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differentiation of actively and passively acquired complement-fixing antibodies in infants with respiratory syncytial virus infection. 19704318079
direct immunofluorescent studies of infection with respiratory syncytial virus. 19704324105
interferon and respiratory syncytial virus. 19704190538
a respiratory syncytial virus of bovine origin. 19704195627
morphogenesis of respiratory syncytial virus in a green monkey kidney cell line (vero).the structure and morphogenesis of respiratory syncytial (rs) virus particles in a green monkey kidney cell line (vero) were examined. infected cells contained dense intracytoplasmic inclusions composed of filamentous structures. in places where inclusion material was associated with membranes, structural modifications were induced. there was a thickening of the membrane and an addition of projections 12 to 15 nm in length. the same changes were most frequently observed after association of isol ...19704100527
[radiological aspects of acute respiratory disorders of childhood caused by influenzae, parainfluenzae and respiratory syncytial viruses]. 19709082353
interferon and respiratory syncytial virus. 19714105357
late stage synchronization of respiratory syncytial virus replication. 19714106351
[fast postmortem diagnosis of adenovirus, para-influenza respiratory-syncytial virus diseases in children]. 19714326274
[the associative interrelationships of mycoplasma pneumoniae and respiratory-syncytial virus in cell cultures]. 19714327855
the tecumseh study of respiratory illness. 3. incidence and periodicity of respiratory syncytial virus and mycoplasma pneumoniae infections. 19714328570
the association of viruses with clinical pertussis.this study describes the results of attempts to grow viruses from per-nasal swabs taken from 136 children with clinical pertussis.altogether 37 strains of a variety of different viruses were isolated. adenovirus was the most frequent, making up 30% of the total. besides these, herpes simplex, measles, influenza a2, influenza b, mumps, poliovirus and respiratory syncytial virus were detected.bordetella pertussis was isolated from 22% of the cases.it appears that a pertussis-like syndrome can be c ...19714328794
experiences in laboratory diagnosis of respiratory syncytial virus infections in routine medical practice. 19714328892
clinical and immunological response of infants and children to administration of low-temperature adapted respiratory syncytial virus. 19714330595
antibodies to respiratory syncytial virus in a normal community in chandigarh area, northern india.a survey for the presence of respiratory syncytial (rs) virus antibodies has been carried out in 346 sera from a healthy community in northern india. the results showed that 19.6% of the sera were positive and had a titre of 16 or more. the higher titres were observed more frequently in the younger age groups. there is, therefore, serological evidence for the occurrence of rs virus infection in india.19714333697
[paramyxoviruses, with special reference to the parainfluenza virus and the respiratory syncytial virus and their diseases]. 19714321879
respiratory syncytial virus in hospital cross-infection.during an epidemic of respiratory syncytial (r.s.) virus in newcastle upon tyne 13 children developed r.s. virus infections while in hospital with other conditions. r.s. virus infection was also noted in four members of the staff. in two of the hospital wards outbreaks developed. all children infected with r.s. virus developed symptoms. the symptoms varied with age; two children aged 2 months or less developed colds, as did five children over 1 year of age. one child of 15 months with werdnig-ho ...19715569549
respiratory syncytial virus infection in infancy and childhood in a community in chandigarh. 19715574375
attempts to demonstrate hemagglutination and hemadsorption by respiratory syncytial virus.extensive attempts to demonstrate a hemagglutinin of respiratory syncytial virus by both hemagglutination and hemadsorption tests failed. hemagglutination tests were performed with red blood cells from 12 different animal species and at various temperatures and ph.19714998352
growth of respiratory syncytial virus in suspension cell culture.respiratory syncytial virus, burnett strain, adsorbed efficiently and grew to high titers in suspension cultures of hep-2 and ma-160 cells. our results compared favorably with previous experience with the growth of respiratory syncytial virus in monolayer cell cultures. the use of suspension cell cultures provides a convenient and simple procedure for producing high-titering respiratory syncytial virus pools.19715002897
isolation of respiratory syncytial virus from cattle in britain. 19715091097
experimental respiratory syncytial virus infection of adults. possible mechanisms of resistance to infection and illness. 19715091954
[anticomplementary and antigenic properties of complement-fixing antigens of respiratory syncytial virus]. 19715105628
pathogenesis of respiratory syncytial virus diseases in infancy. 19715118060
the role of the interferon system in respiratory syncytial virus infections. 19715131599
[obtaining rubella and respiratory syncytial virus complement-fixing antigen of increased activity]. 19715137549
[comparative studies with the neutralization test and complement fixation test in the diagnosis of respiratory syncytial virus infections]. 19715157476
respiratory syncytial virus infection in children in west bengal. 19715161563
observations on clinical and immunofluorescent diagnosis of parainfluenza virus infections.immunofluorescent techniques have been applied to nasopharyngeal secretions for the rapid diagnosis of parainfluenza virus types 1, 2, and 3 infections. seventy-five infections were found by isolation techniques; 55 of these had nasopharyngeal secretions taken and 53 were positive by direct examination. a comparison of the results of 60 neutralization tests with immunofluorescence applied to monkey kidney isolations showed complete agreement. immunofluorescence appeared to be a satisfactory meth ...19714323868
rapid diagnosis of respiratory syncytial virus infection in children by the immunofluorescent technique.the immunofluorescent examination of nasopharyngeal secretions has been compared with conventional cell culture for the diagnosis of respiratory syncytial (rs) virus infection in children under the age of 2 years in newcastle upon tyne and manchester. two hundred and sixty-eight identifications of rs virus were made by the fluorescent method, of which 258 (96%) were confirmed culturally. in 267 children from whom virus was isolated in cell culture a positive diagnosis was made by the fluorescent ...19714933660
evaluation of a temperature-sensitive mutant of respiratory syncytial virus in adults. 19714940177
[antigenic dissociation of the morphologic structures and heterogenicity of antibodies detected by immunofluorescence with respiratory syncytial virus]. 19714944789
respiratory syncytial virus in hospital cross-infection. 19725008363
agar gel precipitation reaction with respiratory-syncytial virus antigen. 19724400677
the rs-virus-infected cell in vitro. i. the nucleocytoplasmic (p=n) ratio following infection with the respiratory syncytial virus. 19724660917
[long-term observations of the blood level of antibodies to respiratory syncytial virus in children of a children's home]. 19724664100
[isolation of respiratory syncytial virus. apropos of a study of an epidemic outbreak]. 19724351873
hl cells, a sensitive line for the isolation and propagation of respiratory syncytial virus. 19724338798
adenovirus, parainfluenza virus and respiratory syncytial virus antibodies in the sera of jamaicans.surveys for respiratory virus antibodies in the jamaican population have shown that adenovirus, respiratory syncytial virus and parainfluenza types 1 and 3 virus antibodies are acquired early in life. the incidence of haemagglutination-inhibiting antibodies to parainfluenza viruses increases rapidly with age and almost all adults possess parainfluenza type 3 antibody, usually in high titre. parainfluenza type 1 antibodies are only slightly less common. complement-fixing antibodies to the adenovi ...19724341999
[the role of respiratory syncytial virus in bronchopulmonary pathology in adults]. 19724343035
immunofluorescence for routine diagnosis of respiratory syncytial virus infection.a comparison of immunofluorescent tests for the diagnosis of respiratory syncytial (rs) virus infections was carried out on 42 hospitalized cases of respiratory infection in childhood. respiratory syncytial virus was detected in 22 (52%) cases, the most sensitive method of detection being by indirect immunofluorescence of bristol hela tissue cultures inoculated with nasopharyngeal aspirates. the highest detection rate was in bronchiolitis cases (92%). detection of antibody rises in paired sera, ...19724345816
bovine respiratory syncytial virus. studies on an outbreak in japan, 1968-1969. 19724345977
the cytochemistry of inclusion bodies in cell cultures into which respiratory syncytial virus has been inoculated. 19724112282
[study of the antiviral action of actinomyces extracts on the multiplication of the respiratory syncytial virus in cell cultures]. 19724197601
structure of bovine respiratory syncytial virus. 19734121663
morphogenesis and ultrastructure of respiratory syncytial virus.respiratory syncytial (rs) virus was grown in vero cells and fixed for electron microscopy at various stages of maturation. both filamentous and round or kidney-shaped particles, either with (complete) or without (incomplete) internal structure, were observed. all four morphological forms were identical with respect to their reactivity with ferritin-labeled antibody to rs virus. freezeetching revealed a structural feature apparently unique for rs virus, namely helical striations around the core ...19734128827
[comparative observations of the level of antibodies to respiratory syncytial virus and parainfluenza virus type 3 in children at a children's home]. 19734350233
safety and antigenicity of temperature sensitive (ts) mutant respiratory syncytial virus (rsv) in infants and children. 19734353352
epidemiology of respiratory syncytial virus infection among infants and children in chicago. 19734353439
genetic studies of respiratory syncytial virus temperature-sensitive mutants. 19734353797
epidemiology of respiratory syncytial virus infection in washington, d.c. i. importance of the virus in different respiratory tract disease syndromes and temporal distribution of infection. 19734355005
epidemiology of respiratory syncytial virus infection in washington, d.c. ii. infection and disease with respect to age, immunologic status, race and sex. 19734355170
epidemiology of respiratory syncytial virus infection in washington, d.c. 3. composite analysis of eleven consecutive yearly epidemics. 19734355632
pediatric infections with respiratory syncytial virus. 19734357141
respiratory syncytial virus infections in children in montreal: a retrospective study.seventy-seven hospitalized children from whom respiratory syncytial virus was subsequently isolated were studied in retrospect. this demonstrated the association of host invasion by this agent with an acute respiratory disease requiring hospitalization for approximately one week.boys considerably outnumbered girls, the average age was 7.5 months, and in 56% the admission diagnosis was "bronchiolitis". cough and difficulty in breathing were the most common presenting complaints and "pneumonia" th ...19734357142
serological evidence of respiratory syncytial virus infection in sheep. 19734357318
respiratory syncytial virus infections. 19734806397
an outbreak of respiratory syncytial virus infection in an infant nursery. 19734512085
physicochemical properties of bovine respiratory syncytial virus. 19734541937
stimulated growth of respiratory syncytial virus in the presence of actinomycin d. 19734543050
letter to the editor: immunofluorescent techniques for the diagnosis of respiratory syncytial virus. 19734584350
attenuated respiratory syncytial virus vaccines in asthmatic children. 19744601222
rapid virus diagnosis in paediatric units by postal service. respiratory syncytial virus infection in cumberland. 19744605010
bovine parvovirus 1, bovine syncytial virus, and bovine respiratory syncytial virus and their infections. 19744608633
complete heart block and respiratory syncytial virus infection. 19744810281
separation and concentration of respiratory syncytial virus (rsv) antigens. 19744827015
isolation of rna species from hela cells infected with respiratory syncytial virus. 19744827262
genetic alteration in a temperature-sensitive mutant of respiratory syncytial virus after replication in vivo. 19744827725
isolation of respiratory syncytial virus from calves with acute respiratory disease. 19744842339
serological evidence for the association of bovine respiratory syncytial virus with respiratory tract disease in alabama cattle.a serological investigation for neutralizing antibody to bovine respiratory syncytial virus (brsv) was conducted using an antigenically related human strain of respiratory syncytial virus. results demonstrated the effectiveness of the procedure. sixty-seven percent of healthy, adult cattle tested were found to have antibody to brsv. calves in several herds were exposed to conditions to encourage development of respiratory tract disease. in three herds in which respiratory tract disease subsequen ...19744854249
bovine-testis cells for routine isolation of respiratory syncytial virus from infants. 19744857798
the radiological findings in respiratory syncytial virus infection in children. ii. the correlation of radiological categories with clinical and virological findings. 19744423578
biophysical characteristics of respiratory syncytial virus. 19744465906
sero-epidemiological survey of respiratory syncytial virus infection in pondicherry area--south india. 19744468943
studies on respiratory syncytial virus. ii. stabilization of respiratory syncytial virus. 19744479498
virus isolations from patients in general practice, 1961-71.during the period 1961-71 of 1785 viruses isolated from patients in the general population 503 (28%) were rhinoviruses, 465 (26%) influenza viruses, 248 (14%) enteroviruses, 234 (13%) herpes simplex virus, 132 (7%) parainfluenza viruses, 129 (7%) adenoviruses and 49 (3%) respiratory syncytial virus. also isolated were 18 strains of mumps virus, 7 coronaviruses and 295 streptococci of groups a, c or g.fluctuations were observed in the frequency with which respiratory syncytial virus, parainfluenz ...19744362413
virological findings and blood gas tensions in acute lower respiratory tract infections in children.sequential blood gas tensions and ph have been measured in 84 children selected from 486 admitted to hospital during a 15-month period with acute lower respiratory tract infections. of those selected 73 were treated conservatively and 11 by intermittent positive-pressure ventilation; one infant in the latter group died. respiratory syncytial virus (r.s.v.) was isolated from 24 out of 62 patients studied and the main pathogen in the most severely affected infants. statistical analysis showed that ...19744366122
acute respiratory failure in bronchiolitis and pneumonia in infancy. modes of presentation and treatment.the modes of presentation and the management of acute respiratory failure in 11 infants with severe lower respiratory tract infections (due to respiratory syncytial virus in eight) are described. progressive respiratory difficulties leading to exhaustion, peripheral circulatory collapse, recurrent apnoeic attacks, or generalized convulsions were the main clinical presentations resulting in severe ventilatory failure. in nine infants preventilation carbon dioxide tensions exceeded 65 mm hg. it se ...19744366123
respiratory syncytial virus in infants and children. 19744373702
the tecumseh study of respiratory illness. vii. further observations on the occurrence of respiratory syncytial virus and mycoplasma pneumoniae infections.the occurrence of infection with respiratory syncytial (rs) virus and mycoplasma pneumoniae was determined over a 6-year period among residents of tecumseh, michigan by isolation and serology. rs virus infection was detected for a variable time each year during the months extending from november to may. there was little viral activity in intervals between these periods of prevalence, which occurred on an alternating short-long cycle. higher infection rates were detected in periods preceding the ...19744374887
[respiratory syncytial virus infection in adults]. 19744377451
letter: growth of respiratory syncytial virus in rk13 cells. 19744136913
bovine respiratory syncytial virus: host range in laboratory animals and cell cultures. 19744209456
the radiological findings in respiratory syncytial virus infection in children. part i. definitions and interobserver variation in the assessment of abnormalities on the chest x-ray. 197415822330
letter: temporary paralysis after infection by respiratory syncytial virus. 197547500
myxoviruses.myxoviruses can be divided into 2 groups, orthomyxoviruses and paramyxoviruses. the former comprise the influenza group which is subdivided into types a,b and c. influenza b and c are purely human pathogens but influenza a, which includes a large number of antigenic subtypes, occurs in nature in pigs, horses, birds and man. all influenza a viruses irrespective of origin are chemically, biologically and genetically related. the epidemics which they cause are curious and puzzling and are an import ...197547825
secretory component and sudden-infant-death syndrome.post-mortem specimens of blood, respiratory-tract washings, bronchopulmonary tissue, spleen, and thymus were examined for respiratory viruses, immunoglobulins, and secretory component (s.c.) in eight infants with sudden-infant-death syndrome (s.i.d.s) and in eight other (control) infants with an identifiable cause of death. serum-immunoglobulin levels were similar in infants with s.i.d.s. and in control infants. in some s.i.d.s. cases serum-igm was slightly raised. respiratory syncytial virus wa ...197551192
[methods of obtaining standard diagnostic sera to respiratory syncytial virus]. 197557269
survey of adenovirus and respiratory syncytial virus antibodies in pondicherry area--south india. 1975175011
[recognition of influenza and other acute respiratory virus infections and their combinations by means of immunofluorescence].the results of postmortem examinations performed in 237 fatal cases of influenza and other acute respiratory diseases are presented. in smears of organs and tissue culture cells infected with these materials and heart blood the immunofluorescent procedure detected influenza virus antigens in 67% of the cases, antigens of other respiratory viruses in 53% including 18-19% of mixed infections. parallel immunofluorescent studies in living patients and isolation of influenza virus and adenoviruses in ...1975176823
clinically useful method for the isolation of respiratory syncytial virus.a simple method for the isolation of respiratory syncytial virus (rsv) is reported; it is relatively rapid and results in a high frequency of recovery of virus. a nasal secretion specimen with high titers of virus is inoculated at the bedside onto susceptible cell lines to avoid loss of viral infectivity due to liability of the virus. during an outbreak of rsv, viral specimens were obtained by this method from all young children admitted to the hospital with lower respiratory tract disease. rsv ...1975162921
the tecumseh study of respiratory illness. viii. acute infection in chronic respiratory disease and comparison groups.individuals with chronic lung disease and their families were selected from the tecumsch community along with similarly selected families as comparison groups and studied for 1-year periods. occurence of acute respiratory illness was ascertained weekly by telephone and calculated as an annual rate. persons with chronic bronchitis not only experienced more acute lower respiratory illness than healthy comparison subjects, but total illness rates were somewhat higher as well. infection rates were d ...1975163065
virus development in enucleate cells: echovirus, poliovirus, pseudorabies virus, reovirus, respiratory syncytial virus and semliki forest virus.a group of rna viruses, echovirus, poliovirus, reovirus, respiratory syncytial virus and semliki forest virus have been examined for ability to grow in enucleate african green monkey kidney (bsci) cells. semliki forest virus produced an almost normal yield of virus but poliovirus, echovirus, reovirus and respiratory syncytial virus, although showing clear evidence of virus replication when compared with a nuclear dna virus (pseudorabies virus) gave much lower yields than those from nucleate cell ...1975163289
an outbreak of severe pneumonia due to respiratory syncytial virus in isolated arctic populations.a rapidly developing outbreak of pneumonia in young infants was documented in two isolated artic populations in may 1972. these were studied virologically, serologically and clinically. in addition to the two stricken communities, one apparently unaffected with serious clinical illness and a fourth, in which are located the major hospital and airport in the eastern arctic, were also studied. one hundred and twenty-four patients were studied serologically and 81 respiratory and other specimens we ...1975163574
potential of attenuated respiratory syncytial virus vaccine for infants and children.respiratory syncytial virus (rsv) disease is a major cause of death and hospitalization in infancy and a frequent cause of morbidity throughout childhood. serum antibody does not protect as is evident from the study of natural disease and use of killed vaccines. local antibody responses occur in natural illness. possibly serum antibody in the absence of local antibody plays a part in illness. we have studied local and serum antibody response to potential attenuated vaccines: a 26 degrees c adapt ...1975165119
serologic profile of children in a mexican highland community: prevalence of complement-fixing antibodies to mycoplasma pneumoniae, respiratory syncytial virus and parainfluenza viruses.the study investigated the prevalence of antibodies to five leading agents of childhood respiratory disease in the county of huixquilucan, mexico. tests of sera from a random sample of children between 3 months and 18 years of age confirmed serologically the presence of mycoplasma pneumoniae, respiratory syncytial (rs) virus and parainfluenza 1, 2 and 3 viruses in this relatively isolated highland community. highest overall antibody frequency of 64.2% was seen for parainfluenza 3, and antibody t ...1975165720
experimental infection of calves with respiratory syncytial virus.three bovine isolates and one human isolate of rs virus were given intranasally to gnotobiotic, colostrum-deprived and conventional calves. all isolates produced a biphasic pyrexia associated with a serous nasal discharge. virus was recovered from nasal secretions 4-10 days after inoculation from nasal, tracheal and bronchial mucosae and lung of animals killed 7-13 days after inoculation. infection did not produce any macroscopic lesions, but histologically there was a focal degenerative rhiniti ...1975167410
new human adenovirus isolated from a renal transplant recipient: description and characterization of candiate adenovirus type 34.an antigenically distinct adenovirus is described which was isolated in march 1972 from the urine of a 17-year-old caucasian male who was experiencing fever after receiving a kidney transplant from a cadaver in february. the adenovirus could not be isolated in april from a pharyngeal swab which yielded cytomegalovirus. complement-fixation, hemagglutination-inhibition, and/or serum-neutralization tests on sequential serum specimens from the patient confirmed that the adenovirus infection occurred ...1975170313
physicochemical and serological characteristics of respiratory virus fluorescein-isothiocyanate conjugates for fluorescent-antibody diagnosis.fluorescein-isothiocyanate (fitc) conjugates were prepared by improved methods from standard reference antisera to influenza a and b, mumps, parainfluenza 1, 2, 3, and 4, herpesvirus, respiratory syncytial virus, and adenovirus hexon. the antisera, prepared in a variety of animals, were fractionated three times with selected optimal concentrations of ammonium sulfate and yielded gamma globulins of adequate purity for conjugation with fitc. conjugates containing optimal fluorescein-to-protein rat ...1975170315
[respiratory tract infections of viral origin in infants. examination of 103 serum pairs in autumn and following spring].in autumn 1973 und about four months later in spring 1974 blood samples were taken from the same 103 children aged from a few months to five years and coming from different parts of bavaria. we examined the samples for complement-fixing antibodies against the influenza virus types a, b and c, the parainfluenza virus types 1, 2 and 3, the adenoviruses and the respiratory-syncytial virus, and for neutralising antibodies against the echo virus type 25. at the commencement of the investigation the m ...1975172769
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