ectoparasites on dogs in the nucleus of urban expansion of juiz de fora, minas gerais, brazil. the collections were conducted from july to september 2003, examining 101 dogs of no defined breed. the ectoparasites were collected through visual and tactile inspection of the animals' bodies, and were then placed in bottles with 70 degrees gl ethanol and identified under a stereomicroscope. specimens were clarified and mounted on slides for analysis u ... | 2008 | 19265575 |
first direct detection of rickettsial pathogens and a new rickettsia, 'candidatus rickettsia barbariae', in ticks from sardinia, italy. | the present study evaluated the molecular detection and identification of rickettsia species in 83 ticks collected in sardinia, italy. fifteen ticks were pcr-positive using glta-specific and ompa-specific primers, leading to the identification of rickettsia aeschlimannii in hyalomma marginatum marginatum, r. massiliae in rhipicephalus turanicus and in rhipicephalus sanguineus, and a new rickettsia, previously referred to as potirb169 in portugal, in four rhipicephalus turanicus. this new species ... | 2008 | 19040474 |
ectoparasites on reintroduced roe deer capreolus capreolus in israel. | the ectoparasite fauna of reintroduced roe deer (capreolus capreolus) was surveyed in a mediterranean forest in israel. ectoparasites were collected from four female hand-reared deer during 2004 and 2005. seasonality, predilection sites of infestation, and the apparent effect of the parasites are presented. this is the first study of roe deer parasites in the east mediterranean. the ectoparasite fauna included three hippoboscid fly (lipoptena capreoli, hippobosca equina, and hippobosca longipenn ... | 2008 | 18689655 |
questions on mediterranean spotted fever a century after its discovery. | mediterranean spotted fever (msf) was first described in 1910. twenty years later, it was recognized as a rickettsial disease transmitted by the brown dog tick. in contrast to rocky mountain spotted fever (rmsf), msf was thought to be a benign disease; however, the first severe case that resulted in death was reported in france in the 1980s. we have noted important changes in the epidemiology of msf in the last 10 years, with emergence and reemergence of msf in several countries. advanced molecu ... | 2008 | 18760001 |
the effect of temperature and fasting period on the viability of free-living females of rhipicephalus sanguineus (acari: ixodidae) under laboratory conditions. | little is known about the effect of temperature on viability of free-living phases of the life cycle of rhipicephalus sanguineus (latreille, 1806) despite of its importance as vector of several pathogens. knowledge of the effect of abiotic factors on the capacity of a given tick species to infest new hosts is important for routine experimental activities under laboratory conditions, and may be relevant to understand the transmission of pathogens. the study evaluates the viability of r. sanguineu ... | 2008 | 18566896 |
absence of wolbachia endobacteria in the non-filariid nematodes angiostrongylus cantonensis and a. costaricensis. | abstract: the majority of filarial nematodes harbour wolbachia endobacteria, including the major pathogenic species in humans, onchocerca volvulus, brugia malayi and wuchereria bancrofti. these obligate endosymbionts have never been demonstrated unequivocally in any non-filariid nematode. however, a recent report described the detection by pcr of wolbachia in the metastrongylid nematode, angiostrongylus cantonensis (rat lungworm), a leading cause of eosinophilic meningitis in humans. to address ... | 2008 | 18801163 |
rickettsia conorii transcriptional response within inoculation eschar. | rickettsia conorii, the causative agent of the mediterranean spotted fever, is transmitted to humans by the bite of infected ticks rhipicephalus sanguineus. the skin thus constitutes an important barrier for the entry and propagation of r. conorii. given this, analysis of the survival strategies used by the bacterium within infected skin is critical for our understanding of rickettsiosis. | 2008 | 18997861 |
a review of the off-label use of selamectin (stronghold/revolution) in dogs and cats. | since its introduction approximately seven years ago, selamectin (stronghold/revolution, pfizer inc.) has been used off-label to treat a number of ecto- and endoparasite conditions in dogs and cats. it has been used as a successful prophylactic against dirofilaria repens and as a treatment for aelurostrongylus abstrusus in cats. it has also been used to treat notoedric mange, infestation with the nasal mite pneumonyssoides caninum, cheyletiella spp. and neotrombicula autumnalis infestations and ... | 2008 | 19032763 |
antibiotic clearance of ehrlichia canis from dogs infected by intravenous inoculation of carrier blood. | ehrlichia canis is the etiologic agent of canine monocytic ehrlichiosis (cme) and is a useful model for zoonotic tick-borne pathogens, many of which infect dogs. the purpose of this study was to evaluate rifampin and doxycycline regimens for clearance of e. canis infections in addition to alleviation of cme. beagles were infected with e. canis by intravenous inoculation with carrier blood and treated with either rifampin or doxycycline after the acute phase of cme. improved hematological values ... | 2008 | 19120226 |
mediterranean spotted fever. | rickettsial disease has recently undergone an important evolution, particularly in the field of molecular genetics. this development includes mediterranean spotted fever (msf), a tick-borne disease caused by rickettsia conorii. important changes have occurred in ecologic and epidemiologic comprehension of the disease, and in the occurrence of severe forms. however, many questions still remain, including the identity of the real vector and reservoir of r conorii, and whether other risk factors ex ... | 2008 | 18755388 |