modulatory potentials of the aqueous stem bark extract of mangifera indica on carbon tetrachloride-induced hepatotoxicity in rats.among yoruba herbalists (southwest nigeria), hot water infusion of mangifera indica l. ( máng guǒ) stem bark is reputedly used for the treatment of fever, jaundice and liver disorders. the present study, therefore, investigates the protective effects and mechanism(s) of chemopreventive and curative effects of 125-500 mg/kg/day of mangifera indica aqueous stem bark extract (miase) in acute ccl4-induced liver damage in rats. rats were treated intragastrically with 125, 250 and 500 mg/kg/day of mia ...201526151020
enhancing antioxidant activity, microbial and sensory quality of mango (mangifera indica l.) juice by γ-irradiation and its in vitro radioprotective potential.gamma irradiation is an effective method currently being used for microbial decontamination and insect disinfestations of foods. in the present study, mango (mangifera indica l.) juice was irradiated at doses of 0, 1.0, 3.0 and 5.0 kgy and microbial load, total polyphenols, flavonoids, ascorbic acid content, antioxidant activities, colour and sensory properties were evaluated immediately after irradiation and also during storage. microbiological assay of the fresh and stored mango juice showed b ...201526139871
comparative assessment of phenolic content and in vitro antioxidant capacity in the pulp and peel of mango (mangifera indica l.), also called "the king of fruits", is one of the most popular fruits in tropical regions. pulp and peel samples of mango cultivars were analyzed to estimate total phenolic, total flavonoid and total anthocyanin contents. phenolic acids, hydrophilic peroxyl radical scavenging capacity (hydro-psc) and oxygen radical scavenging capacity (orac) in vitro were also determined. total phenolics and flavonoid contents were found maximum in the peel of xiao tainang and da taina ...201526075869
mangiferin ameliorates aluminium chloride-induced cognitive dysfunction via alleviation of hippocampal oxido-nitrosative stress, proinflammatory cytokines and acetylcholinesterase level.mangiferin is a phytochemical primarily present in the stem, leaves and bark of mangifera indica. it offers neuroprotection mainly through inhibition of oxidative stress, and decreasing proinflammatory cytokines level in the brain. aluminium has been reported to cause oxidative stress-associated damage in the brain. in the present investigation, protective effect of mangiferin against aluminium chloride (alcl3)-induced neurotoxicity and cognitive impairment was studied in male swiss albino mice. ...201526004900
wild edible plant species utilized by a subsistence farming community in obalanga sub-county, amuria district, uganda.farming communities have continuous interactions with their environment. subsistence farmers are particularly vulnerable to the vagaries of weather. these are pre-requisites for increased wild edible plant consumption. this study mainly focused on indigenous knowledge regarding identity and use of wild edible plant species by the subsistence farmers of obalanga.201525971428
evaluation of the fatty acid composition of the seeds of mangifera indica l. and their (mangifera indica l.), an edible fruit, is one of the main agricultural products in many tropical regions. mango varieties differ in not only fruit shape but also aroma, which is an important characteristic. although the fruit has many uses, the seeds are discarded as waste. therefore, this study aimed to estimate the fatty acid content of seed oil of mangoes from different cultivation areas (miyazaki, japan, and taiwan), and to evaluate their application in cosmetics. five fatty acids wer ...201525948136
estrogen modulation properties of mangiferin and quercetin and the mangiferin metabolite fruit contain many bioactive compounds, some of which are transcription factor regulators. estrogen receptor alpha (erα) and beta (erβ) are two regulators of gene transcription that are important in a variety of physiological processes and also in diseases including breast cancer. we examined the ability of the mango constituents quercetin, mangiferin, and the aglycone form of mangiferin, norathyriol, to activate both isoforms of the estrogen receptor. quercetin and norathyriol decreased t ...201525940566
comparative study of growth traits and haematological parameters of anak and nigerian heavy ecotype chickens fed with graded levels of mango seed kernel (mangifera indica) hundred fifty anak and 120 nigerian heavy local ecotype (nhle) chickens were used to study the effects of feeding graded levels of mango seed kernel meal (mkm) replacing maize diet on growth traits and haematological parameters. a 2 × 5 factorial arrangement was employed: two breeds and five diets. the birds were randomly allocated to five finisher diets formulated such that mkm replaced maize at 0, 10, 20, 30 and 40% (t1, t2, t3, t4 and t5) inclusion levels, respectively. the effect of bree ...201525939914
investigation of cream and ointment on antimicrobial activity of mangifera indica extract.medicinal plants have curative properties due to the presence of various complex chemical substance of different composition, which are found as secondary plant metabolites in one or more parts of these plants. mangifera indica linn (mi l.) is a species of mango in the anacardiaceae family. phytoconstituents in the seed extracts may be responsible for the antimicrobial activity of the plant. the purpose of the study was to formulate and evaluate the antimicrobial herbal ointment and cream from e ...201725878974
mango (mangifera indica l.) by-products and their valuable components: a review.the large amount of waste produced by the food industries causes serious environmental problems and also results in economic losses if not utilized effectively. different research reports have revealed that food industry by-products can be good sources of potentially valuable bioactive compounds. as such, the mango juice industry uses only the edible portions of the mangoes, and a considerable amount of peels and seeds are discarded as industrial waste. these mango by-products come from the trop ...201525863626
medicinal properties of mangiferin, structural features, derivative synthesis, pharmacokinetics and biological activities.the identification of biologically active and potentially therapeutically useful pharmacophores from natural products has been a long-term focus in the pharmaceutical industry. the recent emergence of a worldwide obesity and type ii diabetes epidemic has increased focus upon small molecules that can modulate energy metabolism, insulin sensitivity and fat biology. interesting preliminary work done on mangiferin (mgf), the predominant constituent of extracts of the mango plant mangifera indica l., ...201525827900
comparative study of the methane production based on the chemical compositions of mangifera indica and manihot utilissima leaves.leaves of mangifera indica (mi, mango leaves) and manihot utilissima (mu, cassava leaves) are available in tropical regions and are the most accessible vegetal wastes of kinshasa, capital of democratic republic of congo. these wastes are not suitably managed and are not rationally valorized. they are abandoned in full air, on the soil and in the rivers. they thus pollute environment. by contrast, they can be recuperated and treated in order to produce methane (energy source), organic fertilizer ...201525825684
atheromic and lymphoplasmacytic effects of mangifera indica methanolic leaf extract on the heart of chinchilla rabbits.the aim of this study was to evaluate the effect of methanol extract of mangifera indica on serum concentration of creatine kinase, total white blood cell (wbc) count and lymphocyte counts and the micro-anatomical architecture of the heart in chinchilla rabbits in order to find its safe and toxic levels. a total of 24 chinchilla rabbits aged 10-14 weeks, divided into four experimental groups were orally administered the doses of none, 500, 1000 and 1500 mg/kg body weight of the methanol extract ...201525803074
inhibition of secretary pla₂--vrv-pl-viiia of russell's viper venom by standard aqueous stem bark extract of mangifera indica l.the aqueous extract of mangifera indica is known to possess anti-snake venom activities. however, its inhibitory potency and mechanism of action on multi-toxic phospholipases a2s, which are the most toxic and lethal component of snake venom is still unknown. therefore, this study was carried out to evaluate the modulatory effect of standard aqueous bark extract of m. indica on vrv-pl-viiia of indian russells viper venom. mangifera indica extract dose dependently inhibited the giib spla2 (vrv-pl- ...201525801252
in vitro studies on mangiferin protection against cadmium-induced human renal endothelial damage and cell death via the map kinase and nf-κb pathways.the therapeutic effects of the natural antioxidant mangiferin (a xanthonoid and potent oxygen free radical scavenger), which is widely distributed in mango fruit, against cdcl(2)-induced toxicity in human renal glomerulus endothelial cells (hrgec) were investigated. the viability of hregcs that were treated with cdcl(2) (25 µ mol) and co-treated with mangiferin (75 µ mol) for 24 h was measured by crystal violet dye. the exposure of human glomerulus renal endothelial cells to cadmium promotes a p ...201625798666
[in vitro and in vivo effects of mango pulp (mangifera indica cv. azucar) in colon carcinogenesis].mango pulp contains ascorbic acid, carotenoids, polyphenols, terpenoids and fiber which are healthy and could protect against colon cancer. the aim of this study was to evaluate the antiproliferative and preventive capacity of an aqueous extract of mangifera indica cv. azúcar on a human colon adenocarcinoma cell line (sw480) and in a rodent model of colorectal cancer, respectively. the content of total phenolics, flavonoids and carotenoids were also analyzed in the extract. sw480 cell growth was ...201425796713
mango (mangifera indica l.) cv. kent fruit mesocarp de novo transcriptome assembly identifies gene families important for ripening.fruit ripening is a physiological and biochemical process genetically programmed to regulate fruit quality parameters like firmness, flavor, odor and color, as well as production of ethylene in climacteric fruit. in this study, a transcriptomic analysis of mango (mangifera indica l.) mesocarp cv. "kent" was done to identify key genes associated with fruit ripening. using the illumina sequencing platform, 67,682,269 clean reads were obtained and a transcriptome of 4.8 gb. a total of 33,142 coding ...201525741352
phytochemical and in vitro and in vivo biological investigation on the antihypertensive activity of mango leaves (mangifera indica l.).the aim of this study was to investigate the antihypertensive effect of leaves mangifera indica l. using in vitro and in vivo assays.201525724882
physico chemical characterization and the effect of processing on the quality characteristics of sindura, mallika and totapuri mango (magnifera indica l) is grown in the tropical and sub tropical regions of india. the fruit has a high commercial value depending on the color, flavor and pulp characteristics of the cultivar. sindura, mallika and totapuri cultivars grown in southern karnataka were investigated for the physical chemical characteristics and the effect of processing on the quality characteristics. sindura, mallika and totapuri mango cultivars had significantly different physico chemical and compositional char ...201525694717
residue levels and dissipation behaviors for trifloxystrobin and tebuconazole in mango fruit and evaluation of residue levels of trifloxystrobin and tebuconazole was carried out on mango fruits after treatments with the combined formulation, trifloxystrobin (25 % w/w) and tebuconazole (50 % w/w), at standard and double doses of 250 + 500 and 500 + 1000 g a.i. ha(-1), respectively. extraction and purification of the mango fruit samples were carried out by the quechers method after validating the analytical parameters. determination of the fungicides was carried out by gas chromatography ( ...201525663402
mangiferin ameliorates the intestinal inflammatory response and the impaired gastrointestinal motility in mouse model of postoperative ileus.our previous study has shown that mangiferin (mgf), a glucosylxanthone from mangifera indica, exerts gastrointestinal prokinetic action involving a cholinergic mechanism. postoperative ileus (poi) is a temporary disturbance in gastrointestinal motility following surgery, and intestinal inflammatory response plays a critical role in the pathogenesis of poi. the present study investigated to know whether mgf having anti-inflammatory and prokinetic actions can ameliorate the intestinal inflammation ...201525653124
uni-dimensional double development hptlc-densitometry method for simultaneous analysis of mangiferin and lupeol content in mango (mangifera indica) pulp and peel during (mangifera indica) fruit is one of the important commercial fruit crops of india. similar to other tropical fruits it is also highly perishable in nature. during storage/ripening, changes in its physico-chemical quality parameters viz. firmness, titrable acidity, total soluble solid content (tssc), carotenoids content, and other biochemicals are inevitable. a uni-dimensional double-development high-performance thin-layer chromatography (uddd-hptlc) method was developed for the real-time mo ...201525624210
bioaccessibility of polyphenols associated with dietary fiber and in vitro kinetics release of polyphenols in mexican 'ataulfo' mango (mangifera indica l.) by-products.the biological properties of polyphenol (pp) depend on its bioaccessibility and bioavailability. therefore, part of pp released from the food matrix in the gastrointestinal tract through enzymatic hydrolysis is at least partially absorbed. the aim of this study is to determine the bioaccessibility of pp associated with dietary fiber (df) and the kinetics release of pp in mango (mangifera indica l.) 'ataulfo' by-products by an in vitro model. soluble and insoluble df values were 7.99 and 18.56% i ...201525608953
influence of different desapping agents on the incidence of sapburn, ripening behaviour and quality of mango.sapburn injury in mango is regarded as the most serious problem as it reduces the aesthetic appeal and downgrade the fruit quality with considerable economic losses. for the control of sapburn injury, physiologically mature mango fruits of cv. chausa were harvested along with 5-8 cm stalk attached. immediately after harvesting, fruits were de-stemmed and treated with different desapping agent solutions [calcium hydroxide (1 %), sodium hydroxide (1 %), alum (0.5 and 1 %)] by dipping them for 5 mi ...201525593366
utilization of physicochemical variables developed from changes in sensory attributes and consumer acceptability to predict the shelf life of fresh-cut mango fruit.sensory evaluation is the ideal tool for shelf-life determination. with the objective to develop an easy shelf-life indicator, color (l*, a*, b*, chroma and hue angle), total soluble solids (tss), firmness (f), ph, acidity, and the sensory attributes of appearance, brightness, browning, odor, flavor, texture, color, acidity and sweetness were evaluated in fresh cut mangoes (fcm) stored at 5, 10, 15 and 20 °c. overall acceptability was evaluated by consumers. correlation analysis between sensory ...201525593365
modulation of diabetes and dyslipidemia in diabetic insulin-resistant rats by mangiferin: role of adiponectin and tnf-α.mangiferin, present in mangifera indica bark, was reported to produce hypoglycemic and antidiabetic activity in an animal model of genetic type 2 diabetes and in streptozotocin diabetic rats. its effect on diabetic insulin-resistant animals has not been investigated. the current work aimed to explore the effect of mangiferin on diabetic insulin-resistant rat model. diabetes was induced by high-fat/high fructose diet for eight weeks followed by a subdiabetogenic dose of streptozotocin (hfd-fr-stz ...201425590730
simultaneous ultrasound-assisted water extraction and β-cyclodextrin encapsulation of polyphenols from mangifera indica stem bark in counteracting tnfα-induced endothelial dysfunction.this study proposes an alternative technique to prevent heat degradation induced by classic procedures of bioactive compound extraction, comparing classical maceration/decoction in hot water of polyphenols from mango (mangifera indica l.) (mi) with ultrasound-assisted extraction (uae) in a water solution of β-cyclodextrin (β-cd) at room temperature and testing their biological activity on tnfα-induced endothelial dysfunction. both extracts counteracted tnfα effects on eahy926 cells, down-modulat ...201525589236
antidiarrhoeal activity of aqueous extract of mangifera indica l. leaves in female albino rats.mangifera indica l. leaves have a long history of indigenous use, as an antidiarrhoeal agent among others, without any scientific study that has substantiated or refuted this claim. therefore, the aims of this study were to determine the secondary metabolites in the aqueous extract of mangifera indica leaves and its acclaimed antidiarrhoeal activity in rats.201525575467
[mango: agroindustrial aspects, nutritional/functional value and health effects].to review and discuss the latest information on agroindustrial, functional and nutritional value of one of the most produced/consumed fruit crop in méxico: the mango.201425561099
identification of new phytoconstituents and antimicrobial activity in stem bark of mangifera indica (l.).mangifera indica, commonly called mango or amra belonging to a family of anacardiaceae, is an important medicinal plant widely used in a variety of ayurvedic preparations. extract of its bark, leaves, flowers and kernels are being extensively used for curing various chronic diseases. mango wood is used in yagya as base fire through which medicated smoke is generated. three new compounds have been isolated from methanolic and hexane extracts of stem bark: 1,2-benzenedicarboxylic acid, mono(2-ethy ...201525555263
dna analysis of soil extracts can be used to investigate fine root depth distribution of trees.understanding the root distribution of trees by soil coring is time -: consuming as it requires the separation of roots from soil and classification of roots into particular size classes. this labour-intensive process can limit sample throughput and therefore sampling intensity. we investigated the use of quantitative polymerase chain reaction (qpcr) on soil dna extractions to determine live fine root dna density (rdd, mg dna m(-2)) for mango (mangifera indica) trees. the specificity of the qpcr ...201425552675
a novel method to augment extraction of mangiferin by application of microwave on three phase partitioning.this work reports a novel approach where three phase partitioning (tpp) was combined with microwave for extraction of mangiferin from leaves of mangifera indica. soxhlet extraction was used as reference method, which yielded 57 mg/g in 5 h. under optimal conditions such as microwave irradiation time 5 min, ammonium sulphate concentration 40% w/v, power 272 w, solute to solvent ratio 1:20, slurry to t-butanol ratio 1:1, soaking time 5 min and duty cycle 50%, the mangiferin yield obtained was 54 m ...201528626691
novel strategies for capturing health-protective mango phytochemicals in shelf stable food matrices.cost-effective methods for concentration and stabilization of otherwise perishable mango fruit phytoactives into shelf stable high protein ingredients were developed to combat stunting (malnutrition) in rural africa. mango juices complexed with sunflower oil and protein-rich legume flours yielded carotenoid-enriched oils and pelleted polyphenol-enriched flour matrices. carotenoids from juices were concentrated 9-10 times in the fortified sunflower oil. protein-rich soy and peanut flours captured ...201525519247
anti-inflammatory effects of aqueous extract of mangifera indica in wistar rats.recent studies in standard laboratories have indicated that a typical mango stem bark aqueous extract (magnifera indica linn) possess anti-malaria and anti-fever properties. recent information also exists in the literature, suggesting its potency as a very effective anti-inflammatory plant extract. this study will therefore contribute immensely to the systemic search for a useful, less toxic and natural bioactive medicinal compound.201525473801
analysing growth and development of plants jointly using developmental growth stages.plant growth, the increase of organ dimensions over time, and development, the change in plant structure, are often studied as two separate processes. however, there is structural and functional evidence that these two processes are strongly related. the aim of this study was to investigate the co-ordination between growth and development using mango trees, which have well-defined developmental stages.201525452250
the effects of mangiferin (mangifera indica l) in doxorubicin-induced cardiotoxicity in rats.the cardiotoxicity effect of doxorubicin (dox), a widely used antitumor agent has restricted its clinical application. the aim of the current study was to explore the potential protective effect of mangiferin, a naturally occurring glucosylxanthone, that have antioxidant activity by its iron-complexing ability in mitochondria, against dox-induced cardiac toxicity in rats in comparison with other antioxidants namely sylimarin (syl) and vitamin e (vite).201525426848
degradation pattern and risk assessment of carbendazim and mancozeb in mango fruits.a supervised field trial was conducted at four different agroclimatic locations in india to evaluate the dissipation pattern and risk assessment of carbendazim and mancozeb in mango fruits following foliar application of mixed formulation of carbendazim 12% and mancozeb 63% fungicide (saaf-75wp) at recommended dose (90 + 472.5) and double the recommended dose (180 + 945 g a.i. ha(-1)). average initial deposition of carbendazim was in the range of 1.12 to 2.7 and 1.95 to 4.09 mg kg(-1) and for ma ...201525407993
fluorescent carbon nanoparticles derived from natural materials of mango fruit for bio-imaging probes.water soluble fluorescent carbon nanoparticles (fcp) obtained from a single natural source, mango fruit, were developed as unique materials for non-toxic bio-imaging with different colors and particle sizes. the prepared fcps showed blue (fcp-b), green (fcp-g) and yellow (fcp-y) fluorescence, derived by the controlled carbonization method. the fcps demonstrated hydrodynamic diameters of 5-15 nm, holding great promise for clinical applications. the biocompatible fcps demonstrated great potential ...201425375199
de-novo assembly of mango fruit peel transcriptome reveals mechanisms of mango response to hot water treatment.the mango belongs to the genus mangifera, consisting of numerous tropical fruiting trees in the flowering plant family, anacardiaceae. postharvest treatment by hot water brushing (hwb) for 15-20 s was introduced commercially to improve fruit quality and reduce postharvest disease. this treatment enabled successful storage for 3-4 weeks at 12°c, with improved color and reduced disease development, but it enhanced lenticel discoloration on the fruit peel. we investigated global gene expression ind ...201425373421
cholesterol esterase inhibitory activity of bioactives from leaves of mangifera indica the earlier studies, methanolic extract of mangifera indica l leaf was exhibited hypocholesterol activity. however, the bioactive compounds responsible for the same are not reported so far.201726692750
uv-b irradiation alleviates the deterioration of cold-stored mangoes by enhancing endogenous nitric oxide levels.effects of uv-b radiation on chilling injury, ripening and endogenous nitric oxide (no) levels in mango fruit were evaluated. chilling injury index, ion leakage, and malondialdehyde (mda) content of the fruit pretreated with 5kjm(-2) uv-b for 4h were significantly lower than those of the control during fruit ripening at ambient temperature following cold storage at 6°c for 10days. fruit firmness of the mangoes irradiated with uv-b was significantly higher than the control during the ripening per ...201525236246
development and validation of an hplc method for the determination of alk(en)ylresorcinols using rapid ultrasound-assisted extraction of mango peels and rye grains.exhaustive extraction of alk(en)ylresorcinols (ars) from biological matrices is a prerequisite for economic screening of extensive plant collections including their rapid quantitation. for this purpose, an ultrasound-assisted extraction protocol was developed to facilitate the liberation of ars from mango peels (mangifera indica l.) and rye grains (secale cereale l.). while maintaining or even improving the extraction efficiency of the analytes, the duration of analytical extraction was shortene ...201525236225
purification and partial biochemical characterization of polyphenol oxidase from mango (mangifera indica cv. manila).polyphenol oxidase (ppo) is an enzyme widely distributed in the plant kingdom that has been detected in most fruits and vegetables. ppo was extracted and purified from manila mango (mangifera indica), and its biochemical properties were studied. ppo was purified 216-fold by hydrophobic interaction and ion exchange chromatography. ppo was purified to homogeneity, and the estimated ppo molecular weight (mw) by sds-page was ≈31.5 kda. however, a mw of 65 kda was determined by gel filtration, indica ...201425211397
mango supplementation improves blood glucose in obese individuals.this pilot study examined the effects of freeze-dried mango (mangifera indica l.) supplementation on anthropometrics, body composition, and biochemical parameters in obese individuals. twenty obese adults (11 males and 9 females) ages 20- to 50-years old, received 10 g/day of ground freeze-dried mango pulp for 12 weeks. anthropometrics, biochemical parameters, and body composition were assessed at baseline and final visits of the study. after 12 weeks, mango supplementation significantly reduced ...201425210462
phytochemical composition and effects of commercial enzymes on the hydrolysis of gallic acid glycosides in mango (mangifera indica l. cv. 'keitt') pulp.a detailed characterization of mango pulp polyphenols and other minor phytochemicals was accomplished for the first time in the cultivar 'keitt' whereby the identification and semiquantification of five hydroxybenzoic acids, four cinnamic acids, two flavonoids, and six apocarotenoids was accomplished. among the most abundant compounds were two monogalloyl glucosides (mgg) identified as having an ester- or ether-linked glucose, with the ester-linked moiety present in the highest concentration amo ...201425185991
physiologic and metabolic benefits of formulated diets and mangifera indica in fluoride toxicity.fluorosis is a major health problem affecting normal physiological and metabolic functions in people living in endemic fluoride areas. the present work was aimed at investigating the role of basal, high carbohydrate low protein (hclp) and high protein low carbohydrate (hplc) diets and mangifera indica fruit powder as a food supplement in fluoride-induced metabolic toxicity. exposure to fluoride resulted in elevation of plasma glucose levels, acp, alp, sgpt, sgot, and hepatic g-6-pase activities, ...201525166890
spatial and temporal variations in mango colour, acidity, and sweetness in relation to temperature and ethylene gradients within the fruit.managing fruit quality is complex because many different attributes have to be taken into account, which are themselves subjected to spatial and temporal variations. heterogeneous fruit quality has been assumed to be partly related to temperature and maturity gradients within the fruit. to test this assumption, we measured the spatial variability of certain mango fruit quality traits: colour of the peel and of the flesh, and sourness and sweetness, at different stages of fruit maturity using des ...201425151123
chemical composition, leishmanicidal and cytotoxic activities of the essential oils from mangifera indica l. var. rosa and espada.the essential oils from mangifera indica var. rosa and espada latex were obtained by hydrodistillation and analyzed using gc-fid and gc-ms. twenty-seven components were identified. the main compound in the essential oil from m. indica var. espada (eomie) was terpinolene (73.6%). the essential oil of m. indica var. rosa (eomir) was characterized by high amounts of β-pinene (40.7%) and terpinolene (28.3%). in the test for leishmanicidal activity against promastigotes forms of l. amazonensis, eomir ...201425136617
changes in biochemical characteristics and activities of ripening associated enzymes in mango fruit during the storage at different a part of the study to explore the possible strategy for enhancing the shelf life of mango fruits, we investigated the changes in biochemical parameters and activities of ripening associated enzymes of ashwina hybrid mangoes at 4-day regular intervals during storage at -10°c, 4°c, and 30 ± 1°c. titratable acidity, vitamin c, starch content, and reducing sugar were higher at unripe state and gradually decreased with the increasing of storage time at all storage temperatures while phenol conten ...201425136564
characterization and storage stability of the extract of thai mango (mangifera indica linn. cultivar chok-anan) seed kernels.qualitative analysis of hydrolysable extract from mango (mangifera indica linn. cultivar chok-anan) seed kernel was performed by means of reversed phase high-performance liquid chromatography coupled to diode array detection and electrospray ionization mass spectrometry (rphplc-dad-esi-ms). the main phenolic compound was identified as methyl gallate by comparing their retention time, uv-vis absorption spectra and mass spectra with a reference standard. quantification of phenolic compounds was pe ...201425114335
protective effect of mangiferin against lipopolysaccharide-induced depressive and anxiety-like behaviour in mice.numerous studies have demonstrated that inflammation, oxidative stress and altered level of neurotrophins are involved in the pathogenesis of depressive illness. mangiferin, a c-glucosylxanthone is abundant in the stem and bark of mangifera indica l. the compound has been shown to possess antioxidant, anti-inflammatory and immunomodulatory activities. the present study was performed to investigate the effect of mangiferin pretreatment on lipopolysaccharide-induced increased proinflammatory cytok ...201425064341
oligo-dt anchored cdna-scot: a novel differential display method for analyzing differential gene expression in response to several stress treatments in mango (mangifera indica l.).differential display is a powerful technique for analyzing differences in gene expression. oligo-dt cdnastart codon targeted marker (cdna-scot) technique is a novel, simple, cheap, rapid, and efficient method for differential gene expression research. in the present study, the oligo-dt anchored cdna-scot technique was exploited to identify differentially expressed genes during several stress treatments in mango. a total of 37 primers combined with oligo-dt anchor primers 3side amplified approxim ...201425017057
postharvest vapour heat treatment as a phytosanitary measure influences the aroma volatiles profile of mango fruit.our objective was to determine the influence of postharvest vapour heat treatment (vht) on qualitative and quantitative measurement of aroma volatiles during fruit ripening in mango (cv. chausa) using gas chromatography-mass spectrometry (gc-ms). vht (48°c for 20 min) accelerated the process of fruit ripening leading to edible-soft stage within 4 days after heat treatment against 8 days in control. reversible inhibition of aroma volatiles emission was observed in heat-treated fruit, with a signi ...201424996349
mangiferin ameliorates colitis by inhibiting irak1 phosphorylation in nf-κb and mapk pathways.mangiferin, a main constituent of the root of anemarrhena asphodeloides and the leaves of mangifera indica, inhibits nf-κb activation in macrophages. therefore, we investigated effect of mangiferin on 2,3,4-trinitrobenzene sulfonic acid (tnbs)-induced colitis in mice and its anti-inflammatory mechanism in lipolysaccharide (lps)- or peptidoglycan-stimulated mouse peritoneal macrophages. mangiferin inhibited phosphorylation of nuclear factor-kappab (nf-κb), interleukin-1 receptor-associated kinase ...201424972244
diapause incidence and duration in the pest mango blossom gall midge, procontarinia mangiferae (felt), on reunion island.the mango blossom gall midge, procontarinia mangiferae, is a multivoltine species that induces galls in inflorescences and leaves of the mango tree, mangifera indica. in subtropical reunion island, populations of p. mangiferae are observed all-year round, but the pattern and the role of dormancy in their life cycle have never been documented. we performed field and laboratory experiments using more than 15,000 larvae. we demonstrated that a larval diapause may affect a part of the midge populati ...201424963639
cytotoxic effects of mangifera indica l. kernel extract on human breast cancer (mcf-7 and mda-mb-231 cell lines) and bioactive constituents in the crude extract.waterlily mango (mangifera indica l.) is thought to be antioxidant-rich, conferred by its functional phytochemicals.201424962691
mangiferin attenuates th1/th2 cytokine imbalance in an ovalbumin-induced asthmatic mouse model.mangiferin is a major bioactive ingredient in mangifera indica linn. (anacardiaceae) leaves. aqueous extract of such leaves have been used as an indigenous remedy for respiratory diseases like asthma and coughing in traditional chinese medicine. however, underlying molecular mechanisms of mangiferin on anti-asthma remain unclear. in our present study, we investigated the anti-asthmatic effect of mangiferin on th1/th2 cytokine profiles and explored its underlying immunoregulatory mechanism in mou ...201424955743
expression and enzymatic activity of phenylalanine ammonia-lyase and p-coumarate 3-hydroxylase in mango (mangifera indica 'ataulfo') during ripening.phenylalanine ammonia lyase (pal) and p-coumarate 3-hydroxylase (c3h) are key enzymes in the phenylpropanoid pathway. the relative expression of pal and c3h was evaluated in mango fruit cultivar 'ataulfo' in four ripening stages (rs1, rs2, rs3, and rs4) by quantitative polymerase chain reaction. in addition, enzyme activity of pal and c3h was determined in mango fruits during ripening. the pal levels were downregulated at the rs2 and rs3 stages, while c3h levels were upregulated in fruits only a ...201424938473
enhancing safety and shelf life of fresh-cut mango by application of edible coatings and microencapsulation pulp is very perishable and so has a short shelf life, which both marketers and consumers would like to be longer. manually sliced mango was treated by coating opuntia mucilage-rosemary oil (mu + ro), 2 g rosemary oil microencapsul (rom), and 2 g (rom) plus (mu + ro); the treated mango pieces were placed in plastic trays, and overwrapped with pvdc film and then stored at 6°c. changes in the quality parameters and activity of peroxidase (pod) enzyme were evaluated for 9 days of storage peri ...201424936290
anti-diabetic effect of dietary mango (mangifera indica l.) peel in streptozotocin-induced diabetic the present study, the composition of mango peel powder (mpp) collected from the mango pulp industry was determined and the effect of mpp on ameliorating diabetes and its associated complications was studied.201524917522
effects of sonication and ultraviolet-c treatment as a hurdle concept on quality attributes of chokanan mango (mangifera indica l.) juice.the growing demand for fresh-like food products has encouraged the development of hurdle technology of non-thermal processing. in this study, freshly squeezed chokanan mango juice was treated by paired combinations of sonication (for 15 and 30 min at 25 ℃, 40 khz frequency) and uv-c treatment (for 15 and 30 min at 25 ℃). selected physicochemical properties, antioxidant activities, microbial inactivation and other quality parameters of combined treated juice were compared to conventional thermal ...201524854293
antihyperalgesic effects of an aqueous stem bark extract of mangifera indica l.: role of mangiferin isolated from the extract.this study aimed to assess the effects of a mangifera indica stem bark extract (msbe) and mangiferin (mg) on pain-related acute behaviors in the formalin 5% test. rats received repeated oral msbe (125-500 mg/kg) once daily for 7 days before formalin injection. other four groups with the same treatments were performed in order to study the effect of msbe on the formalin-induced long-term secondary mechano-hyperalgesia at 7 days after the injury by means of the pin-prick method. additional groups ...201424849742
mangiferin stimulates carbohydrate oxidation and protects against metabolic disorders induced by high-fat diets.excessive dietary fat intake causes systemic metabolic toxicity, manifested in weight gain, hyperglycemia, and insulin resistance. in addition, carbohydrate utilization as a fuel is substantially inhibited. correction or reversal of these effects during high-fat diet (hfd) intake is of exceptional interest in light of widespread occurrence of diet-associated metabolic disorders in global human populations. here we report that mangiferin (mgf), a natural compound (the predominant constituent of m ...201424848064
assessment of genetic diversity and relationships among egyptian mango (mangifera indica l.) cultivers grown in suez canal and sinai region using rapd markers.dna-based rapd (random amplification of polymorphic dna) markers have been used extensively to study genetic diversity and relationships in a number of fruit crops. in this study, 10 (7 commercial mango cultivars and 3 accessions) mango genotypes traditionally grown in suez canal and sinai region of egypt, were selected to assess genetic diversity and relatedness. total genomic dna was extracted and subjected to rapd analysis using 30 arbitrary 10-mer primers. of these, eleven primers were selec ...201424783778
evaluation of extraction methods for preparative scale obtention of mangiferin and lupeol from mango peels (mangifera indica l.).bioactive compounds have become very important in the food and pharmaceutical markets leading research interests seeking efficient methods for extracting these bioactive substances. the objective of this research is to implement preparative scale obtention of mangiferin and lupeol from mango fruit (mangifera indica l.) of autochthonous and ataulfo varieties grown in nayarit, using emerging extraction techniques. five extraction techniques were evaluated: maceration, soxhlet, sonication (uae), mi ...201424767054
characterization of the major aroma-active compounds in mango (mangifera indica l.) cultivars haden, white alfonso, praya sowoy, royal special, and malindi by application of a comparative aroma extract dilution analysis.the aroma-active compounds present in tree-ripened fruits of the five mango (mangifera indica l.) cultivars haden, white alfonso, praya sowoy, royal special, and malindi were isolated by solvent extraction followed by solvent-assisted flavor evaporation (safe) and analyzed by gas chromatography-olfactometery (gc-o). application of a comparative aroma extract dilution analysis (caeda) afforded 54 aroma-active compounds in the flavor dilution (fd) factor range from 4 to ≥2048, 16 of which are repo ...201424766361
transcriptome and proteomic analysis of mango (mangifera indica linn) we used illumina rna-seq technology for transcriptome sequencing of a mixed fruit sample from 'zill' mango (mangifera indica linn) fruit pericarp and pulp during the development and ripening stages. rna-seq generated 68,419,722 sequence reads that were assembled into 54,207 transcripts with a mean length of 858bp, including 26,413 clusters and 27,794 singletons. a total of 42,515(78.43%) transcripts were annotated using public protein databases, with a cut-off e-value above 10(-5), of which ...201424704857
a quantitative documentation of the composition of two powdered herbal formulations (antimalarial and haematinic) using ethnomedicinal information from ogbomoso, nigeria.the safety of many african traditional herbal remedies is doubtful due to lack of standardization. this study therefore attempted to standardize two polyherbal formulations from ogbomoso, oyo state, nigeria, with respect to the relative proportions (weight-for-weight) of their botanical constituents. information supplied by 41 local herbal practitioners was statistically screened for consistency and then used to quantify the composition of antimalarial (maloff-hb) and haematinic (haematol-b) pow ...201424701246
effectiveness of calcium chloride and calcium lactate on maintenance of textural and sensory qualities of fresh-cut mangos.the effects of calcium chloride (cacl2 ) and calcium lactate on maintaining textural and sensory quality of fresh-cut "kent" and "tommy atkins" mangos and determination of treatments preferred by consumers were investigated. mango cubes (1.5 × 1.5 × 1.5 cm) were subjected to different cacl2 and calcium lactate concentrations (0 m, 0.068 m, 0.136 m, 0.204 m) and dip times (0, 1, 2.5, 5 min). instrumental quality parameters (firmness, color, soluble solids, titratable acidity) were analyzed period ...201424697776
lactic acid fermentation by cells immobilised on various porous cellulosic materials and their alginate/poly-lactic acid composites.porous delignified cellulose (or tubular cellulose, abbr. tc) from indian mango (mangifera indica) and sal (shorea robusta) wood and rice husk, and tc/ca-alginate/polylactic acid composites, were used as lactobacillus bulgaricus immobilisation carriers leading to improvements in lactic acid fermentation of cheese whey and synthetic lactose media, compared to free cells. specifically, shorter fermentation rates, higher lactic acid yields (g/g sugar utilised) and productivities (g/ld), and higher ...201424690466
mangifera indica fruit extract improves memory impairment, cholinergic dysfunction, and oxidative stress damage in animal model of mild cognitive date, the effective preventive paradigm against mild cognitive impairment (mci) is required. therefore, we aimed to determine whether mangifera indica fruit extract, a substance possessing antioxidant and cognitive enhancing effects, could improve memory impairment, cholinergic dysfunction, and oxidative stress damage in animal model of mild cognitive impairment. male wistar rats, weighing 180-200 g, were orally given the extract at doses of 12.5, 50, and 200 mg · kg(-1) bw for 2 weeks before ...201424672632
model-assisted analysis of spatial and temporal variations in fruit temperature and transpiration highlighting the role of fruit development.fruit physiology is strongly affected by both fruit temperature and water losses through transpiration. fruit temperature and its transpiration vary with environmental factors and fruit characteristics. in line with previous studies, measurements of physical and thermal fruit properties were found to significantly vary between fruit tissues and maturity stages. to study the impact of these variations on fruit temperature and transpiration, a modelling approach was used. a physical model was deve ...201424663687
biochemical changes in some deciduous tree species around talcher thermal power station, odisha, india.the present study was conducted to evaluate biochemical traits in leaves to assess the air pollution impact on plants caused by thermal power plant emissions. ten species of deciduous trees were selected from study sites in different seasons. ph, chlorophyll, phenols, total soluble sugar content and proline content in fresh leaf was analyzed. the leaf wash ph content reveals moderately acidic (4.5-5.0) to highly acidic (3.5-4.5) range. significant differences (p < 0.01) were observed in chloroph ...201324617137
dual mode action of mangiferin in mouse liver under high fat diet.chronic over-nutrition is a major contributor to the spread of obesity and its related metabolic disorders. development of therapeutics has been slow compared to the speedy increase in occurrence of these metabolic disorders. we have identified a natural compound, mangiferin (mgf) (a predominant component of the plants of anemarrhena asphodeloides and mangifera indica), that can protect against high fat diet (hfd) induced obesity, hyperglycemia, insulin resistance and hyperlipidemia in mice. how ...201424598864
effects of 1-methylcyclopropene and hot water quarantine treatment on quality of "keitt" mangos.the optimal 1-methylcyclopropene (1-mcp) treatment to slow ripening of whole "keitt" mangos, either alone or in combination with hot water treatment (hwt) (prior to or post 1-mcp) was identified. usda-aphis mandates that hwt can be used for control of fruit flies, but this may affect fruit response to 1-mcp. mangos were evaluated by repeated measurement of nondestructive firmness, peel color, and ethylene production on the same mango fruits during 2 wk of ripening at 20 °c after treatment. the m ...201424592887
molecular characterization and expression analysis of a gtp-binding protein (mirab5) in mangifera indica.the rab family, the largest branch of ras small gtpases, plays a crucial role in the vesicular transport in plants. the members of rab family act as molecular switches that regulate the fusion of vesicles with target membranes through conformational changes. however, little is known about the rab5 gene involved in fruit ripening and stress response. in this study, the mirab5 gene was isolated from stress-induced mangifera indica. the full-length cdna sequence was 984bp and contained an open read ...201424560931
behavioral pattern of physicochemical constituents of the postharvest mango (mangifera indica l.) influenced by storage investigation was carried at the laboratory of the department of biochemistry and molecular biology, university of rajshahi, bangladesh during the period from may, 2010 to september, 2011 to study the behavioral pattern of some physicochemical constituents of the mango pulp. the experiment was comprised of two popular mango cultivars in bangladesh (viz., langra and khirshapat) and six storage stimuli, namely control, paraffin coating, perforated polyethylene cover, unperforated polyethylene c ...201324517016
ultrasound-assisted extraction of mangiferin from mango (mangifera indica l.) leaves using response surface methodology.mangiferin is a xanthone widely distributed in higher plants showing antioxidative, antiviral, anticancer, antidiabetic, immunomodulatory, hepatoprotective and analgesic effects. in the present study, an ultrasonic-assisted extraction method was developed for the effective extraction of mangiferin from mango leaves. some parameters such as ethanol concentration, liquid-to-solid ratio, extraction temperature, and extraction time were optimized by single-factor experiment and response surface meth ...201424473205
antioxidant properties and hyphenated hplc-pda-ms profiling of chilean pica mango fruits (mangifera indica l. cv. piqueño).antioxidant capacities and polyphenolic contents of two mango cultivars from northern chile, one of them endemic of an oasis in the atacama desert, were compared for the first time. twenty one phenolic compounds were detected in peel and pulp of mango fruits varieties pica and tommy atkins by hplc-pda-ms and tentatively characterized. eighteen compounds were present in pica pulp (ppu), 13 in pica peel (ppe) 11 in tommy atkins pulp (tpu) and 12 in tommy atkins peel (tpe). three procyanidin dimers ...201324384924
hepatoprotective and antioxidant effect of mangifera indica leaf extracts against mercuric chloride-induced liver toxicity in explore the antioxidant and hepatoprotective effect of ethanolic mangifera indica (emi) and methanolic mangifera indica (mmi) leaf extracts in mercuric chloride (hgcl2) induced toxicity in swiss albino mice.201729264314
molecular modeling and expression analysis of a mads-box cdna from mango (mangifera indica l.).mads-box genes are a large family of transcription factors initially discovered for their role during development of flowers and fruits. the mads-box transcription factors from animals have been studied by x-ray protein crystallography but those from plants remain to be studied. in this work, a mads-box cdna from mango encoding a protein of 254 residues was obtained and compared. based on phylogenetic analysis, it is proposed that the mads-box transcription factor expressed in mango fruit (mimad ...201428324472
fda-approved natural polymers for fast dissolving tablets.oral route is the most preferred route for administration of different drugs because it is regarded as safest, most convenient, and economical route. fast disintegrating tablets are very popular nowadays as they get dissolved or facilely disintegrated in mouth within few seconds of administration without the need of water. the disadvantages of conventional dosage form, especially dysphagia (arduousness in swallowing), in pediatric and geriatric patients have been overcome by fast dissolving tabl ...201426556207
occurrence of alk(en)ylresorcinols in the fruits of two mango (mangifera indica l.) cultivars during on-tree maturation and postharvest storage.regarding their relevance for the fungal resistance of mangoes in long supply chains, the alk(en)ylresorcinols (ar) were quantitated in peel and mesocarp throughout storage (27 days, 14 °c, ethylene absorption). the 12 'chok anan' and 11 'nam dokmai #4' lots picked between 83 and 115 days after full bloom (dafb) had different harvest maturity indices. the development of dry matter and fruit growth indicated physiological maturity ∼100 dafb. during storage, all fruits ripened slowly, mostly until ...201424350757
combination of mangifera indica l. extract supplementation plus methotrexate in rheumatoid arthritis patients: a pilot study.the purpose of the present study was to evaluate the possible therapeutic effects and the safety of mangifera indica extract (vimang tablets, 300 mg) combined with methotrexate (mtx) on reducing disease activity in rheumatoid arthritis (ra). twenty patients with active ra underwent a year of treatment with mtx (12.5 mg/week) associated to non-steroidal anti-inflammatory drugs (nsaids) and/or prednisone (5-10 mg/day) were randomly allocated to the experimental group (n=10), that received the extr ...201424344049
phytochemical extraction, characterisation and comparative distribution across four mango (mangifera indica l.) fruit this study we determined the qualitative composition and distribution of phytochemicals in peel and flesh of fruits from four different varieties of mango using mass spectrometry profiling following fractionation of methanol extracts by preparative hplc. gallic acid substituted compounds, of diverse core structure, were characteristic of the phytochemicals extracted using this approach. other principal compounds identified were from the quercetin family, the hydrolysable tannins and fatty aci ...201424295704
effects of modified atmosphere packaging on quality of 'alphonso' mangoes.postharvest quality of alphonso mangoes (mangifera indica l) is vital to ensure proper ripening and good quality. 500 g mature green mangoes, were subjected to three pre- packaging hot water dips (20, 30 & 40°c) for 40 min, two packaging films (opp unperforated and perforated), using three levels of gas concentrations of 25,50 and 75% v/v co2 treatments (balance n2) and stored at 10°c for 21 days. during the storage period headspace gas composition, weight loss, ascorbic acid, pulp firmness, ext ...201224293691
plant ionome diagnosis using sound balances: case study with mango (mangifera indica).plant ionomes and soil nutrients are commonly diagnosed in agronomy using concentration and nutrient ratio ranges. however, both diagnoses are biased by redundancy of information, subcompositional incoherence and non-normal distribution inherent to compositional data, potentially leading to conflicting results and wrong inferences. our objective was to present an unbiased statistical approach of plant nutrient diagnosis using a balance concept and mango (mangifera indica) as test crop. we collec ...201324273548
effects of a mangifera indica l. stem bark extract and mangiferin on radiation-induced dna damage in human lymphocytes and lymphoblastoid cells.mangifera indica l. (mango) stem bark aqueous extract (msbe) that has antioxidant, anti-inflammatory and immunomodulatory properties, can be obtained in cuba. it is rich in polyphenols, where mangiferin is the main component. in this study, we have tested dna damage and protection effects of msbe and mangiferin on primary human lymphocytes and lymphoblastoid cells.201424267799
alleviation of transient global ischemia/reperfusion-induced brain injury in rats with 1,2,3,4,6-penta-o-galloyl-β-d-glucopyranose isolated from mangifera indica.present study was undertaken to evaluate the protective effect of 1,2,3,4,6-penta-o-galloyl-β-d-glucopyranose (pgg) against transient global ischemia/reperfusion (i/r)-induced brain injury in rats. sixty minutes of global ischemia, followed by 24h of reperfusion caused significant alterations in cognition and memory (p<0.01), significant deterioration of motor coordination, grip strength, and limb tone (p<0.01) associated with neurological deficit. in addition, significant decrease in catalase ( ...201324157980
[can fruits and vegetables be used as substitute phantoms for normal human brain tissues in magnetic resonance imaging?].various custom-made phantoms designed to optimize magnetic resonance imaging (mri) sequences have been created and subsequently reported in jsrt. however, custom-made phantoms that correctly match the t1-value and t2-values of human brain tissue (gray matter and white matter) cannot be made easily or quickly. the aim of this project was to search for alternative materials, such as fruits and vegetables, for optimizing mri sequences. the following eight fruits and vegetables were investigated: ap ...201324140903
soya phospholipid complex of mangiferin enhances its hepatoprotectivity by improving its bioavailability and pharmacokinetics.mangiferin is a xanthonoid present in mangifera indica. it has been reported for a variety of pharmacological activities, including hepatoprotection. however, the major disadvantage of mangiferin is its reduced biological activity due to poor absorption, low bioavailability and rapid elimination from the body after administration. the aim of this study was to prepare a phospholipid complex of mangiferin to overcome these limitations and to investigate the impact of the complex on hepatoprotectiv ...201424114670
mapping of an ultrasonic bath for ultrasound assisted extraction of mangiferin from mangifera indica leaves.the present work deals with the mapping of an ultrasonic bath for the maximum extraction of mangiferin from mangifera indica leaves. i3(-) liberation experiments (chemical transformations) and extraction (physical transformations) were carried out at different locations in an ultrasonic bath and compared. the experimental findings indicated a similar trend in variation in an ultrasonic bath by both these methods. various parameters such as position and depth of vessel in an ultrasonic bath, diam ...201424103364
the peel and pulp of mango fruit: a proteomic samba.combinatorial peptide ligand libraries (cplls) have been adopted for investigating the proteomes of mango peel and pulp as well their peptidome content (the latter as captured with a c18 resin). the aim of this study was not only to perform the deepest investigation so far of the mango proteome, but also to assess the potential presence of allergens and of peptides endowed with biological activities. the proteins of peel and pulp have been captured under both native and denaturing extraction tec ...201324056186
effect of the moisture content of forced hot air on the postharvest quality and bioactive compounds of mango fruit (mangifera indica l. cv. manila).the effectiveness of hot air treatments in controlling decay and insects in mango fruit has been demonstrated and has usually been assessed as a function of the temperature of the heated air and the duration of the treatment. however, the contribution of the moisture content of the heated air has received little attention, especially with regard to fruit quality. in this study, mango fruits (cv. manila) at mature-green stage were treated with moist (95% relative humidity (rh)) or dry (50% rh) ho ...201424022858
pre-storage application of oxalic acid alleviates chilling injury in mango fruit by modulating proline metabolism and energy status under chilling stress.effects of oxalic acid on chilling injury, proline metabolism and energy status in mango fruit were investigated after mango fruit (mangifera indica l. cv. zill) were dipped in 5mm oxalic acid solution for 10min at 25°c and then stored at low temperature (10±0.5°c) for 49days thereafter transferred to 25°c for 4days. pre-storage application of oxalic acid apparently inhibited the development of chilling injury, notably elevated proline accumulation actually associated with increase in δ(1)-pyrro ...201424001814
mechanisms underlying the antinociceptive effect of mangiferin in the formalin test.the purpose of this study was to investigate the possible antinociceptive effect of mangiferin, a glucosylxanthone present in mangifera indica l., in inflammatory pain. furthermore, we sought to investigate the possible mechanisms action that contributes to these effects. the ipsilateral local peripheral (1-30 µg/paw), intrathecal (1-30 µg/rat) and oral (1-30 mg/kg) administration of mangiferin produced a dose-dependent reduction in formalin-induced nociception. the antinociceptive effect of thi ...201323973647
comparison of microwave-assisted and conventional extraction of mangiferin from mango (mangifera indica l.) leaves.mangiferin is the main bioactive component in mango leaves, which possesses anti-inflammatory, antioxidative, antidiabetic, immunomodulatory, and antitumor activities. in the present study, a microwave-assisted extraction method was developed for the extraction of mangiferin from mango leaves. some parameters such as ethanol concentration, liquid-to-solid ratio, microwave power, and extraction time were optimized by single-factor experiments and response surface methodology. the optimal extracti ...201323929791
characterization of three novel isoprenyl diphosphate synthases from the terpenoid rich mango (cv. alphonso) is popular due to its highly attractive, terpenoid-rich flavor. although alphonso is clonally propagated, its fruit-flavor composition varies when plants are grown in different geo-climatic zones. isoprenyl diphosphate synthases catalyze important branch-point reactions in terpenoid biosynthesis, providing precursors for common terpenoids such as volatile terpenes, sterols and carotenoids. two geranyl diphosphate synthases and a farnesyl diphosphate synthase were isolated fr ...201323911730
emissions of putative isoprene oxidation products from mango branches under abiotic stress.although several per cent of net carbon assimilation can be re-released as isoprene emissions to the atmosphere by many tropical plants, much uncertainty remains regarding its biological significance. in a previous study, we detected emissions of isoprene and its oxidation products methyl vinyl ketone (mvk) and methacrolein (macr) from tropical plants under high temperature/light stress, suggesting that isoprene is oxidized not only in the atmosphere but also within plants. however, a comprehens ...201323881400
regulation of lipid and glucose homeostasis by mango tree leaf extract is mediated by ampk and pi3k/akt signaling pathways.ethanolic extract of mangifera indica (mango) dose-dependently decreased serum glucose and triglyceride in kk-a(y) mice. our in vitro and in vivo investigations revealed that the effect of mango leave extract (me) on glucose and lipid homeostasis is mediated, at least in part, through the pi3k/akt and ampk signaling pathway. me up-regulated the expression of pi3k, akt and gys genes by 2.0-fold, 3.2-fold, and 2.7-fold, respectively, leading to a decrease in glucose level. on the other hand, me up ...201323871039
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