[etiological studies of epidemic hemorrhagic fever. i. virus isolation in apodemus agrarius from non-endemic area and its antigenic characterization]. 19826128079
epidemic hemorrhagic fever revisited.epidemic hemorrhagic fever is a disease characterized by phases of sequential fever, hypotension, oliguria, and polyuria. this disease represented a major hazard for american soldiers during the korean war (1950-1953) and is a persistent problem in asia, the ussr, and northern europe. advances in the etiology, epidemiology, and therapy of epidemic hemorrhagic fever are discussed.19826128779
new hemorrhagic fever with renal syndrome-related virus in rodents in the united states. 19826129495
other serotypes of hemorrhagic fever with renal syndrome viruses in europe. 19826129496
seroepidemiology of hantaan virus. 19826129497
serological diagnosis of hemorrhagic fever with renal syndrome in european region of u.s.s.r. 19826129499
viruses of classical and mild forms of haemorrhagic fever with renal syndrome isolated in china have similar bunyavirus-like morphology. 19836131283
[hemorrhagic fever with a renal syndrome in the maritime territory].the sporadic character of the occurrence of hemorrhagic fever with the renal syndrome in the primorye territory has been established. three rodent species have been found to be spontaneously infected with the causative agent of this disease. antibodies in patients with this disease are detected at its early stages and persist for a long time after convalescence. the possibility of the formation of a contingent immune to hemorrhagic fever, due to the persons who have had mild and asymptomatic for ...19836132506
etiologic studies of epidemic hemorrhagic fever (hemorrhagic fever with renal syndrome).two strains of epidemic hemorrhagic fever (ehf) virus were isolated from the lung tissues of apodemus agrarius mice that were captured in an area where ehf is endemic. the strains were isolated by passages in a. agrarius mice from a nonendemic area. identification of the isolates by usual procedures was confirmed by repeated blind tests with coded sera. contamination with certain known viruses such as reovirus, adenovirus (types 3 and 7), and other pathogens, such as murine typhus rickettsiae an ...19836132949
[serological studies of convalescent hemorrhagic fever patients with renal syndrome]. 19836133030
hemorrhagic fever with renal syndrome (hfrs). 19826134332
hemorrhagic fever with renal syndrome in finland: ecology and virology of nephropathia epidemica. 19826134333
clinical features of hfrs in scandinavia as compared with east asia. 19826134335
muroid virus nephropathies and muroid viruses of the hantaan virus group.hemorrhagic fever with renal syndrome (hfrs) came dramatically to the attention of western medicine in 1951 with the "new" disease becoming a major source of morbidity and mortality in american troops in korea. known there as epidemic hemorrhagic fever (ehf) or korean hemorrhagic fever (khf), it became apparent that it was the same disease as the endemic (epidemic) hemorrhagic nephroso-nephritis of the soviet far east and songo fever of the japanese army in manchuria. the conjecture that the mil ...19826134336
[identification of a strain of epidemic hemorrhagic fever (ehf) virus from patients' sera]. 19836134574
haemorrhagic fever with renal syndrome: memorandum from a who meeting.haemorrhagic fever with renal syndrome (hfrs) is a public health problem throughout most of the european and asian land mass. although predominantly associated with rural areas, it is now being recognized as an urban problem in some countries, and also presents a particular hazard to laboratory staff who use rodents for biomedical research. in wild rodents (rats, mice and voles) the infection is asymptomatic. human infection with the hfrs agent(s) is sporadic, but under special circumstances epi ...19836134591
immunofluorescence studies of disseminated hantaan virus infection of suckling mice.hantaan virus, the etiological agent of korean hemorrhagic fever, was inoculated intracerebrally or intraperitoneally into suckling mice, and the course of the infection was followed by infectivity titration and immunofluorescence studies. mice became ill and were moribund by 13 to 14 days postinfection. in mice inoculated either intracerebrally or intraperitoneally, virus antigen was present in brain, heart, lungs, liver, and kidney. less consistently, specific fluorescence was observed in sple ...19836134678
isolation of virus causing hemorrhagic fever with renal syndrome (hfrs) through a cell culture system.twenty-three rat lung specimens collected in outbreaks of hemorrhagic fever with renal syndrome (hfrs) in three medical institutions were inoculated onto the vero-e6 cell monolayers. after several blind passages, an agent growing serially in the cell cultures and reacting specifically with known hfrs-positive sera was isolated from two of these specimens. the two isolates were antigenically identical each other. the agent, named strain sr-11, was identified as the causative virus of hfrs by its ...19836134854
haemorrhagic fever with renal syndrome related virus in indigenous wild rodents in belgium. 19836134951
[etiological research on a mild type of hemorrhagic fever]. 19826136336
[advances in researches on the problem of etiology and sero-epidemiology of epidemic hemorrhagic fever]. 19826136339
[characteristics of the epizootic process of a natural foci of hemorrhagic fever with renal syndrome in small mammals trapped on the outskirts of ufa]. 19836136899
[immunological and zooparasitological characteristics of epizootics of hemorrhagic fever with renal syndrome in natural foci in the amur river region].in natural foci of hemorrhagic fever with renal syndrome (hfrs) located in agricultural landscapes, rodents of various species are infected with the virus, however, regular hfrs epizootics are observed in field mice which present the highest abundance of infected animals in the population. annually, a high direct correlation is observed between the population density of rodents and the percentage of animals with hfrs virus antigen in the blood and lungs. in 1981, there was a high correlation bet ...19836137110
adaptation to laboratory and wild animals of the haemorrhagic fever with renal syndrome virus present in the foci of european u.s.s.r. brief report.four strains of haemorrhagic fever with renal syndrome virus (hfrsv) from rodents or patients in european u.s.s.r. foci of hfrs were isolated in laboratory bred c. glareolus. the sensitivity of these animals to hfrsv was compared with that of five other laboratory and wild animals.19836138015
[etiology of epidemic hemorrhagic fever]. 19836138158
epidemic hemorrhagic fever with renal syndrome. a broadening horizon.a virus identical to or closely related to the viruses of the epidemic hemorrhagic fevers and/or nephropathia epidemica has been demonstrated serologically in rats from geographically separate areas of this country by three groups of investigators. this information suggests a previously unrecognized health threat that should be considered in the differential diagnosis of patients initially seen with febrile illnesses and acute renal failure. the salient features of these viral diseases and the c ...19836139987
morphological evidence for identifying the viruses of hemorrhagic fever with renal syndrome as candidate members of the bunyaviridae family. brief report.thin section immuno-electron microscopy has been successfully applied to investigate and identify the classical and mild form of hfrs viruses isolated in the people's republic of china. the results showed that all the 8 strains studied (derived from different parts of china, adapted in different cell lines) share a common morphology and morphogenesis. essentially, the viruses possess characteristics of members of the bunyaviridae family, however, differing by a larger size and size variation and ...19836139996
simple procedure for preparation of bluetongue virus and epizootic hemorrhagic disease virus antigens for agar gel immunodiffusion.a simplified procedure was developed for preparing soluble antigen from two related orbiviruses, bluetongue and epizootic hemorrhagic disease viruses, for agar gel immunodiffusion. the antigens gave excellent results in both micro-agar gel diffusion (agar gel precipitin) and macro-agar gel diffusion (bluetongue immunodiffusion). minor modification in the spatial arrangement of reference antisera, commonly utilized in the agar gel immunodiffusion tests, was employed to reduce the possible develop ...19836140269
characterization of hantaan virions, the prototype virus of hemorrhagic fever with renal syndrome.hantaan virus, strain 76-118, was propagated to high titer in a clone of vero cells, and infectious virions were successfully concentrated and purified. infectivity and virus antigenic activity were closely associated with a virus particle that exhibited a sedimentation rate indistinguishable from a representative member of the bunyaviridae. purified virions sedimented to a density of 1.16-1.17 in sucrose and 1.20-1.21 in cesium chloride. detergent disruption of virions resulted in a nucleocapsi ...19836140290
laboratory rat associated outbreak of haemorrhagic fever with renal syndrome due to hantaan-like virus in belgium.hantaan-like virus was identified as the cause of three cases of acute renal failure in staff handling laboratory rats on a belgian university campus. serological studies revealed infected rat strains at different sites on the campus and evidence of past and recent infections in 39 staff members and of infection in 50% of exposed staff. hantaan-reactive antibody was very rare in control populations. staff or rats at three other belgian institutions had no signs of infection. the origin of the vi ...19836140543
diagnosis of epidemic and sporadic interstitial nephritis due to hantaan-like virus in belgium. 19836140577
[stratum of the population of the bashkir assr with natural immunity to hemorrhagic fever with renal syndrome].natural immunity to hemorrhagic fever with the renal syndrome (hfrs) in the human population of the bashkir assr having the highest incidence of this infection was first studied using radioimmunoassay. the antigen was a suspension of lungs of rodents from natural foci containing high antigen titres. when 1726 human sera from 8 districts and 2 towns were examined, antibodies to hfrs were found in 20.1%, with variations from 6.9% to 41.5% in different territories. no relationship between the perce ...19836140792
an immune adherence assay for discrimination between etiologic agents of hemorrhagic fever with renal syndrome.antigens of the viruses that cause hemorrhagic fever with renal syndrome (hfrs) and antibodies to these antigens were titrated in an immune adherence hemagglutination (iaha) test and a cf test. vero-e6 cells infected with the sr-11 strain of hfrs virus, an isolate from rats associated with a laboratory outbreak in japan, and the 76-118 strain of hantaan virus, the etiologic agent of korean hemorrhagic fever, were used as antigens in the iaha, cf, and indirect immunofluorescent antibody (ifa) tes ...19846141206
antibodies to the hfrs virus in the human population of european rsfsr as detected by radioimmunoassay.natural immunity to the causative agent of hemorrhagic fever with renal syndrome (hfrs) has first been studied using radioimmunoassay (ria) in the human population of the bashkir assr with the highest incidence of this infection and of five other regions of the rsfsr with lower incidence of hfrs. the antigen was prepared as a suspension of lungs of rodent from natural hfrs foci and contained a high concentration of virus protein. 12,000 sera from the population of 6 areas of the rsfsr were exami ...19846141781
hfrs after a wild rodent bite in the haute-savoie--and risk of exposure to hantaan-like virus in a paris laboratory. 19846142362
antigenic comparison of virus strains of mild and classical types of epidemic haemorrhagic fever isolated in china and adaptation of these to cultures of normal cells. 19846142363
[results and prospects of using immunologic methods in the study and diagnosis of hemorrhagic fever with renal syndrome]. 19836142546
[serologic examination of patients with hemorrhagic fever with renal syndrome in the european part of the ussr].certain features of humoral immunity in patients suffering from hemorrhagic fever with renal syndrome (hfrs) in the territory of the european ussr were established: a trend for increasing antibody levels for a long time after convalescence (approximately 6 months) and the lack of significant decline of antibody levels for many years (5-10). comparative clinico-serological studies revealed the occurrence of subclinical and atypical forms of hfrs disease.19836142566
[indirect hemagglutination test for indicating the hfrs virus and the laboratory diagnosis of the disease].conditions have first been developed for the preparation of erythrocyte immunoglobulin diagnostic preparation of erythrocyte immunoglobulin diagnostic preparation for hfrs virus which permits express detection of the specific virus antigen in suspensions of the lung tissue of rodents by means of the indirect hemagglutination test (iha) and laboratory diagnosis of the infection in humans by means of antibody detection by the indirect hemagglutination-inhibition test (ihai). the iha test is as sen ...19846143451
isolation of a virus related to hemorrhagic fever with renal syndrome from urban rats in a nonendemic area. 19846143783
isolation of the nephropathia epidemica agent in sweden. 19846143925
propagation of nephropathia epidemica virus in cell culture. 19846143926
hfrs outbreak associated with laboratory rats in uk. 19846144891
two cases of hemorrhagic fever with renal syndrome in northern greece.two cases of hemorrhagic fever with renal syndrome were diagnosed in woodcutters presumably exposed to wild rodents and their urine in a forest in northern greece. the disease was characterized by acute renal insufficiency without hemorrhagic manifestations. one patient required hemodialysis, but both recovered without sequelae and developed a fourfold increase in titer of antibody to hantaan virus, as determined by an immunofluorescence test. these are the first reported cases of hemorrhagic fe ...19846145743
hantavirus disease. 19846146051
isolation of hemorrhagic fever with renal syndrome (hfrs) virus from a tumor specimen in a rat.a strain of hemorrhagic fever with renal syndrome (hfrs) virus was isolated in a cell culture from a tumor specimen in a rat kept in a medical institution in which there was a case of hfrs. positive immunofluorescent reaction with sera from hfrs patients was recognized at the second passage and the number of cells containing antigen increased in the third passage. this virus, named b-1 strain, was identified as the hfrs virus by immunofluorescent tests with sera from patients.19836146307
[survey on the reservior for hemorrhagic fever-renal syndrome in yingshang county, anhui province]. 19846146404
nephropathia epidemica in norway: antigen and antibodies in rodent reservoirs and antibodies in selected human populations.nephropathia epidemica (ne) antigen was detected by ifat (indirect fluorescent antibody technique) in the lungs of 14 of 97 bank voles (clethrionomys glareolus) collected in three endemic areas. the distribution of antigen positive voles within an endemic location was scattered. antibodies to korean hemorrhagic fever (khf) virus antigens were detected by ifat in 12 of 14 ne antigen positive bank voles and in 15 of 83 that were antigen negative. ne antigen positive voles exhibited higher antibody ...19846146649
[serological confirmation of cases of hemorrhagic fever with renal syndrome in byelorussia]. 19846147043
[survey on serum hemorrhagic fever-renal syndrome antibody in normal population of zhenjiang prefecture]. 19846147237
scottish case of haemorrhagic fever with renal syndrome. 19846149371
serological evidence for hantaan-related virus in africa. 19846149414
antigenic difference between viral strains causing classical and mild types of epidemic hemorrhagic fever with renal syndrome in china.the antigenic relationship between viral isolates from apodemus and rattus that appear to cause the classical and mild types of epidemic hemorrhagic fever (ehf) in china was studied by cross-immunofluorescence, cross-neutralization, immunofluorescence blocking tests, and cross-enzyme-linked immunosorbent assay (elisa). obvious antigenic diversity between the isolates was demonstrated by cross-neutralization, immunofluorescence blocking tests, and cross-elisa. antisera from patients with classica ...19846150062
hemagglutination-inhibiting antibody in hemorrhagic fever with renal syndrome.hemagglutination activity was demonstrated in a hantaan virus antigen prepared from infected suckling mouse brain by sucrose-acetone extraction. hemagglutination of goose erythrocytes was ph dependent and was optimal at ph 6.0-6.2. immunofluorescent and hemagglutination-inhibiting antibodies were significantly correlated in 80 human and 13 animal sera. hemagglutination-inhibiting antibody was present in some patients 20 years after the onset of hemorrhagic fever with renal syndrome. the hemagglu ...19846150063
haemorrhagic fever virus with renal syndrome in small rodents in czechoslovakia.the antigen of haemorrhagic fever with renal syndrome (hfrs) was detected in the lungs of the following free-living small rodents trapped in different localities in eastern slovakia: clethrionomys glareolus (2 positive samples of 7), apodemus flavicollis (1 sample of 24) and apodemus agrarius (7 positive samples of 66). the virus was first identified by indirect fluorescent antibody (fa) staining using human convalescent serum from a case of epidemic nephropathy (ne) of scandinavia. the lung sus ...19846151356
[natural foci of hemorrhagic fever with renal syndrome in jiangsu province]. 19846152406
[the diagnosis of hemorrhagic fever with renal syndrome using an indirect immunoenzyme histochemical method with horseradish peroxidase-labelled staphylococcus protein a]. 19846152605
antigenic difference between european and east asian viruses causing haemorrhagic fever with renal syndrome. 19816166823
[study of apodemus (agrarius) as a host of epidemic hemorrhagic fever virus and application of apodemus lung antigen for laboratory diagnosis]. 19826192929
determination by immune adherence ha of the antigenic relationship between rattus- and apodemus-borne viruses causing hemorrhagic fever with renal syndrome. 19846201565
[a preliminary observation on the antigen of epidemic hemorrhagic fever virus carried by rodents in linyi prefecture]. 19836202417
isolation and propagation of nephropathia epidemica virus in bank voles.three strains of nephropathia epidemica (ne) virus were isolated from lung tissues of bank voles (clethrionomys glareolus) and a grey-sided vole (c. rufocanus) trapped in västerbotten county, sweden. two of these isolates were serially passaged in seronegative laboratory-bred bank voles. experimentally infected animals developed a subclinical infection characterized by virus persistence, particularly in lung tissue. attempts to infect other species of colonized rodents with ne virus and to isola ...19846208601
[propagation and characterization of the etiologic agent of epidemic hemorrhagic fever in cultured a-549 cells]. 19826216011
features of circulation of hemorrhagic fever with renal syndrome (hfrs) virus among small mammals in the european u.s.s.r.the use of indirect fluorescent antibody testing (ifat) and enzyme linked immunosorbant assay (elisa) procedures allowed the hemorrhagic fever with renal syndrome (hfrs) virus antigen to be detected not only in the known reservoir host, clethrionomys glareolus, but also in 7 other species of small mammals in european foci of the u.s.s.r. marked viscerotropism of hfrs virus and the participation of brown fat in maintaining the infection in rodents were demonstrated. the frequency of detection of ...19836220688
potential reservoir and vectors of haemorrhagic fever with renal syndrome (hfrs) in the u. s. s. r. 19836229222
[identification of hemorrhagic fever-renal syndrome virus isolated from different areas in china by immuno-enzyme electron microscopy--morphological study on various virulent strains]. 19836233018
[studies on growth conditions of ehf virus in primary rat lung cell culture]. 19846241087
[animal reservoirs of epidemic hemorrhagic fever--experimental studies and identification of the specificity of rat lung antigens. cooperative research group for epidemic hemorrhagic fever]. 19846242546
exotic viral diseases.marburg virus disease, lassa fever, monkeypox, and ebola virus diseases of humans have all been recognized since 1967. these are examples of some of the exotic virus diseases which through importation may present a potential public health problem in the united states. some of these viruses are also highly hazardous to laboratory and medical personnel. this paper is a review of the general characteristics, the epidemiology, and laboratory diagnosis of the exotic viruses which have been described ...19806246685
detection of antibody against hemorrhagic fever with renal syndrome (hfrs) virus in sera of house rats captured in port areas of japan. 19836408289
monoclonal antibodies specific for hantaan virus.six hybridoma cell line producing monoclonal antibodies to hantaan virus were established by fusion of ns-1 mouse myeloma cells with spleen cells of mice immunized with hantaan virus strain 76-118. the specificity of these monoclonal antibodies was established by immunoblotting analysis and immunofluorescence. five of the clones reacted with antigens on the cell surface and in the cytoplasm, and one clone reacted with a determinant expressed only in the cytoplasm of the infected cells. two of th ...19836408643
[investigation on the epidemic hemorrhagic fever antigen in rodents captured in benxi city]. 19836411348
[virus--the causative agent of hemorrhagic fever with renal syndrome--a new representative of the family bunyaviridae].physicochemical characteristics (sedimentation coefficient, buoyant density of particles, as well as ribonuclein of these particles) and morphology of the causative agent of hemorrhagic fever with renal syndrome were found to be similar to those of the other members of the bunyaviridae family.19836412459
[experimental animal information file: isolation of epidemic hemorrhagic fever virus]. 19836412637
[morphology of epidemic hemorrhagic fever virus. i. electron microscopic observation of virus in human diploid cell line]. 19836414714
[isolation of the virus of hemorrhagic fever with renal syndrome (hfrs) from the blood of patients using vero e-6 cell culture]. 19836416679
[detection of the viral antigen of hemorrhagic fever with renal syndrome in the lungs of a murine population and a sero-epidemiologic survey]. 19836416680
[detection of the viral antigen of hemorrhagic fever with renal syndrome (hfrs) in apodemus species]. 19836416681
an epidemiological survey of nephropathia epidemica in sweden.the indirect immunofluorescence test (ift) using the hantaan virus (agent of korean hemorrhagic fever, khf) was applied for detection of antibodies to nephropathia epidemica (ne). from 103 patients with symptoms suggesting ne, 61% revealed khf/ne antibodies in the convalescent sera. all seropositive patients seemed to have acquired their disease in ne endemic areas (north of the 60th parallel). only patients found to have a typical clinical ne (fever, abdominal pain and renal engagement) were se ...19836417769
analysis of hantaan virus rna: evidence for a new genus of bunyaviridae.hantaan virus, the prototype virus of hemorrhagic fever with renal syndrome, was examined for nucleic acid characteristics which would support its previously proposed inclusion in the virus family bunyaviridae. nucleocapsid rna from hantaan virions and a control bunyavirus were examined for ribonuclease a (rnase a) sensitivity. both viruses exhibited a similar accessibility of rna within nucleocapsids to digestion by rnase a. complete digestion of the rna of both viruses was affected with high c ...19836419460
[an observation on the persistent period of specific antibodies in epidemic hemorrhagic fever patients' convalescent sera]. 19836426799
[detection of viral antigen in rodents' lung tissue and antibody in patients' sera in the epidemic hemorrhagic fever endemic area of xinye county, henan province]. 19836426800
[prevalence of ectoparasites, endoparasites, bacteria and anti-hantaan virus antibodies in wild rats captured in harbor area of shimizu, japan]. 19846431033
hantaan-like viruses from domestic rats captured in the united states.recent observations that rattus rodents in asia harbor hantaan (htn)-like viruses associated with hemorrhagic fever with renal syndrome led us to investigate the possibility that similar viruses might be present in the united states. wharf rats were captured at major port cities, their sera were examined for htn antibody by immunofluorescent antibody (ifa) assay and tissues from selected antibody-positive rats were examined for htn antigen. rats positive for both antibody and antigen to htn viru ...19846435464
infectivity titration of hemorrhagic fever with renal syndrome virus: use of immune adherence hemagglutination for detection of virus growth.serial dilutions of hemorrhagic fever with renal syndrome viruses were inoculated into vero-e6 cells in microplates. after 2 weeks of incubation, infected cells were disrupted by freezing and thawing, and virus antigens were detected by immune adherence hemagglutination. the infectivity titers of the virus as determined by this method were in close agreement with those obtained by the immunofluorescent antigen endpoint method. then, a neutralization method was established. japanese hemorrhagic f ...19846436305
[isolation of strains of the virus of hemorrhagic fever with renal syndrome in cell culture].four strains of hemorrhagic fever with renal syndrome (hfrs) virus were isolated from the lungs of cl. glareolus caught in natural foci of hfrs in the european ussr. preliminary experiments using enzyme-immunoassay (eia) established the appurtenance of hfrs antigen in lung suspensions to the "western" serotype. four strains were isolated in vero-e6 cell culture after several blind passages and identified as the "western" serotype of hfrs virus. one stram originally isolated in wistar rats and pa ...19846437079
evaluation of focus reduction neutralization test with peroxidase-antiperoxidase staining technique for hemorrhagic fever with renal syndrome virus.titers of hemorrhagic fever with renal syndrome virus were estimated by counting foci stained with peroxidase-antiperoxidase or by using immunofluorescence methods. foci stained with pap were clearer and easier to count. the peroxidase-antiperoxidase method showed a linear relationship between virus concentration and the number of foci. a focus-reduction neutralizing antibody test was performed with immune rat sera and sera from patients. again, the peroxidase-antiperoxidase method proved to be ...19846440908
[hantavirus infections in the netherlands]. 19846441122
isolation in vero-e6 cells of hanta virus from clethrionomys glareolus captured in the bashkiria area of the u.s.s.r. 19846442126
experimental infection in newborn mice and rats by hemorrhagic fever with renal syndrome (hfrs) virus.newborn mice and rats were inoculated intracerebrally (ic) or intraperitoneally (ip) with hantaan virus (76-118 strain) or hfrs-related virus (b-1 strain). the mortality and the influence on the increase of body weight in newborn mice were higher in the groups infected with the 76-118 strain than in the groups infected with the b-1 strain, while the b-1 strain was more virulent in rats than the 76-118 strain. virus isolation from rats inoculated with either strain was attempted 7 and 11 weeks af ...19846442757
observations on natural and laboratory infection of rodents with the etiologic agent of korean hemorrhagic fever.studies were conducted to define the natural host range of the korean hemorrhagic fever (khf) agent in south korea, and to identify colonized rodents susceptible to this infection. eight species of field rodents were captured in areas of korea endemic for khf and their tissues were examined by immunofluorescence for the presence of khf antigen. one hundred and fourteen of 817 apodemus agrarius coreae captured between 1974 and 1978 had one or more positive organs. no positive organ was found in 2 ...19816786119
serum antibodies reactant with korean haemorrhagic fever agent in scandinavian epidemic (endemic) nephropathy (nephropathia epidemica) demonstrated by immunofluorescence utilizing an in vitro antigen source.a newly developed spot slide immunofluorescence method utilizing an in vitro antigen source was used for the first time for the assay of antibodies reactant with the korean haemorrhagic fever (khf) agent in sera from patients diagnosed with scandinavian epidemic (endemic) nephropathy (nephropathia epidemica, ne) and from age-matched control patients living in the same area as the ne patients but suffering from other diseases. khf antibodies were demonstrated in all of 14 ne patients who were fol ...19816797053
hfrs antigen and antibody in two species of swedish voles. 19826819638
antigenic differences between european and east asian strains of hfrs virus. 19826820724
hantavirus nephropathy. 19957474679
[acute, post-transfusion lung injury (trali) and related states]. 19957479263
coexistence of several novel hantaviruses in rodents indigenous to north america.three genetically distinct members of the hantavirus genus have been detected in nevada rodents by rt-pcr and nucleotide sequence analysis. these include sin nombre (sn), el moro canyon (elmc), and prospect hill (ph)-like viruses which are primarily associated with peromyscus maniculatus (deer mouse), reithrodontomys megalotis (western harvest mouse), and microtus spp. (voles), respectively. although this region of the united states is ecologically diverse, rodents infected with different hantav ...19957483255
[epidemic of hantavirus disease in entre-sambre-et-meuse: year 1992-1993. clinical and biological aspects].a multihospital study allowed us to follow a total of 62 serologically proven cases of nephropathia epidemica (ne) in the belgian region between sambre and meuse during the 1992-1993 period. the clinical picture consisted of sudden high fever (100% of the cases), headache (71%), abdominal or lumbar pains (80%) and, as a less frequent but very specific sign, acute myopia (24%). non-specific respiratory symptoms such as a non-productive cough and an abnormal lung auscultation were found in 1 case ...19957483970
rats and hantavirus disease. 19957489373
comparison of the clinical and serologic diagnosis of haemorrhagic fever with renal syndrome (hfrs) and leptospirosis. 19957489781
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