the development of an attenuated foot-and-mouth disease virus vaccine by modification and cloning in tissue cultures of bhk21 cells. 19694306372
surface structure of foot-and-mouth disease virus. 19694306712
the susceptibility of some australian fauna to infection with foot and mouth disease virus. 19684306882
changed environmental conditions affecting normal body temperature of mice and its effect on the multiplication of foot and mouth disease virus. 19694307099
the isolation of two enzyme-ribonucleic acid complexes involved in the synthesis of foot-and-mouth disease virus ribonucleic acid.the foot-and-mouth disease virus-rna polymerase complex was released from membrane particulates present in the cytoplasm of infected baby hamster kidney cells. the soluble polymerase complex was fractionated by zonal centrifugation in sucrose gradients. two polymerase complexes (rna and protein complex) active in the cell-free system were isolated and had s-rate ranges of 20-70s and 100-300s, respectively. the light polymerase complex contained 20s double-stranded rna; and the heavy polymerase c ...19694308096
effect of actinomycin d and guanidine on the formation of a ribonucleic acid polymerase induced by foot-and mouth-disease virus and on the replication of virus and viral ribonucleic acid.the rna-dependent rna polymerase induced in baby-hamster kidney cells by infection with foot-and-mouth-disease virus can be detected as early as 60min. after infection, which is 60min. before viral rna synthesis commences. the time at which the polymerase can first be detected coincides with the latest time at which actinomycin d (50mug./10(7) cells) or guanidine (1mg./10(7) cells) inhibits virus replication. however, by increasing the concentration of guanidine, viral replication can be inhibit ...19694308295
electrophoretic properties of foot-and-mouth disease virus strains and the selection of intra-strain mutants. 19694308489
the structure of foot-and-mouth disease virus protein. 19694308493
immunogenicity of nanogram to milligram quantities of inactivated foot-and-mouth disease virus. ii. comparative response of guinea pigs and steers. 19684308554
evidence for an internal antigen in foot-and-mouth disease virus. 19694308741
heat inactivation of foot-and-mouth disease virus in blood products. 19694308879
the isolation of foot-and-mouth disease virus from african buffalo (syncerus caffer). 19694309109
persistence of foot-and-mouth disease virus in lymph nodes and blood of experimentally infected buffalo-calves in west pakistan. 19694309241
[a study of replication of foot-and-mouth disease virus in infected cells]. 19684310522
viability of foot-and-mouth disease virus in oil emulsions. 19694311208
[an electron microscopic study of foot-and-mouth disease virus]. 19684311389
[biological properties of the a22 foot-and-mouth disease virus]. 19684311390
[isolation of foot-and-mouth disease virus from swine that is apathogenic to cattle]. 19684311392
[the viability of foot-and-mouth disease virus in air]. 19684311393
[appearance of infectious ribonucleic acid during a one-step growth cycle of foot-and-mouth disease virus in pig kidney cells]. 19684311471
airborne excretion of foot-and-mouth disease virus. 19694311577
electrophoretic characterization of foot-and-mouth disease virus-specific ribonucleic acid.foot-and-mouth disease virus (fmdv)-specific ribonucleic acid (rna) was analyzed by electrophoresis on 0.5% agarose gels. four classes of rna were resolved as a function of mobility in agarose: two classes of slowly migrating multistranded rna, the infectious viral rna with intermediate mobility, and a minor fast-moving class of lower-molecular-weight single-stranded rna. the major rna species were infectious viral rna and the slowest migrating class of multistranded rna. the latter rna was poly ...19694311799
inhibition of host cell ribosomal ribonucleic acid methylation by foot-and-mouth disease virus.a study of protein and ribonucleic acid (rna) synthesis in cells infected by foot-and-mouth disease virus has indicated possible mechanisms of viral control over host cell metabolism. foot-and-mouth disease virus infection of baby hamster kidney cells resulted in 50% inhibition of host cell protein synthesis at 180 min postinfection. a viral-induced interference with host cell rna methylation was observed to be more rapidly inhibited than protein synthesis. to determine the nature of methylation ...19694311801
[viral particle specific serums, used in complement fixation tests of foot-and-mouth disease virus]. 19694312138
[use of the ai variant of deproteinized foot-and-mouth disease virus in the production of vaccine]. 19684312578
[saponin vaccine from the ai variant of lapinized foot-and-mouth disease virus]. 19684312579
[inactivation of foot-and-mouth disease virus in the preparation of a complement fixing antigen]. 19684312586
[immunogenic properties of foot-and-mouth disease virus inactivated by various methods]. 19684312587
foot-and-mouth disease virus inhibition induced in mice by synthetic double-stranded rna (polyriboinosinic and polyribocytidylic acids).synthetic 2-stranded rna-a helical complex formed by duplexing homopolymers of polyriboinosinic and polyribocytidylic acids (poly i:c)-induced host resistance to foot-and-mouth disease virus when microgram quantities were injected into mice. there was a graded response as shown by titrations of polynucleotide complex or virus. protection was effective for >48 hours after a single injection of polynucleotide complex. survival and serum interferon titers were directly related.19694312754
an interferon-like inhibitor of foot-and-mouth disease virus induced by phytohemagglutinin in swine leukocyte cultures. 19694313026
inhibition of foot-and-mouth disease virus by normal bovine serum. 19704313160
continuation of studies on the incidence and distribution of different types of foot-and-mouth disease virus in india. 19694313319
target molecular weight of foot-and-mouth disease virus and poliovirus. 19704313710
[immunofluorescent study of the kinetics of the foot-and-mouth disease virus on cell cultures]. 19694313763
[preparation and control of variant sera for type o foot-and-mouth disease virus]. 19684314301
[comparative resistance of foot-and-mouth disease virus to formalin and hydroxylamine]. 19684314302
properties of temperature-sensitive mutants of the kenya 3/57 strain of foot-and-mouth disease virus. 19704314409
[a study of the properties of attenuated cold variant of type o foot-and-mouth disease virus]. 19694314613
[luminescent-cytochemical study of the growth of a22 foot-and-mouth disease virus in cell cultures]. 19694314924
[survival time of foot-and-mouth disease virus in the sewage of biological products factories]. 19694314925
[viability of foot-and-mouth disease virus in pastures]. 19694314926
[activated sepharose as immunoadsorbent in the foot-and-mouth disease virus system]. 19704315447
[culturing foot-and-mouth disease virus in vnk-21 cells in rotating vessels]. 19694315467
[purifying foot-and-mouth disease virus for electron microscopy]. 19694315468
[seroprotection reaction in suckling mice for identification of foot-and-mouth disease virus strains]. 19694315469
[disinfection of milk contaminated with foot-and-mouth disease virus at dairy plants]. 19694315470
some properties of carrier strains of foot-and-mouth disease virus. 19704315628
the effect of diethylaminoethyl dextran and agar overlay ph on plaque formation by two plaque-size variants of foot-and-mouth disease virus.the effect of diethylaminoethyl (deae) dextran and agar overlay medium ph on a small-plaque (sp) and large-plaque (lp) foot-and-mouth disease virus (fmdv), type a, strain 119 (a119) was studied. the sp virus was inhibited under normal agar overlay but the addition of 100, 1,000 and 2,000 microg deae dextran/ml of agar overlay permitted plaque development. by using untreated and deae dextran-treated agar overlay medium, plaque formation by the sp virus was enhanced when the ph of agar medium was ...19704315769
interferons of foot-and-mouth disease virus: a new assay for interferon. 19704315825
replication of foot-and-mouth disease virus ribonucleic acid. 19704315846
[concentration of foot-and-mouth disease virus by polyethylene glycol]. 19704315858
[analysis by zonal centrifugation in a saccharose gradient of viral particles contained in a preparation of the foot-and-mouth disease virus]. 19694315921
effect of actinomycin d on virus-induced ribonucleic acid polymerase formation in foot-and-mouth disease virus-infected baby hamster kidney cells.actinomycin d, at a concentration that inhibits cellular ribonucleic acid (rna) synthesis, inhibited the production of foot-and-mouth disease virus-induced rna polymerase in baby hamster kidney cells. inhibition was proportional to exposure time and reached 85% when actinomycin d was added 90 min before infection. polymerase production was inhibited to the same extent in growth and minimal media, and the kinetics of its appearance were slightly different than in untreated cells. enzyme preparati ...19674316246
effect of foot-and-mouth disease virus on protein synthesis and ribonucleic acid polymerase activity at various temperatures. 19704316392
[isolation of foot-and-mouth disease virus in sheep]. 19704316723
demonstration of three specific sites on the surface of foot-and-mouth disease virus by antibody complexing. 19704316776
[the disinfectant activity of iosan against foot and mouth disease virus]. 19704317444
typing of the foot-and-mouth disease virus. cumulative quarterly report. 19694317612
[typing of the foot-and-mouth disease virus]. 19694317613
comparison of cryobiological and freeze-drying characteristics of foot and mouth disease virus and of vesicular stomatitis virus. 19684317755
foot-and-mouth disease virus-induced alterations of baby hamster kidney cell macromolecular biosynthesis: inhibition of ribonucleic acid methylation and stimulation of ribonucleic acid synthesis.the kinetics of ribonucleic acid (rna) and protein synthesis and rna methylation were examined after foot-and-mouth disease virus (fmdv) infection of baby hamster kidney cells. the synthesis of rna extracted from the whole cells was stimulated two- to threefold above the control level of synthesis. this increased rate was attributed to viral rna synthesis. the inhibition of host rna methylation was concomitant with but more pronounced than protein synthesis inhibition. the methylation of transfe ...19704318088
attenuation of foot-and-mouth disease virus by chemical means. 19704318111
high mutation rate of foot-and-mouth disease virus treated with hydroxylamine. 19704318112
[enhancement, by addition of diethylaminoethyl-dextran, of the infectivity of ribonucleic acid from foot-and-mouth disease virus]. 19674318194
[the inactivation of foot-and-mouth disease virus by ethylethyleneimine and the use of the inactivated virus in the preparation of vaccines]. 19704318509
detection of foot-and-mouth disease virus antibodies. i. "passive" hemagglutination test.a passive hemagglutination test has been developed to detect and measure foot-and-mouth disease virus (fmdv) antibody by using glutaraldehyde as a coupling reagent. an optimal concentration of 10 to 40 mug of virus per ml with 0.25% glutaraldehyde at 25 c for 1 hr was established for the sensitization of sheep erythrocytes. a reaction time of 18 hr at 4 c or 2 hr at 37 c induced good agglutination in the presence of specific antibody. sensitization was carried out in phosphate buffer, whereas ag ...19704318573
plaque morphology of some south american strains of foot-and-mouth disease virus and the effects of polyionic compounds on plaque formation. 19704318576
foot-and-mouth disease virus: biological characteristics of virus from bovine carriers. 19704318578
immunochemical studies of foot-and-mouth disease. vii. characterization of foot-and-mouth disease virus concentrated by polyethylene glycol precipitation. 19704318624
[modification of the complement fixation test in determining the type of foot-and-mouth disease virus]. 19704318882
[identification of the types of foot-and-mouth disease virus. quarterly cumulative report]. 19684319366
[identification of the types of foot-and-mouth disease virus. nong-sarsaï (thailand). results of the diagnosis and identification of the foot-and-mouth disease virus]. 19684319367
characterization of foot-and-mouth disease virus ribonucleic acid synthesized in vitro. 19704319475
foot-and-mouth disease virus in milk: an epidemiological study. 19704319528
[classification of the foot-and-mouth disease virus strain responsible for the 1967 english epidemic]. 19704319822
an indirect ferritin-tagged antibody system for foot-and-mouth disease virus. 19704320102
adsorption of foot-and-mouth disease virus by muscle, kidney, lung and brain from infant and adult mice.adsorption of foot-and-mouth disease (fmd) virus by minced and homogenized muscle, kidney, lung, and brain from infant and adult mice was compared under various experimental conditions to determine if there were differences in adsorption characteristics. the following factors were studied: relative ability to adsorb virus, sedimentation of the adsorbing components, heat lability of the components, virus elution, and recovery of cell-associated virus. the results indicated that the adsorbing comp ...19704320205
susceptibility of the agouti (dasyprocta aguti) to foot-and-mouth disease virus. 19694320315
quantitation of the antigenicity and immunogenicity of purified foot-and-mouth disease virus vaccine for swine and steers.the antigenicity and immunogenicity of a purified preparation of foot-and-mouth disease virus [type a(12), strain 119 (fmdv a-119)] inactivated with 6.0 mmn-acetylethylenimine at 37 c were compared in swine and steers. three antigen doses were tested, 640, 160, and 40 ng. in accordance with findings for guinea pigs, as previously determined by dose-response curves, as little as fourfold changes in antigen in the region of the minimum effective dose produced marked differences in the serological ...19704320865
further investigations on the airborne excretion of foot-and-mouth disease virus.calf thyroid tissue cultures were found to be the most sensitive system in detecting virus collected in a large volume air sampler from boxes, where cattle, sheep and pigs infected with a and c strains of foot-and-mouth disease (fmd) virus were housed. it was confirmed with all strains of fmd virus tested that pigs excreted the most virus followed by cattle and sheep, but there was variation between strains, the highest virus recoveries being obtained from animals infected with o(1) and c novill ...19704321594
ihalation, persistence and dispersal f foot-and-mouth disease virus by man.sampling of human subjects, who had been in contact with animals infected with foot-and-mouth disease (fmd) virus, showed that virus could be recovered from the nose, throat, saliva and from air expelled during coughing, sneezing, talking and breathing. the amounts of virus recovered paralleled those collected with a large-volume sampler and multistage impinger and these findings confirmed that the highest recovery of airborne virus was from infected pigs followed by cattle and sheep. more virus ...19704321595
foot-and-mouth disease virus antibodies: comparison of a tissue culture microneutralization test with the assay in suckling mice.a microneutralization test for foot-and-mouth disease virus antibodies is described and compared to the standard mouse test.19704321714
survival of foot-and-mouth disease virus on meat packaging materials. 19694322826
temperature-dependent interferon-sensitivity of foot-and-mouth disease virus. 19704322840
effects of temperature on viral rna synthesis and rna polymerase activity in a foot-and-mouth disease virus system. 19704322848
foot-and-mouth disease virus: rapid assay using the fluorescent antibody technique. 19704322849
[identification of the types of foot-and-mouth disease virus]. 19704323105
[identification of the types of foot-and-mouth disease virus]. 19704323109
[identification of the types of foot-and-mouth disease virus. nong-saraï (thailand)]. 19704323110
pathogenicity in mice of foot-and-mouth disease virus selected by adsorption with calf kidney. 19704323284
[structure and properties of foot-and-mouth disease virus (review)]. 19704323894
[antigenic properties of type c foot-and-mouth disease virus]. 19704323896
[peculiarities of a cold variant of foot-and-mouth disease virus (type o)]. 19704324049
persistence of foot-and-mouth disease virus in animals, their products and the environment. 19694324721
[the intraviral nature of photoinactivation of proflavin-sensitized foot-and-mouth disease virus]. 19704324754
[identification of types and variants of foot-and-mouth disease virus]. 19714325011
[foot and mouth disease virus in ultrathin sections]. 19714325012
[the effect of temperature during passage on the properties of attenuated foot and mouth disease virus]. 19714325013
[interference and sensitivity of virulent and attenuated foot-and-mouth disease virus to interferon]. 19714325014
[purification of cultured foot-and-mouth disease virus]. 19714325015
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