Publications
| Title | Abstract | Year(sorted ascending) Filter | PMID Filter |
|---|
| hemorrhagic fever with renal syndrome: first imported case of hantavirus infection in taiwan. | a patient infected with hantavirus, with resultant hemorrhagic fever with renal syndrome (hfrs), is reported. the patient was a 38-year-old man, living in tainan, taiwan, who had been visiting mainland china for 3 months when he suddenly developed fever and chills, generalized myalgia, abdominal pain and petechiae on his chest. he sought treatment in mainland china. his clinical course progressed through febrile, hypotensive, oliguria and polyuria phases. supportive care included one course of h ... | 1996 | 8772056 |
| analysis of fatal pulmonary hantaviral infection in new york by reverse transcriptase in situ polymerase chain reaction. | the purpose of this study was to analyze the histological distribution of polymerase chain reaction (pcr)-amplified hantaviral cdna in three cases of fatal hantaviral infection that occurred 2 years ago in long island, ny. the three otherwise healthy patients had a rapid death characterized by fever and pulmonary failure and were identified from the autopsy files at university hospital, stony brook. six autopsy controls with either no pulmonary disease (three) or fatal pneumonitis of known etiol ... | 1996 | 8774123 |
| radiologic findings of the hantavirus pulmonary syndrome. | 1996 | 8779215 | |
| hantavirus pulmonary syndrome: epidemiology, prevention, and case presentation of a new viral strain. | hantavirus pulmonary syndrome (hps) is a viral infection from a new strain of hantavirus. the hantavirus was first discovered in north america in 1993 after an outbreak of fatal illness on a navajo indian reservation in new mexico. since then, 122 cases of hps (with a high mortality rate of more than 50%) have been reported in 23 states, with the highest prevalence in the four corners area. the reservoir for hantavirus is small rodents, mostly field mice, vole, and chipmunks. it is transmitted t ... | 1996 | 8784877 |
| direct genetic detection of dobrava virus in greek and albanian patients with hemorrhagic fever with renal syndrome. | blood samples were collected from an albanian and a greek patient with hemorrhagic fever with renal syndrome and tested by reverse transcriptase-polymerase chain reaction. the genetic detection assay amplified hantavirus-specific dna fragments from rna extracted from the blood of the patients; nucleotide sequence analysis revealed that the causative agent of the disease was dobrava virus. these findings suggest that dobrava virus (which was originally isolated from the lungs of an apodenws flavi ... | 1996 | 8699076 |
| a patient with down's syndrome and anti-neutrophilic cytoplasmic antibody-positive vasculitis. | 1996 | 8703724 | |
| [differential diagnosis of hantavirus infection--adult still syndrome]. | 1996 | 8709914 | |
| meeting the public's need for information during the arizona hantavirus outbreak. | 1996 | 8712282 | |
| retrospective diagnosis of hantavirus pulmonary syndrome, 1978-1993: implications for emerging infectious diseases. | to investigate the occurrence of unrecognized cases of hantavirus pulmonary syndrome preceding the detection of the 1993 outbreak in the southwestern united states and the initial description of the syndrome. | 1996 | 8712893 |
| [what do we know about hantavirus?]. | 1996 | 8714190 | |
| serological evidence for zoonotic hantaviruses in north carolina rodents. | in a survey of seven species of wild rodents (n = 423) collected between october 1993 and march 1994 from the three principal ecological biomes of north carolina (usa), we found hantavirus antibodies in seven (2%) of 301 peromyscus spp. hantavirus antibodies were detected in p. leucopus and p. maniculatus captured from mountain and coastal island biomes. three mice were positive for sin nombre virus, while four others had antibodies to seoul virus or a related agent. two mice serologically posit ... | 1996 | 8722278 |
| evidence against person-to-person transmission of hantavirus to health care workers. | unusual, primarily pulmonary, manifestations of hantaviral illness occurring in the southwestern united states raised the possibility of person-to-person transmission of a recently recognized hantavirus, sin nombre virus. to determine whether such transmission had occurred among health care workers (hcws) exposed to patients with confirmed hantavirus pulmonary syndrome, we evaluated hcws who had cared for patients with hantavirus pulmonary syndrome or who had processed specimens from these patie ... | 1996 | 8722939 |
| occupational exposure leading to hantavirus pulmonary syndrome in a utility company employee. | hantavirus pulmonary syndrome is a newly recognized rodent-borne zoonosis. we report a case of hantavirus pulmonary syndrome in an employee of a california utility company who was probably occupationally exposed to sin nombre virus. environmental assessment and genetic comparison of the patient's hantavirus isolates to hantavirus isolates from rodents trapped at possible sites of exposure suggested that the patient contracted his infection at the work site. the study revealed a close corresponde ... | 1996 | 8722943 |
| hanta is coming. | the hanta virus is coming again. yes, it is coming again and again to your town to your rodents and to your homes! we can resolve to prevent it, contain it, and treat it in a scientific and humane way, or we can salivate, scratch, bite, and run like rats and mice and voles and shrews. | 1996 | 8725626 |
| third international conference on haemorrhagic fever with renal syndrome (hfrs) and hantaviruses. | 1996 | 8731183 | |
| retrospective diagnosis of a fatal case of the hantavirus pulmonary syndrome, 1980. | 1996 | 8732742 | |
| [retrospective detection of hantavirus clinical infections in argentina]. | hantavirus activity in rodents and human beings in argentina has been known since the 1980's. in this study, we retrospectively investigated hantavirus infections among argentine hemorrhagic fever (ahf) cases notified between 1987 and 1994, without virological confirmation. igg and igm antibodies to hantavirus were tested by elisa. among 1028 patients included in the study, we found 13 recent infections (1.26%) and 13 remote infections (1.26%). igg antibodies determined in 745 healthy persons li ... | 1996 | 8734923 |
| serological evidence of human hantavirus infection in argentina, bolivia and uruguay. | a serological survey was conducted in 1985-1987 to determine the presence of infection for hantavirus in the general population in argentina, uruguay, paraguay and bolivia, as well as among rodent-exposed laboratory workers in argentina. out of 748 individuals tested by immunofluorescence 20 proved positive for hantaan virus 76/118 strain of whom 16 also reacted against seoul virus 80/39 strain and 2 against puumala virus sotkamo strain. ten out of 72 argentine laboratory workers were positive f ... | 1996 | 8734925 |
| hantavirus pulmonary syndrome--united states, 1995 and 1996. | sporadic cases of hantavirus pulmonary syndrome (hps), a severe cardiopulmonary illness first identified in 1993, continue to be recognized in the united states (1,2). this report describes the investigation of two cases of sin nombre virus (snv)-associated hps involving feedlot workers in a single household during may-june 1995, and summarizes national reporting for hps through march 21, 1996. the findings of this investigation and of other investigations suggest that, although domestic and occ ... | 1996 | 8598827 |
| cytokines, adhesion molecules, and cellular infiltration in nephropathia epidemica kidneys: an immunohistochemical study. | puumala hantavirus-induced nephropathia epidemica (ne) is an important cause for an acute reversible renal failure in scandinavia, european russia, and the balkans. the characteristic histopathological renal finding is an acute tubulointerstitial nephritis. mild to massive proteinuria, hematuria, and a rise in the serum creatinine level are typically seen. the pathogenetic mechanisms of ne kidney failure are incompletely understood. therefore we studied the infiltrating cell populations and loca ... | 1996 | 8599883 |
| histopathology of peromyscus leucopus naturally infected with pathogenic ny-1 hantaviruses: pathologic markers of hps viral infection in mice. | hantavirus research is impeded by the absence of animal models of viral pathogenesis. we have studied the histopathology of mice (p. leucopus) naturally infected with the ny-1 hantavirus on shelter island, new york. five mice were determined to be seropositive in western blotting to four corners virus nucleocapsid protein and had serum antibodies to seoul and puumala hantavirus antigens by immunofluorescence assay. hantavirus gene segments of the ny-1 hantavirus were identified in these mice and ... | 1996 | 8600313 |
| hantavirus pulmonary syndrome. | 1996 | 8602007 | |
| hantavirus infection in taiwan. | 1996 | 8602039 | |
| spread of hantavirus infections in europe. | 1996 | 8602040 | |
| epidemiologic linkage of rodent and human hantavirus genomic sequences in case investigations of hantavirus pulmonary syndrome. | sin nombre virus (snv) causes the zoonotic disease hantavirus pulmonary syndrome (hps). its mechanisms of transmission from rodent to human are poorly understood. it is possible that specific genetic signature sequences could be used to determine the probable site of each case-patient's exposure. environmental assessments suggested 12 possible sites of rodent exposure for 6 hps patients. rodents were captured at 11 of the 12 sites and screened for snv infection within 2 weeks of the patient's di ... | 1996 | 8603954 |
| hantavirus illness in humans: review and update. | hantavirus is a rodent-borne pathogen that has been well characterized since the 1950s in asia and northern europe. the classic hantaviral illnesses hemorrhagic fever with renal syndrome and nephropathia epidemica are indistinguishable from the hantaviral pulmonary syndrome (hps) in early symptoms and laboratory data, but hps goes on to produce the adult respiratory distress syndrome (ards) and usually spares the kidney. hps is the first hantaviral disease reported in humans in the western hemis ... | 1996 | 8604454 |
| cardiopulmonary manifestations of hantavirus pulmonary syndrome. | to describe the clinical characteristics of a group of patients infected with the newly recognized hantavirus in the southwestern united states. | 1996 | 8605797 |
| characterization of puumala virus nucleocapsid protein: identification of b-cell epitopes and domains involved in protective immunity. | b-cell epitopes in the nucleocapsid protein (n) of puumala (puu) virus were investigated by use of truncated recombinant proteins and overlapping peptides. six of seven epitopes, recognized by bank vole monoclonal antibodies, were localized within the amino-terminal region of the protein (aa 1-79). polyclonal antibodies from wild-trapped or experimentally infected bank voles identified epitopes located over the entire protein. antibody end-point titers to different n fragments indicated that the ... | 1996 | 8607269 |
| patterns and predictability in emerging infections. | many seemingly novel infections have a long history as zoonoses, and perhaps in sporadic human hosts; they gain access to new host populations through ecologic changes and human activity. identification of patterns in the emergence of such illnesses--ranging from influenza and lyme disease to ebola fever and aids--suggests that worldwide surveillance may be more feasible than once thought. | 1996 | 8609193 |
| hantaviruses are likely threat to nato forces in bosnia and herzegovina and croatia. | 1996 | 8612216 | |
| hantavirus antigen detection using human serum immunoglobulin m as the capturing antibody in an enzyme-linked immunosorbent assay. | an enzyme-linked immunosorbent assay (elisa) was developed to detect different hantavirus antigens in cell culture; i.e. puumala (puu), hantaan (htn), and dobrava (dob) viruses. the assay was based on binding human serum immunoglobulin m (igm) antibodies to the solid phase by use of goat anti-igm antibodies. the captured igm antibodies were present in the acute phase serum from two patients: one infected in sweden and the other in bosnia. antigens being bound to the solid phase by the human anti ... | 1996 | 8615449 |
| hantaviruses in the united states. | 1996 | 8615702 | |
| human and rodent hantavirus infection in new york state: public health significance of an emerging infectious disease. | a case of hantavirus pulmonary syndrome with possible exposure in new york and/or rhode island was confirmed in february 1994. | 1996 | 8615704 |
| from the centers for disease control and prevention. hantavirus pulmonary syndrome--united states, 1995 and 1996. | 1996 | 8618355 | |
| occurrence of hantavirus within the rodent population of northeastern california and nevada. | these studies were initiated to determine the prevalence and hosts of hantaviruses within the rodent population of nevada and northeastern california. a total of 1,867 rodents were collected, sexed, weighed, identified, and tested by enzyme-linked immunosorbent assay for the presence of antibody against hantavirus nucleocapsid. the primary hosts for hantaviruses in this region were found within the family muridae (peromyscus maniculatus. reithrodontomys megalotis. and microtus montanus). studies ... | 1996 | 8619434 |
| khabarovsk virus: a phylogenetically and serologically distinct hantavirus isolated from microtus fortis trapped in far-east russia. | two hantavirus strains, mf43 and mf113, isolated from microtus fortis trapped in the khabarovsk region of far-eastern russia, were analysed by direct nucleotide sequencing of pcr generated fragments of the m and s segments, by immunofluorescence and by focus reduction neutralization tests (frnt). the nucleotide sequences revealed that the two isolates were closely related to each other but distinct from all other hantaviruses. phylogenetic analysis of the m and s segments showed that the mf stra ... | 1996 | 8627257 |
| hantavirus pulmonary syndrome in germany. | 1996 | 8637377 | |
| western blotting using recombinant hantaan virus nucleocapsid protein expressed in silkworm as a serological confirmation of hantavirus infection in human sera. | recombinant hantaan virus nucleocapsid protein expressed in silkworm larvae was applied as a serological diagnostic antigen in western blots (wb) of human sera. the sensitivity of this method was similar to that of the ifa test. hemorrhagic fever with renal syndrome (hfrs) and nephropathia epidemica diagnosed by their cross-reactivity in wb. the specificity of this method was higher than that of ifa test because the background was low. sera that exhibited high background staining in the ifa test ... | 1996 | 8645761 |
| hantavirus pulmonary syndrome: the first 100 us cases. | in the spring of 1993, hantavirus pulmonary syndrome (hps) "emerged" in the southwestern united states, where a multiagency investigation led to the rapid description of this new clinical entity and its etiology. analysis of the first 100 us cases identified showed that the disease was distributed in 21 states, had gone unrecognized since at least 1959, and had a distinct spring-early summer seasonality. of the infected persons, 54% were male; 63% were caucasian, 35% were native american, and 2% ... | 1996 | 8648200 |
| genetic identification of a new hantavirus causing severe pulmonary syndrome in argentina. | a fatal case of serologically confirmed hantavirus pulmonary syndrome (hps) was recently reported in southwestern argentina. nucleotide sequence analysis of pcr fragments from conserved regions of the s and m genomic segments of the virus, amplified from rna extracted from autopsy lung and liver tissues, showed the virus (referred as andes virus) to be novel. comparisons between andes virus genome sequences with the corresponding sequences of the more closely related hantaviruses revealed differ ... | 1996 | 8659118 |
| sequence-based identification of microbial pathogens: a reconsideration of koch's postulates. | over 100 years ago, robert koch introduced his ideas about how to prove a causal relationship between a microorganism and a disease. koch's postulates created a scientific standard for causal evidence that established the credibility of microbes as pathogens and led to the development of modern microbiology. in more recent times, koch's postulates have evolved to accommodate a broader understanding of the host-parasite relationship as well as experimental advances. techniques such as in situ hyb ... | 1996 | 8665474 |
| newly recognised hantavirus in siberian lemmings. | 1996 | 8667948 | |
| hantavirus pulmonary syndrome in florida: association with the newly identified black creek canal virus. | hantavirus pulmonary syndrome (hps) is a recently recognized viral zoonosis. the first recognized cases were caused by a newly described hantavirus. sin nombre virus (previously known as muerto canyon virus), isolated from peromyscus maniculatus (deer mouse). we describe a 33-year-old floridian man who resided outside the ecologic range of p maniculatus but was found to have serologic evidence of a hantavirus infection during evaluation of azotemia associated with adult respiratory distress synd ... | 1996 | 8579086 |
| inhibition of bunyaviruses, phleboviruses, and hantaviruses by human mxa protein. | viruses of the bunyaviridae family cause a variety of diseases ranging from uncomplicated fever to potentially lethal encephalitis and hemorrhagic fever. little is known about the factors determining pathogenicity in the vertebrate host. interferons have been reported to be inhibitory, but their mode of action against members of the bunyaviridae has not yet been elucidated. the interferon-induced mxa protein encoded on human chromosome 21 is a large gtpase with antiviral activity against distinc ... | 1996 | 8551631 |
| utility of emergency, telephone-based national surveillance for hantavirus pulmonary syndrome. hantavirus task force. | on may 27, 1993, in response to the outbreak investigation of newly recognized hantavirus pulmonary syndrome (hps) in the four corners states (new mexico, arizona, utah, and colorado), the centers for disease control and prevention established a national surveillance case definition for severe, unexplained respiratory disease to determine the extent of hps throughout the united states. a toll-free telephone hotline number was instituted to provide updated information about unexplained respirator ... | 1996 | 8569020 |
| hantavirus outbreak during military manoeuvres in germany. | 1996 | 8569401 | |
| hantavirus pulmonary syndrome in germany. | 1996 | 8569402 | |
| lessons learned from the hantaviruses and other hemorrhagic fever viruses. | in recent years, numerous previously known infections pathogens and their associated diseases have been recognized. among these newly identified agents are the viruses that cause the hemorrhagic fevers, including sin nombre virus, the etiologic agent of the 1993 outbreak of hantavirus pulmonary syndrome in the american southwest. epidemiologic and laboratory investigations of the hemorrhagic fevers and their etiologic agents provide lessons that may be used collectively as a paradigm of the natu ... | 1996 | 8571987 |
| a soldier in respiratory distress. | 1996 | 8531548 | |
| hantavirus pulmonary syndrome-related virus from bolivia. | 1996 | 8531560 | |
| ehrlichia infection as a cause of severe respiratory distress. | 1996 | 8532017 | |
| hantavirus serologies in patients hospitalized with community-acquired pneumonia. | in many patients, the etiology of community-acquired pneumonia is not known but may be caused by previously undescribed pathogens in some cases. the recently identified hantavirus sin nombre (sn) causes hantavirus pulmonary syndrome. because sporadic cases have occurred outside the range of its reservoir (the deer mouse peromyscus maniculatus), an investigation sought to determine whether hantaviruses contributed to cases of community-acquired pneumonia in a large baltimore hospital. acute-phase ... | 1996 | 8537665 |
| elevated plasma levels of tumor necrosis factor (tnf)-alpha, soluble tnf receptors, interleukin (il)-6, and il-10 in patients with hemorrhagic fever with renal syndrome. | plasma levels of cytokines were measured by eia in 15 subjects hospitalized with nephropathia epidemica, a european form of hantavirus-induced hemorrhagic fever with renal syndrome. concentrations of tumor necrosis factor (tnf)-alpha and interleukin (il)-6 were increased in all patients at admission, and the concentration of il-10 was increased in most. tnf-alpha concentrations were still increased 1 week after onset of disease; levels of il-6 and il-10 were normalized. tnf-alpha was undetectabl ... | 1996 | 8537680 |
| enhancing laboratory detection of disease. part 2: amplifying information and requisite variety. | 1997 | 10172959 | |
| enhancing laboratory detection of disease. part 3: detecting a hantavirus disease event: a case study. | a purposive syndromic classification diagnostic system, with known means to ends, has been developed that extracts bits of structural information from endogenous laboratory data. an edifice of structural information for organization, regulation, and decision-making was built for determining future pathophysiological events by asking the fewest questions to define the next event uniquely. the structural information is based on laboratory ordering patterns of physicians for patient populations the ... | 1997 | 10173024 |
| the enigmatic haemorrhagic fevers. | 1997 | 9496275 | |
| hantavirus pulmonary syndrome in the province of rio negro, argentina, 1993-1996. | early in 1995 the first case of hantavirus pulmonary syndrome was serologically confirmed in el bolsón (province of río negro, argentina), corresponding to the third outbreak reported in argentina. a total of 26 cases of hps related to the andean region of rio negro province, were reported from 1993 to 1996, 17 in el bolsón, 4 in san carlos de bariloche, and 5 in buenos aires. the incidence rate was 5.03 x 100,000 with a mortality rate of 51.85 x 100. the occurrence of cases was mainly seasonal, ... | 1997 | 9640780 |
| hantavirus pulmonary syndrome. report of the first three cases in são paulo, brazil. | the hantavirus pulmonary syndrome was first recognized in cases that occurred in the u.s. in 1993, which served as an alert not only for american physicians but also for physicians in other countries for the identification of the disease. in the city of são paulo, brazil, 3 cases of the syndrome were recorded in 1993. the patients were young brothers residing in the mata atlântica (atlantic forest) region submitted to recent deforestation. two of the patients died of acute respiratory insufficie ... | 1997 | 9640788 |
| hantavirus pulmonary syndrome in the rural area of juquitiba, são paulo metropolitan area, brazil. | 1997 | 9640790 | |
| [the pulmonary syndrome produced by hantaviruses]. | 1997 | 9654969 | |
| [the history of the identification of pulmonary syndrome due to hantavirus in the argentina southern andes]. | 1997 | 9674235 | |
| polarized entry and release in epithelial cells of black creek canal virus, a new world hantavirus. | black creek canal (bcc) virus is a newly identified hantavirus from florida which is carried by the cotton rat (sigmodon hispidus) and is associated with hantavirus pulmonary syndrome (hps). we have investigated the interaction of bcc virus with polarized epithelial cells to examine whether entry and release of this virus occur at specific plasma membrane domains. the polarized vero c1008 monkey kidney cell line was grown on permeable filters and infected with bcc virus either through the apical ... | 1997 | 8995636 |
| the evolution of hantaviruses. | hantaviruses exist in most regions of the world. the many different strains identified thus far have widely divergent roles in human disease and infect a wide range of rodent hosts. the sequence data available for the genomes of these viruses allows us to study indirectly the evolutionary patterns of the hantaviruses. in this paper, we describe relationships among the m genomic segments of hantaviruses, and attempt to relate these to the evolutionary relationships of the virus' rodent hosts. | 1997 | 9037623 |
| rapid and specific detection of sin nombre virus antibodies in patients with hantavirus pulmonary syndrome by a strip immunoblot assay suitable for field diagnosis. | to develop a rapid antibody test for sin nombre hantavirus (snv) infection for diagnosis of hantavirus pulmonary syndrome (hps) in field settings where advanced instrumentation is not available, a strip immunoblot assay bearing four immobilized antigens for snv and a recombinant nucleocapsid protein antigen of seoul hantavirus (seov) was prepared. the snv antigens included a full-length recombinant-expressed nucleocapsid (n) protein (rn), a recombinant-expressed g1 protein (residues 35 to 117), ... | 1997 | 9041397 |
| pathogenetic and clinical aspects of the renal involvement in hemorrhagic fever with renal syndrome. | hemorrhagic fever with renal syndrome is the most common clinical manifestation of hantavirus infection. the main target organ is the kidney, resulting in an interstitial hemorrhagic nephritis and sometimes acute tubular necrosis. the pathogenesis is still largely unknown, but several recent studies indicate an important role for immune mechanisms including increased expression of cytokines, for example, tumor necrosis factor. immunohistochemical studies of kidney biopsies have revealed deposits ... | 1997 | 9044447 |
| hantavirus pulmonary syndrome in wisconsin. | in the spring of 1993 an outbreak of a new illness caused by a new pathogen was identified in the southwestern united states. this infection struck relatively young, healthy individuals, was characterized by fever, myalgias, respiratory failure, and a high mortality rate. this illness was caused by a new hantavirus and has been termed hantavirus pulmonary syndrome (hps). the virus is carried by rodents, shed in saliva, urine, and feces. human infection occurs through inhalation of aerosolized vi ... | 1997 | 9046232 |
| hantavirus infection. | 1997 | 9048125 | |
| [hantavirus: an ignored pandemic in switzerland?]. | as numerous publications attest, knowledge on hantaviruses progressed rapidly since the isolation of the agent of korean hemorrhagic fever in 1978. this trend was even enhanced after the recognition of a previously unknown hantavirus that caused an outbreak of acute respiratory distress syndromes in the southwestern united states in 1993. hantaviruses are carried by rodents worldwide and may cause severe diseases in humans. hantavirus pulmonary syndrome in the new world and hemorrhagic fever wit ... | 1997 | 9082534 |
| phylogenetic methods come of age: testing hypotheses in an evolutionary context. | the use of molecular phylogenies to examine evolutionary questions has become commonplace with the automation of dna sequencing and the availability of efficient computer programs to perform phylogenetic analyses. the application of computer simulation and likelihood ratio tests to evolutionary hypotheses represents a recent methodological development in this field. likelihood ratio tests have enabled biologists to address many questions in evolutionary biology that have been difficult to resolv ... | 1997 | 9092465 |
| phage-displayed peptide targeting on the puumala hantavirus neutralization site. | we have selected ligands for puumala hantavirus, the causative agent of nephropathia epidemica, from a seven-amino-acid peptide library flanked by cysteines and displayed on a filamentous phage. to direct the selection to areas on the virus particle which are essential for infection, phages were competitively eluted with neutralizing monoclonal antibodies specific for the viral glycoproteins. the selected phage populations were specific for the same sites as the antibodies and mimicked their fun ... | 1997 | 9094664 |
| hantavirus pulmonary syndrome. | the objective of this report is to summarize the medical literature relevant to the epidemiology, diagnosis, treatment, and control of hantavirus pulmonary syndrome (hps). the english language literature was searched from january 1993 through march 1995, manually and using medline, including conference proceedings and reference lists. we selected relevant articles on clinical aspects of hps. hps is a newly described illness that progresses through three phases: prodromal, cardiopulmonary, and co ... | 1997 | 9097374 |
| experimental evaluation of rodent exclusion methods to reduce hantavirus transmission to humans in rural housing. | an experimental assessment of methods to reduce rodent infestations in rural housing was conducted in yosemite national park, california, sequoia/kings canyon national parks, california, and shenandoah national park, virginia. during pretreatment surveys, nearly all (63 of 68) selected units had past or ongoing rodent activity inside. active infestations were found in 58.8% of the units. peromyscus spp. represented 91.2% of all animals caught inside housing units. despite little harborage, roden ... | 1997 | 9158040 |
| playing in a scrapyard and acute renal failure. | 1997 | 9164319 | |
| assessment of occupational risk for hantavirus infection in arizona and new mexico. | differentiating occupational exposure from other potential domestic or recreational exposure(s) for sin nombre virus (snv) infection is an epidemiologic challenge. interviews on work-related activities were conducted, and serum specimens were obtained from 494 workers in arizona and new mexico. these workers may have been exposed to rodents and rodent excreta at work, but their primary occupation did not require rodent contact (national park service [n = 193]; navajo agricultural product industr ... | 1997 | 9172092 |
| patterns of association with host and habitat: antibody reactive with sin nombre virus in small mammals in the major biotic communities of the southwestern united states. | the distribution and prevalence of antibody reactive with sin nombre virus were determined in mammals in biotic communities of the southwestern united states. small mammals (n = 3,069) of 69 species were trapped in nine communities from lower sonoran desert to alpine tundra. antibody was found in rodents from all communities (overall prevalence = 6.3%); prevalence was lowest at the altitudinal and climatic extremes (0.4% in desert and 2.0% in alpine tundra). antibody occurred in 11% of 928 deer ... | 1997 | 9129529 |
| single amino acid substitutions in puumala virus envelope glycoproteins g1 and g2 eliminate important neutralization epitopes. | two monoclonal antibody escape virus mutants (mars), rescued from a human mab to glycoprotein 2 (g2) and a bank vole monoclonal antibody (mab) directed to glycoprotein 1 (g1) of puumala virus, strain sotkamo, were produced by using a combination of neutralization tests and antigen detection. the mars and the original virus were analyzed by nucleotide sequencing and the responsible mutations were defined and characterized. the g1 mutation was found to constitute an a to t nucleotide substitution, ... | 1997 | 9140197 |
| dobrava hantavirus in estonia: does the virus exist throughout europe? | 1997 | 9149707 | |
| hantavirus infections. | 1997 | 9003738 | |
| emerging infectious diseases: a challenge to all. | emerging infections are defined as diseases of infectious origin with an incidence that has increased within the past two decades or threatens to increase in the near future. some of these diseases are associated with newly discovered infectious agents; others are well-known conditions rapidly increasing in incidence. five emerging infections are reviewed in this article: ehrlichiosis, a tick-borne infection caused by obligate intraleukocytic bacteria; infections caused by vancomycin-resistant e ... | 1997 | 9012271 |
| the english sweating sickness, 1485 to 1551. | 1997 | 9023099 | |
| new hantaviruses causing hantavirus pulmonary syndrome in central argentina. | 1997 | 9100632 | |
| common questions about hantavirus pulmonary syndrome. | 1997 | 9103926 | |
| puumala hantavirus genome in patients with nephropathia epidemica: correlation of pcr positivity with hla haplotype and link to viral sequences in local rodents. | reverse transcription-pcr was used to analyze specimens from 20 finnish nephropathia epidemica (ne) patients hospitalized during the period from october 1994 to january 1995. blood and/or urine sediment specimens from seven patients were found to be positive for the genome sequences of puumala hantavirus (puu). pcr positivity of the specimens from the patients correlated well with the hla-drb1*0301 and hla b8 alleles, which previously were shown to associate with severe courses of ne. genetic an ... | 1997 | 9114386 |
| serological diagnosis of hantavirus infections by an enzyme-linked immunosorbent assay based on detection of immunoglobulin g and m responses to recombinant nucleocapsid proteins of five viral serotypes. | worldwide, hantaviruses cause more than 100,000 human infections annually. rapid and accurate methods are important both in monitoring acute infections and for epidemiological studies. we and others have shown that the amino termini of hantavirus nucleocapsid proteins (ns) are sensitive tools for the detection of specific antibodies in hantavirus disease. accordingly, we expressed truncated ns (amino acids 1 to 117) in escherichia coli from the five hantaviruses known to be pathogenic to man; ha ... | 1997 | 9114393 |
| hantavirus in argentina. | 1997 | 9121542 | |
| [further study of hantavirus circulation in the russian federation]. | lung specimens of 1514 small mammals of 35 species captured in 1991-1995 at 9 territories of russia were tested in elisa for virus antigens of hemorrhagic fever with the renal syndrome (hfrs). the antigens were detected in lung specimens of clethrionomys glareolus, microtus arvalis, microtus gregalis, microtus fortis, arvicola terrestris, apodemus agrarius, micromys minutus, and sorex sp., well known as hantavirus reservoirs, captured in the vologda, yaroslavl, saratov, astrakhan, and chita regi ... | 1997 | 9182404 |
| incidence, etiologic pathogens, and diagnostic testing of community-acquired pneumonia. | determination of the etiologic pathogens of community-acquired pneumonia has been problematic because of the lack of reliable rapid laboratory diagnostic tools as well as the controversy concerning diagnostic criteria. in the studies reviewed here, a specific pathogen was identified in 39% to 88% of patients. streptococcus pneumoniae remains the most common cause of community-acquired pneumonia. depending on the demographics of the study, between 2% to 43% of cases have been attributed to legion ... | 1997 | 9193852 |
| atypical pathogen pneumonia. | the term atypical pathogens has been applied in recent years to chlamydia pneumoniae, mycoplasma pneumoniae, and the various species of legionella. the incidence of pneumonia caused by these pathogens has increased with the development of specific diagnostic techniques. atypical pathogen community-acquired pneumonia demonstrates a broad spectrum of severity from a mild disease not requiring hospitalization to adult respiratory distress syndrome necessitating mechanical ventilation. the clinical, ... | 1997 | 9193855 |
| hantaviruses: four years after four corners. | hantavirus pulmonary syndrome is an acute, often fatal, febrile illness causing rapid pulmonary failure and cardiovascular instability. since first described in 1993, considerable progress has been made in identifying the hantaviruses responsible for the disease and in defining its epidemiologic and diagnostic features. | 1997 | 9194804 |
| hantaviruses: a global disease problem. | hantaviruses are carried by numerous rodent species throughout the world. in 1993, a previously unknown group of hantaviruses emerged in the united states as the cause of an acute respiratory disease now termed hantavirus pulmonary syndrome (hps). before than, hantaviruses were known as the etiologic agents of hemorrhagic fever with renal syndrome, a disease that occurs almost entirely in the eastern hemisphere. since the discovery of the hps-causing hantaviruses, intense investigation of the ec ... | 1997 | 9204290 |
| an unusual hantavirus outbreak in southern argentina: person-to-person transmission? hantavirus pulmonary syndrome study group for patagonia. | hantavirus pulmonary syndrome is a rodent-borne zoonosis first recognized in the united states in 1993. person-to-person transmission has not been reported; however, in the outbreak of 20 cases reported here, epidemiologic evidence strongly suggests this route of transmission. | 1997 | 9204298 |
| seroepidemiologic studies of hantavirus infection among wild rodents in california. | a total of 4,626 mammals were serologically tested for antibodies to sin nombre virus. all nonrodent species were antibody negative. among wild rodents, antibody prevalence was 8.5% in murids, 1.4% in heteromyids, and < 0.1% in sciurids. of 1,921 peromyscus maniculatus (deer mice), 226 (11.8%) were antibody positive, including one collected in 1975. the highest antibody prevalence (71.4% of 35) was found among p. maniculatus on santa cruz island, off the southern california coast. prevalence of ... | 1997 | 9204301 |
| the hantaviruses of europe: from the bedside to the bench. | in europe, hantavirus disease can hardly be called an emerging zoonosis; it is rather a rediscovered disease. since 1934 an epidemic condition with primarily renal involvement has been described in sweden. nowadays, hundreds to thousands of cases per year are registered in fennoscandia, fluctuating with the numbers of the specific arvicoline-rodent reservoir, the red bank vole, which carries the main european serotype, puumala (puu). in the early 1980s, the rat-transmitted serotype, seoul (seo), ... | 1997 | 9204306 |
| virus zoonoses--a long-term overview. | 1997 | 9208195 | |
| a major antigenic domain of hantaviruses is located on the aminoproximal site of the viral nucleocapsid protein. | hantavirus nucleocapsid protein has recently been shown to be an immunodominant antigen in hemorrhagic with renal syndrome (hfrs) inducing an early and long-lasting immune response. recombinant proteins representing various regions of the nucleocapsid proteins as well as segments of the g1 and the g2 glycoproteins of hantavirus strains cg18-20 (puumala serotype) and hantaan 76-118 have been expressed in e. coli. the antigenicity of these proteins was tested in enzyme immunoassays and immunoblots ... | 1997 | 9208453 |
| ecological monitoring helps researchers study disease in environmental context. | 1997 | 9218651 | |
| [of mice and men: social impact of an emerging illness]. | in response to unexplained deaths in an indian reserve of the southwestern united states, a fascinating scientific investigation rapidly led to the identification of a new infectious syndrome, the "hantavirus pulmonary syndrome". the health promotion campaign that followed was remarkable for its large scale and for the efficiency of its delivery, but was not well received by the people on the reserve. this article demonstrates that the preventive guidelines were incompatible with the natives' po ... | 1997 | 9254276 |
| puumala type hantavirus infection with early choleriform syndrome and severe multiorgan failure. | 1997 | 9255656 | |
| genetic characterization and phylogeny of andes virus and variants from argentina and chile. | andes virus, one of five hantaviruses known to cause hantavirus pulmonary syndrome (hps), emerged in 1995 in southwestern argentina (lópez et al. (1996) virology 220, 223-226). the complete nucleotide sequence of andes virus s genome segment was determined and compared with sequences of viral rnas in autopsy tissues of more recently reported hps cases from southwestern argentina and south of chile (cases esq h-1/96 and ch h-1/96). andes virus s segment was found to be 1876 nucleotides in length ... | 1997 | 9255937 |
| mosaic hepatitis b virus core particles allow insertion of extended foreign protein segments. | because of its particular immunological properties, the core protein of hepatitis b virus (hbcag) has become one of the favoured 'virus-like particles' for use as a carrier of foreign epitopes. a new strategy to construct core particles presenting extended foreign protein segments was established based on the introduction of a linker containing a translational stop codon between sequences encoding a c-terminally truncated hbcag (hbcag delta) and a foreign protein sequence. expression in an esche ... | 1997 | 9267006 |