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endophytic fungus purpureocillium sp. a5 protect mangrove plant kandelia candel under copper stress.mangrove is an important ecosystem in the world. mangrove ecosystems have a large capacity in retaining heavy metals, and now they are usually considered as sinks for heavy metals. however, the mechanism of why the soil of mangrove ecosystems can retain heavy metal is not certain. in this research, endophytic fungus purpureocillium sp. a5 was isolated and identified from the roots of kandelia candel. when this fungus was added, it protected the growth of k. candel under cu stress. this can be il ...201728237674
keratitis by paecilomyces lilacinus: a case report from sub-himalayan region.paecilomyces lilacinus is a filamentous fungus found in soil and air, which is a rare cause of ocular infection. the majority of case reports involving p. lilacinus among healthy hosts are of endophthalmitis and keratitis. we report a rare case of keratomycosis by p. lilacinus, in an immunocompetent, which responded well to treatment with ketoconazole. some species belonging to the genus paecilomyces such as p. lilacinus generally shows a poor response to conventional antifungal drugs. therefore ...201526470971
improvement of the insecticidal capacity of two purpureocillium lilacinum strains against tribolium confusum.entomopathogenic fungi can regulate insect populations. they have extracellular enzymes that degrade cuticle components, mainly hydrocarbons, used as an energy source. the increase in insecticidal activity of fungi in a medium supplemented with cuticular hydrocarbons was assayed and the hydrolytic enzyme profiles of two strains of purpureocillium lilacinum were evaluated. a spore suspension of p. lilacinum was inoculated in petri plates with different values (0.99-0.97-0.95) of water activity (a ...201526463076
in vitro screening and in silico validation revealed key microbes for higher production of significant therapeutic enzyme l-asparaginase.l-asparaginase is an enzyme of medical prominence and reputable as a chemotherapeutic agent. it also has immense potential to cure autoimmune and infectious diseases. the vast application of this enzyme in healthcare sector increases its market demand. however, presently the huge market demand is not achieved completely. this serves the basis to explore better producer microbial strains to bridge the gap between huge demand and supply of this therapeutic enzyme. the present study deals with the ...201728110669
[stress resistance mechanisms in the indicator fungi from highly radioactive chernobyl zone sites].comparison of the levels of the protein carboxylic groups in response to peroxide stress revealed enhanced stress resistance in purpureocillium lilacinum strains isolated from soils with high content of copper or radionuclides compared to the strains isolated from uncontaminated soils. while in background strains resistance to peroxide stress increased with glucose content in the medium increasing from 0.002 to 2%, the strains from radionuclides- or copper-contaminated soils did not exhibit this ...201526263624
purpureocillium lilacinum, potential agent for biological control of the leaf-cutting ant acromyrmex lundii.many leaf-cutter ant species are well known pests in latin america, including species of the genera acromyrmex and atta. an environmentally friendly strategy to reduce the number of leafcutter ants and avoid indiscriminate use of chemical pesticides is biological control. in this work we evaluated the effectiveness of a strain of the entomopathogen purpureocillium lilacinum, against worker ants from six acromyrmex lundii field colonies, after immersions in pure suspensions at a concentration of ...201526205173
a comparative study on the biosorption of cd2+ onto paecilomyces lilacinus xla and mucoromycote sp. xlc.the filamentous fungi xla and xlc isolated from cd-contaminated soil were identified morphologically and phylogenetically as paecilomyces lilacinus and mucoromycote sp., respectively. the minimum inhibitory concentrations (mics) of cd2+, co2+, cu2+, zn2+, cr3+ and cr6+ in minimum mineral (mm) medium agar plates were 29,786, 2945, 9425, 5080, 1785 and 204 mg · l(-1) for xla and 11,240, 884, 9100, 2540, 3060 and 51 mg · l(-1) for xlc, respectively. favorable biosorption conditions for adsorption o ...201526184169
use of voriconazole for the treatment of paecilomyces lilacinus cutaneous infections: case presentation and review of published literature.the fungus paecilomyces lilacinus is a rare but emerging pathogen that causes severe human infections, especially in immunocompromised hosts. it is an important organism to identify due to its poor susceptibility to conventional antifungal drugs, including amphotericin b, itraconazole, and fluconazole. oculomycosis and cutaneous infections are the two most common manifestations of p. lilacinus infections. voriconazole has been used successfully to treat p. lilacinus endophthalmitis, but reports ...201323334554
isaria takamizusanensis is the anamorph of cordyceps ryogamimontana, warranting a new combination, purpureocillium takamizusanense comb. nov.the entomogenous anamorphic fungus isaria takamizusanensis has not been resolved clearly in its teleomorphic state. we succeeded in inducing ascostroma formation by incubating conidiomata of i. takamizusanensis on cicada adults in a moist chamber. we observed the ascostroma and conducted a phylogenetic analysis based on its rdna and ef-1α genes. the morphology of the ascostroma was identical to that of cordyceps ryogamimontana. in the phylogenetic tree inferred from ef-1α, the isolate from the p ...201525911534
spatial relationships between entomopathogenic nematodes and nematophagous fungi in florida citrus orchards.relationships between entomopathogenic nematodes (epns), nematophagous fungi (nf) and soil physical and chemical properties were studied in a survey of 53 citrus orchards in central ridge and flatwoods ecoregions of florida. seven species of nf associated with nematodes were quantified directly using a real time qpcr assay. all nematophagous fungi studied except arthrobotrys musiformis and hirsutella rhossiliensis were frequently detected (24-56%) in both regions. paecilomyces lilacinus and gams ...201728087206
modulation of paecilomyces lilacinus antimicrobial metabolite production by co-culturing with salmonella typhimurium.fungi are important organisms related to the production of antibiotics, many of which are commercially available and used in the clinic to treat infections. infectious diseases represent a leading cause of death worldwide, being a severe threat to public health, especially with the rise of multi-resistant microorganisms. therefore, the search for new antibiotic substances is regaining importance. the aim of this study was to evaluate the modulation of the antimicrobial activity of paecilomyces l ...201323106630
biodegradation of feather wastes and the purification and characterization of a concomitant keratinase from paecilomyces lilacinus.paecilomyces lilacinus strain pl-hn-16 was found to have the ability to degrade feathers. during the degradation process, the broth initially turned as sticky as gelatin and then turned into fluid that means the feathers can be hydrolyzed completely. keratinolytic protein (ker) of aforementioned strain was purified using ammonium sulphate precipitation, hitrap butyl ff chromatography and sephacryl s-200 gel filtration. the ker of p. lilacinus pl-hn-16 had molecular mass of 33 kda, the optimum ph ...201525757340
contact-lens-associated purpureocillium keratitis: risk factors, microbiologic characteristics, clinical course, and outcomes.to study the risk factors, microbiologic characteristics, clinical course, and outcomes of patients with purpureocillium keratitis at a tertiary eye care center in south florida.201725723808
clinical experience treating paecilomyces lilacinus keratitis in four patients.paecilomyces lilacinus is a saprobic fungus that occasionally causes keratitis in infected patients. voriconazole, a triazole antifungal agent, is often administered to treat p. lilacinus keratitis, because it is resistant to many antifungal agents. however, some patients may not require voriconazole. here, we report our experience of treating this infection and compare outcomes between patients treated with or without voriconazole.201222791978
first report on isolation of penicillium adametzioides and purpureocillium lilacinum from decayed fruit of cheongsoo grapes in korea.two species, penicillium adametzioides and purpureocillium lilacinum, were isolated from decayed grapes (cv. cheongsoo) in korea. each species was initially identified by phylogenetic analysis of a combined dataset of two genes. internal transcribed spacer (its) and β-tubulin (bt2) genes were used for identification of penicillium adametzioides, and its and partial translation elongation factor 1-α (tef) genes were used for identification of purpureocillium lilacinum. morphologically, they were ...201222783137
interaction of an opportunistic fungus purpureocillium lilacinum with human macrophages and dendritic cells.purpureocillium lilacinum is emerging as a causal agent of hyalohyphomycosis that is refractory to antifungal drugs; however, the pathogenic mechanisms underlying p. lilacinum infection are not understood. in this study, we investigated the interaction of p. lilacinum conidia with human macrophages and dendritic cells in vitro.201425467264
fungal jarosite biomineralization in río tinto.río tinto is an extreme environment located at the core of the iberian pyrite belt (ipb). it is an unusual ecosystem due to its size, constant acidic ph, high concentration of heavy metals and a high level of microbial diversity, mainly eukaryotic. recently it was described the biomineralization of jarosite by purpureocillium lilacinum, an acidic filamentous fungi isolated from the banks of the tinto basin. in this study we further investigate the specificity of jarosite biomineralization by thi ...201425445568
keratinophilic fungi isolated from soils of long-term fold-grazed, degraded pastures in national parks of slovakia.a total of 939 isolates of 11 genera representing 15 species of keratinophilic fungi were isolated and identified from the soils of three long-term fold-grazed pastures in national parks of slovakia (pod ploskou, strungový príslop, and pod kečkou) and one non-fold-grazed pasture in sierra stolicke vrchy (diel) using the hair-baiting technique. keratinophilic fungi were present in all soil samples with a prevalence of trichophyton ajelloi and paecilomyces lilacinus. these fungi were more abundant ...201222539211
paecilomyces lilacinus endophthalmitis following cataract surgery: a therapeutic challenge. 201222496026
unusual case of cutaneous and synovial paecilomyces lilacinus infection of hand successfully treated with voriconazole and review of published literature.paecilomyces lilacinus infection is rare and is found worldwide. the majority of infections occur in immunocompromised people. among immunocompetent patients, cutaneous infections are the second most common site of infection but are difficult to treat because of antifungal resistance. we report a case of hand cutaneous involvement with synovitis in an immunocompetent patient that improved after treatment with oral voriconazole. to the best of our knowledge, there are only five published cases of ...201222484831
cutaneous paecilomyces lilacinus infections in immunocompromised and immunocompetent patients: retraction. 201425382539
liquid chromatography-tandem mass spectrometry characterization of five new leucinostatins produced by paecilomyces lilacinus cg-189.the fungus paecilomyces lilacinus produces leucinostatins—peptaibiotics that exert a range of biological activities including antimalarial, antiviral, antitumor and phytotoxicity. in this paper, we developed an analytical method employing lc-ms/ms in the precursor ion and product ion scan modes to elucidate five new leucinostatins. direct infusion (di-ms) helped to identify the most abundant leucinostatins: f, d b2, s, a and k. ms/ms analysis using a triple quadrupole operating at different scan ...201525182486
paecilomyces lilacinus fungaemia in an aids patient: the importance of mycological diagnosis.fungaemia due to paecilomyces lilacinus is generally not considered in aids patients because this condition is not categorised as an aids-indicator illness. we report a case of a 25-year-old lady who presented to our hospital with guillain-barré syndrome, with the subsequent development of refractory fungaemia, multi-organ failure and disseminated intravascular coagulopathy. amphotericin b was given as empirical antifungal therapy. hiv screening was reactive and paecilomyces lilacinus was isolat ...201425097544
spore production in paecilomyces lilacinus (thom.) samson strains on agro-industrial residues.paecilomyces lilacinus has potential for pests control. we aimed to analyze mycelial growth and spore production in p. lilacinus strains in several agro-industrial residues and commercial media. this study suggests alternative nutrient sources for fungi production and that the biotechnological potential of agro-industrial refuses could be employed in byproducts development.200924031361
baeyer-villiger oxidation of dhea, pregnenolone, and androstenedione by penicillium lilacinum am111.the baeyer-villiger monooxygenase (bvmo) produced by penicillium lilacinum am111, in contrast to other enzymes of this group known in the literature, is able to process 3beta-hydroxy-5-ene steroid substrates. transformation of dhea and pregnenolone yielded, as a sole or main product, 3beta-hydroxy-17a-oxa-d-homo-androst-5-en-17-one, a new metabolite of these substrates; pregnenolone was transformed also to testololactone. testololactone was the only product of oxidation of androstenedione by p. ...200818755205
cutaneous paecilomyces lilacinus infections in immunocompromised and immunocompetent patients.paecilomyces is a genus of saprophytic fungus that has been associated, in rare instances, with human disease. we report two cases in which paecilomyces lilacinus was isolated from cutaneous and subcutaneous lesions in an immunocompromised and an immunocompetent host. the first case was a subcutaneous infection due to p. lilacinus in a patient with a renal transplant and diabetes mellitus. the second case was an immunocompetent young woman who developed a cutaneous infection, with no identified ...201625035359
topical voriconazole therapy of purpureocillium lilacinum keratitis that occurred in disposable soft contact lens wearers.the objective of this study was to describe 2 cases of keratitis caused by purpureocillium lilacinum (formerly paecilomyces lilacinus) that occurred in disposable contact lens users, which were successfully treated with topical voriconazole. case 1 was a healthy 44-year-old woman, who wore weekly disposable contact lenses and had developed a superficial corneal infection in her right eye. for diagnosis, corneal scraping and molecular identification of the cultured pathogen were performed. a corn ...201424974133
the action pattern of penicillium lilacinum dextranase.the product distributions resulting from the action of penicillium lilacinum dextranase on end-labelled oligosaccharides of the isomaltose series have been determined. the initial rates of formation of labelled products were measured for isomaltotriose up to isomalto-octaose, and the molar proportions and radioactivity of the final products from isomaltotriose up to isomaltohexaose were determined. d-glucose was released only from isomaltotriose and isomaltotetraose, by hydrolysis of the first l ...19751139551
transformations of steroids by cell-free preparations of penicillium lilacinum nrrl 895. iv. enzyme catalyzed acyl transfer. 19744855237
a new antibiotic, leucinostatin, derived from penicillium lilacinum. 19734783199
[the effect of various inhibitors and activators on proteolytic enzymes formed by penicillium lilacinum thom]. 20134771033
transformations of steroids by cell-free preparations of penicillium lilacinum nrrl 895. 3. metabolism of progesterone during esterase inhibition with clomiphene citrate. 19734784616
transformation of steroids by cell-free preparations of penicillium lilacinum nrrl 895. 2. hydrolysis of steroid esters. 19734784608
enzymic side-chain degradation of progesterone by penicillium lilacinum. 19734781170
nutrition and fat production in submerged cultures of a strain of penicillium lilacinum. 20134686216
pleural effusion caused by penicillium lilacinum. 19725083436
[study of proteolytic enzymes of various strains of penicillium lilacinum thom in relation to their fibrinolytic activity]. 20045044883
side chain degradation and 20-(alpha + beta)-reduction of progesterone by cell free preparations of penicillium lilacinum nrrl 895. 19725049649
side chain degradation of epimeric 20-hydroxy-4-pregnene-3-ones by penicillium lilacinum nrrl 895. 19705487820
the utilization of some egyptian by-products for the microbiological production of fat by penicillium lilacinum. 19695382796
intermediates in the metabolism of steroids by penicillium lilacinum.sebek, oldrich k. (the upjohn company, kalamazoo, mich.), lester m. reineke, and durey h. peterson. intermediates in the metabolism of steroids by penicillium lilacinum. j. bacteriol. 83:1327-1331. 1962-nonproliferating cells of penicillium lilacinum (thom) metabolized progesterone successively to 20-beta-hydroxy-4-pregnen-3-one, testosterone, androstenedione, and testololactone. testosterone and androstenedione were readily interconvertible. 11-alpha-hydroxyprogesterone was transformed in an an ...196216561948
kinetic modelling of thermal inactivation of a keratinase from purpureocillium lilacinum lpsc # 876 and the influence of some additives on its thermal stability.thermal inactivation of a keratinase produced by purpureocillium lilacinum lpsc #876 was kinetically investigated using several enzyme inactivation models at the temperature range of 50-65 °c. among the models studied, the weibull distribution was the best model that describes the residual activity of p. lilacinum keratinase after heat treatment over the selected temperatures. the stabilising effect of metal ions (ca2+ or mg2+, 5 mmol l(-1)) or polyols (propylene glycol and glycerol, 10% v/v) wa ...201424916805
successful treatment of paecilomyces lilacinus keratitis with oral posaconazole.to report a case of successful medical treatment with oral posaconazole in refractory fungal keratitis caused by paecilomyces lilacinus.201424858020
the use of acetate in the metabolism of penicillium lilacinum thom. particularly in relation to synthesis of fat. 195914425803
pantothenic acid in relation to the fat-forming mould: penicillium lilacinum thom. 195914425802
effect of riboflavin and nicotinic acid on fat formation by penicillium lilacinum thom. 195813524209
the component fatty acids of penicillium lilacinum fat. 195613293176
[eye infections caused by purpureocillium lilacinum: a case report and literature review].purpureocillium lilacinum eye infections (previously called paecilomyces lilacinus) make up a significant percentage of the recorded cases of infection by this fungus, and is considered as an emerging pathogen.201524793075
role of karanja deoiled cake based medium in production of protease and fatty acids by paecilomyces lilacinus 6029.protease and fatty acids are known to serve as pathogenic factors against root-knot nematodes. here, we utilized karanja deoiled cake as a nitrogen source for the first time in induction of protease by paecilomyces lilacinus. fatty acids, especially butyric acid, have also been detected in the same fungal culture filtrate.201424704176
studies on pva pectin cryogels containing crosslinked enzyme aggregates of keratinase.polyvinyl alcohol-pectin (pva-p) films containing enrofloxacin and keratinase were developed to treat wounds and scars produced by burns and skin injuries. however, in order to prevent enzyme inactivation at the interface between the patch and the scars, crosslinked enzyme aggregates (cleas) from a crude extract of keratinase produced by paecilomyces lilacinus (lpsc#876) were synthesized by precipitation with acetone and crosslinking with glutaraldehyde. soluble vs. clea keratinase (k-clea) acti ...201424657614
culture-proven thorn-associated infections in arizona: 10-year experience at mayo clinic.thorn injuries are common in the desert southwest; however, the frequency and microbiology of thorn-associated infections have not been systematically described. most information comes from case reports describing infections from atypical or environmental microorganisms. our aim was to summarize the spectrum of thorn-associated infections.201728480288
a rare case of nasal septal perforation due to purpureocillium lilacinum: case report and review.perforations of nasal septum are fairly frequent with an incidence of about 0.9 % and may lead to morbidity than mortality. common causes are trauma (iatrogenic occasionally nose picking), malignancy, inflammations and infections such as tuberculosis, syphilis, wegener's granulomatosis, sarcoidosis and fungal infections. paranasal fungal sinusitis is frequently encountered in clinical practice in both immunocompromised and immunocompetent individuals. nasal septal perforations caused by species ...201324427563
multiple gene genealogical analyses of a nematophagous fungus paecilomyces lilacinus from china.paecilomyces lilacinus is a geographically widespread nematophagous fungus and a promising biological control agent against plant parasitic nematodes. however, relatively little is known about its patterns of genetic variation through its broad geographic and ecological contexts. in this study, we analyzed the genetic variation of 2 virulence-associated genes (pls and plc) and 4 housekeeping gene fragments (its, rpb1, rpb2, and β-tubulin) among 80 p. lilacinus specimens collected from 7 location ...201323990292
absolute configuration of acremoxanthone c, a potent calmodulin inhibitor from purpureocillium lilacinum.bioassay-guided fractionation of an extract prepared from the culture medium and mycelium of purpureocillium lilacinum allowed the isolation of two calmodulin (cam) inhibitors, namely, acremoxanthone c (1) and acremonidin a (2). the absolute configuration of 1 was established as 2r, 3r, 1's, 11's, and 14'r through extensive nmr spectroscopy and molecular modeling calculations at the dft b3lyp/dgdzvp level, which included the comparison between theoretical and experimental specific rotation, ³j(c ...201323876004
detection of antibody to purpureocillium lilacinum by immunofluorescent assay and flow cytometry in serum of infected c57bl/6 mice.purpureocillium lilacinum is an emerging pathogenic fungus that can cause different clinical manifestations ranging from cutaneous and sub-cutaneous infections to severe oculomycosis. in this study, using both conventional indirect immunofluorescence and non-conventional flow cytometry approaches, igg antibodies were readily detected in both c57bl/6 immunocompetent and immunosuppressed mice after i.v. infection with p. lilacinum. the humoral immune response was specific, since virtually no antib ...201323872615
enzymatic hydrolysis of gelatin layers of x-ray films and release of silver particles using keratinolytic serine proteases from purpureocillium lilacinum lps # 876.enzymatic decomposition of gelatin layers on used x-ray films and repeated utilization of the enzyme for potential application in silver recovery were investigated using keratinolytic serine proteases from purpureocillium lilacinum lps # 876. at ph 9.0, the enzymatic reaction was enhanced by the increase of enzyme concentration or by the increase of the temperature up to 60℃. under the conditions of 6.9 u/ml, 60℃, and ph 9.0, hydrolysis of the gelatin layers and the resulting release of silver p ...201323727808
study of the production of alkaline keratinases in submerged cultures as an alternative for solid waste treatment generated in leather technology.six nonpathogenic fungal strains isolated from alkaline soils of buenos aires province, argentina (acremonium murorum, aspergillus sidowii, cladosporium cladosporoides, neurospora tetrasperma, purpureocillium lilacinum (formerly paecilomyces lilacinus), and westerdikella dispersa) were tested for their ability to produce keratinolytic enzymes. strains were grown on feather meal agar as well as in solid-state and submerged cultures, using a basal mineral medium and "hair waste" as sole sources of ...201323711525
immobilized keratinase and enrofloxacin loaded on pectin pva cryogel patches for antimicrobial treatment.a keratinase isolated from paecilomyces lilacinus (lps #876) was tested against proteins present in the skin but the high enzyme activity was detected on collagen. keratinase was physically immobilized onto pva-pectin cryogels and enzyme release was 20.8±2.1%, 63.8±0.2%, 41.5±3.5% and 26.0±3.5% in cryogels containing pectins with esterification degrees (de) 33.0%, 55.0%, 62.7% and 71.7% respectively at 37°c after 3h incubation. in presence of 0.75 m nacl, the percentage of enzyme release changed ...201323558181
specific jarosite biomineralization by purpureocillium lilacinum, an acidophilic fungi isolated from río tinto.río tinto (huelva, southwestern spain) is an extreme environment with a remarkably constant acidic ph and a high concentration of heavy metals, conditions generated by the metabolic activity of chemolithotrophic microorganisms thriving in the rich complex sulfides of the iberian pyrite belt (ipb). fungal strains isolated from the tinto basin were characterized morphologically and phylogenetically. the strain identified as purpureocillium lilacinum specifically induced the formation of a yellow-o ...201323425574
cutaneous hyalohyphomycosis caused by purpureocillium lilacinum in an immunocompetent patient: case report and review.purpureocillium lilacinum is a saprophytic fungus found in soil and decaying organic matter, but has been reported as an emerging pathogen in immunocompromised patients and following surgical procedures. infections caused by this mold are often difficult to treat because of its intrinsic resistance to conventional antifungal agents and variable susceptibility to novel triazoles. in immunocompetent subjects, infections caused by p. lilacinum are unusual and mainly involve the skin. we describe he ...201323330674
paecilomide, a new acetylcholinesterase inhibitor from paecilomyces lilacinus.fungi are some of the most important organisms in the production of bioactive secondary metabolites. this success is related to the advances in biotechnology and also to the possibility of working with techniques such as the "osmac" (one strain-many compounds) to achieve different fungal secondary metabolites profiles upon modifying the culturing conditions. using this approach, the fungal species paecilomyces lilacinus was cultivated in potato dextrose broth under 14 different fermentative cond ...201323219197
management of recurrent paecilomyces lilacinus keratitis.a 72-year-old man presented with paecilomyces keratitis subsequent to immunosuppressive treatment. despite medical therapy with voriconazole, perforation occurred requiring a tectonic keratoplasty of 10 mm. despite oral, topical and intracameral voriconazole, there was recurrent stromal infiltration. a corneoscleral graft of 15 mm was undertaken. two weeks later, hyphae were seen on the anterior lens capsule with hypopyon requiring phacoemulsification and anterior chamber washout. six weeks late ...201322925066
polyphasic analysis of purpureocillium lilacinum isolates from different origins and proposal of the new species purpureocillium lavendulum.purpureocillium is a genus recently proposed to accommodate paecilomyces lilacinus, a well studied species that has biotechnological properties and an ability to cause human infections. since contradictory data have been reported on the intraspecific genetic variability of p. lilacinum, we have carried out a polyphasic study of a set of clinical and environmental isolates of this species. detailed morphological examination and sequence analysis of four different loci, including the ribosomal int ...201322893638
paecilomyces lilacinus peritonitis in a peritoneal dialysis patient. 201322641749
biodegradation of a keratin waste and the concomitant production of detergent stable serine proteases from paecilomyces lilacinus.paecilomyces lilacinus (lps 876) efficiently degraded keratin in chicken feather during submerged cultivation producing extracellular proteases. characterization of crude protease activity was done including its compatibility in commercial detergents. optimum ph and temperature were 10.0 and 60 °c, respectively. protease activity was enhanced by ca²⁺ but was strongly inhibited by pmsf and by hg²⁺ suggesting the presence of thiol-dependent serine proteases. the crude protease showed extreme stabi ...201222447221
paecilomyces lilacinus causing debilitating sinusitis in an immunocompetent patient: a case report.since the discovery of the first documented case of paecilomyces in 1963, only five cases of paecilomyces sinusitis have been described to date and all of them have predisposing factors such as immunocompromised status or prior nasal surgery. we present the first case of paecilomyces lilacinus sinusitis in a fit young woman with no identified predisposing factors. to the best of our knowledge, this is the first known case in the uk and in europe.201222443718
purpureocillium lilacinum as a cause of cavitary pulmonary disease: a new clinical presentation and observations on atypical morphologic characteristics of the isolate.the first case of cavitary pulmonary disease caused by purpureocillium lilacinum is described. the isolate showed atypical microscopic characteristics similar to acremonium and fusarium spp., which necessitated molecular identification by sequencing of multiple conserved loci. the patient responded to voriconazole, reinforcing its therapeutic efficacy for p. lilacinum infections.201222322350
a simple method for isolation of high-molecular-weight dna from rhodotorula gracilis.unsheared dna has been isolated from rhodotorula and rhodosporidium yeasts using a cell-wall-digesting enzyme preparation from paecilomyces lilacinus. pulsed-field gel electrophoresis indicated that at least 11 chromosomes were present in rhodot. gracilis atcc 90950. the dna was amenable to digestion with restriction enzymes.199524414650
effect of different factors on progesterone side chain degrading enzymes of penicillium lilacinum. 1977606662
growth and metabolism of penicillium lilacinum thom. with reference to the effects of riboflavin and nicotinic acid. 196014425800
influence of thiamin on growth and fat formation by penicillium lilacinum thom. 195914425801
in vitro assay of paecilomyces lilacinus biocontrol effects on fasciola hepatica eggs illustrated in scanning electron micrographs.fascioliasis is a zoonotic disease caused by the liver fluke fasciola hepatica. drug resistance, high costs of treatment and economic losses in meat production have emerged the need of alternative control measures into consideration. the aim of this study was to evaluate the in vitro ovicidal activity of paecilomyces lilacinus fungus on f. hepatica eggs.201728761457
evaluation of pochonia chlamydosporia and purpureocillium lilacinum for suppression of meloidogyne enterolobii on tomato and banana.meloidogyne enterolobii is one of the most important root-knot nematode in tropical regions, due to its ability to overcome resistance mechanisms of a number of host plants. the lack of new and safe active ingredients against this nematode has restricted control alternatives for growers. egg-parasitic fungi have been considered as potential candidates for the development of bionematicides. in tissue culture plates, pochonia chlamydosporia (var. catenulata and chlamydosporia) and purpureocillium ...201728512379
management of root-knot nematode (meloidogyne incognita) on pittosporum tobira under greenhouse, field, and on-farm conditions in florida.root-knot nematodes are important pests of cut foliage crops in florida. currently, effective nematicides for control of these nematodes on cut foliage crops are lacking. hence, research was conducted at the university of florida to identify pesticides or biopesticides that could be used to manage these nematodes. the research comprised on-farm, field, and greenhouse trials. nematicide treatments evaluated include commercial formulations of spirotetramat, furfural, and purpureocillium lilacinum ...201728706312
endophthalmitis associated with purpureocillium lilacinum during infliximab treatment for surgically induced necrotizing scleritis, successfully treated with 27-gauge vitrectomy.to report a case of endophthalmitis associated with purpureocillium lilacinum (p. lilacinum) during infliximab treatment for surgically induced necrotizing scleritis, successfully treated with 27-gauge vitrectomy.201728429128
paecilomyces lilacinus septic olecranon bursitis in an immunocompetent host.paecilomyces lilacinus is a filamentous fungus that is a rare cause of infection in immunocompromised human hosts. we present a case of lilacinus septic olecranon bursitis in an otherwise healthy 78-year-old male. this patient's case was complicated by wound breakdown after bursectomy and appropriate anti-fungal treatment, requiring a local soft tissue rearrangement. this case demonstrates the need for appropriate and timely medical and surgical treatment in infections involving lilacinus, which ...201222715445
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