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induction of protective effector immunity to prevent pathogenesis caused by the respiratory syncytial virus. implications on therapy and vaccine design.human respiratory syncytial virus (hrsv) is the leading cause of respiratory illness in infants and young children around the globe. this pathogen, which was discovered in 1956, continues to cause a huge number of hospitalizations due to respiratory disease and it is considered a health and economic burden worldwide, especially in developing countries. the immune response elicited by hrsv infection leads to lung and systemic inflammation, which results in lung damage but is not efficient at prev ...024801878
alternatives to retroorbital blood collection in hispid cotton rats (sigmodon hispidus).cotton rats (sigmodon hispidus) are a valuable animal model for many human viral diseases, including polio virus, measles virus, respiratory syncytial virus, and herpes simplex virus. although cotton rats have been used in research since 1939, few publications address handling and sampling techniques for this species, and the retroorbital sinus remains the recommended blood sampling site. here we assessed blood sampling methods that are currently used in other species and a novel subzygomatic sa ...022776125
targeting rsv with vaccines and small molecule drugs.respiratory syncytial virus (rsv) is the most significant cause of pediatric respiratory infections. palivizumab (synagis®), a humanized monoclonal antibody, has been used successfully for a number of years to prevent severe rsv disease in at-risk infants. however, despite intense efforts, there is no approved vaccine or small molecule drug for rsv. as an enveloped virus, rsv must fuse its envelope with the host cell membrane, which is accomplished through the actions of the fusion (f) glycoprot ...022335496
detecting specific infections in children through host responses: a paradigm shift.there is a need for improved diagnosis and for optimal classification of patients with infectious diseases. an alternative approach to the pathogen-detection strategy is based on a comprehensive analysis of the host response to the infection. this review focuses on the value of transcriptome analyses of blood leukocytes for the diagnosis and management of patients with infectious diseases.024739346
isolation of the respiratory syncytial virus from a patient with pneumonia. 196013744117
respiratory syncytial virus. iii. production of illness and clinical observations in adult volunteers. 196113754148
studies of acute respiratory illnesses caused by respiratory syncytial virus. 2. epidemiology and assessment of importance. 196113773790
respiratory syncytial virus. i. virus recovery and other observations during 1960 outbreak of bronchiolitis, pneumonia, and minor respiratory diseases in children. 196113692354
respiratory syncytial virus in britain. 196113733735
studies of acute respiratory illnesses caused by respiratory syncytial virus. 3. clinical and laboratory findings. 196113740533
epidemic bronchiolitis and pneumonitis related to respiratory syncytial virus. 196113681401
relationship of pneumonitis in infants to respiratory syncytial virus. 196113859340
respiratory syncytial virus. iv. correlation of virus shedding, serologic response, and illness in adult volunteers. 196113790307
epidemic bronchiolitis caused by a respiratory syncytial virus: clinical aspects. 196113893998
studies of acute respiratory illnesses caused by respiratory syncytial virus. 1. laboratory findings in 109 cases. 196113711106
an outbreak of febrile illness and pneumonia associated with respiratory syncytial virus infection. 196114453700
respiratory syncytial virus. ii. serologic studies over a 34-month period of children with bronchiolitis, pneumonia, and minor respiratory diseases. 196113732993
respiratory syncytial virus. 196120326947
respiratory syncytial virus. 196120789173
relationship between respiratory syncytial virus and newcastle disease-parainfluenza group. 196213999158
experimental infection with respiratory syncytial virus in several species of animals. 196214021817
[serological and clinical studies on virus diseases of the respiratory tract. ii. serological demonstration of infections with the respiratory syncytial virus]. 196213926324
respiratory syncytial virus in epidemic bronchiolitis of infants. 196214496855
natural reinfection of adults by respiratory syncytial virus. possible relation to mild upper respiratory disease. 196214452065
growth and serological characteristics of respiratory syncytial virus. 196213867292
acute respiratory diseases of viral etiology. iv. respiratory syncytial virus. 196213878129
the role of respiratory syncytial virus, para influenza viruses, and eaton agent in acute lower respiratory tract illness. 196213878130
immunofluorescence with respiratory syncytial virus. 196214456378
growth characteristics of respiratory syncytial virus. 196214452451
respiratory syncytial virus infection in the north west of england. 196314011008
a plaque assay for respiratory syncytial virus. 196314033060
respiratory syncytial virus. 196314064931
respiratory syncytial virus in acute exacerbations of chronic bronchitis. 196314066843
serological studies with respiratory syncytial virus. 196313936211
the isolation of respiratory syncytial virus from children with acute respiratory disease. 196313961503
direct and indirect fluorescent-antibody techniques for the psittacosis-lymphogranuloma venereum-trachoma group of agents.ross, martin r. (connecticut state department of health, hartford) and earle k. borman. direct and indirect fluorescent-antibody techniques for the psittacosis-lymphogranuloma venereum-trachoma group of agents. j. bacteriol. 85:851-858. 1963.-direct and indirect fluorescent-antibody (fa) techniques were developed for the detection of group antigen in infected tissue cultures and the titration of group antibody in human antiserum. the growth of the agent of meningopneumonitis (mp) in mouse embryo ...196314044954
occurrence of respiratory syncytial virus in acute respiratory diseases in infancy. 196314063052
antigenic differences between two strains of respiratory syncytial virus. 196314021818
an assay method for respiratory syncytial virus. 196314066121
a survey of antibodies to respiratory syncytial virus in the population. 196414120831
respiratory syncytial virus and parainfluenza myxoviruses as causal agents of acute respiratory infections in auckland children. 196414171936
serological study of respiratory syncytial virus infections in infancy and childhood. 196414211759
[respiratory syncytial virus (rs virus), a cause of severe pneumonia in infants. laboratory findings from 2 epidemics in the ulleval hospital]. 196414214666
problems of laboratory diagnosis of respiratory syncytial virus infection in childhood. 196414184629
[on disorders of the respiratory organs caused by respiratory syncytial virus]. 196414204134
study on the peculiarities of respiratory syncytial (rs) virus reproduction based on indices of enzymic activity. 196414245871
[pathogenic viruses of the respiratory tract and their methods of identification]. 196414250271
serological evidence of infection by respiratory syncytial virus in outbreak of acute bronchiolitis. 196414133606
[epidemic of acute bronchiolitis in infants. isolation of a respiratory syneytial virus]. 196414248325
respiratory syncytial virus: properties of strains propagated in monkey kidney cell cultures. 196414121638
acute respiratory illness in the premature nursery associated with respiratory syncytial virus infections. 196414243464
respiratory syncytial virus neutralizing antibodies in persons residing in chicago, illinois. 196414243465
survival of the respiratory syncytial virus during storage under various conditions. 196414245166
respiratory syncytial virus infections in children: a review. 196414198254
respiratory disease associated with parainfluenza and respiratory syncytial viruses. 196414199478
respiratory syncytial virus: observations on antigenic heterogeneity. 196414117451
clinical significance of respiratory syncytial virus. 196414163254
the sensitivity of grivet monkey kidney cell line bs-c-1 for propagation and isolation of certain human viruses. 196414215895
heparin and related polyionic substances as virus inhibitors. 196414227873
the incidence of complement-fixing antibodies to the respiratory syncytial virus in sera from danish population groups aged 0-19 years. 196414227887
rashes due to respiratory syncytial virus. 196414214181
[serological and virological studies of respiratory tract infections caused by respiratory syncytial virus, adenoviruses and other viruses]. 19644284117
[investigations on the occurrence of neutralizing antibodies against respiratory syncytial virus in the population]. 19654285440
[an outbreak of illnesses due to respiratory syncytial virus]. 19654290515
antibodies to respiratory syncytial virus in human sera from different regions of the world.since it was first isolated in 1956, respiratory syncytial (rs) virus has been found in many parts of the world, generally in association with human respiratory illness, especially of young children. previous studies have examined the frequency of serological evidence of infection in certain countries. the present study is a more general survey, dealing with the prevalence of rs virus antibody in sera from 14 different countries widely separated geographically. there was evidence of infection in ...19655294309
[respiratory syncytial virus]. 19655320804
an immunofluorescent staining method for rapid identification of respiratory syncytial virus. 19655322294
serological studies with respiratory syncytial virus. 19655858543
respiratory syncytial virus infection. 19655835473
an outbreak among children of respiratory illness caused by respiratory syncytial virus. a serological and clinical study. 19655832143
inner component of respiratory syncytial virus. 19655854596
respiratory syncytial virus infection and its serologic epidemiology. 19655854688
rashes due to respiratory syncytial viruses. 196514238693
immunofluorescent evidence of respiratory syncytial virus infection in cases of giant cell bronchiolitis in children. 196514270270
[infection by respiratory syncytial virus in pediatrics]. 196514303277
contracting chicken embryo heart cells in tissue culture. effect of viruses and other agents. 196514314192
[contribution to the ecology of the respiratory syncytial virus in czechoslovakia]. 196514344742
acute otitis media of viral origin and other pediatric problems in 1964. 196514348337
antibodies against respiratory viruses among healthy children. 196514343439
acute respiratory illness in children. a serological study with viral and bacterial antigens. 196514343443
morphology of subunits of respiratory syncytial (rs) virus. (brief report). 196514269259
respiratory syncytial virus studies on children hospitalized during an outbreak of respiratory illness in finland. 196514294413
acute respiratory disease in infancy and childhood: present understanding and prospects for prevention. 196514313363
transformation of cells by viruses. 196514330089
[respiratory syncytial virus infections in childhood. clinical aspects and pathological anatomy]. 19665902650
[respiratory syncytial virus infections in childhood. virologic studies]. 19665900940
an antigenic analysis of respiratory syncytial virus isolates by a plaque reduction neutralization test. 19665933417
isolation of respiratory syncytial virus from middle ear exudates of infants. 19665957733
use of human diploid cell cultures for primary isolation of respiratory syncytial virus. 19665902934
[epidemic due to respiratory syncytial virus in a children's community]. 19664292611
biophysical studies of respiratory syncytial virus. ii. identification of two soluble complement-fixing antigens of respiratory syncytial virus.forsyth, ben r. (national institute of allergy and infectious diseases, bethesda, md.), helen v. coates, and robert m. chanock. biophysical studies of respiratory syncytial virus. ii. identification of two soluble complement-fixing antigens of respiratory syncytial virus. j. bacteriol. 91:1270-1276. 1966.-column chromatography of concentrated preparations was used to separate two antigenic components from the "soluble complement-fixing (cf) antigen" of respiratory syncytial (rs) virus. these ant ...19665929755
[respiratory syncytial virus infections in finland]. 19665950729
acceleration of the growth of respiratory syncytial virus by proflavine. 19665956258
isolation of respiratory syncytial virus from middle ear exudates of infants. 19665963002
experimental inoculation of guinea pig's middle ear with respiratory syncytial virus. 19665992680
respiratory syncytial virus infections in childhood. 19665950003
biophysical studies of respiratory syncytial virus. i. density of respiratory syncytial virus and associated complement-fixing antigens in cesium chloride density gradient.coates, helen v. (national institute of allergy and infectious diseases, bethesda, md.), ben r. forsyth, and r. m. chanock. biophysical studies of respiratory syncytial virus. i. density of respiratory syncytial virus and associated complement-fixing antigens in a cesium chloride density gradient. j. bacteriol. 91:1263-1269. 1966.-concentrated fluids from respiratory syncytial (rs) virus-infected tissue cultures (hep-2 and bek) were subjected to equilibrium sedimentation in cesium chloride. when ...19665929754
[detection of complement fixing antibodies against respiratory syncytial virus in inhabitants of the city of são paulo]. 19665994234
[study of kb cells infected by myxovirus parainfluenzae 2, 3 or by respiratory syncytial virus. i. relation between viral multiplication and its cellular manifestations]. 19664286477
a roentgenographic analysis of respiratory syncytial virus pneumonia in infants. 19664288755
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