leads from the mmwr. rabies postexposure prophylaxis with human diploid cell rabies vaccine: lower neutralizing antibody titers with wyeth vaccine. | | 1985 | 3974025 |
[vaccination against rabies: optimal combination of doses for vaccine injections]. | | 1985 | 3988776 |
rabies virus interaction with various cell lines is independent of the acetylcholine receptor. | rabies virus infects most cells in vitro. the presence of the nicotinic acetylcholine receptor on the plasma membrane of various cell lines is not an obligate factor for rabies virus susceptibility of those cells. | 1985 | 3994518 |
persistent infection of rabies virus (hep-flury strain) in human neuroblastoma cells capable of producing interferon. | apparent interferon-mediated persistent infection of rabies virus (hep-flury strain) was established in a human neuroblastoma sym-i (clone k-104) cell line, which had the ability to produce interferon. this infection produced variable but small amounts of progeny virus and interferon (up to 100 iu/ml), and resisted superinfection with vesicular stomatitis virus (vsv) and sindbis virus as well as homologous rabies virus. the treatment of this infection with anti-interferon antibody stimulated vir ... | 1985 | 3998711 |
a descriptive epidemiological study of raccoon rabies in a rural environment. | a recent outbreak of rabies in raccoons, procyon lotor (l.), in loudoun county, virginia (1981-82), prompted a study of the epidemiology of the disease. parameters studied included the occurrence and movement of the disease over time, sex and age relationships, and behavior patterns of raccoons. during the 18 mo, 427 raccoons were tested, of which 75% were infected with rabies virus. interpretation of rainfall data and the subsequent spatial occurrence of infected raccoons within the county indi ... | 1985 | 3999245 |
changes recommended in use of human diploid cell rabies vaccine. | | 1985 | 3999343 |
pre-exposure rabies immunization with human diploid cell vaccine: decreased antibody responses in persons immunized in developing countries. | in november 1982, a u.s. peace corps volunteer in kenya completed pre-exposure rabies prophylaxis with a standard 3 dose intradermal (id) series of human diploid cell rabies vaccine (hdcv). in may 1983, she was bitten by a dog and died of rabies 3 months later. an initial investigation revealed that the patient, as well as 9 of 11 others immunized at the same time, had no rabies antibody titers (less than 1:5). we therefore instituted investigations into the immunogenicity of pre-exposure hdcv b ... | 1985 | 4003672 |
rhesus diploid rabies vaccine (adsorbed): a new rabies vaccine using frhl-2 cells. | the frhl-2 cell line, a diploid line derived from the lung of a fetal rhesus monkey, was used to prepare a potent rabies vaccine by adapting the kissling strain of rabies virus to frhl-2 cells, growing the virus in quantity, inactivating the virus with beta-propiolactone, and concentrating the virus by adsorption to aluminum phosphate. high levels of antibody to rabies virus, induced by the vaccine in both guinea pigs and humans at 14 days after immunization, were determined to be igg. data from ... | 1985 | 4008986 |
pathogenesis of street rabies virus infections in resistant and susceptible strains of mice. | seven strains of mice were examined to determine why susceptibility differences and variations in clinical central nervous system (cns) disease occurred among these animals after intraperitoneal inoculation of street rabies virus (srv). trace experiments for infectious virus indicated that these differences were associated with restriction of virus replication within the cns. limitation of viral replication appeared to correlate with the antibody response in that prominent serum anti-srv neutral ... | 1985 | 4020967 |
[pre-exposure rabies vaccination using a new duck embryo vaccine]. | an economical, highly purified and concentrated duck embryo rabies vaccine (pdev) was investigated in relation to pre-exposure rabies prophylaxis. the vaccine was injected subcutaneously according to the then prescribed scheme for human diploid cell rabies vaccines (hdcv). additionally, a third dose was given on day 120. serum anti-rabies antibody levels were determined on days 0, 56, 120, und 170. on day 56 all volunteers showed an anti-rabies antibody level of at least 1.0 iu/ml, indicating th ... | 1985 | 4023675 |
cell-mediated immune response to rabies virus in dogs following vaccination and challenge. | peripheral blood lymphocytes (pbl) from non-vaccinated dogs and from dogs either vaccinated intramuscularly (im) or subcutaneously (sc) with an inactivated rabies virus vaccine (rabguard-tc, norden laboratories, lincoln, ne) or intramuscularly with an attenuated rabies virus vaccine (endurall-r, norden laboratories, lincoln, ne) were exposed in vitro to rabies virus. blastogenesis of pbl was measured by incorporation of 3h-thymidine into the dna of proliferating cells in the presence of a subopt ... | 1985 | 4024449 |
rabies virus in salivary glands of raccoons (procyon lotor). | | 1985 | 4032628 |
cell mediated immune response in canine antirabies vaccination. | | 1985 | 4035202 |
a rabies vaccine produced in a non-tumorigenic rabbit cell line. | from the trypsinized skin of a rabbit embryo, a fibroblastic cell line has been obtained (fel cells). the primary seed lot has been established at 11th passage. the tests for tumorigenicity on nu/nu mice were negative (10(4) cell/animal) at passage level 11th and 50th. cell growth and morphology were not altered when 100 passages were performed. fel cells were tested for their susceptibility to rabies virus. the production of virus on fel cells was investigated after infection by the p.v. rabies ... | 1985 | 4043531 |
structural and immunogenic characteristics of rabies immunosomes. | rabies immunosomes are prepared by the anchorage of glycoprotein molecules to preformed liposomes. virosomes are associations of glycoprotein molecules with viral or non viral lipids. virosomes can be obtained spontaneously after removal of the detergent used for lipids solubilization. under the electron microscope immunosomes look like homogenous spherical vesicles (50-60 nm) evenly covered with spikes, although glycoprotein molecule orientation in virosomes is not yet clearly established. in a ... | 1985 | 4043539 |
[comparative study of cellular and humoral immunity as well as of resistance to the rabies virus in rabies vaccination]. | experiments in cba and balb/c mice showed that after vaccination against rabies alongside with humoral immune response there developed a clone of cells sensitized to rabies antigen which, upon a secondary exposure to it, responded by increased blast formation. the immunological memory to the rabies antigen was found to be specific and to persist for up to 100 days (the observation period). immunization of mice with rabies vaccine using various schedules and in combination with interferon inducer ... | 1985 | 4049846 |
[1st experiences with the oral immunization of foxes against rabies in hesse]. | | 1985 | 4052007 |
decreased virulence of recombinant vaccinia virus expression vectors is associated with a thymidine kinase-negative phenotype. | recent advances in molecular genetics have led to the possibility of using large dna viruses, such as vaccinia virus, as a biological delivery system for immunizing man against unrelated disease-causing agents. when live vaccinia virus recombinants expressing the hepatitis b virus surface antigen (hbsag), the influenza a virus haemagglutinin, the herpes simplex virus (hsv) type 1 d glycoprotein, the rabies virus g glycoprotein and the vesicular stomatitis virus g glycoprotein were used for immun ... | 1985 | 4058585 |
comparison of the effects of rabies virus infection and of combined interferon and poly(i).poly(c) treatment on the levels of 2',5'-adenyladenosine oligonucleotides in different organs of mice. | intracellular levels of 2',5'-adenyladenosine oligonucleotides were analyzed in different organs of mice during the course of a rabies virus infection. phosphorylated and nonphosphorylated 2',5'-adenyladenosine oligonucleotides were measured by radioimmunoassay and analyzed further by hplc. as the infection progressed, concentrations of phosphorylated 2',5'-adenyladenosine oligonucleotides increased strongly, reaching their maxima late in the infection. in contrast, concentrations of the nonphos ... | 1985 | 4060581 |
nonspecific immunostimulation against viruses. | a trypsinized preparation from chromogenic selected strain of mycobacterium phlei (nsi) stimulated the recipient immune system non-specifically against a variety of viruses viz. rabies virus (rna virus). marek's disease (dna virus) and foot and mouth disease virus (rna virus) in phylogenetically different hosts like mice, chicks and guinea pigs respectively. investigation into mechanisms of such nonspecific immunostimulation revealed that there was induction of strong cell mediated immune respon ... | 1985 | 4064625 |
effect of concanavalin a on the early events of rabies virus infection of cer cells. | the effect of concanavalin a on rabies virus infection of cer cells was investigated. pretreatment of cer cells with concanavalin a inhibited cellular susceptibility to rabies virus infection. the lectin also was found to be inhibitory when applied after the viral binding step. moreover, the lectin had a direct inhibitory effect on the infectivity of the virion. these lectin-mediated inhibitions could be reversed by alpha-d-methyl-mannopyranoside. these complex effects are discussed with regard ... | 1985 | 4066254 |
rabies pathogenesis: fast times at the neuromuscular junction. | | 1985 | 4067336 |
duration of immunity afforded to cattle by a binary-ethylenimine inactivated rabies vaccine. | | 1985 | 4072487 |
cell-mediated immune response following intracutaneous immunisation with human diploid cell rabies vaccine. | specific cell-mediated immune response (cmir) against rabies antigens was studied in recipients of two regimens of human diploid cell rabies vaccine (hdcv) using the antigen-stimulated lymphocyte transformation test (ltt) as a measure of cmir. reconstituted hdcv could be conveniently used as the in vitro stimulating antigen and the response was antigen-dependent. conventional intramuscular immunization with full-dose hdcv resulted in positive ltt as early as 14 days after starting immunisation, ... | 1985 | 4074475 |
[vaccination prophylaxis--a danaid sieve? a colloquium at the pasteur institute (paris) on rabies vaccination then and today]. | | 1985 | 4076979 |
[a highly efficient, highly purified duck embryo rabies vaccine]. | at the swiss serum and vaccine institute, berne, a highly purified rabies vaccine presenting a high content of effective rabies virus glucoprotein antigen has been developed. the new vaccine is derived from embryonated duck eggs (pdev). immunizations performed according to the post-exposure schedule recommended for potent rabies vaccines by the who (6 injections on days 0, 3, 7, 14, 28 and 90) already induce protective antibody titers on day 14 (greater than 1 iu/ml). use of the latest radioimmu ... | 1985 | 4089577 |
[humoral immunity of persons inoculated with cultured antirabies vaccines according to abridged schedules]. | the production of virus-neutralizing antibodies in high titers has been found to occur in persons immunized with tissue-culture rabies vaccines, concentrated and non concentrated, intramuscularly in a dose of 1 ml in accordance with reduced immunization schedules. | 1985 | 4090828 |
cardiac involvement in human rabies. case report. | | 1985 | 4095451 |
[ecological classification of lyssaviruses]. | | 1985 | 4095980 |
[interference phenomenon between street rabies virus and poliovirus in tissue cultures]. | | 1970 | 4099469 |
electron-microscopic study of the inlusion body in human rabies. | | 1971 | 4099956 |
rabies virus. | | 1970 | 4100061 |
rabies immune globulin (human). clinical trials and dose determination. | | 1971 | 4105880 |
isolation of a hemagglutinating, immunizing, and non-infectious subunit of the rabies virion. | | 1971 | 4107478 |
[the effectiveness of combined vaccination with cultured rabies vaccine and gamma-globulin in experiments on dogs with street virus rabies]. | | 1969 | 4110826 |
rabies. | | 1972 | 4114526 |
radioimmunoassay procedure for rabies binding antibodies. | | 1972 | 4115541 |
activation of lysosomal enzymes in rabies-infected tissue culture cells without accompanying cytopathic effect. | lactic dehydrogenase and beta-glucuronidase were assayed in tissue culture fluids and cellular lysates, respectively, from bhk-21/13s and iota cell cultures infected with rabies virus. activation of lysosomal enzymes was shown from the day 4 of infection on, without any indication of cytopathic effect. | 1971 | 4117292 |
the rabies virus glycoprotein: partial purification and some properties. | | 1973 | 4121434 |
[use of fluorescent antibody technic for the study of development dynamics of the rabies antigen in mouse cns after infection by various strains]. | | 1973 | 4123938 |
rabies. | | 1973 | 4125302 |
application of the plaque assay technique to the study of rabies virus-neutralizing antibody interactions. | | 1973 | 4127063 |
rapid cytopathic effect with rabies virus in fused hamster embryo cells. | | 1973 | 4132691 |
[some immunity parameters in different physiological conditions and following infection of sheep with rabies virus. ii. development of some immunity parameters in lambs]. | | 1973 | 4132767 |
[some immunity parameters in different physiological conditions and following infection of sheep with rabies virus. i. effect of pregnancy and seasons]. | | 1973 | 4132769 |
titration and neutralization of rabies virus (era strain) following its replication in a pig fallopian tube cell line. | the era strain of rabies virus was found to replicate and produce a constant cytopathic effect in a cell line derived from a gilt's fallopian tube. titration and neutralization tests were made by a microtest technique in which one tcid(50) corresponded approximately to one mouse ld(50). | 1974 | 4132964 |
rabies--a brief review of current management. | | 1974 | 4133831 |
evidence for inapparent rabies infection. | | 1974 | 4138244 |
rabies-like neuronal inclusions associated with a neoplastic reticulosis in a dog. | | 1974 | 4139800 |
[light microscopic localization of rabies virus antigen by means of peroxidase-labeled immunoglobulin (on the usefulness of immunoenzyme technique)]. | | 1974 | 4140099 |
criteria for preparing, evaluating, and standardizing iodinated globulins for radioimmunoassay procedures. | procedures were examined for labeling immune globulins with radioactive iodine using chloramine-t as the oxidizing agent. the chloramine-t method was critically evaluated to establish the optimal conditions for preparing iodinated globulins with high specific radioactivities without impairing their immunospecificities for use in in vitro radioimmunoassays. the results showed that the use of 100 mug of chloramine-t per ml, 500 to 1,000 muci of na (125)i per mg of protein, and a 10-min oxidation r ... | 1974 | 4141599 |
myelopathy after duck embryo rabies vaccine. | | 1973 | 4145261 |
[experimental studies of the transmission of rabies virus infection among mice under natural conditions]. | | 1972 | 4145493 |
viscerotropism of rabies-like strains isolated from murine rodents. | | 1973 | 4147142 |
gel chromatographic purification of rabies virus on wide-pore glass. | | 1973 | 4150026 |
[studies on the resistance of "fixed" rabies virus against the most important active components of disinfectants (author's transl)]. | | 1973 | 4150049 |
[rabies in dogs experimentally infected with street virus and immunized with flury lep virus thereafter (author's transl)]. | | 1973 | 4150062 |
[the detrimental effect of formaldehyde upon the immunological efficacy of hempt rabies vaccine (author's transl)]. | | 1973 | 4150107 |
[gamma-aminobutyric acid concentration in the brains of animals infected with fixed rabies virus]. | | 1974 | 4155823 |
fluorometric estimation of antigens (antibodies). | | 1965 | 4160386 |
pathogenesis of skunk rabies virus: rabies inhibiting substance as related to rabies diagnosis. | | 1966 | 4161801 |
recovery of infectious virus from brain tissue of rats treated with antirabic vaccine of semple type. | | 1966 | 4163352 |
studies with cultured brown adipose tissue. 3. a cytochemical study of rabies virus inclusion bodies. | | 1967 | 4165210 |
studies on the mechanism of action and of the semple antirabic vaccine produced by the state vaccine and serum institute, warsaw. | | 1967 | 4168162 |
[fluorescence diagnosis of rabies and its advantages for rabies vaccination]. | | 1966 | 4171966 |
[morphological aspects of rabies virus]. | | 1967 | 4176916 |
[the importance of the ph of the buffer--solvent of acridine orange in the determination of the nucleic acid composition of viral inclusions by the luminescence microscopy technique]. | | 1966 | 4178199 |
[diagnosis of the rabies virus by using the fluorescent antibody technic]. | | 1967 | 4178643 |
rapid diagnosis of viral infections by immunofluorescent staining of viral antigens in leucocytes and macrophages. | | 1968 | 4180876 |
investigating the rabies virus. | | 1969 | 4182033 |
infectivity of fixed impression smears prepared from rabies virus-infected brain. | | 1969 | 4187588 |
viraemia in rabies. | | 1970 | 4189278 |
viraemia in rabies. | | 1970 | 4189315 |
[inter- and post-reproductive spread of fixed rabies virus infection in vivo]. | | 1969 | 4189843 |
who expert committee on rabies: sixth report. | | 1973 | 4196603 |
rabies group-specific ribonucleoprotein antigen and a test system for grouping and typing of rhabdoviruses. | cell-associated ribonucleoprotein (rnp) was isolated from bhk-21 cells infected with several strains of rabies and rabies-related viruses. the rnp-antigen from rabies and related viruses induced the formation of complement-fixing, precipitating, and immunofluorescent antibodies, and proved to be the group-specific antigen common to all rabies viruses. antigens of the envelope which induce virus-neutralizing antibodies are apparently determinative for the serotype of a virus as evidenced by two-w ... | 1973 | 4196634 |
[immunosuppression and role of interferon in hamsters infected with rabies virus]. | | 1973 | 4196777 |
early events in cell-animal virus interactions. | | 1973 | 4200163 |
experimental infection of dogs and monkeys with two rabies serogroup viruses, lagos bat and mokola (iban 27377): clinical, serologic, virologic, and fluorescent-antibody studies. | | 1973 | 4200590 |
[development of rabies virus on embryonal cells of the reptile blind-worm, anguis fragilis l]. | | 1973 | 4204287 |
kotonkan, a new rhabdovirus related to mokola virus of the rabies serogroup. | | 1973 | 4205431 |
characterization of brain-associated rabies neutralizing substance. | | 1974 | 4206247 |
the vaccination of man and other animals against rabies. | | 1973 | 4207636 |
isolation of viruses from wild mammals in west africa, 1966-1970. | | 1974 | 4210769 |
experimental infection of dogs and monkeys with two rabies serogroup viruses, lagos bat and mokola (iban 27377). gross pathologic and histopathologic changes. | | 1973 | 4214315 |
[antigenicity of a soluble antigen (glycoprotein) of purified rables virus, treated with triton x 100]. | | 1974 | 4219162 |
laboratoty techniques in rabies: tissue culture methods. | | 1973 | 4219467 |
laboratory techniques in rabies: the complement fixation test. | | 1973 | 4219468 |
safety precautions in handling rabies virus. | | 1973 | 4219469 |
passive haemagglutination test for rabies antibodies. | | 1973 | 4219471 |
laboratory techniques in rabies: electron microscopy. | | 1973 | 4219473 |
purification of rabies virus and isolation of its components. | | 1973 | 4219474 |
aluminium phosphate method for rabies virus purification. | | 1973 | 4219475 |
a radioimmune assay for rabies binding antibody. | | 1973 | 4219476 |
laboratory technics in rabies: general considerations in vaccine production. | | 1973 | 4219477 |
laboratory techniques in rabies: vaccine for man prepared in human diploid cells. | | 1973 | 4219489 |
laboratory techniques in rabies: tissue culture vaccines for animals. | | 1973 | 4219490 |
laboratory techniques in rabies: the antibody binding test for vaccine potency. | | 1973 | 4219497 |
a rapid method for fluorescein labelling of rabies antibodies. | | 1973 | 4219504 |
laboratory techniques in rabies: cell monolayer plaque test. | | 1973 | 4219505 |